<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article  PUBLIC "-//NLM//DTD Journal Publishing DTD v3.0 20080202//EN" "http://dtd.nlm.nih.gov/publishing/3.0/journalpublishing3.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="3.0" xml:lang="en" article-type="research article"><front><journal-meta><journal-id journal-id-type="publisher-id">OJMN</journal-id><journal-title-group><journal-title>Open Journal of Modern Neurosurgery</journal-title></journal-title-group><issn pub-type="epub">2163-0569</issn><publisher><publisher-name>Scientific Research Publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.4236/ojmn.2014.44032</article-id><article-id pub-id-type="publisher-id">OJMN-50301</article-id><article-categories><subj-group subj-group-type="heading"><subject>Articles</subject></subj-group><subj-group subj-group-type="Discipline-v2"><subject>Medicine&amp;Healthcare</subject></subj-group></article-categories><title-group><article-title>
 
 
  Congenital Frontal Mature Dermoid Cyst: A Case Report
 
</article-title></title-group><contrib-group><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>ehmet</surname><given-names>Hakan Seyithanoglu</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Kazim</surname><given-names>Dogan</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><xref ref-type="corresp" rid="cor1"><sup>*</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Meliha</surname><given-names>Gundag</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Serdar</surname><given-names>Cevik</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Seref</surname><given-names>Ozturk</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Tolga</surname><given-names>Turan Dundar</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib></contrib-group><aff id="aff2"><addr-line>Department of Neurosurgery, Ardahan State Hospital, Ardahan, Turkey</addr-line></aff><aff id="aff1"><addr-line>Department of Neurosurgery, Faculty of Medicine, Bezmialem Vakif University, Istanbul, Turkey</addr-line></aff><author-notes><corresp id="cor1">* E-mail:<email>drkdogan@yahoo.com(KD)</email>;</corresp></author-notes><pub-date pub-type="epub"><day>17</day><month>09</month><year>2014</year></pub-date><volume>04</volume><issue>04</issue><fpage>186</fpage><lpage>189</lpage><history><date date-type="received"><day>3</day>	<month>August</month>	<year>2014</year></date><date date-type="rev-recd"><day>3</day>	<month>September</month>	<year>2014</year>	</date><date date-type="accepted"><day>30</day>	<month>September</month>	<year>2014</year></date></history><permissions><copyright-statement>&#169; Copyright  2014 by authors and Scientific Research Publishing Inc. </copyright-statement><copyright-year>2014</copyright-year><license><license-p>This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/</license-p></license></permissions><abstract><p>
 
 
  Dermoid cysts are uncommon congenital or acquired developmental cystic malformations that were usually seen in the midline of frontal region and the anterior fontanel. Congenital forms develop from the remnants of the epithelium or ectodermal membranous bone growth line. We report here a case of a congenital frontal dermoid cyst that should be considered in the differential diagnosis of lipoma and neurofibroma. Dermoid cysts should be considered in the differential diagnosis of all nodular cyst-like lesions in the head and neck region. Early recognition and accurate diagnosis by means of Computerized Tomography scan or Magnetic Resonance Imaging facilitate successful treatment.
 
