<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v3.0 20080202//EN" "http://dtd.nlm.nih.gov/publishing/3.0/journalpublishing3.dtd">
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="3.0" xml:lang="en" article-type="research article">
 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">
    ojapps
   </journal-id>
   <journal-title-group>
    <journal-title>
     Open Journal of Applied Sciences
    </journal-title>
   </journal-title-group>
   <issn pub-type="epub">
    2165-3917
   </issn>
   <issn publication-format="print">
    2165-3925
   </issn>
   <publisher>
    <publisher-name>
     Scientific Research Publishing
    </publisher-name>
   </publisher>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="doi">
    10.4236/ojapps.2025.155105
   </article-id>
   <article-id pub-id-type="publisher-id">
    ojapps-143046
   </article-id>
   <article-categories>
    <subj-group subj-group-type="heading">
     <subject>
      Articles
     </subject>
    </subj-group>
    <subj-group subj-group-type="Discipline-v2">
     <subject>
      Biomedical 
     </subject>
     <subject>
       Life Sciences, Chemistry 
     </subject>
     <subject>
       Materials Science, Computer Science 
     </subject>
     <subject>
       Communications, Engineering, Physics 
     </subject>
     <subject>
       Mathematics
     </subject>
    </subj-group>
   </article-categories>
   <title-group>
    Initial Model for the Impact of Social Distancing on COVID-19 Spread
   </title-group>
   <contrib-group>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Genghmun
      </surname>
      <given-names>
       Eng
      </given-names>
     </name>
    </contrib>
   </contrib-group> 
   <aff id="affnull">
    <addr-line>
     aPhD Physics 1978, University of Illinois at Urbana-Champaign, Urbana, IL, USA
    </addr-line> 
   </aff> 
   <pub-date pub-type="epub">
    <day>
     09
    </day> 
    <month>
     05
    </month>
    <year>
     2025
    </year>
   </pub-date> 
   <volume>
    15
   </volume> 
   <issue>
    05
   </issue>
   <fpage>
    1507
   </fpage>
   <lpage>
    1527
   </lpage>
   <history>
    <date date-type="received">
     <day>
      30,
     </day>
     <month>
      March
     </month>
     <year>
      2025
     </year>
    </date>
    <date date-type="published">
     <day>
      28,
     </day>
     <month>
      March
     </month>
     <year>
      2025
     </year> 
    </date> 
    <date date-type="accepted">
     <day>
      28,
     </day>
     <month>
      May
     </month>
     <year>
      2025
     </year> 
    </date>
   </history>
   <permissions>
    <copyright-statement>
     © Copyright 2014 by authors and Scientific Research Publishing Inc. 
    </copyright-statement>
    <copyright-year>
     2014
    </copyright-year>
    <license>
     <license-p>
      This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/
     </license-p>
    </license>
   </permissions>
   <abstract>
    The initial stages of the CoVID-19 coronavirus pandemic all around the world exhibited a nearly exponential rise in the number of infections with time. Planners, governments, and agencies scrambled to figure out “How much? How bad?” and how to effectively treat the potentially large numbers of simultaneously sick people. Modeling the CoVID-19 pandemic using an exponential rise implicitly assumes a nearly unlimited population of uninfected persons (“dilute pandemic”). Once a significant fraction of the population is infected (“saturated pandemic”), an exponential growth no longer applies. A new model is developed here, which modifies the standard exponential growth function to account for factors such as Social Distancing. A Social Mitigation Parameter [SMP] 
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      <msub> 
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      </msub> 
     </mrow> 
    </math> is introduced to account for these types of society-wide changes, which can modify the standard exponential growth function, as follows:
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       N
      </mi>
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       =
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      </msub> 
      <mi>
       exp
      </mi>
      <mrow>
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        [
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         +
        </mo>
        <mrow>
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           <mi>
            K
           </mi> 
           <mi>
            o
           </mi> 
          </msub> 
          <mi>
           t
          </mi>
         </mrow>
         <mo>
          /
         </mo>
         <mrow> 
          <mrow>
           <mo>
            (
           </mo> 
           <mrow> 
            <mn>
             1
            </mn>
            <mo>
             +
            </mo>
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             <mi>
              α
             </mi> 
             <mi>
              S
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            </msub> 
            <mi>
             t
            </mi>
           </mrow> 
           <mo>
            )
           </mo>
          </mrow>
         </mrow>
        </mrow> 
       </mrow> 
       <mo>
        ]
       </mo>
      </mrow>
     </mrow> 
    </math> .The doubling-time 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
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       </mi> 
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        </mi>
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      </msub> 
      <mo>
       =
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        <mrow>
         <mo>
          (
         </mo> 
         <mrow> 
          <mi>
           ln
          </mi>
          <mn>
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          </mn>
         </mrow> 
         <mo>
          )
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        </mrow>
       </mrow>
       <mo>
        /
       </mo>
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        <msub> 
         <mi>
          K
         </mi> 
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          o
         </mi> 
        </msub> 
       </mrow>
      </mrow> 
     </mrow> 
    </math> can also be used to substitute for 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
        K
       </mi> 
       <mi>
        o
       </mi> 
      </msub> 
     </mrow> 
    </math> , giving a 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mrow>
       <mo>
        {
       </mo> 
       <mrow> 
        <msub> 
         <mi>
          t
         </mi> 
         <mrow> 
          <mi>
           d
          </mi>
          <mi>
           b
          </mi>
          <mi>
           l
          </mi>
         </mrow> 
        </msub> 
        <mo>
         ,
        </mo>
        <msub> 
         <mi>
          α
         </mi> 
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       </mrow> 
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     </mrow> 
    </math> parameter pair for comparing to actual CoVID-19 data. This model shows how the number of CoVID-19 infections can self-limit before reaching a saturated pandemic level. It also provides estimates for: 1) the timing of the pandemic peak, 2) the maximum number of new daily cases that would be expected, and 3) the expected total number of CoVID-19 cases. This model shows fairly good agreement with the presently available CoVID-19 pandemic data for several individual States, and for the USA as a whole (6 Figures), as well as for various countries around the World (9 Figures). An augmented model with two Mitigation Parameters, 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
        α
       </mi> 
       <mi>
        S
       </mi> 
      </msub> 
     </mrow> 
    </math> and 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
        β
       </mi> 
       <mi>
        S
       </mi> 
      </msub> 
     </mrow> 
    </math> , is also developed, which can give better agreement with the daily new CoVID-19 data. Data-to-model comparisons also indicate that using 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
        α
       </mi> 
       <mi>
        S
       </mi> 
      </msub> 
     </mrow> 
    </math> by itself likely provides a worst-case estimate, while using both 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
        α
       </mi> 
       <mi>
        S
       </mi> 
      </msub> 
     </mrow> 
    </math> and 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
        β
       </mi> 
       <mi>
        S
       </mi> 
      </msub> 
     </mrow> 
    </math> likely provides a best-case estimate for the CoVID-19 spread.
   </abstract>
   <kwd-group> 
    <kwd>
     COVID-19
    </kwd> 
    <kwd>
      Pandemic Modeling
    </kwd> 
    <kwd>
      Social Distancing
    </kwd> 
    <kwd>
      Social Mitigation
    </kwd>
   </kwd-group>
  </article-meta>
 </front>
 <body>
  <sec id="s1">
   <title>1. Introduction</title>
   <p>The Coronavirus 2019 disease (CoVID-19), caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) pathogen, has become a world-wide pandemic. In many localities, the number of cases 
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      </mi> 
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         ( 
       </mo> 
       <mi>
         t 
       </mi> 
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         ) 
       </mo> 
      </mrow> 
     </mrow> 
    </math> was found to have an initial period of nearly exponential growth:</p>
   <p>
    <math display="inline" xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        N 
      </mi> 
      <mrow> 
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       </mo> 
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         t 
       </mi> 
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       </mo> 
      </mrow> 
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        = 
      </mo> 
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         ] 
       </mo> 
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     </mrow> 
    </math>, (1)</p>
   <p>
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      </mo> 
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            2 
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    </math>, (2)</p>
   <p>aside of the first few cases, which may be untraceable. In Equations (1)-(2), 
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    </math> is the initial number of infections at the 
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    </math> start of data tracking, 
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    </math> is an exponential growth factor, and 
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    </math> is the doubling-time. Each locality can have its own 
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    </math> values, with both 
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    </math> being nearly constant during this initial period of CoVID-19 spread.</p>
   <p>Standard epidemiology identifies the number of people 
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    </math> a known infected individual had recent contact with. Contacts of that 
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    </math> group are tracked next, followed by additional tracking stages. This process sets the 
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    </math> value.</p>
   <p>Society-wide Mitigation Measures such as: 1) Social Distancing, 2) wearing face masks in public, 3) prohibiting large gatherings, 4) implementing large-scale population testing, 5) disinfecting high-touch surfaces in public areas, 6) enhanced cleaning of items brought into homes, and 7) minimizing human contact with likely virus-containing materials and matter; all can help reduce 
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    </math> growth. These Mitigation Measures can modify the Equation (1) epidemiology model by causing the local 
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    </math> values to lengthen.</p>
   <p>In order to model these Mitigation Measures, 
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    </math> and 
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    </math> become explicit functions of time, 
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    </math>. Using a linear function for 
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    </math> lengthening is one of the simplest time-varying extensions. A linear function of time also corresponds to the first term of a Taylors’ Series expansion of some more general 
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    </math> analytic function, giving this epidemiology extension:</p>
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    </math>, (3)</p>
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           </mi> 
          </msub> 
          <mi>
            t 
          </mi> 
         </mrow> 
         <mo>
           ) 
         </mo> 
        </mrow> 
       </mrow> 
      </mrow> 
     </mrow> 
    </math>. (4)</p>
   <p>The 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        t 
      </mi> 
      <mo>
        = 
      </mo> 
      <mn>
        0 
      </mn> 
     </mrow> 
    </math> initial values for 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mi>
         D 
       </mi> 
      </msub> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mi>
         t 
       </mi> 
       <mo>
         ) 
       </mo> 
      </mrow> 
     </mrow> 
    </math> and 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         K 
       </mi> 
       <mi>
         D 
       </mi> 
      </msub> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mi>
         t 
       </mi> 
       <mo>
         ) 
       </mo> 
      </mrow> 
     </mrow> 
    </math> become the new constants 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msub> 
     </mrow> 
    </math> and 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         K 
       </mi> 
       <mi>
         o 
       </mi> 
      </msub> 
     </mrow> 
    </math>, which characterize the initial exponential growth phase. The 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math> coefficient in Equation (3) is a new Social Mitigation Parameter [SMP] that helps quantify the effectiveness of the society-wide Mitigation Measures as a whole.</p>
   <p>The 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math> value expresses how well non-infected people manage to avoid the virus contagion. As a lumped parameter, it likely reflects an average value over many processes, known and unknown, which comprise Social Mitigation, to supplement the contact-to-contact tracking that initially sets 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msub> 
     </mrow> 
    </math> or 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         K 
       </mi> 
       <mi>
         o 
       </mi> 
      </msub> 
     </mrow> 
    </math>.</p>
   <p>Substituting Equation (4) into Equation (1) gives:</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        N 
      </mi> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mi>
         t 
       </mi> 
       <mo>
         ) 
       </mo> 
      </mrow> 
      <mo>
        = 
      </mo> 
      <msub> 
       <mi>
         N 
       </mi> 
       <mi>
         o 
       </mi> 
      </msub> 
      <mi>
        exp 
      </mi> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mo>
          + 
        </mo> 
        <mrow> 
         <mrow> 
          <msub> 
           <mi>
             K 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
          <mi>
            t 
          </mi> 
         </mrow> 
         <mo>
           / 
         </mo> 
         <mrow> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mrow> 
            <mn>
              1 
            </mn> 
            <mo>
              + 
            </mo> 
            <msub> 
             <mi>
               α 
             </mi> 
             <mi>
               S 
             </mi> 
            </msub> 
            <mi>
              t 
            </mi> 
           </mrow> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
     </mrow> 
    </math>, (5)</p>
   <p>as one of the simplest models for CoVID-19 spread. A pure exponential growth (or decay) has no memory, while Equation (5) for 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
      <mo>
        &gt; 
      </mo> 
      <mn>
        0 
      </mn> 
     </mrow> 
    </math>, has a memory. The 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        t 
      </mi> 
      <mo>
        = 
      </mo> 
      <mn>
        0 
      </mn> 
     </mrow> 
    </math> start time of first mitigation changes the future history. To include 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        t 
      </mi> 
      <mo>
        &lt; 
      </mo> 
      <mn>
        0 
      </mn> 
     </mrow> 
    </math> requires replacing Equation (3) by 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mi>
         D 
       </mi> 
      </msub> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mi>
         t 
       </mi> 
       <mo>
         ) 
       </mo> 
      </mrow> 
      <mo>
        ≡ 
      </mo> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msub> 
      <mo> 
      </mo> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mrow> 
        <mn>
          1 
        </mn> 
        <mo>
          + 
        </mo> 
        <mtext>
          max 
        </mtext> 
        <mrow> 
         <mo>
           [ 
         </mo> 
         <mrow> 
          <mn>
            0 
          </mn> 
          <mo>
            , 
          </mo> 
          <msub> 
           <mi>
             α 
           </mi> 
           <mi>
             S 
           </mi> 
          </msub> 
          <mi>
            t 
          </mi> 
         </mrow> 
         <mo>
           ] 
         </mo> 
        </mrow> 
       </mrow> 
       <mo>
         ) 
       </mo> 
      </mrow> 
     </mrow> 
    </math>, which has a corner at 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        t 
      </mi> 
      <mo>
        = 
      </mo> 
      <mn>
        0 
      </mn> 
     </mrow> 
    </math> that preserves the memory of when mitigation first started.</p>
  </sec><sec id="s2">
   <title>
    <xref ref-type="bibr" rid="scirp.143046-"></xref>2. Model Features</title>
   <p>The Equation (1) exponential growth pandemic model implicitly assumes a large uninfected population allowing the disease to easily spread (“dilute pandemic”). When almost everybody is infected (“saturated pandemic”), exponential growth shuts off, and Equation (1) no longer applies.</p>
   <p>On 3/10/2020, German Chancellor Angela Merkel <xref ref-type="bibr" rid="scirp.143046-1">
     [1]
    </xref> noted that she “estimates that 60% to 70% of the German population will contract the coronavirus”, indicating that saturated pandemic models were being considered as a worst-case.</p>
   <p>Even that worst-case condition assumes: 1) recovered coronavirus patients are no longer infectious, and 2) surviving a CoVID-19 infection confers absolute immunity to re-infection. More recently, South Korea <xref ref-type="bibr" rid="scirp.143046-2">
     [2]
    </xref> found 91 cases of clinically recovered patients later testing as CoVID-19 positive. They may also shed viable coronaviruses in their phlegm and fecal matter, furthering disease spread. Although these effects are not modeled here, those additional transmission modes could turn a 60% - 70% hope into a calculated 99+% consequence.</p>
   <p>These factors show why CoVID-19 modeling beyond Equation (1) is needed, especially to see if society-wide Mitigation Measures can naturally halt disease spread, without necessitating a saturated pandemic condition. We show next that Equation (5) allows for this pandemic shut-off, even for the dilute pandemic case. Since both 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         K 
       </mi> 
       <mi>
         o 
       </mi> 
      </msub> 
     </mrow> 
    </math> and 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math> in Equation (5) have the same units, their ratio is dimensionless. The long-term limit of Equation (5) gives:</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <munder> 
       <mrow> 
        <mi>
          lim 
        </mi> 
       </mrow> 
       <mrow> 
        <mi>
          t 
        </mi> 
        <mo>
          → 
        </mo> 
        <mo>
          + 
        </mo> 
        <mi>
          ∞ 
        </mi> 
       </mrow> 
      </munder> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mrow> 
         <mrow> 
          <mi>
            N 
          </mi> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mi>
             t 
           </mi> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
         <mo>
           / 
         </mo> 
         <mrow> 
          <msub> 
           <mi>
             N 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
         </mrow> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
      <mo>
        = 
      </mo> 
      <mi>
        exp 
      </mi> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mo>
          + 
        </mo> 
        <mrow> 
         <mrow> 
          <msub> 
           <mi>
             K 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
         </mrow> 
         <mo>
           / 
         </mo> 
         <mrow> 
          <msub> 
           <mi>
             α 
           </mi> 
           <mi>
             S 
           </mi> 
          </msub> 
         </mrow> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
     </mrow> 
    </math>, (6)</p>
   <p>setting an average value for the total number of all follow-on infections arising from a single individual. Since it depends only on the ratio of the original pandemic growth factor 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         K 
       </mi> 
       <mi>
         o 
       </mi> 
      </msub> 
     </mrow> 
    </math> to the 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math> SMP, this model shows the impact of accounting for a broader environment beyond individual contact tracking.</p>
   <p>The early spread of CoVID-19 cases outside of China, and the early USA CoVID-19 data <xref ref-type="bibr" rid="scirp.143046-3">
     [3]
    </xref> both had nearly exponential rises, as shown in <xref ref-type="fig" rid="fig1">
     Figure 1
    </xref>. A purely exponential rise gives a straight line on a log-plot {log(# of cases) vs linear time}. The initial doubling-time for the USA was 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msub> 
      <mo>
        ≈ 
      </mo> 
      <mn>
        2.02 
      </mn> 
      <mtext>
          
