<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article  PUBLIC "-//NLM//DTD Journal Publishing DTD v3.0 20080202//EN" "http://dtd.nlm.nih.gov/publishing/3.0/journalpublishing3.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="3.0" xml:lang="en" article-type="research article"><front><journal-meta><journal-id journal-id-type="publisher-id">JEP</journal-id><journal-title-group><journal-title>Journal of Environmental Protection</journal-title></journal-title-group><issn pub-type="epub">2152-2197</issn><publisher><publisher-name>Scientific Research Publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.4236/jep.2016.76078</article-id><article-id pub-id-type="publisher-id">JEP-66551</article-id><article-categories><subj-group subj-group-type="heading"><subject>Articles</subject></subj-group><subj-group subj-group-type="Discipline-v2"><subject>Earth&amp;Environmental Sciences</subject></subj-group></article-categories><title-group><article-title>
 
 
  A Comparison of Relative Humidity between Two Swedish Buildings with Different Ventilation Solutions
 
</article-title></title-group><contrib-group><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>homas</surname><given-names>Alsmo</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Catharina</surname><given-names>Alsmo</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib></contrib-group><aff id="aff1"><addr-line>Library Research, Olten, Switzerland</addr-line></aff><pub-date pub-type="epub"><day>11</day><month>05</month><year>2016</year></pub-date><volume>07</volume><issue>06</issue><fpage>855</fpage><lpage>873</lpage><history><date date-type="received"><day>24</day>	<month>February</month>	<year>2016</year></date><date date-type="rev-recd"><day>accepted</day>	<month>16</month>	<year>May</year>	</date><date date-type="accepted"><day>19</day>	<month>May</month>	<year>2016</year></date></history><permissions><copyright-statement>&#169; Copyright  2014 by authors and Scientific Research Publishing Inc. </copyright-statement><copyright-year>2014</copyright-year><license><license-p>This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/</license-p></license></permissions><abstract><p>
 
 
   This project is based on measurements of the parameter relative humidity, RH (%), in two buildings: one with natural ventilation and one with mechanical ventilation. Both buildings are located in central Sweden, which constitutes a representative climate zone with respect to Swedish conditions. An important factor for the indoor environment, which affects human health and well-being, is the level of the relative humidity, RH (%). Research studies show that the healthiest level should be in the range of 40% - 60%. Surveys have revealed that about 70% of the employees at Swedish offices, schools and kindergartens experience that the air is too dry during the winter season. Previous studies show that the level of relative humidity in the indoor environment influences the prevalence of respiratory infections and allergies. The purpose of this study is to investigate how the relative humidity differ between the two buildings, and if this may be a cause of the health problems that users are affected by. During many years, users have complained about the environment in the building with mechanical ventilation and that they suffer from health problems. The method used in the study is air measurements of the two parameters, relative humidity and air temperature in the two buildings using data loggers. The indoor environment is affected by the outdoor climate and therefore instruments are placed outdoors to record seasonal variations. The measurements were carried out during the period October 2014 to September 2015 to include all of Sweden’s four seasons with completely different climatic conditions. The results of this study show that the relative humidity in the mechanically ventilated building is consistently significantly lower than in the building with natural ventilation whatever the time of year and temperature indoors. This study shows that mechanical ventilation in buildings affects the indoor environment negatively with respect to human health during most time of the year and this fact must be taken into consideration for the existing as well as the planning of new ventilation systems.
     
 
</p></abstract><kwd-group><kwd>Hygiene</kwd><kwd> Hygiene and Health</kwd><kwd> Air Quality</kwd><kwd> Sick Building Syndrome (SBS)</kwd><kwd> Particle Implication</kwd><kwd> Particle Measurements</kwd><kwd> Indoor Environment; Indoor Humidity</kwd><kwd> Indoor Temperature</kwd><kwd> Particle Size</kwd><kwd> Particle Amount</kwd><kwd> Physical Environment</kwd></kwd-group></article-meta></front><body><sec id="s1"><title>1. Introduction</title><p>This project is based on measurements of the parameter relative humidity, RH (%), in an office building. During many years, users have complained about the conditions in the indoor environment in the building and that they suffer from health problems. These health problems are considered to be related to deficiencies in the building’s technological status. The relationship between the parties involved is in many situations difficult with differing views on how to handle the situation and the measures to be taken. Extensive investigations have been conducted and as well public health facilities, at both regional and local levels, as experts with extensive experience in this type of problem have been engaged. Despite this, no unified plan has been developed for a chance to resolve the problems. In autumn 2013, the property owner launched an action program within the framework of the Swedish authorities’ directives about how this type of project should be handled. With regard to this, it has still been difficult to continue to pursue the matter. Among the users, there are those who regularly stay in the concerned premises and experience severe health problems. In addition to these effects, there is concern in the workplace. The property owner’s proposed measures to correct the deficiencies have not been taken into account by those who represent the users.</p><p>An important factor for the quality of the indoor environment, which affects human health and well-being, is the level of relative humidity, RH (%). Studies have shown that about 70% of the employees at Swedish offices, schools and kindergartens feel that the indoor air is too dry during the winter season [<xref ref-type="bibr" rid="scirp.66551-ref1">1</xref>] . Studies show that the level of relative humidity in the indoor environment influences the prevalence of respiratory infections and allergies. These studies show that the key factors for a healthy indoor air environment are:</p><p>1) to limit the number of the airborne particles since they are carriers of both bacteria, viruses, and allergen;</p><p>2) the relative humidity is at a level above 40% and below 70%, which has the effect that the survival of viruses and bacteria is minimized [<xref ref-type="bibr" rid="scirp.66551-ref2">2</xref>] .</p><p>A survey focused on those directly involved in the office building, reveals that 72% of the employees experience that the indoor air is too dry during the winter months. The corresponding figure for the summer months is 40% [<xref ref-type="bibr" rid="scirp.66551-ref3">3</xref>] .</p></sec><sec id="s2"><title>2. Humidity and Health Impacts</title><p>The requirement for a “suitable thermal climate” is a commonly formulated functional requirement and what temperature that can be accepted must be assessed for each situation. A normal level of indoor air temperature in Sweden should be at least 20˚C so that the total comfort indoor climate should be considered acceptable. Disorders and discomforts of cooling cannot be assessed solely by measurements of air temperature, since the perceived temperature will depend on several factors. Those climatic factors are in addition to air temperature, radiant temperature, air velocity and humidity. High indoor temperatures correlate with both the outdoor climate and the construction of the building, but also the heat that the activity itself generates. In offices, lighting and computer equipment are normally the operational heat sources that create the largest increment of heat. The high moisture content of the air in the summer makes it even more difficult to get rid of excess body heat. Buildings with a light body, low room height, small rooms and poorly insulated roof structures and with large windows without shading and air vents places in the sun, causes the temperature to rise quickly indoors. Unpleasant solar radiation through windows can be limited with various types of solar shading [<xref ref-type="bibr" rid="scirp.66551-ref4">4</xref>] .