<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article  PUBLIC "-//NLM//DTD Journal Publishing DTD v3.0 20080202//EN" "http://dtd.nlm.nih.gov/publishing/3.0/journalpublishing3.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="3.0" xml:lang="en" article-type="research article"><front><journal-meta><journal-id journal-id-type="publisher-id">OALibJ</journal-id><journal-title-group><journal-title>Open Access Library Journal</journal-title></journal-title-group><issn pub-type="epub">2333-9705</issn><publisher><publisher-name>Scientific Research Publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.4236/oalib.1104601</article-id><article-id pub-id-type="publisher-id">OALibJ-84572</article-id><article-categories><subj-group subj-group-type="heading"><subject>Articles</subject></subj-group><subj-group subj-group-type="Discipline-v2"><subject>Biomedical&amp;Life Sciences</subject><subject> Business&amp;Economics</subject><subject> Chemistry&amp;Materials Science</subject><subject> Computer Science&amp;Communications</subject><subject> Earth&amp;Environmental Sciences</subject><subject> Engineering</subject><subject> Medicine&amp;Healthcare</subject><subject> Physics&amp;Mathematics</subject><subject> Social Sciences&amp;Humanities</subject></subj-group></article-categories><title-group><article-title>
 
 
  Prevalence and Epidemiology of the Arterial Hypertension of the Adult in Kamina in the Democratic Republic of the Congo
 
</article-title></title-group><contrib-group><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Ilunga</surname><given-names>Masuku Anany</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Banza</surname><given-names>Kyosha Gustave</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Sony</surname><given-names>Namasamba Leaticia</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Kyungu</surname><given-names>Banze Micheline</given-names></name><xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Masengo</surname><given-names>Kazadi Valentin</given-names></name><xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Ilunga</surname><given-names>Mbayo Fiston</given-names></name><xref ref-type="aff" rid="aff4"><sup>4</sup></xref></contrib></contrib-group><aff id="aff4"><addr-line>Faculty of Medicine, University of Malemba-Nkulu, Malemba-Nkulu, Democratic Republic of Congo</addr-line></aff><aff id="aff2"><addr-line>Faculty of Medicine, University of Kamina, Kamina, Democratic Republic of Congo</addr-line></aff><aff id="aff1"><addr-line>Department of Internal Medicine, Kamina Reference General Hospital, Kamina, Democratic Republic of Congo</addr-line></aff><aff id="aff3"><addr-line>Schools of Public Health, University of Kamina, Kamina, Democratic Republic of Congo</addr-line></aff><pub-date pub-type="epub"><day>04</day><month>05</month><year>2018</year></pub-date><volume>05</volume><issue>05</issue><fpage>1</fpage><lpage>9</lpage><history><date date-type="received"><day>15,</day>	<month>April</month>	<year>2018</year></date><date date-type="rev-recd"><day>14,</day>	<month>May</month>	<year>2018</year>	</date><date date-type="accepted"><day>17,</day>	<month>May</month>	<year>2018</year></date></history><permissions><copyright-statement>&#169; Copyright  2014 by authors and Scientific Research Publishing Inc. </copyright-statement><copyright-year>2014</copyright-year><license><license-p>This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/</license-p></license></permissions><abstract><p>
 
 
  High blood pressure (HTA) is a cardiovascular disease more prevalent in consultations in internal medicine; it is until now less controlled in the world, especially in developing countries where the majority of hypertensives are not controlled. In general, it is estimated that hypertension affects between 10% to 15% of the adult population. In some countries the prevalence is slightly higher (about 20% of the adult population) and in some Eastern European countries an even higher prevalence has been observed (up to 30%). This is a cross-sectional descriptive study on the prevalence and epidemiology of HTA in Kamina. The s
  tudy was spread over a 12-month period from January 2017 to December 2017. This study found that out of 222 patients received in internal medicine at the Kamina General Referral Hospital in 2014, 187 subjects represented 84 patients. 2% had different pathologies compared to 35 subjects, 
  i
  .
  e
  . 15.8% had hypertension. We found that participants aged 60 and over are more represented with a workforce of 18% or 51.4% while subjects aged 40-59 represent only a workforce of 5% or 14.3%. As for sex, women are more affected by HTA with a workforce of 21% or 60% while men represent a workforce of 14% or 40%. To better contribute to the reduction of the morbidity and mortality associated with the complications of hypertension, it is necessary to act early upstream according to the extent of this pathology, even at the level of the basic health centers. The significant proportion of severely hypertensive patients requires greater awareness to consult for their follow-up and management.
