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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="3.0" xml:lang="en" article-type="research article">
 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">
    tel
   </journal-id>
   <journal-title-group>
    <journal-title>
     Theoretical Economics Letters
    </journal-title>
   </journal-title-group>
   <issn pub-type="epub">
    2162-2078
   </issn>
   <issn publication-format="print">
    2162-2086
   </issn>
   <publisher>
    <publisher-name>
     Scientific Research Publishing
    </publisher-name>
   </publisher>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="doi">
    10.4236/tel.2025.152022
   </article-id>
   <article-id pub-id-type="publisher-id">
    tel-141880
   </article-id>
   <article-categories>
    <subj-group subj-group-type="heading">
     <subject>
      Articles
     </subject>
    </subj-group>
    <subj-group subj-group-type="Discipline-v2">
     <subject>
      Business 
     </subject>
     <subject>
       Economics
     </subject>
    </subj-group>
   </article-categories>
   <title-group>
    Creation of University or Academic Spin-Offs: A Study of Failure and Success Factors
   </title-group>
   <contrib-group>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Marlise There
      </surname>
      <given-names>
       Dias
      </given-names>
     </name>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Marcelo
      </surname>
      <given-names>
       Macedo
      </given-names>
     </name>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Geneia Lucas dos
      </surname>
      <given-names>
       Santos
      </given-names>
     </name>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Vinicius
      </surname>
      <given-names>
       Dezem
      </given-names>
     </name>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Girlane
      </surname>
      <given-names>
       Bondan
      </given-names>
     </name>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Miguel Angelo
      </surname>
      <given-names>
       Silveira
      </given-names>
     </name>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Roberta
      </surname>
      <given-names>
       Begrow
      </given-names>
     </name>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Daiane Souza
      </surname>
      <given-names>
       Alves
      </given-names>
     </name>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Louise de Lira Roedel
      </surname>
      <given-names>
       Botelho
      </given-names>
     </name>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Renan
      </surname>
      <given-names>
       Petri
      </given-names>
     </name>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Rodolfo Amando
      </surname>
      <given-names>
       Schmitz
      </given-names>
     </name>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Thayse Gasparetto
      </surname>
      <given-names>
       Cornélio
      </given-names>
     </name>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Diogo Henrique
      </surname>
      <given-names>
       Ropelato
      </given-names>
     </name>
    </contrib>
   </contrib-group> 
   <aff id="affnull">
    <addr-line>
     aPostgraduate Program in Knowledge Management and Engineering, Federal University of Santa Catarina, Florianopolis, Brazil
    </addr-line> 
   </aff> 
   <pub-date pub-type="epub">
    <day>
     28
    </day> 
    <month>
     03
    </month>
    <year>
     2025
    </year>
   </pub-date> 
   <volume>
    15
   </volume> 
   <issue>
    02
   </issue>
   <fpage>
    383
   </fpage>
   <lpage>
    421
   </lpage>
   <history>
    <date date-type="received">
     <day>
      26,
     </day>
     <month>
      December
     </month>
     <year>
      2024
     </year>
    </date>
    <date date-type="published">
     <day>
      8,
     </day>
     <month>
      December
     </month>
     <year>
      2024
     </year> 
    </date> 
    <date date-type="accepted">
     <day>
      8,
     </day>
     <month>
      April
     </month>
     <year>
      2025
     </year> 
    </date>
   </history>
   <permissions>
    <copyright-statement>
     © Copyright 2014 by authors and Scientific Research Publishing Inc. 
    </copyright-statement>
    <copyright-year>
     2014
    </copyright-year>
    <license>
     <license-p>
      This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/
     </license-p>
    </license>
   </permissions>
   <abstract>
    Sharing knowledge produced by university research is still a complex activity, especially when it comes to commercial exploitation. One way to share this knowledge is through the creation of these university or academic spin-offs. In this context, this article aims to identify the main factors of failure and success related to the creation of these spin-offs, through a systematic review of the literature. The results of the research made it possible to understand what motivates the failure or success of university or academic spin-offs based on the concepts found in the literature that guides this article. In addition, the factors identified in this research provide valuable insights for the development of strategies that allow structuring initiatives for the creation of better targeted and successful spin-offs. Therefore, it is possible to conclude that, regardless of the number of success or failure factors found in each category, all have their due importance, to a greater or lesser degree, as they directly impact the creation and maintenance of university or academic spin-offs.
   </abstract>
   <kwd-group> 
    <kwd>
     Academic Spin-Off
    </kwd> 
    <kwd>
      University Spin-Off
    </kwd> 
    <kwd>
      Failure Factors
    </kwd> 
    <kwd>
      Success Factors
    </kwd>
   </kwd-group>
  </article-meta>
 </front>
 <body>
  <sec id="s1">
   <title>1. Introduction</title>
   <p>One of the main responsibilities of universities is the development of scientific and technological knowledge, with broad expertise and impact linked to the progress of society (<xref ref-type="bibr" rid="scirp.141880-9">
     Calderón‑Hernández, Jiménez‑Zapata, &amp; Serna‑Gomez, 2020
    </xref>).</p>
   <p>In Brazil, the article 207 of the 1988 Federal Constitution (<xref ref-type="bibr" rid="scirp.141880-5">
     Brazil, 1988
    </xref>) states that the Brazilian public university can be defined by three main factors: teaching, research and extension. Through policies and regulations specific to and external to the institution, the community develops projects whose main objective is the generation of new knowledge or the evolution of existing knowledge (<xref ref-type="bibr" rid="scirp.141880-13">
     Czarnitzki &amp; Lopes-Bento, 2014
    </xref>).</p>
   <p>As a result, these projects can develop services or products with the potential to be shared with society, especially projects designed and implemented in public universities. However, Brazilian higher education does not envision the large-scale manufacturing and production of technologies developed by the academic community as part of its mission (<xref ref-type="bibr" rid="scirp.141880-6">
     Brazil, 1996
    </xref>).</p>
   <p>The solution to this dilemma presents itself in the possibility of transferring technology created in the institution to organizations that are capable of finalizing development and producing on a large scale. Therefore, universities need to strengthen the university-industry-government partnership and foster university entrepreneurship.</p>
   <p>It is worth noting that data from 2020 published by the Ministry of Science, Technology and Innovation—MCTI, through a report that presents data provided by Scientific, Technological and Innovation Institutions, indicate that of the research organizations, 199 are public and 135 institutions had requests for intellectual property protection or requests granted. Of these, 83 are Public Higher Education organizations and were responsible for 1571 requests for intellectual property protection of their creations (<xref ref-type="bibr" rid="scirp.141880-18">
     FORMICT, 2024
    </xref>). The report also points out that, although the Innovation Law allows Scientific, Technological and Innovation Institutions, including universities, to enter into technology transfer and licensing contracts for the right to use or exploit developed creations, of the 135 public institutions, only 58 had technology contracts signed in 2020, with Higher Education Institutions representing the majority.</p>
   <p>This information highlights the difficulties that universities, especially public universities, face in ensuring that their technological creations, the result of their projects, reach the target audience. Thus, the creation of university or academic spin-offs (spin-offs can be called by both nomenclatures referring to the same type of spin-off) emerges as an alternative for the results of research developed within universities to reach production and market bias. University or academic spin-offs consist of companies created with the objective of exploiting intellectual property held in academia (<xref ref-type="bibr" rid="scirp.141880-53">
     THE, 2022
    </xref>). Spin-offs combine a product or service to be marketed and the know-how of university members so that it is possible to explore new opportunities (<xref ref-type="bibr" rid="scirp.141880-10">
     Carayannis et al., 1998
    </xref>).</p>
   <p>There is relevance in creating this type of company, as it is a requirement evaluated in the rankings of entrepreneurial universities, including by the Ministry of Science, Technology and Innovation (<xref ref-type="bibr" rid="scirp.141880-33">
     MCTI, 2023
    </xref>). The Ministry of Science, Technology and Innovation produces an annual report in which it requests the number of spin-offs developed by these institutions. In the 2020 document, the information is that of the 199 Scientific, Technological and Innovation Institutions surveyed, only 31 developed Spin-offs.</p>
   <p>Furthermore, it is worth highlighting the relevance of the regional context in which a university or academic spin-off is created, since regional capacity has a significant influence and impact on the maintenance of the company that is being activated (<xref ref-type="bibr" rid="scirp.141880-41">
     Nesello et al., 2019
    </xref>). For academics, the study of the topic allows the acquisition of knowledge about the creation and adequate maintenance of university or academic spin-offs and, as a researcher, envisions a possibility of undertaking through this type of company.</p>
   <p>The creation and maintenance of a spin-off requires dedication, effort and resilience from those who will be its founders. In this sense, this article aims to answer the following question: what factors influence the failure and success of universities or academic spin-offs?</p>
  </sec><sec id="s2">
   <title>2. Spin-Off</title>
   <p>A spin-off is an organization created with new economic activities emerged from an existing company and that, through its support, becomes independent with their own viable structure (<xref ref-type="bibr" rid="scirp.141880-27">
     León, Salazar, &amp; Sánchez, 2022
    </xref>). The initial definition of spin-off pointed out by <xref ref-type="bibr" rid="scirp.141880-50">
     Rubio (2009)
    </xref>, focuses on partners or employees of the new company obtaining basic conditions for its creation in the development of a new economic activity associated with novelties produced in the original organization.</p>
   <p>The recognition of an organization of this type can be carried out when three premises are highlighted: it has linked to its emergence an organization that already exists and which the literature calls the mother organization; involve individuals who work and have varied functions within the parent organization; and whoever creates an organization (spin-off) leaves the parent organization to found a new company—Spin-off (<xref ref-type="bibr" rid="scirp.141880-48">
     Pirnay, Surlemont, &amp; Nlemvo, 2003
    </xref>).</p>
   <p>There are three spin-off models: reactive, proactive and non-offensive. The first of these refers to developing solutions in advance or when the objective is to maintain a certain competence that could be better developed outside the original organization. In the case of the proactive model, the spin-off is created to make the activities and/or products of the original company grow in the external market. It is suggested that a new company be developed so that it can have an innovative focus in order to work with new products and/or new markets (<xref ref-type="bibr" rid="scirp.141880-50">
     Rubio, 2009
    </xref>).</p>
   <p>Spin-offs arise from any type of organization, whether private or public, for-profit or not-for-profit, of products or services (<xref ref-type="bibr" rid="scirp.141880-10">
     Carayannis et al., 1998
    </xref>). The involvement of companies and universities in product and service development activities allows us to glimpse ways of exploring the assets and skills explored (<xref ref-type="bibr" rid="scirp.141880-11">
     Clarysse, Wright, &amp; Van de Velde, 2011
    </xref>).</p>
   <p>In the context of universities, transferring developed technology has been a challenge. One way to carry out this activity is through licensing, which presents some difficulty considering the imminent risk due to the level of maturity of the invention, that is, it is still in the very early stages of the product, process or service. In this context, university or academic spin-offs are suggested as a viable alternative capable of reducing tensions arising from this problem, as they are created with the specific purpose of transferring knowledge and technologies generated in universities, aiming at commercial exploitation (<xref ref-type="bibr" rid="scirp.141880-48">
     Pirnay, Surlemont, &amp; Nlemvo, 2003
    </xref>; <xref ref-type="bibr" rid="scirp.141880-11">
     Clarysse, Wright, &amp; Van de Velde, 2011
    </xref>).</p>
   <p>University or academic spin-offs arise so that technology-based processes, products or services produced by universities can be commercially exploited (<xref ref-type="bibr" rid="scirp.141880-50">
     Rubio, 2009
    </xref>). These are companies created by researchers from public institutions, employees, professors and students; those that intend to license technological creations from public institutions; and those that arise from public investment (<xref ref-type="bibr" rid="scirp.141880-45">
     OECD, 2001
    </xref>).</p>
   <p>Furthermore, this type of company, which emerges from academia, allows the university to fulfill its mission of providing society with solutions in the most diverse areas, such as social, economic, political and cultural areas; as well as favoring regional development and the country’s competitiveness (<xref ref-type="bibr" rid="scirp.141880-9">
     Calderón-Hernández, Jiménez-Zapata, &amp; Serna-Gomez, 2020
    </xref>; <xref ref-type="bibr" rid="scirp.141880-10">