</p><p>The humidity is a measure of the amount or proportion of water vapor that the air contains. It can be specified as either:</p><p>・ absolute humidity, where the actual amount of water vapor is indicated, or as</p><p>・ relative humidity, where the proportion of water vapor are relative to the maximum possible amount of water vapor at a certain temperature, known as the saturation vapor content, see <xref ref-type="fig" rid="fig1">Figure 1</xref>.</p><p>In this project we study the relative humidity, RH (%). In epidemiological studies, the researchers have examined the relationship between the number of respiratory infections and the relative humidity in offices, homes and schools. The incidence of respiratory infections were found to be lower among people who work or live in environments with a relative humidity level between 40% and 70%, in comparison with those who live in environments with a relative humidity level below or above this level. An overview of the relative humidity shows that the negative health effects can be minimized by maintaining a relative humidity of 40% and below 60%. The effect of relative humidity, with respect to biological and chemical factors, is graphically summarized in <xref ref-type="fig" rid="fig2">Figure 2</xref>. The shape and height of the bars in <xref ref-type="fig" rid="fig2">Figure 2</xref> indicate an increase or a decrease in power and provides no quantitative data. Most of the illustrated negative health effects increase in severity over 60% and/or below 40% relative humidity. The exceptions are the chemical interactions that consistently increase over 30%, and the conditions that produce ozone, which is constantly increasing in severity with a drop in relative humidity. A reduction in morbidity and possibly mortality from influenza is an important factor for increasing the relative humidity from low to middle [<xref ref-type="bibr" rid="scirp.66551-ref2">2</xref>] . Within the framework of this project, a literature review was conducted. The results of this review demonstrate the substantial health problems in both too high and too low relative humidity</p><fig id="fig1"  position="float"><label><xref ref-type="fig" rid="fig1">Figure 1</xref></label><caption><title> The graph shows the relationship between the saturation vapor content (g/m<sup>3</sup>) and temperature (˚C). It should be pointed out that the air generally contains a certain limited amount of water and at lower temperature the water content is further gradually reduced, see the graph in the diagram</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/10-6702932x6.png"/></fig><fig id="fig2"  position="float"><label><xref ref-type="fig" rid="fig2">Figure 2</xref></label><caption><title> The effect of relative humidity, on biological and chemical factors, is graphically summarized above. The optimum zone is in the range between 40% - 60% relative humidity to minimize the negative health effects of common air pollutants [<xref ref-type="bibr" rid="scirp.66551-ref2">2</xref>] </title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/10-6702932x7.png"/></fig><p>indoors [<xref ref-type="bibr" rid="scirp.66551-ref5">5</xref>] - [<xref ref-type="bibr" rid="scirp.66551-ref38">38</xref>] .</p><p>The relative humidity may vary very much over the day and the indoor air is perceived to be dry when it is below 30%. Dry air tends to be more common in colder climates because the air cannot hold the moisture and it folds out (condenses) [<xref ref-type="bibr" rid="scirp.66551-ref39">39</xref>] . Regarding the relative humidity in indoor environments, the range for normal indoor temperatures of 19˚C - 27˚C, there are both direct and indirect effects that affect health and comfort. There may be physical discomfort at both low and high relative humidity [<xref ref-type="bibr" rid="scirp.66551-ref40">40</xref>] . Extremely low levels, below 20%, may cause eye irritation [<xref ref-type="bibr" rid="scirp.66551-ref41">41</xref>] [<xref ref-type="bibr" rid="scirp.66551-ref42">42</xref>] , while moderate or high levels of humidity have been shown to reduce the degree of difficulty for people with asthma [<xref ref-type="bibr" rid="scirp.66551-ref43">43</xref>] . Several reports indicate that:</p><p>・ patients are bothered by dryness of the nose and throat where low relative humidity prevails and that</p><p>・ the relative humidity indoors should be maintained above 30% - 40% to prevent drying of the mucous membranes and to maintain adequate nasal mucus transport and ciliary activity [<xref ref-type="bibr" rid="scirp.66551-ref44">44</xref>] - [<xref ref-type="bibr" rid="scirp.66551-ref50">50</xref>] .</p><p>The relative humidity also has an important direct negative effect on health when high humidity is combined with high temperatures. This combination reduces the rate of evaporative cooling of the body and can cause significant discomfort or lead to heat exhaustion, fatigue and possibly death. Diseases are transmitted either by airborne pathogens, direct contact with pathogens that live on hard surfaces such as furniture and fittings or by touching an infected person. Low relative humidity has been shown to enhance the survival of rhinoviruses and influenza viruses [<xref ref-type="bibr" rid="scirp.66551-ref51">51</xref>] and human rotavirus (a cause of gastroenteritis) on hard surfaces [<xref ref-type="bibr" rid="scirp.66551-ref52">52</xref>] . Experimental studies on the survival of pathogens in the air with different relative humidity rate and epidemiological studies of respiratory infections, suggest that the relative humidity indoors affect the incidence of infectious diseases transmitted by airborne pathogens. Rapid evaporation in dry air can cause the diameter of some aerosols to reduce below the size limit for a particle to remain in suspension*, while at higher relative humidity, the same aerosol reach the floor before sufficient evaporation occurs [<xref ref-type="bibr" rid="scirp.66551-ref53">53</xref>] [<xref ref-type="bibr" rid="scirp.66551-ref54">54</xref>] . An increase in the amount of suspended aerosols, as a result of relatively low humidity is more likely to have an effect on health than the reduction of these during periods of very high relative humidity. Experimental studies have shown that the relative humidity is an important factor for the survival of airborne pathogens and affects the survival by altering the integrity of the cell wall or the viral cover [<xref ref-type="bibr" rid="scirp.66551-ref55">55</xref>] .</p><disp-formula id="scirp.66551-formula51"><graphic  xlink:href="http://html.scirp.org/file/10-6702932x8.png"  xlink:type="simple"/></disp-formula></sec><sec id="s3"><title>3. Measurements</title><p>All measurements of humidity assume that there is an upper limit to the humidity, which depends on temperature and pressure. If you then either add more water vapor (moisture) or lower the gas temperature, the amount of water vapor eventually exceed this maximum and the excess precipitates as water droplets = condensation, see <xref ref-type="fig" rid="fig1">Figure 1</xref>. The instruments used in this study are the Testo 175, data logger, which has two channels for each relative humidity and air temperature with internal and external sensor connection. The stored measured values are evaluated by software and both programming and reading of the instrument is made to the computer via a USB connection. This study includes measurements of relative humidity, RH (%) and air temperature, ˚C for two types of buildings, one with mechanical ventilation and one with a natural ventilation design. In the mechanically ventilated building people have for many years complained about the indoor environment. The measurements were carried out at seven locations in the mechanically ventilated building, where two representative measuring sites are presented in this report. In the building with natural ventilation, measurements were taken at three sites, including one representative test site in this report. Both buildings are located in central Sweden as a representative climate zone for Swedish conditions. The purpose of the study is to examine, compare and evaluate if any difference can be identified regarding the relative humidity in these two buildings as a result of various ventilation solutions. The measurement period covers the period from October 8th, 2014 to September 24th, 2015, which includes all the seasonal variations that occur in Sweden. The measurement instruments have continuously collected data with a frequency of every two hours. The total number of measured values for the period is 4200 pieces per measurement site and parameter. The climate outdoors is the basis of the status of the indoor environment and therefore measurements are also carried out in the outside air that surrounds each affected building.