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  <front>
    <journal-meta>
      <journal-id journal-id-type="publisher-id">Oalib</journal-id>
      <journal-title-group>
        <journal-title>Open Access Library Journal</journal-title>
      </journal-title-group>
      <issn pub-type="epub">2333-9721</issn>
      <issn pub-type="ppub">2333-9705</issn>
      <publisher>
        <publisher-name>Scientific Research Publishing</publisher-name>
      </publisher>
    </journal-meta>
    <article-meta>
      <article-id pub-id-type="doi">10.4236/oalib.1115446</article-id>
      <article-id pub-id-type="publisher-id">Oalib-151864</article-id>
      <article-categories>
        <subj-group>
          <subject>Article</subject>
        </subj-group>
        <subj-group>
          <subject>Biomedical</subject>
          <subject>Life Sciences</subject>
          <subject>Business</subject>
          <subject>Economics</subject>
          <subject>Chemistry</subject>
          <subject>Materials Science</subject>
          <subject>Computer Science</subject>
          <subject>Communications</subject>
          <subject>Earth</subject>
          <subject>Environmental Sciences</subject>
          <subject>Engineering</subject>
          <subject>Medicine</subject>
          <subject>Healthcare</subject>
          <subject>Physics</subject>
          <subject>Mathematics</subject>
          <subject>Social Sciences</subject>
          <subject>Humanities</subject>
        </subj-group>
      </article-categories>
      <title-group>
        <article-title>Occult Femoral Neck Stress Fracture Presenting as Knee Pain: A Diagnostic Challenge in Primary Care</article-title>
      </title-group>
      <contrib-group>
        <contrib contrib-type="author" corresp="yes">
          <name name-style="western">
            <surname>Alhiasat</surname>
            <given-names>Zayd</given-names>
          </name>
          <xref ref-type="aff" rid="aff1">1</xref>
        </contrib>
        <contrib contrib-type="author">
          <name name-style="western">
            <surname>Mahd</surname>
            <given-names>Sandy</given-names>
          </name>
          <xref ref-type="aff" rid="aff2">2</xref>
        </contrib>
      </contrib-group>
      <aff id="aff1"><label>1</label> Department of Orthopaedics, Emergency County Hospital Bihor, Oradea, Romania </aff>
      <aff id="aff2"><label>2</label> Department of Family Medicine, Emergency County Hospital Bihor, Oradea, Romania </aff>
      <author-notes>
        <fn fn-type="conflict" id="fn-conflict">
          <p>The authors declare no conflict of interest.</p>
        </fn>
      </author-notes>
      <pub-date pub-type="epub">
        <day>05</day>
        <month>06</month>
        <year>2026</year>
      </pub-date>
      <pub-date pub-type="collection">
        <month>06</month>
        <year>2026</year>
      </pub-date>
      <volume>13</volume>
      <issue>06</issue>
      <fpage>1</fpage>
      <lpage>6</lpage>
      <history>
        <date date-type="received">
          <day>07</day>
          <month>05</month>
          <year>2026</year>
        </date>
        <date date-type="accepted">
          <day>12</day>
          <month>06</month>
          <year>2026</year>
        </date>
        <date date-type="published">
          <day>15</day>
          <month>06</month>
          <year>2026</year>
        </date>
      </history>
      <permissions>
        <copyright-statement>© 2026 by the authors and Scientific Research Publishing Inc.</copyright-statement>
        <copyright-year>2026</copyright-year>
        <license license-type="open-access">
          <license-p> This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/4.0/">https://creativecommons.org/licenses/by/4.0/</ext-link> ). </license-p>
        </license>
      </permissions>
      <self-uri content-type="doi" xlink:href="https://doi.org/10.4236/oalib.1115446">https://doi.org/10.4236/oalib.1115446</self-uri>
      <abstract>