     Carayannis et al., 1998
    </xref>). Universities are favorable environments for the creation of technology and are concerned that the inventions developed reach society and that society can benefit from academic production.</p>
   <p>Thus, knowledge launched on the market via spin-off can be offered in the following ways, considering the function of this type of company: providing knowledge; offering a product or service; and providing solutions to demands from the market, in order to mediate technology transfer (<xref ref-type="bibr" rid="scirp.141880-17">
     Fontes, 2005
    </xref>).</p>
   <p>
    <xref ref-type="bibr" rid="scirp.141880-39">
     Müller (2010)
    </xref> demonstrated that knowledge, the focus of technology transfer in academia, is highly heterogeneous. The study identifies three types of spin-offs based on the level of research outcomes—whether a product or service—and their connection to this type of organization, as shown in <xref ref-type="fig" rid="fig1">
     Figure 1
    </xref>.</p>
   <fig id="fig1" position="float">
    <label>Figure 1</label>
    <caption>
     <title>Source: <xref ref-type="bibr" rid="scirp.141880-39">
       Müller (2010)
      </xref>.Figure 1. Types of spin-offs according to the result to be transferred.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/1503138-rId14.jpeg?20250411091239" />
   </fig>
   <p>Another classification relating to the types of university or academic spin-offs highlights their members and the specificity of the activities that their members carry out, as idealized by <xref ref-type="bibr" rid="scirp.141880-48">
     Pirnay, Surlemont and Nlemvo (2003)
    </xref> and demonstrated in <xref ref-type="fig" rid="fig2">
     Figure 2
    </xref>.</p>
   <fig id="fig2" position="float">
    <label>Figure 2</label>
    <caption>
     <title>Source: <xref ref-type="bibr" rid="scirp.141880-48">
       Pirnay, Surlemont, &amp; Nlemvo (2003)
      </xref>.Figure 2. Typology of universities or academic spin-offs.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/1503138-rId15.jpeg?20250411091239" />
   </fig>
   <p>Analyzing <xref ref-type="fig" rid="fig2">
     Figure 2
    </xref>, “Type I” spin-offs involve academic researchers as members, with a focus on transferring technology in the form of a product. “Type II,” by contrast, also includes academic researchers but emphasizes tacit knowledge—know-how—aimed at providing services through the spin-off. “Type III” comprises students as members and centers on knowledge that results in a product as the business focus. Finally, “Type IV” also includes students but relies on tacit knowledge, leading to the provision of services as the spin-off’s core activity (<xref ref-type="bibr" rid="scirp.141880-48">
     Pirnay, Surlemont, &amp; Nlemvo, 2003
    </xref>).</p>
   <p>Regardless of the type of academic spin-off created, the founders’ skills are critical in determining the company’s pace of development and market impact, as well as its contribution to the university. Therefore, it is essential for universities to implement policies that incentivize spin-off creation as a means of technology transfer, fostering a secure environment for these companies to grow (<xref ref-type="bibr" rid="scirp.141880-39">
     Müller, 2010
    </xref>). The process of technology transfer in a university, since it arises from research and consequently generates new knowledge, will be strongly influenced by the type of knowledge generated and capable of being transferred. Aspects such as bureaucracy, especially in public universities, and intellectual protection of the technologies created may also affect the time it takes to create spin-offs with the aim of transferring technologies (<xref ref-type="bibr" rid="scirp.141880-39">
     Müller, 2010
    </xref>).</p>
   <p>It is important to highlight the way in which university or academic spin-offs act in the transformation process, enabling the knowledge produced by higher education institutions to be the focus of commercial exploitation: bringing the results of university research to the market in the form of technology, making knowledge accessible to the market and enabling the diversification of possible application areas, and being an active player in the transfer of technology from universities, identifying knowledge that can be taken to the market and commercially exploited, including adapting creations to specific contexts (<xref ref-type="bibr" rid="scirp.141880-17">
     Fontes, 2005
    </xref>).</p>
   <p>From the development of research which results in technology linked to innovative knowledge, be it a product, process or service, the process of creating a university or academic spin-off will begin. In order to add value to the technology generating the new company, it is suggested that the following requirements be met: (<xref ref-type="bibr" rid="scirp.141880-50">
     Rubio, 2009
    </xref>):</p>
   <p>•Confirm the market potential.</p>
   <p>•Have a level of maturity appropriate for the Market.</p>
   <p>•Have intellectual protection that guarantees the rights related to the technology.</p>
   <p>Based on applied research with public and academic authorities, <xref ref-type="bibr" rid="scirp.141880-40">
     Ndonzuau, Pirnay, and Surlemont (2022)
    </xref> developed a four-stage model for the creation of university or academic spin-offs, as illustrated in <xref ref-type="fig" rid="fig3">
     Figure 3
    </xref>.</p>
   <fig id="fig3" position="float">
    <label>Figure 3</label>
    <caption>
     <title>Source: <xref ref-type="bibr" rid="scirp.141880-40">
       Ndonzuau, Pirnay, &amp; Surlemont (2002)
      </xref>.Figure 3. Stages of the process of creating universities or academic spin-offs.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/1503138-rId16.jpeg?20250411091239" />
   </fig>
   <p>The research conducted with universities indicated that two main difficulties were encountered in phase 1 of the proposed model: academic culture and internal identification. Regarding culture, the university policy that encourages and promotes publications as a way of advancing research professors is cited. These aspects do not motivate university researchers to undertake projects, and publishing research can destroy the originality of a result that could be exploited commercially. Another issue is the ambiguous relationship between professors and financial returns from the results of their research: professors understand that funding is a means for research to be carried out, and when it comes to companies, financial returns are also part of the process. Finally, the authors highlighted the need to show academia that developing research that results in applicable technologies is a way of reaching society and taking the knowledge developed to it. Internal identification is related to the university’s ability to structure itself so that it is possible to train and advise those interested in undertaking projects and identify ideas that may be capable of being exploited commercially (<xref ref-type="bibr" rid="scirp.141880-40">
     Ndonzuau, Pirnay, &amp; Surlemont, 2002
    </xref>).</p>
   <p>In the second step of the model, ideas are developed into structured entrepreneurial projects. This transformation focuses on protecting and developing the new idea. The protection of the creation that will be the object of the project is concerned with identifying its creators and the possibility of protection, which will require technical knowledge and financial resources. When it comes to development, the creation of a prototype is proposed so that commercial exploitation can be identified; in addition, a business plan is also drawn up that demonstrates how commercial exploitation will be carried out (<xref ref-type="bibr" rid="scirp.141880-40">
     Ndonzuau, Pirnay, &amp; Surlemont, 2002
    </xref>). Furthermore, the financing required for this phase becomes a barrier for most university entrepreneurs (<xref ref-type="bibr" rid="scirp.141880-40">
     Ndonzuau, Pirnay, &amp; Surlemont, 2002
    </xref>).</p>
   <p>In phase three, the focus is on launching the university or academic spin-off on the market. Resources are a concern at this stage of the model and refer to both labor, i.e., personnel resources and their capabilities, as well as financial and material resources for implementation. Another issue at this stage is the relationship between the university and the spin-off. In the relationship between the spin-off and the mother university, the study is conducted on how the latter can assist the new company, whether through financial resources, assets for commercialization, or work structure. Furthermore, the relationship between researchers who are related to or in the spin-off and the mother university can generate a conflict of interest, in the case of favoritism towards the new company that is being created due to such relationship (<xref ref-type="bibr" rid="scirp.141880-40">
     Ndonzuau, Pirnay, &amp; Surlemont, 2002
    </xref>).</p>
   <p>Phase 4 of the <xref ref-type="bibr" rid="scirp.141880-40">
     Ndonzuau, Pirnay and Surlemont (2002)
    </xref> model is related to the risk of changing the location of the spin-off, since the technologies developed by this type of company are highly innovative, and changing the location may generate a lack of personnel and structure for the spin-off to operate if the location in which it is established does not favor its growth. Furthermore, the authors point out that due to financial issues, product-oriented spin-offs tend, at the beginning, to provide consulting services to finance their technologies and place them on the Market. If spin-offs maintain their initial strategy of providing consulting services, meeting local demand for technologies that the spin-off could produce would be compromised and the spin-off would lose the opportunity to be successful.</p>
   <p>The phases presented in <xref ref-type="fig" rid="fig3">
     Figure 3
    </xref> are not entirely independent, each influencing the other and all are relevant for the model to work (<xref ref-type="bibr" rid="scirp.141880-40">
     Ndonzuau, Pirnay, &amp; Surlemont, 2002
    </xref>). The model is not linear and each stage depends on the quality of what was achieved in the previous phase. And not every idea or opportunity considered interesting will be converted into the creation of academic or university spin-offs.</p>
   <p>Carrying out the suggested process presents obstacles, difficulties, impediments, and other resistances, and is not a simple activity to carry out, but it can be a way to be adopted in the process of creating academic or university spin-offs (<xref ref-type="bibr" rid="scirp.141880-40">
     Ndonzuau, Pirnay, &amp; Surlemont, 2002
    </xref>).</p>
   <p>Considering the aspects related to the process of creating universities or academic spin-offs, a variety of aspects that should be considered in their creation can be seen. Theory suggests that there are many factors that can contribute to the creation and maintenance of universities or academic spin-offs, therefore, this article aims to raise aspects related to the success and failure of this type of organization.</p>
  </sec><sec id="s3">
   <title>3. Methodology</title>
   <p>The article aims to investigate the factors that may motivate or hinder the success of creating and maintaining university spin-offs. The difference between motivating or hindering factors was determined based on concepts obtained in the articles studied and globally accepted trends in the literature through a systematic literature review (<xref ref-type="bibr" rid="scirp.141880-30">
     Macedo, 2022
    </xref>). To achieve this, a search was conducted in three databases—Scopus, Web of Science, and Emerald—using the constructs “university or academic spin-offs” and “framework.”</p>
   <p>There were few articles involving frameworks and most of the files found were from the academic spin-off or university spin-off constructs. The choice of the articles and its relevance to the research was made based on the analysis of the title, abstract and keywords. In total, 96 articles were found covering these constructs. Among these 96 articles, 78 articles were selected to identify success and failure factors. The main challenge was to extract the articles that cited negative and limiting aspects and aspects considered motivating and facilitating the development of spinoffs, based on the interpretation of the concepts found in these articles, and then group these factors into categories.</p>
   <p>To identify the success and failure factors, the steps necessary to carry out this research were presented in <xref ref-type="fig" rid="fig4">
     Figure 4
    </xref>.</p>
   <fig id="fig4" position="float">
    <label>Figure 4</label>
    <caption>
     <title>Source: Authors.Figure 4. Research phases.</title>
    </caption>
    <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/1503138-rId17.jpeg?20250411091239" />
   </fig>
   <p>Phase 1, reading and analyzing the articles, allowed us to identify which articles contained relevant information to achieve the objective of this research. Thus, the reading of the articles aimed to select the articles that contained in their content factors of failure and factors of success in the creation and maintenance of university spin-offs. At the same time, the articles were separated into a list of articles that presented factors of failure in the creation and maintenance of university spin-offs and another list with articles that reported aspects of the factors of success in the creation and maintenance of university spin-offs. In the end, of these 96 articles, 77 articles contained success and failure factors.</p>
   <p>In phase two, we identified what we call a list of factors, that is, by rereading the selected articles, we identified what we call success and failure factors. This list therefore contains success and failure factors identified in the creation and maintenance of university spin-offs. In addition to the success and failure factors included in the list, we also selected the articles from which each success and failure factor was extracted, as well as the author of each article. It is worth noting that the list of failure factors included 127 factors and the list of success factors presented 130 success factors. All these factors were extracted from the 77 articles analyzed.</p>
   <p>In phase three, through the analysis of each of the lists of failure factors and success factors, categories were created so that these factors could be grouped into each of them based on the relationship that exists between the categories and factors. Ten categories were listed for each type of success and failure factor. This grouping of categories and factors was carried out based on positive and negative concepts for the development of spinoffs extracted from the literature. All of these categories have their due influence and importance in this process; however, this study was limited to identifying them only, and did not determine which categories should be prioritized in the creation of spinoffs.</p>
