Sickle cell disease is a real public health problem with a high prevalence of major SS forms [1].

Clinically, it manifests as acute and chronic hemolytic anemic episodes, vaso -occlusive crises (VOCs), and infectious syndromes. and multiple functional degenerations [2].

Although it is a chronic disease, it is potentially serious, as it is characterized by the occurrence of infectious, ischemic, and anemic complications: Vaso -occlusive crises, acute chest syndrome, priapism, strokes, neurosensory disorders, liver, splenic, and renal disorders, and acute vertigo or sudden deafness, cardiopulmonary disorders, gallstones, ulcers cutaneous, osteonecrosis which may affect functional and vital prognosis [2][3].

These complications require a thorough diagnostic approach and prompt, appropriate management. effective and control of triggering factors to thus circumvent the high risk of morbidity and mortality to which they expose sickle cell patients [3].

In the United States, approximately 100,000 people carry sickle cell disease, causing multi-system morbidities, including a risk of early death [4].

In France in 2014, 485 major sickle cell syndromes (SDM) were detected [5].

In Africa, the prevalence of sickle cell trait varies between 1 and 45% depending on the country [1]. Hence 500 000 children are born with the sickle cell disease of which 60% has 80% die before the age of 5 due to lack of early screening and adequate care [7].

In Cameroon, out of a population of approximately 15 million, 25 to 30% have sickle cell disease, of which 2 to 3% are homozygous [2].

Gabon is located in an area of very high prevalence: 24% of subjects carry the hemoglobin S (HbS) trait and the number of homozygous patients is estimated at 2.2% of the population [8].

At Benign there prevalence East of 22.3%, of which 4% are homozygous [9].

At Togo, the prevalence East of 16.1%, with 3 has 5% of shapes major [7]. In Mali, the prevalence is estimated at 12% with 3% homozygous [10]

In Senegal, the prevalence of hemoglobin S is estimated at 10%, of which 1% are homozygous forms [11].

In Guinea, Camara E et al. in 2019 found 7.8% of major sickle cell syndrome (MSS) [12], Diakité M et al. in 2020 have reported a sickle cell prevalence of 12.6% in the Hematology department of the Ignace Deen University Hospital in Conakry. [13]

But these different studies have addressed the prevalence along with certain characteristics but have rarely focused on assessing the quality of care, thus motivating the present work.

Evaluate the quality of care children sickle cell Children aged 0 to 15 years in the Pediatrics Department of the University Hospital Ignace Deen from Conakry (Guinea).

Kindandduration study: It was of a study trans of kind description of a duration of 6 month from December 15, 2020 to May 14 2021.

Population study: She was consisting of all patients hospitalized sickle cell patients, and all service providers having a child with sickle cell disease was seen for consultation.

Criteria of selection:

- Inclusion criteria: This study included all hospitalized sickle cell patients aged 0 to 15 years, regardless of sex or origin, diagnosed based on the Emmel test/hemoglobin electrophoresis, who received treatment. and all the service providers who have taken taking care of a child with sickle cell disease during the study period.

- Exclusion criteria:The following were not included in this. This study excludes all patients diagnosed with pathologies other than sickle cell disease and all healthcare providers. not being present during the study period. But also non-consenting parents or guardians.

Fashion of recruitment: Recruitment was exhaustive and included all sickle cell patients and all providers meeting the selection criteria during our study period.

The quality of care was assessed based on ten (10) elements, namely:

1) The level of satisfaction of parents/guardians with respect tothe reception: this concerns the communication between the health worker and the mother/guardian during the consultation:

Welcome (Good, (acceptable, bad)THE advice data (Good, acceptable, bad)THE appointment of follow up of the child (Yes or not)Information of diagnosis of the child by the agent of health: Yes or No

2) Accessibility geographical considerations included:

THE time put for arrive at center: lower has 30 minutes or superior at 30 minutesMeans used for arrive at center, as: foot, transportation shared transport, motorcycle taxi, dugout canoe, personal vehicle…There residence: as area urban (Conakry) or rural (out Conakry)

3) Parents’/guardians’ knowledge of sickle cell disease:

