<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v3.0 20080202//EN" "http://dtd.nlm.nih.gov/publishing/3.0/journalpublishing3.dtd">
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="3.0" xml:lang="en" article-type="research article">
 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">
    oju
   </journal-id>
   <journal-title-group>
    <journal-title>
     Open Journal of Urology
    </journal-title>
   </journal-title-group>
   <issn pub-type="epub">
    2160-5440
   </issn>
   <issn publication-format="print">
    2160-5629
   </issn>
   <publisher>
    <publisher-name>
     Scientific Research Publishing
    </publisher-name>
   </publisher>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="doi">
    10.4236/oju.2025.154015
   </article-id>
   <article-id pub-id-type="publisher-id">
    oju-142327
   </article-id>
   <article-categories>
    <subj-group subj-group-type="heading">
     <subject>
      Articles
     </subject>
    </subj-group>
    <subj-group subj-group-type="Discipline-v2">
     <subject>
      Medicine 
     </subject>
     <subject>
       Healthcare
     </subject>
    </subj-group>
   </article-categories>
   <title-group>
    Glandular Epispadias Repair: A Case Report
   </title-group>
   <contrib-group>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Armel Quentin
      </surname>
      <given-names>
       Essomba
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff1"> 
      <sup>1</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Frantz Epoupa
      </surname>
      <given-names>
       Ngalle
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff2"> 
      <sup>2</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Philip Fernandez
      </surname>
      <given-names>
       Owon’Abessolo
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff1"> 
      <sup>1</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Bright
      </surname>
      <given-names>
       Awondo-Che
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff2"> 
      <sup>2</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Achille Aurele
      </surname>
      <given-names>
       Mbassi
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff2"> 
      <sup>2</sup>
     </xref> 
     <xref ref-type="aff" rid="aff3"> 
      <sup>3</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Axel Stephane Nwaha
      </surname>
      <given-names>
       Makon
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff2"> 
      <sup>2</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Pierre Joseph
      </surname>
      <given-names>
       Fouda
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff2"> 
      <sup>2</sup>
     </xref> 
     <xref ref-type="aff" rid="aff3"> 
      <sup>3</sup>
     </xref>
    </contrib>
   </contrib-group> 
   <aff id="aff1">
    <addr-line>
     aDepartment of Surgery and Specialties, Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Douala, Cameroon
    </addr-line> 
   </aff> 
   <aff id="aff2">
    <addr-line>
     aDepartment of Surgery and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaoundé 1, Yaoundé, Cameroon
    </addr-line> 
   </aff> 
   <aff id="aff3">
    <addr-line>
     aUrology Service, Yaoundé Central Hospital, Yaoundé, Cameroon
    </addr-line> 
   </aff> 
   <pub-date pub-type="epub">
    <day>
     24
    </day> 
    <month>
     04
    </month>
    <year>
     2025
    </year>
   </pub-date> 
   <volume>
    15
   </volume> 
   <issue>
    04
   </issue>
   <fpage>
    133
   </fpage>
   <lpage>
    138
   </lpage>
   <history>
    <date date-type="received">
     <day>
      19,
     </day>
     <month>
      February
     </month>
     <year>
      2025
     </year>
    </date>
    <date date-type="published">
     <day>
      25,
     </day>
     <month>
      February
     </month>
     <year>
      2025
     </year> 
    </date> 
    <date date-type="accepted">
     <day>
      25,
     </day>
     <month>
      April
     </month>
     <year>
      2025
     </year> 
    </date>
   </history>
   <permissions>
    <copyright-statement>
     © Copyright 2014 by authors and Scientific Research Publishing Inc. 
    </copyright-statement>
    <copyright-year>
     2014
    </copyright-year>
    <license>
     <license-p>
      This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/
     </license-p>
    </license>
   </permissions>
   <abstract>
    <b>Introduction</b>
    <b>:</b> Epispadias is a rare form of urogenital congenital anomaly with cosmetic consequences on the quality of life. We hereby report the case of a 10-year-old male child presenting with glandular male epispadias treated using the penile disassembly Mitchell technique, for which cosmetic and functional outcomes were good. 
