<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article  PUBLIC "-//NLM//DTD Journal Publishing DTD v3.0 20080202//EN" "http://dtd.nlm.nih.gov/publishing/3.0/journalpublishing3.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="3.0" xml:lang="en" article-type="research article"><front><journal-meta><journal-id journal-id-type="publisher-id">OJS</journal-id><journal-title-group><journal-title>Open Journal of Statistics</journal-title></journal-title-group><issn pub-type="epub">2161-718X</issn><publisher><publisher-name>Scientific Research Publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.4236/ojs.2013.32009</article-id><article-id pub-id-type="publisher-id">OJS-29912</article-id><article-categories><subj-group subj-group-type="heading"><subject>Articles</subject></subj-group><subj-group subj-group-type="Discipline-v2"><subject>Physics&amp;Mathematics</subject></subj-group></article-categories><title-group><article-title>
 
 
  Composite Quantile Regression for Nonparametric Model with Random Censored Data
 
</article-title></title-group><contrib-group><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>ong</surname><given-names>Jiang</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="corresp" rid="cor1"><sup>*</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Weimin</surname><given-names>Qian</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="corresp" rid="cor1"><sup>*</sup></xref></contrib></contrib-group><aff id="aff1"><addr-line>Department of Mathematics, Tongji University, Shanghai, China</addr-line></aff><author-notes><corresp id="cor1">* E-mail:<email>jrtrying@126.com(OJ)</email>;<email>wmqian2003@yahoo.com.cn(WQ)</email>;</corresp></author-notes><pub-date pub-type="epub"><day>16</day><month>04</month><year>2013</year></pub-date><volume>03</volume><issue>02</issue><fpage>65</fpage><lpage>73</lpage><history><date date-type="received"><day>May</day>	<month>29,</month>	<year>2012</year></date><date date-type="rev-recd"><day>June</day>	<month>30,</month>	<year>2012</year>	</date><date date-type="accepted"><day>July</day>	<month>15,</month>	<year>2012</year></date></history><permissions><copyright-statement>&#169; Copyright  2014 by authors and Scientific Research Publishing Inc. </copyright-statement><copyright-year>2014</copyright-year><license><license-p>This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/</license-p></license></permissions><abstract><p>
 
 
   The composite quantile regression should provide estimation efficiency gain over a single quantile regression. In this paper, we extend composite quantile regression to nonparametric model with random censored data. The asymptotic normality of the proposed estimator is established. The proposed methods are applied to the lung cancer data. Extensive simulations are reported, showing that the proposed method works well in practical settings.
     
 
</p></abstract><kwd-group><kwd>Kaplan-Meier Estimator; Censored Data; Composite Quantile Regression; Kernel Estimator; Nonparametric Model</kwd></kwd-group></article-meta></front><body><sec id="s1"><title>1. Introduction</title><p>Consider the following nonparametric regression model with random censored data:</p><disp-formula id="scirp.29912-formula50478"><label>(1)</label><graphic position="anchor" xlink:href="2-1240111\32f97413-0bb7-43cf-9183-7d86c04e7fb7.jpg"  xlink:type="simple"/></disp-formula><p>where <img src="2-1240111\72d805c9-3a54-4a3b-a0e2-6cfeb0ebf43c.jpg" /> is an unknown smoothing function, <img src="2-1240111\8039bc1d-9124-46c0-a37b-93ffcf0bc667.jpg" />is a positive function representing the standard deviation and <img src="2-1240111\2df70c16-3c60-4811-beed-0cbd000494f5.jpg" /> is the random error with mean 0 and variance 1. Let C denote the censoring variable, whose distribution may depend on U, where U is vector of observed covariates. In this paper, we focus on random right censoring, we only observe the triples<img src="2-1240111\3b8dce03-ba8c-4fb2-881c-d9c18cbdc5af.jpg" />, where <img src="2-1240111\330c0955-60c1-4c2c-9490-c85bb2cc05ea.jpg" /> and <img src="2-1240111\ca6c11b5-21c3-41ec-8ed5-a74a96de4746.jpg" /> are the observed response variable and the censoring indicator respectively, where <img src="2-1240111\ce0d2917-bacb-4f2d-982b-a69a9556617b.jpg" /> is the survival time.