<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v3.0 20080202//EN" "http://dtd.nlm.nih.gov/publishing/3.0/journalpublishing3.dtd">
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="3.0" xml:lang="en" article-type="research article">
 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">
    crcm
   </journal-id>
   <journal-title-group>
    <journal-title>
     Case Reports in Clinical Medicine
    </journal-title>
   </journal-title-group>
   <issn pub-type="epub">
    2325-7075
   </issn>
   <issn publication-format="print">
    2325-7083
   </issn>
   <publisher>
    <publisher-name>
     Scientific Research Publishing
    </publisher-name>
   </publisher>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="doi">
    10.4236/crcm.2025.148054
   </article-id>
   <article-id pub-id-type="publisher-id">
    crcm-144682
   </article-id>
   <article-categories>
    <subj-group subj-group-type="heading">
     <subject>
      Articles
     </subject>
    </subj-group>
    <subj-group subj-group-type="Discipline-v2">
     <subject>
      Medicine 
     </subject>
     <subject>
       Healthcare
     </subject>
    </subj-group>
   </article-categories>
   <title-group>
    Digital Planning and Guided Surgery for Immediate Implants in Anterior Esthetic Area: Case Report
   </title-group>
   <contrib-group>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Alexandre
      </surname>
      <given-names>
       Montenegro
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff1"> 
      <sup>1</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Gonçalo Sobreira Pimentel
      </surname>
      <given-names>
       Neto
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff1"> 
      <sup>1</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Bruna
      </surname>
      <given-names>
       Ghiraldini
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff2"> 
      <sup>2</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Michel Aislan Dantas
      </surname>
      <given-names>
       Soares
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff2"> 
      <sup>2</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Lívia Ramalho
      </surname>
      <given-names>
       Crescencio
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff3"> 
      <sup>3</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Camila
      </surname>
      <given-names>
       Saggioro
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff3"> 
      <sup>3</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Aldir Nascimento
      </surname>
      <given-names>
       Machado
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff3"> 
      <sup>3</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Valquiria
      </surname>
      <given-names>
       Quinelato
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff3"> 
      <sup>3</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Priscila Ladeira
      </surname>
      <given-names>
       Casado
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff3"> 
      <sup>3</sup>
     </xref>
    </contrib>
   </contrib-group> 
   <aff id="aff1">
    <addr-line>
     aBrazilian Navy, Rio de Janeiro, Brazil
    </addr-line> 
   </aff> 
   <aff id="aff2">
    <addr-line>
     aIndependent Researcher, São Paulo, Brazil
    </addr-line> 
   </aff> 
   <aff id="aff3">
    <addr-line>
     aCenter for Education and Research in Implant Dentistry (CEPIM), Fluminense Federal University, Niterói, Brazil
    </addr-line> 
   </aff> 
   <pub-date pub-type="epub">
    <day>
     04
    </day> 
    <month>
     08
    </month>
    <year>
     2025
    </year>
   </pub-date> 
   <volume>
    14
   </volume> 
   <issue>
    08
   </issue>
   <fpage>
    422
   </fpage>
   <lpage>
    439
   </lpage>
   <history>
    <date date-type="received">
     <day>
      28,
     </day>
     <month>
      May
     </month>
     <year>
      2025
     </year>
    </date>
    <date date-type="published">
     <day>
      9,
     </day>
     <month>
      May
     </month>
     <year>
      2025
     </year> 
    </date> 
    <date date-type="accepted">
     <day>
      9,
     </day>
     <month>
      August
     </month>
     <year>
      2025
     </year> 
    </date>
   </history>
   <permissions>
    <copyright-statement>
     © Copyright 2014 by authors and Scientific Research Publishing Inc. 
    </copyright-statement>
    <copyright-year>
     2014
    </copyright-year>
    <license>
     <license-p>
      This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/
     </license-p>
    </license>
   </permissions>
   <abstract>
    <b>Background</b>: Despite the high rates of guided-surgery success in the aesthetic region, only a few studies describe both the planning protocol and the clinical-tomographic-surgical performance to reach short-term satisfactory outcomes. 
    <b>Aim</b>: The aim of the present study was to describe the planning applied to a guided surgery in the aesthetic region, and its clinical outcomes, by taking into consideration the periimplant tissue profile and the implant-supported prosthesis. 
    <b>Method</b>: This report describes the case of a female patient, at the age of 48 years, who presented herself seeking rehabilitation treatment based on osseointegrated implant and prosthesis, and to replenish the upper lateral incisor region which showed fracture under examination. 
    <b>Result</b>: The success of treatments based on implants in the aesthetic region depends on several factors, with emphasis on diagnostics and planning. The aforementioned stages are entangled in many benefits from guided surgery planning to conduction, such as surgery duration and acts’ reduction, lower discomfort, and iatrogenic injuries to soft and hard tissues. 
    <b>Conclusion</b>: The outcome in the rehabilitated aesthetic region was predictable, as well as functionally and aesthetically stable.