Forms of sickle cell disease include: SS, AS, SC, S/β-thalassemia…THE fashion of transmission of there sickle cell disease: hereditary, born knows not,Signs of sickle cell disease in children aged 0 to 15 years: dactylitis, abdominal pain, pain bone marrow, jaundice, anemia, dizziness, physical asthenia, dyspnea, chest pain, edema of the limbs or other symptoms.Factors triggering sickle cell crises in children aged 0 to 15 years: temperature change, stress, dehydration, infection, hypoxia, cold, intense physical exercise;

4)Legal recourse in case of a sickle cellcrisis.Thiswill involve: health structure or self-medication (pharmaceutical or traditional medicines).

5)There biology:

Blood count: is the quantitative and qualitative analysis of the formed elements of blood.Emmel test or sickle cell test: Examination of the blood smear allowing observation of sickle-shaped red blood cells.Hemoglobin electrophoresis: is a method of separating electrically charged particles by differential migration under the action of an electric field.

The judgment was based on financial and geographical accessibility conditions.

6)Treatment receipts:

Acid folicPain relievers or anti-inflammatories: paracetamol, tramadol diclofenac, ibuprofenHydroxyurea or hydroxycarbamide is a particularly important molecule involved in the treatment of sickle cell anemia; it stimulates the synthesis of fetal hemoglobin (HbF), composed of 2 alpha chains and 2 gamma chains.Transfusion blood: Yes Or NoAntibioticHyperhydration: Salt Serum 0.9%, Glucose Serum 5%, Bicarbonate Serum 1.4%;

7)Identification of provider:

Qualification: She will concern THE title of staff either pediatrician, currently undergoing specialist training, general practitioner or intern.

8)Organization of service: She will wear

Permanent service 24 hours on 24 hours;Kits of PEC of the EMERGENCIES at the house of THE sickle cell during the guard;Reagents and diagnostic tests ( Emmel’s T) for sickle cell disease during guard duty, hemoglobin electrophoresis;

9)Availability in materials, reagents, drugs: they have door on:

Endowment in medications and reagents regular.Materials: Gloves, lab coat, watch or clock, pen /marker or pencil, microscope, TE kit, Hemoglobin electrophoresis, oxygen cylinder with child mask, child blood pressure monitor, stethoscope, scale, thermometer.

10)Tasks and actions of the consultant: they have door regarding staff behavior in the following actions:

To welcome GOOD there mother of the childPay attentionTalk with kindnessDate of beginning of the signsTreatment priorTake THE parametersRespect there confidentiality of there consultationInform the mother of diagnosis of the childExplain the use of the drugsExplain THE effects secondary of the drugsSe to reassure of there understanding of the mother by report to the treatmentAdvise there mother to increase THE liquids during there diseaseExplain when to come back immediatelyExplain when to come back for their visit of follow upIdentify the signs of gravity of there sickle cell disease

11)Availabilityandfunctionality of the infrastructure:he it was:

Room of consultationRooms hospitalizationRoom of guardLaboratoryPharmacy

Note: These different items have summer judged according to their terms in Good, acceptable, and bad.

Good: when THE observed patterns are superior or equal has 75%. Acceptable: when the observed conditions are between 50 and 74%; Poor: when the observed values are lower 50%.

Variables, statistical studies

Our variables were both quantitative and qualitative.

The data was collected through direct interviews with parents/guardians and often older children, but also through careful analysis of files for additional information.

Then they were entered and analyzed using Excel, Word and Statistics Package for Social Science (SPSS) version 21.0.

Regarding the ethical issue, the anonymity and confidentiality of our patients were respected and the free informed consent, written or verbal, of the patients was strictly required; thus, the data collected is used only for scientific purposes.

Our study included 63 patients, of whom 61 had sickle cell disease and two (2) were excluded due to lack of consent from their guardians. Their sociodemographic characteristics (Table 1) show a mean age of 6.38 years ± 4.02 years. 59.02% were female and 40.98% male, with a sex ratio of 0.69. The 1-5 year age group was the most represented (49.18%). The study involved 29 healthcare professionals: 5 pediatricians, 4 residents in specialization training, 6 general practitioners, 4 interns, and 10 nurses. They comprised 14 men (48.27%) and 15 women (51.72%), with a sex ratio of 0.9 and a mean age of 33 years.