</p><p>From previous measurements in school buildings, the results show that the relative humidity is affected by the building’s ventilation system. From a health aspect the mechanically ventilated buildings are significantly unhealthier for the users than buildings with natural ventilation systems, see <xref ref-type="fig" rid="fig3">Figure 3</xref>. In the building with natural</p><fig id="fig3"  position="float"><label><xref ref-type="fig" rid="fig3">Figure 3</xref></label><caption><title> The graph shows the relative humidity, RH (%) in 12 buildings, 6 with mechanically ventilated systems and 6 with natural draft. The buildings, one of each category, are distributed at locations in Sweden that includes the different climate zones with the following test sites: 1) South Gotaland; 2) East Svealand; 3) West Svealand; 4) South Norrland; 5) North East Norrland; 6) North West Norrland. The measurement period runs from 10-24 January 2014, a winter period and the diagram shows the average values as well as the highest and lowest measured values for each building. The results clearly show that the relative humidity, RH (%) in mechanically ventilated systems in all cases is lower than in the corresponding case for natural ventilation systems [<xref ref-type="bibr" rid="scirp.66551-ref56">56</xref>] </title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/10-6702932x9.png"/></fig><p>ventilation the humidity level rises during the day when there’re activities in the building. Compared with a similar situation in mechanically ventilated buildings, it happens that the level even further decline during the daytime, see <xref ref-type="fig" rid="fig4">Figure 4</xref> and <xref ref-type="fig" rid="fig5">Figure 5</xref> [<xref ref-type="bibr" rid="scirp.66551-ref56">56</xref>] . Calculations of average values of relative humidity regarding public health are in this context misleading.</p><p>・ In buildings with natural ventilation systems the humidity level is higher when people are staying there;</p><p>・ In mechanically ventilated buildings the humidity level is lower when there are people in the building.</p><p>Here we have identified a problem. The relative humidity during the day should be higher in mechanically ventilated buildings due to human presence, than during the night when there is no one in the building. However, as shown in <xref ref-type="fig" rid="fig4">Figure 4</xref> and <xref ref-type="fig" rid="fig5">Figure 5</xref>, the humidity level drops in buildings with mechanical ventilation when the activities start. The only explanation for this is that the ventilation flow was increased from substantially reduced flow rates up to 100% efficiency.</p></sec><sec id="s4"><title>4. Results</title><p>Generally, there was a fairly mild winter season 2014/2015 with a continuous period of freezing temperatures from the end of November/December to mid-March. For a few days at the end of December 2014, there was a strong cold spell. The measurements show that the temperature outdoors permanently increases from February until the summer period June to August, when the temperature level is more stable around 20˚C. The relative humidity outdoors is stably higher than 80% during the winter period, until the end of February and then more frequently fluctuate between 20% and 100%. At the end of the measurement period, in September 2015, the level is more regularly over 60%. The results from the measurements outdoors, see <xref ref-type="fig" rid="fig6">Figure 6</xref>. The graphs in Figures 7-18 report humidity levels indoors and regarding the indoor temperature there are small variations over shorter periods. This is likely caused by various temporary changes in the indoor environment and climate change, outdoor, temperature variations, influence of the sun etc. Regarding the air temperature in the buildings, it is at the levels expected prevailing in this type of environment. The measurement results indoors show that</p><fig id="fig4"  position="float"><label><xref ref-type="fig" rid="fig4">Figure 4</xref></label><caption><title> Measurement results of humidity, RH (%), for the measurement period January 10 to 24 2014 in the buildings in <xref ref-type="fig" rid="fig3">Figure 3</xref>, at measuring location 4, southern Norrland, in one of the buildings with mechanical ventilation and in one of the buildings with natural ventilation. The graphs show that humidity varies during the day when there’s activity going on in the buildings. When the classroom is staffed the relative humidity, RH (%), raises with the natural ventilation system, while this effect is not achieved in the classroom with the mechanical system where the air instead further dries out. The only explanation for this is that the ventilation flow was increased from 0 or from reduced flow to 100% efficiency [<xref ref-type="bibr" rid="scirp.66551-ref56">56</xref>] </title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/10-6702932x10.png"/></fig><fig id="fig5"  position="float"><label><xref ref-type="fig" rid="fig5">Figure 5</xref></label><caption><title> Measurement results of humidity, RH (%), in the same buildings as in <xref ref-type="fig" rid="fig3">Figure 3</xref>, one morning during the period January 10 to 24, 2014. The graphs show that the humidity is different during daytime, the same way as in <xref ref-type="fig" rid="fig4">Figure 4</xref>. In natural ventilation buildings the level raised, unlike the situation in the mechanically ventilated buildings where the level fell further. There is activity in both buildings during the day, which should add humidity to the air, but instead as shown by the black dots in the diagrams, the level decreases in these buildings. The only explanation for this is that the ventilation flow was increased from 0 or from reduced flows to 100% efficiency [<xref ref-type="bibr" rid="scirp.66551-ref56">56</xref>] </title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/10-6702932x11.png"/></fig><fig id="fig6"  position="float"><label><xref ref-type="fig" rid="fig6">Figure 6</xref></label><caption><title> The relative humidity, RH (%) and the outdoor temperature for the period 8 October 2014-24 September 2015, at a site in central Sweden</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/10-6702932x12.png"/></fig><fig id="fig7"  position="float"><label><xref ref-type="fig" rid="fig7">Figure 7</xref></label><caption><title> The relative humidity, RH (%), and temperature in the building with mechanical ventilation for the period 8 October 2014-24 September 2015. The building is located in central Sweden</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/10-6702932x13.png"/></fig><fig id="fig8"  position="float"><label><xref ref-type="fig" rid="fig8">Figure 8</xref></label><caption><title> The relative humidity, RH (%) and temperature in the building with mechanical ventilation for the period from October 8 to December 31 in 2014. The building is located in central Sweden</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/10-6702932x14.png"/></fig><fig id="fig9"  position="float"><label><xref ref-type="fig" rid="fig9">Figure 9</xref></label><caption><title> The relative humidity, RH (&amp;) and the temperature in the building with mechanical ventilation for the period January 1 to May 31, 2015. The building is located in central Sweden</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/10-6702932x15.png"/></fig><fig