Various soft-tissue lesions of the oral cavity that present as tumors are commonly observed in daily practice. Such benign lesions include irritation fibroma, peripheral ossifying fibroma, pyogenic granuloma, peripheral giant-cell granuloma, salivary gland choristoma, granular cell tumor, verruciform xanthoma, hairy polyp, and mesenchymal tumors such as leiomyoma, rhabdomyoma, schwannoma, neurofibroma, traumatic neuroma, lipoma, hemangioma, and solitary fibrous tumor [1] [2] . In addition, adenomatoid hyperplasia of minor salivary glands, idiopathic hyperplasia of sublingual glands, and various types of malignant lymphoma can also present as polypoid tumor-like lesions [3] -[5] .

Recently, we experienced a very unusual hamartomatous lesion of the minor salivary gland presenting as a pedunculated polyp on the base of the tongue in a 59-year-old woman. To the best of our knowledge, such a case has not previously been reported. Here, we present the case with a brief review of the current literature.

A 59-year-old woman presented with a polypoid mass on the dorsal root of the tongue. She did not complain of pain or tenderness but had a little difficulty swallowing. She had no history of local trauma in the oral cavity such as dental extraction surgery.

On laryngoscopic examination, the mass was a 1.5 × 1.2-cm pedunculated polypoid mass with normal-ap- pearing mucosa arising in the base of the tongue (Figure 1). The tumor was attached to the base of the tongue by a stalk and generally looked benign. The relationship of the tumor and the tongue is illustrated in Figure 1(B). The mass was removed under local anesthesia.

On microscopic examination, it consisted of a lobulated mass of normal salivary glands of mucinous and serous types with loose connective tissue and normal overlying mucosa. Multifocal areas of submucosal soft tissue showed lymphoid hyperplasia that could be considered part of the lingual tonsils. The inner region of the tumor showed skeletal muscle bundles (H&E stain) (Figure 2).

Magnetic resonance imaging performed after surgical removal revealed no suspicious local invasion or remnant tumor in the resected area.

The major differential diagnosis of this case was accessory tongue, adenomatoid hyperplasia of minor salivary glands, and tumorous presentation of idiopathic hyperplasia of sublingual glands. Tongue anomalies such as accessory tongue can be ruled out by the fact that the tumor had not been present since birth [6] . Although our case also had a muscular component in the core of the lesion, it was mainly composed of normal lobulated salivary glands. Adenomatoid hyperplasia of minor salivary glands could also be considered in this case. However, the salivary glands in adenomatoid hyperplasia are more hyperplastic and composed of only mucinous glands [1] . Furthermore, the muscular component in this case cannot be explained by adenomatoid hyperplasia. Idiopathic hyperplasia of sublingual glands can also present as a tumorous lesion; however, it presents as a sessile lesion in the retromolar area and is usually associated with an edentulous condition [3] -[5] .

Because of the anatomical complexity of head and neck region, benign conditions mimicking tumor can be easily

encountered in daily practice. However, hamartoma of minor salivary gland has never been described, and its polypoid presentation is even weirder thing. Although the histologic feature of this lesion favors benign clinical behavior, careful diagnostic workup and differential diagnosis are essential. In future, more cases should be collected to elucidate the etiology and true nature of this lesion.