      </mtext> 
      <mtext>
        days 
      </mtext> 
     </mrow> 
    </math>, giving 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         K 
       </mi> 
       <mi>
         o 
       </mi> 
      </msub> 
      <mo>
        ≈ 
      </mo> 
      <mrow> 
       <mrow> 
        <mn>
          0.343 
        </mn> 
       </mrow> 
       <mo>
         / 
       </mo> 
       <mrow> 
        <mtext>
          day 
        </mtext> 
       </mrow> 
      </mrow> 
     </mrow> 
    </math> using Equations (1)-(2). This initial CoVID-19 data was prior to any significant Mitigation Measures being implemented.</p>
   <fig id="fig1" position="float">
    <label>Figure 1</label>
    <caption>
     <title>Figure 1. Early CoVID-19 Cases: (a) Outside of China, and (b) Just in the US. Both graphs show nearly exponential growth.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2313106-rId126.jpeg?20250603091015" />
   </fig>
   <p>On March 19, 2020, Governor Gavin Newsom of California ordered a CoVID-19 “stay-at-home” lockdown of virtually all of California’s nearly 40 million residents. Similar statewide CoVID-19 lockdowns were ordered by the Governors of Illinois, New York, Indiana, Michigan, Ohio, Washington, West Virginia and Wisconsin.</p>
   <p>The slowing of CoVID-19 spread by implementing large-scale societal Mitigation Measures can be fairly rapid, as illustrated by the USA CoVID-19 data of <xref ref-type="fig" rid="fig2">
     Figure 2
    </xref>, which covers March 2020.</p>
   <p>The impact of these multi-state Mitigation Measures is evident in <xref ref-type="fig" rid="fig2">
     Figure 2
    </xref> as a sudden transition on the log-plot from a straight-line to having downward curvature, which the 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math> Social Mitigation Parameter (SMP) aims to quantify. The local slope in <xref ref-type="fig" rid="fig2">
     Figure 2
    </xref> also decreases right after the onset of Mitigation Measures, indicating further slowing of CoVID-19 spread.</p>
   <p>A well-documented South Korean coronavirus cluster can also be used to help estimate the expected size of the 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math> SMP. That CoVID-19 cluster determined that a single infected person at the Shinjeongji Church caused infection of about 4482 people within the 47-day time interval between January 20, 2020 and March 8, 2020. Using 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         K 
       </mi> 
       <mi>
         o 
       </mi> 
      </msub> 
     </mrow> 
    </math> from <xref ref-type="fig" rid="fig1(b)">
     Figure 1(b)
    </xref> provides this 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math> estimate:</p>
   <p>
    <math display="inline" xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mtext>
        ln 
      </mtext> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mrow> 
        <mn>
          4.482 
        </mn> 
       </mrow> 
       <mo>
         ) 
       </mo> 
      </mrow> 
      <mo>
        ≈ 
      </mo> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mrow> 
        <mrow> 
         <mrow> 
          <mn>
            0.343 
          </mn> 
         </mrow> 
         <mo>
           / 
         </mo> 
         <mrow> 
          <mtext>
            day 
          </mtext> 
         </mrow> 
        </mrow> 
       </mrow> 
       <mo>
         ) 
       </mo> 
      </mrow> 
      <mrow> 
       <mrow> 
        <mrow> 
         <mo>
           ( 
         </mo> 
         <mrow> 
          <mn>
            47 
          </mn> 
          <mtext>
              
          </mtext> 
          <mtext>
            days 
          </mtext> 
         </mrow> 
         <mo>
           ) 
         </mo> 
        </mrow> 
       </mrow> 
       <mo>
         / 
       </mo> 
       <mrow> 
        <mrow> 
         <mo>
           [ 
         </mo> 
         <mrow> 
          <mn>
            1 
          </mn> 
          <mo>
            + 
          </mo> 
          <msub> 
           <mi>
             α 
           </mi> 
           <mi>
             S 
           </mi> 
          </msub> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mrow> 
            <mn>
              47 
            </mn> 
            <mtext>
                
            </mtext> 
            <mtext>
              days 
            </mtext> 
           </mrow> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
         <mo>
           ] 
         </mo> 
        </mrow> 
       </mrow> 
      </mrow> 
     </mrow> 
    </math>, (7)</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
      <mo>
        = 
      </mo> 
      <mrow> 
       <mrow> 
        <mn>
          0.01952 
        </mn> 
       </mrow> 
       <mo>
         / 
       </mo> 
       <mrow> 
        <mtext>
          day 
        </mtext> 
       </mrow> 
      </mrow> 
      <mo>
        ≈ 
      </mo> 
      <mrow> 
       <mrow> 
        <mn>
          0.02 
        </mn> 
       </mrow> 
       <mo>
         / 
       </mo> 
       <mrow> 
        <mtext>
          day 
        </mtext> 
       </mrow> 
      </mrow> 
     </mrow> 
    </math>, (8)</p>
   <p>which is indicative of minimal mitigation. If additional deliberate mitigation measures doubled 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math> to 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
      <mo>
        ≈ 
      </mo> 
      <mrow> 
       <mrow> 
        <mn>
          0.04 
        </mn> 
       </mrow> 
       <mo>
         / 
       </mo> 
       <mrow> 
        <mtext>
          day 
        </mtext> 
       </mrow> 
      </mrow> 
     </mrow> 
    </math>, Equation (6) would give:</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <munder> 
       <mrow> 
        <mi>
          lim 
        </mi> 
       </mrow> 
       <mrow> 
        <mi>
          t 
        </mi> 
        <mo>
          → 
        </mo> 
        <mo>
          + 
        </mo> 
        <mi>
          ∞ 
        </mi> 
       </mrow> 
      </munder> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mrow> 
         <mrow> 
          <mi>
            N 
          </mi> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mi>
             t 
           </mi> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
         <mo>
           / 
         </mo> 
         <mrow> 
          <msub> 
           <mi>
             N 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
         </mrow> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
      <mo>
        = 
      </mo> 
      <mi>
        exp 
      </mi> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mo>
          + 
        </mo> 
        <mfrac> 
         <mrow> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mrow> 
            <mrow> 
             <mrow> 
              <mn>
                0.343 
              </mn> 
             </mrow> 
             <mo>
               / 
             </mo> 
             <mrow> 
              <mtext>
                day 
              </mtext> 
             </mrow> 
            </mrow> 
           </mrow> 
           <mo>
             ) 
           </mo> 
          </mrow> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mrow> 
            <mn>
              47 
            </mn> 
            <mtext>
                
            </mtext> 
            <mtext>
              days 
            </mtext> 
           </mrow> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
         <mrow> 
          <mn>
            1 
          </mn> 
          <mo>
            + 
          </mo> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mrow> 
            <mrow> 
             <mrow> 
              <mn>
                0.04 
              </mn> 
             </mrow> 
             <mo>
               / 
             </mo> 
             <mrow> 
              <mtext>
                day 
              </mtext> 
             </mrow> 
            </mrow> 
           </mrow> 
           <mo>
             ) 
           </mo> 
          </mrow> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mrow> 
            <mn>
              47 
            </mn> 
            <mtext>
                
            </mtext> 
            <mtext>
              days 
            </mtext> 
           </mrow> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
        </mfrac> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
      <mo>
        ≈ 
      </mo> 
      <mn>
        270 
      </mn> 
     </mrow> 
    </math>, (9)</p>
   <p>for the number of infections per person, a 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mn>
        16.6 
      </mn> 
      <mi>
        X 
      </mi> 
     </mrow> 
    </math> reduction from 4482.</p>
   <fig id="fig2" position="float">
    <label>Figure 2</label>
    <caption>
     <title>Figure 2. USA CoVID-19 data, pre-vs-post mid-March 2020. Multi-State Mitigation Measures slowed growth, transitioning from straight-line to downward curvature.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2313106-rId146.jpeg?20250603091015" />
   </fig>
   <p>Since 
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      <mi>
        N 
      </mi> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mi>
         t 
       </mi> 
       <mo>
         ) 
       </mo> 
      </mrow> 
     </mrow> 
    </math> in Equation (5) represents a total number of cases, it is similar to a cumulative distribution function (cdf), which is used in reliability and also has time as its fundamental variable. The derivative of Equation (5), 
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      <mrow> 
       <mrow> 
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          d 
        </mtext> 
        <mi>
          N 
        </mi> 
        <mrow> 
         <mo>
           ( 
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         <mi>
           t 
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         <mo>
           ) 
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       <mo>
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        <mtext>
          d 
        </mtext> 
        <mi>
          t 
        </mi> 
       </mrow> 
      </mrow> 
     </mrow> 
    </math>, is analogous to an unnormalized probability density function (pdf), which can be used to predict a pandemic peak:</p>
   <p>
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      <mtr> 
       <mtd> 
        <mrow> 
         <mo>
           { 
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         <mrow> 
          <mi>
            p 
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          </mi> 
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            f 
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         </mrow> 
         <mo>
           } 
         </mo> 
        </mrow> 
        <mo>
          ≡ 
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         <mtext>
           d 
         </mtext> 
         <mrow> 
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            d 
          </mtext> 
          <mi>
            t 
          </mi> 
         </mrow> 
        </mfrac> 
        <mrow> 
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           [ 
         </mo> 
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          <mfrac> 
           <mrow> 
            <mi>
              N 
            </mi> 
            <mrow> 
             <mo>
               ( 
             </mo> 
             <mi>
               t 
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               ) 
             </mo> 
            </mrow> 
           </mrow> 
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            <msub> 
             <mi>
               N 
             </mi> 
             <mi>
               o 
             </mi> 
            </msub> 
           </mrow> 
          </mfrac> 
         </mrow> 
         <mo>
           ] 
         </mo> 
        </mrow> 
        <mo>
          = 
        </mo> 
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         <mtext>
           d 
         </mtext> 
         <mrow> 
          <mtext>
            d 
          </mtext> 
          <mi>
            t 
          </mi> 
         </mrow> 
        </mfrac> 
        <mrow> 
         <mo>
           { 
         </mo> 
         <mrow> 
          <mtext>
            exp 
          </mtext> 
          <mrow> 
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             [ 
           </mo> 
           <mrow> 
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              + 
            </mo> 
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              <msub> 
               <mi>
                 K 
               </mi> 
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                 o 
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                t 
              </mi> 
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               / 
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                  1 
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                  + 
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                 </mi> 
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                 ) 
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             ] 
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           } 
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            ) 
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         <mn>
           2 
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        </msup> 
        <mtext>
          exp 
        </mtext> 
        <mrow> 
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           [ 
         </mo> 
         <mrow> 
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            + 
          </mo> 
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               K 
             </mi> 
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             </mi> 
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              t 
            </mi> 
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             / 
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               ( 
             </mo> 
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                1 
              </mn> 
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                + 
              </mo> 
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               </mi> 
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                 S 
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                t 
              </mi> 
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               ) 
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            </mrow> 
           </mrow> 
          </mrow> 
         </mrow> 
         <mo>
           ] 
         </mo> 
        </mrow> 
       </mtd> 
      </mtr> 
     </mtable> 
    </math>, (10)</p>
   <p>
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      <mrow> 
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         { 
       </mo> 
       <mrow> 
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        </mi> 
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         } 
       </mo> 
      </mrow> 
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        = 
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        + 
      </mo> 
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       <mi>
         K 
       </mi> 
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               ( 
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               ) 
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               N 
             </mi> 
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               o 
             </mi> 
            </msub> 
           </mrow> 
          </mfrac> 
         </mrow> 
         <mo>
           ] 
         </mo> 
        </mrow> 
       </mrow> 
       <mo>
         / 
       </mo> 
       <mrow> 
        <msup> 
         <mrow> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mrow> 
            <mn>
              1 
            </mn> 
            <mo>
              + 
            </mo> 
            <msub> 
             <mi>
               α 
             </mi> 
             <mi>
               S 
             </mi> 
            </msub> 
            <mi>
              t 
            </mi> 
           </mrow> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
         <mn>
           2 
         </mn> 
        </msup> 
       </mrow> 
      </mrow> 
     </mrow> 
    </math>, (11)</p>
   <p>The time 
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      <msub> 
       <mi>
         t 
       </mi> 
       <mi>
         P 
       </mi> 
      </msub> 
     </mrow> 
    </math> of the pandemic peak is set by:</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mfrac> 
       <mtext>
         d 
       </mtext> 
       <mrow> 
        <mtext>
          d 
        </mtext> 
        <mi>
          t 
        </mi> 
       </mrow> 
      </mfrac> 
      <mrow> 
       <mo>
         { 
       </mo> 
       <mrow> 
        <mi>
          p 
        </mi> 
        <mi>
          d 
        </mi> 
        <mi>
          f 
        </mi> 
       </mrow> 
       <mo>
         } 
       </mo> 
      </mrow> 
      <mo>
        ≡ 
      </mo> 
      <mn>
        0 
      </mn> 
     </mrow> 
    </math>, (12)</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mi>
         P 
       </mi> 
      </msub> 
      <mo>
        = 
      </mo> 
      <mfrac> 
       <mn>
         1 
       </mn> 
       <mn>
         2 
       </mn> 
      </mfrac> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mrow> 
         <mrow> 
          <msub> 
           <mi>
             K 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
         </mrow> 
         <mo>
           / 
         </mo> 
         <mrow> 
          <msub> 
           <mi>
             α 
           </mi> 
           <mi>
             S 
           </mi> 
          </msub> 
         </mrow> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
      <mo>
        − 
      </mo> 
      <mn>
        1 
      </mn> 
     </mrow> 
    </math>, (13)</p>
   <p>where the Equation (13) simplification arises from the Equation (12) constraint. Substituting 
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      <msub> 
       <mi>
         K 
       </mi> 
       <mi>
         o 
       </mi> 
      </msub> 
      <mo>
        = 
      </mo> 
      <mrow> 
       <mrow> 
        <mn>
          0.343 
        </mn> 
       </mrow> 
       <mo>
         / 
       </mo> 
       <mrow> 
        <mtext>
          day 
        </mtext> 
       </mrow> 
      </mrow> 
     </mrow> 
    </math> and 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
      <mo>
        = 
      </mo> 
      <mrow> 
       <mrow> 
        <mn>
          0.02 
        </mn> 
       </mrow> 
       <mo>
         / 
       </mo> 
       <mrow> 
        <mtext>
          day 
        </mtext> 
       </mrow> 
      </mrow> 
     </mrow> 
    </math> from Equation (8) into Equation (13) gives 
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      <msub> 
       <mi>
         t 
       </mi> 
       <mi>
         P 
       </mi> 
      </msub> 
      <mo>
        ≈ 
      </mo> 
      <mn>
        379 
      </mn> 
      <mtext>
          