   </abstract>
   <kwd-group> 
    <kwd>
     Dental Implants
    </kwd> 
    <kwd>
      Bone regeneration
    </kwd> 
    <kwd>
      Computer-Guided Surgery
    </kwd> 
    <kwd>
      Aesthetic Region
    </kwd> 
    <kwd>
      Case Report
    </kwd>
   </kwd-group>
  </article-meta>
 </front>
 <body>
  <sec id="s1">
   <title>1. Introduction</title>
   <p>Mouth rehabilitation has been following technological innovations aimed at improving and decision-making in dental procedures. Panoramic X-ray has limitations in implants’ surgical planning; moreover, freehand surgery also has limitations that lead to different outcomes due to professional skills and decisions made during surgery, without real previous planning <xref ref-type="bibr" rid="scirp.144682-1">
     [1]
    </xref>. Cone-beam computed tomography is recommended to start the surgical planning applied to osseointegratade implants. Since 2002, implant dentistry has assessed and innovated with special software for guided surgeries and prosthesis installation on implants. Guided surgeries are recommended for a whole range of implant rehabilitation cases, including partial or total edentulous, as well as aesthetical nature areas <xref ref-type="bibr" rid="scirp.144682-2">
     [2]
    </xref>. These concepts have led to changes in surgical perspectives given the possibility to plan implant installations along with temporary or permanent prostheses. Computed tomography and the development of new software enable almost realistic-like virtual planning aimed at accurately guiding to a specific target in rehabilitating plans <xref ref-type="bibr" rid="scirp.144682-3">
     [3]
    </xref>.</p>
   <p>Accurate pre-operative planning applied to aesthetic regions, either for implant installation or for the manufacture of prosthetic restorations, as well as for gingival contour predictability, is a fundamental requirement for a successful rehabilitation, based on osseointegratade implants <xref ref-type="bibr" rid="scirp.144682-4">
     [4]
    </xref>. Cone-beam computed tomography, intraoral scanning and the availability of 3D printers made the practice of virtually planning implants and of using a surgical guide to point out the accurate and correct locations for milling and implant installation accessible, and it leads to aesthetic and biomechanical predictability <xref ref-type="bibr" rid="scirp.144682-5">
     [5]
    </xref>.</p>
   <p>The virtual planning of surgery in aesthetic regions became an excellent tool for treatments based on osseointegratade implants, because periimplant tissue stability, absorption of loads along the long axis, easy cleaning and satisfactory outcomes are the elements accounting for proper tridimensional implant positioning <xref ref-type="bibr" rid="scirp.144682-6">
     [6]
    </xref>-<xref ref-type="bibr" rid="scirp.144682-8">
     [8]
    </xref>. Aspects, such as the ideal distance between implants, between implants and dental elements, and implant depth, can also be controlled through this technique. There is a close association between a high success rate and shorter surgery duration due to previous virtual surgical planning <xref ref-type="bibr" rid="scirp.144682-9">
     [9]
    </xref>.</p>
   <p>The development and widespread use of different software for planning and prosthetic design allowed combining waxing purposes, which can now be virtually performed based on surgical planning <xref ref-type="bibr" rid="scirp.144682-6">
     [6]
    </xref>-<xref ref-type="bibr" rid="scirp.144682-8">
     [8]
    </xref>. These software types are diagnostic tools to previously analyze implant installation areas and to propose different alternatives to each case, a fact that helps reduce iatrogenic cases <xref ref-type="bibr" rid="scirp.144682-10">
     [10]
    </xref> <xref ref-type="bibr" rid="scirp.144682-11">
     [11]
    </xref>.</p>
   <p>Nowadays, guides’ manufacturing is based on CT image overlay (DICOM) of data resulting from digital images of dental arches by using standard tessellation language (STL) intraoral scanning. Stereolithographic guides are made through Computer-Aided Design /Computer-Aided Manufacturing (CAD/CAM) by printing or milling devices <xref ref-type="bibr" rid="scirp.144682-6">
     [6]
    </xref>-<xref ref-type="bibr" rid="scirp.144682-8">
     [8]
    </xref>.</p>
   <p>Digital techniques are not only crucial for precision in implant placement but also represent a significant leap in enhancing overall patient care and outcomes in dentistry. According to recent findings, these methods facilitate minimally invasive procedures, reduce recovery time, and improve the predictability of aesthetic and functional results, thereby transforming traditional approaches to mouth rehabilitation <xref ref-type="bibr" rid="scirp.144682-3">
     [3]
    </xref>. Understanding these benefits within the wider medical field highlights the importance of these innovations in advancing patient-centered care.</p>
   <p>Despite the high rates of guided-surgery success in the aesthetic region, only a few studies describe both the planning protocol and the clinical-tomographic-surgical performance to reach short-term satisfactory outcomes. The aim of the present study was to describe the planning applied to a guided surgery in the aesthetic region, and its clinical outcomes, by taking into consideration the periimplant tissue profile and the implant-supported prosthesis.</p>
  </sec><sec id="s2">
   <title>2. Clinical Case Report</title>
   <p>Female patient, herein identified as FFF, at the age of 48 years, presented herself to the dentistry clinic of the Brazilian Navy seeking rehabilitation treatment based on osseointegratade implant and prosthesis, and to replenish the upper lateral incisor region (<xref ref-type="fig" rid="fig1">
     Figure 1
    </xref> and <xref ref-type="fig" rid="fig2">
     Figure 2
    </xref>). Under radiographic examination it was evident the presence of tooth fracture. The patient presented full dentition in the lower dental arch with the absence of the maxillary lateral incisor crown. The medical and familiar history showed no systemic disease, no medication use or any genetic disease. Patient had no history of previous intervention. In addition to the clinical and radiographic examinations, blood tests, such as complete blood count, coagulogram and glycated hemoglobin, were requested to confirm no systemic contraindication to the surgical procedure.</p>
   <fig id="fig1" position="float">
    <label>Figure 1</label>
    <caption>
     <title>Figure 1. Initial aspect showing root fracture of superior lateral incisor with gingival tissue invasion and aesthetic contour loss.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2771931-rId15.jpeg?20250811111129" />
   </fig>
   <fig id="fig2" position="float">
    <label>Figure 2</label>
    <caption>
     <title>Figure 2. Initial aspect clinically showing root fracture of superior lateral incisor, gingival tissue invasion and aesthetic contour loss (occlusal view).</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2771931-rId16.jpeg?20250811111129" />
   </fig>