        <p>Femoral neck stress fractures (FNSFs) are uncommon injuries that may present with atypical and misleading symptoms, resulting in delayed diagnosis. Although classically associated with athletes and military personnel, these fractures can also occur in non-athletic individuals exposed to repetitive mechanical stress. We report the case of a 35-year-old male who presented with isolated knee pain without antecedent trauma. Initial clinical evaluation suggested primary knee pathology, and knee radiographs were unremarkable. Persistent symptoms and abnormal findings on hip examination prompted extension of the diagnostic workup to the hip. Magnetic resonance imaging (MRI) revealed an occult nondisplaced compression-side femoral neck stress fracture. The patient was managed conservatively with protected weight-bearing and close orthopaedic follow-up, resulting in complete recovery. This case highlights the importance of considering proximal sources of pain when evaluating unexplained knee symptoms. MRI is particularly useful when persistent symptoms and examination findings raise suspicion for occult proximal pathology despite negative radiographs.</p>
      </abstract>
      <kwd-group kwd-group-type="author-generated" xml:lang="en">
        <kwd>Femoral Neck Stress Fracture</kwd>
        <kwd>Knee Pain</kwd>
        <kwd>Occult Fracture</kwd>
        <kwd>Magnetic Resonance Imaging</kwd>
        <kwd>Primary Care</kwd>
        <kwd>Orthopaedics</kwd>
      </kwd-group>
    </article-meta>
  </front>
  <body>
    <sec id="sec1">
      <title>1. Introduction</title>
      <p>Femoral neck stress fractures (FNSFs) are rare but potentially serious injuries caused by repetitive subthreshold loading that exceeds the bone’s capacity for remodeling. Although commonly reported in athletes and military personnel, they may also occur in the general population without obvious predisposing factors [<xref ref-type="bibr" rid="B1">1</xref>].</p>
      <p>FNSFs are frequently underdiagnosed because of their insidious onset and nonspecific presentation. Patients commonly report groin or hip pain; however, referred pain to the thigh or knee may occur and contribute to diagnostic confusion [<xref ref-type="bibr" rid="B2">2</xref>]. Occult fractures, defined as fractures not visible on plain radiographs, further complicate early diagnosis and often require advanced imaging modalities such as magnetic resonance imaging (MRI) for confirmation [<xref ref-type="bibr" rid="B3">3</xref>].</p>
      <p>In primary care settings, isolated knee pain is often attributed to local pathology, potentially delaying recognition of proximal causes. Failure to diagnose FNSFs early may result in fracture displacement, nonunion, or avascular necrosis of the femoral head [<xref ref-type="bibr" rid="B4">4</xref>]. This case report describes an unusual presentation of an occult femoral neck stress fracture manifesting solely as knee pain and emphasizes the importance of comprehensive clinical assessment and appropriate imaging.</p>
    </sec>
    <sec id="sec2">
      <title>2. Case Presentation</title>
      <p>A 35-year-old previously healthy male presented to the family medicine clinic with a 2-week history of progressive right knee pain. The pain was insidious in onset, worsened with weight-bearing, and was not associated with trauma, swelling, locking, or instability. Initial differential diagnoses included patellofemoral pain syndrome, meniscal pathology, tendinopathy, early degenerative disease, and referred pain from the hip or lumbar spine. The patient reported recent increased physical activity related to manual labor but denied participation in sports.</p>
      <p>The patient denied smoking, excessive alcohol consumption, corticosteroid use, prior stress fractures, endocrine or metabolic bone disease, nutritional deficiencies, or recent weight loss. There was no known history of osteoporosis or chronic systemic illness.</p>
      <p>Physical examination demonstrated a normal right knee with full range of motion, no effusion, no joint-line tenderness, and no ligamentous instability. However, discomfort was elicited during internal rotation of the right hip, raising suspicion for a proximal source of pain and prompting extension of the diagnostic workup to the hip. Neurovascular examination was otherwise unremarkable.</p>
      <p>Initial plain radiographs of the right knee were normal. Conservative management with nonsteroidal anti-inflammatory drugs (NSAIDs), activity modification, and rest was initiated.</p>