id="fig10"  position="float"><label><xref ref-type="fig" rid="fig1">Figure 1</xref>0</label><caption><title> The relative humidity, RH (%) and temperature in the building with mechanical ventilation for the period June 1 to September 4, 2015. The building is located in central Sweden</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/10-6702932x16.png"/></fig><fig id="fig11"  position="float"><label><xref ref-type="fig" rid="fig1">Figure 1</xref>1</label><caption><title> The relative humidity, RH (%) and temperature in the building with mechanical ventilation for the period from 8 October 2014-24 September 2015. The building is located in central Sweden</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/10-6702932x17.png"/></fig><fig id="fig12"  position="float"><label><xref ref-type="fig" rid="fig1">Figure 1</xref>2</label><caption><title> The relative humidity, RH (%) and temperature in the building with mechanical ventilation for the period from October 8 to December 31, 2014. The building is located in central Sweden</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/10-6702932x18.png"/></fig><fig id="fig13"  position="float"><label><xref ref-type="fig" rid="fig1">Figure 1</xref>3</label><caption><title> The relative humidity, RH (%) and temperature in the building with mechanical ventilation for the period January 1 to May 31, 2015. The building is located in central Sweden</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/10-6702932x19.png"/></fig><fig id="fig14"  position="float"><label><xref ref-type="fig" rid="fig1">Figure 1</xref>4</label><caption><title> The relative humidity, RH (%) and temperature in the building with mechanical ventilation for the period 1 June- September 22 2015. The building is located in central Sweden</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/10-6702932x20.png"/></fig><fig id="fig15"  position="float"><label><xref ref-type="fig" rid="fig1">Figure 1</xref>5</label><caption><title> The relative humidity, RH (%) and temperature in the building with natural ventilation for the period from 8 October 2014-24 September 2015. The building is located in central Sweden</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/10-6702932x21.png"/></fig><fig id="fig16"  position="float"><label><xref ref-type="fig" rid="fig1">Figure 1</xref>6</label><caption><title> The relative humidity, RH (%) and temperature in the building with natural ventilation for the period from October 8 to December 31, 2014. The building is located in central Sweden</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/10-6702932x22.png"/></fig><fig id="fig17"  position="float"><label><xref ref-type="fig" rid="fig1">Figure 1</xref>7</label><caption><title> The relative humidity, RH (%) and temperature in the building with natural ventilation for the period January 1 to May 31, 2015. The building is located in central Sweden</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/10-6702932x23.png"/></fig><fig id="fig18"  position="float"><label><xref ref-type="fig" rid="fig1">Figure 1</xref>8</label><caption><title> The relative humidity, RH (%) and temperature in the building with natural ventilation for the period January 1 to May 31, 2015. The building is located in central Sweden</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/10-6702932x24.png"/></fig><table-wrap id="table1" ><label><xref ref-type="table" rid="table1">Table 1</xref></label><caption><title> The table below shows the average, maximum and minimum values of the relative humidity measured for the entire measurement period (A) and for three different periods (B - D)</title></caption><table><tbody><thead><tr><th align="center" valign="middle" >BUILDING</th><th align="center" valign="middle"  colspan="3"  >MECHANICAL VENTILATION</th><th align="center" valign="middle"  colspan="3"  >NATURAL VENTILATION</th></tr></thead><tr><td align="center" valign="middle" >Period</td><td align="center" valign="middle" >Average</td><td align="center" valign="middle" >Maximum</td><td align="center" valign="middle" >Minimum</td><td align="center" valign="middle" >Average</td><td align="center" valign="middle" >Maximum</td><td align="center" valign="middle" >Minimum</td></tr><tr><td align="center" valign="middle" >A: 8 Oct 2014 - 24 Sep 2015</td><td align="center" valign="middle" >29.25</td><td align="center" valign="middle" >65.50</td><td align="center" valign="middle" >7.30</td><td align="center" valign="middle" >40.30</td><td align="center" valign="middle" >72.80</td><td align="center" valign="middle" >24.30</td></tr><tr><td align="center" valign="middle" >B: 8 Oct - 31 Dec 2014</td><td align="center" valign="middle" >28.58</td><td align="center" valign="middle" >54.40</td><td align="center" valign="middle" >7.30</td><td align="center" valign="middle" >39.74</td><td align="center" valign="middle" >57.10</td><td align="center" valign="middle" >24.70</td></tr><tr><td align="center" valign="middle" >C: 1 Jan - 31 May 2015</td><td align="center" valign="middle" >20.78</td><td align="center" valign="middle" >40.70</td><td align="center" valign="middle" >9.50</td><td align="center" valign="middle" >33.32</td><td align="center" valign="middle" >56.50</td><td align="center" valign="middle" >24.30</td></tr><tr><td align="center" valign="middle" >D: 1 June - 24 Sep 2015</td><td align="center" valign="middle" >42.31</td><td align="center" valign="middle" >65.50</td><td align="center" valign="middle" >18.90</td><td align="center" valign="middle" >51.05</td><td align="center" valign="middle" >72.80</td><td align="center" valign="middle" >33.40</td></tr></tbody></table></table-wrap><table-wrap id="table2" ><label><xref ref-type="table" rid="table2">Table 2</xref></label><caption><title> The table below is a summary regarding the difference in the relative humidity level, RH (%) in time between the two ventilation systems, with RH lower than 40%</title></caption><table><tbody><thead><tr><th align="center" valign="middle" >BUILDING</th><th align="center" valign="middle" >MECHANICAL VENTILATION</th><th align="center" valign="middle" >NATURAL VENTILATION</th><th align="center" valign="middle" >DIFFERENCE IN TIME</th></tr></thead><tr><td align="center" valign="middle" >RH below 40%</td><td align="center" valign="middle" >7.0 months</td><td align="center" valign="middle" >5.0 months</td><td align="center" valign="middle" >2.0 months (17% of time)</td></tr><tr><td align="center" valign="middle" >RH below 30%</td><td align="center" valign="middle" >7.0 months</td><td align="center" valign="middle" >1.5 months</td><td align="center" valign="middle" >5.5 months (46% of time)</td></tr><tr><td align="center" valign="middle" >RH below 20%</td><td align="center" valign="middle" >5.0 months</td><td align="center" valign="middle" >0.0 months</td><td align="center" valign="middle" >5.0 months (42% of time)</td></tr></tbody></table></table-wrap><p>there is generally lower relative humidity, RH (%), in the mechanically ventilated building than in the building with natural ventilation. <xref ref-type="table" rid="table1">Table 1</xref> and <xref ref-type="table" rid="table2">Table 2</xref> show the average, maximum and minimum values of the relative humidity measured for the entire measurement period (A) and for three different periods (B - D). With regard to the previously described in Chapter 2, the relative humidity levels are low in the mechanically ventilated building and the figures in the table indicate a distinct difference from the building with a natural ventilation system.</p><p>・ Average value: In the building with the mechanically ventilated system the average level of the relative humidity, RH, is for the entire performance period = 29.25%, that is, lower than 30%, see line A. If we study the periods B and C, the relative humidity is 28.58% and 20.78% in two of the three periods, that is, lower than 30%. Only during the period D, June 1th to September 24th, the average exceeds 40% (42.31%). For the naturally ventilated building the average level of relative humidity doesn’t drop below 30% in any of the measuring periods. For the entire measurement period, the level’s for period A 40.30%, B 39.74%, C 33.32% and for period D 52.05%.