</p><p>Censored quantile regression was first studied by [<xref ref-type="bibr" rid="scirp.29912-ref1">1</xref>] for fixed censoring. [<xref ref-type="bibr" rid="scirp.29912-ref2">2</xref>] proposed an estimator for a conditional quantile assuming that the regression models at lower quantiles are all linear. A recursively weighted estimation procedure that can be regarded as a generalization of the Kaplan-Meier estimator to conditional quantiles was described in their paper. Afterward, [<xref ref-type="bibr" rid="scirp.29912-ref3">3</xref>] presented an alternative approach that is based on the Nelson-Aalen estimator of the cumulative hazard function but still requires the same global-linearity assumption as Portnoy’s. Their method provides a more direct approach to the asymptotic theory and a simpler computation algorithm. More recent studies by [<xref ref-type="bibr" rid="scirp.29912-ref4">4</xref>], proposed to overcome the global-linearity assumption by directly estimating the conditional censoring distribution nonparametrically using the local Kaplan-Meier method. Their computational algorithm is more stable and simpler to implement than Portnoy’s or Peng and Huang’s. Moreover, the local nonparametric estimator on which the model is based performs best when the covariates can be assumed independent.</p><p>Intuitively, the composite quantile regression (CQR) should provide estimation efficiency gain over a single quantile regression; see [<xref ref-type="bibr" rid="scirp.29912-ref5">5</xref>]. A composite quantile regression model assumes that there exist common covariate effects in a range of quantiles such that the quantile levels only differ in terms of the intercept. From a more general regression perspective, composite quantile regression seeks to model a set of parallel regression curves, and thus it can be viewed as a compromise between a set of quantile regression curves with different intercepts and slopes and a single summary regression curve. [<xref ref-type="bibr" rid="scirp.29912-ref6">6</xref>] proposed the local polynomial CQR estimators (LCQR) for estimating the nonparametric regression function and its derivative. It is shown that the local CQR method can significantly improve the estimation efficiency of the local least squares estimator for commonlyused non-normal error distributions. Furthermore, [<xref ref-type="bibr" rid="scirp.29912-ref7">7</xref>] studied semiparametric CQR estimates for semiparametric varying-coefficient partially linear model. They compared CQR with least squares and quantile regression, and the results showed that CQR outperformed both least squares and quantile regression. [<xref ref-type="bibr" rid="scirp.29912-ref8">8</xref>] considered CQR estimates for single-index models. Recently, [<xref ref-type="bibr" rid="scirp.29912-ref9">9</xref>] extended the CQR method to linear model with randomly censored data. This motivates us to extend the CQR method to nonparametric model with censored data (LCQRC).</p><p>The paper is organized as follows. In Section 2, local composite quantile regression for nonparametric model with censored data is introduced, and the main theoretical results are also given in this section. Both simulation examples and a real data application are given in Section 3 to illustrate the proposed procedures. Final remarks are given in Section 4. The technical proofs are deferred to the Appendix.