      </mtext> 
      <mtext>
        days 
      </mtext> 
     </mrow> 
    </math>. Increasing mitigation to 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
      <mo>
        = 
      </mo> 
      <mrow> 
       <mrow> 
        <mn>
          0.04 
        </mn> 
       </mrow> 
       <mo>
         / 
       </mo> 
       <mrow> 
        <mtext>
          day 
        </mtext> 
       </mrow> 
      </mrow> 
     </mrow> 
    </math>, keeping the same 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         K 
       </mi> 
       <mi>
         o 
       </mi> 
      </msub> 
      <mo>
        = 
      </mo> 
      <mrow> 
       <mrow> 
        <mn>
          0.343 
        </mn> 
       </mrow> 
       <mo>
         / 
       </mo> 
       <mrow> 
        <mtext>
          day 
        </mtext> 
       </mrow> 
      </mrow> 
     </mrow> 
    </math>, now gives 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mi>
         P 
       </mi> 
      </msub> 
      <mo>
        ≈ 
      </mo> 
      <mn>
        82 
      </mn> 
      <mtext>
          
      </mtext> 
      <mtext>
        days 
      </mtext> 
     </mrow> 
    </math>, which is almost a 4.6 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mi>
       X 
     </mi> 
    </math> reduction in the pandemic peak timing for doubling the Social Mitigation effect from its original baseline value. These examples highlight the tremendous impact that even a small amount of enhanced Social Mitigation can have.</p>
   <p>While the 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
      <mo>
        = 
      </mo> 
      <mn>
        0 
      </mn> 
     </mrow> 
    </math> limit of Equation (11) recovers the Equation (1) standard exponential growth, both the 
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      <mrow> 
       <mo>
         { 
       </mo> 
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          d 
        </mi> 
        <mi>
          f 
        </mi> 
       </mrow> 
       <mo>
         } 
       </mo> 
      </mrow> 
     </mrow> 
    </math> and 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mrow> 
         <mrow> 
          <mi>
            N 
          </mi> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mi>
             t 
           </mi> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
         <mo>
           / 
         </mo> 
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          <msub> 
           <mi>
             N 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
         </mrow> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
     </mrow> 
    </math> growth are then unbounded. However, even a small 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
      <mo>
        &gt; 
      </mo> 
      <mn>
        0 
      </mn> 
     </mrow> 
    </math> value in Equation (11) will have an enormous impact on the predicted long-time behavior. Since Equation (6) showed that 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mrow> 
       <mo>
         [ 
       </mo> 
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            N 
          </mi> 
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             ( 
           </mo> 
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             t 
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             ) 
           </mo> 
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         <mo>
           / 
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             N 
           </mi> 
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             o 
           </mi> 
          </msub> 
         </mrow> 
        </mrow> 
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       <mo>
         ] 
       </mo> 
      </mrow> 
     </mrow> 
    </math> now approaches a finite value for all 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
      <mo>
        &gt; 
      </mo> 
      <mn>
        0 
      </mn> 
     </mrow> 
    </math>, this new 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mrow> 
       <mo>
         { 
       </mo> 
       <mrow> 
        <mi>
          p 
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          d 
        </mi> 
        <mi>
          f 
        </mi> 
       </mrow> 
       <mo>
         } 
       </mo> 
      </mrow> 
     </mrow> 
    </math> asymptotic limit:</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <munder> 
       <mrow> 
        <mi>
          lim 
        </mi> 
       </mrow> 
       <mrow> 
        <mi>
          t 
        </mi> 
        <mo>
          → 
        </mo> 
        <mo>
          + 
        </mo> 
        <mi>
          ∞ 
        </mi> 
        <mo>
          , 
        </mo> 
        <msub> 
         <mi>
           α 
         </mi> 
         <mi>
           S 
         </mi> 
        </msub> 
        <mo>
          &gt; 
        </mo> 
        <mn>
          0 
        </mn> 
       </mrow> 
      </munder> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mrow> 
         <mo>
           { 
         </mo> 
         <mrow> 
          <mi>
            p 
          </mi> 
          <mi>
            d 
          </mi> 
          <mi>
            f 
          </mi> 
         </mrow> 
         <mo>
           } 
         </mo> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
      <mo>
        ~ 
      </mo> 
      <mfrac> 
       <mrow> 
        <mrow> 
         <mo>
           { 
         </mo> 
         <mrow> 
          <mtext>
            Constant 
          </mtext> 
         </mrow> 
         <mo>
           } 
         </mo> 
        </mrow> 
       </mrow> 
       <mrow> 
        <msup> 
         <mrow> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mrow> 
            <msub> 
             <mi>
               α 
             </mi> 
             <mi>
               S 
             </mi> 
            </msub> 
            <mi>
              t 
            </mi> 
           </mrow> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
         <mn>
           2 
         </mn> 
        </msup> 
       </mrow> 
      </mfrac> 
     </mrow> 
    </math>, (14)</p>
   <p>also results. The 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mrow> 
       <mo>
         { 
       </mo> 
       <mrow> 
        <mi>
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        </mi> 
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          f 
        </mi> 
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    </math> that arises from this model all have an initial exponential rise, coupled with the Equation (14) “long tail” at large times, which means that new CoVID-19 cases may arise for a long time, even if significant Mitigation Measures are in place.</p>
   <p>The Equation (14) 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mrow> 
       <mo>
         { 
       </mo> 
       <mrow> 
        <mi>
          p 
        </mi> 
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        <mi>
          f 
        </mi> 
       </mrow> 
       <mo>
         } 
       </mo> 
      </mrow> 
     </mrow> 
    </math> prediction also differs substantially from the widely-used University of Washington IHME (Institute for Health Metrics and Evaluation) projections, which use symmetric Gaussians for both the 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mrow> 
       <mo>
         { 
       </mo> 
       <mrow> 
        <mi>
          p 
        </mi> 
        <mi>
          d 
        </mi> 
        <mi>
          f 
        </mi> 
       </mrow> 
       <mo>
         } 
       </mo> 
      </mrow> 
     </mrow> 
    </math> rise and fall <xref ref-type="bibr" rid="scirp.143046-4">
     [4]
    </xref>. Thus, these methods provide an alternative risk-bound for evaluating potential CoVID-19 worst-case scenarios.</p>
  </sec><sec id="s3">
   <title>
    <xref ref-type="bibr" rid="scirp.143046-"></xref>3. Determining {

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     l
    
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   ,
  
      </mo>
  
      <msub> 
   
       <mi>
        
    α
   
       </mi> 
   
       <mi>
        
    S
   
       </mi> 
  
      </msub> 
 
     </mrow>

    </math>} from CoVID-19 Data</title>
   <p>Explicit numerical values for 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mrow> 
       <mo>
         { 
       </mo> 
       <mrow> 
        <msub> 
         <mi>
           t 
         </mi> 
         <mrow> 
          <mi>
            d 
          </mi> 
          <mi>
            b 
          </mi> 
          <mi>
            l 
          </mi> 
         </mrow> 
        </msub> 
        <mo>
          , 
        </mo> 
        <msub> 
         <mi>
           α 
         </mi> 
         <mi>
           S 
         </mi> 
        </msub> 
       </mrow> 
       <mo>
         } 
       </mo> 
      </mrow> 
     </mrow> 
    </math> parameters were determined from the CoVID-19 data as follows. Rewriting Equation (5) as:</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        ln 
      </mi> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mrow> 
         <mrow> 
          <mi>
            N 
          </mi> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mi>
             t 
           </mi> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
         <mo>
           / 
         </mo> 
         <mrow> 
          <msub> 
           <mi>
             N 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
         </mrow> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
      <mo>
        = 
      </mo> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mrow> 
         <mrow> 
          <mo>
            + 
          </mo> 
          <msub> 
           <mi>
             K 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
          <mi>
            t 
          </mi> 
         </mrow> 
         <mo>
           / 
         </mo> 
         <mrow> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mrow> 
            <mn>
              1 
            </mn> 
            <mo>
              + 
            </mo> 
            <msub> 
             <mi>
               α 
             </mi> 
             <mi>
               S 
             </mi> 
            </msub> 
            <mi>
              t 
            </mi> 
           </mrow> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
      <mo>
        ≡ 
      </mo> 
      <mrow> 
       <mrow> 
        <mrow> 
         <mo>
           ( 
         </mo> 
         <mrow> 
          <mi>
            ln 
          </mi> 
          <mn>
            2 
          </mn> 
         </mrow> 
         <mo>
           ) 
         </mo> 
        </mrow> 
        <mi>
          t 
        </mi> 
       </mrow> 
       <mo>
         / 
       </mo> 
       <mrow> 
        <mrow> 
         <mo>
           [ 
         </mo> 
         <mrow> 
          <msub> 
           <mi>
             t 
           </mi> 
           <mrow> 
            <mi>
              d 
            </mi> 
            <mi>
              b 
            </mi> 
            <mi>
              l 
            </mi> 
           </mrow> 
          </msub> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mrow> 
            <mn>
              1 
            </mn> 
            <mo>
              + 
            </mo> 
            <msub> 
             <mi>
               α 
             </mi> 
             <mi>
               S 
             </mi> 
            </msub> 
            <mi>
              t 
            </mi> 
           </mrow> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
         <mo>
           ] 
         </mo> 
        </mrow> 
       </mrow> 
      </mrow> 
     </mrow> 
    </math>. (15)</p>
   <p>allowed data fitting to be done on a 
    <math display="inline" xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        Y 
      </mi> 
      <mtext>
          
      </mtext> 
      <mo>
        − 
      </mo> 
      <mtext>
          
      </mtext> 
      <mi>
        v 
      </mi> 
      <mi>
        s 
      </mi> 
      <mtext>
          
