Ashwagandha is botanically called Withania somnifera Dunal and is a member of the Solanaceaae family. It is commonly called Indian Ginseng or Winter Cherry. The name “Ashagwandha” literally means “smell of horse” since the herb’s fresh roots smell like horse and the fact that one who takes the herb extracts may develop the vitality and strength of a horse [2] . It has multifarious rejuvenative effects on the human body and thus referred to as a “royal herb”. The herb is multi-purpose in nature and acts on different body systems such as the immune system, neurological system, the endocrinal system, the energy-production system, and the reproductive system.

Extensive studies have been done on adaptogen due to its popularity. It has been studied as an antioxidant, adaptogen, anxiplytic, anticancer, antidepressant, thyroid modulating, cardio-protective, immunomodulating, antifungal, antibacterial, neuro-protective, anti-inflammatory, hematopoietic and cognitive enhancing agent. Ashwagandha is made up of a variety of constituents like sitoindoside, withanolides, among other alkaloids that are medicinally and pharmacologically vital since they protect cells from oxidative damage and disease. A series of tests conducted to establish the anti-stress qualities of sitoindoside VII and sitoindoside VIII deduced that both portrayed anti-stress activity. Rats were also used to test sitoindoside IX and X for immunomodulatory and central nervous system effects that impact on memory, stress, and learning [1] . Stress-induced gastric ulcer was also slightly reduced by the sitoindoside IX and X.

Bacopa monnieri has been used over time in Ayurvedic medicine, be it alone or together with other herbs, to boost memory and learning, as a sedative, and an anti-epileptic [3] . Its English name is water hyssop and is a famous aquarium plant that is normally grown in wet tropical environments. Pharmacologists and phytotherapists have grown a lot of interest in this plant and a survey conducted in Australia showed it to be the most popular memory enhancer among Australian consumers of ages 60 - 64 [4] .

B. monnieri entire plant or alcohol extracts has been tested on animals and has showed results of enhanced motor learning and grasping, memory consolidation, and retention in rats. Saponins (bacopasides, bacosides, or bacopasapoinins) have been credited with the memory-enhancing abilities of B. monnieri. Bacopa saponins constituents have been proven to enhance mental retention that triggers avoidance response in rats, as well as reversing amnesic effects of scopolamine, neurotoxin, electroshock, phenytoin, and immobilization stress [5] . Hypothesized action mechanisms include y-aminobutyric acid-ergic modulation, cholinergic upregulation, brain protein synthesis, antioxidant effects, 5-HT agonism, and brain stress hormones modulation. Extracts from Bacopa have also ameliorated neurotoxin effects of aluminum and nicotine. It has also lowered the levels of Beta-amyloid in the brain of a doubly transgenicmodel of quick amyloid deposition (PSAPP mice), pointing to action mechanisms relevant to Alzheimer’s disease [6] .