<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article  PUBLIC "-//NLM//DTD Journal Publishing DTD v3.0 20080202//EN" "http://dtd.nlm.nih.gov/publishing/3.0/journalpublishing3.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="3.0" xml:lang="en" article-type="research article"><front><journal-meta><journal-id journal-id-type="publisher-id">SS</journal-id><journal-title-group><journal-title>Surgical Science</journal-title></journal-title-group><issn pub-type="epub">2157-9407</issn><publisher><publisher-name>Scientific Research Publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.4236/ss.2019.104017</article-id><article-id pub-id-type="publisher-id">SS-92199</article-id><article-categories><subj-group subj-group-type="heading"><subject>Articles</subject></subj-group><subj-group subj-group-type="Discipline-v2"><subject>Medicine&amp;Healthcare</subject></subj-group></article-categories><title-group><article-title>
 
 
  Liposarcoma of the Back: Case Report
 
</article-title></title-group><contrib-group><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>A.</surname><given-names>Maïga</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>I.</surname><given-names>Diakité</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>A.</surname><given-names>Bah</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>T.</surname><given-names>Bathio</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>B.</surname><given-names>Diassana</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>A.</surname><given-names>B. Diallo</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>A.</surname><given-names>A. Traoré</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>M.</surname><given-names>Diallo</given-names></name><xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>B.</surname><given-names>T. Dembélé</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Y.</surname><given-names>Sidibé</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>O.</surname><given-names>H. Saadé</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>M.</surname><given-names>Kanté</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>M.</surname><given-names>Konaté</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>S.</surname><given-names>Dembélé</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>M.</surname><given-names>Samaké</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>A.</surname><given-names>Togo</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>A.</surname><given-names>Traoré</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>G.</surname><given-names>Diallo</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib></contrib-group><aff id="aff2"><addr-line>Service of General Surgery, Hospital of Sikasso, Sikasso, Mali</addr-line></aff><aff id="aff1"><addr-line>Service of General Surgery, Teaching Hospital Gabriel Touré, Bamako, Mali</addr-line></aff><aff id="aff3"><addr-line>Reference Heath Center of Commune VI, Bamako, Mali</addr-line></aff><pub-date pub-type="epub"><day>10</day><month>04</month><year>2019</year></pub-date><volume>10</volume><issue>04</issue><fpage>141</fpage><lpage>145</lpage><history><date date-type="received"><day>6,</day>	<month>March</month>	<year>2019</year></date><date date-type="rev-recd"><day>27,</day>	<month>April</month>	<year>2019</year>	</date><date date-type="accepted"><day>30,</day>	<month>April</month>	<year>2019</year></date></history><permissions><copyright-statement>&#169; Copyright  2014 by authors and Scientific Research Publishing Inc. </copyright-statement><copyright-year>2014</copyright-year><license><license-p>This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/</license-p></license></permissions><abstract><p>
 
 
  
    Liposarcoma is a particular form of soft tissue sarcoma. First described by Virchow in 1860, liposarcoma is a rare mesenchymal tumor 
   [1]. It represents 14% to 18% of all malignant tumors of the soft tissues and constitutes the most frequent soft tissue sarcoma 
   [2]. For the majority of authors, it affects adult after the fourth decade. Because of the unusual age, we report a case of largeliposarcoma of the dorsal surface of the trunk. The appearance of the operative part made us think of a possible malignancy. A 35-year-old man without a notable patient history was admitted for a mass of the back discovered three years before without any notion of trauma. The patient affirms the recent appearance of an induration motivating the consultation. There were no associated signs such rectorrhagia, hematemesis, emaciation, pain. The physical examination finds a patient in good general condition. Locally, there is a swelling of the right lateral part of the 1/3 middle part of the back. It is an oval swelling of 25 cm long axis. Any fat tumor having a size more than 5 cm must therefore receive special attention even before the fourth decade. 
  