Table 1.Distribution of children with sickle cell disease according to sociodemographic data at service of pediatrics of the Ignace Deen University Hospital of 15 December 2020 at May 14, 2021.

Age AVERAGE 6.38 ± 4.02 Extreme Years 1 and 15 years; Sex ratio = 0.69.

The most common reason for consultation was fever (100%) (Table 2). First-line treatment was medical in 67.21% of cases, predominantly the combination of paracetamol and ibuprofen (34.43%) (Table 3). Treatments received were: 100% hyperhydration and analgesics, 96.72% antibiotics, and 80.33% blood transfusions (Table 4). Geographic accessibility to the Pediatric Department was fair (52.46%) (Table 5).

Table 2.Frequency according to the reasons for consultations for children with sickle cell disease at service of pediatrics of the Ignace Deen University Hospital 15 December 2020 at May 14, 2021.

Table 3.Distribution according to appeal of treatment of first intention parents of children with sickle cell disease in the pediatric department of the Ignace Deen University Hospital in Conakry.

Table 4.Distribution according to the treatment received by THE Children with sickle cell disease in the pediatric department of the Ignace Deen University Hospital in Conakry.

Table 5.Distribution according to accessibility geographical at service of pediatrics at the Ignace Deen University Hospital in Conakry.

We had achieved a study trans of kind description of a duration of 6 month from December 15, 2020 to May 14 2021.

The objective of this study was to evaluate the quality of care children sickle cell from 0 to 15 years old in the Pediatrics department of the Ignace Deen University Hospital in Conakry.

In our study, age average (6.38) was close of the one of Barry IK coll. In Guinea in 2019 [14] who found an average age of 7 years.

The female predominance found in our study (59 0.02%; 0.69) is contrary to those reported by Diakité AA et al. in 2019 in Mali [15] and Dodo R et al. in 2018 in Benin [16] who respectively had a male/female sex ratio of 1.46 and 1.55.

This could be explained by the predominance of women in the general Guinean population.

The predominance of school-aged children (63.93%) differs from that of Diakité M et al. Guinea in 2020 [15] and similar to that of Dodo R and colleagues. In 2018 in Benin [17] which found respectively 42% and 55.6% of children enrolled in school. This could be explained by the fact that young teenagers would be more predisposed to sickle cell crises.

The majority of our patients reside in the capital (80.33%) in Cameroon, which corresponds to that of Chetcha CB et al. in 2018 [3] and Diakité M and colleagues in Guinea in 2020, in his doctoral thesis in medicine [13] which reported that 82.60% and 82.67% respectively came from the capital city. This could be explained by the proximity of the Ignace Deen Hospital, which is located in the heart of Conakry, and that Other users often come by referral.

In our study, approximately half of the parents (45.90%) had no knowledge of methods for preventing seizures.

This result could be explained by the fact that user education is not adequate and more effort is needed to raise public awareness about the disease in general and about the factors triggering sickle cell crises in particular.

The first resort used by patients during crises (67.21%) is comparable to that of Diallo MY in his doctoral thesis in 2013 in Mali [17], and Seck I et al. [18] who found medical treatment rates of 78.26% and 88.6% respectively. This could be explained by educating users to go to the hospital at the first signs.

The technical competence found in our study was good (63.64%), acceptable (18.18%), and poor (18.18%), which is in some places comparable to that of Diallo. MY in Mali in 2013 [17], which found 66.7% respectively; 27.8% and 5.6%. Generally, in our structures, the technical competence of the service providers is unequivocal but can encounter a problem related to financial accessibility because the costs are borne by the families.

This study reveals that the quality of care for children with sickle cell disease is complex. While it was good and acceptable in the areas addressed, particularly the organization of care and access to supplies and medications, further efforts are needed to improve this quality and ensure the sustainability of these achievements. This includes the implementation of universal health coverage for these chronic congenital diseases to alleviate the burden of care on families.

All authors contributed to the development of this article. The authors declare that they have read and approved the manuscript.