    <b>Case </b>
    <b>Presentation</b>
    <b>:</b> Our patient is a 10-year-old male with a history of penoplasty at 6 years of age, indicated for a penile abnormality and urinary incontinence, who presented to our facility with persistent urinary incontinence from an abnormal opening since birth. Examination revealed a tween boy having both testicles in the scrotum. He had a spade-like glans penis, ventral hooding, urethral meatal plaque at the dorsal aspect of the penis with no chordee. He was diagnosed with Isolated Male Epispadias (IME), for which he eventually had a Mitchell procedure under general anesthesia. About 4 weeks after the procedure, the patient was continent, with no urethrocutaneous fistula, and the cosmetic outcome was satisfactory. 
    <b>Conclusions:</b> Appropriate treatment, irrespective of age, could significantly improve patients’ quality of life.
   </abstract>
   <kwd-group> 
    <kwd>
     Epispadias
    </kwd> 
    <kwd>
      Mitchell Technique
    </kwd> 
    <kwd>
      Glandular
    </kwd>
   </kwd-group>
  </article-meta>
 </front>
 <body>
  <sec id="s1">
   <title>1. Introduction</title>
   <p>Isolated Male Epispadias (IME) is a rare component of urogenital congenital anomaly with an estimated incidence in Europe of around 0.6 per 100.000 live births <xref ref-type="bibr" rid="scirp.142327-1">
     [1]
    </xref>. There is limited about the prevalence of epispadias in Sub-Saharan Africa. It is usually detected at birth and treated in infancy and childhood period, and surgical treatment remains a challenge for reconstructive urologists <xref ref-type="bibr" rid="scirp.142327-1">
     [1]
    </xref>. The main objective of treatment is to achieve a cosmetic and functional outcome of the penis <xref ref-type="bibr" rid="scirp.142327-2">
     [2]
    </xref>. Several techniques have been described, including the Original Cantwell technique, which was later modified by Ransley and the Mitchell and Bagli technique, which has become popular <xref ref-type="bibr" rid="scirp.142327-3">
     [3]
    </xref> <xref ref-type="bibr" rid="scirp.142327-4">
     [4]
    </xref>. The Mitchell technique is our preferred method for the treatment of male epispadias. The purpose of this case report is to highlight the rarity of epispadias and to share our experience in surgical management using the Mitchell technique.</p>
  </sec><sec id="s2">
   <title>2. Case Presentation</title>
   <p>A 10-year-old male child with a relevant past surgical history of a penoplasty indicated for a penile anatomical abnormality and urinary incontinence at 6 years of age whose post-operative period was marked by continuous urinary incontinence and unsatisfactory cosmetic and anatomical outcome who presented with persistent urinary incontinence in the context of penile malformation since birth. Physical examination revealed a child with normal physical and psychomotor development in relation to his age. Normal scrotal morphology with bilateral testicles in place. A penile length of about 2 cm, ventral urethral plate on the dorsal aspect of the penis and the urethral meatal opening on the glandular penis (<xref ref-type="fig" rid="fig1">
     Figure 1
    </xref>). Thoraco-abdomino-pelvic CT scan and a cardiac ultrasound were done, which were normal. This was to rule out any other associated congenital abnormality. Pre-operative investigations, which included a complete blood count, coagulation profile, urine culture and antibiotic sensitivity, were done to identify any correctable abnormality and to ensure that there was no absolute contra-indication for surgery. Pre-anaesthetic consultation was done and classified as ASA 1. Intra-operatively, under general anaesthesia and orotracheal intubation, the patient was installed in the supine position. Cutaneous asepsis and sterile draping were done. Surgical repair was done using the Mitchell technique.</p>
   <fig id="fig1" position="float">
    <label>Figure 1</label>
    <caption>
     <title>Figure 1. Glandular epispadias.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/5001016-rId14.jpeg?20250428035218" />