      </mtext> 
      <mo>
        − 
      </mo> 
      <mtext>
          
      </mtext> 
      <mi>
        X 
      </mi> 
     </mrow> 
    </math> log-plot, using 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        Y 
      </mi> 
      <mo>
        = 
      </mo> 
      <mtext>
        ln 
      </mtext> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mrow> 
         <mrow> 
          <mi>
            N 
          </mi> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mi>
             t 
           </mi> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
         <mo>
           / 
         </mo> 
         <mrow> 
          <msub> 
           <mi>
             N 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
         </mrow> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
     </mrow> 
    </math> as the ordinate and 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        X 
      </mi> 
      <mo>
        ↔ 
      </mo> 
      <mi>
        t 
      </mi> 
     </mrow> 
    </math> as the abscissa, to calculate and minimize the root-mean-square (rms)error.</p>
   <p>The t = 0 point in Equation (15) sets 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         N 
       </mi> 
       <mi>
         o 
       </mi> 
      </msub> 
     </mrow> 
    </math>. To best model Mitigation Measures, this point was usually chosen at the start of a downward curvature on a log-plot, so that 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        N 
      </mi> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mrow> 
        <mi>
          t 
        </mi> 
        <mo>
          = 
        </mo> 
        <mn>
          0 
        </mn> 
       </mrow> 
       <mo>
         ) 
       </mo> 
      </mrow> 
      <mo>
        ≡ 
      </mo> 
      <msub> 
       <mi>
         N 
       </mi> 
       <mi>
         I 
       </mi> 
      </msub> 
     </mrow> 
    </math>, where the 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         N 
       </mi> 
       <mi>
         I 
       </mi> 
      </msub> 
     </mrow> 
    </math> is now the first data point in the analysis. The prior 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        t 
      </mi> 
      <mo>
        &lt; 
      </mo> 
      <mn>
        0 
      </mn> 
     </mrow> 
    </math> regime can often have nearly pure exponential growth, as in <xref ref-type="fig" rid="fig2">
     Figure 2
    </xref>, and those regions should not be part of rms-error minimization for evaluating Mitigation Measures.</p>
   <p>The 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         N 
       </mi> 
       <mi>
         F 
       </mi> 
      </msub> 
     </mrow> 
    </math> final data point, measured at the most recent 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        t 
      </mi> 
      <mo>
        = 
      </mo> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mi>
         F 
       </mi> 
      </msub> 
     </mrow> 
    </math> time:</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        N 
      </mi> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mrow> 
        <mi>
          t 
        </mi> 
        <mo>
          = 
        </mo> 
        <msub> 
         <mi>
           t 
         </mi> 
         <mi>
           F 
         </mi> 
        </msub> 
       </mrow> 
       <mo>
         ) 
       </mo> 
      </mrow> 
      <mo>
        ≡ 
      </mo> 
      <msub> 
       <mi>
         N 
       </mi> 
       <mi>
         F 
       </mi> 
      </msub> 
     </mrow> 
    </math>. (16)</p>
   <p>was also fixed for each dataset, so that only { 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msub> 
      <mo>
        , 
      </mo> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math>} value pairs that meet both 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        N 
      </mi> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mrow> 
        <mi>
          t 
        </mi> 
        <mo>
          = 
        </mo> 
        <mn>
          0 
        </mn> 
       </mrow> 
       <mo>
         ) 
       </mo> 
      </mrow> 
      <mo>
        ≡ 
      </mo> 
      <msub> 
       <mi>
         N 
       </mi> 
       <mi>
         I 
       </mi> 
      </msub> 
     </mrow> 
    </math> and Equation (16) were used.</p>
   <p>In practice, an 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math> was chosen first. The Excel<sup>TM</sup>_Tools_Goal-Seek function was used to adjust 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msub> 
     </mrow> 
    </math> to obey Equation (16), setting the rms-error between the dataset and Equation (15), with the final { 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msub> 
      <mo>
        , 
      </mo> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math>} having the least rms-error.</p>
   <p>In the following figures, all CoVID-19 raw data came from the publicly available Microsoft “COVID-19 Tracker” site <xref ref-type="bibr" rid="scirp.143046-5">
     [5]
    </xref>. When no updates were available, that site repeated the prior day data, whereas we used the geometric mean of the day-prior and day-after data for interpolation.</p>
  </sec><sec id="s4">
   <title>
    <xref ref-type="bibr" rid="scirp.143046-"></xref>4. Effects of Varying the Initial Zero-Time Point</title>
   <p>Starting with:</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        N 
      </mi> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mi>
         t 
       </mi> 
       <mo>
         ) 
       </mo> 
      </mrow> 
      <mo>
        = 
      </mo> 
      <mn>
        1 
      </mn> 
      <mi>
        exp 
      </mi> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mo>
          + 
        </mo> 
        <mrow> 
         <mrow> 
          <msub> 
           <mi>
             K 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
          <mi>
            t 
          </mi> 
         </mrow> 
         <mo>
           / 
         </mo> 
         <mrow> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mrow> 
            <mn>
              1 
            </mn> 
            <mo>
              + 
            </mo> 
            <msub> 
             <mi>
               α 
             </mi> 
             <mi>
               S 
             </mi> 
            </msub> 
            <mi>
              t 
            </mi> 
           </mrow> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
        </mrow> 
        <mo>
          + 
        </mo> 
        <mi>
          ln 
        </mi> 
        <mrow> 
         <mo>
           ( 
         </mo> 
         <mrow> 
          <msub> 
           <mi>
             N 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
         </mrow> 
         <mo>
           ) 
         </mo> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
     </mrow> 
    </math>, (17)</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <munder> 
       <mrow> 
        <mi>
          lim 
        </mi> 
       </mrow> 
       <mrow> 
        <mi>
          t 
        </mi> 
        <mo>
          → 
        </mo> 
        <mo>
          + 
        </mo> 
        <mi>
          ∞ 
        </mi> 
       </mrow> 
      </munder> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mi>
          N 
        </mi> 
        <mrow> 
         <mo>
           ( 
         </mo> 
         <mi>
           t 
         </mi> 
         <mo>
           ) 
         </mo> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
      <mo>
        = 
      </mo> 
      <mn>
        1 
      </mn> 
      <mi>
        exp 
      </mi> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mo>
          + 
        </mo> 
        <mrow> 
         <mo>
           ( 
         </mo> 
         <mrow> 
          <mrow> 
           <mrow> 
            <msub> 
             <mi>
               K 
             </mi> 
             <mi>
               o 
             </mi> 
            </msub> 
           </mrow> 
           <mo>
             / 
           </mo> 
           <mrow> 
            <msub> 
             <mi>
               α 
             </mi> 
             <mi>
               S 
             </mi> 
            </msub> 
           </mrow> 
          </mrow> 
         </mrow> 
         <mo>
           ) 
         </mo> 
        </mrow> 
        <mo>
          + 
        </mo> 
        <mi>
          ln 
        </mi> 
        <mrow> 
         <mo>
           ( 
         </mo> 
         <mrow> 
          <msub> 
           <mi>
             N 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
         </mrow> 
         <mo>
           ) 
         </mo> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
     </mrow> 
    </math>, (18)</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msubsup> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
       <mi>
         o 
       </mi> 
      </msubsup> 
      <mo>
        ≡ 
      </mo> 
      <mrow> 
       <mrow> 
        <mrow> 
         <mo>
           ( 
         </mo> 
         <mrow> 
          <mi>
            ln 
          </mi> 
          <mn>
            2 
          </mn> 
         </mrow> 
         <mo>
           ) 
         </mo> 
        </mrow> 
       </mrow> 
       <mo>
         / 
       </mo> 
       <mrow> 
        <msub> 
         <mi>
           K 
         </mi> 
         <mi>
           o 
         </mi> 
        </msub> 
       </mrow> 
      </mrow> 
     </mrow> 
    </math>, (19)</p>
   <p>using a shifted time-scale normalization point is examined next:</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         N 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <msup> 
        <mi>
          t 
        </mi> 
        <mo>
          ′ 
        </mo> 
       </msup> 
       <mo>
         ) 
       </mo> 
      </mrow> 
      <mo>
        = 
      </mo> 
      <mn>
        1 
      </mn> 
      <mi>
        exp 
      </mi> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mo>
          + 
        </mo> 
        <mrow> 
         <mrow> 
          <msub> 
           <mi>
             K 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mrow> 
            <msup> 
             <mi>
               t 
             </mi> 
             <mo>
               ′ 
             </mo> 
            </msup> 
            <mo>
              + 
            </mo> 
            <msub> 
             <mi>
               t 
             </mi> 
             <mi>
               A 
             </mi> 
            </msub> 
           </mrow> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
         <mo>
           / 
         </mo> 
         <mrow> 
          <mrow> 
           <mo>
             [ 
           </mo> 
           <mrow> 
            <mn>
              1 
            </mn> 
            <mo>
              + 
            </mo> 
            <msub> 
             <mi>
               α 
             </mi> 
             <mi>
               S 
             </mi> 
            </msub> 
            <mrow> 
             <mo>
               ( 
             </mo> 
             <mrow> 
              <msup> 
               <mi>
                 t 
               </mi> 
               <mo>
                 ′ 
               </mo> 
              </msup> 
              <mo>
                + 
              </mo> 
              <msub> 
               <mi>
                 t 
               </mi> 
               <mi>
                 A 
               </mi> 
              </msub> 
             </mrow> 
             <mo>
               ) 
             </mo> 
            </mrow> 
           </mrow> 
           <mo>
             ] 
           </mo> 
          </mrow> 
         </mrow> 
        </mrow> 
        <mo>
          + 
        </mo> 
        <mi>
          ln 
        </mi> 
        <mrow> 
         <mo>
           ( 
         </mo> 
         <mrow> 
          <msub> 
           <mi>
             N 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
         </mrow> 
         <mo>
           ) 
         </mo> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
     </mrow> 
    </math>, (20)</p>
   <p>This 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         N 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <msup> 
        <mi>
          t 
        </mi> 
        <mo>
          ′ 
        </mo> 
       </msup> 
       <mo>
         ) 
       </mo> 
      </mrow> 
     </mrow> 
    </math> function should closely match Equation (17) with a shifted time axis: 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        t 
      </mi> 
      <mo>
        = 
      </mo> 
      <msup> 
       <mi>
         t 
       </mi> 
       <mo>
         ′ 
       </mo> 
      </msup> 
      <mo>
        + 
      </mo> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mi>
         A 
       </mi> 
      </msub> 
     </mrow> 
    </math>, but the best fit parameter numerical values change. Since:</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mn>
          1 
        </mn> 
        <mo>
          + 
        </mo> 
        <msub> 
         <mi>
           α 
         </mi> 
         <mi>
           S 
         </mi> 
        </msub> 
        <mrow> 
         <mo>
           ( 
         </mo> 
         <mrow> 
          <msup> 
           <mi>
             t 
           </mi> 
           <mo>
             ′ 
           </mo> 
          </msup> 
          <mo>
            + 
          </mo> 
          <msub> 
           <mi>
             t 
           </mi> 
           <mi>
             A 
           </mi> 
          </msub> 
         </mrow> 
         <mo>
           ) 
         </mo> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
      <mo>
        = 
      </mo> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mn>
          1 
        </mn> 
        <mo>
          + 
        </mo> 
        <msub> 
         <mi>
           α 
         </mi> 
         <mi>
           S 
         </mi> 
        </msub> 
        <msub> 
         <mi>
           t 
         </mi> 
         <mi>
           A 
         </mi> 
        </msub> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mn>
          1 
        </mn> 
        <mo>
          + 
        </mo> 
        <mfrac> 
         <mrow> 
          <msub> 
           <mi>
             α 
           </mi> 
           <mi>
             S 
           </mi> 
          </msub> 
          <msup> 
           <mi>
             t 
           </mi> 
           <mo>
             ′ 
           </mo> 
          </msup> 
         </mrow> 
         <mrow> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mrow> 
            <mn>
              1 
            </mn> 
            <mo>
              + 
            </mo> 
            <msub> 
             <mi>
               α 
             </mi> 
             <mi>
               S 
             </mi> 
            </msub> 
            <msub> 
             <mi>
               t 
             </mi> 
             <mi>
               A 
             </mi> 
            </msub> 
           </mrow> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
        </mfrac> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
     </mrow> 
    </math>, (21)</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mfrac> 
       <mrow> 
        <msub> 
         <mi>
           K 
         </mi> 
         <mi>
           o 
         </mi> 
        </msub> 
        <mrow> 
         <mo>
           ( 
         </mo> 
         <mrow> 
          <msup> 
           <mi>
             t 
           </mi> 
           <mo>
             ′ 
           </mo> 
          </msup> 
          <mo>
            + 
          </mo> 
          <msub> 
           <mi>
             t 
           </mi> 
           <mi>
             A 
           </mi> 
          </msub> 
         </mrow> 
         <mo>
           ) 
         </mo> 
        </mrow> 
       </mrow> 
       <mrow> 
        <mrow> 
         <mo>
           [ 
         </mo> 
         <mrow> 
          <mn>
            1 
          </mn> 
          <mo>
            + 
          </mo> 
          <msub> 
           <mi>
             α 
           </mi> 
           <mi>
             S 
           </mi> 
          </msub> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mrow> 
            <msup> 
             <mi>
               t 
             </mi> 
             <mo>
               ′ 
             </mo> 
            </msup> 
            <mo>
              + 
            </mo> 
            <msub> 
             <mi>
               t 
             </mi> 
             <mi>
               A 
             </mi> 
            </msub> 
           </mrow> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
         <mo>
           ] 
         </mo> 
        </mrow> 
       </mrow> 
      </mfrac> 
      <mo>
        = 
      </mo> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mn>
          1 
        </mn> 
        <mo>
          + 
        </mo> 
        <mfrac> 
         <mrow> 
          <msub> 
           <mi>
             t 
           </mi> 
           <mi>
             A 
           </mi> 
          </msub> 
         </mrow> 
         <msup> 
          <mi>
            t 
          </mi> 
          <mo>
            ′ 
          </mo> 
         </msup> 
        </mfrac> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
      <mrow> 
       <mrow> 
        <mfrac> 
         <mrow> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mrow> 
            <msub> 
             <mi>
               K 
             </mi> 
             <mi>
               o 
             </mi> 
            </msub> 
            <msup> 
             <mi>
               t 
             </mi> 
             <mo>
               ′ 
             </mo> 
            </msup> 
           </mrow> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
         <mrow> 
          <mrow> 
           <mo>
             [ 
           </mo> 
           <mrow> 
            <mn>
              1 
            </mn> 
            <mo>
              + 
            </mo> 
            <msub> 
             <mi>
               α 
             </mi> 
             <mi>
               S 
             </mi> 
            </msub> 
            <msub> 
             <mi>
               t 
             </mi> 
             <mi>
               A 
             </mi> 
            </msub> 
           </mrow> 
           <mo>
             ] 
           </mo> 
          </mrow> 
         </mrow> 
        </mfrac> 
       </mrow> 
       <mo>
         / 
       </mo> 
       <mrow> 
        <mrow> 
         <mo>
           [ 
         </mo> 
         <mrow> 
          <mn>
            1 
          </mn> 
          <mo>
            + 
          </mo> 
          <mfrac> 
           <mrow> 
            <msub> 
             <mi>
               α 
             </mi> 
             <mi>
               S 
             </mi> 
            </msub> 
            <msup> 
             <mi>
               t 
             </mi> 
             <mo>
               ′ 
             </mo> 
            </msup> 
           </mrow> 
           <mrow> 
            <mrow> 
             <mo>
               ( 
             </mo> 
             <mrow> 
              <mn>
                1 
              </mn> 
              <mo>
                + 
              </mo> 
              <msub> 
               <mi>
                 α 
               </mi> 
               <mi>
                 S 
               </mi> 
              </msub> 
              <msub> 
               <mi>
                 t 
               </mi> 
               <mi>
                 A 
               </mi> 
              </msub> 
             </mrow> 
             <mo>
               ) 
             </mo> 
            </mrow> 
           </mrow> 
          </mfrac> 
         </mrow> 
         <mo>
           ] 
         </mo> 
        </mrow> 
       </mrow> 
      </mrow> 
     </mrow> 
    </math>, (22)</p>
   <p>then defining:</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         A 
       </mi> 
      </msub> 
      <mo>
        ≡ 
      </mo> 
      <mrow> 
       <mrow> 
        <msub> 
         <mi>
           α 
         </mi> 
         <mi>
           S 
         </mi> 
        </msub> 
       </mrow> 
       <mo>
         / 
       </mo> 
       <mrow> 
        <mrow> 
         <mo>
           ( 
         </mo> 
         <mrow> 
          <mn>
            1 
          </mn> 
          <mo>
            + 
          </mo> 
          <msub> 
           <mi>
             α 
           </mi> 
           <mi>
             S 
           </mi> 
          </msub> 
          <msub> 
           <mi>
             t 
           </mi> 
           <mi>
             A 
           </mi> 
          </msub> 
         </mrow> 
         <mo>
           ) 
         </mo> 
        </mrow> 
       </mrow> 
      </mrow> 
     </mrow> 
    </math>, (23)</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         K 
       </mi> 
       <mi>
         A 
       </mi> 
      </msub> 
      <mo>
        ≡ 
      </mo> 
      <mrow> 
       <mrow> 
        <msub> 
         <mi>
           K 
         </mi> 
         <mi>
           o 
         </mi> 
        </msub> 
       </mrow> 
       <mo>
         / 
       </mo> 
       <mrow> 
        <mrow> 
         <mo>
           ( 
         </mo> 
         <mrow> 
          <mn>
            1 
          </mn> 
          <mo>
            + 
          </mo> 
          <msub> 
           <mi>
             α 
           </mi> 
           <mi>
             S 
           </mi> 
          </msub> 
          <msub> 
           <mi>
             t 
           </mi> 
           <mi>
             A 
           </mi> 
          </msub> 
         </mrow> 
         <mo>
           ) 
         </mo> 
        </mrow> 
       </mrow> 
      </mrow> 
     </mrow> 
    </math>, (24)</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msubsup> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
       <mi>
         A 
       </mi> 
      </msubsup> 
      <mo>
        ≡ 
      </mo> 
      <mrow> 
       <mrow> 
        <mrow> 
         <mo>
           ( 
         </mo> 
         <mrow> 
          <mi>
            ln 
          </mi> 
          <mn>
            2 
          </mn> 
         </mrow> 
         <mo>
           ) 
         </mo> 
        </mrow> 
       </mrow> 
       <mo>
         / 
       </mo> 
       <mrow> 
        <msub> 
         <mi>
           K 
         </mi> 
         <mi>
           A 
         </mi> 
        </msub> 
       </mrow> 
      </mrow> 
      <mo>
        = 
      </mo> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mrow> 
        <mn>
          1 
        </mn> 
        <mo>
          + 
        </mo> 
        <msub> 
         <mi>
           α 
         </mi> 
         <mi>
           S 
         </mi> 
        </msub> 
        <msub> 
         <mi>
           t 
         </mi> 
         <mi>
           A 
         </mi> 
        </msub> 
       </mrow> 
       <mo>
         ) 
       </mo> 
      </mrow> 
      <msubsup> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
       <mi>
         o 
       </mi> 
      </msubsup> 
      <mo>
        = 
      </mo> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mrow> 
        <mn>
          1 
        </mn> 
        <mo>
          + 
        </mo> 
        <msub> 
         <mi>
           α 
         </mi> 
         <mi>
           S 
         </mi> 
        </msub> 
        <msub> 
         <mi>
           t 
         </mi> 
         <mi>
           A 
         </mi> 
        </msub> 