 
</p></abstract><kwd-group><kwd>Prevalence</kwd><kwd> Epidemiology</kwd><kwd> Arterial Hypertension</kwd></kwd-group></article-meta></front><body><sec id="s1"><title>1. Introduction</title><p>High blood pressure is a more common cardiovascular disease in internal medicine consultations; it is until now less controlled in the world, especially in developing countries where the majority of hypertensives are not controlled [<xref ref-type="bibr" rid="scirp.84572-ref1">1</xref>] .</p><p>In general, it is estimated that hypertension affects between 10% to 15% of the adult population [<xref ref-type="bibr" rid="scirp.84572-ref2">2</xref>] . In some countries the prevalence is slightly higher (about 20% of the adult population) and in some Eastern European countries an even higher prevalence has been observed (up to 30%) [<xref ref-type="bibr" rid="scirp.84572-ref3">3</xref>] . In contrast, in some populations with a developed lifestyle, including some populations in Latin America, Africa and Oceania, the prevalence of hypertension is significantly lower. The data are all based on the conventional maximum pressure of 160/95 mmHg, but using the recently recommended 140/90 mmHg level [<xref ref-type="bibr" rid="scirp.84572-ref2">2</xref>] , the prevalence increases significantly to levels above 30% of adult population.</p><p>Around the world in 2000, the HTA affected about 26.6% for men and 26.1% for women; by the year 2025, it would reach 29.2% of the general population, i.e. 29% of men and 29.5% of women.</p><p>Of the 972 million hypertensive adults, 333 million or 34.3% come from developed countries and 639 million or 65.7% are from developing countries [<xref ref-type="bibr" rid="scirp.84572-ref4">4</xref>] .</p><p>Just under eight million deaths worldwide are thought to be due to hypertension and this is believed to be the cause of stroke and heart disease [<xref ref-type="bibr" rid="scirp.84572-ref5">5</xref>] .</p><p>In Canada, 22.7% of adults over the age of 20 had diagnosed hypertension between 2006-2007. The population aged 60 years and over who took antihypertensive drugs was 46% for women and 38% for men.</p><p>More than four million antihypertensive prescriptions are issued monthly.</p><p>The cost associated with HTA consisting of medical consultation, antihypertensive medications and laboratory tests was $2.3 billion Canadian in 2003 [<xref ref-type="bibr" rid="scirp.84572-ref6">6</xref>] .</p><p>In France, the HTA concerned 10% to 15% of the population, probably fourteen million patients, including eight million treated for a cost of three billion euros [<xref ref-type="bibr" rid="scirp.84572-ref7">7</xref>] .</p><p>The figure tends to increase from 8.6 to 10.5 million people treated as a public health and care problem.</p><p>In sub-Saharan Africa, the proportion for controlled hypertensives does not exceed 5%; despite efforts in the various regions, high blood pressure is a major public health problem [<xref ref-type="bibr" rid="scirp.84572-ref1">1</xref>] .</p><p>In addition, numerous studies conducted around the world have shown that arterial hypertension affects about 15% of the adult population and is responsible for 10% to 20% of all deaths [<xref ref-type="bibr" rid="scirp.84572-ref8">8</xref>] .</p><p>Currently, it is estimated that about 1 billion people worldwide suffer from hypertension and this number is expected to increase with the aging of the population [<xref ref-type="bibr" rid="scirp.84572-ref9">9</xref>] .</p><p>In Africa before the 1930s, cardiovascular diseases and certain chronic diseases such as diabetes and cancer remained non-existent, yet they were a major cause of morbidity and mortality in Europe before the Second World War. Currently, high blood pressure is emerging and together with other cardiovascular diseases will constitute a major public health problem in sub-Saharan Africa by 2020 [<xref ref-type="bibr" rid="scirp.84572-ref10">10</xref>] .