 
</p></abstract><kwd-group><kwd>Liposarcoma</kwd><kwd> Unusualage</kwd><kwd> Malignancy</kwd></kwd-group></article-meta></front><body><sec id="s1"><title>1. Introduction</title><p>Liposarcomas are generally rare and their incidence does not exceed 2.5 cases/million inhabitants/year [<xref ref-type="bibr" rid="scirp.92199-ref1">1</xref>] . This rarity is relative because liposarcomas still represent 14% to 18% of all malignant tumors of the soft tissues [<xref ref-type="bibr" rid="scirp.92199-ref2">2</xref>] . They are the most common soft tissue sarcomas [<xref ref-type="bibr" rid="scirp.92199-ref3">3</xref>] . They predominate at the level of the limbs (50%) but can also develop at the level of the trunk (33%) [<xref ref-type="bibr" rid="scirp.92199-ref2">2</xref>] . Because of the unusual age, we report a case of large liposarcoma of the dorsal surface of the trunk in a 35-year old patient.</p></sec><sec id="s2"><title>2. Patient and Observation</title><p>A 35-year-old man without a notable patient history was admitted for a mass of the back discovered three years before without any notion of trauma. The patient affirms the recent appearance of an induration motivating the consultation. There were no associated signs such rectorrhagia, hematemesis, emaciation, pain.</p><p>The physical examination finds a patient in good general condition. Locally, there is a swelling of the right lateral part of the 1/3 middle part of the back. It is an oval swelling of 25 cm long axis (<xref ref-type="fig" rid="fig1">Figure 1</xref>, <xref ref-type="fig" rid="fig2">Figure 2</xref>). The surrounding skin looks normal. At palpation the swelling is firm, poorly limited and mobile compared to superficial and deep planes and not painful. The axillary and cervical ganglion areas are free of any adenopathies. The rest of the somatic examination was normal. The chest CT scan (<xref ref-type="fig" rid="fig3">Figure 3</xref>) shows images in favor of a fat mass of the right chest wall of benign shape. The patient underwent tumor excision under general anesthesia. The incision was linear compared to the mass. After opening the fascia and dissecting the fibers of the large dorsal muscle, the tumor was exposed presenting as a fatty mass. Excision of the entire tumor and its capsule is performed (<xref ref-type="fig" rid="fig4">Figure 4</xref>). The continuations were simple with no tumor recurrence to date (18 months).</p><p>The pathological examination of the operative specimen shows a globally lobulated tumor proliferation. The lobules are surrounded by fibrous septa of variable thickness. Within the intra-lobular mature adipocyte plaques, there is the presence of numerous lipoblasts and atypical adipose cells with multi-vacuolar cytoplasm with a nucleolarhyperchromatic nucleus and notch-like appearance. No tumor necrosis was noted and this proliferation is surrounded by a thin fibrous capsule. The diagnosis of well differentiated liposarcoma of sclerosing type was made. The patient was introduced to the multidisciplinary oncology staff.</p></sec><sec id="s3"><title>3. Discussion</title><p>First described by Virchow in 1860, liposarcoma is a rare mesenchymal tumor [<xref ref-type="bibr" rid="scirp.92199-ref1">1</xref>] . However, it is the most common soft tissue sarcoma [<xref ref-type="bibr" rid="scirp.92199-ref3">3</xref>] [<xref ref-type="bibr" rid="scirp.92199-ref4">4</xref>] . It most often affects the adult subject. Some authors find it between 50 and 70 years [<xref ref-type="bibr" rid="scirp.92199-ref2">2</xref>] [<xref ref-type="bibr" rid="scirp.92199-ref5">5</xref>] , others delimits a period of 40 to 60 years [<xref ref-type="bibr" rid="scirp.92199-ref3">3</xref>] , therefore affects the adult after the fourth decade with a male predominance. In our case it’s a young adult of 35 years, what makes the peculiarity. According