       </mrow> 
       <mo>
         ) 
       </mo> 
      </mrow> 
      <mrow> 
       <mrow> 
        <mrow> 
         <mo>
           ( 
         </mo> 
         <mrow> 
          <mi>
            ln 
          </mi> 
          <mn>
            2 
          </mn> 
         </mrow> 
         <mo>
           ) 
         </mo> 
        </mrow> 
       </mrow> 
       <mo>
         / 
       </mo> 
       <mrow> 
        <msub> 
         <mi>
           K 
         </mi> 
         <mi>
           o 
         </mi> 
        </msub> 
       </mrow> 
      </mrow> 
     </mrow> 
    </math>, (25)</p>
   <p>it gives:</p>
   <p>
    <math display="inline" xmlns="http://www.w3.org/1998/Math/MathML"> <mtable> 
      <mtr> 
       <mtd> 
        <mfrac> 
         <mrow> 
          <msub> 
           <mi>
             K 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mrow> 
            <msup> 
             <mi>
               t 
             </mi> 
             <mo>
               ′ 
             </mo> 
            </msup> 
            <mo>
              + 
            </mo> 
            <msub> 
             <mi>
               t 
             </mi> 
             <mi>
               A 
             </mi> 
            </msub> 
           </mrow> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
         <mrow> 
          <mrow> 
           <mo>
             [ 
           </mo> 
           <mrow> 
            <mn>
              1 
            </mn> 
            <mo>
              + 
            </mo> 
            <msub> 
             <mi>
               α 
             </mi> 
             <mi>
               S 
             </mi> 
            </msub> 
            <mrow> 
             <mo>
               ( 
             </mo> 
             <mrow> 
              <msup> 
               <mi>
                 t 
               </mi> 
               <mo>
                 ′ 
               </mo> 
              </msup> 
              <mo>
                + 
              </mo> 
              <msub> 
               <mi>
                 t 
               </mi> 
               <mi>
                 A 
               </mi> 
              </msub> 
             </mrow> 
             <mo>
               ) 
             </mo> 
            </mrow> 
           </mrow> 
           <mo>
             ] 
           </mo> 
          </mrow> 
         </mrow> 
        </mfrac> 
        <mo>
          = 
        </mo> 
        <mrow> 
         <mrow> 
          <mrow> 
           <mo>
             [ 
           </mo> 
           <mrow> 
            <mn>
              1 
            </mn> 
            <mo>
              + 
            </mo> 
            <mfrac> 
             <mrow> 
              <msub> 
               <mi>
                 t 
               </mi> 
               <mi>
                 A 
               </mi> 
              </msub> 
             </mrow> 
             <msup> 
              <mi>
                t 
              </mi> 
              <mo>
                ′ 
              </mo> 
             </msup> 
            </mfrac> 
           </mrow> 
           <mo>
             ] 
           </mo> 
          </mrow> 
          <msub> 
           <mi>
             K 
           </mi> 
           <mi>
             A 
           </mi> 
          </msub> 
          <msup> 
           <mi>
             t 
           </mi> 
           <mo>
             ′ 
           </mo> 
          </msup> 
         </mrow> 
         <mo>
           / 
         </mo> 
         <mrow> 
          <mrow> 
           <mo>
             [ 
           </mo> 
           <mrow> 
            <mn>
              1 
            </mn> 
            <mo>
              + 
            </mo> 
            <msub> 
             <mi>
               α 
             </mi> 
             <mi>
               A 
             </mi> 
            </msub> 
            <msup> 
             <mi>
               t 
             </mi> 
             <mo>
               ′ 
             </mo> 
            </msup> 
           </mrow> 
           <mo>
             ] 
           </mo> 
          </mrow> 
         </mrow> 
        </mrow> 
       </mtd> 
      </mtr> 
      <mtr> 
       <mtd> 
        <mo>
          = 
        </mo> 
        <mrow> 
         <mrow> 
          <msub> 
           <mi>
             K 
           </mi> 
           <mi>
             A 
           </mi> 
          </msub> 
          <msup> 
           <mi>
             t 
           </mi> 
           <mo>
             ′ 
           </mo> 
          </msup> 
         </mrow> 
         <mo>
           / 
         </mo> 
         <mrow> 
          <mrow> 
           <mo>
             [ 
           </mo> 
           <mrow> 
            <mn>
              1 
            </mn> 
            <mo>
              + 
            </mo> 
            <msub> 
             <mi>
               α 
             </mi> 
             <mi>
               A 
             </mi> 
            </msub> 
            <msup> 
             <mi>
               t 
             </mi> 
             <mo>
               ′ 
             </mo> 
            </msup> 
           </mrow> 
           <mo>
             ] 
           </mo> 
          </mrow> 
         </mrow> 
        </mrow> 
        <mo>
          + 
        </mo> 
        <mrow> 
         <mrow> 
          <msub> 
           <mi>
             K 
           </mi> 
           <mi>
             A 
           </mi> 
          </msub> 
          <msub> 
           <mi>
             t 
           </mi> 
           <mi>
             A 
           </mi> 
          </msub> 
         </mrow> 
         <mo>
           / 
         </mo> 
         <mrow> 
          <mrow> 
           <mo>
             [ 
           </mo> 
           <mrow> 
            <mn>
              1 
            </mn> 
            <mo>
              + 
            </mo> 
            <msub> 
             <mi>
               α 
             </mi> 
             <mi>
               A 
             </mi> 
            </msub> 
            <msup> 
             <mi>
               t 
             </mi> 
             <mo>
               ′ 
             </mo> 
            </msup> 
           </mrow> 
           <mo>
             ] 
           </mo> 
          </mrow> 
         </mrow> 
        </mrow> 
       </mtd> 
      </mtr> 
     </mtable> 
    </math>. (26)</p>
   <p>These equations highlight the net effect of time-shifting. For 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mi>
         A 
       </mi> 
      </msub> 
      <mo>
        &gt; 
      </mo> 
      <mn>
        0 
      </mn> 
     </mrow> 
    </math>, when 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <msup> 
      <mi>
        t 
      </mi> 
      <mo>
        ′ 
      </mo> 
     </msup> 
    </math> begins after Mitigation Measures have started, the shifted-time-axis results in a larger calculated doubling-time and a smaller SMP 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         A 
       </mi> 
      </msub> 
     </mrow> 
    </math>-value. For 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mi>
         A 
       </mi> 
      </msub> 
      <mo>
        &lt; 
      </mo> 
      <mn>
        0 
      </mn> 
     </mrow> 
    </math>, when 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <msup> 
      <mi>
        t 
      </mi> 
      <mo>
        ′ 
      </mo> 
     </msup> 
    </math> may include Mitigation Measures already in place at the Equations (17)-(19) 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        t 
      </mi> 
      <mo>
        = 
      </mo> 
      <mn>
        0 
      </mn> 
     </mrow> 
    </math> point, this shifted-time-axis results in a smaller calculated doubling-time and a larger SMP 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         A 
       </mi> 
      </msub> 
     </mrow> 
    </math>-value.</p>
   <p>Finally, for small 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <msup> 
      <mi>
        t 
      </mi> 
      <mo>
        ′ 
      </mo> 
     </msup> 
    </math>, where 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         A 
       </mi> 
      </msub> 
      <msup> 
       <mi>
         t 
       </mi> 
       <mo>
         ′ 
       </mo> 
      </msup> 
      <mo>
        &lt; 
      </mo> 
      <mn>
        1 
      </mn> 
     </mrow> 
    </math>, using Equations (18) and (26) gives:</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mn>
        1 
      </mn> 
      <mi>
        exp 
      </mi> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mfrac> 
         <mrow> 
          <mo>
            + 
          </mo> 
          <msub> 
           <mi>
             K 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
          <mi>
            t 
          </mi> 
         </mrow> 
         <mrow> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mrow> 
            <mn>
              1 
            </mn> 
            <mo>
              + 
            </mo> 
            <msub> 
             <mi>
               α 
             </mi> 
             <mi>
               S 
             </mi> 
            </msub> 
            <mi>
              t 
            </mi> 
           </mrow> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
        </mfrac> 
        <mo>
          + 
        </mo> 
        <mi>
          ln 
        </mi> 
        <mrow> 
         <mo>
           ( 
         </mo> 
         <mrow> 
          <msub> 
           <mi>
             N 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
         </mrow> 
         <mo>
           ) 
         </mo> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
      <mo>
        ≈ 
      </mo> 
      <mn>
        1 
      </mn> 
      <mi>
        exp 
      </mi> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mfrac> 
         <mrow> 
          <mo>
            + 
          </mo> 
          <msub> 
           <mi>
             K 
           </mi> 
           <mi>
             A 
           </mi> 
          </msub> 
          <msup> 
           <mi>
             t 
           </mi> 
           <mo>
             ′ 
           </mo> 
          </msup> 
         </mrow> 
         <mrow> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mrow> 
            <mn>
              1 
            </mn> 
            <mo>
              + 
            </mo> 
            <msub> 
             <mi>
               α 
             </mi> 
             <mi>
               A 
             </mi> 
            </msub> 
            <msup> 
             <mi>
               t 
             </mi> 
             <mo>
               ′ 
             </mo> 
            </msup> 
           </mrow> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
        </mfrac> 
        <mo>
          + 
        </mo> 
        <mi>
          ln 
        </mi> 
        <mrow> 
         <mo>
           ( 
         </mo> 
         <mrow> 
          <msub> 
           <mi>
             N 
           </mi> 
           <mi>
             A 
           </mi> 
          </msub> 
         </mrow> 
         <mo>
           ) 
         </mo> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
     </mrow> 
    </math>, (27)</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
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     </mrow> 
    </math>, (28)</p>
   <p>which shows that the 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msup> 
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         ′ 
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        = 
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    </math> new initial state should have an 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         N 
       </mi> 
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         A 
       </mi> 
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     </mrow> 
    </math> starting value obeying 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         N 
       </mi> 
       <mi>
         A 
       </mi> 
      </msub> 
      <mo>
        &gt; 
      </mo> 
      <msub> 
       <mi>
         N 
       </mi> 
       <mi>
         o 
       </mi> 
      </msub> 
     </mrow> 
    </math> for 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mi>
         A 
       </mi> 
      </msub> 
      <mo>
        &gt; 
      </mo> 
      <mn>
        0 
      </mn> 
     </mrow> 
    </math>, and 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         N 
       </mi> 
       <mi>
         A 
       </mi> 
      </msub> 
      <mo>
        &lt; 
      </mo> 
      <msub> 
       <mi>
         N 
       </mi> 
       <mi>
         o 
       </mi> 
      </msub> 
     </mrow> 
    </math> for 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
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       </mi> 
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       </mi> 
      </msub> 
      <mo>
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      </mo> 
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        0 
      </mn> 
     </mrow> 
    </math>. However, whether { 
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      <msub> 
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       </mi> 
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        , 
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         K 
       </mi> 
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         o 
       </mi> 
      </msub> 
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        , 
      </mo> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math>}, or an alternative { 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         N 
       </mi> 
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         A 
       </mi> 
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      <mo>
        , 
      </mo> 
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        , 
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     </mrow> 
    </math>}, are used to parameterize a given data set, the net overall function fit and predictions, as a function of calendar date, should remain fairly self-consistent, even when some ambiguity exists as to when Mitigation Measures first were noticeably effective.</p>
  </sec><sec id="s5">
   <title>
    <xref ref-type="bibr" rid="scirp.143046-"></xref>5. USA and Selected States Model Results</title>
   <p>The model predictions for CoVID-19 spread in the USA is shown in <xref ref-type="fig" rid="fig3">
     Figure 3
    </xref>. This analysis only included data after mid-March 2020, when several State Governors first instituted mandatory Mitigation Measures. Results give an SMP estimate of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math> ≈ 0.05945/day, a USA initial doubling-time of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msubsup> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
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        </mi> 
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        </mi> 
        <mi>
          l 
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       </mrow> 
       <mrow> 
        <mi>
          i 
        </mi> 
        <mi>
          n 
        </mi> 
        <mi>
          i 
        </mi> 
        <mi>
          t 
        </mi> 
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        </mi> 
        <mi>
          a 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msubsup> 
     </mrow> 
    </math> ≈ 2.1758 days, which lengthens to 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msubsup> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
       <mrow> 
        <mrow> 
         <mo>
           { 
         </mo> 
         <mrow> 
          <mtext>
            at Peak 
          </mtext> 
         </mrow> 
         <mo>
           } 
         </mo> 
        </mrow> 
       </mrow> 
      </msubsup> 
     </mrow> 
    </math> ≈ 5.83 days at the projected pandemic peak of 4/19/2020. The predicted total number of CoVID-19 cases is 5,464,000, giving a projected 1.67% final infection rate, if the present level of Mitigation Measures or their equivalent, are continued.</p>
   <p>These predictions assume no “second wave” of infection or re-infection. They also do not include the effect of additional Mitigation Measures, which could further increase the { 
    <math display="inline" xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
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          d 
        </mi> 
        <mi>
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        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msub> 
      <mo>
        , 
      </mo> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math>} values, and significantly reduce the projected final number of CoVID-19 cases.</p>
   <p>
    <xref ref-type="fig" rid="fig4">
     Figure 4
    </xref> shows model predictions for CoVID-19 evolution in California. Only data after 3/21/2020 was included in the analysis, after California Governor Gavin Newsom instituted mandatory Mitigation Measures. It gives an SMP estimate of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math> ≈ 0.03546/day, with an initial doubling-time of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msubsup> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
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        <mi>
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        <mi>
          l 
        </mi> 
       </mrow> 
       <mrow> 
        <mi>
          i 
        </mi> 
        <mi>
          n 
        </mi> 
        <mi>
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        </mi> 
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        </mi> 
        <mi>
          a 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msubsup> 
     </mrow> 
    </math> ≈ 2.5017 days, which lengthens to 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msubsup> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
       <mrow> 
        <mrow> 
         <mo>
           { 
         </mo> 
         <mrow> 
          <mtext>
            at Peak 
          </mtext> 
         </mrow> 
         <mo>
           } 
         </mo> 
        </mrow> 
       </mrow> 
      </msubsup> 
     </mrow> 
    </math> ≈ 9.774 days at the projected pandemic peak of 6/07/2020. The predicted total number of CoVID-19 cases is 1,123,700, giving a projected 2.813% final infection rate, at the present level of Mitigation Measures.</p>
   <p>
    <xref ref-type="fig" rid="fig5">
     Figure 5
    </xref> shows model predictions for CoVID-19 evolution in New York. A relatively high SMP estimate of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math> ≈ 0.1031/day was found, coupled with a relatively short initial doubling-time of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msubsup> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
       <mrow> 
        <mi>
          i 
        </mi> 
        <mi>
          n 
        </mi> 
        <mi>
          i 
        </mi> 
        <mi>
          t 
        </mi> 
        <mi>
          i 
        </mi> 
        <mi>
          a 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msubsup> 
     </mrow> 
    </math> ≈ 0.9395 days, which creates a high narrow spike in daily new cases. The present model projects a New York pandemic peak around 4/10/2020, with an estimated at-peak doubling-time of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msubsup> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
       <mrow> 
        <mrow> 
         <mo>
           { 
         </mo> 
         <mrow> 
          <mtext>
            at Peak 
          </mtext> 
         </mrow> 
         <mo>
           } 
         </mo> 
        </mrow> 
       </mrow> 
      </msubsup> 
     </mrow> 
    </math> ≈ 3.36 days. The predicted total number of cases is 1,218,000, giving a projected 6.072% final infection rate.</p>
   <p>
    <xref ref-type="fig" rid="fig6">
     Figure 6
    </xref> shows model predictions for CoVID-19 evolution in Washington State. An initial doubling-time of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msubsup> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
       <mrow> 
        <mi>
          i 
        </mi> 
        <mi>
          n 
        </mi> 
        <mi>
          i 
        </mi> 
        <mi>
          t 
        </mi> 
        <mi>
          i 
        </mi> 
        <mi>
          a 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msubsup> 
     </mrow> 
    </math> ≈ 2.2005 days and an SMP value of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math> ≈ 0.0366/day were found, with a projected pandemic peak around 6/04/2020. The relatively low number of cases at the Mitigation Measures start helps to give a predicted total number of cases of 557,600, corresponding to a 7.15% final infection rate.</p>
   <fig id="fig3" position="float">
    <label>Figure 3</label>
    <caption>
     <title>Figure 3. USA Model Predictions. To allow better mitigation predictions, only data after mid-March 2020 was included, when several Governors instituted mandatory lockdowns.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2313106-rId311.jpeg?20250603091018" />
   </fig>
   <fig id="fig4" position="float">
    <label>Figure 4</label>
    <caption>
     <title>Figure 4. Predicted California CoVID-19 results. After Gov. Gavin Newsom instituted widespread Mitigation Measures, projections showed significant improvement.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2313106-rId312.jpeg?20250603091018" />
   </fig>
   <fig id="fig5" position="float">
    <label>Figure 5</label>
    <caption>
     <title>Figure 5. Predicted New York CoVID-19 results. A relatively high Mitigation Measure level and a short intrinsic doubling time creates a narrow spike in daily new cases.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2313106-rId313.jpeg?20250603091019" />
   </fig>
   <fig id="fig6" position="float">
    <label>Figure 6</label>
    <caption>
     <title>Figure 6. Predicted Washington State CoVID-19 results. The relatively low number of cases at Mitigation Measure start helps to give a relatively low final number of cases.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2313106-rId314.jpeg?20250603091019" />
   </fig>
   <fig id="fig7" position="float">
    <label>Figure 7</label>
    <caption>
     <title>Figure 7. Predicted Illinois CoVID-19 results. The slow doubling-time and moderate amount of Mitigation Measures gives a slow increase to the predicted CoVID-19 peak.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2313106-rId315.jpeg?20250603091019" />
   </fig>
   <fig id="fig8" position="float">
    <label>Figure 8</label>
    <caption>
     <title>Figure 8. Predicted Florida CoVID-19 results. Many Florida counties instituted their own Mitigation Measures prior to a state-wide lockdown, substantially slowing CoVID-19 growth.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2313106-rId316.jpeg?20250603091019" />
   </fig>
   <p>
    <xref ref-type="fig" rid="fig7">
     Figure 7
    </xref> shows model predictions for CoVID-19 evolution in Illinois. An initial doubling-time of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msubsup> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
       <mrow> 
        <mi>
          i 
        </mi> 
        <mi>
          n 
        </mi> 
        <mi>
          i 
        </mi> 
        <mi>
          t 
        </mi> 
        <mi>
          i 
        </mi> 
