<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article  PUBLIC "-//NLM//DTD Journal Publishing DTD v3.0 20080202//EN" "http://dtd.nlm.nih.gov/publishing/3.0/journalpublishing3.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="3.0" xml:lang="en" article-type="research article"><front><journal-meta><journal-id journal-id-type="publisher-id">OJRA</journal-id><journal-title-group><journal-title>Open Journal of Rheumatology and Autoimmune Diseases</journal-title></journal-title-group><issn pub-type="epub">2163-9914</issn><publisher><publisher-name>Scientific Research Publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.4236/ojra.2014.44030</article-id><article-id pub-id-type="publisher-id">OJRA-51143</article-id><article-categories><subj-group subj-group-type="heading"><subject>Articles</subject></subj-group><subj-group subj-group-type="Discipline-v2"><subject>Medicine&amp;Healthcare</subject><subject> Social Sciences&amp;Humanities</subject></subj-group></article-categories><title-group><article-title>
 
 
  Quality of Life of Patients with Knee Osteoarthritis with Questionnaire OAKHQOL (OsteoArthritis of Knee Hip Quality of Life) in Rheumatology Consultation in Burkina Faso (West Africa)
 
</article-title></title-group><contrib-group><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>ieu-Donné</surname><given-names>Ouédraogo</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="corresp" rid="cor1"><sup>*</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Joelle</surname><given-names>Tiendrébéogo Zabsonré</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Aimé</surname><given-names>Davy Sèvy Kenagnon</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Fulgence</surname><given-names>Kaboré</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Christian</surname><given-names>Compaoré</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Youssouf</surname><given-names>Joseph Drabo</given-names></name><xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Xavier</surname><given-names>Chevalier</given-names></name><xref ref-type="aff" rid="aff4"><sup>4</sup></xref></contrib></contrib-group><aff id="aff1"><addr-line>Department of Rheumatology, Yalgado Ouedraogo University Hospital, Ouagadougou, Burkina Faso</addr-line></aff><aff id="aff3"><addr-line>Department of Internal Medicine, Yalgado Ouedraogo University Hospital, Ouagadougou, Burkina Faso</addr-line></aff><aff id="aff4"><addr-line>Department of Rheumatology, Henri Mondor University Hospital, Paris, France</addr-line></aff><aff id="aff2"><addr-line>Rheumatology Unit, International Polyclinic of Ouagadougou, Ouagadougou, Burkina Faso</addr-line></aff><author-notes><corresp id="cor1">* E-mail:<email>ouedd@yahoo.fr(IO)</email>;</corresp></author-notes><pub-date pub-type="epub"><day>21</day><month>10</month><year>2014</year></pub-date><volume>04</volume><issue>04</issue><fpage>219</fpage><lpage>225</lpage><history><date date-type="received"><day>27</day>	<month>August</month>	<year>2014</year></date><date date-type="rev-recd"><day>27</day>	<month>September</month>	<year>2014</year>	</date><date date-type="accepted"><day>27</day>	<month>October</month>	<year>2014</year></date></history><permissions><copyright-statement>&#169; Copyright  2014 by authors and Scientific Research Publishing Inc. </copyright-statement><copyright-year>2014</copyright-year><license><license-p>This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/</license-p></license></permissions><abstract><p>
 
 
  Objective: To study the quality of life of patients with knee OA with the questionnaire OAKHQOL (OsteoArthritis of Knee Hip Quality Of Life). Patients and Methods: This was a cross-sectional study over a period of six months, in patients with symptomatic knee osteoarthritis. All patients met the clinical and radiological criteria of the ACR. The OAKHQOL questionnaire was used to investigate the quality of life of patients. Results: One hundred and six patients were included. There were 94 (88.7%) women and 12 (11.3%) men with a sex ratio of 0.12. The average age of patients was 55 &#177; 10.4 years. The average pain intensity was 55.1 &#177; 22.4. The majority of patients (69.8%) had stage 3 of Kellgren and Lawrence classification. The dimension “pain” had the lowest normalized score (60.6). There was a significant correlation between the age range of 30 to 40 years and declining mental health (49.5) . The patients with over 60 years of age had a decrease in pain tolerance and reduced social activities. Lequesne score was associated with severe all dimensions except “social support” of the patient. Conclusion: The knee has an impact on quality of life of patients followed in rheumatology by OAKHQOL questionnaire.