      <p>Due to persistent symptoms after 10 days and lack of clinical improvement, further evaluation was undertaken. Radiographs of the pelvis and hip were inconclusive and showed no visible fracture. Because persistent symptoms and hip examination findings remained unexplained despite negative radiographs, MRI was obtained as the preferred imaging modality for suspected occult femoral neck stress fractures due to its high sensitivity for early bone stress injury and bone marrow edema [<xref ref-type="bibr" rid="B5">5</xref>][<xref ref-type="bibr" rid="B7">7</xref>].</p>
      <p>MRI of the right hip revealed a nondisplaced inferomedial (compression-side) femoral neck stress fracture associated with surrounding bone marrow edema [<xref ref-type="bibr" rid="B5">5</xref>].</p>
      <fig id="fig1">
        <label>Figure 1</label>
        <graphic xlink:href="https://html.scirp.org/file/1115446-rId13.jpeg?20260615120438" />
      </fig>
      <p><bold>Figure 1.</bold> Coronal fat-suppressed T2-weighted MRI of the right hip demonstrating a linear hypointense fracture line (red arrow) at the superolateral aspect of the femoral neck with surrounding bone marrow edema (white arrow), consistent with an occult nondisplaced femoral neck stress fracture.</p>
      <p>Following diagnosis, the patient was urgently referred to orthopaedics (see <xref ref-type="fig" rid="fig1">Figure 1</xref><xref ref-type="fig" rid="fig1">Figure 1</xref>). Management consisted of strict non-weight-bearing with crutches for 6 weeks and serial clinical and radiographic follow-up. Repeat radiographs obtained at 6 weeks demonstrated interval fracture healing without displacement. Progression to partial and subsequently full weight-bearing was guided by complete resolution of pain during ambulation and evidence of radiographic healing. Surgical intervention was not required because the fracture remained stable throughout follow-up.</p>
      <p>At 3-month follow-up, the patient had resumed normal daily activities without pain or functional limitation.</p>
    </sec>
    <sec id="sec3">
      <title>3. Discussion</title>
      <sec id="sec3dot1">
        <title>3.1. Atypical Presentation and Referred Pain</title>
        <p>Femoral neck stress fractures represent a diagnostic challenge because of their rarity and frequently atypical clinical presentation. Although traditionally associated with athletes, increasing evidence suggests these fractures may also occur in non-athletic individuals exposed to repetitive mechanical stress or sudden increases in activity levels [<xref ref-type="bibr" rid="B6">6</xref>].</p>
        <p>The most notable aspect of this case was the presentation with isolated knee pain. Referred pain from the hip to the knee is explained by shared innervation through the femoral and obturator nerves, which may mislead clinicians toward a primary knee disorder [<xref ref-type="bibr" rid="B2">2</xref>].</p>
        <p>Recent literature has emphasized that occult proximal femoral fractures may mimic a variety of musculoskeletal conditions, contributing to significant diagnostic delay [<xref ref-type="bibr" rid="B3">3</xref>]. Consequently, clinicians should maintain a high index of suspicion when symptoms persist despite appropriate initial management and imaging findings do not correlate with the clinical presentation.</p>
      </sec>
      <sec id="sec3dot2">
        <title>3.2. Diagnostic Challenges and Imaging</title>
        <p>Plain radiographs are typically the first-line imaging modality for musculoskeletal pain but have limited sensitivity for early or nondisplaced stress fractures. Several studies have demonstrated that occult fractures may not be visible on initial radiographs, particularly during the early stages of injury [<xref ref-type="bibr" rid="B5">5</xref>][<xref ref-type="bibr" rid="B7">7</xref>].</p>
        <p>MRI is considered the gold standard for the diagnosis of occult femoral neck stress fractures because it provides excellent sensitivity for detecting both fracture lines and associated bone marrow edema. Early MRI evaluation enables prompt diagnosis and treatment before fracture progression or displacement occurs.</p>