        <mi>
          a 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msubsup> 
     </mrow> 
    </math> ≈ 2.457 days and moderate SMP value of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math> ≈ 0.0373/day combine to give a projected pandemic peak around 6/04/2020, similar to Washington State, but having a higher predicted total number of cases at 1,277,000, and a projected 11.47% final infection rate.</p>
   <p>
    <xref ref-type="fig" rid="fig8">
     Figure 8
    </xref> shows model predictions for CoVID-19 evolution in Florida. Many Florida counties instituted their own Mitigation Measures prior to a state-wide lockdown, slowing CoVID-19 growth. A somewhat high SMP value of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math> ≈ 0.0526/day, and an initial doubling-time of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msubsup> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
       <mrow> 
        <mi>
          i 
        </mi> 
        <mi>
          n 
        </mi> 
        <mi>
          i 
        </mi> 
        <mi>
          t 
        </mi> 
        <mi>
          i 
        </mi> 
        <mi>
          a 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msubsup> 
     </mrow> 
    </math> ≈ 1.494 days results. A pandemic peak is estimated at around 5/20/2020, with a predicted total number of cases at 1,090,000, and a projected 4.96% final infection rate.</p>
  </sec><sec id="s6">
   <title>
    <xref ref-type="bibr" rid="scirp.143046-"></xref>6. World and Selected Countries Model Results</title>
   <p>
    <xref ref-type="fig" rid="fig9">
     Figure 9
    </xref> shows model predictions of CoVID-19 evolution for the whole World. The present-day doubling-time value of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msubsup> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
       <mrow> 
        <mi>
          i 
        </mi> 
        <mi>
          n 
        </mi> 
        <mi>
          i 
        </mi> 
        <mi>
          t 
        </mi> 
        <mi>
          i 
        </mi> 
        <mi>
          a 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msubsup> 
     </mrow> 
    </math> ≈ 5.761 days likely represents a combination of small urban, large urban, and rural area results. However, the calculated low SMP estimate of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math> ≈ 0.01712/day shows that nearly 4.43% of the World’s population could be at risk for eventual CoVID-19 infection. At these present levels, the projected pandemic peak is around 8/15/2020, with potentially hundreds of millions of people being infected.</p>
   <p>
    <xref ref-type="fig" rid="fig10">
     Figure 10
    </xref> shows model predictions for CoVID-19 evolution in China, covering their “first wave” of early exposure and early mitigation. Data were included that was prior to a “New Reporting Method” being used, which started off with one sudden data jump, and nearly level CoVID-19 follow-on results. The present model predicts what number of cases could have resulted, had the reporting method not changed. Draconian Mitigation Measures helped to contain the pandemic to Hubei Province and Wuhan. These projections show that those Mitigation Measures have impressively contained CoVID-19 spread.</p>
   <p>
    <xref ref-type="fig" rid="fig11">
     Figure 11
    </xref> shows model predictions for CoVID-19 evolution in South Korea, covering the period of their country’s early exposure and initial mitigation methods. Pre-pandemic Mitigation Measures, including extensive contact-tracing and large-scale CoVID-19 testing, were implemented. These projections show that those Mitigation Measures, as an alternative to China’s methods, also have impressively contained CoVID-19 spread.</p>
   <p>
    <xref ref-type="fig" rid="fig12">
     Figure 12
    </xref> shows model predictions for CoVID-19 evolution in Italy. An initial doubling-time of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msubsup> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
       <mrow> 
        <mi>
          i 
        </mi> 
        <mi>
          n 
        </mi> 
        <mi>
          i 
        </mi> 
        <mi>
          t 
        </mi> 
        <mi>
          i 
        </mi> 
        <mi>
          a 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msubsup> 
     </mrow> 
    </math> ≈ 1.4648 days and SMP estimate of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math> ≈ 0.05282/day give a pandemic peak around 4/29/2020, with a predicted number of total cases at 1,764,000 and a projected 2.92% final infection rate.</p>
   <p>
    <xref ref-type="fig" rid="fig13">
     Figure 13
    </xref> shows model predictions for CoVID-19 evolution in Germany. The relatively high SMP estimate of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math> ≈ 0.07614/day with an initial doubling-time of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msubsup> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
       <mrow> 
        <mi>
          i 
        </mi> 
        <mi>
          n 
        </mi> 
        <mi>
          i 
        </mi> 
        <mi>
          t 
        </mi> 
        <mi>
          i 
        </mi> 
        <mi>
          a 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msubsup> 
     </mrow> 
    </math> ≈ 1.4177 days combine to give a projected pandemic peak at around 4/08/2020, with a predicted total number of cases of 700,100 and a projected 0.84% final infection rate. These values would make Germany one of the countries with the least impact in Europe. They represent predicted final CoVID-19 infection rates that are significantly lower than the original 60% - 70% early worst-case estimates highlighted by German Chancellor Angela Merkel.</p>
   <p>
    <xref ref-type="fig" rid="fig14">
     Figure 14
    </xref> shows model predictions for CoVID-19 evolution in Spain. An SMP estimate of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math> ≈ 0.07058/day, which is comparable to Germany, and a smaller initial doubling-time of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msubsup> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
       <mrow> 
        <mi>
          i 
        </mi> 
        <mi>
          n 
        </mi> 
        <mi>
          i 
        </mi> 
        <mi>
          t 
        </mi> 
        <mi>
          i 
        </mi> 
        <mi>
          a 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msubsup> 
     </mrow> 
    </math> ≈ 1.1778 days combine to give more predicted CoVID-19 cases than Germany. The estimated pandemic peak is around 4/21/2020, with a predicted number of total cases at 1,526,000 and a projected 3.26% final infection rate.</p>
   <p>
    <xref ref-type="fig" rid="fig15">
     Figure 15
    </xref> shows model predictions for CoVID-19 evolution in Ecuador. Reports of chaos in Ecuador have been alarming. Yet the present data show a significant and somewhat unexpected leveling off in the number of reported CoVID-19 cases. This result could mean that some yet unknown Mitigation Measures may be operating. Alternatively, the data could mean that there is a dire CoVID-19 testing and reporting shortfall operating amidst chaos.</p>
   <p>
    <xref ref-type="fig" rid="fig16">
     Figure 16
    </xref> shows model predictions for CoVID-19 evolution in India. These initial data show virtually no mitigation at present, having one of the lowest calculated SMP estimates of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math> ≈ 0.0148/day, with an initial doubling-time of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msubsup> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
       <mrow> 
        <mi>
          i 
        </mi> 
        <mi>
          n 
        </mi> 
        <mi>
          i 
        </mi> 
        <mi>
          t 
        </mi> 
        <mi>
          i 
        </mi> 
        <mi>
          a 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msubsup> 
     </mrow> 
    </math> ≈ 3.135 days. At this rate, nearly 17.38% of the population of India could eventually become infected. The estimated pandemic peak is around 5/30/2021, which would be 441 days after the first CoVID-19 fatality was reported, on 3/14/2020. Additional Mitigation Measures, further increasing the { 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msub> 
      <mo>
        , 
      </mo> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math>} values, as well as using additional modeling parameters may significantly reduce these projected number of CoVID-19 cases.</p>
   <fig id="fig9" position="float">
    <label>Figure 9</label>
    <caption>
     <title>Figure 9. Model predictions for the WORLD, showing present-day low level of mitigation.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2313106-rId333.jpeg?20250603091020" />
   </fig>
   <fig id="fig10" position="float">
    <label>Figure 10</label>
    <caption>
     <title>Figure 10. Predicted CHINA CoVID-19 results, using pre-“New Reporting Method” data. Draconian Mitigation Measures helped to contain pandemic to Hubei Province and Wuhan.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2313106-rId334.jpeg?20250603091020" />
   </fig>
   <fig id="fig11" position="float">
    <label>Figure 11</label>
    <caption>
     <title>Figure 11. Predicted SOUTH KOREA CoVID-19 results. Pre-pandemic contact-tracing and large-scale CoVID-19 testing as Mitigation Measures have contained the pandemic.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2313106-rId335.jpeg?20250603091020" />
   </fig>
   <fig id="fig12" position="float">
    <label>Figure 12</label>
    <caption>
     <title>Figure 12. Predicted ITALY CoVID-19 results. Additional curvature in the actual CoVID-19 data vs Model makes these predictions a likely worst-case.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2313106-rId336.jpeg?20250603091020" />
   </fig>
   <fig id="fig13" position="float">
    <label>Figure 13</label>
    <caption>
     <title>Figure 13. Predicted GERMANY CoVID-19 results. This model gives a more gradual function for the Daily New CoVID-19 cases, making these predictions a likely worst-case.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2313106-rId337.jpeg?20250603091020" />
   </fig>
   <fig id="fig14" position="float">
    <label>Figure 14</label>
    <caption>
     <title>Figure 14. Predicted SPAIN CoVID-19 results. This model gives a more gradual function for Daily New CoVID-19 cases, making these predictions a likely worst-case.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2313106-rId338.jpeg?20250603091021" />
   </fig>
   <fig id="fig15" position="float">
    <label>Figure 15</label>
    <caption>
     <title>Figure 15. Predicted ECUADOR CoVID-19 results. Reports of chaos in Ecuador have been alarming. Poor CoVID-19 tracking and low testing may have skewed these results.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2313106-rId339.jpeg?20250603091020" />
   </fig>
   <fig id="fig16" position="float">
    <label>Figure 16</label>
    <caption>
     <title>Figure 16. Predicted INDIA CoVID-19 results. Data shows only minimal mitigation at present. Further mitigations should help make these predictions a worst-case result.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2313106-rId340.jpeg?20250603091021" />
   </fig>
  </sec><sec id="s7">
   <title>
    <xref ref-type="bibr" rid="scirp.143046-"></xref>7. Augmented Peak Shape Modeling</title>
   <p>Using a new Social Mitigation Parameter [SMP] 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math>, as in Equation (3), successfully models pandemic shut-off, even in the dilute pandemic limit. However, as the <xref ref-type="fig" rid="figFigures 3-16">
     Figures 3-16
    </xref> insets show, many of the data-vs-model comparisons have the data trending above the model near the final 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        t 
      </mi> 
      <mo>
        = 
      </mo> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mi>
         F 
       </mi> 
      </msub> 
     </mrow> 
    </math> data point.</p>
   <p>Since Equation (3) for 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mi>
         D 
       </mi> 
      </msub> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mi>
         t 
       </mi> 
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         ) 
       </mo> 
      </mrow> 
     </mrow> 
    </math> is linear, using an Additional Modeling Parameter [AMP] 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         β 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math> in a higher order polynomial, may fit the 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mrow> 
       <mo>
         { 
       </mo> 
       <mrow> 
        <mi>
          p 
        </mi> 
        <mi>
          d 
        </mi> 
        <mi>
          f 
        </mi> 
       </mrow> 
       <mo>
         } 
       </mo> 
      </mrow> 
     </mrow> 
    </math> shape better. A quadratic function for 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mi>
         D 
       </mi> 
      </msub> 
     </mrow> 
    </math>:</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mi>
         D 
       </mi> 
      </msub> 
      <mo>
        = 
      </mo> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msub> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mrow> 
        <mn>
          1 
        </mn> 
        <mo>
          − 
        </mo> 
        <msub> 
         <mi>
           β 
         </mi> 
         <mi>
           S 
         </mi> 
        </msub> 
        <mi>
          Z 
        </mi> 
        <mo>
          + 
        </mo> 
        <msub> 
         <mi>
           α 
         </mi> 
         <mi>
           S 
         </mi> 
        </msub> 
        <msup> 
         <mi>
           Z 
         </mi> 
         <mn>
           2 
         </mn> 
        </msup> 
       </mrow> 
       <mo>
         ) 
       </mo> 
      </mrow> 
     </mrow> 
    </math>, (29)</p>
   <p>where 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mrow> 
       <mrow> 
        <mi>
          N 
        </mi> 
        <mrow> 
         <mo>
           ( 
         </mo> 
         <mi>
           t 
         </mi> 
         <mo>
           ) 
         </mo> 
        </mrow> 
       </mrow> 
       <mo>
         / 
       </mo> 
       <mrow> 
        <msub> 
         <mi>
           N 
         </mi> 
         <mi>
           o 
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        </msub> 
       </mrow> 
      </mrow> 
     </mrow> 
    </math> still approaches a constant at long times, as in Equation (6), then sets 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mo> 
      </mo> 
      <msup> 
       <mi>
         Z 
       </mi> 
       <mn>
         2 
       </mn> 
      </msup> 
      <mo>
        ≡ 
      </mo> 
      <mi>
        t 
      </mi> 
     </mrow> 
    </math>, giving this extension of Equation (3):</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mi>
         D 
       </mi> 
      </msub> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mi>
         t 
       </mi> 
       <mo>
         ) 
       </mo> 
      </mrow> 
      <mo>
        = 
      </mo> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msub> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mrow> 
        <mn>
          1 
        </mn> 
        <mo>
          − 
        </mo> 
        <msub> 
         <mi>
           β 
         </mi> 
         <mi>
           S 
         </mi> 
        </msub> 
        <msqrt> 
         <mi>
           t 
         </mi> 
        </msqrt> 
        <mo>
          + 
        </mo> 
        <msub> 
         <mi>
           α 
         </mi> 
         <mi>
           S 
         </mi> 
        </msub> 
        <mi>
          t 
        </mi> 
       </mrow> 
       <mo>
         ) 
       </mo> 
      </mrow> 
     </mrow> 
    </math>. (30)</p>
   <p>Values of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         β 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
      <mo>
        &gt; 
      </mo> 
      <mn>
        0 
      </mn> 
     </mrow> 
    </math> in Equation (30) allow the predicted 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mrow> 
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          </mi> 
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             ( 
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             t 
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             ) 
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           / 
         </mo> 
         <mrow> 
          <msub> 
           <mi>
             N 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
         </mrow> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
     </mrow> 
    </math> values to rise above the 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         β 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
      <mo>
        = 
      </mo> 
      <mn>
        0 
      </mn> 
     </mrow> 
    </math> model predictions, and to have a smaller doubling-time, for the same { 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
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        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
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      </msub> 
      <mo>
        , 
      </mo> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math>}. However, the best fit { 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msub> 
      <mo>
        , 
      </mo> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math>} values will also differ between the 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         β 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
      <mo>
        &gt; 
      </mo> 
      <mn>
        0 
      </mn> 
     </mrow> 
    </math> and 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        β 
      </mi> 
      <mo>
        ≡ 
      </mo> 
      <mn>
        0 
      </mn> 
     </mrow> 
    </math> cases, so these changes are relative.</p>
   <p>The new 
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      <mrow> 
       <mo>
         { 
       </mo> 
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      </mrow> 
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    </math> function for Equation (30) is:</p>
   <p>
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      <mtr> 
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                   t 
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               </mrow> 
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                 ) 
               </mo> 
              </mrow> 
             </mrow> 
             <mn>
               2 
             </mn> 
            </msup> 
            <mrow> 
             <mo>
               ( 
             </mo> 
             <mrow> 
              <mn>
                1 
              </mn> 
              <mo>
                + 
              </mo> 
              <mfrac> 
               <mn>
                 1 
               </mn> 
               <mn>
                 2 
               </mn> 
              </mfrac> 
              <msub> 
               <mi>
                 β 
               </mi> 
               <mi>
                 S 
               </mi> 
              </msub> 
              <msqrt> 
               <mi>
                 t 
               </mi> 
              </msqrt> 
             </mrow> 
             <mo>
               ) 
             </mo> 
            </mrow> 
           </mrow> 
           <mo>
             ] 
           </mo> 
          </mrow> 
         </mrow> 
        </mrow> 
       </mtd> 
      </mtr> 
     </mtable> 
    </math>. (31)</p>
   <p>When 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mrow> 
       <mo>
         { 
       </mo> 
       <mrow> 
        <mi>
          p 
        </mi> 
        <mi>
          d 
        </mi> 
        <mi>
          f 
        </mi> 
       </mrow> 
       <mo>
         } 
       </mo> 
      </mrow> 
      <mo>
        = 
      </mo> 
      <mn>
        0 
      </mn> 
     </mrow> 
    </math> in Equation (31), it estimates an end-point for the pandemic at:</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          E 
        </mi> 
        <mi>
          N 
        </mi> 
        <mi>
          D 
        </mi> 
       </mrow> 
      </msub> 
      <mo>
        = 
      </mo> 
      <mrow> 
       <mn>
         4 
       </mn> 
       <mo>
         / 
       </mo> 
       <mrow> 
        <msubsup> 
         <mi>
           β 
         </mi> 
         <mi>
           S 
         </mi> 
         <mn>
           2 
         </mn> 
        </msubsup> 
       </mrow> 
      </mrow> 
     </mrow> 
    </math>, (32)</p>
   <p>while predicting this maximum number of pandemic cases at 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          E 
        </mi> 
        <mi>
          N 
        </mi> 
        <mi>
          D 
        </mi> 
       </mrow> 
      </msub> 
     </mrow> 
    </math>:</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        N 
      </mi> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mrow> 
        <msub> 
         <mi>
           t 
         </mi> 
         <mrow> 
          <mi>
            E 
          </mi> 
          <mi>
            N 
          </mi> 
          <mi>
            D 
          </mi> 
         </mrow> 
        </msub> 
       </mrow> 
       <mo>
         ) 
       </mo> 
      </mrow> 
      <mo>
        = 
      </mo> 
      <msub> 
       <mi>
         N 
       </mi> 
       <mi>
         o 
       </mi> 
      </msub> 
      <mi>
        exp 
      </mi> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mrow> 
         <mrow> 
          <msub> 
           <mi>
             K 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
         </mrow> 
         <mo>
           / 
         </mo> 
         <mrow> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mrow> 
            <msub> 
             <mi>
               α 
             </mi> 
             <mi>
               S 
             </mi> 
            </msub> 
            <mo>
              − 
            </mo> 
            <mfrac> 
             <mn>
               1 
             </mn> 
             <mn>
               4 
             </mn> 
            </mfrac> 
            <msubsup> 
             <mi>
               β 
             </mi> 
             <mi>
               S 
             </mi> 
             <mn>
               2 
             </mn> 
            </msubsup> 
           </mrow> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
     </mrow> 
    </math>. (33)</p>
   <p>As an example, this augmented model was applied to CoVID-19 evolution in Italy. As shown in <xref ref-type="fig" rid="fig17">
     Figure 17
    </xref>, this Equation (31) 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mrow> 
       <mo>
         { 
       </mo> 
       <mrow> 
        <mi>
          p 
        </mi> 
        <mi>
          d 
        </mi> 
        <mi>
          f 
        </mi> 
       </mrow> 
       <mo>
         } 
       </mo> 
      </mrow> 
     </mrow> 
    </math> function gives a better fit to the observed number of daily new CoVID-19 cases.</p>
   <fig id="fig17" position="float">
    <label>Figure 17</label>
    <caption>
     <title>Figure 17. Predicted ITALY CoVID-19 results, using an augmented 2-parameter {