</p></sec><sec id="s2"><title>2. Methodology</title><sec id="s2_1"><title>2.1. Local Composite Quantile Regression with Censored Data</title><p>We first consider an ideal situation where<img src="2-1240111\8d340117-d985-4bfb-973c-881b73907ca2.jpg" />, the conditional cumulative distribution function of the survival time <img src="2-1240111\d312268b-1185-41ed-9c60-9435d800f80d.jpg" /> given<img src="2-1240111\96e91bec-b9c3-44a3-a8a2-31f1fb0dd340.jpg" />, is assumed to be known. In this case, we define the following weight function:</p><disp-formula id="scirp.29912-formula50479"><label>(2)</label><graphic position="anchor" xlink:href="2-1240111\4331a728-3e8b-4ce3-b7ed-7595520d75ff.jpg"  xlink:type="simple"/></disp-formula><p><img src="2-1240111\7a26bc98-7cc9-4b38-b943-506ea58d3f47.jpg" />. In reality, <img src="2-1240111\db0b16c7-e2c4-41d0-a299-0f8f9c4dac01.jpg" />is unknown and has to be estimated. We propose to estimate <img src="2-1240111\eaca9fd9-c1bd-418f-a253-6ee1bfa3848b.jpg" /> nonparametrically using the local Kaplan-Meier estimator</p><p><img src="2-1240111\1e940169-161a-47c9-a6f1-f03342825e03.jpg" /></p><p>where <img src="2-1240111\dc170441-e975-4de5-b4a7-624c4f54d90b.jpg" /> and</p><p><img src="2-1240111\08483570-4930-45b4-a7fd-a0d08a001a8c.jpg" />, where</p><p><img src="2-1240111\863a9d47-dad2-4f3e-86f7-0df06713a8ed.jpg" />is a smooth kernel function, <img src="2-1240111\3538dd08-c548-4c07-99a3-04b4e7e1e6aa.jpg" />is the bandwidth converging to zero as<img src="2-1240111\8c57e366-bdd5-4c06-ae33-f097c059db0d.jpg" />. By plugging <img src="2-1240111\6eb4ceac-dad1-42fa-8a1e-277f953d9b73.jpg" /> into (2), we obtain the estimated local weights</p><p><img src="2-1240111\f8a373f7-ead1-4f74-b220-28ec2827b91e.jpg" />. Consider estimating the value of <img src="2-1240111\e62b0f72-fb8e-48a2-bb1b-4edaf3678f46.jpg" /> at</p><p><img src="2-1240111\d1b55af8-b0c3-4b98-bac5-89f184d6e123.jpg" />. The LCQRC procedure estimates<img src="2-1240111\22c281c6-d7fb-4d56-8277-dffac15146ff.jpg" />, defined by<img src="2-1240111\f41a6822-5a9d-4a6c-ba25-7e834d2a0920.jpg" />, via minimizing the locally weighted objective function</p><p><img src="2-1240111\d67904a8-8075-4bad-a862-014951f603b7.jpg" /></p><p>where<img src="2-1240111\09d9b84c-cf2d-4b7f-b6c2-19458736e4c6.jpg" />, be q check loss functions at q quantile positions: <img src="2-1240111\6a170c2c-8349-4a11-921e-2a06e57d98be.jpg" />and <img src="2-1240111\f61e11b2-3223-4cf2-9e1b-aa38e279ad17.jpg" /> is any value sufficiently large to exceed all<img src="2-1240111\b81f675d-8898-4069-a6fc-72a320634784.jpg" />.</p><p>Remark 1. The detail explant of <img src="2-1240111\dda83a18-a87c-4b6e-8591-78a9b6af6193.jpg" /> can see Remark 1 of [<xref ref-type="bibr" rid="scirp.29912-ref4">4</xref>].</p></sec><sec id="s2_2"><title>2.2. Asymptotic Properties</title><p>Denote by <img src="2-1240111\87726f6a-6eaa-4561-aeed-f5c4ce6120a8.jpg" /> the marginal density function of the covariate<img src="2-1240111\de2ac7e8-8edc-4e84-a6f5-0096c079c622.jpg" />, <img src="2-1240111\fb26d023-c48e-434d-bb8c-c32898ac155f.jpg" />and</p><p><img src="2-1240111\45843c59-d234-46f3-a73e-6272b864804c.jpg" />. To prove main results in this paperthe following technical conditions are imposed.</p><p>A1. The functions <img src="2-1240111\93b6307e-ddac-460c-b7f3-f2d0c4084625.jpg" /> and <img src="2-1240111\bd81be89-337f-4c6d-99c4-45a27ebc0073.jpg" /> have first derivatives with respect to<img src="2-1240111\4e753a8e-f9c7-4870-9460-45cb650cb78e.jpg" />, denoted as <img src="2-1240111\139667d7-b3d8-4441-9c07-ab56a2bc97e0.jpg" /> and<img src="2-1240111\c1699355-4793-452e-816b-c837f7475a4c.jpg" />, which are uniformly bounded away from infinity. In addition, <img src="2-1240111\552b7bfd-2e20-4feb-90ea-28eb4213b52a.jpg" />and <img src="2-1240111\b97710f7-d337-4b5a-b715-f9f011182f87.jpg" /> have bounded second order partial derivatives with respect to U.