 
</p></abstract><kwd-group><kwd>Quality of Life</kwd><kwd> Osteoarthritis</kwd><kwd> Knee</kwd><kwd> Psychometrics</kwd><kwd> Africa</kwd></kwd-group></article-meta></front><body><sec id="s1"><title>1. Introduction</title><p>OsteoArthritis of Knee affects 12.1% of the adult population in the United States [<xref ref-type="bibr" rid="scirp.51143-ref1">1</xref>] . This is a common disease with significant functional impairment, impaired quality of life for the patient and a social cost [<xref ref-type="bibr" rid="scirp.51143-ref1">1</xref>] [<xref ref-type="bibr" rid="scirp.51143-ref2">2</xref>] . It is the second reason for consultation in rheumatology in Saharan Africa and the first location of osteoarthritis in the lower limbs [<xref ref-type="bibr" rid="scirp.51143-ref3">3</xref>] -[<xref ref-type="bibr" rid="scirp.51143-ref8">8</xref>] . Its functional impact is important and appreciated by several scores; the most used ones are the Lequesne score and WOMAC [<xref ref-type="bibr" rid="scirp.51143-ref9">9</xref>] -[<xref ref-type="bibr" rid="scirp.51143-ref11">11</xref>] . Thus, a Lequesne index average of 14.5 or a WOMAC index of 51.3 is an indication for knee arthroplasty [<xref ref-type="bibr" rid="scirp.51143-ref12">12</xref>] .</p><p>Existing instruments focus on symptoms and function without taking into account many other aspects of the impact of the disease perceived by the patient including the quality of life and the psyche of the patient. Several scales have been developed and validated. Among these, only the Arthritis Impact Measurement Scales (AIMS2) and short (AIMS2-SF) [<xref ref-type="bibr" rid="scirp.51143-ref13">13</xref>] [<xref ref-type="bibr" rid="scirp.51143-ref14">14</xref>] and the questionnaire OAKHQOL (OsteoArthritis of Knee Hip Quality of Life) allow the understanding of the social components of the disease [<xref ref-type="bibr" rid="scirp.51143-ref15">15</xref>] [<xref ref-type="bibr" rid="scirp.51143-ref16">16</xref>] ; OAKHQOL questionnaire showed that the quality of life of patients with osteoarthritis of the knee or hip was altered in several of its components [<xref ref-type="bibr" rid="scirp.51143-ref17">17</xref>] . Knee osteoarthritis is considered more common in black African woman [<xref ref-type="bibr" rid="scirp.51143-ref18">18</xref>] . However, few studies have been conducted on the quality of life in these patients with OAKHQOL questionnaire. The purpose of this study was to assess the quality of life of patients with knee osteoarthritis in a black African population.</p></sec><sec id="s2"><title>2. Patients and Methods</title><p>This was a cross-sectional study from January 2013 to June 2013 who concerned all patients received during the study period for symptomatic knee osteoarthritis in Rheumatology consultation at the University Hospital Yalgado Ouedraogo Ouagadougou, Burkina Faso. All patients included in the study met the clinical and radiological criteria of the ACR [<xref ref-type="bibr" rid="scirp.51143-ref19">19</xref>] . They all received a complete clinical examination by the same rheumatologists (ODD and ZTJ). The blood-cell count, erythrocyte sedimentation rate and C reactive protein (CRP) were systematic. Radiography of both knees was performed, incidence face load, schuss, in profile and axial effects at 30 and 60.</p><p>Data were collected on a pre-computerized record containing the socio-demographic and anthropometric parame ters, functional signs, physical and radiographic, the algo-functional index (visual analogy scale, Lequesne index) and scale OAKHQOL. The variables were then analyzed using the Epi-info version 7.0. ANOVA and Fisher's exact test were used for statistical analysis. A probability p &lt; 0.05 was considered statistically significant.</p></sec><sec id="s3"><title>3. Results</title><sec id="s3_1"><title>3.1. General Characteristics of Patients</title><p>One hundred and six patients were recruited during the study period. There were 94 (88.7%) women and 12 (11.3%) men with a sex ratio of 0.12.