   <p>In phase four, the identified factors were grouped into categories in which they had some relationship. In total, there were 127 failure factors and 130 success factors divided into each of these 10 categories according to the relationship between each of them.</p>
  </sec><sec id="s4">
   <title>4. Results and Discussion</title>
   <p>This chapter presents the results of the research following the methodology described in chapter 3 of methodology. The research was applied following the steps presented in phases 1 to 4, as shown in <xref ref-type="fig" rid="fig4">
     Figure 4
    </xref>. In addition, this topic presents a discussion on the topic through a comparison between the failure factors and success factors for the creation and maintenance of university spin-offs, as well as identifies the categories created to group the failure and success factors related to the creation and maintenance of university spin-offs, in order to point out aspects that hinder and encourage the creation and maintenance of university or academic spin-offs.</p>
   <sec id="s4_1">
    <title>4.1. Presentation of Research Results</title>
    <p>Phase 1: Reading and Analysis of Articles</p>
    <p>From the selected articles, factors that limit the development and growth of university or academic spin-offs were identified and classified as failure factors. Out of the 78 articles reviewed, 45 contained characteristics related to the failure of university or academic spin-offs. These factors were extracted from concepts considered negative and limiting to the development of spinoffs according to the authors’ concepts listed in <xref ref-type="table" rid="table1">
      Table 1
     </xref>.</p>
    <p>Phase 2: List of Failure Factors</p>
    <p>After analyzing the 45 articles, all identified failure factors were compiled into a table, resulting in 127 distinct factors. It is important to note that individual articles often mentioned multiple failure factors, meaning the total number of factors exceeds the number of articles analyzed. <xref ref-type="table" rid="table1">
      Table 1
     </xref> provides a detailed list of the failure factors associated with the creation of university spin-offs as identified in the reviewed articles.</p>
    <table-wrap id="table1">
     <label>
      <xref ref-type="table" rid="table1">
       Table 1
      </xref></label>
     <caption>
      <title>
       <xref ref-type="bibr" rid="scirp.141880-"></xref>Table 1. Failure factors table.</title>
     </caption>
     <table class="MsoTableGrid custom-table" border="0" cellspacing="0" cellpadding="0"> 
      <tr> 
       <td class="custom-bottom-td custom-top-td aleft" width="26.72%"><p style="text-align:left">Failure factors</p></td> 
       <td class="custom-bottom-td custom-top-td aleft" width="23.53%"><p style="text-align:left">Authors</p></td> 
       <td class="custom-bottom-td custom-top-td aleft" width="27.88%"><p style="text-align:left">Failure factors</p></td> 
       <td class="custom-bottom-td custom-top-td aleft" width="21.87%"><p style="text-align:left">Authors</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="26.72%"><p style="text-align:left">External features such as regional infrastructure</p></td> 
       <td class="custom-top-td aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-43">
          O’Shea, Chugh and Allen (2008)
         </xref></p></td> 
       <td class="custom-top-td aleft" width="27.88%"><p style="text-align:left">Lack of market-oriented research institutions</p></td> 
       <td class="custom-top-td aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Country and region specific differences</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Lack of best practices for entrepreneurship</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-35">
          Montiel-Campos (2018)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Being in an environment conducive to entrepreneurship</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-28">
          Lockett et al. (2005)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Lack of qualified professionals at the university for guidance</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-4">
          Botelho and Almeida (2011)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Evolution of the ecosystem in the spin-off region</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-1">
          Bagchi-Sen, Baines and Lawton Smith (2020)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Lack of a legal arrangement conducive to innovation</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-23">
          Hayter, Lubynsky and Maroulis (2017)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Lack of external support (where it is located)</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-22">
          Harrison and Leitch (2010)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Lack of an “entrepreneurial culture”</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-23">
          Hayter, Lubynsky and Maroulis (2017)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Infrastructure (environments conducive to innovation)</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-21">
          Gómez Gras et al. (2008)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Academic system</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Entrepreneurial competence</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-3">
          Bolzani, Rasmussen and Fini (2020)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Human capital</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-21">
          Gómez Gras et al. (2008)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Weak entrepreneurial culture and infrastructure</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-4">
          Botelho and Almeida (2011)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Homogeneous team composition</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-51">
          Santos and Teixeira (2012)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">University culture not conducive to technology transfer, culture clash between industry and academia</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón‑Hernández, Jiménez‑Zapata and Serna‑Gomez (2020)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Recruitment of personnel with connection to the market</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-60">
          Wennberg, Wiklund and Wright (2011)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Conceptual divergences,</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-12">
          Czakon, Jedynak and Konopka-Cupiał (2022)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Employee engagement</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-23">
          Hayter, Lubynsky and Maroulis (2017)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Involvement in entrepreneurial activity (studies of individual characteristics)</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-43">
          O’Shea, Chugh and Allen (2008)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Diverse team</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-28">
          Lockett et al. (2005)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Institutional and cultural studies</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-43">
          O’Shea, Chugh and Allen (2008)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Very young team</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-16">
          Fiorentino et al. (2022)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Existence of myths and misconceptions about academic entrepreneurship</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón‑Hernández, Jiménez‑Zapata and Serna‑Gomez (2020)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Delayed Human Resource Management</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Lack of a model to stimulate entrepreneurial culture</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-46">
          Oliveira (2015)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Human capital limitations</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-23">
          Hayter, Lubynsky and Maroulis (2017)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Lack of entrepreneurial skills, knowledge and</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Internal capabilities</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-20">
          Freitas et al. (2012)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Lack of training in entrepreneurship</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-42">
          Neves and Franco (2016)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Organizational characteristics Bureaucracy</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Internal governance conflicts</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref>; <xref ref-type="bibr" rid="scirp.141880-40">
          Ndonzuau, Pirnay and Surlemont (2002)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Conflict of interest</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref>; <xref ref-type="bibr" rid="scirp.141880-40">
          Ndonzuau, Pirnay and Surlemont (2002)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Difficulty in the project of enterprise</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-40">
          Ndonzuau, Pirnay and Surlemont (2002)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Insufficient political support</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Delayed management style</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Lack of public support</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-26">
          Kulkov et al. (2019)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Irrational management structure</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Lack of public policy</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-28">
          Lockett et al. (2005)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Lack of professional management</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-28">
          Lockett et al. (2005)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Vague beneficial interests</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Lack of growth</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-61">
          Yagüe-Perales and March-Chordà (2012)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Adaptation to the market</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-51">
          Santos and Teixeira (2012)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Lack of economies of scale</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Market-seeking alliances reduce the probability of failure, while technology-seeking alliances increase the probability of failure.</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-7">
          Bruneel et al. (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Lack of legitimacy with companies and universities</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-19">
          François and Philippart (2019)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Trade barriers</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-26">
          Kulkov et al. (2019)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Delayed Operation Philosophy</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Market demand</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-56">
          van Geenhuizen and Soetanto (2009)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Project management</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-51">
          Santos and Teixeira (2012)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Being away from the market</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-34">
          Modina et al. (2024)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Ambiguous corporate governance</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Lack of applicability of knowledge</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Individualism of entrepreneurs/researcher</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-42">
          Neves and Franco (2016)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Lack of application of knowledge</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-42">
          Neves and Franco (2016)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Business mismanagement</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-40">
          Ndonzuau, Pirnay and Surlemont (2002)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Lack of trust from future customers</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-51">
          Santos and Teixeira (2012)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Unable to separate spin-off and parent university</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-40">
          Ndonzuau, Pirnay and Surlemont (2002)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Government support</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-62">
          Zhang (2009)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Business-oriented management concerns</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Negative link between the inventor’s ongoing interaction with the university and with the spin-off</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-29">
          Laage-Hellman et al. (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Internal governance issues</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Suitable business model</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-31">
          Martínez-Martínez et al. (2021)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Management overload</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-56">
          van Geenhuizen and Soetanto (2009)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Little experience of entrepreneurs</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-51">
          Santos and Teixeira (2012)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Lack of external relationships</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-29">
          Laage-Hellman et al. (2020)
         </xref>; <xref ref-type="bibr" rid="scirp.141880-22">
          Harrison and Leitch (2010)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Contact networks</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-20">
          Freitas et al. (2012)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">lack of market selectivity - Business model analysis</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-4">
          Botelho and Almeida (2011)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Spin-off policies that offer little support.</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-4">