      <math display="inline" xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
  
        <msub> 
   
         <mi>
          
    α
   
         </mi> 
   
         <mi>
          
    S
   
         </mi> 
  
        </msub> 
  
        <mo>
         
   ,
  
        </mo>
  
        <msub> 
   
         <mi>
          
    β
   
         </mi> 
   
         <mi>
          
    S
   
         </mi> 
  
        </msub> 
 
       </mrow>

      </math>} Social Mitigation model. Total number of CoVID-19 cases is much less than <xref ref-type="fig" rid="fig12">
       Figure 12
      </xref>, but the model post-peak drop is much steeper, making this a likely best-case result.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/2313106-rId389.jpeg?20250603091021" />
   </fig>
   <p>In this augmented model, the initial doubling-time of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msubsup> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
       <mrow> 
        <mi>
          i 
        </mi> 
        <mi>
          n 
        </mi> 
        <mi>
          i 
        </mi> 
        <mi>
          t 
        </mi> 
        <mi>
          i 
        </mi> 
        <mi>
          a 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msubsup> 
      <mo>
        ≈ 
      </mo> 
      <mn>
        2.5566 
      </mn> 
      <mtext>
          
      </mtext> 
      <mtext>
        days 
      </mtext> 
     </mrow> 
    </math>, along with estimates for the Mitigation Measure parameters of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
      <mo>
        ≈ 
      </mo> 
      <mrow> 
       <mrow> 
        <mn>
          0.04583 
        </mn> 
       </mrow> 
       <mo>
         / 
       </mo> 
       <mrow> 
        <mtext>
          day 
        </mtext> 
       </mrow> 
      </mrow> 
     </mrow> 
    </math> and 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         β 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
      <mo>
        ≈ 
      </mo> 
      <mo>
        + 
      </mo> 
      <mn>
        0.1725 
      </mn> 
     </mrow> 
    </math>, combine to significantly reduce the projected maximum number of CoVID-19 cases down to 264,820 which is about 7X less compared to using 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math> alone, as in <xref ref-type="fig" rid="fig12">
     Figure 12
    </xref>. This augmented model sets an estimated pandemic peak at 3/29/2020, with a projected pandemic end-point around 7/7/2020, which is also significantly more optimistic.</p>
   <p>The true CoVID-19 pandemic progress is likely to be in between <xref ref-type="fig" rid="fig12">
     Figure 12
    </xref> as a worst-case, and <xref ref-type="fig" rid="fig17">
     Figure 17
    </xref> as a best-case projection. The geometric mean of the <xref ref-type="fig" rid="fig12">
     Figure 12
    </xref> and <xref ref-type="fig" rid="fig17">
     Figure 17
    </xref> results set an average of 683,500 cases for Italy at the CoVID-19 pandemic end. These bounds also highlight the amount of uncertainty that is intrinsic to these empirically based methods.</p>
  </sec><sec id="s8">
   <title>
    <xref ref-type="bibr" rid="scirp.143046-"></xref>8. Summary and Conclusions</title>
   <p>The standard exponential for modeling pandemics starts with an 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         N 
       </mi> 
       <mi>
         o 
       </mi> 
      </msub> 
     </mrow> 
    </math> known number of initial cases at some reference time 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        t 
      </mi> 
      <mo>
        = 
      </mo> 
      <mn>
        0 
      </mn> 
     </mrow> 
    </math>. Epidemiologists work to determine a pandemic growth factor 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         K 
       </mi> 
       <mi>
         D 
       </mi> 
      </msub> 
     </mrow> 
    </math>, which sets the doubling-time 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mi>
         D 
       </mi> 
      </msub> 
     </mrow> 
    </math> for the number of pandemic cases.</p>
   <p>The CoVID-19 disease, caused by the SARS-CoV-2 coronavirus pathogen, initially showed both regional and global exponential growth. It resulted in a doubling-time of 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mi>
         D 
       </mi> 
      </msub> 
      <mo>
        ≈ 
      </mo> 
      <mn>
        2.02 
      </mn> 
      <mtext>
          