   <p>Guided surgery was the therapy of choice to operate on the upper dental arch due to recommendation for tridimensional implant accuracy in this region. It was done to favor aesthetic aspects and bone availability to implant performance based on the remaining root of the superior lateral incisor, as a spatial reference for guided surgical planning (<xref ref-type="fig" rid="fig3">
     Figure 3
    </xref>).</p>
   <fig id="fig3" position="float">
    <label>Figure 3</label>
    <caption>
     <title>Figure 3. Tomographic aspect showing bone availability at dental element 12 region: 16 mm in height and 5 mm in thickness.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2771931-rId17.jpeg?20250811111129" />
   </fig>
   <sec id="s2_1">
    <title>2.1. Guided Planning</title>
    <p>Surgical planning was sent to the laboratory in video format along with DICOM images and their printed pictures (<xref ref-type="fig" rid="fig3">
      Figure 3
     </xref>). Epikut (by S.I.N., São Paulo, Brasil) was the guided surgery system of choice and Cone Morse (CM) 3.5 × 13 mm (reference ILCM3513) was the selected implant type. Virtual planning was carried out in Exoplan software (Smart Dent-Germany), which was used to manufacture the surgical guide based on imported STL files resulting from digital scanning (Cerec AC Omnicam 4.6, Dentisply Sirona, SP, Brazil) by using H6.5 washers (<xref ref-type="fig" rid="fig4">
      Figure 4
     </xref> and <xref ref-type="fig" rid="fig5">
      Figure 5
     </xref>). The guide was printed in Anycubic Photon S device and Smartdent Clear resin (Smart Dent-Germany) was the base material of choice.</p>
    <fig id="fig4" position="float">
     <label>Figure 4</label>
     <caption>
      <title>Figure 4. Surgical guide planned in Exoplan software (Smart Dent-Germany) and manufactured with STL exports.</title>
     </caption>
     <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2771931-rId18.jpeg?20250811111130" />
    </fig>
    <fig id="fig5" position="float">
     <label>Figure 5</label>
     <caption>
      <title>Figure 5. Surgical guide manufactured in Smartdent clear resin (Smart Dent-Germany), in 3D type Anycubic Photon S printer.</title>
     </caption>
     <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2771931-rId19.jpeg?20250811111130" />
    </fig>
   </sec>
   <sec id="s2_2">
    <title>2.2. Minimally Traumatic Tooth Extraction</title>
    <p>Initially, based on diagnostic examinations, the patient was subjected to local anesthesia for anterior superior alveolar plexus block because the prognostic for immediate installation of post-extraction implant was classified as good. This procedure was performed with 4% Articaine added with epinephrine (at ratio of 1:100,000). Minimally traumatic tooth extraction was carried out starting from periotomy of the palatal, distal and mesial surfaces to make the extraction of the dental element easier and to make this procedure the least traumatic possible, as well as to preserve the vestibular bone plate and to support the soft tissue around element 12 (<xref ref-type="fig" rid="fig6">
      Figure 6
     </xref>).</p>
    <fig id="fig6" position="float">
     <label>Figure 6</label>
     <caption>
      <title>Figure 6. Clinical aspect right after tooth extraction showing the favorable mucosa contour and papillae and bone plates preservation.</title>
     </caption>
     <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2771931-rId20.jpeg?20250811111130" />
    </fig>
    <p>The surgical guide received the windows to assess their stabilization, because it provides greater procedural safety. It is projected in areas presenting good-quality and sufficient bone tissue selected during digital planning (<xref ref-type="fig" rid="fig7">
      Figure 7
     </xref>).</p>
    <fig id="fig7" position="float">
     <label>Figure 7</label>
     <caption>
      <title>Figure 7. Positioned surgical guide.</title>
     </caption>
     <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2771931-rId21.jpeg?20250811111130" />
    </fig>
    <p>The implant was installed based on following the sequence of Epikut Guided Surgery System Surgical Kit Drills by SIN Implants (BKCSEG 0201, S.I.N., São Paulo, Brazil), according to manufacturer’s recommendations.</p>
    <p>Implant positioning followed the tridimensional positioning principles by keeping the minimum distance of 12 mm from implant platform and from adjacent teeth, and 3 - 4 mm distance between gingival margin and implant platform. The installed implant recorded 45N torque (<xref ref-type="fig" rid="fig8">
      Figure 8
     </xref> and <xref ref-type="fig" rid="fig9">
      Figure 9
     </xref>).</p>
    <fig id="fig8" position="float">
     <label>Figure 8</label>
     <caption>
      <title>Figure 8. Installation of CM Epikut 3.5 × 13 mm type implant (S.I.N., São Paulo, Brazil).</title>
     </caption>
     <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2771931-rId22.jpeg?20250811111130" />
    </fig>
    <fig id="fig9" position="float">
     <label>Figure 9</label>
     <caption>
      <title>Figure 9. Placement of CM Epikut 3.5 × 13 mm type implant (occlusal view).</title>
     </caption>
     <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2771931-rId23.jpeg?20250811111130" />
    </fig>
    <p>The surgical guide was removed and bone replenishing was carried out with biomaterial in the space between the installed implant and the vestibular bone plate, after implant installation. Replenishing was performed through Alobone® allograft (Osseocon, Rio de Janeiro, RJ, Brazil) (<xref ref-type="fig" rid="fig10">
      Figure 10
     </xref>). Chlorhexidine 0.12% was indicated twice daily for 14 days postoperatively.</p>
    <fig id="fig10" position="float">
     <label>Figure 10</label>
     <caption>
      <title>Figure 10. Immediate clinical aspect showing the favorable position of the installed implant and the integrity of the remaining soft vestibular tissues (occlusal view).</title>
     </caption>
     <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2771931-rId24.jpeg?20250811111130" />
    </fig>
    <p>The choice of the Epikut system may be attributed to its high clinical success rate in implant dentistry, which underscores its reliability and effectiveness. Similarly, Exoplan software is favored for its specificity and ease of use, which facilitates precise planning and execution, enhancing the overall efficiency of the procedure.</p>
   </sec>
   <sec id="s2_3">
    <title>2.3. Provisional Tooth Creation</title>
    <p>The provisional tooth was created in B1 resin and made up by El Lab Externo, with emergency profile captured in A1 flow resin, based on using the connection in titanium provisional cylinder (CPTMU 3502-H, S.I.N., São Paulo Brazil), right after implant installation (<xref ref-type="fig" rid="fig11">
      Figure 11
     </xref> and <xref ref-type="fig" rid="fig12">
      Figure 12
     </xref>).</p>
    <fig id="fig11" position="float">
     <label>Figure 11</label>
     <caption>
      <title>Figure 11. Immediate provisional tooth over the CM Epikut 3.5 × 13 mm implant printed in B1 resin and made up by El Lab Externo.</title>