          Botelho and Almeida (2011)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Weak collaboration between universities and industry.</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-35">
          Montiel-Campos (2018)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Few incentives</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón‑Hernández, Jiménez‑Zapata and Serna‑Gomez (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Degree of technology maturity</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-62">
          Zhang (2009)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Support programs</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-56">
          van Geenhuizen and Soetanto (2009)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Negative impact-trying to over-anticipate customer expectations: proactive customer intelligence generation (PCIG)</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-8">
          Buratti, Profumo and Persico (2021)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Legal restrictions on spin-off creation</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón‑Hernández, Jiménez‑Zapata and Serna‑Gomez (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Technological ties maintained by academic entrepreneurs committed to serving the technological development of parent universities have a negative impact on the market performance of spin-offs</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-3">
          Bolzani, Rasmussen and Fini (2020)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Diversity of product and service categories offered by spin-offs.</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-2">
          Baines and Smith (2019)
         </xref>.</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Support in the development of business plans offered by public institutions</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-12">
          Czakon, Jedynak and Konopka-Cupiał (2022)
         </xref>;</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Insufficient financial support</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Lack of monetary incentives for researchers</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-37">
          Muscio, Quaglione and Ramaciotti (2016)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Venture capital</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-61">
          Yagüe-Perales and March-Chordà (2012)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Lack of institutional policy</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-37">
          Muscio, Quaglione and Ramaciotti (2016)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">High cost to generate spin-off </p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-44">
          Odei and Stejskal (2018)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Lack of policy</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-28">
          Lockett et al. (2005)
         </xref>; <xref ref-type="bibr" rid="scirp.141880-15">
          Fini et al. (2017)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Difficulty in obtaining financial support due to bureaucracy</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Internal regulations for the creation of spin-offs</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-37">
          Muscio, Quaglione and Ramaciotti (2016)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Lack of venture capital</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Lack of policy that motivates the creation of spin-offs</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-35">
          Montiel-Campos (2018)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Lack of resources</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-23">
          Hayter, Lubynsky and Maroulis (2017)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Technology stock - capacity to generate new technological innovations</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-21">
          Gómez Gras et al. (2008)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Lack of resources</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-42">
          Neves and Franco (2016)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Patenting</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-61">
          Yagüe-Perales and
         </xref>March-Chordà (2012)</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Lack of financial resources</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-57">
          Vega-Gómez et al. (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Lack of financial resources</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-26">
          Kulkov et al. (2019)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Resources and capabilities of the ttos ability to seek external financing</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-21">
          Gómez Gras et al. (2008)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Infrastructure</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-23">
          Hayter, Lubynsky and Maroulis (2017)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Support from the parent university</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-56">
          van Geenhuizen and Soetanto (2009)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Infrastructure</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-56">
          van Geenhuizen and Soetanto (2009)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Links with parent universities can also introduce liabilities that limit their market performance.</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-3">
          Bolzani, Rasmussen and Fini (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Risk of investing in SPIN-offs</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-36">
          Munari and Toschi (2011)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Lack of intervention by the university management team</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-19">
          François and Philippart (2019)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Inadequate type of financing</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-31">
          Martínez-Martínez et al. (2021)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Lack of infrastructural support.</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Difficulty accessing tangible resources such as structure and machinery</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-40">
          Ndonzuau, Pirnay and Surlemont (2002)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Lack of internal support (university)</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-22">
          Harrison and Leitch (2010)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Difficulty in raising funds</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-15">
          Fini et al. (2017)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Lack of internal relationship with the parent university</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-29">
          Laage-Hellman et al. (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Shortage of resources for investment</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-51">
          Santos and Teixeira (2012)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Lack of support from the home institution</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-51">
          Santos and Teixeira (2012)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Structure of resources and capabilities that the parent organization provides</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-61">
          Yagüe-Perales and March-Chordà (2012)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">The fact that the parent university was not properly asked to rescue a process that was failing.</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-19">
          François and Philippart (2019)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Lack of access to tangible resources</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-28">
          Lockett et al. (2005)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Minimum university-business-state integration</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón‑Hernández, Jiménez‑Zapata and Serna‑Gomez (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Lack of facilities</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Support measures provided by universities</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-21">
          Gómez Gras et al. (2008)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Lack of intangibles</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-28">
          Lockett et al. (2005)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">The attributes of universities such as human capital, commercial resources and institutional activities</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-43">
          O’Shea, Chugh and Allen (2008)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Lack of resources</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-40">
          Ndonzuau, Pirnay and Surlemont (2002)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Researchers ignore the institution’s formal process</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-15">
          Fini et al. (2017)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Insufficient investment</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-35">
          Montiel-Campos (2018)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Accommodation problems</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-56">
          van Geenhuizen and Soetanto (2009)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Non-Availability of Resources</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-40">
          Ndonzuau, Pirnay and Surlemont (2002)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Relationships that must be established between the spin-off company and its parent university</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-40">
          Ndonzuau, Pirnay and Surlemont (2002)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="26.72%"><p style="text-align:left">Bias on the part of venture capital firms against investing in asos</p></td> 
       <td class="aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-36">
          Munari and Toschi (2011)
         </xref></p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Financial issues to transform the invention into a developed technological product</p></td> 
       <td class="aleft" width="21.87%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-40">
          Ndonzuau, Pirnay and Surlemont (2002)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="26.72%"><p style="text-align:left">Cash flow problems</p></td> 
       <td class="custom-bottom-td aleft" width="23.53%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-56">
          van Geenhuizen and Soetanto (2009)
         </xref></p></td> 
       <td class="custom-bottom-td aleft" width="27.88%"><p style="text-align:left"></p></td> 
       <td class="custom-bottom-td aleft" width="21.87%"><p style="text-align:left"></p></td> 
      </tr> 
     </table>
    </table-wrap>
    <p>Phase 3: Definition of Categories</p>
    <p>In the articles researched, 127 factors were found that can lead a spin-off to failure. These factors were grouped into categories. Each of these categories grouped a set of failure factors. A total of ten categories were classified as shown in <xref ref-type="fig" rid="fig5">
      Figure 5
     </xref>.</p>
    <fig id="fig5" position="float">
     <label>Figure 5</label>
     <caption>
      <title>Source: prepared by the authors.Figure 5. Failure categories.</title>
     </caption>
     <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/1503138-rId18.jpeg?20250411091241" />
    </fig>
    <p>When analyzing the list of failure factors found in the researched articles, it was noted that some of these factors referred to the region where the spin-off is located or to the region’s link with innovation. Thus, the first category, “Scope – innovation ecosystem”, was defined, as can be seen in <xref ref-type="fig" rid="fig5">
      Figure 5
     </xref>.</p>
    <p>The description of characteristics related to how the parent university drives motivation for entrepreneurship was also presented among the failure factors found in the articles analyzed, with this category being called “entrepreneurial culture of the parent university”.</p>
    <p>In several articles researched, factors related to the number of employees and the method of choosing these professionals were found as reasons for the failure of spin-offs. These factors were grouped into a category called “Team”. Failure factors related to spin-off management were also found. These factors highlighted in the researched articles were grouped into another category called “Management”.</p>
    <p>Government support, also present in the list of failure factors identified in the articles researched, was grouped into a category called “Government”. There were many failure factors also related to the market environment in which the spin-off is or should be inserted, indicating a negative influence on the creation and maintenance of this type of organization. These factors were grouped into the category called “Market”.</p>
    <p>Some articles also pointed out failure factors related to the lack of a consistent “Institutional Policy” on the part of the mother university, with clear and specific rules that provide motivation for its researchers. Another category, called “Portfolio”, was created based on failure factors that linked the failure of spin-offs to the lack of development of diverse technologies by these companies.</p>
    <p>The lack of adequate infrastructure, as well as lack of investment, were also presented in several researched articles and considered as factors of failure. These factors were grouped into a category called “Resources”.</p>
    <p>Finally, the “Parent University” category was created to encompass the various failure factors that dealt with aspects directly related to the parent university and that affect the creation and maintenance of university spin-offs. Highlights include the lack of support from the parent university in providing adequate infrastructure and the lack of a relationship with the university spin-off.</p>
    <p>Phase 4: Category Group</p>
    <p>
     <xref ref-type="table" rid="table2">
      Table 2
     </xref> shows the number of factors related to each category. The same article may have cited several failure factors that were classified as belonging to a given category, as shown in <xref ref-type="table" rid="table2">
      Table 2
     </xref>.</p>
    <table-wrap id="table2">
     <label>
      <xref ref-type="table" rid="table2">
       Table 2
      </xref></label>
     <caption>
      <title>
       <xref ref-type="bibr" rid="scirp.141880-"></xref>Table 2. Number of factors cited in their categories.</title>