</p><p>・ Minimum level: The lowest measured level of the relative humidity is below 10% in the mechanically ventilated building during two periods (B and C). Even during the summer and autumn, a period of limited heating in buildings and moisture-rich air outdoors, the RH level is below 20% (18.90%). For the building with natural ventilation the level is at no point below 20%, and is not less than 24.30% during the three periods A - C and 33% for the period D.</p><p>As illustrated by the graphs in Figures 7-22 the measurement results show that there is generally low relative humidity indoors.</p><p>1) Relative humidity below 40% is an indication that health problems can affect people, see Chapter 2. This level is crossed regularly in the beginning of October in the building with the mechanically ventilated system and is constantly below this level until the middle of June. That is, this negative situation for the indoor environment continues for seven months. There after the level is kept more frequently above 40%, see <xref ref-type="fig" rid="fig7">Figure 7</xref> and <xref ref-type="fig" rid="fig1">Figure 1</xref>1. For the building with the natural ventilation system the RH level below 40% is passed in mid-November and being re-stabilized above 40% in May. That is, this situation is going on for five months, see <xref ref-type="fig" rid="fig1">Figure 1</xref>5.</p><p>2) In the mechanically ventilated system the RH level is more regularly below 30% in mid-November. Compared with the natural ventilation system, where this occurs only at the end of December. In order to re-obtain a more stable level, that is a RH level of 30%, this does not occur until the middle of June for the mechanically ventilated building. The corresponding ratio for the natural ventilation system takes place in mid-February. The level of relative humidity, RH &lt; 30%, continues for seven months in the building with the mechanically ventilated system compared with 1.5 months in the natural ventilated building. This is a powerful indicator and the period of time that separates the two buildings is about as much as 5.5 months or 46% of the season.</p><fig id="fig19"  position="float"><label><xref ref-type="fig" rid="fig1">Figure 1</xref>9</label><caption><title> Comparison of the relative humidity, RH (%) in two buildings, one with mechanical ventilation and the other with natural draft for the period from 8 October 2014-24 September 2015. The buildings are located in central Sweden</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/10-6702932x25.png"/></fig><fig id="fig20"  position="float"><label><xref ref-type="fig" rid="fig2">Figure 2</xref>0</label><caption><title> Comparison of the relative humidity, RH (%) in two buildings, one with mechanical ventilation and the other with a natural draft for the period from 8 October-31 December 2014. The buildings are located in central Sweden</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/10-6702932x26.png"/></fig><fig id="fig21"  position="float"><label><xref ref-type="fig" rid="fig2">Figure 2</xref>1</label><caption><title> Comparison of the relative humidity, RH (%) in two buildings, one with mechanical ventilation and the other with natural draft for the period 1 January-31 May 2015. The buildings are located in central Sweden</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/10-6702932x27.png"/></fig><fig id="fig22"  position="float"><label><xref ref-type="fig" rid="fig2">Figure 2</xref>2</label><caption><title> Comparison of the relative humidity, RH (%) in two buildings, one with mechanical ventilation and the other with natural draft for the period 1 June-24 September 2015. The buildings are located in central Sweden</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/10-6702932x28.png"/></fig><p>3) Lower relative humidity than 20% occurs at the end of November in the building with the mechanical ventilated system, while in the building with natural ventilation system the relative humidity at no time falls below this level. The mechanical system obtains once a more stable RH level of 20% at the end of April/May. Here’s a significant difference identified between the two different ventilation solutions. During five months, that is 42% of the season, the RH level is more regularly above 20% with a lowest level of 10% with the mechanical ventilation system. Regarding the natural ventilated building the RH level is never below 20%, but is the lowest 24.30%.</p><p>One example is the Swedish requirement that the carbon dioxide level indoors only during short periods is allowed to exceed 1000 ppm, which creates big problems. Local authorities require that the carbon dioxide level of 1000 ppm may not be exceeded and treats it as a legal requirement, even though it represents only an indicator of ventilation. Ventilation systems are in fact designed to not exceed this level. When more people than before will be housed in the premises, thus increased air flows are required which then causes the air to further dry out that and even lower RH levels are created. When problems arise for users concerning the indoor environment, it is common that the authorities immediately draws attention to the ventilation system and require increased airflows. If the building has a natural ventilation system, it is highly likely that the authority submits to the property owner to install a mechanical ventilation system with flows based on the parameter of carbon dioxide with a maximum permitted level of 1000 ppm. [<xref ref-type="bibr" rid="scirp.66551-ref57">57</xref>] . Survey Studies show that 72% of the employees feel that the air is too dry during the winter months, while the corresponding figure for the summer period is 40% [<xref ref-type="bibr" rid="scirp.66551-ref3">3</xref>] . This study shows that the perceived situation can be supported by physical measurements of the current environment. The results indicate that mechanical ventilation in buildings affects the indoor environment negatively with respect to human health during most time of the year.</p></sec><sec id="s5"><title>5. Conclusion</title><p>The conclusions of the study show that mechanical ventilation, with respect to human health, has a negative impact on the indoor environment during much of the year. The results are illustrative and given what is described in Chapter 2 and in <xref ref-type="fig" rid="fig2">Figure 2</xref>, it is an important issue to clarify how human health is affected by staying for longer periods and during much of the day in environments with these various conditions. The situation is even more pronounced during the winter months and it is documented that the incidence of respiratory infections increases in the winter when people are exposed to long periods of low RH level indoors [<xref ref-type="bibr" rid="scirp.66551-ref2">2</xref>] [<xref ref-type="bibr" rid="scirp.66551-ref16">16</xref>] [<xref ref-type="bibr" rid="scirp.66551-ref19">19</xref>] [<xref ref-type="bibr" rid="scirp.66551-ref58">58</xref>] - [<xref ref-type="bibr" rid="scirp.66551-ref63">63</xref>] . However, given the link between RH level and health disorders, the conclusion is that the low RH levels prevailing in today’s buildings must be taken into consideration and given the right conditions. The situation regarding the level of relative humidity must be highlighted and addressed in an entirely different way than what is happening today. Escalating complaints about health problems due to staying in a particular indoor environment and the problem known as the “Sick-Building” problem are constantly discussed in today’s modern society (see what is described on the website of the Work Environment Authority theme page, sick buildings) [<xref ref-type="bibr" rid="scirp.66551-ref64">64</xref>] . Despite these statements, and that the problem situation only seems to increase, the authorities and others don’t consider the parameter relative humidity from a health perspective. The mechanically ventilated system creates, from a health perspective, a very low relative humidity, and this fact must be taken into consideration for the existing systems as well as the planning of new ventilation systems. It is necessary in view of the Swedish climate conditions that henceforth, consider the relative humidity in calculations and installation of ventilation systems. An important national issue to come to terms with the dry indoor air is the authority requirement for ventilation flows. This requirement is based on maintaining a carbon dioxide level that only rarely exceeds 1000 ppm [<xref ref-type="bibr" rid="scirp.66551-ref57">57</xref>] which governs the ventilation design. This situation dilutes the negative effect on the relative humidity and further dries out the indoor air. This requirement must be questioned as it has been shown that it is based on inadequately substantiated materials from the authorities [<xref ref-type="bibr" rid="scirp.66551-ref65">65</xref>] [<xref ref-type="bibr" rid="scirp.66551-ref66">66</xref>] and where the corresponding level in the EU is 5000 ppm [<xref ref-type="bibr" rid="scirp.66551-ref67">67</xref>] . For direct health effects the level of carbon dioxide has to be significantly higher, for example first at a 30-minute exposure at 50,000 ppm produces signs of intoxication [<xref ref-type="bibr" rid="scirp.66551-ref68">68</xref>] .