<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article  PUBLIC "-//NLM//DTD Journal Publishing DTD v3.0 20080202//EN" "http://dtd.nlm.nih.gov/publishing/3.0/journalpublishing3.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="3.0" xml:lang="en" article-type="research article"><front><journal-meta><journal-id journal-id-type="publisher-id">OJU</journal-id><journal-title-group><journal-title>Open Journal of Urology</journal-title></journal-title-group><issn pub-type="epub">2160-5440</issn><publisher><publisher-name>Scientific Research Publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.4236/oju.2015.512035</article-id><article-id pub-id-type="publisher-id">OJU-62021</article-id><article-categories><subj-group subj-group-type="heading"><subject>Articles</subject></subj-group><subj-group subj-group-type="Discipline-v2"><subject>Medicine&amp;Healthcare</subject></subj-group></article-categories><title-group><article-title>
 
 
  Testicular Seminoma and Peritonitis about One Case at the Yalgado Ouedraogo University Hospital of Ouagadougou
 
</article-title></title-group><contrib-group><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>ayi</surname><given-names>Zongo</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="corresp" rid="cor1"><sup>*</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Moussa</surname><given-names>Bazongo</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Mamadou</surname><given-names>Windsouri</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Mousa</surname><given-names>Kaboré</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Edgar</surname><given-names>Ouangré</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Maurice</surname><given-names>Zida</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Aimé</surname><given-names>Sosthène Ouédraogo</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Aboubacar</surname><given-names>Hirrhum Bambara</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Augustin</surname><given-names>Tozoula Bambara</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Si</surname><given-names>Simon Traore</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Ahmadou</surname><given-names>Dem</given-names></name><xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib></contrib-group><aff id="aff2"><addr-line>Division of Pathologic Anatomy, Yalgado Ouédraogo University Hospital, Ouagadougou, Burkina Faso</addr-line></aff><aff id="aff3"><addr-line>Oncology Institue Joliot Curie, Dakar, Senegal</addr-line></aff><aff id="aff1"><addr-line>Division of General Surgery, Yalgado Ouédraogo University Hospital, Ouagadougou, Burkina Faso</addr-line></aff><author-notes><corresp id="cor1">* E-mail:<email>colsa3@yahoo.fr(AZ)</email>;</corresp></author-notes><pub-date pub-type="epub"><day>17</day><month>12</month><year>2015</year></pub-date><volume>05</volume><issue>12</issue><fpage>220</fpage><lpage>223</lpage><history><date date-type="received"><day>2</day>	<month>November</month>	<year>2015</year></date><date date-type="rev-recd"><day>accepted</day>	<month>15</month>	<year>December</year>	</date><date date-type="accepted"><day>18</day>	<month>December</month>	<year>2015</year></date></history><permissions><copyright-statement>&#169; Copyright  2014 by authors and Scientific Research Publishing Inc. </copyright-statement><copyright-year>2014</copyright-year><license><license-p>This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/</license-p></license></permissions><abstract><p>
 
 
  Introduction: Testicular seminoma is a highly lymphophilic germ cell tumor. It is the most common germ cell tumor in young adults. We are reporting one case of testicular seminoma complicated with an acute generalized peritonitis (AGP), in order to describe the circumstances of diagnosis and discuss about treatment. Observation: It involved a 39-year-old patient, admitted for vague abdominal pains that were evolving since 72 hours with a history of right orchiectomy because of testicular seminoma in 2011. The analysis revealed a peritoneal syndrome, a right inguinal lymphadenopathy of 10 cm diameter and an empty right scrotum. The exploration revealed fistulized necrotic retro-peritoneal lymphadenopathies in the peritoneal cavity and ileal perforation on contact with these lymphadenopathies. Necrosectomy and ileal resections were performed. After the operation, the scanner revealed a conglomeration of retro-peritoneal adenomegalies extending to the right femoral region associated with bilateral pleurisy. The β-HCG and the LDH were 8000 IU/L and 24,500 IU/L, respectively. The seminoma was ranked T3N3M1. The immediate post-operative care was uneventful. The patient was lost from sight for a month and was readmitted in a context of alteration of his general condition. He died before the end of the pre-chemotherapeutic assessment. Conclusion: Scrotal mass is the usual way of revelation of testicular seminoma. In poorly followed-up cases, exceptional complications such as peritonitis may occur and are direct consequences of poor prognosis.