</p><p>The average age of patients was 55 &#177; 10.4 with extremes of 31 and 80 years. The average age of women was 54.1 &#177; 10.0 years; for men it was 61.7 &#177; 12.2 years (p &lt; 0.05). <xref ref-type="fig" rid="fig1">Figure 1</xref> shows the distribution of patients by age group.</p><p>The mean BMI of our patients was 30.9 &#177; 6.5 kg/m<sup>2</sup> with a range of 15.8 to 45.4 kg/m&#178;. Among the 94 women, 62 (66.0%) were postmenopausal with a mean duration of menopause 10.3 &#177; 7.9 years. Twenty-five (23.6%) patients had a history of knee trauma, 39 (36.8%), arterial hypertension and 10 (9.4%) diabetes mellitus.</p><p>The average intensity of knee pain according to VAS was 55.5/100 &#177; 22.4 with extremes of 10 and 100. Sixty-seven patients (63.2%) had joint stiffness. The average duration of joint stiffness was 2.8 &#177; 7.6 minutes with a range of 1 to 60 minutes. Architectural defects were observed in 39.6% of patients. <xref ref-type="table" rid="table1">Table 1</xref> shows the distribution of patients according to clinical data.</p><p>Radiographically, 74 patients (69.8%) had stage 3 of Kellgren and Lawrence. <xref ref-type="table" rid="table2">Table 2</xref> shows the distribution of patients according to radiographic data.</p><fig id="fig1"  position="float"><label><xref ref-type="fig" rid="fig1">Figure 1</xref></label><caption><title> Distribution of patients by age group</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/4-2040134x6.png"/></fig><table-wrap id="table1" ><label><xref ref-type="table" rid="table1">Table 1</xref></label><caption><title> Distribution of patients according to clinical data</title></caption><table><tbody><thead><tr><th align="center" valign="middle" ></th><th align="center" valign="middle" >Frequency</th><th align="center" valign="middle" >Percentage</th></tr></thead><tr><td align="center" valign="middle" >Knee Pain (n = 106)</td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Bilateral</td><td align="center" valign="middle" >67</td><td align="center" valign="middle" >63.2</td></tr><tr><td align="center" valign="middle" >Left</td><td align="center" valign="middle" >20</td><td align="center" valign="middle" >18.9</td></tr><tr><td align="center" valign="middle" >Right</td><td align="center" valign="middle" >19</td><td align="center" valign="middle" >17.9</td></tr><tr><td align="center" valign="middle" >Joint Stiffness (n = 106)</td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Yes</td><td align="center" valign="middle" >67</td><td align="center" valign="middle" >63.2</td></tr><tr><td align="center" valign="middle" >No</td><td align="center" valign="middle" >39</td><td align="center" valign="middle" >36.8</td></tr><tr><td align="center" valign="middle" >Architectural Defects (n = 106)</td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Absence of Static Disorder</td><td align="center" valign="middle" >64</td><td align="center" valign="middle" >60.4</td></tr><tr><td align="center" valign="middle" >Genu Valgum Unilateral</td><td align="center" valign="middle" >12</td><td align="center" valign="middle" >11.3</td></tr><tr><td align="center" valign="middle" >Genu Valgum Bilateral</td><td align="center" valign="middle" >10</td><td align="center" valign="middle" >9.4</td></tr><tr><td align="center" valign="middle" >Genu Varum Bilateral</td><td align="center" valign="middle" >8</td><td align="center" valign="middle" >7.5</td></tr><tr><td align="center" valign="middle" >Genu Varum Unilateral</td><td align="center" valign="middle" >6</td><td align="center" valign="middle" >5.7</td></tr><tr><td align="center" valign="middle" >Genu Flexum Unilateral</td><td align="center" valign="middle" >4</td><td align="center" valign="middle" >3.8</td></tr><tr><td align="center" valign="middle" >Genu Flexum Bilateral</td><td align="center" valign="middle" >1</td><td align="center" valign="middle" >0.9</td></tr><tr><td align="center" valign="middle" >Genu Recurvatum Unilateral</td><td align="center" valign="middle" >1</td><td align="center" valign="middle" >0.9</td></tr><tr><td align="center" valign="middle" >Crunch (n = 106)</td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Yes</td><td align="center" valign="middle" >59</td><td