     </caption>
     <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2771931-rId25.jpeg?20250811111131" />
    </fig>
    <fig id="fig12" position="float">
     <label>Figure 12</label>
     <caption>
      <title>Figure 12. Immediate provisional tooth over the CM Epikut 3.5 × 13 mm made up by El Lab Externo with emergency profile captured in A1 flow resin, based on using titanium provisional cylinder connection (occlusal view).</title>
     </caption>
     <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2771931-rId26.jpeg?20250811111131" />
    </fig>
    <p>The concavity in the sub-gingival portion of the prosthetic pillar was stressed with the aid of diamond drills under refrigeration. It was done to get thicker periimplant tissue, which accounts for long-term stability in gingival margin positioning. It was possible observing immediate aesthetics outcomes due to the use of provisional tooth, based on the virtual planning and on rehabilitating procedure accuracy (<xref ref-type="fig" rid="fig13">
      Figure 13
     </xref>).</p>
    <fig id="fig13" position="float">
     <label>Figure 13</label>
     <caption>
      <title>Figure 13. Initial aspect showing the root remains of dental element 12 (A). Immediate provisional tooth over CM Epikut 3.5 × 13 mm implant (SIN, São Paulo, Brazil), printed in B1 resin and made up by El Lab Externo, with emergency profile captured in A1 flow resin, by using titanium provisional cylinder connection (B).</title>
     </caption>
     <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2771931-rId27.jpeg?20250811111130" />
    </fig>
    <p>Provisional restoration can be cemented and the hole to access the pin can be closed after 20N torque is applied to the prosthetic pillar. The patient appeared extremely happy with the immediate clinical aspect.</p>
    <p>Six months later, the definitive porcelain prosthesis EUCLA type abutment (EUCLAMU 3502-H, S.I.N., São Paulo, Brazil) was placed (<xref ref-type="fig" rid="fig14">
      Figure 14
     </xref>). One year after prostheses placement patients showed aesthetic satisfactory result, according to herself report and clinical evaluation.</p>
    <p>It’s important to affirm that the patient was satisfied with the clinical result. In addition, the patient agreed with the proposed method from the beginning of the treatment, showing a positive reaction to the results achieved. No adverse events were observed.</p>
    <fig id="fig14" position="float">
     <label>Figure 14</label>
     <caption>
      <title>Figure 14. Final clinical aspect with the definitive porcelain prosthesis in frontal (A) and occlusal view (B). Note the aesthetics, the periimplant mucosa contour. This case was carried out based on virtual guided surgery planning.</title>
     </caption>
     <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2771931-rId28.jpeg?20250811111130" />
    </fig>
   </sec>
  </sec><sec id="s3">
   <title>3. Discussion</title>
   <p>Implant dentistry has been having great impact on how we deal with edentulism. Rehabilitation based on dental implant has become the standard procedure to replace the lost teeth. Some parameters must be observed in aesthetic rehabilitation in order to reach long-term success. Gingiva biotype, smile line, dental elements’ color, periimplant mucosa contour, papillae preservation, and the thickness and height of the underlying bone ridge, are among the main aspects observed in the maxilla anterior region <xref ref-type="bibr" rid="scirp.144682-12">
     [12]
    </xref>-<xref ref-type="bibr" rid="scirp.144682-14">
     [14]
    </xref>. The aim of all these factors does not only lie on reaching the expected aesthetics, but also on having treatment predictability when it comes to dental implants. The present case report opens room for discussions about some relevant points from the surgical and prosthesis aspect viewpoint, as well as about the emergence of digital planning as excellent tool to implant dentistry. Outcomes have clearly pointed out the functionality and aesthetics acquisition within a short period-of-time due to guided surgery employment.</p>
   <p>Scientific evidence shows that early digital planning and 3D guided surgery duration were marked by concepts established in 2005, which have outspread guided surgery employment. The technology of choice at digital planning scope is called CAD (Computer Aided Design), which is an integration system substantiated by computer sciences. Digital planning is carried out in DTX software, which can import files in STL format. These files result from intra-oral scanning or from tomographic images. This tool allows previously planning surgery conduction by determining the ideal location for implant installation based on bone amount and quality. It also allows visualizing important accidents and anatomic structures that are often identified in other analogous tools, as well as takes into account the prosthetic needs at high positioning accuracy, reproducibility, color and shape <xref ref-type="bibr" rid="scirp.144682-15">
     [15]
    </xref>.</p>
   <p>The guided planning uses tomographic images associated with up-to-date 3D software capable of accurately and faithfully reproducing the anatomic structures of periimplants, as well as of their intermediate prosthetics and prosthesis, before the surgical procedure. It makes the production of surgical guides in high-accuracy acrylic resin feasible. These guides orient the implant insertion axis and optimize surgery duration, besides benefitting trans-surgical and post-surgical time <xref ref-type="bibr" rid="scirp.144682-16">
     [16]
    </xref>-<xref ref-type="bibr" rid="scirp.144682-20">
     [20]
    </xref>.</p>
   <p>Al Yafi F. et al. (2019) stated that the guided implant surgery is more accurate and reliable than freehanded implant surgeries. It is so, because the digital workflow for guided surgery follows a protocol to generate a tridimensional digital plan to be transferred to the patients’ mouth through the surgical guide and protocol in order to reduce deviation and error risks <xref ref-type="bibr" rid="scirp.144682-21">
     [21]
    </xref>. All herein reported case stages, from tomography performance to tomography coupling to STL scanning, led to surgical accuracy and to high post-operative success predictability.</p>
   <p>The guided surgery represents a less invasive, conservative and more accurate surgical modality <xref ref-type="bibr" rid="scirp.144682-22">
     [22]
    </xref>. According to Balem et al. (2010), the guided surgery and prototyping represent a new wave in dentistry, according to which, procedures become safer, predictable and less complex <xref ref-type="bibr" rid="scirp.144682-23">
     [23]
    </xref>. In addition, the adopted surgical kits and the implant of choice, based on manufacturers’ recommendations, are essential for implants’ primary stability and for trans-surgical handling. It is also important highlighting that surgical guide manufacture must follow the manufacturer’s requirements, because they lead to accurate surgical conduction based on selected implant size.</p>