      </mtext> 
      <mtext>
        days 
      </mtext> 
     </mrow> 
    </math> for the US, as highlighted in <xref ref-type="fig" rid="fig1">
     Figure 1
    </xref>.</p>
   <p>An exponential growth normally only halts when it runs out of materials. In epidemiology that point often occurs when there are virtually no more uninfected people left, which we call a saturated pandemic. The exponential growth function is only applicable when infection rates are much lower than saturation, which we call a dilute pandemic.</p>
   <p>A modification to exponential growth is developed here, which allows ratio of the number of pandemic cases, 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        N 
      </mi> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mi>
         t 
       </mi> 
       <mo>
         ) 
       </mo> 
      </mrow> 
     </mrow> 
    </math>, compared to its 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         N 
       </mi> 
       <mi>
         o 
       </mi> 
      </msub> 
     </mrow> 
    </math> initial value at 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        t 
      </mi> 
      <mo>
        = 
      </mo> 
      <mn>
        0 
      </mn> 
     </mrow> 
    </math>:</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <munder> 
       <mrow> 
        <mi>
          lim 
        </mi> 
       </mrow> 
       <mrow> 
        <mi>
          t 
        </mi> 
        <mo>
          → 
        </mo> 
        <mo>
          + 
        </mo> 
        <mi>
          ∞ 
        </mi> 
       </mrow> 
      </munder> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mrow> 
         <mrow> 
          <mi>
            N 
          </mi> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mi>
             t 
           </mi> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
         <mo>
           / 
         </mo> 
         <mrow> 
          <msub> 
           <mi>
             N 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
         </mrow> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
      <mo>
        = 
      </mo> 
      <mi>
        M 
      </mi> 
     </mrow> 
    </math>, (34)</p>
   <p>to approach a final constant, denoted 
    <math display="inline" xmlns="http://www.w3.org/1998/Math/MathML"> <mi>
       M 
     </mi> 
    </math>, while still being in a dilute pandemic condition. This result is attributed to the inclusion of society-wide Mitigation Measures to stop pandemic growth, before the value of 
    <math display="inline" xmlns="http://www.w3.org/1998/Math/MathML"> <mi>
       M 
     </mi> 
    </math> reaches the whole population value.</p>
   <p>
    <xref ref-type="bibr" rid="scirp.143046-"></xref>Society-wide Mitigation Measures aim to progressively lengthen the 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mi>
         D 
       </mi> 
      </msub> 
     </mrow> 
    </math> doubling-time, essentially making 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mi>
         D 
       </mi> 
      </msub> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mi>
         t 
       </mi> 
       <mo>
         ) 
       </mo> 
      </mrow> 
     </mrow> 
    </math>. Most analyses presented here used a linear function of time as the simplest non-constant model for 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mi>
         D 
       </mi> 
      </msub> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mi>
         t 
       </mi> 
       <mo>
         ) 
       </mo> 
      </mrow> 
     </mrow> 
    </math>:</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mi>
         D 
       </mi> 
      </msub> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mi>
         t 
       </mi> 
       <mo>
         ) 
       </mo> 
      </mrow> 
      <mo>
        ≡ 
      </mo> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msub> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mrow> 
        <mn>
          1 
        </mn> 
        <mo>
          + 
        </mo> 
        <msub> 
         <mi>
           α 
         </mi> 
         <mi>
           S 
         </mi> 
        </msub> 
        <mi>
          t 
        </mi> 
       </mrow> 
       <mo>
         ) 
       </mo> 
      </mrow> 
     </mrow> 
    </math>, (35)</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         K 
       </mi> 
       <mi>
         D 
       </mi> 
      </msub> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mi>
         t 
       </mi> 
       <mo>
         ) 
       </mo> 
      </mrow> 
      <mo>
        ≡ 
      </mo> 
      <mfrac> 
       <mrow> 
        <mi>
          ln 
        </mi> 
        <mn>
          2 
        </mn> 
       </mrow> 
       <mrow> 
        <msub> 
         <mi>
           t 
         </mi> 
         <mi>
           D 
         </mi> 
        </msub> 
        <mrow> 
         <mo>
           ( 
         </mo> 
         <mi>
           t 
         </mi> 
         <mo>
           ) 
         </mo> 
        </mrow> 
       </mrow> 
      </mfrac> 
      <mo>
        = 
      </mo> 
      <mrow> 
       <mrow> 
        <mrow> 
         <mo>
           ( 
         </mo> 
         <mrow> 
          <mi>
            ln 
          </mi> 
          <mn>
            2 
          </mn> 
         </mrow> 
         <mo>
           ) 
         </mo> 
        </mrow> 
       </mrow> 
       <mo>
         / 
       </mo> 
       <mrow> 
        <mrow> 
         <mo>
           [ 
         </mo> 
         <mrow> 
          <msub> 
           <mi>
             t 
           </mi> 
           <mrow> 
            <mi>
              d 
            </mi> 
            <mi>
              b 
            </mi> 
            <mi>
              l 
            </mi> 
           </mrow> 
          </msub> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mrow> 
            <mn>
              1 
            </mn> 
            <mo>
              + 
            </mo> 
            <msub> 
             <mi>
               α 
             </mi> 
             <mi>
               S 
             </mi> 
            </msub> 
            <mi>
              t 
            </mi> 
           </mrow> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
         <mo>
           ] 
         </mo> 
        </mrow> 
       </mrow> 
      </mrow> 
      <mo>
        ≡ 
      </mo> 
      <mrow> 
       <mrow> 
        <msub> 
         <mi>
           K 
         </mi> 
         <mi>
           o 
         </mi> 
        </msub> 
       </mrow> 
       <mo>
         / 
       </mo> 
       <mrow> 
        <mrow> 
         <mo>
           ( 
         </mo> 
         <mrow> 
          <mn>
            1 
          </mn> 
          <mo>
            + 
          </mo> 
          <msub> 
           <mi>
             α 
           </mi> 
           <mi>
             S 
           </mi> 
          </msub> 
          <mi>
            t 
          </mi> 
         </mrow> 
         <mo>
           ) 
         </mo> 
        </mrow> 
       </mrow> 
      </mrow> 
     </mrow> 
    </math>, (36)</p>
   <p>where 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mi>
         D 
       </mi> 
      </msub> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mrow> 
        <mi>
          t 
        </mi> 
        <mo>
          = 
        </mo> 
        <mn>
          0 
        </mn> 
       </mrow> 
       <mo>
         ) 
       </mo> 
      </mrow> 
      <mo>
        ≡ 
      </mo> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          d 
        </mi> 
        <mi>
          b 
        </mi> 
        <mi>
          l 
        </mi> 
       </mrow> 
      </msub> 
     </mrow> 
    </math>, and 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         K 
       </mi> 
       <mi>
         D 
       </mi> 
      </msub> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mrow> 
        <mi>
          t 
        </mi> 
        <mo>
          = 
        </mo> 
        <mn>
          0 
        </mn> 
       </mrow> 
       <mo>
         ) 
       </mo> 
      </mrow> 
      <mo>
        ≡ 
      </mo> 
      <msub> 
       <mi>
         K 
       </mi> 
       <mi>
         o 
       </mi> 
      </msub> 
     </mrow> 
    </math>. Here, 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math> is a new Social Mitigation Parameter (SMP), to quantify societal Mitigation Measures. This Equation (35) extension of pure exponential growth gives:</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        N 
      </mi> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mi>
         t 
       </mi> 
       <mo>
         ) 
       </mo> 
      </mrow> 
      <mo>
        = 
      </mo> 
      <msub> 
       <mi>
         N 
       </mi> 
       <mi>
         o 
       </mi> 
      </msub> 
      <mi>
        exp 
      </mi> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mo>
          + 
        </mo> 
        <mrow> 
         <mrow> 
          <msub> 
           <mi>
             K 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
          <mi>
            t 
          </mi> 
         </mrow> 
         <mo>
           / 
         </mo> 
         <mrow> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mrow> 
            <mn>
              1 
            </mn> 
            <mo>
              + 
            </mo> 
            <msub> 
             <mi>
               α 
             </mi> 
             <mi>
               S 
             </mi> 
            </msub> 
            <mi>
              t 
            </mi> 
           </mrow> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
     </mrow> 
    </math>, (37)</p>
   <p>as an empirical equation for modeling CoVID-19 spread. Since both 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         K 
       </mi> 
       <mi>
         o 
       </mi> 
      </msub> 
     </mrow> 
    </math> and 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math> in Equation (5) have the same units, their ratio is a dimensionless number. The long-term limit of Equation (37) gives:</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <munder> 
       <mrow> 
        <mi>
          lim 
        </mi> 
       </mrow> 
       <mrow> 
        <mi>
          t 
        </mi> 
        <mo>
          → 
        </mo> 
        <mo>
          + 
        </mo> 
        <mi>
          ∞ 
        </mi> 
       </mrow> 
      </munder> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mrow> 
         <mrow> 
          <mi>
            N 
          </mi> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mi>
             t 
           </mi> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
         <mo>
           / 
         </mo> 
         <mrow> 
          <msub> 
           <mi>
             N 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
         </mrow> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
      <mo>
        = 
      </mo> 
      <mi>
        exp 
      </mi> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mo>
          + 
        </mo> 
        <mrow> 
         <mrow> 
          <msub> 
           <mi>
             K 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
         </mrow> 
         <mo>
           / 
         </mo> 
         <mrow> 
          <msub> 
           <mi>
             α 
           </mi> 
           <mi>
             S 
           </mi> 
          </msub> 
         </mrow> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
     </mrow> 
    </math>, (38)</p>
   <p>setting a final value for the Equation (34) constant 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mi>
       M 
     </mi> 
    </math>, allowing these predictions to be applicable to the dilute pandemic limit. The CoVID-19 number of estimated cases per day is given by:</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mrow> 
       <mo>
         { 
       </mo> 
       <mrow> 
        <mi>
          p 
        </mi> 
        <mi>
          d 
        </mi> 
        <mi>
          f 
        </mi> 
       </mrow> 
       <mo>
         } 
       </mo> 
      </mrow> 
      <mo>
        = 
      </mo> 
      <mfrac> 
       <mtext>
         d 
       </mtext> 
       <mrow> 
        <mtext>
          d 
        </mtext> 
        <mi>
          t 
        </mi> 
       </mrow> 
      </mfrac> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mrow> 
         <mrow> 
          <mi>
            N 
          </mi> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mi>
             t 
           </mi> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
         <mo>
           / 
         </mo> 
         <mrow> 
          <msub> 
           <mi>
             N 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
         </mrow> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
     </mrow> 
    </math>, (39)</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <munder> 
       <mrow> 
        <mi>
          lim 
        </mi> 
       </mrow> 
       <mrow> 
        <mi>
          t 
        </mi> 
        <mo>
          → 
        </mo> 
        <mo>
          + 
        </mo> 
        <mi>
          ∞ 
        </mi> 
        <mo>
          , 
        </mo> 
        <msub> 
         <mi>
           α 
         </mi> 
         <mi>
           S 
         </mi> 
        </msub> 
        <mo>
          &gt; 
        </mo> 
        <mn>
          0 
        </mn> 
       </mrow> 
      </munder> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mrow> 
         <mo>
           { 
         </mo> 
         <mrow> 
          <mi>
            p 
          </mi> 
          <mi>
            d 
          </mi> 
          <mi>
            f 
          </mi> 
         </mrow> 
         <mo>
           } 
         </mo> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
      <mo>
        ~ 
      </mo> 
      <mfrac> 
       <mrow> 
        <mrow> 
         <mo>
           { 
         </mo> 
         <mrow> 
          <mtext>
            Constant 
          </mtext> 
         </mrow> 
         <mo>
           } 
         </mo> 
        </mrow> 
       </mrow> 
       <mrow> 
        <msup> 
         <mrow> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mrow> 
            <msub> 
             <mi>
               α 
             </mi> 
             <mi>
               S 
             </mi> 
            </msub> 
            <mi>
              t 
            </mi> 
           </mrow> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
         <mn>
           2 
         </mn> 
        </msup> 
       </mrow> 
      </mfrac> 
     </mrow> 
    </math>, (40)</p>
   <p>which combines an initial exponential rise with “long tail” at large times. In this model, new CoVID-19 cases can continue to arise for a long time, even with significant Mitigation Measures in place.</p>
   <p>Analysis of available CoVID-19 data using this model shows that it can match observed data fairly well, both from various US states <xref ref-type="fig" rid="figFigures 3-8">
     Figures 3-8
    </xref>, as well as for different global countries <xref ref-type="fig" rid="figFigures 9-16">
     Figures 9-16
    </xref>. However, using a single parameter to encompass all societal Mitigation Measures often gives a slightly larger slope on a log-plot, compared to the latest measured data values, which makes this model a likely worst-case estimate.</p>
   <p>A second data-fitting parameter 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         β 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math> was also used in an augmented model, to better fit the 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mrow> 
       <mo>
         { 
       </mo> 
       <mrow> 
        <mi>
          p 
        </mi> 
        <mi>
          d 
        </mi> 
        <mi>
          f 
        </mi> 
       </mrow> 
       <mo>
         } 
       </mo> 
      </mrow> 
     </mrow> 
    </math> data:</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mi>
        N 
      </mi> 
      <mrow> 
       <mo>
         ( 
       </mo> 
       <mi>
         t 
       </mi> 
       <mo>
         ) 
       </mo> 
      </mrow> 
      <mo>
        = 
      </mo> 
      <msub> 
       <mi>
         N 
       </mi> 
       <mi>
         o 
       </mi> 
      </msub> 
      <mi>
        exp 
      </mi> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mo>
          + 
        </mo> 
        <mrow> 
         <mrow> 
          <msub> 
           <mi>
             K 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
          <mi>
            t 
          </mi> 
         </mrow> 
         <mo>
           / 
         </mo> 
         <mrow> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mrow> 
            <mn>
              1 
            </mn> 
            <mo>
              − 
            </mo> 
            <msub> 
             <mi>
               β 
             </mi> 
             <mi>
               S 
             </mi> 
            </msub> 
            <msqrt> 
             <mi>
               t 
             </mi> 
            </msqrt> 
            <mo>
              + 
            </mo> 
            <msub> 
             <mi>
               α 
             </mi> 
             <mi>
               S 
             </mi> 
            </msub> 
            <mi>
              t 
            </mi> 
           </mrow> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
     </mrow> 
    </math>, (41)</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mtext>
        max 
      </mtext> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mrow> 
         <mrow> 
          <mi>
            N 
          </mi> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mi>
             t 
           </mi> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
         <mo>
           / 
         </mo> 
         <mrow> 
          <msub> 
           <mi>
             N 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
         </mrow> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
      <mo>
        = 
      </mo> 
      <mtext>
        exp 
      </mtext> 
      <mrow> 
       <mo>
         [ 
       </mo> 
       <mrow> 
        <mo>
          + 
        </mo> 
        <mrow> 
         <mrow> 
          <msub> 
           <mi>
             K 
           </mi> 
           <mi>
             o 
           </mi> 
          </msub> 
         </mrow> 
         <mo>
           / 
         </mo> 
         <mrow> 
          <mrow> 
           <mo>
             ( 
           </mo> 
           <mrow> 
            <msub> 
             <mi>
               α 
             </mi> 
             <mi>
               S 
             </mi> 
            </msub> 
            <mo>
              − 
            </mo> 
            <mfrac> 
             <mn>
               1 
             </mn> 
             <mn>
               4 
             </mn> 
            </mfrac> 
            <msubsup> 
             <mi>
               β 
             </mi> 
             <mi>
               S 
             </mi> 
             <mn>
               2 
             </mn> 
            </msubsup> 
           </mrow> 
           <mo>
             ) 
           </mo> 
          </mrow> 
         </mrow> 
        </mrow> 
       </mrow> 
       <mo>
         ] 
       </mo> 
      </mrow> 
     </mrow> 
    </math>, (42)</p>
   <p>
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          E 
        </mi> 
        <mi>
          N 
        </mi> 
        <mi>
          D 
        </mi> 
       </mrow> 
      </msub> 
      <mo>
        = 
      </mo> 
      <mrow> 
       <mn>
         4 
       </mn> 
       <mo>
         / 
       </mo> 
       <mrow> 
        <msubsup> 
         <mi>
           β 
         </mi> 
         <mi>
           S 
         </mi> 
         <mn>
           2 
         </mn> 
        </msubsup> 
       </mrow> 
      </mrow> 
     </mrow> 
    </math>, (43)</p>
   <p>where 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mrow> 
        <mi>
          E 
        </mi> 
        <mi>
          N 
        </mi> 
        <mi>
          D 
        </mi> 
       </mrow> 
      </msub> 
     </mrow> 
    </math> becomes an estimated pandemic end-point, where zero new CoVID-19 cases per day could occur.</p>
   <p>As a representative example, this augmented model was applied to the CoVID-19 data from Italy in <xref ref-type="fig" rid="fig17">
     Figure 17
    </xref>. Those results show that this augmented model allows a better fit to the observed number of new daily CoVID-19 cases, but the absence of a CoVID-19 tail in its 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mrow> 
       <mo>
         { 
       </mo> 
       <mrow> 
        <mi>
          p 
        </mi> 
        <mi>
          d 
        </mi> 
        <mi>
          f 
        </mi> 
       </mrow> 
       <mo>
         } 
       </mo> 
      </mrow> 
     </mrow> 
    </math> function makes this { 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         K 
       </mi> 
       <mi>
         o 
       </mi> 
      </msub> 
      <mo>
        , 
      </mo> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
      <mo>
        , 
      </mo> 
      <msub> 
       <mi>
         β 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math>} augmented model a likely best-case result, with the original { 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         K 
       </mi> 
       <mi>
         o 
       </mi> 
      </msub> 
      <mo>
        , 
      </mo> 
      <msub> 
       <mi>
         α 
       </mi> 
       <mi>
         S 
       </mi> 
      </msub> 
     </mrow> 
    </math>} model being a likely worst-case estimate.</p>
   <p>This class of CoVID-19 pandemic models all enable pandemic shut-off even in the dilute pandemic limit, with only a small fraction of the total population being infected. These models also provide estimates for: 1) the maximum number of cases near pandemic shutoff, 2) the size and shape of the pandemic peak [ 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <mrow> 
       <mrow> 
        <mtext>
          d 
        </mtext> 
        <mi>
          N 
        </mi> 
        <mrow> 
         <mo>
           ( 
         </mo> 
         <mi>
           t 
         </mi> 
         <mo>
           ) 
         </mo> 
        </mrow> 
       </mrow> 
       <mo>
         / 
       </mo> 
       <mrow> 
        <mtext>
          d 
        </mtext> 
        <mi>
          t 
        </mi> 
       </mrow> 
      </mrow> 
     </mrow> 
    </math>], and 3) pandemic peak timing [ 
    <math xmlns="http://www.w3.org/1998/Math/MathML"> <mrow> 
      <msub> 
       <mi>
         t 
       </mi> 
       <mi>
         P 
       </mi> 
      </msub> 
     </mrow> 
    </math>]. These models and analyses may help enhance planning and preparation to maximize resource use, potentially increasing individual and collective CoVID-19 pandemic survival rates.</p>
  </sec>
 </body><back>
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</article>