        <p>Early recognition is essential because delayed diagnosis may result in fracture displacement requiring surgical fixation and may increase the risk of avascular necrosis, nonunion, and long-term disability [<xref ref-type="bibr" rid="B4">4</xref>].</p>
      </sec>
      <sec id="sec3dot3">
        <title>3.3. Clinical Implications in Family Medicine</title>
        <p>From a family medicine perspective, this case underscores the importance of holistic musculoskeletal assessment. Evaluation of adjacent joints and consideration of referred pain patterns are critical when clinical findings do not fully explain the patient’s symptoms.</p>
        <p>Persistent pain despite conservative treatment should prompt reconsideration of the diagnosis and further investigation. In patients with unexplained knee pain and subtle hip examination findings, proximal pathology should remain within the differential diagnosis.</p>
      </sec>
      <sec id="sec3dot4">
        <title>3.4. Orthopaedic Perspective and Management</title>
        <p>Management of femoral neck stress fractures depends largely on fracture location, stability, and risk of displacement. Compression-side fractures occurring along the inferomedial femoral neck are generally considered biomechanically stable and may be managed conservatively with protected weight-bearing and close radiographic follow-up.</p>
        <p>In contrast, tension-side fractures located on the superior aspect of the femoral neck carry a substantially greater risk of displacement and frequently require surgical fixation [<xref ref-type="bibr" rid="B6">6</xref>].</p>
        <p>Early diagnosis and appropriate management are associated with favorable outcomes and significantly reduced rates of complications such as avascular necrosis and nonunion [<xref ref-type="bibr" rid="B6">6</xref>].</p>
      </sec>
      <sec id="sec3dot5">
        <title>3.5. Importance of Early Recognition</title>
        <p>Delayed diagnosis of femoral neck stress fractures remains a major clinical concern. Multiple reports describe cases in which atypical symptoms resulted in diagnostic delay and progression of injury [<xref ref-type="bibr" rid="B3">3</xref>].</p>
        <p>This case highlights the importance of maintaining clinical suspicion for proximal pathology in patients with persistent unexplained knee pain, particularly when physical examination findings extend beyond the knee joint itself.</p>
      </sec>
    </sec>
    <sec id="sec4">
      <title>4. Conclusions</title>
      <p>Occult femoral neck stress fractures may rarely present with atypical symptoms such as isolated knee pain, potentially delaying diagnosis. Clinicians should consider proximal pathology when persistent symptoms and examination findings are not adequately explained by knee pathology alone.</p>
      <p>MRI is particularly valuable when ongoing symptoms and clinical suspicion raise concern for an occult proximal source despite negative radiographs. Early recognition and appropriate multidisciplinary management are essential to prevent complications and optimize patient outcomes.</p>
    </sec>
    <sec id="sec5">
      <title>5. Limitations</title>
      <p>This report describes a single clinical case, limiting the generalizability of the findings. In addition, long-term follow-up was not available to evaluate for late complications such as avascular necrosis or recurrent stress injury.</p>
    </sec>
    <sec id="sec6">
      <title>Acknowledgements</title>
      <p>No external funding was received for this study.</p>
    </sec>
    <sec id="sec7">
      <title>Patient Consent and Ethics Statement</title>
      <p>Written informed consent was obtained from the patient for publication of this case report and accompanying images. Ethical approval was not required according to institutional guidelines for single case reports.</p>
    </sec>
    <sec id="sec8">
      <title>Author Contributions</title>
      <p>[Sandy M]: Conceptualization, patient evaluation, manuscript drafting.</p>
      <p>[Zayd A]: Orthopaedic management, literature review, manuscript revision.</p>
    </sec>
    <sec id="sec9">
      <title>AI Use Statement</title>
      <p>No artificial intelligence tools were used in the preparation of this manuscript.</p>
    </sec>
  </body>
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