   <p>The choice made for guided surgeries enables performing implant installations based on flap reflection, or not. The case presented by each patient is what differentiates the choice for a given surgical access, and one must take into account the need of bone and/or conjunctive graft followed by implant installation, a fact that demands opening the flap. Whenever there is no need of graft, one can choose the closed surgery, because it is possible building a tomographic guide after the tomography to virtually plan the best implant anchorage area <xref ref-type="bibr" rid="scirp.144682-24">
     [24]
    </xref>. The best positioning predictability is observed when the virtual planning is carried out by accurately respecting the 2mm distance between the implant and the vestibular bone plate, and the 3 - 4 mm distance between the gingival margin and the implant platform. It must be done to reach the best tridimensional implant control and, consequently, to allow adjacent tissue recovery <xref ref-type="bibr" rid="scirp.144682-25">
     [25]
    </xref>-<xref ref-type="bibr" rid="scirp.144682-27">
     [27]
    </xref>. This fact is clearly identified during immediate post-operative outcomes and it is mediated by guided rehabilitation, as shown in the current report.</p>
   <p>Studies have evidenced that a surgical approach without flap can have additional advantages when it comes to traditional protocols with mucoperiosteal flap that, in its turn, can be related to higher reabsorption rates for the alveolar bone crest and of bone-implant contact (IOC) loss in implant’s cervical region <xref ref-type="bibr" rid="scirp.144682-28">
     [28]
    </xref>. According to studies of remarkable scientific relevance, one can expect approximately 1mm of vestibular gingival retraction 1 year after implant installation <xref ref-type="bibr" rid="scirp.144682-29">
     [29]
    </xref>. We believe that adjacent tissues in the present report were preserved due to the adoption of the guided surgery without flap, no periimplant gingival retraction was identified.</p>
   <p>Guided surgery predictability is only possible in specific software available in the market that generate linear and angle coordinates for washers’ positioning. All tomographic images were generated in DICOM format and converted by the adopted software into the proper format required by each one of them <xref ref-type="bibr" rid="scirp.144682-30">
     [30]
    </xref>. Other studies have pointed out the advantages of the guided surgery, such as safe, simple, reliable and accurate technique; positive receptivity by patients; shorter surgical time; minimum post-operative discount; faster prosthesis installation <xref ref-type="bibr" rid="scirp.144682-31">
     [31]
    </xref>. Reverse planning stands out in the literature, and it is substantiated by several studies that state the proper use of this resource, which significantly reduces fail rates at the initial rehabilitation stage <xref ref-type="bibr" rid="scirp.144682-32">
     [32]
    </xref>. Reserve planning was an excellent resource for satisfactory clinical outcomes in this study. The 3D diagnostics and digital planning allowed determining the ideal location for dental implant installation with the aid of a guide, since it reduced the chances of having significant anatomic accidents.</p>
   <p>This technique presents some limitations, such as higher costs due to the need of having a customized surgical guide and the necessary minimum amount of bones <xref ref-type="bibr" rid="scirp.144682-6">
     [6]
    </xref>-<xref ref-type="bibr" rid="scirp.144682-8">
     [8]
    </xref>. The main variation in comparison to the conventional technique is linked to milling sizes, which present longer upper length in the guided surgery system. Patient’s mouth opening in the implant region must match the use of millings and installation keys of the system of choice. Limited mouth opening can interfere with implant instruments and installation, and cause surgery interruption.</p>
   <p>As for the moment to extract the dental element and to install the dental implant, it is possible taking into consideration some facts evidenced in scientific studies according to which, one can expect horizontal loss close to 30% of the bone volume three months after tooth extraction <xref ref-type="bibr" rid="scirp.144682-33">
     [33]
    </xref>. Accordingly, immediate implant installation associated with bone graft avoids the need of further regeneration procedures and emerges as excellent option for patients recommended for this technique <xref ref-type="bibr" rid="scirp.144682-34">
     [34]
    </xref>. Besides, the use of surgical techniques that avoid incision acts, as well as gingival papillae displacement, is associated with lower bone loss standards <xref ref-type="bibr" rid="scirp.144682-35">
     [35]
    </xref>. We herein opted for preserving the adjacent tissues.</p>
   <p>With respect to the immediate prosthetic and rehabilitating scope, it is important highlighting the need of installing the prosthetic pillar at the time to install the implant. It is known that the repetition of prosthetic pillar’s connections and disconnections leads to marginal recession and to bone absorption in animal models <xref ref-type="bibr" rid="scirp.144682-36">
     [36]
    </xref>. Disruption of the junctional epithelium of the periimplant biological space was removed and the installation of new pillars can lead to new apical biological space at implant level, with consequent bone resorption. Humans show traces that more than two connections affect the periimplant mucosa sealing. Screwed provisional restoration installation at surgery time can be a quite feasible alternative; it must be disconnected three months later for the modeling stage and for the installation of the pillar associated with the definitive restoration <xref ref-type="bibr" rid="scirp.144682-34">
     [34]
    </xref>. As for the current case report, definitive prosthesis manufacture happened 6 months after implant installation, and it showed full periimplant mucosa stabilization and satisfactory aesthetic profile.</p>
   <p>Based on relevant scientific studies, when the problem is the vestibular gingival retraction, one can expect approximately 1mm retraction 1 year after implant installation. The use of customized prosthetic pillars minimizes such a loss, since it keeps soft tissue architecture <xref ref-type="bibr" rid="scirp.144682-37">
     [37]
    </xref>-<xref ref-type="bibr" rid="scirp.144682-39">
     [39]
    </xref>. Data in scientific studies show either vertical increase or lack of tissue recession at the casuistic margin higher than 80% after 2-year follow-up. It sets the biological space in the prosthetic pillar structure and, consequently, preserves the bone crest of the periimplant region <xref ref-type="bibr" rid="scirp.144682-36">
     [36]
    </xref> <xref ref-type="bibr" rid="scirp.144682-38">
     [38]
    </xref>.</p>