</p></sec><sec id="s6"><title>Cite this paper</title><p>Thomas Alsmo,Catharina Alsmo, (2016) A Comparison of Relative Humidity between Two Swedish Buildings with Different Ventilation Solutions. Journal of Environmental Protection,07,855-873. doi: 10.4236/jep.2016.76078</p></sec></body><back><ref-list><title>References</title><ref id="scirp.66551-ref1"><label>1</label><mixed-citation publication-type="other" xlink:type="simple">Alsmo, C. and Alsmo, T. (2013) A Study of Hygiene in Swedish Schools and Pre-Schools-Sources of Air Pollution. Journal of Environmental Protection, 4, 1349-1359.</mixed-citation></ref><ref id="scirp.66551-ref2"><label>2</label><mixed-citation publication-type="journal" xlink:type="simple"><name name-style="western"><surname>Arundel</surname><given-names> A.V.</given-names></name>,<name name-style="western"><surname> Sterling</surname><given-names> E.M.</given-names></name>,<name name-style="western"><surname> Biggin J.H. and Sterling</surname><given-names> T.D. </given-names></name>,<etal>et al</etal>. (<year>1986</year>)<article-title>Indirect Health Effects of Relative Humidity in Indoor Environments</article-title><source> Environmental Health Perspectives</source><volume> 65</volume>,<fpage> 351</fpage>-<lpage>356</lpage>.<pub-id pub-id-type="doi"></pub-id></mixed-citation></ref><ref id="scirp.66551-ref3"><label>3</label><mixed-citation publication-type="other" xlink:type="simple">(2014) Myc-Tech AB, the Town Hall, Falu Municipality, Social Care Administrations. Survey Report 2014-11-25, info@myctech.com.</mixed-citation></ref><ref id="scirp.66551-ref4"><label>4</label><mixed-citation publication-type="other" xlink:type="simple">(2011) Public Health Agency of Sweden and the Swedish Work Environment Authority. &lt;br /&gt;http://www.folkhalsomyndigheten.se/amnesomraden/halsoskydd-och-miljohalsa/inomhusmiljo/temperatur/ &lt;br /&gt;https://www.av.se/inomhusmiljo/temperatur-och-klimat/ &lt;br /&gt;https://www.av.se/globalassets/filer/publikationer/foreskrifter/engelska/occupational-exposure-limit-values-provisions-afs2011-18.pdf</mixed-citation></ref><ref id="scirp.66551-ref5"><label>5</label><mixed-citation publication-type="book" xlink:type="simple">La Force, F.M. (1984) Airborne Infections and Modern Building Technology. In: Berglund, B., Lindvall, T. and Sundell, J., Eds., Proceedings of the 3rd International Conference on Indoor Air Quality and Climate 1: Recent Advances in the Health Sciences and Technology, Swedish Council for Building Research, Stockholm, 109-127.</mixed-citation></ref><ref id="scirp.66551-ref6"><label>6</label><mixed-citation publication-type="other" xlink:type="simple">Fitzgerald, J.W. (1975) Approximation Formulas for the Equilibrium Size of an Aerosol Particle as a Function of Its Dry Size and Composition and the Relative Humidity. Journal of Applied Meteorology, 14, 1044-1049.&lt;br /&gt;http://dx.doi.org/10.1175/1520-0450(1975)014&lt;1044:AFFTES&gt;2.0.CO;2</mixed-citation></ref><ref id="scirp.66551-ref7"><label>7</label><mixed-citation publication-type="other" xlink:type="simple">Wright, D.N., Bailey, G.D. and Hutch, M.J. (1968) Survival of Airborne Mycoplasma as Affected by Relative Humidity. Journal of Bacteriology, 95, 251-252.</mixed-citation></ref><ref id="scirp.66551-ref8"><label>8</label><mixed-citation publication-type="other" xlink:type="simple">Flynn, D.D. and Goldberg, L.J. (1971) Effect of Relative Humidity on Aerosol Persistence of Streptococcus salivarius. Archives of Environmental Health, 23, 40-42. &lt;br /&gt;http://dx.doi.org/10.1080/00039896.1971.10665952</mixed-citation></ref><ref id="scirp.66551-ref9"><label>9</label><mixed-citation publication-type="other" xlink:type="simple">Anderson, J.D., Dark, E.A. and Pbto, S. (1968) The Effect of Aerosolization upon Survival and Potassium Retention by Various Bacteria. Journal of General Microbiology, 52, 99-105. &lt;br /&gt;http://dx.doi.org/10.1099/00221287-52-1-99</mixed-citation></ref><ref id="scirp.66551-ref10"><label>10</label><mixed-citation publication-type="other" xlink:type="simple">Rosebury, T. (1947) Experimental Airborne Infection. Williams and Wilkins, Baltimore.</mixed-citation></ref><ref id="scirp.66551-ref11"><label>11</label><mixed-citation publication-type="other" xlink:type="simple">Webb, S.J. (1959) Factors Affecting the Viability of Airborne Bacteria. 1: Bacteria Aerosolized from Distilled Water. Canadian Journal of Microbiology, 5, 649-669. &lt;br /&gt;http://dx.doi.org/10.1139/m59-079</mixed-citation></ref><ref id="scirp.66551-ref12"><label>12</label><mixed-citation publication-type="journal" xlink:type="simple"><name name-style="western"><surname>Couch</surname><given-names> R.B. </given-names></name>,<etal>et al</etal>. (<year>1981</year>)<article-title>Viruses and Indoor Air Pollution</article-title><source> Bulletin of the New York Academy of Medicine</source><volume> 57</volume>,<fpage> 907</fpage>-<lpage>921</lpage>.<pub-id pub-id-type="doi"></pub-id></mixed-citation></ref><ref id="scirp.66551-ref13"><label>13</label><mixed-citation publication-type="other" xlink:type="simple">Langmuir, A.D. (1980) Changing Concepts of Airborne Infection of Acute Contagious Diseases: A Reconsideration of Classic Epidemiologic Theories. Annals of the New York Academy of Sciences, 353, 35-44. &lt;br /&gt;http://dx.doi.org/10.1111/j.1749-6632.1980.tb18903.x</mixed-citation></ref><ref id="scirp.66551-ref14"><label>14</label><mixed-citation publication-type="other" xlink:type="simple">Moffet, H.L. (1980) Clinical Microbiology. J. B. Lippincott, Philadelphia.</mixed-citation></ref><ref id="scirp.66551-ref15"><label>15</label><mixed-citation publication-type="other" xlink:type="simple">Gwaltney, J.M. (1980) Epidemiology of the Common Cold. Annals of the New York Academy of Sciences, 353, 54-60.&lt;br /&gt;http://dx.doi.org/10.1111/j.1749-6632.1980.tb18905.x</mixed-citation></ref><ref id="scirp.66551-ref16"><label>16</label><mixed-citation publication-type="other" xlink:type="simple">Knight, V. (1980) Viruses as Agents of Airborne Contamination. Annals of the New York Academy of Sciences, 353, 147-156. &lt;br /&gt;http://dx.doi.org/10.1111/j.1749-6632.1980.tb18917.x</mixed-citation></ref><ref id="scirp.66551-ref17"><label>17</label><mixed-citation publication-type="other" xlink:type="simple">Miller, W.S. and Artenstein, M.S. (1967) Aerosol Stability of Three Acute Respiratory Disease Viruses. Experimental Biology and Medicine, 125, 222-227. &lt;br /&gt;http://dx.doi.org/10.3181/00379727-125-32054</mixed-citation></ref><ref id="scirp.66551-ref18"><label>18</label><mixed-citation publication-type="other" xlink:type="simple">Davis, G.W., Griesemer, R.A., Shadduck, J.A. and Farrell, R.L. (1971) Effect of Relative Humidity on Dynamic Aerosols of Adenovirus 12. Journal of Applied Microbiology, 21, 676-679.</mixed-citation></ref><ref id="scirp.66551-ref19"><label>19</label><mixed-citation publication-type="other" xlink:type="simple">Hemmes, J.H., Winkler, K.C. and Kool, S.M. (1960) Virus Survival as a Seasonal Factor in Influenza and Poliomyelitis. Nature, 188, 430-431. &lt;br /&gt;http://dx.doi.org/10.1038/188430a0</mixed-citation></ref><ref id="scirp.66551-ref20"><label>20</label><mixed-citation publication-type="other" xlink:type="simple">Harper, G.J. (1961) Airborne Micro-Organisms: Survival Tests with Four Viruses. Journal of Hygiene, 59, 479-486.