to some authors, liposarcoma develops at the expense of primitive mesenchymal cells rather than at the expense of adipocytes. It would never develop on a lipoma or pre-existing lipomatosis [<xref ref-type="bibr" rid="scirp.92199-ref3">3</xref>] [<xref ref-type="bibr" rid="scirp.92199-ref5">5</xref>] . Indeed genetic or traumatic factors could promote this differentiation of adipocytes [<xref ref-type="bibr" rid="scirp.92199-ref6">6</xref>] . Clinically, liposarcoma is in the form of a bulky mass generally greater than 5 cm in size. For this purpose several authors report a parallelism between the size of the fat tumors and their malignancy with up to 74% sensitivity of malignancy if the size is greater than 5 cm [<xref ref-type="bibr" rid="scirp.92199-ref7">7</xref>] [<xref ref-type="bibr" rid="scirp.92199-ref8">8</xref>] . This tumoral mass is of variable aspect, most often nodular well limited [<xref ref-type="bibr" rid="scirp.92199-ref1">1</xref>] [<xref ref-type="bibr" rid="scirp.92199-ref3">3</xref>] . The deterioration of the general state and the pains are rare and are found only at the end of evolution [<xref ref-type="bibr" rid="scirp.92199-ref2">2</xref>] . Any fat tumor having a size more than 5 cm must therefore receive special attention even before the fourth decade. Pathologically, there are five types of liposarcoma; well differentiated, myxoid, round cell, pleomorphic, dedifferentiated. Liposarcomas of themyxoid type and of well-differentiated type are the most frequent. [<xref ref-type="bibr" rid="scirp.92199-ref3">3</xref>] [<xref ref-type="bibr" rid="scirp.92199-ref6">6</xref>] [<xref ref-type="bibr" rid="scirp.92199-ref9">9</xref>] [<xref ref-type="bibr" rid="scirp.92199-ref10">10</xref>] . The well-differentiated liposarcomas are tumors of low grade malignancy looking like lipomas hence the name “lipoma like” [<xref ref-type="bibr" rid="scirp.92199-ref2">2</xref>] with the presence of some lipoblasts [<xref ref-type="bibr" rid="scirp.92199-ref3">3</xref>] as shown by the pathological examination of our operative specimen. Whatever histological type, surgical excision is the key to treatment. It may, in some cases be supplemented by radiotherapy and sometimes chemotherapy especially in multiple metastases or inoperable cases. The prognosis of liposarcoma generally depends on the histological type, the size of the tumor and its extent at the time of diagnosis [<xref ref-type="bibr" rid="scirp.92199-ref2">2</xref>] . In all cases, recurrences are frequent and usually occur within 24 months after surgical treatment. Metastases are possible; the most common are pulmonary and hepatic and are haematogenous. However, liposarcoma of well-differentiated type is of better prognosis with a survival rate of more than 50% at 10 years [<xref ref-type="bibr" rid="scirp.92199-ref2">2</xref>] [<xref ref-type="bibr" rid="scirp.92199-ref3">3</xref>] . In addition, adequate initial surgical management combined when indicated with a well-managed adjuvant treatment can reduce recurrences.</p></sec><sec id="s4"><title>4. Conclusion</title><p>Any fat tumor having a size more than 5 cm must therefore receive special attention even before the fourth decade.</p></sec><sec id="s5"><title>The Consent</title><p>We received the patient’s consent.</p></sec><sec id="s6"><title>Conflicts of Interest</title><p>The authors declare no conflicts of interest regarding the publication of this paper.</p></sec><sec id="s7"><title>Cite this paper</title><p>Ma&#239;ga, A., Diakit&#233;, I., Bah, A., Bathio, T., Diassana, B., Diallo, A.B., Traor&#233;, A.A., Diallo, M., Demb&#233;l&#233;, B.T., Sidib&#233;, Y., Saad&#233;, O.H., Kant&#233;, M., Konat&#233;, M., Demb&#233;l&#233;, S., Samak&#233;, M., Togo, A., Traor&#233;, A. and Diallo, G. (2019) Liposarcoma of the Back: Case Report. 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