</p><p>A2. <img src="2-1240111\bd287f2b-ef58-4f8c-893c-3a43bd2e0b01.jpg" />is positive definite matrix.</p><p>A3. <img src="2-1240111\dd7fb8c9-c7fc-4b19-a92c-fff7902b7e62.jpg" />has a continuous second derivative in the neighborhood of<img src="2-1240111\8cfabd9c-1c72-4b01-8ee1-1fec095ceaaf.jpg" />.</p><p>A4. <img src="2-1240111\80fec03c-df21-4ce4-a903-f7080920f2b0.jpg" />is differentiable and positive in the neighborhood of<img src="2-1240111\492f1973-52e5-4b3b-a5f4-ca572da3f59d.jpg" />.</p><p>A5. The conditional variance <img src="2-1240111\ec3c6e49-bb7d-4387-a872-6167f0da0d55.jpg" /> is continuous in the neighborhood of<img src="2-1240111\baf01425-8e4d-4868-9471-90420f37d368.jpg" />.</p><p>A6. Assume that the error has a symmetric distribution with a positive density<img src="2-1240111\29ec3e85-66b7-4e2e-ac7e-59257c484c8f.jpg" />.</p><p>Remark 2. Assumption A1 is needed for the local Kaplan-Meier estimator. It allows us to obtain the local expansions of <img src="2-1240111\e2c37688-bb03-4064-bcf3-8133863e2f96.jpg" /> and <img src="2-1240111\4230e2a2-1516-4ad8-896e-eff8193cfbf4.jpg" /> in the neighborhood of<img src="2-1240111\aa03df37-e9d9-40b4-a86b-c85074f30f35.jpg" />, and to obtain the uniform consistency and the linear representation of<img src="2-1240111\0548cfbf-2787-43df-b514-070ad5bd2d1f.jpg" />, which are needed for deriving the asymptotic normality result. Assumption A2 ensures that the expectation of the estimating function has a unique zero, and it is needed to establish the asymptotic distribution. Assumptions A3- A6 are the same conditions for establishing the asymptotic normality of local composite quantile regression ([<xref ref-type="bibr" rid="scirp.29912-ref6">6</xref>]).</p><p>We state the asymptotic normality for <img src="2-1240111\a54154bd-4e24-4a8a-9fa0-5d9ae38026a7.jpg" /> in the following theorem.</p><p>Theorem 1. Assume that the triples <img src="2-1240111\fd89913f-69b5-42d5-926d-3f3681c49b03.jpg" /> constitute and i.i.d. multivariate random sample, and that the censoring variable <img src="2-1240111\a76a3138-0d66-4633-9b8a-2ad1aedaa863.jpg" /> is independent of <img src="2-1240111\1a26edac-8e19-43ac-90d4-7b051a114b84.jpg" /> conditional on the covariate<img src="2-1240111\79335959-5c0f-4334-9090-fd9cf36d9cf6.jpg" />. Suppose that <img src="2-1240111\87b061d7-7065-4f26-9a60-5d2fce8e8987.jpg" /> is an interior of the support of<img src="2-1240111\2e5bc047-882f-4f3c-805c-7f9cd30b4a10.jpg" />. Under the regularity conditions A1-A6, if <img src="2-1240111\736154a0-4ce3-4c60-8bc5-56fe3f44475e.jpg" /> and<img src="2-1240111\8db00633-ca12-4be1-97a9-6a1883512580.jpg" />, then</p><p><img src="2-1240111\dc15ab56-80f7-435e-9830-c2ad7a3cc412.jpg" /></p><p>where <img src="2-1240111\1dbf97b6-0263-4279-a741-52c9778d4f4c.jpg" /> stands for convergence in distribution and</p><p><img src="2-1240111\238768e6-ef55-4a4d-8eae-3cb7a99152c3.jpg" />, where</p><p><img src="2-1240111\e53ffa64-9a1d-4fe5-b4b7-e15be9a12817.jpg" /></p><p><img src="2-1240111\fc4ed5c7-46e8-4184-b87c-19e071e8d542.jpg" /></p><p>and<img src="2-1240111\1a0758b3-5d59-4eb8-bd9f-4e58d9fdb527.jpg" />.</p></sec></sec><sec id="s3"><title>3. Numerical Studies</title><p>In this section, we conduct simulation studies to assess the finite sample performance of the proposed procedures and illustrate the proposed methodology on a lung cancer data set. Moreover, we compare the performance of the newly proposed method with LCQR ([<xref ref-type="bibr" rid="scirp.29912-ref6">6</xref>]) and nonparametric quantile regression with censored data (NQRC) that was proposed by [<xref ref-type="bibr" rid="scirp.29912-ref10">10</xref>].