&lt;br /&gt;http://dx.doi.org/10.1017/S0022172400039176</mixed-citation></ref><ref id="scirp.66551-ref21"><label>21</label><mixed-citation publication-type="other" xlink:type="simple">Schulman, J.L. and Kilbourne, E.D. (1962) Airborne Transmission of Influenza Virus Infection in Mice. Nature, 195, 1129-1130. &lt;br /&gt;http://dx.doi.org/10.1038/1951129a0</mixed-citation></ref><ref id="scirp.66551-ref22"><label>22</label><mixed-citation publication-type="other" xlink:type="simple">Lester Jr., W. (1948) The Influence of Relative Humidity on the Infectivity of Air-Borne Influenza a Virus (PR8- Strain). Journal of Experimental Medicine, 88, 361-367. &lt;br /&gt;http://dx.doi.org/10.1084/jem.88.3.361</mixed-citation></ref><ref id="scirp.66551-ref23"><label>23</label><mixed-citation publication-type="other" xlink:type="simple">Schaffer, E.L., Soergel, M.E. and Straube, D.C. (1976) Survival of Airborne Influenza Virus, Effects of Propagating Host, Relative Humidity, and Composition of Spray Fluids. Archives of Virology, 51, 263-273.&lt;br /&gt;http://dx.doi.org/10.1007/BF01317930</mixed-citation></ref><ref id="scirp.66551-ref24"><label>24</label><mixed-citation publication-type="other" xlink:type="simple">Wraith, D.G., Cunnington, A.M. and Seymour, W.M. (1979) The Role and Allergenic Importance of Storage Mites in House Dust and Other Environments. Clinical &amp; Experimental Allergy, 9, 545-561. &lt;br /&gt;http://dx.doi.org/10.1111/j.1365-2222.1979.tb00478.x</mixed-citation></ref><ref id="scirp.66551-ref25"><label>25</label><mixed-citation publication-type="journal" xlink:type="simple"><name name-style="western"><surname>Korsgaard</surname><given-names> J. </given-names></name>,<etal>et al</etal>. (<year>1982</year>)<article-title>Preventive Measures in House Dust Allergy</article-title><source> American Review of Respiratory Disease</source><volume> 125</volume>,<fpage> 80</fpage>-<lpage> 84</lpage>.<pub-id pub-id-type="doi"></pub-id></mixed-citation></ref><ref id="scirp.66551-ref26"><label>26</label><mixed-citation publication-type="other" xlink:type="simple">Arlian, L.G., Bernstein, I.L. and Gallagher, J.S. (1982) The Prevalence of House Dust Mites, Dermatophagoides spp, and Associated Environmental Conditions in Homes in Ohio. Journal of Allergy and Clinical Immunology, 69, 527- 532. &lt;br /&gt;http://dx.doi.org/10.1016/0091-6749(82)90178-6</mixed-citation></ref><ref id="scirp.66551-ref27"><label>27</label><mixed-citation publication-type="other" xlink:type="simple">Murray, A.B. and Zuk, P. (1979) The Seasonal Variation in a Population of House Dust Mites in a North American City. Journal of Allergy and Clinical Immunology, 64, 266-269. &lt;br /&gt;http://dx.doi.org/10.1016/0091-6749(79)90142-8</mixed-citation></ref><ref id="scirp.66551-ref28"><label>28</label><mixed-citation publication-type="other" xlink:type="simple">Arlan, L.G., Brandt, R.L. and Bernstein, R. (1978) Occurrence of House Dust Mites, Dermatophagoides spp. (Acari: Pyroglyphidae), during the Heating Season. Journal of Medical Entomology, 15, 35-42. &lt;br /&gt;http://dx.doi.org/10.1093/jmedent/15.1.35</mixed-citation></ref><ref id="scirp.66551-ref29"><label>29</label><mixed-citation publication-type="other" xlink:type="simple">Gravesen, S. (1979) Fungi as a Cause of Allergic Disease. Allergy, 34, 135-154. &lt;br /&gt;http://dx.doi.org/10.1111/j.1398-9995.1979.tb01562.x</mixed-citation></ref><ref id="scirp.66551-ref30"><label>30</label><mixed-citation publication-type="other" xlink:type="simple">English, P.T. (1980) Medical Mycology. Edward Arnold, London.</mixed-citation></ref><ref id="scirp.66551-ref31"><label>31</label><mixed-citation publication-type="other" xlink:type="simple">NAS (National Academy of Sciences) (1981) Indoor Pollutants. National Academy Press, Washington DC.</mixed-citation></ref><ref id="scirp.66551-ref32"><label>32</label><mixed-citation publication-type="other" xlink:type="simple">Andersen, I., Lundqvist, G.R. and Molhave, L. (1976) The Effect of Air Humidity and Sulphur Dioxide on Formaldehyde Emissions from a Construction Material (Chipboard). Holzforschung und Holzverwertung, 28, 120-121.</mixed-citation></ref><ref id="scirp.66551-ref33"><label>33</label><mixed-citation publication-type="other" xlink:type="simple">IEC Beak Consultants Ltd. (1983) Indoor Air Quality, Cambridge Sealed Homes: A Report for Ontario Ministry of Municipal Affairs and Housing. IEC Beak, Mississauga, Ontario.</mixed-citation></ref><ref id="scirp.66551-ref34"><label>34</label><mixed-citation publication-type="other" xlink:type="simple">Sheppard, D., Wong, W.S. and Uehora, C.F. (1981) Lower Threshold and Greater Bronchomotor Responsiveness of Asthmatic Subjects to Sulfur Dioxide. American Review of Respiratory Disease, 122, 873-878.</mixed-citation></ref><ref id="scirp.66551-ref35"><label>35</label><mixed-citation publication-type="other" xlink:type="simple">Alaire, Y., Ulrich, C.E., Busey, W.M., Krumma, A.A. and MacFarland, H.N. (1972) Long-Term Continuous Exposures to SO2 in Cynomolgus Monkey. Archives of Environmental Health: An International Journal, 24, 115-128. &lt;br /&gt;http://dx.doi.org/10.1080/00039896.1972.10666060</mixed-citation></ref><ref id="scirp.66551-ref36"><label>36</label><mixed-citation publication-type="other" xlink:type="simple">US Environmental Protection Agency (1982) Air Quality Criteria for Oxides of Nitrogen. Environmental Criteria and Assessment Office, Research Triangle Park, NC.</mixed-citation></ref><ref id="scirp.66551-ref37"><label>37</label><mixed-citation publication-type="other" xlink:type="simple">Mueller, F., Loeb, L. and Maper, W.H. (1973) Decomposition Rates of Ozone in Living Areas. Environmental Science &amp; Technology, 7, 342-346. &lt;br /&gt;http://dx.doi.org/10.1021/es60076a003</mixed-citation></ref><ref id="scirp.66551-ref38"><label>38</label><mixed-citation publication-type="other" xlink:type="simple">Farrell, B.R., Kerr, H.D. and Kulle, T.J. (1979) Adaptation in Human Subjects to the Effects of Inhaled Ozone after Repeated Exposure. American Review of Respiratory Disease, 119, 725-730.</mixed-citation></ref><ref id="scirp.66551-ref39"><label>39</label><mixed-citation publication-type="other" xlink:type="simple">Wikipedia. &lt;br /&gt;https://en.wikipedia.org/wiki/Relative_humidity</mixed-citation></ref><ref id="scirp.66551-ref40"><label>40</label><mixed-citation publication-type="other" xlink:type="simple">Meyer, B. (1983) Indoor Air Quality. Addison-Wesley, Reading.</mixed-citation></ref><ref id="scirp.66551-ref41"><label>41</label><mixed-citation publication-type="other" xlink:type="simple">McIntyre, D.A. (1978) Response to Atmospheric Humidity at Comfortable Air Temperature: A Comparison of Three Experiments. Annals of Occupational Hygiene, 21, 177-190. &lt;br /&gt;http://dx.doi.org/10.1093/annhyg/21.2.177</mixed-citation></ref><ref id="scirp.66551-ref42"><label>42</label><mixed-citation publication-type="other" xlink:type="simple">Eng, W.G. (1979) Survey on Eye Comfort in Aircraft: 1. Flight Attendants. Aviation, Space, and Environmental Medicine, 50, 401-404.</mixed-citation></ref><ref id="scirp.66551-ref43"><label>43</label><mixed-citation publication-type="other" xlink:type="simple">Strauss, R.H., McFadden, E.R., Ingram, R.H., Deal, E.C. and Jaeger, J. (1978) Influence of Heat and Humidity on the Airway Obstruction Induced by Exercise in Asthma. Journal of Clinical Investigation, 61, 433-440.&lt;br /&gt;http://dx.doi.org/10.1172/JCI108954</mixed-citation></ref><ref id="scirp.66551-ref44"><label>44</label><mixed-citation publication-type="journal" xlink:type="simple"><name name-style="western"><surname>Lubart</surname><given-names> J. </given-names></name>,<etal>et al</etal>. (<year>1962</year>)<article-title>The Common Cold and Humidity Imbalance</article-title><source> New York State Journal of Medicine</source><volume> 62</volume>,<fpage> 817</fpage>-<lpage>819</lpage>.<pub-id pub-id-type="doi"></pub-id></mixed-citation></ref><ref id="scirp.66551-ref45"><label>45</label><mixed-citation publication-type="other" xlink:type="simple">Lubart, J. (1979) Health Care Containment Cost. American Journal of Otolaryngology, 1, 81-83.