     </caption>
     <table class="MsoTableGrid custom-table" border="0" cellspacing="0" cellpadding="0"> 
      <tr> 
       <td class="custom-bottom-td aleft" width="57.27%"><p style="text-align:left">Category</p></td> 
       <td class="custom-bottom-td aleft" width="42.73%"><p style="text-align:left">Number of factors</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="57.27%"><p style="text-align:left">Resources</p></td> 
       <td class="custom-top-td aleft" width="42.73%"><p style="text-align:left">27</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="57.27%"><p style="text-align:left">Management</p></td> 
       <td class="aleft" width="42.73%"><p style="text-align:left">20</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="57.27%"><p style="text-align:left">Market</p></td> 
       <td class="aleft" width="42.73%"><p style="text-align:left">19</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="57.27%"><p style="text-align:left">Entrepreneurial culture</p></td> 
       <td class="aleft" width="42.73%"><p style="text-align:left">16</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="57.27%"><p style="text-align:left">Mother university</p></td> 
       <td class="aleft" width="42.73%"><p style="text-align:left">14</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="57.27%"><p style="text-align:left">Institutional policy</p></td> 
       <td class="aleft" width="42.73%"><p style="text-align:left">9</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="57.27%"><p style="text-align:left">Team </p></td> 
       <td class="aleft" width="42.73%"><p style="text-align:left">8</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="57.27%"><p style="text-align:left">Scope - Innovation Ecosystem</p></td> 
       <td class="aleft" width="42.73%"><p style="text-align:left">6</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="57.27%"><p style="text-align:left">Government</p></td> 
       <td class="aleft" width="42.73%"><p style="text-align:left">5</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="57.27%"><p style="text-align:left">Portfolio</p></td> 
       <td class="aleft" width="42.73%"><p style="text-align:left">3</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="57.27%"><p style="text-align:left">Total</p></td> 
       <td class="aleft" width="42.73%"><p style="text-align:left">127</p></td> 
      </tr> 
     </table>
    </table-wrap>
    <p>Source: Authors.</p>
    <p>Considering the failure factors cited in the articles, the category “resources” stood out, which includes infrastructure and financial resources. Next came the categories management, market, entrepreneurial culture and parent university with the most significant results.</p>
    <p>
     <xref ref-type="table" rid="table3">
      Table 3
     </xref> presents the classification of failure factors in each category, as well as the authors who cited each failure factor. Each category (Cat.) is represented by an equivalent numbering as shown in <xref ref-type="fig" rid="fig5">
      Figure 5
     </xref>: 1 Scope - Innovation Ecosystem, 2 Entrepreneurial culture at the mother university, 3 Team, 4 Management, 5 Government, 6 Market, 7 Institutional policy, 8 Resources, 9 Portfolio, 10 Mother university.</p>
    <table-wrap id="table3">
     <label>
      <xref ref-type="table" rid="table3">
       Table 3
      </xref></label>
     <caption>
      <title>
       <xref ref-type="bibr" rid="scirp.141880-"></xref>Table 3. Factors classified by category.</title>
     </caption>
     <table class="MsoTableGrid custom-table" border="0" cellspacing="0" cellpadding="0"> 
      <tr> 
       <td class="custom-bottom-td aleft" width="5.08%"><p style="text-align:left">Cat.</p></td> 
       <td class="custom-bottom-td aleft" width="24.85%"><p style="text-align:left">Failure factors</p></td> 
       <td class="custom-bottom-td aleft" width="19.95%"><p style="text-align:left">Authors</p></td> 
       <td class="custom-bottom-td aleft" width="4.73%"><p style="text-align:left">Cat.</p></td> 
       <td class="custom-bottom-td aleft" width="25.20%"><p style="text-align:left">Failure factors</p></td> 
       <td class="custom-bottom-td aleft" width="20.19%"><p style="text-align:left">Authors</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="5.08%"><p style="text-align:left">1</p></td> 
       <td class="custom-top-td aleft" width="24.85%"><p style="text-align:left">External features such as regional infrastructure</p></td> 
       <td class="custom-top-td aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-43">
          O’Shea, Chugh and Allen (2008)
         </xref></p></td> 
       <td class="custom-top-td aleft" width="4.73%"><p style="text-align:left">2</p></td> 
       <td class="custom-top-td aleft" width="25.20%"><p style="text-align:left">Lack of market-oriented research institutions</p></td> 
       <td class="custom-top-td aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">1</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Country and region specific differences</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">2</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Lack of best practices for entrepreneurship</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-35">
          Montiel-Campos (2018)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">1</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Being in an environment conducive to entrepreneurship</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-28">
          Lockett et al. (2005)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">2</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Lack of qualified professionals at the university for guidance</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-4">
          Botelho and Almeida (2011)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">1</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Evolution of the ecosystem in the spin-off region</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-1">
          Bagchi-Sen, Baines and Lawton Smith (2020)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">2</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Lack of a legal arrangement conducive to innovation</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-23">
          Hayter, Lubynsky and Maroulis (2017)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">1</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Lack of external support (where it is located)</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-22">
          Harrison and Leitch (2010)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">2</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Lack of an “entrepreneurial culture”</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-23">
          Hayter, Lubynsky and Maroulis (2017)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">1</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Infrastructure (environments conducive to innovation)</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-21">
          Gómez Gras et al. (2008)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">2</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Academic system</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">2</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Entrepreneurial competence</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-3">
          Bolzani, Rasmussen and Fini (2020)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">3</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Human capital</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-21">
          Gómez Gras et al. (2008)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">2</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Weak entrepreneurial culture and infrastructure</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-4">
          Botelho and Almeida (2011)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">3</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Homogeneous team composition</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-51">
          Santos and Teixeira (2012)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">2</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">University culture not conducive to technology transfer, culture clash between industry and academia</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón‑Hernández, Jiménez‑Zapata and Serna‑Gomez (2020)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">3</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Recruitment of personnel with connection to the market</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-60">
          Wennberg, Wiklund and Wright (2011)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">2</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Conceptual divergences,</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-12">
          Czakon, Jedynak and Konopka-Cupiał (2022)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">3</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Employee engagement</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-23">
          Hayter, Lubynsky and Maroulis (2017)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">2</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Involvement in entrepreneurial activity (studies of individual characteristics)</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-43">
          O’Shea, Chugh and Allen (2008)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">3</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Diverse team</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-28">
          Lockett et al. (2005)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">2</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Institutional and cultural studies</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-43">
          O’Shea, Chugh and Allen (2008)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">3</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Very young team</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-16">
          Fiorentino et al. (2022)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">2</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Existence of myths and misconceptions about academic entrepreneurship</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón‑Hernández, Jiménez‑Zapata and Serna‑Gomez (2020)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">3</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Delayed Human Resource Management</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">2</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Lack of a model to stimulate entrepreneurial culture</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-46">
          Oliveira (2015)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">3</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Human capital limitations</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-23">
          Hayter, Lubynsky and Maroulis (2017)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">2</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Lack of entrepreneurial skills, knowledge and</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Internal capabilities</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-20">
          Freitas et al. (2012)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">2</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Lack of training in entrepreneurship</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-42">
          Neves and Franco (2016)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Organizational characteristics Bureaucracy</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Internal governance conflicts</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref>; <xref ref-type="bibr" rid="scirp.141880-40">
          Ndonzuau, Pirnay and Surlemont (2002)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Conflict of interest</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref>; <xref ref-type="bibr" rid="scirp.141880-40">
          Ndonzuau, Pirnay and Surlemont (2002)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Difficulty in the project of enterprise</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-40">
          Ndonzuau, Pirnay and Surlemont (2002)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Insufficient political support</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Delayed management style</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Lack of public support</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-26">
          Kulkov et al. (2019)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Irrational management structure</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Lack of public policy</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-28">
          Lockett et al. (2005)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Lack of professional management</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-28">
          Lockett et al. (2005)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Vague beneficial interests</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Lack of growth</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-61">
          Yagüe-Perales and March-Chordà (2012)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Government support</p><p style="text-align:left"></p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-62">
          Zhang (2009)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Delayed Operation Philosophy</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Market-seeking alliances reduce the probability of failure, while technology-seeking alliances increase the probability of failure.</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-7">
          Bruneel et al. (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Lack of economies of scale</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Trade barriers</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-26">
          Kulkov et al. (2019)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Lack of legitimacy with companies and universities</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-19">
          François and Philippart (2019)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Market demand</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-56">
          van Geenhuizen and Soetanto (2009)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Project management</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-51">
          Santos and Teixeira (2012)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Being away from the market</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-34">
          Modina et al. (2024)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Ambiguous corporate governance</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Lack of applicability of knowledge</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Individualism of entrepreneurs/researchers</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-42">