</p><p>In the proposed compute process, we take</p><p><img src="2-1240111\6c3479a1-2bbf-4020-be95-429c7120c22a.jpg" />and</p><p><img src="2-1240111\5d1e89c9-53f4-4f6e-8977-48396107e9b4.jpg" />. The bandwidth h<sup>*</sup> can be obtained by 10-fold cross-validation method (see [<xref ref-type="bibr" rid="scirp.29912-ref4">4</xref>]), and we use the short-cut strategy method to select <img src="2-1240111\e5eeb487-ec85-4969-9bed-66cd8a2e22fb.jpg" /> (see [<xref ref-type="bibr" rid="scirp.29912-ref6">6</xref>]).</p><sec id="s3_1"><title>3.1. Example 1</title><p>The data are generated from the following model</p><p><img src="2-1240111\41c1d713-515c-400c-878e-d8df8cb0a903.jpg" /></p><p>where <img src="2-1240111\fe0ca8c5-dfec-4a08-b145-f260ba5d54c7.jpg" /> is uniformly distributed on <img src="2-1240111\cc715397-b50f-44f1-9850-cadc4a987274.jpg" /> and <img src="2-1240111\998ef1eb-1d38-4403-9e24-11d00926942a.jpg" /> is i.i.d. standard normal random variables. The censoring variable <img src="2-1240111\ca2d3cce-3258-4e87-b703-1ba60233e0d7.jpg" /> and<img src="2-1240111\f9d0138b-7f03-4f83-81d5-81b08a448e0c.jpg" />. The value of the constant c in the model determines the censoring proportion. In our simulations, we consider three censoring rates (CR): 20%, 30% and 40%. For each censoring rate, the sample sizes are taken to be 100 and 200. To evaluate the finite sample performance of our estimator. Two distance measures are approximated, the first one the mean absolute deviation error (MADE) is given by<img src="2-1240111\4d75dc4b-33f2-4b4e-b872-d7817ecdc2db.jpg" />, and the second one the mean squared error (MSE) defines as</p><p><img src="2-1240111\a3cd7412-3e30-4972-b375-05b5c4c129a3.jpg" />. Furthermore, we define the rate of MADE and MSE which are</p><p><img src="2-1240111\42a13d02-ac73-49d4-8562-777e6c08d882.jpg" />and</p><p><img src="2-1240111\42e7aff1-59ec-4b78-a199-2b9f4aafcbf2.jpg" />.</p><p>For right censored data, quantile functions with <img src="2-1240111\a816416b-f51c-4784-8ebc-28961b2eea07.jpg" /> close to 1 may not be identifiable due to censorship. In our similations, we consider <img src="2-1240111\32cd1d54-6a3a-4cac-8bf5-ca4bcdfbce8e.jpg" /> for LCQR and LCQRC estimators. The means and standard deviations of MADE, MSE, RMADE and RMSE are respectively reported in <xref ref-type="table" rid="table1">Table 1</xref> and <xref ref-type="table" rid="table2">Table 2</xref>. From Tables 1 and 2, we can make the following observations: the performance of proposal method is better than that of LCRQ and NQRC. Moreover, LCQRC estimators are much more accurate when sample sizes increase. <xref ref-type="fig" rid="fig1">Figure 1</xref> summarize the Curve estimates for three censoring rates of 20%, 30% and 40% with different sample sizes. It shows that the performance of LCQRC is very close to the true value.</p></sec><sec id="s3_2"><title>3.2. Example 2</title><p>It is necessary to investigate the effect of heteroscedastic errors. The observations<img src="2-1240111\8ccdef9c-3ecd-44e7-b811-7cef6c659ae7.jpg" />, are generated from following model</p><p><img src="2-1240111\b32de0c1-9285-4a65-a0be-9758892c54b9.jpg" /></p><p>where <img src="2-1240111\b69df8e5-d95b-46f2-8d57-0b18f3437a44.jpg" /> and <img src="2-1240111\e6eefe20-253e-4c47-a671-b60f95fa7ab1.jpg" /> are generated following the same way as in Example 1. The means and standard deviations of MADE, MSE, RMADE and RMSE are respectively reported in <xref ref-type="table" rid="table3">Table 3</xref> and <xref ref-type="table" rid="table4">Table 4</xref>. The</p><p><xref ref-type="table" rid="table1">Table 1</xref>. Simulation results of <img src="2-1240111\1a54061c-2054-4714-a7d1-f218c82f2d51.jpg" /> with n = 100 for Example 1.