<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article  PUBLIC "-//NLM//DTD Journal Publishing DTD v3.0 20080202//EN" "http://dtd.nlm.nih.gov/publishing/3.0/journalpublishing3.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="3.0" xml:lang="en" article-type="research article"><front><journal-meta><journal-id journal-id-type="publisher-id">OJPed</journal-id><journal-title-group><journal-title>Open Journal of Pediatrics</journal-title></journal-title-group><issn pub-type="epub">2160-8741</issn><publisher><publisher-name>Scientific Research Publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.4236/ojped.2016.62025</article-id><article-id pub-id-type="publisher-id">OJPed-67209</article-id><article-categories><subj-group subj-group-type="heading"><subject>Articles</subject></subj-group><subj-group subj-group-type="Discipline-v2"><subject>Medicine&amp;Healthcare</subject></subj-group></article-categories><title-group><article-title>
 
 
  Glanular Anterior Urethral Valve; A Case Report of an Unusual Cause of Neonatal Urinary Retention
 
</article-title></title-group><contrib-group><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Mohammad</surname><given-names>Aminu Mohammad</given-names></name><xref ref-type="aff" rid="aff1"><sub>1</sub></xref></contrib></contrib-group><aff id="aff1"><label>1</label><addr-line>Bayero University and Aminu Kano Teaching Hospital, Kano, Nigeria</addr-line></aff><author-notes><corresp id="cor1">* E-mail:</corresp></author-notes><pub-date pub-type="epub"><day>20</day><month>05</month><year>2016</year></pub-date><volume>06</volume><issue>02</issue><fpage>171</fpage><lpage>174</lpage><history><date date-type="received"><day>26</day>	<month>April</month>	<year>2016</year></date><date date-type="rev-recd"><day>accepted</day>	<month>5</month>	<year>June</year>	</date><date date-type="accepted"><day>9</day>	<month>June</month>	<year>2016</year></date></history><permissions><copyright-statement>&#169; Copyright  2014 by authors and Scientific Research Publishing Inc. </copyright-statement><copyright-year>2014</copyright-year><license><license-p>This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/</license-p></license></permissions><abstract><p>
 
 
  Anterior urethral valve is an uncommon abnormality whose etiology is uncertain, unlike in the case of posterior urethral valve. Glanular anterior urethral valve is even rarer. We present an unusual case of anterior urethral valve, which presented with acute urinary retention and was successfully managed with excision and glans reconstruction. A history of poor stream and dribbling, recurrent urinary tract infections and palpable penile or peno-scrotal mass strongly points to the diagnosis of anterior urethral valve. A voiding cystourethrogramme confirms the diagnosis. It can cause early proximal urinary tract damage and renal failure if not intervened in time. Early surgical intervention will prevent the onset of uremia. Transurethral resection is the treatment of choice.
 