          Neves and Franco (2016)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Lack of application of knowledge</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-42">
          Neves and Franco (2016)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Business mismanagement</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-40">
          Ndonzuau, Pirnay and Surlemont (2002)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Lack of trust from future customers</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-51">
          Santos and Teixeira (2012)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Unable to separate spin-off and parent university</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-40">
          Ndonzuau, Pirnay and Surlemont (2002)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Adaptation to the market</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-51">
          Santos and Teixeira (2012)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Business-oriented management concerns</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Negative link between the inventor’s ongoing interaction with the university and with the spin-off</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-29">
          Laage-Hellman et al. (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Internal governance issues</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Suitable business model</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-31">
          Martínez-Martínez et al. (2021)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Management overload</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-56">
          van Geenhuizen and Soetanto (2009)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Little experience of entrepreneurs</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-51">
          Santos and Teixeira (2012)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Lack of external relationships</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-29">
          Laage-Hellman et al. (2020)
         </xref>; <xref ref-type="bibr" rid="scirp.141880-22">
          Harrison and Leitch (2010)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">7</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Legal restrictions on spin-off creation</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón‑Hernández, Jiménez‑Zapata and Serna‑Gomez (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">lack of market selectivity - Business model analysis</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-4">
          Botelho and Almeida (2011)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">7</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Support programs</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-56">
          van Geenhuizen and Soetanto (2009)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Weak collaboration between universities and industry.</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-35">
          Montiel-Campos (2018)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Insufficient financial support</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Degree of technology maturity</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-62">
          Zhang (2009)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Venture capital</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-61">
          Yagüe-Perales and March-Chordà (2012)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Negative impact - trying to over-anticipate customer expectations: proactive customer intelligence generation (PCIG)</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-8">
          Buratti, Profumo and Persico (2021)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">High cost to generate spin-off </p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-44">
          Odei and Stejskal (2018)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Technological ties maintained by academic entrepreneurs committed to serving the technological development of parent universities have a negative impact on the market performance of spin-offs</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-3">
          Bolzani, Rasmussen and Fini (2020)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Difficulty in obtaining financial support due to bureaucracy</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Support in the development of business plans offered by public institutions</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-12">
          Czakon, Jedynak and Konopka-Cupiał (2022)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Lack of venture capital</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Contact networks</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-20">
          Freitas et al. (2012)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Lack of resources</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-23">
          Hayter, Lubynsky and Maroulis (2017)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">7</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Lack of monetary incentives for researchers</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-37">
          Muscio, Quaglione and Ramaciotti (2016)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Lack of resources</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-42">
          Neves and Franco (2016)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">7</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Lack of institutional policy</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-37">
          Muscio, Quaglione and Ramaciotti (2016)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Lack of financial resources</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-57">
          Vega-Gómez, González and Pérez-Mayo (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">7</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Lack of policy</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-28">
          Lockett et al. (2005)
         </xref>; <xref ref-type="bibr" rid="scirp.141880-15">
          Fini et al. (2017)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Lack of financial resources</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-26">
          Kulkov et al. (2019)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">7</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Internal regulations for the creation of SPIN-OFFS</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-37">
          Muscio, Quaglione and Ramaciotti (2016)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Infrastructure</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-23">
          Hayter, Lubynsky and Maroulis (2017)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">7</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Lack of policy that motivates the creation of spin-offs</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-35">
          Montiel-Campos (2018)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Infrastructure</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-56">
          van Geenhuizen and Soetanto (2009)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">7</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Spin-off policies that offer little support.</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-4">
          Botelho and Almeida (2011)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Risk of investing in SPIN-offs</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-36">
          Munari and Toschi (2011)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">7</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Few incentives</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón‑Hernández, Jiménez‑Zapata and Serna‑Gomez (2020)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Inadequate type of financing</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-31">
          Martínez-Martínez et al. (2021)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Difficulty accessing tangible resources such as structure and machinery</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-40">
          Ndonzuau, Pirnay and Surlemont (2002)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">9</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Diversity of product and service categories offered by spin-offs.</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-2">
          Baines and Smith (2019)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Difficulty in raising funds</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-15">
          Fini et al. (2017)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Support from the parent university</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-56">
          van Geenhuizen and Soetanto (2009)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Shortage of resources for investment</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-51">
          Santos and Teixeira (2012)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Links with parent universities can also introduce liabilities that limit their market performance.</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-3">
          Bolzani, Rasmussen and Fini (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Structure of resources and capabilities that the parent organization provides</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-61">
          Yagüe-Perales and March-Chordà (2012)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Lack of intervention by the university management team</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-19">
          François and Philippart (2019)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Lack of access to tangible resources</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-28">
          Lockett et al. (2005)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Lack of infrastructural support.</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Lack of facilities</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-63">
          Zhou et al. (2011)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Lack of internal support (university)</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-22">
          Harrison and Leitch (2010)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Lack of intangibles</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-28">
          Lockett et al. (2005)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Lack of internal relationship with the parent university</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-29">
          Laage-Hellman et al. (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Lack of resources</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-40">
          Ndonzuau, Pirnay and Surlemont (2002)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Lack of support from the home institution</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-51">
          Santos and Teixeira (2012)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Insufficient investment</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-35">
          Montiel-Campos (2018)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">The parent university was not properly asked to rescue a process that was failing.</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-19">
          François and Philippart (2019)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Non-Availability of Resources</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-40">
          Ndonzuau, Pirnay and Surlemont (2002)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Minimum university-business-state integration</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón‑Hernández, Jiménez‑Zapata and Serna‑Gomez (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Prejudice on the part of venture capital firms against investing in spin-offs.</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-36">
          Munari and Toschi (2011)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Support measures provided by universities</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-21">
          Gómez Gras et al. (2008)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Cash flow problems</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-56">
          van Geenhuizen and Soetanto (2009)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">The attributes of universities such as human capital, commercial resources and institutional activities</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-43">
          O’Shea, Chugh and Allen (2008)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Resources and capabilities of the ttos ability to seek external financing</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-21">
          Gómez Gras et al. (2008)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Researchers ignore the institution’s formal process</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-15">
          Fini et al. (2017)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Financial issues to transform the invention into a developed technological product</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-40">
          Ndonzuau, Pirnay and Surlemont (2002)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Accommodation problems</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-56">
          van Geenhuizen and Soetanto (2009)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">9</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Technology stock - capacity to generate new technological innovations</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-21">
          Gómez Gras et al. (2008)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left">Relationships that must be established between the spin-off company and its parent university</p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-40">
          Ndonzuau, Pirnay and Surlemont (2002)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="5.08%"><p style="text-align:left">9</p></td> 
       <td class="aleft" width="24.85%"><p style="text-align:left">Patenting</p></td> 
       <td class="aleft" width="19.95%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-61">
          Yagüe-Perales and March-Chordà (2012)
         </xref></p></td> 
       <td class="aleft" width="4.73%"><p style="text-align:left"></p></td> 
       <td class="aleft" width="25.20%"><p style="text-align:left"></p></td> 
       <td class="aleft" width="20.19%"><p style="text-align:left"></p></td> 
      </tr> 
     </table>
    </table-wrap>
    <p>Source: authors.</p>
