3.1.1. Sociodemographic Characteristics of Surveyed Hemodialysis Patients

The study population consisted of 17 patients with an average age of 55.7 years ± 13.7 years. The most affected age group was 56 to 65 years (35.3%). It was less significant in patients aged 46 to 55 years (17.6%). The surveyed population was predominantly male, with a rate of 64.7%. The majority of patients resided in N’Djamena and its suburbs. Most of them, 52.9%, were educated, with 29.82%, 12.47%, and 10.61% having secondary, higher, and primary education levels, respectively, compared to 47.1% who were not educated. Access to dialysis is free for all patients thanks to public funds, but only 11.8% of our patients benefit from health insurance for purchasing adjuvant medications for hemodialysis. Regarding profession, 29.4% of our mothers were housewives. Regardless of gender, 17.6% and 11.8% were merchants and teachers, respectively (Table 1).

Table 1. Sociodemographic characteristics of surveyed patients.

3.1.2. Etiologies of Kidney Failure or Causal Nephropathy

Hypertension (48.13%) and diabetes (25.12%) were the predominant causes of CKD. Other etiologies included infection (14.25%), side effects of medication (7.65%), and drepanocytose (4.85%) (Figure 1).

Figure 1. Distribution of patients according to the underlying nephropathy (%).

3.1.3. Duration of Dialysis

The majority of patients (47%) had been on dialysis for 5 - 10 years, while 30% had undergone treatment for 3 - 5 years (Figure 2).

Figure 2. Distribution of dialysis duration among patients.

3.2.1. MNA-SF Score Parameters

Nutritional status assessment according to the MNA-SF score was based on six parameters:

Food Intake andAnorexia:Figure 3 shows that 82.4% (14 patients) had not decreased their food intake. As for Table 2, it reveals that most of our patients were not anorexic, 52.9% of cases after one month, but after three months, 60.7% had severe anorexia and 30.1% had moderate anorexia.

Figure 3.Distribution according to food intake.

Table 2. Distribution according to the evolution of anorexia.

Recent Weight Loss:Table 3 reveals that 4 patients (23.5%) had recent weight loss > 3 kg.

Table 3. Distribution according to recent weight loss.

Mobility:Table 4 shows that 52.9% (9 patients) left their homes.

Table 4. Distribution according to mobility.

Figure 4. Distribution according to the presence of an acute illness.

Figure 5. Distribution according to the presence of a neuropsychiatric pathology.

Acute Illness or Stress: According to Figure 4, the majority of patients did not suffer from acute illness or stress.

Neurological Problems:Figure 5 shows that 88% of patients had no neurological problems.

Body Mass Index:Figure 6 reveals that nearly half of our patients had a BMI < 19 kg/m² (8 patients or 47%) while 11.8% tended toward being overweight.

Figure 6. Distribution according to the presence of a neuropsychiatric pathology.

3.2.2. Nutritional Status according to MNA-SF Score

MNA results showed that 47% of hemodialysis patients are malnourished, 41.14% are at risk of malnutrition, and only 11.76% have satisfactory nutritional status (Table 5).

Table 5.Nutritional assessment according to the Mini Nutritional Assessment score.

The main objective of the study was to assess the nutritional status of patients with chronic kidney disease followed at the University Hospital. The sociodemographic profile of kidney failure patients was first determined.

This study illuminates a profound and critical public health crisis within Chad’s healthcare system, revealing an alarmingly high prevalence of malnutrition among chronic hemodialysis patients that borders on an epidemic within this vulnerable cohort. Our data indicate a devastating reality where 47% of patients are classified as malnourished and a further 41.2% are at serious risk, meaning that nearly 90% of the individuals reliant on hemodialysis for survival are grappling with significant nutritional deficits [7][8]. This figure is not an outlier but rather a grim confirmation of the well-documented, yet persistently unaddressed, crisis across Sub-Saharan Africa, where malnutrition afflicts 30 to 50% of the hemodialysis population, underscoring a catastrophic failure to integrate nutritional support as a cornerstone of comprehensive renal care. The demographic profile of our cohort, with a mean age of 55.7 years, aligns with findings from neighbouring Ghana and Nigeria, but presents a stark contrast to the younger patient populations in the Maghreb and the significantly older demographics typical of Western nations [9]-[12]. This divergence is not merely statistical; it reflects deeper, systemic issues, including the earlier onset of End-Stage Renal Disease (ESRD) due to poorly controlled hypertension and diabetes, lower overall life expectancy, and the immense burden of disease placed upon the socially and economically active segment of the population. A critical, and perhaps the most debilitating, factor exacerbating this medical crisis is the profound socioeconomic precarity of the patients. The vast majority lack any form of health insurance, and while the government’s coverage of dialysis costs is a crucial intervention, it is rendered insufficient when patients cannot afford the essential concomitant medications, such as phosphate binders and erythropoietin, or the specific, and often more costly, nutrient-dense foods required to sustain them on dialysis [13][14]. This financial abyss often forces patients into impossible choices, driving them towards potentially harmful alternatives, including the reliance on traditional herbal remedies and plants, which are themselves frequently implicated in the etiology of kidney damage in the region, creating a vicious cycle of disease and deprivation.

The etiological landscape of Chronic Kidney Disease (CKD) in our cohort is dominated by hypertension and diabetes, mirroring the broader epidemiological transition sweeping across Sub-Saharan Africa [15][16]. However, this trend is fueled by a confluence of local and structural factors, including the widespread use of nephrotoxic traditional medicines, rampant self-medication due to inadequate access to formal healthcare, and the adoption of diets rich in processed salts, sugars, and unhealthy fats. These dietary patterns, coupled with high rates of tobacco and alcohol use, create a perfect storm for the development of the very cardiovascular diseases that are the primary precursors to kidney failure. It is within this context of multimorbidity and socioeconomic hardship that the patient’s nutritional status precipitously declines. The relentless catabolic state induced by the dialysis procedure itself, compounded by uremia-induced anorexia, dietary restrictions, and inflammation, creates a perfect physiological storm for Protein-Energy Wasting (PEW). Our assessment, however, is constrained by significant methodological limitations that must be candidly acknowledged. The modest sample size (n = 17) and single-center design limit the generalizability of our findings. More critically, the absence of key biochemical parameters, most notably serum albumin and C-reactive protein (CRP), represents a fundamental gap in our analysis [7]. These biomarkers are indispensable for objectively diagnosing PEW, differentiating it from the effects of systemic inflammation, a common companion in dialysis patients, and for monitoring the efficacy of any nutritional interventions. Their omission in future studies would perpetuate a critical blind spot in our understanding of the pathophysiology at play.

Therefore, the findings of this study serve as an urgent call for a paradigm shift in the management of CKD in resource-limited settings like Chad. Moving beyond the mere provision of dialysis, we must champion a holistic, integrated care model that places systematic nutritional intervention at its core. This necessitates the immediate implementation of routine nutritional screening using validated tools like the MNA-SF, the development and deployment of culturally sensitive nutritional education programs that leverage locally available and affordable food sources, and the formal integration of dietitians into the multidisciplinary renal team to develop individualized meal plans. Ultimately, tackling the root causes of this crisis requires looking beyond the clinic walls to address the profound socioeconomic determinants of health. Policymakers must explore innovative models for broader financial support or food security programs targeted at this population. Without these comprehensive and simultaneous clinical, educational, and socioeconomic efforts to improve the quality of life, reduce mortality, and make dialysis a truly life-sustaining treatment for the chronically ill in Chad, the situation will remain critically hampered [7][8][14][15].