   </fig>
   <fig id="fig2" position="float">
    <label>Figure 2</label>
    <caption>
     <title>Figure 2. Placement of traction sutures.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/5001016-rId15.jpeg?20250428035218" />
   </fig>
   <fig id="fig3" position="float">
    <label>Figure 3</label>
    <caption>
     <title>Figure 3. Dissection of the urethral plate up to the peno-pubic junction and separation of the corpora cavernosa.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="" />
   </fig>
   <fig id="fig3" position="float">
    <label>Figure 3</label>
    <caption>
     <title>Figure 3. Dissection of the urethral plate up to the peno-pubic junction and separation of the corpora cavernosa.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/5001016-rId16.jpeg?20250428035218" />
   </fig>
   <fig id="fig3" position="float">
    <label>Figure 3</label>
    <caption>
     <title>Figure 3. Dissection of the urethral plate up to the peno-pubic junction and separation of the corpora cavernosa.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/5001016-rId17.jpeg?20250428035218" />
   </fig>
   <fig id="fig4" position="float">
    <label>Figure 4</label>
    <caption>
     <title>Figure 4. Tubularization of the urethra and repositioning of the corpora cavernosa.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="" />
   </fig>
   <fig id="fig4" position="float">
    <label>Figure 4</label>
    <caption>
     <title>Figure 4. Tubularization of the urethra and repositioning of the corpora cavernosa.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/5001016-rId18.jpeg?20250428035218" />
   </fig>
   <fig id="fig4" position="float">
    <label>Figure 4</label>
    <caption>
     <title>Figure 4. Tubularization of the urethra and repositioning of the corpora cavernosa.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/5001016-rId19.jpeg?20250428035218" />
   </fig>
   <p>The penis was tracted using nylon 3.0 sutures (<xref ref-type="fig" rid="fig2">
     Figure 2
    </xref>). Dissection of the urethral plate and separation of the corpora cavernosa up to the peno-pubic junction (<xref ref-type="fig" rid="fig3">
     Figure 3
    </xref>). A size 8fr silicone catheter was tubularized over the urethral plate using polyglactin 4.0 continuous running sutures (<xref ref-type="fig" rid="fig4">
     Figure 4
    </xref>). Repositioning of the corpora cavernosa was done using vicryl 4.0. Glanduloplasty was done using vicryl 4.0 (<xref ref-type="fig" rid="fig5">
     Figure 5
    </xref>). Closure of the penile skin was then realized using vicryl 3.0 (<xref ref-type="fig" rid="fig6">
     Figure 6
    </xref>). The immediate post-operative period was uneventful and the silicone catheter was removed on day 10 post-operative. There was no urinary incontinence following removal of the transurethral catheter. The patient was reviewed at 1 month and 3 months at the outpatient clinic, and the patient was continent, and there was no urethrocutaneous fistula. The cosmetic outcome was satisfactory. In the long term, we plan to assess for erectile dysfunction.</p>
   <fig id="fig5" position="float">
    <label>Figure 5</label>
    <caption>
     <title>Figure 5. Glanduloplasty.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/5001016-rId20.jpeg?20250428035218" />
   </fig>
   <fig id="fig6" position="float">
    <label>Figure 6</label>
    <caption>
     <title>Figure 6. Closure of the penile skin.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/5001016-rId21.jpeg?20250428035218" />
   </fig>
  </sec><sec id="s3">
   <title>3. Discussion</title>
   <p>Glandular epispadias is a rare pathology with few cases described in the literature <xref ref-type="bibr" rid="scirp.142327-5">
     [5]
    </xref> <xref ref-type="bibr" rid="scirp.142327-6">
     [6]
    </xref>. It is often associated with the Bladder-Extrophy-Epispadias Complex (BEEC) <xref ref-type="bibr" rid="scirp.142327-7">
     [7]