</p></abstract><kwd-group><kwd>Dermoid Cyst</kwd><kwd> Congenital</kwd><kwd> Surgical Procedure</kwd><kwd> Operative</kwd></kwd-group></article-meta></front><body><sec id="s1"><title>1. Introduction</title><p>Dermoid cyst is a cystic teratoma that contains developmentally mature skin complete with hair follicles and sweat glands, sometimes clumps of long hair, and often pockets of sebum, blood, fat, bone, nails, teeth, eyes, cartilage, and thyroid tissue [<xref ref-type="bibr" rid="scirp.50301-ref1">1</xref>] . Dermoid cysts are uncommon congenital or acquired developmental cystic malformations that were usually seen in the midline of frontal region and the anterior fontanel [<xref ref-type="bibr" rid="scirp.50301-ref2">2</xref>] . Congenital forms develop from the remnants of the epithelium or ectodermal membranous bone growth line. We report here a case of a congenital frontal dermoid cyst.</p></sec><sec id="s2"><title>2. Case Report</title><p>1-year-old boy admitted to our department with the complaints of the growing swelling in the midline of frontal region. Neurological and physical examination was unremarkable and anterior fontanelle nearly closed. Computerized Tomography (CT) scan and Magnetic Resonance Imaging (MRI) revealed a bone eroded, 3 &#215; 3.5 cm sized lesion in front of the midline of the anterior fontanelle (<xref ref-type="fig" rid="fig1">Figure 1</xref> and <xref ref-type="fig" rid="fig2">Figure 2</xref>). The relationship between lesion and sagittal sinus was assessed and there was no connection between them. The patient was operated with the prediagnosis of dermoid cyst. The cystic lesion was completely circumscribed and excised without any tearing. Bone erosion was found at the bottom of the cyst (<xref ref-type="fig" rid="fig3">Figure 3</xref>).</p><fig id="fig1"  position="float"><label><xref ref-type="fig" rid="fig1">Figure 1</xref></label><caption><title> Magnetic Resonance Imaging (MRI) revealed a bone eroded, 3 &#215; 3.5 cm sized lesion in front of the midline of the anterior fontanelle</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/5-2080053x6.png"/></fig><fig id="fig2"  position="float"><label><xref ref-type="fig" rid="fig2">Figure 2</xref></label><caption><title> Magnetic Resonance Imaging (MRI) revealed a bone eroded, 3 &#215; 3.5 cm sized lesion in front of the midline of the anterior fontanelle</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/5-2080053x7.png"/></fig><fig id="fig3"  position="float"><label><xref ref-type="fig" rid="fig3">Figure 3</xref></label><caption><title> The cystic lesion was completely circumscribed and excised without any tearing. Bone erosion was found at the bottom of the cyst</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/5-2080053x8.png"/></fig></sec><sec id="s3"><title>3. Discussion</title><p>Adeloye and Xu X.L. described this malformation clearly [<xref ref-type="bibr" rid="scirp.50301-ref3">3</xref>] . Dermoid cyst is a benign cystic teratoma that contains developmentally mature skin complete with hair follicles and sweat glands, sometimes clumps of long hair, and often pockets of sebum, blood, fat, bone, nails, teeth, eyes, cartilage, and thyroid tissue [<xref ref-type="bibr" rid="scirp.50301-ref1">1</xref>] . The cyst fluid should be clear or yellow color. The content of cyst fluid is composed of potassium chloride, sodium and glucose. Dermoid cysts occur as a result of a failure of ectoderm development in the third and fifth week of embryogenesis [<xref ref-type="bibr" rid="scirp.50301-ref4">4</xref>] .</p><p>MRI and CT scan are most effective imaging methods to demonstrate the intracranial or extracranial location of the cyst and relationship between bone tissue and in differential diagnosis. Dermoid cysts should be included in the differential diagnosis of all nodular cyst-like lesions in the head and neck region such as encephalocele, meningocele, hemangioma, lipoma, hematoma, sebaceous cyst, pilonidal cyst and sinus pericranii. In our case cystic lesion was on the extracranial location and MRI and CT scan revealed a bone eroded, 3 &#215; 3.5 cm sized lesion in front of the midline of the anterior fontanelle. The relationship between lesion and sagittal sinus was assessed and there was no connection between them.</p><p>Bartlett et al. defined a treatment algorithm based on the potential extension of the lesions to the contiguous structures. They found that the frontotemporal dermoid cysts with definable margins are superficial, slow-growing masses that can be excised, preferably by a lid crease incision [<xref ref-type="bibr" rid="scirp.50301-ref5">5</xref>] . We used this frontal incision and the cystic lesion was completely circumscribed and excised without any tearing.</p></sec><sec id="s4"><title>4. Conclusion</title><p>Dermoid cysts should be considered in the differential diagnosis of all nodular cyst-like lesions in the head and neck region. Early recognition and accurate diagnosis by means of CT scan or MRI facilitate successful treatment.</p></sec><sec id="s5"><title>Disclosure</title><p>The authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this paper. We have no source or support on this study.</p></sec><sec id="s6"><title>NOTES</title></sec></body><back><ref-list><title>References</title><ref id="scirp.50301-ref1"><label>1</label><mixed-citation publication-type="other" xlink:type="simple">New, G.B. and Erich, J.B. (1937) Dermoid Cyst of the Head and Neck. Surgery, Gynecology Obstetrics, 65, 48-56.</mixed-citation></ref><ref id="scirp.50301-ref2"><label>2</label><mixed-citation publication-type="other" xlink:type="simple">Pryor, S.G., Lewis, J.E., Weaver, A.L. and Orvidas, L.J. (2005) Pediatric Dermoid Cysts of the Head and Neck. Otolaryngology—Head and Neck Surgery, 132, 938-942.http://dx.doi.org/10.1016/j.otohns.2005.03.005</mixed-citation></ref><ref id="scirp.50301-ref3"><label>3</label><mixed-citation publication-type="other" xlink:type="simple">Adeloye, A. and Odeku, E.L. (1971) Congenital Subgaleal Cysts over the Anterior Fontanelle in Nigerians. Archives of Disease in Childhood, 46, 95-98.</mixed-citation></ref><ref id="scirp.50301-ref4"><label>4</label><mixed-citation publication-type="other" xlink:type="simple">Wong, T.T., Wann, S.L. and Lee, L.S. (1986) Congenital Dermoid Cyst of the Anterior Fontanelle in Chinese Children. Child’s Nervous System, 2, 175-178. http://dx.doi.org/10.1007/BF00706806</mixed-citation></ref><ref id="scirp.50301-ref5"><label>5</label><mixed-citation publication-type="other" xlink:type="simple">Bartlett, S.P., Lin, K.Y., Grossman, R. and Katowitz, J. (1993) The Surgical Management of Orbitofacial Dermoids in the Pediatric Patient. Plastic and Reconstructive Surgery, 91, 1208-1215. http://dx.doi.org/10.1097/00006534-199306000-00005</mixed-citation></ref></ref-list></back></article>