&lt;br /&gt;http://dx.doi.org/10.1016/S0196-0709(79)80011-3</mixed-citation></ref><ref id="scirp.66551-ref46"><label>46</label><mixed-citation publication-type="journal" xlink:type="simple"><name name-style="western"><surname>Zeterberg</surname><given-names> J.M. </given-names></name>,<etal>et al</etal>. (<year>1973</year>)<article-title>A Review of Respiratory Virology and the Spread of Virulent and Possibly Antigenic Viruses via Air Conditioning Systems</article-title><source> Annals of Allergy</source><volume> 31</volume>,<fpage> 228</fpage>-<lpage>234</lpage>.<pub-id pub-id-type="doi"></pub-id></mixed-citation></ref><ref id="scirp.66551-ref47"><label>47</label><mixed-citation publication-type="journal" xlink:type="simple"><name name-style="western"><surname>Sale</surname><given-names> C.S. </given-names></name>,<etal>et al</etal>. (<year>1971</year>)<article-title>Humidification during the Cold Weather to Assist Perennial Allergic Rhinitis Patients</article-title><source> Annals of Allergy</source><volume> 29</volume>,<fpage> 356</fpage>-<lpage>357</lpage>.<pub-id pub-id-type="doi"></pub-id></mixed-citation></ref><ref id="scirp.66551-ref48"><label>48</label><mixed-citation publication-type="journal" xlink:type="simple"><name name-style="western"><surname>Ingelstedt</surname><given-names> S. </given-names></name>,<etal>et al</etal>. (<year>1956</year>)<article-title>Studies on the Conditioning of Air in the Respiratory Tract</article-title><source> Acta Oto-Laryngologica</source><volume> 131</volume>,<fpage> 1</fpage>-<lpage>80</lpage>.<pub-id pub-id-type="doi"></pub-id></mixed-citation></ref><ref id="scirp.66551-ref49"><label>49</label><mixed-citation publication-type="other" xlink:type="simple">Drettner, B., Falck, B. and Simon, H. (1977) Measurements of the Air Conditioning Capacity of the Nose during Normal and Pathological Conditions and Pharmacological Influence. Acta Oto-Laryngologica, 84, 266-277.&lt;br /&gt;http://dx.doi.org/10.3109/00016487709123966</mixed-citation></ref><ref id="scirp.66551-ref50"><label>50</label><mixed-citation publication-type="journal" xlink:type="simple"><name name-style="western"><surname>Richards</surname><given-names> J.H. </given-names></name>,<etal>et al</etal>. (<year>1974</year>)<article-title>Effect of Relative Humidity on the Rheologic Properties of Bronchial Mucus</article-title><source> American Review of Respiratory Disease</source><volume> 109</volume>,<fpage> 484</fpage>-<lpage>486</lpage>.<pub-id pub-id-type="doi"></pub-id></mixed-citation></ref><ref id="scirp.66551-ref51"><label>51</label><mixed-citation publication-type="other" xlink:type="simple">Buckland, E.E. and Tyrrell, D.A.J. (1962) Loss of Infectivity on Drying Various Viruses. Nature, 195, 1063-1064.&lt;br /&gt;http://dx.doi.org/10.1038/1951063a0</mixed-citation></ref><ref id="scirp.66551-ref52"><label>52</label><mixed-citation publication-type="other" xlink:type="simple">Moe, K. and Shirley, J.A. (1982) The Effect of Relative Humidity and Temperature on the Survival of Human Rotavirus in Faeces. Archives of Virology, 72, 179-186. &lt;br /&gt;http://dx.doi.org/10.1007/BF01348963</mixed-citation></ref><ref id="scirp.66551-ref53"><label>53</label><mixed-citation publication-type="journal" xlink:type="simple"><name name-style="western"><surname>Smith</surname><given-names> E.B. </given-names></name>,<etal>et al</etal>. (<year>1983</year>)<article-title>Atmospheric Factors Affecting Transmission of Infections</article-title><source> Practitioner (UK)</source><volume> 227</volume>,<fpage> 1667</fpage>-<lpage>1677</lpage>.<pub-id pub-id-type="doi"></pub-id></mixed-citation></ref><ref id="scirp.66551-ref54"><label>54</label><mixed-citation publication-type="other" xlink:type="simple">Hanel, G. (1977) Humidity Effects on Gravitational Settling and Brownian Diffusion of Atmospheric Particles. Pure and Applied Geophysics, 115, 775-797. &lt;br /&gt;http://dx.doi.org/10.1007/BF00881210</mixed-citation></ref><ref id="scirp.66551-ref55"><label>55</label><mixed-citation publication-type="book" xlink:type="simple">Hatch, M.T. and Wolochow, H. (1969) Bacterial Survival, Consequences of the Airborne State. In: Dimmick, R.L. and Akers, A.B., Eds., An Introduction to Experimental Aero Biology, John Wiley and Sons Inc., New York.</mixed-citation></ref><ref id="scirp.66551-ref56"><label>56</label><mixed-citation publication-type="other" xlink:type="simple">Alsmo, T. and Alsmo, C. (2014) Ventilation and Relative Humidity in Swedish Buildings. Journal of Environmental Protection, 5, 1022-1036. &lt;br /&gt;http://dx.doi.org/10.4236/jep.2014.511102</mixed-citation></ref><ref id="scirp.66551-ref57"><label>57</label><mixed-citation publication-type="other" xlink:type="simple">Swedish Work Environment Authority. Workplace Design, Provisions AFS 2009: 2. &lt;br /&gt;https://www.av.se/globalassets/filer/publikationer/foreskrifter/engelska/workplace-design-provisions-afs2009-2.pdf</mixed-citation></ref><ref id="scirp.66551-ref58"><label>58</label><mixed-citation publication-type="journal" xlink:type="simple"><name name-style="western"><surname>Hope-Simpson</surname><given-names> R.E. </given-names></name>,<etal>et al</etal>. (<year>1958</year>)<article-title>The Epidemiology of Non-Infectious Diseases</article-title><source> Journal of the Royal Society of Health</source><volume> 78</volume>,<fpage> 593</fpage>-<lpage>599</lpage>.<pub-id pub-id-type="doi"></pub-id></mixed-citation></ref><ref id="scirp.66551-ref59"><label>59</label><mixed-citation publication-type="other" xlink:type="simple">Gelperin, A. (1973) Humidification and Upper Respiratory Infection Incidence. Heating, Piping, Air Conditioning, 45, 3.</mixed-citation></ref><ref id="scirp.66551-ref60"><label>60</label><mixed-citation publication-type="journal" xlink:type="simple"><name name-style="western"><surname>Sale</surname><given-names> C.S. </given-names></name>,<etal>et al</etal>. (<year>1972</year>)<article-title>Humidification to Reduce Respiratory Illnesses in Nursery School Children</article-title><source> Southern Medical Journal</source><volume> 65</volume>,<fpage> 882</fpage>-<lpage>885</lpage>.<pub-id pub-id-type="doi"></pub-id></mixed-citation></ref><ref id="scirp.66551-ref61"><label>61</label><mixed-citation publication-type="other" xlink:type="simple">Ritzel, G. (1966) Sozialmedizinsche Erhebungen zur Pathogenese und prophylare von Erkaltungskankheiten. Zeitschrift für Pr?ventivmedizin, 11, 9-16. &lt;br /&gt;http://dx.doi.org/10.1007/BF02031776 </mixed-citation></ref><ref id="scirp.66551-ref62"><label>62</label><mixed-citation publication-type="other" xlink:type="simple">NCHS (National Center for Health Statistics) (1975) Acute Conditions, Incidence and Associated Disability, United States July 1973-June 1974. National Center for Health Statistics, DHEW Publ. No. (HRA) 76-1529, Rockville.</mixed-citation></ref><ref id="scirp.66551-ref63"><label>63</label><mixed-citation publication-type="journal" xlink:type="simple"><name name-style="western"><surname>Green</surname><given-names> G.H. </given-names></name>,<etal>et al</etal>. (<year>1979</year>)<article-title>The Effect of Indoor Relative Humidity on Colds</article-title><source> ASHRAE Transactions</source><volume> 85</volume>,<fpage> 747</fpage>-<lpage>757</lpage>.<pub-id pub-id-type="doi"></pub-id></mixed-citation></ref><ref id="scirp.66551-ref64"><label>64</label><mixed-citation publication-type="other" xlink:type="simple">Swedish Work Environment Authority. Sick-Buildings. &lt;br /&gt;https://www.av.se/inomhusmiljo/inomhusmiljo-och-halsobesvar/</mixed-citation></ref><ref id="scirp.66551-ref65"><label>65</label><mixed-citation publication-type="other" xlink:type="simple">Myc-Tech, A.B. Studie—Gr?nsv?rden f?r koldioxid i byggnader, in Swedish, 2012-06-27. &lt;br /&gt;info@myctech.com </mixed-citation></ref><ref id="scirp.66551-ref66"><label>66</label><mixed-citation publication-type="other" xlink:type="simple">National Research Council Canada. Indoor Air Quality Guidelines and Standards, RR-204, March 2005.</mixed-citation></ref><ref id="scirp.66551-ref67"><label>67</label><mixed-citation publication-type="other" xlink:type="simple">EU (91/322/EEG). &lt;br /&gt;http://eurlex.europa.eu/LexUriServ/LexUriServ.do?uri=DD:05:05:31991L0322</mixed-citation></ref><ref id="scirp.66551-ref68"><label>68</label><mixed-citation publication-type="other" xlink:type="simple">The National Institute for Occupational Safety and Health (NIOSH). &lt;br /&gt;http://www.cdc.gov/niosh/idlh/124389.html</mixed-citation></ref></ref-list></back></article>