 
</p></abstract><kwd-group><kwd>Seminoma</kwd><kwd> Testicle</kwd><kwd> Peritonitis</kwd><kwd> Treatment</kwd><kwd> Prognosis</kwd></kwd-group></article-meta></front><body><sec id="s1"><title>1. Introduction</title></sec><sec id="s2"><title>2. Observation</title><p>It involved a 39-year-old patient admitted to the visceral emergency unit on 14<sup>th</sup> March 2013 for vague abdominal pains evolving since 72 hours. We noted a history of right orchiectomy, because of testicular seminoma performed in 2011. The analysis revealed a peritoneal syndrome, a right orchiectomy scar, a right inguinal lymphadenopathy of 10 cm diameter and an empty right scrotum. During the emergency laparotomy recommended for acute generalized peritonitis, the exploration revealed fistulized necrotic retro-peritoneal lymphadenopathies in the peritoneal cavity. Was also noted an invasion of the ileal segment on contact with ganglion necrosis. The peritonitis was due to the perforation of this loop. An immediate ileoileal termino terminal anastomosis was performed after Ganglion necrosectomy and ileal resection.</p><p>A posteriori, the diagnosis of acute generalized peritonitis by ileal perforation resulting from a tumor invasion of a seminoma was retained. The immediate postoperative care was uneventful. The assessment was completed after the emergency. The abdominal and pelvic scan made one week before the operation highlighted inguinal and retroperitoneal lymphadenopathies (<xref ref-type="fig" rid="fig1">Figure 1</xref>, <xref ref-type="fig" rid="fig2">Figure 2</xref>) associated a bilateral pleurisy (<xref ref-type="fig" rid="fig3">Figure 3</xref>) beta chorionic gonadotropin hormones (β-HCG) and lactate dehydrogenase (LDH) were 8000 IU/L and 24,500 IU/L, respectively. The seminoma was ranked T3N3M1. The patient was lost from sight for a month and was readmitted in a context of alteration of his general condition. He died before the end of the pre-chemotherapeutic assessment.</p><fig id="fig1"  position="float"><label><xref ref-type="fig" rid="fig1">Figure 1</xref></label><caption><title> Right inguinal adenopathy with areas of necrosis</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/2-5000308x7.png"/></fig><fig id="fig2"  position="float"><label><xref ref-type="fig" rid="fig2">Figure 2</xref></label><caption><title> Necrotic lymph nodes below diaphragmatic and right hydronephrosis</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/2-5000308x8.png"/></fig><fig id="fig3"  position="float"><label><xref ref-type="fig" rid="fig3">Figure 3</xref></label><caption><title> Minimal bilateral pleurisy</title></caption><graphic mimetype="image"   position="float"  xlink:type="simple"  xlink:href="http://html.scirp.org/file/2-5000308x9.png"/></fig></sec><sec id="s3"><title>3. Discussion</title><p>Testicular seminoma is the most common malignant germ cell tumour in young adults [<xref ref-type="bibr" rid="scirp.62021-ref1">1</xref>] . Its ganglion extension is made successively towards the inguinal, iliac and retroperitoneal ganglion chains to reach the supra- diaphragmatic and cervical lymph nodes [<xref ref-type="bibr" rid="scirp.62021-ref3">3</xref>] . Testicular mass is the usual circumstance of discovery. Concerning the extra-digestive signs, a ganglion metastasis can be the way of discovery. This was the case in the study by Tazi et al. [<xref ref-type="bibr" rid="scirp.62021-ref6">6</xref>] where a left supra-clavicular lymphadenopathy (TROISIER) enabled diagnose a testicular tumor. Nguyen et al. [<xref ref-type="bibr" rid="scirp.62021-ref7">7</xref>] noted cerebral and splenic metastases as circumstances of diagnosis. The discovery of a testicular seminoma in the etiologic search for digestive manifestations was described. Thus, in the study of Felix