   <p>Levine et al. (2017) considered 10 stages to reach a successful surgery to install immediate implants in the aesthetic region, namely: two planning stages, five surgical stages and three prosthetic stages. Altogether, these stages aim at minimizing soft and hard tissue complications to achieve the ideal implant aesthetic restoration <xref ref-type="bibr" rid="scirp.144682-40">
     [40]
    </xref>. We can consider that the herein introduced clinical case followed these ten stages, because we have employed two planning stages (tomographic and reverse planning), five surgical stages (non-traumatic tooth extraction, tissue manipulation, biomaterial installation, guided surgery and proper implant positioning) and thee prosthetic stages (manufacture of the milled provisional material, porcelain prosthesis design and digital prosthesis planning).</p>
   <p>With respect to treatment based on dental implants in the aesthetic region, the multi-factorial dependence on clinical success is known, with emphasis on diagnostics and planning. These stages influence the reduction in intervention numbers, and it also reduces the risk of sequelae in soft and hard tissue structures, without affecting rehabilitation functional and aesthetic profiles. The guided surgery is an excellent alternative when the amount of bone in the patient is enough to receive dental implants without the need for a long surgical cut <xref ref-type="bibr" rid="scirp.144682-41">
     [41]
    </xref>. This technique leads to surgical predictability, which enables much more safety for surgeons and comfort to patients <xref ref-type="bibr" rid="scirp.144682-42">
     [42]
    </xref>-<xref ref-type="bibr" rid="scirp.144682-45">
     [45]
    </xref>. The present case report allows observing that the guided surgery was an excellent alternative, because the patient’s clinical response was extremely satisfactory, and it allowed making an aesthetically ideal porcelain prosthesis in the shortest period-of-time.</p>
   <p>However, it’s essential to emphasize that while the current case report underscores the successful use of guided surgery, patient-specific factors must be considered as they can influence outcomes. For instance, differences in bone density can greatly affect implant stability and osseointegration. Furthermore, the patient’s overall health, including immune response and healing capacity, plays a critical role in recovery time and success rates. In this particular case, the absence of systemic health issues facilitated a straightforward procedure. Future studies should focus on how personalized assessments and adaptations can enhance results, ensuring the full benefits of guided surgery are achieved for each individual patient.</p>
   <p>While guided surgery techniques offer precision and predictability, they are not without complications or limitations. Potential issues include inaccuracies in the placement of surgical guides caused by deviations during imaging, guide fabrication, or placement errors during surgery. Additionally, the reliance on digital planning and technology requires significant training and familiarity, which can be a barrier for some practitioners <xref ref-type="bibr" rid="scirp.144682-46">
     [46]
    </xref>. Costs associated with the technology and the potential for increased surgical time due to guide placement are also considerations. Despite these challenges, advancements in technology continue to mitigate many limitations, improving outcomes progressively.</p>
   <p>Virtual diagnostic and planning based on current scientific evidence, careful procedural planning and using high-quality materials are the essential requirements for a successful procedure. Guided surgery can accurately transfer virtual planning to the surgical act; besides, it is one more tool that helps dental surgeons in the dental implant field reach the best outcomes. As for the herein introduced clinical case, we have combined the following factors: (a) proper dental implant planning; (b) accurate soft tissue handling; (c) effective choice for the biomaterial; and (d) using new technologies associated with planning, and surgical and prosthetic performance. Based on these guidelines, it was possible ensuring a predictable aesthetic and functional outcome.</p>
  </sec><sec id="s4">
   <title>4. Conclusion</title>
   <p>The success of treatments based on implants in the aesthetic region depends on several factors, with emphasis on diagnostics and planning. The aforementioned stages are entangled in many benefits from guided surgery planning to conduction, such as surgery duration and acts’ reduction, lower discomfort, and iatrogenic injuries to soft and hard tissues. The outcome in the rehabilitated aesthetic region was predictable, as well as functionally and aesthetically stable.</p>
  </sec><sec id="s5">
   <title>Patients Perspective</title>
   <p>From the patient’s point of view, tooth fracture already indicated disability, and the patient was willing to perform the surgical procedure, with guided surgery, as discussed with the team. The patient was satisfied with the immediate and long-term aesthetic and functional results, with no complications to report.</p>
  </sec><sec id="s6">
   <title>Patient Consent</title>
   <p>Written informed consent was obtained from the patient for publication of this case report and any accompanying images including clinical pictures and investigations. A copy of the written consent and approval by ethics committee from our institution are available for review by the Editor of this journal.</p>
  </sec><sec id="s7">
   <title>Funding</title>
   <p>The authors declare that no funds, grants, or other support were received during the preparation of this manuscript.</p>
  </sec>
 </body><back>
  <ref-list>
   <title>References</title>
   <ref id="scirp.144682-ref1">
    <label>1</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Chen, P. and Nikoyan, L. (2021) Guided Implant Surgery: A Technique Whose Time Has Come. Dental Clinics of North America, 65, 67-80. &gt;https://doi.org/10.1016/j.cden.2020.09.005
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref2">
    <label>2</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Neto, M.D.E.H., Magalhães, A.C.P., Carneiro, T.A.P.N., André, N.V. and Andrade, G.C. (2012) Planejamento virtual e cirurgia guiada na reabilitação de maxila edêntula. Jornal ILAPEO, 6, 180-188.
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref3">
    <label>3</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Salviano, S.H., Lopes, J.C.A., da Silva Brum, I., Machado, K., Pedrazzi, M.T. and de Carvalho, J.J. (2023) Digital Planning for Immediate Implants in Anterior Esthetic Area: Immediate Result and Follow-Up after 3 Years of Clinical Outcome—Case Report. Dentistry Journal, 11, Article No. 15. &gt;https://doi.org/10.3390/dj11010015
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref4">
    <label>4</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     De Vico, G., Spinelli, D., Bonino, M., Schiavetti, R., Pozzi, A. and Ottria, L. (2012) Computer-Assisted Virtual Treatment Planning Combined with Flapless Surgery and Immediate Loading in the Rehabilitation of Partial Edentulies. Oral Implantology (Rome), 5, 3-10.