align="center" valign="middle" >55.7</td></tr><tr><td align="center" valign="middle" >No</td><td align="center" valign="middle" >47</td><td align="center" valign="middle" >44.3</td></tr><tr><td align="center" valign="middle" >Joint Limitation (n = 106)</td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Yes</td><td align="center" valign="middle" >24</td><td align="center" valign="middle" >22.6</td></tr><tr><td align="center" valign="middle" >No</td><td align="center" valign="middle" >82</td><td align="center" valign="middle" >77.4</td></tr></tbody></table></table-wrap></sec><sec id="s3_2"><title>3.2. Description of the Impact of Knee Osteoarthritis</title><sec id="s3_2_1"><title>3.2.1. Impact on Function by the Lequesne Index</title><p>Lequesne average score was 9.1 &#177; 3.6 with a range of 0 to 18. Sixty-seven patients (63.2%) had a score of Lequesne than or equal to 8. <xref ref-type="fig" rid="fig2">Figure 2</xref> shows the distribution of patients according to the Lequesne score.</p></sec><sec id="s3_2_2"><title>3.2.2. Sounding Psycho-Social Scale by OAKHQOL</title><p>The “pain” dimension had the lowest normalized score (60.6). <xref ref-type="table" rid="table3">Table 3</xref> shows the standardized scores of OAKHQOL means and standard deviation. They ranged from 9.4 to 99.4 for physical activity, 4.6 to 98.5 for mental health varies from 0 to 100 for pain and 20.0 to 100 social support.</p><fig id="fig2"  position="float"><label><xref ref-type="fig" rid="fig2">Figure 2</xref></label><caption><title> Distribution of patients according to the Lequesne score</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/4-2040134x7.png"/></fig><table-wrap id="table2" ><label><xref ref-type="table" rid="table2">Table 2</xref></label><caption><title> Distribution of patients according to radiographic data</title></caption><table><tbody><thead><tr><th align="center" valign="middle" ></th><th align="center" valign="middle" >Frequency</th><th align="center" valign="middle" >Percentage</th></tr></thead><tr><td align="center" valign="middle" >Kellgren and Lawrence Classification (n = 106)</td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Stage 0</td><td align="center" valign="middle" >2</td><td align="center" valign="middle" >1.9</td></tr><tr><td align="center" valign="middle" >Stage 1</td><td align="center" valign="middle" >0</td><td align="center" valign="middle" >0</td></tr><tr><td align="center" valign="middle" >Stage 2</td><td align="center" valign="middle" >0</td><td align="center" valign="middle" >0</td></tr><tr><td align="center" valign="middle" >Stage 3</td><td align="center" valign="middle" >74</td><td align="center" valign="middle" >69.8</td></tr><tr><td align="center" valign="middle" >Stage 4</td><td align="center" valign="middle" >30</td><td align="center" valign="middle" >28.3</td></tr><tr><td align="center" valign="middle" >Osteoarthritis of Knee (n = 106)</td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Unicompartmental</td><td align="center" valign="middle" >20</td><td align="center" valign="middle" >18.9</td></tr><tr><td align="center" valign="middle" >Bicompartmental</td><td align="center" valign="middle" >54</td><td align="center" valign="middle" >50.9</td></tr><tr><td align="center" valign="middle" >Tricompartimental</td><td align="center" valign="middle" >32</td><td align="center" valign="middle" >30.2</td></tr></tbody></table></table-wrap><table-wrap id="table3" ><label><xref ref-type="table" rid="table3">Table 3</xref></label><caption><title> Means and standard deviations of the standardized questionnaire scores OAKHQOL</title></caption><table><tbody><thead><tr><th align="center" valign="middle" ></th><th align="center" valign="middle" >Number of Items</th><th align="center" valign="middle" >Average Standardized Score</th><th align="center" valign="middle" >Standard Deviation</th></tr></thead><tr><td align="center" valign="middle" >Physical Activity</td><td align="center" valign="middle" >16</td><td align="center" valign="middle" >62.6</td><td align="center" valign="middle" >17.3</td></tr><tr><td align="center" valign="middle" >Mental Health</td><td