    </xref>. It is a noticeable congenital anomaly that is always corrected in childhood. Spinoit et al. reported a mean age of 13 months, while Nerli et al. reported a mean age of 9.13 years in their series <xref ref-type="bibr" rid="scirp.142327-1">
     [1]
    </xref> <xref ref-type="bibr" rid="scirp.142327-8">
     [8]
    </xref>. This is quite similar to the age of our patient, who is 10 years old.</p>
   <p>Urinary incontinence, which was present, correlates with what is described in the literature <xref ref-type="bibr" rid="scirp.142327-2">
     [2]
    </xref> <xref ref-type="bibr" rid="scirp.142327-5">
     [5]
    </xref> <xref ref-type="bibr" rid="scirp.142327-6">
     [6]
    </xref> <xref ref-type="bibr" rid="scirp.142327-8">
     [8]
    </xref>. Pre-operatively, radiological investigations were done to ensure that there were no other underlying congenital anomalies. Amougou et al. and Kura et al. reported similar findings <xref ref-type="bibr" rid="scirp.142327-1">
     [1]
    </xref> <xref ref-type="bibr" rid="scirp.142327-9">
     [9]
    </xref>. However, a micturating cysto-urethrography was not done to ensure a good bladder capacity.</p>
   <p>The modified Cantwell-Ransley and the Mitchell techniques have been reported in the literature as a reliable repair procedure with good and cosmetically acceptable outcomes <xref ref-type="bibr" rid="scirp.142327-3">
     [3]
    </xref> <xref ref-type="bibr" rid="scirp.142327-4">
     [4]
    </xref>. Due to convenience, low risk of post-operative fistula and familiarity with the surgeon, the Mitchell repair technique was used in this case. The previous Cantwell’s technique describes a procedure where the corpora are mobilized, and the urethra is placed in a hypospadic position <xref ref-type="bibr" rid="scirp.142327-3">
     [3]
    </xref>. Ransley modified the Cantwell technique by doing an incision of the corpora with dorsomedial anastomosis above the urethra <xref ref-type="bibr" rid="scirp.142327-3">
     [3]
    </xref>. Mitchell and Bagli further pushed the technique whereby there was complete disassembly of the corpora and detachment of the urethral plate <xref ref-type="bibr" rid="scirp.142327-4">
     [4]
    </xref>. This complete disassembly was traditionally performed in BEEC complex. Amougou et al. and Spinoit et al. used the Mitchell technique and had favorable outcomes <xref ref-type="bibr" rid="scirp.142327-2">
     [2]
    </xref> <xref ref-type="bibr" rid="scirp.142327-9">
     [9]
    </xref>. Odzebe et al. used Cantwell’s technique and had a satisfactory outcome <xref ref-type="bibr" rid="scirp.142327-10">
     [10]
    </xref>.</p>
   <p>Complications such as urethrocutaneous fistulae, failed repair as evident with persistent urinary incontinence, hypospadias frequently occur following surgery. Post-operative fistulas are common with the modified Cantwell-Ransley procedure (5.5%) as compared to the Mitchel technique (2.4%), as reported by Hammouda et al. <xref ref-type="bibr" rid="scirp.142327-3">
     [3]
    </xref> <xref ref-type="bibr" rid="scirp.142327-11">
     [11]
    </xref>. Three months after the operation, our case was continent with no fistula formation. Satisfaction was attained in our case, which was similar to other cases described in the literature.</p>
  </sec><sec id="s4">
   <title>4. Conclusion</title>
   <p>Anatomical and functional restoration in cases of isolated male epispadias is safe and effective and has good outcomes. The inclusion of a large number of patients is needed to affirm this statement. Better mastery of surgical techniques leads to a better functional outcome.</p>
  </sec><sec id="s5">
   <title>Consent</title>
   <p>Written informed consent was obtained from the patient for publication of this case report and accompanying images.</p>
  </sec><sec id="s6">
   <title>Authors’ Contribution</title>
   <p>All the authors contributed to the research work. They read and agreed to the final version of the manuscript.</p>
  </sec>
 </body><back>
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</article>