et al. [<xref ref-type="bibr" rid="scirp.62021-ref4">4</xref>] , a retroperitoneal bilobed cystic mass which was responsible for the appendicular syndrome in 19-year- old young man enabled discover primary testicular tumor. In the same connection, Wehrsch&#252;ltz et al. [<xref ref-type="bibr" rid="scirp.62021-ref8">8</xref>] had diagnosed testicular tumour in the assessment of a cholestatic ictera by tumor invasion of the pancreas. Further cases of acute intestinal obstruction by tumor invasion of the small bowel were described [<xref ref-type="bibr" rid="scirp.62021-ref9">9</xref>] . Ali et al. reported a case of peritonitis resulting from a necrosis of the intra-abdominal seminoma in an undescended testicle [<xref ref-type="bibr" rid="scirp.62021-ref5">5</xref>] . However, an acute generalized peritonitis by ileal perforation resulting from a invasive seminoma like in our case is rarely reported in the literature. This situation must have been favoured by a natural evolution of a seminoma which was treated neither by chemotherapy nor by radiotherapy. Only a diagnostic orchiectomy was performed. These manifestations show in general an advanced phase of primary tumor, so a complicated form and thus occasion therapeutic difficulties. In our study, the lack of post-orchiectomy adjuvant treatment was a determining factor in the occurrence of acute generalized peritonitis. According to the literature, the ideal treatment of complicated forms is based on chemotherapy associating Bleomycin, Etoposide and Cisplatin (BEP protocol) for 3 to 4 cycles [<xref ref-type="bibr" rid="scirp.62021-ref10">10</xref>] . Surgery can be recommended for the removal of any post-chemotherapy persistent residual mass [<xref ref-type="bibr" rid="scirp.62021-ref10">10</xref>] . In our study, before the emergency of abdominal surgery, we first of all treated peritonitis and perforation. Later, we proposed chemotherapy which could not be afforded by the patient. However the introduction of social security in favour of the entire population could enable better access of patients to quality care. Testicular seminoma is reputed to be a cancer of good prognosis even when metastatic. As evidence in the study by Wehrsch&#252;ltz et al. [<xref ref-type="bibr" rid="scirp.62021-ref8">8</xref>] and Nguyen et al. [<xref ref-type="bibr" rid="scirp.62021-ref7">7</xref>] , the good evolution with a complete decrease of the symptoms with no recurrence after two years in their patients who were at a metastatic phase (pancreas, spleen, brain) of their testicular germ cell tumors. In our case, the prognosis of the patient was somber because not only of the advanced stage of the disease but also the desperate evolution of an acute generalized peritonitis occurring in a patient who was already weakened. Furthermore, the lack of specific treatment with chemotherapy was a factor of mortality. Improved prognosis goes through an early diagnosis of testicular seminoma, an adjuvant treatment after orchiectomy and a careful oversight.</p></sec><sec id="s4"><title>4. Conclusion</title><p>Scrotal mass is the common way of revelation of testicular seminoma. Acute generalized peritonitis by ileal perforation by invasive seminoma remains an exceptional and serious complication. It requires surgical treatment on a weakened patient. The prognosis of this association is bad.</p></sec><sec id="s5"><title>Cite this paper</title><p>NayiZongo,MoussaBazongo,MamadouWindsouri,MousaKabor&#233;,EdgarOuangr&#233;,MauriceZida,Aim&#233; Sosth&#232;neOu&#233;draogo,Aboubacar HirrhumBambara,Augustin TozoulaBambara,Si SimonTraore,AhmadouDem, (2015) Testicular Seminoma and Peritonitis about One Case at the Yalgado Ouedraogo University Hospital of Ouagadougou. 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