</p><p><img src="2-1240111\2419ea3f-2c08-4556-8f0b-4e4432ed9d9a.jpg" /></p><p><xref ref-type="table" rid="table2">Table 2</xref>. Simulation results of <img src="2-1240111\1e06b80d-33fa-43fa-a583-59fb1b323d29.jpg" /> with n = 200 for Example 1.</p><p><img src="2-1240111\f7de5bf3-2b81-4a5a-b6e2-1d2efcd940c9.jpg" /></p><p><xref ref-type="table" rid="table3">Table 3</xref>. Simulation results of <img src="2-1240111\28a3a0af-342c-4bff-a8be-8acd6ba8d4a9.jpg" /> with n = 100 for Example 2.</p><p><img src="2-1240111\f1258905-c7f9-4c37-b376-be716481a294.jpg" /></p><p><xref ref-type="table" rid="table4">Table 4</xref>. Simulation results of <img src="2-1240111\daf106bb-8928-4caa-bd26-75f2fd41b3ae.jpg" /> with n = 200 for Example 2.</p><p><img src="2-1240111\4f00d2c8-44ff-4923-9c80-0a7c0e845095.jpg" /></p><p>performance of LCQRC is presented in <xref ref-type="fig" rid="fig2">Figure 2</xref>. The results of Example 1 and Example 2 show very similar messages.</p></sec><sec id="s3_3"><title>3.3. Example 3</title><p>As an illustration, we now apply the proposed LCQRC to the lung cancer data. The data contain 228 observations on ten variables. The censoring percentage is 27%, so the estimators are expected to perform well. More details about the study can be found in [<xref ref-type="bibr" rid="scirp.29912-ref11">11</xref>], and the dataset is included in the R package<img src="2-1240111\67924fea-666c-445e-b1fd-bbcfbc75d43c.jpg" />. We are interested in estimating the conditional of survival time (in days) given age (in years). Here, we use model (1) to fit the lung cancer data, where <img src="2-1240111\635e575c-4cc9-4879-b05a-a504b8a5d8cf.jpg" /> is the <img src="2-1240111\a0f9760d-a1d0-4e4b-bb02-bac32ea87917.jpg" />(survival time) and U is the age/100. To evaluate the performance of our estimator. Two distance measures were approximatedthe first one the mean absolute deviation error</p><p><img src="2-1240111\541774f8-c459-4a8d-a4aa-596fd4f5b48b.jpg" />given by<img src="2-1240111\321ee1d7-a2c0-4214-9f8d-809c136d1aa4.jpg" />, and the second one the mean squared error <img src="2-1240111\742ae462-7513-474c-a4d1-bb6537459a6c.jpg" /> defined as</p><p><img src="2-1240111\c21a18a0-9813-411b-8836-c82fad547129.jpg" />, where<img src="2-1240111\28a8684f-0aa8-4cfb-a88b-e284a57e3170.jpg" />. Furthermore, we define the rate of <img src="2-1240111\19043d41-c292-4751-abfa-7ad9d5917d8d.jpg" /> and <img src="2-1240111\83089f1f-48a5-4578-84d0-9b19b4388894.jpg" /> which are</p><p><img src="2-1240111\51b8eb40-b3b5-4cf9-94a3-0d6a35cc47ee.jpg" />and</p><p><img src="2-1240111\01057d6e-db33-48a5-84f1-6030934a0553.jpg" />. Next, we report and compare results with LCQR and NQRC for estimating the survival time. The simulation results for the LCQR, LCQRC and NQRC are given in <xref ref-type="table" rid="table5">Table 5</xref>. It shows that LCQRC is better than that of LCRQ and NQRC. <xref ref-type="fig" rid="fig3">Figure 3</xref> summarize the simulation results for LCQRC5. It</p><p><xref ref-type="table" rid="table5">Table 5</xref>. Simulation results of <img src="2-1240111\5fb2e88c-6b2a-4264-8030-0225f5a1b7ae.jpg" /> for lung cancer data.<img src="2-1240111\f634c733-7d7e-4c69-a92c-e22c12f49e91.jpg" /></p><p>shows that the proposal is valid.</p></sec></sec><sec id="s4"><title>4. Conclusion</title><p>In this work, we have focused on the LCQR for nonparametric model with censored data and its nice theoretical properties have been proven. The proposed approaches are demonstrated by simulation examples and real data applications. In addition, we believe the method can be extended to varying coefficient model (see [<xref ref-type="bibr" rid="scirp.29912-ref7">7</xref>]).