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref5">
    <label>5</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Elsayed, A., Farrag, G., Chaar, M., Abdelnabi, N. and Kern, M. (2018) Influence of Different CAD/CAM Crown Materials on the Fracture of Custom-Made Titanium and Zirconia Implant Abutments after Artificial Aging. The International Journal of Prosthodontics, 32, 91-96. &gt;https://doi.org/10.11607/ijp.6137
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref6">
    <label>6</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Buser, D., Sennerby, L. and De Bruyn, H. (2016) Modern Implant Dentistry Based on Osseointegration: 50 Years of Progress, Current Trends and Open Questions. Periodontology 2000, 73, 7-21. &gt;https://doi.org/10.1111/prd.12185
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref7">
    <label>7</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Katsoulis, J., Pazera, P. and Mericske-Stern, R. (2009) Prosthetically Driven, Computer-Guided Implant Planning for the Edentulous Maxilla: A Model Study. Clinical Implant Dentistry and Related Research, 11, 238-245. &gt;https://doi.org/10.1111/j.1708-8208.2008.00110.x
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref8">
    <label>8</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Jang, J.Y., Lee, S.J. and Lee, J.D. (2020) Considerations in the Replacement of Over-retained Primary Teeth with Implant Restorations in the Esthetic Zone: A Case Report. Journal of Esthetic and Restorative Dentistry, 32, 272-279. &gt;https://doi.org/10.1111/jerd.12569
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref9">
    <label>9</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Nuss, K.C.B., Gomes, F.V., Mattis, F. and Mayer, L. (2016) Grau de confiabilidade na reprodução do planejamento virtual para o posicionamento final de implantes por meio de cirurgia guiada: relato de caso. Revista da Faculdade de Odontologia-UPF, 21, 102-108. &gt;https://doi.org/10.5335/rfo.v21i1.5245
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref10">
    <label>10</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Chackartchi, T., Romanos, G.E., Parkanyi, L., Schwarz, F. and Sculean, A. (2022) Reducing Errors in Guided Implant Surgery to Optimize Treatment Outcomes. Periodontology 2000, 88, 64-72. &gt;https://doi.org/10.1111/prd.12411
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref11">
    <label>11</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Colombo, M., Mangano, C., Mijiritsky, E., Krebs, M., Hauschild, U. and Fortin, T. (2017) Clinical Applications and Effectiveness of Guided Implant Surgery: A Critical Review Based on Randomized Controlled Trials. BMC Oral Health, 17, Article No. 150. &gt;https://doi.org/10.1186/s12903-017-0441-y
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref12">
    <label>12</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Chiapasco, M. and Casentini, P. (2018) Horizontal Bone-Augmentation Procedures in Implant Dentistry: Prosthetically Guided Regeneration. Periodontology 2000, 77, 213-240. &gt;https://doi.org/10.1111/prd.12219
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref13">
    <label>13</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Wennerberg, A. and Albrektsson, T. (2010) Current Challenges in Successful Rehabilitation with Oral Implants. Journal of Oral Rehabilitation, 38, 286-294. &gt;https://doi.org/10.1111/j.1365-2842.2010.02170.x
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref14">
    <label>14</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Çehreli, M., Şahin, S. and Akça, K. (2004) Role of Mechanical Environment and Implant Design on Bone Tissue Differentiation: Current Knowledge and Future Contexts. Journal of Dentistry, 32, 123-132. &gt;https://doi.org/10.1016/j.jdent.2003.09.003
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref15">
    <label>15</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Ganz, S.D. (2015) Three-Dimensional Imaging and Guided Surgery for Dental Implants. Dental Clinics of North America, 59, 265-290. &gt;https://doi.org/10.1016/j.cden.2014.11.001
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref16">
    <label>16</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Alauddin, M.S., Baharuddin, A.S. and Mohd Ghazali, M.I. (2021) The Modern and Digital Transformation of Oral Health Care: A Mini Review. Healthcare, 9, Article No. 118. &gt;https://doi.org/10.3390/healthcare9020118
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref17">
    <label>17</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Schwendicke, F., Samek, W. and Krois, J. (2020) Artificial Intelligence in Dentistry: Chances and Challenges. Journal of Dental Research, 99, 769-774. &gt;https://doi.org/10.1177/0022034520915714
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref18">
    <label>18</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Hoarau, R., Zweifel, D., Simon, C. and Broome, M. (2014) The Use of 3D Planning in Facial Surgery: Preliminary Observations. Revue de Stomatologie, de Chirurgie Maxillo-Faciale et de Chirurgie Orale, 115, 353-360. &gt;https://doi.org/10.1016/j.revsto.2014.07.006
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref19">
    <label>19</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Weijs, W.L.J., Coppen, C., Schreurs, R., Vreeken, R.D., Verhulst, A.C., Merkx, M.A.W., et al. (2016) Accuracy of Virtually 3D Planned Resection Templates in Mandibular Reconstruction. Journal of Cranio-Maxillofacial Surgery, 44, 1828-1832. &gt;https://doi.org/10.1016/j.jcms.2016.08.024
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref20">
    <label>20</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Witjes, M.J.H., Schepers, R.H. and Kraeima, J. (2018) Impact of 3D Virtual Planning on Reconstruction of Mandibular and Maxillary Surgical Defects in Head and Neck Oncology. Current Opinion in Otolaryngology&amp;Head&amp;Neck Surgery, 26, 108-114. &gt;https://doi.org/10.1097/moo.0000000000000437
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref21">
    <label>21</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Al Yafi, F., Camenisch, B. and Al-Sabbagh, M. (2019) Is Digital Guided Implant Surgery Accurate and Reliable? Dental Clinics of North America, 63, 381-397. &gt;https://doi.org/10.1016/j.cden.2019.02.006
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref22">
    <label>22</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Pegorini, V.S., et al. (2013) Virtual Planning and Surgery in Guided Implantology. Revista Saúde Integrada, 6, 243-261.
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref23">
    <label>23</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Barbosa Alencar, P.N., Roque-Torres, G.D., Meneses-López, A., Frab Norberto Bóscolo, F.N.B., De Almeida, S.M. and Groppo, F.C. (2015) Utilización del prototipado rápido en la odontología. Revista Estomatológica Herediana, 25, 167-174. &gt;https://doi.org/10.20453/reh.v25i2.2463
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref24">
    <label>24</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Vercruyssen, M., Fortin, T., Widmann, G., Jacobs, R. and Quirynen, M. (2014) Different Techniques of Static/Dynamic Guided Implant Surgery: Modalities and Indications. Periodontology 2000, 66, 214-227. &gt;https://doi.org/10.1111/prd.12056
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref25">
    <label>25</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Grunder, U., Gracis, S. and Capelli, M. (2005) Influence of the 3-D Bone-to-Implant Relationship on Esthetics. International Journal of Periodontics&amp;Restorative Dentistry, 25, 113-119.
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref26">
    <label>26</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Paolantonio, M., Dolci, M., Scarano, A., D’Archivio, D., Di Placido, G., Tumini, V., et al. (2001) Immediate Implantation in Fresh Extraction Sockets. a Controlled Clinical and Histological Study in Man. Journal of Periodontology, 72, 1560-1571. &gt;https://doi.org/10.1902/jop.2001.72.11.1560
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref27">
    <label>27</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Saadoun, A.P., Le Gall, M.G. and Touati, B. (2004) Current Trends in Implantology: Part II—Treatment Planning, Aesthetic Considerations, and Tissue Regeneration. Practical Procedures in Aesthetic Dentistry, 16, 707-714.
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref28">
    <label>28</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Frizzera, F., Calazans, N., Pascoal, C., Martins, M. and Mendonça, G. (2021) Flapless Guided Implant Surgeries Compared with Conventional Surgeries Performed by Nonexperienced Individuals: Randomized and Controlled Split-Mouth Clinical Trial. The International Journal of Oral&amp;Maxillofacial Implants, 36, 755-761. &gt;https://doi.org/10.11607/jomi.8722 
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref29">
    <label>29</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Small, P.N. and Tarnow, D.P. (2000) Gingival Recession around Implants: A 1-Year Longitudinal Prospective Study. The International Journal of Oral&amp;Maxillofacial Implants, 15, 527-532.