align="center" valign="middle" >13</td><td align="center" valign="middle" >66.8</td><td align="center" valign="middle" >18.7</td></tr><tr><td align="center" valign="middle" >Pain</td><td align="center" valign="middle" >4</td><td align="center" valign="middle" >60.6</td><td align="center" valign="middle" >20.0</td></tr><tr><td align="center" valign="middle" >Social Support</td><td align="center" valign="middle" >4</td><td align="center" valign="middle" >75.6</td><td align="center" valign="middle" >20.1</td></tr><tr><td align="center" valign="middle" >Social Activities</td><td align="center" valign="middle" >3</td><td align="center" valign="middle" >75.6</td><td align="center" valign="middle" >22.7</td></tr></tbody></table></table-wrap></sec></sec><sec id="s3_3"><title>3.3. Influence of Different Variables on the Quality of Life</title><p>The young age (30 - 40 years) was statistically associated with the “Mental Health” (49.5) while the dimension above 60 years of age alters the quality of life in the dimensions of pain and social activities. Static disorders including genu-flessum affect the quality of life in all dimensions of the questionnaire OAKHQOL while a severe Lequesne score was associated with all dimensions except the dimension of social support to the patient. <xref ref-type="table" rid="table4">Table 4</xref> shows the distribution of standardized questionnaire OAKHQOL according to patient characteristics scores.</p></sec></sec><sec id="s4"><title>4. Discussion</title><p>This is to our knowledge the first sub-Saharan study of the quality of life with OAKHQOL Questionnaire in patients with knee osteoarthritis. The general characteristics of patients were similar to those of previous studies and other African studies [<xref ref-type="bibr" rid="scirp.51143-ref3">3</xref>] [<xref ref-type="bibr" rid="scirp.51143-ref6">6</xref>] [<xref ref-type="bibr" rid="scirp.51143-ref7">7</xref>] [<xref ref-type="bibr" rid="scirp.51143-ref20">20</xref>] . However, the average age (55 years) of our patients was lower than that of the cohort KHOALA in France (62 years); the body mass index was similar but with an average intensity of the largest pain in our series (55.5/100) than in the cohort KHOALA [<xref ref-type="bibr" rid="scirp.51143-ref21">21</xref>] .</p><p>Static disorders of the knees (genu-flessum) and a high score Lequesne seem to be associated with significant impairment of the quality of life of patients. Similarly, it appears that the over 70 years of age has a significant impact on the “social activities” questionnaire OAKHQOL component. The social activity plays an important role in patients of this age group because of their status as resource persons in the African culture.</p><table-wrap id="table4" ><label><xref ref-type="table" rid="table4">Table 4</xref></label><caption><title> Distribution of standardized questionnaire OAKHQOL according to patient characteristics scores</title></caption><table><tbody><thead><tr><th align="center" valign="middle" ></th><th align="center" valign="middle" >Physical Activity (p<sup>*</sup>)</th><th align="center" valign="middle" >Mental Health (p)</th><th align="center" valign="middle" >Pain (p)</th><th align="center" valign="middle" >Social Support (p)</th><th align="center" valign="middle" >Social Activities (p)</th></tr></thead><tr><td align="center" valign="middle" >Age</td><td align="center" valign="middle" >(0.0619)</td><td align="center" valign="middle" >(0.0234)</td><td align="center" valign="middle" >(0.0263)</td><td align="center" valign="middle" >(0.3390)</td><td align="center" valign="middle" >(0.0006)</td></tr><tr><td align="center" valign="middle" >30 - 40</td><td align="center" valign="middle" >54.5</td><td align="center" valign="middle" >49.5</td><td align="center" valign="middle" >58.7</td><td align="center" valign="middle" >61.3</td><td align="center" valign="middle" >59.7</td></tr><tr><td align="center" valign="middle" >40 - 50</td><td align="center" valign="middle" >70.3</td><td align="center" valign="middle" >69.4</td><td align="center" valign="middle" >70.9</td><td align="center" valign="middle" >76.5</td><td