    <p>Within the scope of this article, understanding how success factors were classified into categories, as well as the number of de factors in times each category was cited, allows us to move on to the next phases and identify the tendency for categories to influence the failure of university spin-offs.</p>
   </sec>
   <sec id="s4_2">
    <title>4.2. Success Factors</title>
    <p>To present the success factors found in the analyzed articles, the methodology in <xref ref-type="fig" rid="fig4">
      Figure 4
     </xref> will be used.</p>
    <p>Phase 1 - Reading and analysis of articles</p>
    <p>In this first phase, 33 selected articles were read and analyzed. In these articles, the aspects that motivate and facilitate the creation and maintenance of university or academic spin-offs were selected. These aspects were considered success factors for this type of organization. These aspects were extracted from concepts considered motivating and facilitating the development of spinoffs according to the authors’ concepts listed in <xref ref-type="table" rid="table4">
      Table 4
     </xref>.</p>
    <p>Phase 2 - List of success factors</p>
    <p>For this phase, all the aspects researched in the articles and considered success factors were gathered in a table. In this case, 130 success factors were found, which, according to the articles analyzed, favor the creation and maintenance of university or academic spin-offs. <xref ref-type="table" rid="table4">
      Table 4
     </xref> lists the 130 success factors found, as well as the authors of the articles in which the factors were cited.</p>
    <table-wrap id="table4">
     <label>
      <xref ref-type="table" rid="table4">
       Table 4
      </xref></label>
     <caption>
      <title>
       <xref ref-type="bibr" rid="scirp.141880-"></xref>Table 4. List of success factors.</title>
     </caption>
     <table class="MsoTableGrid custom-table" border="0" cellspacing="0" cellpadding="0"> 
      <tr> 
       <td class="custom-bottom-td aleft" width="28.18%"><p style="text-align:left">Success factors</p></td> 
       <td class="custom-bottom-td aleft" width="21.50%"><p style="text-align:left">Authors</p></td> 
       <td class="custom-bottom-td aleft" width="28.27%"><p style="text-align:left">Success factors</p></td> 
       <td class="custom-bottom-td aleft" width="22.06%"><p style="text-align:left">Authors</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="28.18%"><p style="text-align:left">Venture capital support</p></td> 
       <td class="custom-top-td aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-7">
          Bruneel et al. (2020)
         </xref></p></td> 
       <td class="custom-top-td aleft" width="28.27%"><p style="text-align:left">Human capital</p></td> 
       <td class="custom-top-td aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-46">
          Oliveira (2015)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Venture capital</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-31">
          Martínez-Martínez et al. (2021)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Team formation with students of different ages, young and senior</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-16">
          Fiorentino et al. (2022)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Venture capital investors</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-7">
          Bruneel et al. (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Management teams</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Financial support</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-51">
          Santos and Teixeira (2012)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Qualified staff</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-2">
          Baines and Smith (2019)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Financial support from the public, universities and other sources</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-44">
          Odei and Stejskal (2018)
         </xref> </p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Recruit high quality staff</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-38">
          Mustar et al. (2006)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Public support/funding</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-26">
          Kulkov et al. (2019)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Member selection</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-7">
          Bruneel et al. (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Financing of new ventures</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-32">
          Mathisen and Rasmussen (2019)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Economic environment</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-55">
          Torres and Invernizzi (2022)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Financing and investment</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-2">
          Baines and Smith (2019)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Favorable market conditions</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-35">
          Montiel-Campos (2018)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Financing for the creation of the Spin-off</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-31">
          Martínez-Martínez et al. (2021)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Regional and national contexts</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Financial resources</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-46">
          Oliveira (2015)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Economic factors</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-16">
          Fiorentino et al. (2022)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Financial resources</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-38">
          Mustar et al. (2006)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Innovation ecosystem</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-26">
          Kulkov et al. (2019)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Research funding</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-44">
          Odei and Stejskal (2018)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Innovation ecosystem</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-35">
          Montiel-Campos (2018)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Public funding for research</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-31">
          Martínez-Martínez et al. (2021)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Existence of an innovation ecosystem in the region</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-38">
          Mustar et al. (2006)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Have working capital</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-51">
          Santos and Teixeira (2012)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Support infrastructures, such as science parks, incubators, incentive support</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-44">
          Odei and Stejskal (2018)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Development of an organizational culture</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-12">
          Czakon, Jedynak and Konopka-Cupiał (2022)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Policy</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-46">
          Oliveira (2015)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Culture</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-46">
          Oliveira (2015)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Entrepreneurial skills</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-54">
          Thomas et al. (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Organizational culture</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón‑Hernández, Jiménez‑Zapata and Serna‑Gomez (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Favorable climate for the development of entrepreneurship</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-12">
          Czakon, Jedynak and Konopka-Cupiał (2022)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Sociocultural dimension</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-55">
          Torres and Invernizzi (2022)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Entrepreneurial behavior</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-52">
          Teppo (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Full-time dedicated academic</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-1">
          Bagchi-Sen, Baines and Lawton Smith (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Management Skills Needed by Academic Entrepreneurs</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-2">
          Baines and Smith (2019)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Diverse team</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-49">
          Prencipe et al. (2023)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Create a business environment where all activities aimed at creating value for the customer are coordinated and collaboration between the different areas is developed</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-8">
          Buratti, Profumo and Persico (2021)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Develop a viable business model</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-2">
          Baines and Smith (2019)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Market adaptation</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-51">
          Santos and Teixeira (2012)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Existence of business model and growth model</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-31">
          Martínez-Martínez et al. (2021)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Technology-market matching capability</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-54">
          Thomas et al. (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Models as drivers</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón‑Hernández, Jiménez‑Zapata and Serna‑Gomez (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Ability to interpret the Business environment</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón‑Hernández, Jiménez‑Zapata and Serna‑Gomez (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Competitiveness</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-25">
          Korpysa (2018)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Market understanding</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón‑Hernández, Jiménez‑Zapata and Serna‑Gomez (2020
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Dynamic sensing and modeling capabilities</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-54">
          Thomas et al. (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Focus on market characteristics</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-38">
          Mustar et al. (2006)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Dissemination, integration and interfunctional coordination</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-8">
          Buratti, Profumo and Persico (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Market orientation</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-8">
          Buratti, Profumo and Persico (2021)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Goal setting</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-2">
          Baines and Smith (2019)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Know the competition</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-25">
          Korpysa (2018)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Company strategies and objectives and structures</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Technological surveillance</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón‑Hernández, Jiménez‑Zapata and Serna‑Gomez (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Internal factors of a company</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Business environment</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-55">
          Torres and Invernizzi (2022)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Focus on integration between different functions</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-8">
          Buratti, Profumo and Persico (2021)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Management capacity and market orientation of its managers</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-57">
          Vega-Gómez, González and Pérez-Mayo (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Organizational characteristics</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón‑Hernández, Jiménez‑Zapata and Serna‑Gomez (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Anticipating customer needs - developing new value propositions capable of satisfying the needs of potential customers</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-8">
          Buratti, Profumo and Persico (2021)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Hierarchy</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón‑Hernández, Jiménez‑Zapata and Serna‑Gomez (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Understanding customer needs</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-2">
          Baines and Smith (2019)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Composition and characteristics of the foundation</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Knowing the needs of customers</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-25">
          Korpysa (2018)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Initial competence</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Responsive customer intelligence generation</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-8">
          Buratti, Profumo and Persico (2021)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Organization reputation</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-38">
          Mustar et al. (2006)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Alliance in the Market</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-7">
          Bruneel et al. (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Internal interrelationships (new inventions) to enhance the creation of spin-offs</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón‑Hernández, Jiménez‑Zapata and Serna‑Gomez (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Proximity to the commercial world</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-34">
          Modina et al. (2024)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Assessment of technology maturity before launch</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-54">
          Thomas et al. (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Relationship with the market</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-46">