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref30">
    <label>30</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     D’haese, J., Ackhurst, J., Wismeijer, D., De Bruyn, H. and Tahmaseb, A. (2016) Current State of the Art of Computer-guided Implant Surgery. Periodontology 2000, 73, 121-133. &gt;https://doi.org/10.1111/prd.12175
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref31">
    <label>31</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Guimarães, C.M. (2016) Simplification and Precision in Guided Surgery for Osseointegrated Implants. Dissertation, University of Uberaba.
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref32">
    <label>32</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Sierra-Rebolledo, A., Tariba-Forero, D., Rios-Calvo, M. and Gay-Escoda, C. (2021) Effect of Undersized Drilling on the Stability of Immediate Tapered Implants in the Anterior Maxillary Sector. a Randomized Clinical Trial. Medicina Oral Patología Oral y Cirugia Bucal, 26, e187-e194. &gt;https://doi.org/10.4317/medoral.24107
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref33">
    <label>33</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Schropp, L., Wenzel, A., Kostopoulos, L. and Karring, T. (2003) Bone Healing and Soft Tissue Contour Changes Following Single-Tooth Extraction: A Clinical and Radiographic 12-Month Prospective Study. International Journal of Periodontics&amp;Restorative Dentistry, 23, 313-323.
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref34">
    <label>34</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Funato, A., Salama, M.A., Ishikawa, T., Garber, D.A. and Salama, H. (2007) Timing, Positioning, and Sequential Staging in Esthetic Implant Therapy: A Four-Dimensional Perspective. International Journal of Periodontics&amp;Restorative Dentistry, 27, 313-323.
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref35">
    <label>35</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Gomez-Roman, G. (2001) Influence of Flap Design on Peri-Implant Interproximal Crestal Bone Loss around Single-Tooth Implants. The International Journal of Oral&amp;Maxillofacial Implants, 16, 61-67.
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref36">
    <label>36</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Abrahamsson, I., Berglundh, T. and Lindhe, J. (1997) The Mucosal Barrier Following Abutment Dis/Reconnection: An Experimental Study in Dogs. Journal of Clinical Periodontology, 24, 568-572. &gt;https://doi.org/10.1111/j.1600-051x.1997.tb00230.x
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref37">
    <label>37</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Pohl, V., Fürhauser, L., Haas, R. and Pohl, S. (2020) Gingival Recession Behavior with Immediate Implant Placement in the Anterior Maxilla with Buccal Dehiscence without Additional Augmentation—A Pilot Study. Clinical Oral Investigations, 24, 1455-1464. &gt;https://doi.org/10.1007/s00784-019-03176-5
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref38">
    <label>38</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Rompen, E., Raepsaet, N., Domken, O., Touati, B. and Van Dooren, E. (2007) Soft Tissue Stability at the Facial Aspect of Gingivally Converging Abutments in the Esthetic Zone: A Pilot Clinical Study. The Journal of Prosthetic Dentistry, 97, S119-S125. &gt;https://doi.org/10.1016/s0022-3913(07)60015-8
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref39">
    <label>39</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Buser, D., Martin, W. and Belser, U.C. (2004) Optimizing Esthetics for Implant Restorations in the Anterior Maxilla: Anatomic and Surgical Considerations. The International Journal of Oral&amp;Maxillofacial Implants, 19, 43-61.
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref40">
    <label>40</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Levine, R.A., Ganeles, J., Gonzaga, L., Kan, J.K., Randel, H., Evans, C.D. and Chen, S.T. (2017) 10 Keys for Successful Esthetic-Zone Single Immediate Implants. Compendium of Continuing Education in Dentistry, 38, 248-260.
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref41">
    <label>41</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Chen, P. and Nikoyan, L. (2021) Guided Implant Surgery: A Technique Whose Time Has Come. Dental Clinics of North America, 65, 67-80. &gt;https://doi.org/10.1016/j.cden.2020.09.005
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref42">
    <label>42</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Kernen, F., Kramer, J., Wanner, L., Wismeijer, D., Nelson, K. and Flügge, T. (2020) A Review of Virtual Planning Software for Guided Implant Surgery—Data Import and Visualization, Drill Guide Design and Manufacturing. BMC Oral Health, 20, Article No. 251. &gt;https://doi.org/10.1186/s12903-020-01208-1
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref43">
    <label>43</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Báez-Marrero, N., Rafel, J.L., Rodríguez-Cárdenas, Y.A., Aliaga-Del Castillo, A., Dias-Da Silveira, H.L. and Arriola-Guillén, L.E. (2022) Accuracy of Computer-Assisted Surgery in Immediate Implant Placement: An Experimental Study. Journal of Indian Society of Periodontology, 26, 219-223. &gt;https://doi.org/10.4103/jisp.jisp_763_20
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref44">
    <label>44</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Pessoa, R., Siqueira, R., Li, J., Saleh, I., Meneghetti, P., Bezerra, F., et al. (2021) The Impact of Surgical Guide Fixation and Implant Location on Accuracy of Static Computer-Assisted Implant Surgery. Journal of Prosthodontics, 31, 155-164. &gt;https://doi.org/10.1111/jopr.13371
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref45">
    <label>45</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Henprasert, P., Dawson, D.V., El-Kerdani, T., Song, X., Couso-Queiruga, E. and Holloway, J.A. (2020) Comparison of the Accuracy of Implant Position Using Surgical Guides Fabricated by Additive and Subtractive Techniques. Journal of Prosthodontics, 29, 534-541. &gt;https://doi.org/10.1111/jopr.13161
    </mixed-citation>
   </ref>
   <ref id="scirp.144682-ref46">
    <label>46</label>
    <mixed-citation publication-type="other" xlink:type="simple">
     Dioguardi, M., Spirito, F., Quarta, C., Sovereto, D., Basile, E., Ballini, A., et al. (2023) Guided Dental Implant Surgery: Systematic Review. Journal of Clinical Medicine, 12, Article No. 1490. &gt;https://doi.org/10.3390/jcm12041490
    </mixed-citation>
   </ref>
  </ref-list>
 </back>
</article>