align="center" valign="middle" >87.3</td></tr><tr><td align="center" valign="middle" >50 - 60</td><td align="center" valign="middle" >62.1</td><td align="center" valign="middle" >63.8</td><td align="center" valign="middle" >58.5</td><td align="center" valign="middle" >78.6</td><td align="center" valign="middle" >78.3</td></tr><tr><td align="center" valign="middle" >60 - 70</td><td align="center" valign="middle" >58.5</td><td align="center" valign="middle" >66.7</td><td align="center" valign="middle" >54.3</td><td align="center" valign="middle" >76.2</td><td align="center" valign="middle" >70.7</td></tr><tr><td align="center" valign="middle" >≥70</td><td align="center" valign="middle" >59.0</td><td align="center" valign="middle" >78.3</td><td align="center" valign="middle" >57.2</td><td align="center" valign="middle" >70.8</td><td align="center" valign="middle" >59.2</td></tr><tr><td align="center" valign="middle" >Sex</td><td align="center" valign="middle" >(0.6942)</td><td align="center" valign="middle" >(0.6402)</td><td align="center" valign="middle" >(0.5679)</td><td align="center" valign="middle" >(0.9960)</td><td align="center" valign="middle" >(0.4675)</td></tr><tr><td align="center" valign="middle" >Male</td><td align="center" valign="middle" >64.5</td><td align="center" valign="middle" >69.2</td><td align="center" valign="middle" >63.8</td><td align="center" valign="middle" >75.6</td><td align="center" valign="middle" >71.1</td></tr><tr><td align="center" valign="middle" >Female</td><td align="center" valign="middle" >62.4</td><td align="center" valign="middle" >66.5</td><td align="center" valign="middle" >60.2</td><td align="center" valign="middle" >75.6</td><td align="center" valign="middle" >76.2</td></tr><tr><td align="center" valign="middle" >BMI</td><td align="center" valign="middle" >0.8939</td><td align="center" valign="middle" >(0.1438)</td><td align="center" valign="middle" >(0.9439)</td><td align="center" valign="middle" >(0.7046)</td><td align="center" valign="middle" >(0.0277)</td></tr><tr><td align="center" valign="middle" >&lt;18</td><td align="center" valign="middle" >64.7</td><td align="center" valign="middle" >80.8</td><td align="center" valign="middle" >62.5</td><td align="center" valign="middle" >80.0</td><td align="center" valign="middle" >31.7</td></tr><tr><td align="center" valign="middle" >18 - 25</td><td align="center" valign="middle" >65.6</td><td align="center" valign="middle" >74.5</td><td align="center" valign="middle" >64.3</td><td align="center" valign="middle" >70.2</td><td align="center" valign="middle" >80.9</td></tr><tr><td align="center" valign="middle" >25 - 30</td><td align="center" valign="middle" >61.7</td><td align="center" valign="middle" >67.2</td><td align="center" valign="middle" >62.2</td><td align="center" valign="middle" >77.6</td><td align="center" valign="middle" >72.0</td></tr><tr><td align="center" valign="middle" >≥30</td><td align="center" valign="middle" >61.5</td><td align="center" valign="middle" >62.2</td><td align="center" valign="middle" >60.5</td><td align="center" valign="middle" >76.0</td><td align="center" valign="middle" >78.7</td></tr><tr><td align="center" valign="middle" >Menopause</td><td align="center" valign="middle" >(0.0114)</td><td align="center" valign="middle" >(0.8958)</td><td align="center" valign="middle" >(0.0096)</td><td align="center" valign="middle" >(0.0314)</td><td align="center" valign="middle" >(0.1221)</td></tr><tr><td align="center" valign="middle" >Static Disorders</td><td align="center" valign="middle" >(0.000)</td><td align="center" valign="middle" >(0.000)</td><td align="center" valign="middle" >(0.000)</td><td align="center" valign="middle" >(0.000)</td><td align="center" valign="middle" >(0.000)</td></tr><tr><td align="center" valign="middle" >Genu Flessum</td><td align="center" valign="middle" >50.7</td><td align="center" valign="middle" >45.2</td><td align="center" valign="middle" >20.0</td><td align="center" valign="middle" >73.1</td><td align="center" valign="middle" >50.0</td></tr><tr><td align="center" valign="middle" >Genu Varum</td><td align="center" valign="middle" >54.2</td><td