</p></sec><sec id="s5"><title>REFERENCES</title></sec><sec id="s6"><title>Appendix</title><p>Lemma 1. Assume assumption A1 hold. Then</p><p><img src="2-1240111\13e9086b-a33b-48d5-913c-084714e60534.jpg" /></p><p>where<img src="2-1240111\e0f870bc-6c33-4cf9-8bb9-53ed4bb7da60.jpg" />.</p><p>Proof. This follows directly from theorem 2.1 of [<xref ref-type="bibr" rid="scirp.29912-ref12">12</xref>].</p><p>Proof of Theorem 1 Let</p><p><img src="2-1240111\113528b5-31cb-4f74-9358-95eede494e1e.jpg" />,</p><p><img src="2-1240111\330fec91-ce70-498d-959b-6bb4bd517c35.jpg" />, <img src="2-1240111\839c76e2-cbfc-466b-a106-dc5c68a7acd4.jpg" />,</p><p><img src="2-1240111\392b790c-5000-4de8-ad74-447cc7fb287f.jpg" />,</p><p><img src="2-1240111\e1aff4a9-3475-408b-a9ac-ef85e1321664.jpg" /></p><p>Then <img src="2-1240111\0611e8a1-97c1-4df7-90dd-1b6e8298d092.jpg" /> is the minimizer of the following criterion:</p><p><img src="2-1240111\3ae1818a-8445-4043-9429-973601f91dab.jpg" /></p><p>where <img src="2-1240111\0f43e9fc-43c5-40b4-a121-67abe2c76d52.jpg" /> and<img src="2-1240111\8a812fb6-99de-49ac-887f-a86df6dfd787.jpg" />. To apply the identity ([<xref ref-type="bibr" rid="scirp.29912-ref13">13</xref>])</p><p><img src="2-1240111\1351b2ff-8f13-4e98-b85c-5882497187c6.jpg" /></p><p>we have</p><p><img src="2-1240111\593c02c7-a6ed-4d46-8617-b0daae766c1a.jpg" /></p><p>Since <img src="2-1240111\7cff4580-26b2-4420-8a60-9c33a890b23f.jpg" /> is any value sufficiently large to exceed all<img src="2-1240111\31564c21-ebbc-442d-bbd0-dbc118ac229b.jpg" />, <img src="2-1240111\914f14c0-7126-45d3-9911-69163fdfc22b.jpg" />and<img src="2-1240111\e2550f7e-8519-46c7-9d10-92bd96366ae9.jpg" />, then<img src="2-1240111\09cb1763-5fc7-44a7-acac-ff97701d6a42.jpg" />.</p><p>Denote<img src="2-1240111\007f3acb-8002-4f5c-8ea1-589b2ea98bb9.jpg" />, where</p><p><img src="2-1240111\1ad083c5-f61c-42a0-be4c-7b1dc82e4b46.jpg" />.</p><p><img src="2-1240111\34c19bf3-aed6-4d42-9b14-6a83efb60337.jpg" /></p><p>By the conditional independence of <img src="2-1240111\92976692-0b07-49d2-9f3a-20fcc025e0e3.jpg" /> and <img src="2-1240111\13ec8e6d-ab95-4ab2-bf1b-dec47b76ccc6.jpg" /> given<img src="2-1240111\177adbfe-22f2-4645-b5e5-0a572b1e3589.jpg" />, we have</p><p><img src="2-1240111\c4c21200-6ff3-421e-a274-56e1ef81fe22.jpg" /></p><p>Therefore,</p><p><img src="2-1240111\68739905-7d6f-4e40-9a67-973400a3a7e2.jpg" /></p><p>By Lemma 1, we have</p><p><img src="2-1240111\94d6a98f-ce9e-40dc-bdba-82fd89b36041.jpg" /></p><p>Then, we can obtain</p><p><img src="2-1240111\83fbea1f-2b0e-404d-8de2-883f8314a51e.jpg" /></p><p><img src="2-1240111\36785968-060c-4827-9410-a37441c8e140.jpg" /></p><p>So, we can obtain<img src="2-1240111\487c8d1d-9f40-411a-a5ad-2c4ce7fa92dd.jpg" />, then</p><p><img src="2-1240111\aa020b24-c8e2-475a-babe-0caf1285626c.jpg" /></p><p>where</p><p><img src="2-1240111\ddb2b2dd-1d28-458b-93c7-c3c96f715fc9.jpg" />.</p><p>Note that the error is symmetric, thus<img src="2-1240111\a3308708-faf3-4559-8ef7-6c3382b277a7.jpg" />, then it follows that</p><p><img src="2-1240111\b220cfd7-c36d-43dd-a89d-0cbf3e0ea641.jpg" /></p><p>Since<img src="2-1240111\84720e7f-4b0d-4cdb-a133-7d43b17660a3.jpg" />, then</p><p><img src="2-1240111\44a77ba5-0663-4a7f-80a8-b46cba24790a.jpg" /></p><p>So, we can obtain</p><p><img src="2-1240111\e2b92d8e-6356-4017-8d78-f02f099c2bb2.jpg" /></p><p>This completes the proof.</p></sec></body><back><ref-list><title>References</title><ref id="scirp.29912-ref1"><label>1</label><mixed-citation publication-type="other" xlink:type="simple">J. L. Powell, “Least Absolute Deviations Estimation for the Censored Regression Model,” Journal of Economet rics, Vol. 25, No. 3, 1984, pp. 303-325.  
