Adolescent idiopathic scoliosis is defined as spinal lateral curvature Cobb angle > 10˚ accompanied with vertebral rotation without definite congenital, neurological or organic etiology, mainly occurring in children aged 10 - 18 years during rapid growth and development [1]. In recent decades, long-term sedentary study, incorrect sitting posture and insufficient physical activity significantly increase AIS incidence in Chinese primary and secondary school students, which has become a severe public health problem threatening adolescent physical development [2].

For mild and moderate AIS without surgical indications, non-invasive conservative exercise intervention is the first-line recommended plan by International Scoliosis Society guidelines [3]. Standardized exercise therapy (SET) for adolescent idiopathic scoliosis is defined as evidencebased, protocol-driven conservative rehabilitation that targets three-dimensional spinal deformity correction, asymmetric muscle balancing, and postural proprioception retraining. The most internationally recognized systems include Schroth method, SEAS (Scientific Exercises Approach to Scoliosis), and Dobomed. These modalities focus highly on spinal biomechanical remodeling, asymmetric muscle strength training and three-dimensional rotational correction, but generally ignore adolescent psychological burden, appearance anxiety and low self-esteem caused by body deformity [4]. Single mechanical correction easily leads to low adherence, training boredom and poor long-term prognosis, forming a vicious cycle of physical deformity-negative emotion-muscle tension aggravation [5].

Traditional Chinese health preservation philosophy adheres to holistic view of man as an organic whole, unity of form, qi and spirit, preventing disease before onset and regulating both body and mind, which is naturally consistent with whole-course adolescent rehabilitation demand [6]. As the representative traditional TCM health qigong created by Hua Tuo, Wuqinxi imitates tiger, deer, bear, ape and bird movements, integrates body stretching, abdominal respiration, meridian regulation and mental calming. Existing clinical evidence has verified its efficacy in improving spinal mobility, relieving paraspinal muscle spasm and improving emotional state [7].

At present, domestic and overseas studies mostly compare single exercise efficacy, lack systematic theoretical interpretation from traditional regimen culture, and rarely conduct in-depth humanistic research on coordinated physical correction and psychological growth. Therefore, this paper constructs an integrated rehabilitation model of Wuqinxi combined with standardized scoliosis exercise therapy, analyzes internal synergistic mechanism under traditional health preservation theory, and explores its unique humanistic value in adolescent whole-life growth health management, so as to provide reference for high-quality SCI-related comprehensive traditional-medicine rehabilitation research.

High-quality clinical evidence supporting the combined regimen of Wuqinxi and standardized scoliosis-specific exercise for adolescent idiopathic scoliosis remains scarce. Existing published studies are mostly small-sample pilot investigations with notable heterogeneity in intervention duration, training intensity and patient inclusion criteria. Well-designed multi-center, long-term randomized controlled trials are currently unavailable to validate its definitive therapeutic efficacy. Furthermore, unified operational specifications tailored to AIS have not yet been formulated, and the underlying neuroendocrine and central neuromodulatory mechanisms of mind-body exercise require further in-depth exploration. Insufficient large-sample multi-center randomized controlled trials, lack long-term 2 - 5 years growth follow-up data, non-unified standardized Wuqinxi AIS special training paradigm, and insufficient in-depth exploration of molecular neuroendocrine mechanism of psychological emotion regulation [22].

In future high-level SCI research directions:

(1) Carry out evidence-based big data clinical trials to verify long-term curative stability;

(2) Establish age-stage scoliosis specialized five-animal exercise standardized operation procedure;

(3) Explore brain function imaging and inflammatory factor pathways of mind-body co-regulation;

(4) Popularize school-family integrated traditional exercise rehabilitation mode nationwide.

Under the guidance of traditional Chinese holistic mind-body health preservation theory, Wuqinxi was integrated with international standardized scoliosis-specific exercise therapy. Drawing on existing mechanistic evidence and preliminary AIS data, this integrated approach is proposed to provide complementary benefits in biomechanical correction, neuromuscular remodeling, and psychological modulation [23][24]. Consequently, it holds the potential to mitigate curve progression, improve trunk function, alleviate emotional distress, and enhance treatment compliance [25]. This combined therapeutic regimen can effectively retard the progression of spinal curvature, ameliorate somatic appearance dysfunction, alleviate inferiority and anxiety symptoms among adolescents, and markedly enhance rehabilitation compliance [26]-[28]. Furthermore, this integrative strategy embodies profound heritage value of traditional Chinese health culture, people-oriented medical humanistic connotation and far-reaching significance for long-term adolescent physical and mental health development [21][23][27]. Such a traditional-modern holistic rehabilitation paradigm provides a novel theoretical innovation orientation and a safe, non-invasive clinical option for conservative intervention of adolescent idiopathic scoliosis worldwide, which warrants further in-depth high-quality mechanistic investigations and international clinical popularization [29][30].