</p><p>In fact, the prevalence of arterial hypertension in several African countries varies between 5% and 20% [<xref ref-type="bibr" rid="scirp.84572-ref1">1</xref>] ; in France it was estimated at 11.8% for women and 9.4% for men between July 1994 and June 1995; in the Democratic Republic of Congo (DRC), the HTA reaches more than 30% of adults in the city of Kinshasa. The prevalence of hypertension is even higher in South Kivu, eastern DRC, where it affects 40% of adult subjects [<xref ref-type="bibr" rid="scirp.84572-ref11">11</xref>] .</p><p>The last study on the prevalence and epidemiology of arterial hypertension in Kamina, in health centers, was done in 2008 [<xref ref-type="bibr" rid="scirp.84572-ref12">12</xref>] .</p><p>The present study aims to determine the prevalence and epidemiology of adult arterial hypertension in Kamina.</p></sec><sec id="s2"><title>2. Materials and Method</title><sec id="s2_1"><title>2.1. Place of Study</title><p>The present study was conducted at the Kamina General Reference Hospital (HGR) in the province of Haut-Lomami in the Democratic Republic of the Congo.</p></sec><sec id="s2_2"><title>2.2. Type of Study and Period of Study</title><p>This is a cross-sectional descriptive study on the prevalence and epidemiology of HTA in Kamina. The study spanned a 12-month period from January 2017 to December 2017.</p></sec><sec id="s2_3"><title>2.3. Sample Size</title><p>Our target population is all HAM/KAMINA patients in the internal medicine department during the reporting period, numbering 222. Among them, 35 patients with hypertension arterial hypertension (HTA) constituted our sample. Our sample is therefore exhaustive. Blood pressure was taken from sitting, left arm, 2nd, 5th and 10th minute rest, then the mean was calculated; the tension was taken by one and the same nurse. Has been recognized hypertensive, anyone with a mean Systolic Blood Pressure (PAS) greater than or equal to 140 mmHg and/or a Diastolic Blood Pressure (DBP) greater than or equal to 90 mmHg; or any person already taking one or more antihypertensive medications, so we have taken into account the pre-treatment tension figures, as recorded in their consultation sheet.</p></sec><sec id="s2_4"><title>2.4. Data Management, Collection and Analysis</title><p>The different patient information was collected from individual files or survey forms previously prepared and used as data carriers.</p><p>The collected data were encoded, entered, processed and analyzed using the software Epi info 7. Moreover, the representation of the variables in the form of graphs was carried out by the Excel 2007 software.</p><p>The description of the study population, the epidemiological profile of hypertensive patients, and the prevalence of arterial hypertension were studied.</p></sec><sec id="s2_5"><title>2.5. Inclusion Criterion</title><p>Included in this study were all hypertensive patients who received HGR/kamina in the internal medicine department for whom information was found.</p></sec><sec id="s2_6"><title>2.6. Exclusion Criterion</title><p>In our study, we excluded any patient who presented any pathology other than hypertension and hypertensives whose information was not found.</p></sec><sec id="s2_7"><title>2.7. Ethical Considerations</title><p>While it is true that any study on human beings requires respect for human rights. Our study was spared. all hypertensive patients received information about the purpose of the research. We are reassured of the good understanding and we asked for their consent after the free and informed choice when all the mental faculties are in place. We reassured them about the anonymity and confidentiality of the information.</p></sec></sec><sec id="s3"><title>3. Results</title><sec id="s3_1"><title>3.1. Prevalence of Hypertension</title><p><xref ref-type="fig" rid="fig1">Figure 1</xref> shows that out of 222 patients received in internal medicine at the HGR/Kamina in 2017, 187 subjects or 84.2% had different pathologies compared to 35 cases or 15.8% had hypertension.</p></sec><sec id="s3_2"><title>3.2. Socio-Demographic Characteristics</title><p>The analysis of this <xref ref-type="fig" rid="fig2">Figure 2</xref> presents us with 21 subjects that is 60% coming from Kamina whereas 14 cases or 40% come from outside Kamina.