doi:10.1016/0304-4076(84)90004-6</mixed-citation></ref><ref id="scirp.29912-ref2"><label>2</label><mixed-citation publication-type="other" xlink:type="simple">S. Portnoy, “Censored Regression Quantiles,” Journal of the American Statistical Association, Vol. 98, No. 464, 2003, pp. 1001-1012. doi:10.1198/016214503000000954</mixed-citation></ref><ref id="scirp.29912-ref3"><label>3</label><mixed-citation publication-type="other" xlink:type="simple">L. Peng and Y. Huang, “Survival Analysis with Quantile Regression Models,” Journal of the American Statistical Association, Vol. 103, No. 482, 2008, pp. 637-649.  
doi:10.1198/016214508000000355</mixed-citation></ref><ref id="scirp.29912-ref4"><label>4</label><mixed-citation publication-type="other" xlink:type="simple">H. J. Wang and L. Wang, “Locally Weighted Censored Quantile Regression,” Journal of the American Statistical Association, Vol. 104, No. 478, 2009, pp. 1117-1128.  
doi:10.1198/jasa.2009.tm08230</mixed-citation></ref><ref id="scirp.29912-ref5"><label>5</label><mixed-citation publication-type="other" xlink:type="simple">H. Zou and M. Yuan, “Composite Quantile Regression and the Oracle Model Selection Theory,” Annals of Statistics, Vol. 36, No. 3, 2008, pp. 1108-1126.  
doi:10.1214/07-AOS507</mixed-citation></ref><ref id="scirp.29912-ref6"><label>6</label><mixed-citation publication-type="other" xlink:type="simple">B. Kai, R. Li and H. Zou, “Local Composite Quantile Regression Smoothing: An Efficient and Safe Alternative to Local Polynomial Regression,” Journal of the Royal Statistical Society, Series B, Vol. 72, No. 1, 2010, pp. 49 69. doi:10.1111/j.1467-9868.2009.00725.x</mixed-citation></ref><ref id="scirp.29912-ref7"><label>7</label><mixed-citation publication-type="other" xlink:type="simple">B. Kai, R. Li and H. Zou, “New Efficient Estimation and Variable Selection Methods for Semiparametric Varying Coefficient Partially Linear Models,” Annals of Statistics, Vol. 39, No. 1, 2011, pp. 305-332. 
doi:10.1214/10-AOS842</mixed-citation></ref><ref id="scirp.29912-ref8"><label>8</label><mixed-citation publication-type="other" xlink:type="simple">R. Jiang, Z. G. Zhou, W. M. Qian and W. Q. Shao, “Single-Index Composite Quantile Regression,” Journal of the Korean Statistical Society, Vol. 3, No. 3, 2012, pp. 323-332. doi:10.1016/j.jkss.2011.11.001</mixed-citation></ref><ref id="scirp.29912-ref9"><label>9</label><mixed-citation publication-type="other" xlink:type="simple">R. Jiang, W. M. Qian and Z. G. Zhou, “Variable Selection and Coefficient Estimation via Composite Quantile Regression with Randomly Censored Data,” Statistics &amp; Probability Letters, Vol. 2, No. 2, 2012, pp. 308-317.  
doi:10.1016/j.spl.2011.10.017</mixed-citation></ref><ref id="scirp.29912-ref10"><label>10</label><mixed-citation publication-type="other" xlink:type="simple">A. Gannoun, J. Saracco, A. Yuan and G. Bonney, “Non Parametric Quantile Regression with Censored Data,” Scandinavian Journal of Statistics, Vol. 32, No. 4, 2005, pp. 527-550. doi:10.1111/j.1467-9469.2005.00456.x</mixed-citation></ref><ref id="scirp.29912-ref11"><label>11</label><mixed-citation publication-type="other" xlink:type="simple">C. L. Loprinzi, et al., “Prospective Evaluation of Prognostic Variables from Patient-Completed Questionnaires. North Central Cancer Treatment Group,” Journal of Clinical Oncology, Vol. 12, No. 3, 1994, pp. 601-607.</mixed-citation></ref><ref id="scirp.29912-ref12"><label>12</label><mixed-citation publication-type="other" xlink:type="simple">W. Gonzalez-Manteiga and C. Cadarso-Suarez, “Asymptotic Properties of a Generalized Kaplan-Meier Estimator with Some Applications,” Journal of Nonparametric Sta tistics, Vol. 4, No. 1, 1994, pp. 65-78.  
doi:10.1080/10485259408832601</mixed-citation></ref><ref id="scirp.29912-ref13"><label>13</label><mixed-citation publication-type="other" xlink:type="simple">K. Knight, “Limiting Distributions for L1 Regression Estimators under General Conditions,” Annals of Statistics, Vol. 26, No. 2, 1998, pp. 755-770. 
doi:10.1214/aos/1028144858</mixed-citation></ref></ref-list></back></article>