Neonatal dermatoses (NND) are mucocutaneous and/or phanerian disorders observed between the 1st and the 28th day of life. They are frequent, diverse and of variable prognosis [1] . They may be transient or constitute true pathologies requiring treatment. It is therefore important to recognize these dermatoses in order to carry out a good evaluation of each case in order to make an appropriate care. Few works have been done on the subject in Africa. The objective of this study is to study the epidemiological and clinical aspects of NND at the NTH-HKM in Cotonou.

This was a cross-sectional descriptive and analytical study that took place from December 1st, 2014 to February 28^th, 2015. All newborns seen in consultation or hospitalized in the Department of Pediatrics and Medical Genetics dermatosis were included. The diagnosis of dermatoses was clinical. After the newborn was examined by a dermatologist, the parents were interviewed and the data supplemented using the newborn's medical record. Any child born before 37 weeks of amenorrhea was considered premature. It is post-term when gestational age was greater than 42 weeks of amenorrhea. Any birth weight greater than or equal to 2500 grams was normal. The data collected were recorded and processed with the EPI INFO software version 3.7. The Chi² test was used to compare the proportions. The threshold of significance was p < 0.05.

Transient neonatal dermatoses: skin manifestations characterized mainly by their spontaneous reversibility, from a few minutes to a few days or weeks.

Pathologic neonatal dermatoses: cutaneous manifestations which do not heal spontaneously during the first month of life and which mostly require treatment.

Several studies have been carried out on the prevalence of NND in different countries and races. The literature reports a prevalence between 40% and 100% [2] [3] . The prevalence of 61.2% in our study is close to that reported by LORENZ S. (59.7%) in Germany [4] . On the other hand, it is less than that obtained by EKIZ Ö. In Turkey (67.3%), KANE A. in Senegal (94.2%), TRAORE A. in Burkina Faso (95%) and OYEDEJE OA in Nigeria 96%) [8] . These different results can be related to study methods (multiplicity of study sites, longer study duration, age of newborns included) and racial characteristics.

The majority (80%) of NNDs were transient as reported by many other authors [5] [6] [8] [9] . This is due to the fact that these dermatoses are phenomena of physiological adaptation to the air environment and linked to intrauterine life. Of these, the most frequent were desquamation + xerosis (33.75%), sweating miliary (22.29%), mongoloid spots (21.36%) and sebaceous hyperplasia (12.38%). These neonatal dermatoses were also the most noted in Senegalese newborns except for the sudoral miliary [6] . The Sahelian-Senegalese climate of Senegal could explain this low rate of sweat miliary observed. KANE A. and FERHABAS A. noted in Senegal and Turkey that desquamation + xerosis was the most frequent dermatosis [6] [10] as we observed (33.75%) at rates of 41%, 43% and 39.5% respectively. These results are in the range of 72% to 83% reported in the literature [11] [12] . In our study, miliary sweat was the second (22.29%) NND

most encountered as in Nigerian newborns (24.6%) [8] . SACHDEVA M. had a rate of 23.8% of sweat miliary in Indian infants [12] , similar to that of our study. On the other hand, TRAORE A. in Burkina Faso had as first neonatal dermatosis the sweat miliary with a rate of 31.1% [7] . This higher rate may be related to climatic conditions and the study period. The rates of mongoloid spot (21.36%) and sebaceous hyperplasia (12.38%) noted in our study are close to those obtained by KANE A. in Senegalese newborns (23.72% for Mongoloid spots and 16.51% for sebaceous hyperplasia) [6] . As for the pathological DNN, the congenital melanocytic nevus came first (40.74%) as in the KANE A. study (39.6%) [6] . The second pathological DNN we noted was the malformations and vascular tumors with a proportion of 18.52%. This rate is close to those of CHAITHIRAYANON S. (16.9%) [13] and FERAHBAS A. (19.2%) [10] .

The majority of the NNDs concerned the glabrous skin in our study as also noted KANE A. [6] . The trunk was the most affected anatomical zone followed by the cephalic part (scalp + face + neck). This is consistent with the results of TRAORE A. in Burkina Faso [7] .

Different studies have been conducted on the correlation between NNDs and some maternal and neonatal factors. In our series, out of the age of newborn babies, no statistically significant relationship could be established with the other factors studied (sex, gestational age, childbirth, birth weight, parity of mothers). TRAORE A, SACHDEVA M and JAIN N [7] [12] [14] also did not find a correlation between the NND factors mentioned above. However, HAVERI FTTS. [15] as well as SHEHAB M. [16] noted that birth weight was statistically associated with NND. This may be due to the difference in the method of study (inclusion and exclusion criteria).

This study allowed us to take stock of the NND at the NTH-HKM given that no data existed on the subject in Benin. It shows us that NNDs are common among newborns at the NTH-HKM. Transient dermatoses were predominant and should be distinguished from pathological dermatoses for possible treatment. Further in-depth investigations, whether or not to specifically link each DNN to particular factors, should be conducted.

No conflicts of interest to declare.

Adegbidi, H., Atadokpede, F., Koudoukpo, C., d’Almeida, M., Dégboé, B., Alihonou, F., Akpadjan, F., Savoeda, L. and do Ango-Padonou, F. (2017) Epidemiological and Clinical Aspects of Neonatal Dermatoses at the National Teaching Hospital HKM of Cotonou Benin. Journal of Cosmetics, Dermatological Sciences and Applications, 7, 204-210. https://doi.org/10.4236/jcdsa.2017.73019