</p><p>With regard to this <xref ref-type="fig" rid="fig3">Figure 3</xref> we find that the participants of 60 years and more are more represented with a staff of 18 is 51.4% whereas the subjects of 40 - 59 years represent only a staff of 5 is 14.3%.</p><p>On <xref ref-type="fig" rid="fig4">Figure 4</xref> we see that women are more affected by HTA with a workforce of 21% or 60% while men represent a workforce of 14% or 40%.</p><p>The analysis of this <xref ref-type="fig" rid="fig5">Figure 5</xref> shows that the hypertensives who were unemployed accounted for 9 cases, or 22.8%, followed by blacksmiths and housework</p><p>with a staff of 6% or 17% against the police who presented a single case, 2.8%.</p><p>In <xref ref-type="fig" rid="fig6">Figure 6</xref> we note that the married are more represented with a staff of 16 is 45.7% while widowers show only 4 cases is 11.4%.</p></sec></sec><sec id="s4"><title>4. Discussion</title><p>We conducted a cross-sectional descriptive study at HGR/KAMINA in the internal medicine department for a 12-month period from January 2017 to December 2017.</p><p>After interpreting the results of our investigations, in this chapter we will try to paraphrase them with those of our few predecessors.</p><sec id="s4_1"><title>4.1. Prevalence of Hypertension</title><p>The prevalence we found in our study is 15.77%, slightly higher than that found at 15% in the global adult population [<xref ref-type="bibr" rid="scirp.84572-ref8">8</xref>] ; as well as that obtained in rural Kinshasa at 14.2% [<xref ref-type="bibr" rid="scirp.84572-ref10">10</xref>] .</p><p>However, it is lower than that determined in 2008 in Kamina, 20% [<xref ref-type="bibr" rid="scirp.84572-ref12">12</xref>] ; 31.1% in Tanzania [<xref ref-type="bibr" rid="scirp.84572-ref13">13</xref>] , 32.5% in Congo Brazzaville in 2004 [<xref ref-type="bibr" rid="scirp.84572-ref14">14</xref>] , 31.0% in France according to the Godet-Thobie study and collaborators in 2006-2007 [<xref ref-type="bibr" rid="scirp.84572-ref15">15</xref>] , 28.6% in the United States in 2003 [<xref ref-type="bibr" rid="scirp.84572-ref16">16</xref>] and 27% to 28% in Sub-Saharan Africa [<xref ref-type="bibr" rid="scirp.84572-ref17">17</xref>] . A larger study across Europe in 2006 found a higher prevalence of 44% in 2006 [<xref ref-type="bibr" rid="scirp.84572-ref18">18</xref>] .</p><p>This aspect is due to the variation of the study environments; this is how we believe that a large scale prospective study could shed light on the true prevalence of hypertension in our environment.</p></sec><sec id="s4_2"><title>4.2. Socio-Demographic Characteristics</title><p>In our study, the age ranges from 18 to 84 years old and the average is 48.69 years old. The most affected age group is 60 years and older, which represents 51.43% of patients. These data are on the one hand close to those reported 2013 in the USA [<xref ref-type="bibr" rid="scirp.84572-ref19">19</xref>] having recorded an age which varies between 18 years and 72 years with an average of 38 years where the subjects of 60 years and more were also more represented with 65, 0%, on the other hand remote from the fact that participants aged 40 to 59 were poorly represented compared to 18 - 39 year olds in our study, which is recognized as the opposite in theirs.</p><p>This would be due to the increase in blood pressure figures with age.</p><p>The distribution by sex gave the female predominance with a sex ratio of 0.67, which was confirmed by the results of the study conducted in 2002 [<xref ref-type="bibr" rid="scirp.84572-ref6">6</xref>] ; Didier Duhot (1995) also proved it with 11.8% among women and 9.4% among men [<xref ref-type="bibr" rid="scirp.84572-ref11">11</xref>] . This female predominance could be explained by the fact that women tend to consult more than men. Finally, women are much more numerous than men, in our country, as in the world. Despite this clear predominance of women in the study population, the frequency of hypertension