</p></abstract><kwd-group><kwd>Glanular</kwd><kwd> Anterior Urethral Valve</kwd><kwd> Urinary Retention</kwd></kwd-group></article-meta></front><body><sec id="s1"><title>1. Introduction</title><p>Urethral valves are congenital anomalies that affect the urethra below the bladder neck commonly seen in boys. Posterior Urethral Valve (PUV) is the most prevalent; these are sail like valves that are found in the posterior urethra just below the verumontanum. Anterior Urethral Valves (AUV) are quite rare [<xref ref-type="bibr" rid="scirp.67209-ref1">1</xref>] - [<xref ref-type="bibr" rid="scirp.67209-ref3">3</xref>] . The recognition and the original report on anterior urethral valves is attributed to Williams in 1958 and, since then, several cases have been described, both separately and in association with proximal urethral diverticula [<xref ref-type="bibr" rid="scirp.67209-ref1">1</xref>] [<xref ref-type="bibr" rid="scirp.67209-ref2">2</xref>] . Association of the two is extremely rare and only four cases have been reported [<xref ref-type="bibr" rid="scirp.67209-ref2">2</xref>] .</p><p>Anterior urethral valves are more common in the bulbar urethra (40%) and equally occur in penile urethra and penoscrotal junction (30%). Some cases were described at the navicular fossa, and often mistaken for urethral meatal stenosis [<xref ref-type="bibr" rid="scirp.67209-ref1">1</xref>] . Glanular anterior urethral valves are the least common.</p><p>This report describes a case of glanular anterior urethral valve, emphasizing its clinical and therapeutic aspects.</p><p>Case report</p><p>The child was delivered at 36 weeks of gestation and was immediately noted to have swollen distal part of the penis. He was subsequently noted to have difficulty passing urine which only came in drops. With bulging of glanular urethra, the mother had prenatal ultrasonograpy and no fetal anomaly was reported. This baby presented at the age of 16 days. His chief complains were dribbling of turbid urine, bulging of the distal part of the penis and intermittent high grade fever. He had antibiotic therapy from the first week of life (<xref ref-type="fig" rid="fig1">Figure 1</xref>).</p><p>Patient was evaluated with ultrasound which showed thickened urinary bladder and moderate hydro ureters with normal renal function. He had catheterization, parenteral antibiotics (oral amoxicillin 50 mg/kg and later parenteral ceftriaxone 50 mg/kg) and had excision of the diverticulum and glanuloplasty. He did well post surgery and repeat renal function assessment remained normal with adequate urinary stream. At three month of post excision, there was no episode urosepsis or lower urinary tract symptoms (<xref ref-type="fig" rid="fig2">Figure 2</xref> and <xref ref-type="fig" rid="fig3">Figure 3</xref>).</p><fig id="fig1"  position="float"><label><xref ref-type="fig" rid="fig1">Figure 1</xref></label><caption><title> Anterior urethral valve showing bulging glanular urethra</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/4-1330500x6.png"/></fig><fig id="fig2"  position="float"><label><xref ref-type="fig" rid="fig2">Figure 2</xref></label><caption><title> Opened dilated glanular urethra</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/4-1330500x7.png"/></fig><fig id="fig3"  position="float"><label><xref ref-type="fig" rid="fig3">Figure 3</xref></label><caption><title> Early post operative outcome</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/4-1330500x8.png"/></fig></sec><sec id="s2"><title>2. Discussion</title><p>Anterior urethral valve is an uncommon abnormality whose etiology is uncertain, unlike in the case of posterior urethral valve. Various suggestions as its cause have been forwarded, which include incomplete fusion of the urethral plate, an attempt at urethral duplication and incomplete focal development of the corpus spongiosum [<xref ref-type="bibr" rid="scirp.67209-ref1">1</xref>] . AUV can be located anywhere distal to the membranous urethra [<xref ref-type="bibr" rid="scirp.67209-ref2">2</xref>] . Glanular anterior urethral valve is very rare as in this case report. This might be explained by failure of focal development of the distal part of the corpus spongiosum which differentiates into the glans penis which leads to hypoplasia and dilatation of the glans and glanular urethra leading to pooling of urine and terminal dribbling and recurrent urinary tract infection.</p><p>The signs and symptoms of urinary obstruction are the commonest; poor urinary stream and/or terminal dribbling occur in about 40% of the patients. Serious obstruction concomitantly with hydronephrosis and renal impairment may occur in newborns and infants. Another common sign in distal urethral obstruction due to anterior urethral valve is the bulging of the penile urethra caused by the filling and distension of the urethral diverticulum on straining during urination and sometimes even at rest due to poor emptying of the diverticulum. In severe bladder outflow obstruction, there is concomitant occurrence of bladder distension making it easily palpable [<xref ref-type="bibr" rid="scirp.67209-ref1">1</xref>] - [<xref ref-type="bibr" rid="scirp.67209-ref6">6</xref>] . There are basically two main types of anterior urethral valves distinguished by the presence of absence of diverticulum [<xref ref-type="bibr" rid="scirp.67209-ref7">7</xref>] [<xref ref-type="bibr" rid="scirp.67209-ref8">8</xref>] .</p><p>The diagnosis of these lesions is mainly clinical, however, maturating cystourethrogramme would reveal the diverticulum while abdominal ultrasonograpy will demonstrate the back pressure effects on the urinary bladder, ureters and kidneys. Blood chemistry will demonstrate presence or absence of renal impairment. Therefore early diagnosis and prompt treatment of these patients will reduce incidence of renal failure.</p><p>There are various treatment methods such as open ure-throtomy and excision of the valve, segmental urethrectomy of the valve-bearing area along with a primary end-to-end anastomosis, cold disruption and transurethral resection of the valve. But endoscopic valve ablation by electrocautery has been the procedure of choice [<xref ref-type="bibr" rid="scirp.67209-ref2">2</xref>] .<sup> </sup></p><p>In this case the endoscopic resection diagnosis or resection was not feasible due to lack of appropriate sized cystoscope/resectoscope for our patient’s urethra. Vesicostomy is recommended in infants with high grade reflux and poor emptying of the urinary tract. If the urethra is of sufficient caliber and support, transurethral fulguration is recommended. Open urethroplasty is useful in patients with a large urethral diverticulum and thin urethra [<xref ref-type="bibr" rid="scirp.67209-ref8">8</xref>] .</p><p>Both parents consented to the publication of this case report and I have no complicit of interest or source of funding to declare.</p></sec><sec id="s3"><title>Cite this paper</title><p>Mohammad Aminu Mohammad, (2016) Glanular Anterior Urethral Valve; A Case Report of an Unusual Cause of Neonatal Urinary Retention. Open Journal of Pediatrics,06,171-174. doi: 10.4236/ojped.2016.62025</p></sec></body><back><ref-list><title>References</title><ref id="scirp.67209-ref1"><label>1</label><mixed-citation publication-type="other" xlink:type="simple">Tucci Jr., S., Franco, P.B., Molina, C.A.F., Suaid, H.J., Cologna, A.J. and Martins, A.C.P. (2003) Anterior Urethral Valves. 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