align="center" valign="middle" >61.5</td><td align="center" valign="middle" >46.7</td><td align="center" valign="middle" >75.0</td><td align="center" valign="middle" >68.3</td></tr><tr><td align="center" valign="middle" >Joint Limitation</td><td align="center" valign="middle" >(0.0750)</td><td align="center" valign="middle" >(0.0105)</td><td align="center" valign="middle" >(0.0017)</td><td align="center" valign="middle" >(0.3115)</td><td align="center" valign="middle" >(0.0010)</td></tr><tr><td align="center" valign="middle" >Kellgren Classification (Stage 3)</td><td align="center" valign="middle" >(0.3284)</td><td align="center" valign="middle" >(0.5526)</td><td align="center" valign="middle" >(0.6620)</td><td align="center" valign="middle" >(0.2051)</td><td align="center" valign="middle" >(0.3440)</td></tr><tr><td align="center" valign="middle" >Lequesne Score (Severe)</td><td align="center" valign="middle" >(0.000)</td><td align="center" valign="middle" >(0.0086)</td><td align="center" valign="middle" >(0.000)</td><td align="center" valign="middle" >(0.7825)</td><td align="center" valign="middle" >(0.0001)</td></tr></tbody></table></table-wrap><p>p<sup>*</sup><sup> </sup>probabilit&#233;.</p><p>The normalized values of the different components were higher in our comparison to those of the French series [<xref ref-type="bibr" rid="scirp.51143-ref16">16</xref>] , Spain [<xref ref-type="bibr" rid="scirp.51143-ref22">22</xref>] and Morocco [<xref ref-type="bibr" rid="scirp.51143-ref23">23</xref>] series. The quality of life of patients although reduced, seems better in our series than in those just mentioned. This could be different socio-cultural (greater acceptance of illness) or due to methodological biases. Business data, settings of origin, urban or rural, and living conditions are useful for the interpretation of quality of life scales. The recruitment of our patients was only done in consultation Rheumatology, thus excluding serious surgical consequent having a greater impairment of quality of life. In addition, the psychometric properties and the relevance of the questionnaire OAKHQOL in black African culture are not known. Indeed, we used the French version and it is obvious that some items do not match the black African cultural elements. It is therefore important that we develop a black African version. In addition, OAKHQOL questionnaire is a self-administered [<xref ref-type="bibr" rid="scirp.51143-ref17">17</xref>] . In our study, due to a significant rate of illiteracy, the questionnaire was administered to the patient; this could influence the answers. Further studies are needed with a questionnaire OAKHQOL “tropicalised” and self-administered.</p></sec><sec id="s5"><title>5. Conclusion</title><p>Osteoarthritis of knee has an impact on the quality of life of patients treated in rheumatology consultation in Burkina Faso by OAKHQOL questionnaire. However, this questionnaire should be adapted to the cultural aspects of this part of the world to minimize the methodological biases that may have influenced our results and to understand the real impact of the disease. This would allow a more effective management.</p></sec><sec id="s6"><title>Conflict of Interest</title><p>The authors declare no conflict of interest related to this work.</p></sec><sec id="s7"><title>NOTES</title></sec></body><back><ref-list><title>References</title><ref id="scirp.51143-ref1"><label>1</label><mixed-citation publication-type="other" xlink:type="simple">Dillon, C.F., Rasch, E.K., Gu, Q. and Hirsch, R. (2006) Prevalence of Knee Osteoarthritis in the United States. Arthritis Data from the Third National Health and Nutrition Examination Survey 1991-1994. The Journal of Rheumatology, 33, 2271-2279.</mixed-citation></ref><ref id="scirp.51143-ref2"><label>2</label><mixed-citation publication-type="other" xlink:type="simple">Lanes, S., Lanza, L., Radensky, P., Yood, R., Meenan, R., Walker, A., et al. (1997) Resource Utilization and Cost of Care for Rheumatoid Arthritis and Osteoarthritis in a Managed Care Setting: The Importance of Drug and Surgery Costs. 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