was still significantly higher among men than women, respectively 34% and 30.6% according to a study conducted in Brazzaville in 2004 [<xref ref-type="bibr" rid="scirp.84572-ref14">14</xref>] ; 34.1% and 27.8% according to a study of the National School Nutrition Health (ENNS) in France in 2006 [<xref ref-type="bibr" rid="scirp.84572-ref15">15</xref>] and finally 47% and 35% according to the Mona Lisa study in France in 2005-2007 [<xref ref-type="bibr" rid="scirp.84572-ref20">20</xref>] . Women would be much more protected against hypertension before menopause [<xref ref-type="bibr" rid="scirp.84572-ref20">20</xref>] .</p><p>The occupational distribution showed a predominance of non-employed participants followed by blacksmiths, housekeepers and chariomans.</p><p>Referring to marital status, our investigations have shown a predominance of married couples.</p></sec></sec><sec id="s5"><title>5. Conclusions</title><p>In Kamina, arterial hypertension is a significant public health problem because of its prevalence, which is significant at 15.77% in the HGR/KAMINA, it affects more women than men, and it is frequent especially in individuals belonging to a remote social rank, unemployed, related to heavy work and toxic habits.</p><p>The prevalence of this pathology increases with age; it is more prevalent among married and divorced people. To better contribute to the reduction of the morbidity and mortality associated with the complications of hypertension, it is necessary to act early upstream according to the extent of this pathology, even at the level of the basic health centers. The significant proportion of severely hypertensive patients requires greater awareness to consult for their follow-up and management.</p></sec><sec id="s6"><title>Cite this paper</title><p>Anany, I.M., Gustave, B.K., Leaticia, S.N., Micheline, K.B., Valentin, M.K. and Fiston, I.M. (2018) Prevalence and Epidemiology of the Arterial Hypertension of the Adult in Kamina in the Democratic Republic of the Congo. Open Access Library Journal, 5: e4601. https://doi.org/10.4236/oalib.1104601</p></sec></body><back><ref-list><title>References</title><ref id="scirp.84572-ref1"><label>1</label><mixed-citation publication-type="other" xlink:type="simple">Unikam, A. (2012) Profil Epidemiologique De L’hta En Milieu Hospitalier Des Cliniques Universitaires De Lubumbashi, VOL. XI, n°2, novembre, 61.</mixed-citation></ref><ref id="scirp.84572-ref2"><label>2</label><mixed-citation publication-type="other" xlink:type="simple">Report of a WHO Expert Committee. Hypertension control. WHO Technical Report Series 862. World Health Organization, Geneva, 1996.</mixed-citation></ref><ref id="scirp.84572-ref3"><label>3</label><mixed-citation publication-type="other" xlink:type="simple">Study on Hypertension control Monitoring at Community Level. WHO Regional Office for Europe, Copenhagen, 1994.</mixed-citation></ref><ref id="scirp.84572-ref4"><label>4</label><mixed-citation publication-type="other" xlink:type="simple">Lawes, C.M., Vander Hoorn, S. and Rodgers, A. (2001) Global Burden of Blood Pressure Related Disease. Lacet, 56.</mixed-citation></ref><ref id="scirp.84572-ref5"><label>5</label><mixed-citation publication-type="other" xlink:type="simple">Agence de la santé publique du canada, Faits et chiffres sur l’HTA, 2009.</mixed-citation></ref><ref id="scirp.84572-ref6"><label>6</label><mixed-citation publication-type="other" xlink:type="simple">Mounier-Vehier, C., Amah, G. and Covillard, J. (2002) Prise en charge de l’HTA essentielle et du niveau de risque cardiovasculaire, Arch Mal c?ur Vaiss. </mixed-citation></ref><ref id="scirp.84572-ref7"><label>7</label><mixed-citation publication-type="other" xlink:type="simple">Recommandations Professionnelles (2007) Suivi et orientation des femmes enceintes en fonction des situations à risque identifiées, Argumentaire; HAS, 23-25, 7-79.</mixed-citation></ref><ref id="scirp.84572-ref8"><label>8</label><mixed-citation publication-type="other" xlink:type="simple">SIPLEY ROD (1965) précis de cardiologie, 2 éd paris, 208.</mixed-citation></ref><ref id="scirp.84572-ref9"><label>9</label><mixed-citation publication-type="journal" xlink:type="simple"><name name-style="western"><surname>Chobanianav</surname><given-names> Bakris</given-names></name>,<name name-style="western"><surname> G.L.</surname><given-names> Black</given-names></name>,<name name-style="western"><surname> H.R.</surname><given-names> et al. </given-names></name>,<etal>et al</etal>. (<year>2003</year>)<article-title>The Seventh Report of Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure; the JNC 7 Report</article-title><source> JAMA</source><volume> 289</volume>,<fpage> 2560</fpage>-<lpage>2572</lpage>.<pub-id pub-id-type="doi"></pub-id></mixed-citation></ref><ref id="scirp.84572-ref10"><label>10</label><mixed-citation publication-type="other" xlink:type="simple">Tony, E.O. (2005) Aspects Epidemiologiques Et Evolutifs De L’accident Vasculaire Cerebral A L’hopital General De Reference De Kinshasa, 2.</mixed-citation></ref><ref id="scirp.84572-ref11"><label>11</label><mixed-citation publication-type="other" xlink:type="simple">Didier Duhot, luc (1995) Enquete Transversale De L’observation De Medecine Generale.</mixed-citation></ref><ref id="scirp.84572-ref12"><label>12</label><mixed-citation publication-type="other" xlink:type="simple">KANONGE MPOYO NORIA (2008) La prévalence de l’hypertension artérielle à l’h?pital général de référence de Kamina, UNIKAM. </mixed-citation></ref><ref id="scirp.84572-ref13"><label>13</label><mixed-citation publication-type="other" xlink:type="simple">Edwards, R., Unwin, N., Mugusi, F., et al. (2000) Hypertension Prevalence and Care in an Urban and Rural Area of Tanzania. Journal of Hypertension, 18, 145-152. https://doi.org/10.1097/00004872-200018020-00003</mixed-citation></ref><ref id="scirp.84572-ref14"><label>14</label><mixed-citation publication-type="other" xlink:type="simple">Kimbally-Kaky, G., Gombet, T., Bolanda, J.D., Voumbo, Y., Okili, B., Ellenga-Mbolla, B., et al. (2006) Prévalence de l’hypertension artérielle à Brazzaville. Cardiologie Tropicale, 32, 43-6.</mixed-citation></ref><ref id="scirp.84572-ref15"><label>15</label><mixed-citation publication-type="other" xlink:type="simple">Godet-Thobie, H., Vernay, M., Noukpoape, A., et al. (2008) Niveau tensionnel moyen et prévalence de l’hypertension artérielle chez les adultes de 18 à 74 ans. Weekly Epidemiological Bulletin, 49-50, 478-482.</mixed-citation></ref><ref id="scirp.84572-ref16"><label>16</label><mixed-citation publication-type="other" xlink:type="simple">Wolf-Maier, K., Cooper, R.S., Banegas, J.R., Giampaoli, S., Hense, H.W., Joffres, M., et al. (2003) Hypertension Prevalence and Blood Pressure Levels in 6 European countries, Canada, and the United States. JAMA, 289, 2363-2369.</mixed-citation></ref><ref id="scirp.84572-ref17"><label>17</label><mixed-citation publication-type="other" xlink:type="simple">Kearney, P.M., Whelton, M., Reynolds, K., et al. (2005) Global Burden of Hypertension: Analysis of Worldwide Data. Lancet, 365, 217-223. https://doi.org/10.1016/S0140-6736(05)70151-3</mixed-citation></ref><ref id="scirp.84572-ref18"><label>18</label><mixed-citation publication-type="other" xlink:type="simple">Hajjar, I., Kotchen, J.M. and Kotchen, T.A. (2006) Hypertension: Trends in Prevalence, Incidence and Control. Annual Review of Public Health, 27, 465-490. https://doi.org/10.1146/annurev.publhealth.27.021405.102132</mixed-citation></ref><ref id="scirp.84572-ref19"><label>19</label><mixed-citation publication-type="other" xlink:type="simple">He, F.J., Li, J. and MacGregor, G.A. (2013) Effect of Longer Term Modest Salt Reduction on Blood Pressure: Cochrane Systematic Review and Meta-Analysis of Randomized Trials. BMJ, 346.</mixed-citation></ref><ref id="scirp.84572-ref20"><label>20</label><mixed-citation publication-type="other" xlink:type="simple">Wagner, A., Arveiler, D., Ruidavets, J.B., et al. (2008) état des lieux sur l’hypertension artérielle en France en 2007: l’étude Mona Lisa. Weekly Epidemiological Bulletin, 49-50, 483-486.</mixed-citation></ref></ref-list></back></article>