          Oliveira (2015)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Nature of bonds or ties</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-55">
          Torres and Invernizzi (2022)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">External interrelations (relationship with the market) to enhance the creation of spin-offs</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-29">
          Laage-Hellman et al. (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Technology Transfer Recipient Participation</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-47">
          Pimenta (2017)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Relationship with industry</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-55">
          Torres and Invernizzi (2022)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Collaborations with external partners and gaining access to external technological knowledge and expertise</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-2">
          Baines and Smith (2019)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Number of registered patents and investment</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-47">
          Pimenta (2017)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Building connections outside the university</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón‑Hernández, Jiménez‑Zapata and Serna‑Gomez (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Patenting</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-31">
          Martínez-Martínez et al. (2021)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Creation of formal cooperation procedures</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-12">
          Czakon, Jedynak and Konopka-Cupiał (2022)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Patents</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-57">
          Vega-Gómez, González and Pérez-Mayo (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Development of cooperation networks</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-12">
          Czakon, Jedynak and Konopka-Cupiał (2022)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Protect the invention</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-54">
          Thomas et al. (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Partners</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-51">
          Santos and Teixeira (2012)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Unconventional solutions to solve problems</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-59">
          Vutsova and Arabadzhieva (2021)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Prominent partners</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-7">
          Bruneel et al. (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Innovation policies</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-34">
          Modina et al. (2024)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Potential Business Partners</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-29">
          Laage-Hellman et al. (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Legal framework and regulatory structure</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-55">
          Torres and Invernizzi (2022)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Relationship with other partners - creating collaborative relationships</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-29">
          Laage-Hellman et al. (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">University policy</p><p style="text-align:left"></p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón‑Hernández, Jiménez‑Zapata and Serna‑Gomez (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Relations with the innovation ecosystem</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-34">
          Modina et al. (2024)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Property rights for spin-off</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-26">
          Kulkov et al. (2019)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Type of interaction in the ecosystem and relationship with the industry</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-55">
          Torres and Invernizzi (2022)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Understanding the concept of spin-off</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón‑Hernández, Jiménez‑Zapata and Serna‑Gomez (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Autonomy and predisposition for innovation and trust</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón‑Hernández, Jiménez‑Zapata and Serna‑Gomez (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Mechanisms in universities to avoid conflicts of interest</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-12">
          Czakon, Jedynak &amp; Gabriela Konopka-Cupiał (2022)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Ability to innovate</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-32">
          Mathisen and Rasmussen (2019)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Models for building strategies, processes and institutional mechanisms facilitating the generation of spin-offs.</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón‑Hernández, Jiménez‑Zapata and Serna‑Gomez (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Entrepreneurial capacity</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-54">
          Thomas et al. (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">University technology transfer support systems need to be effective</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-2">
          Baines and Smith (2019)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Founding of the spin-off by the entrepreneurial scientist</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-54">
          Thomas et al. (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Internal mechanisms to support academics to commercialize research results</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-44">
          Odei and Stejskal (2018)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Ability to take advantage of opportunities.</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-54">
          Thomas et al. (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Incentives for business creators</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón-Hernández, Jiménez-Zapata and Serna-Gomez (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">New inventions</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-29">
          Laage-Hellman et al. (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Type of support received</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-55">
          Torres and Invernizzi (2022)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Adequate support, training and infrastructure at universities</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-14">
          Fernández-Lopez et al. (2018)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Improving studies by Technology Transfer offices</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-35">
          Montiel-Campos (2018)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Availability of universities to provide support mechanisms on or around campus</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-44">
          Odei and Stejskal (2018)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Improve the skills of professionals at university who are experts in moving from university to industry</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-26">
          Kulkov et al. (2019)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Receive bureaucratic support from the university</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-57">
          Vega-Gómez, González and Pérez-Mayo (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Parent institution can also be a source of network connections</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-38">
          Mustare et al. (2006)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Receive training support from the university</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-57">
          Vega-Gómez, González and Pérez-Mayo (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Role of research excellence</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-1">
          Bagchi-Sen, Baines and Lawton Smith (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">University to have resources</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-35">
          Montiel-Campos (2018)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Focus on disseminating knowledge</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-8">
          Buratti, Profumo and Persico (2021)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Attract and mentor the founding team</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-54">
          Thomas et al. (2020)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Proposal and significance for university</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón-Hernández, Jiménez-Zapata and Serna-Gomez (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Support from the board of directors-highest level of decision-making body</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-58">
          Veltri, Puntillo and Pierri (2022)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Third mission recognition</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón-Hernández, Jiménez-Zapata and Serna-Gomez (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Strategic support from the university</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-38">
          Mustar et al. (2006)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Encouragement from the university to undertake</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-35">
          Montiel-Campos (2018)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Supporting institution</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-46">
          Oliveira (2015)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Relationship and trust in the parent university</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-29">
          Laage-Hellman et al. (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="28.18%"><p style="text-align:left">Provision of support by the parent university</p></td> 
       <td class="aleft" width="21.50%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-12">
          Czakon, Jedynak and Konopka-Cupiał (2022)
         </xref></p></td> 
       <td class="aleft" width="28.27%"><p style="text-align:left">Academic culture</p></td> 
       <td class="aleft" width="22.06%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-3">
          Bolzani, Rasmussen and Fini (2020
         </xref></p></td> 
      </tr> 
     </table>
    </table-wrap>
    <p>Source: the authors.</p>
    <p>Phase 3 - Definition of categories</p>
    <p>In the articles researched, 130 factors were found that can lead a spin-off to sucess. These factors were grouped into categories. Each of these categories grouped a set of sucess factors. Ten categories were classified as shown in <xref ref-type="fig" rid="fig6">
      Figure 6
     </xref>.</p>
    <fig id="fig6" position="float">
     <label>Figure 6</label>
     <caption>
      <title>Source: authors.Figure 6. Success factor categories.</title>
     </caption>
     <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/1503138-rId19.jpeg?20250411091241" />
    </fig>
    <p>One of the factors identified among the articles analyzed is related to issues related to the finances of spin-offs. According to the studies read, the financial issue was identified as essential for the success in the creation and maintenance of university or academic spin-offs. Thus, this factor gave rise to a category called “Financial Support”.</p>
    <p>Another fact indicated as being important for the success of spin-offs is related to the way the university deals with issues related to entrepreneurship internally and in its surroundings. These factors were grouped in the category called “Organizational Culture”.</p>
    <p>The studies analyzed also pointed out some issues related to the components of the university spin-off. These success factors were grouped into the category called “Team”. Another success factor found is related to the environment in which the university spin-off is inserted, involving ecosystem and regionalization. Thus, the category “Environmental factors” was created.</p>
    <p>The category called “Management” was created because many of the articles analyzed brought together relevant success factors in the way the university spin-off is managed by its leaders. The category “Market” was created because many articles cited aspects of success that the university spin-off must consider in its insertion and maintenance in the market of which it will be a part.</p>
    <p>Success factors that refer to the existence of relationship networks and contacts that were identified in the studies were associated with the category called “Partnerships”. The characteristics of success of the university spin-off found in the research and related to entrepreneurship were grouped into a category called “Entrepreneurial profile”.</p>
    <p>A set of factors found in the studies analyzed described the “Institutional policy” at the parent university as a relevant aspect for the creation of the university spin-off to be successful. Furthermore, several other success factors related to the institution that originated the university spin-off were cited. These factors were grouped in the category “Mother University”.</p>
    <p>Phase 4 - Category group</p>
    <p>The information in <xref ref-type="table" rid="table5">
      Table 5
     </xref> shows the number of times each success factor was cited in the articles analyzed and its corresponding category. The same article may have cited several success factors that were classified as belonging to a given category.</p>
    <table-wrap id="table5">
     <label>
      <xref ref-type="table" rid="table5">
       Table 5
      </xref></label>
     <caption>
      <title>
       <xref ref-type="bibr" rid="scirp.141880-"></xref>Table 5. Number of factors cited in the articles por categories.</title>
     </caption>
     <table class="MsoTableGrid custom-table" border="0" cellspacing="0" cellpadding="0"> 
      <tr> 
       <td class="custom-bottom-td aleft" width="33.98%"><p style="text-align:left">Category</p></td> 
       <td class="custom-bottom-td aleft" width="28.31%"><p style="text-align:left">Number of factors</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="33.98%"><p style="text-align:left">Management</p></td> 
       <td class="custom-top-td aleft" width="28.31%"><p style="text-align:left">24</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="33.98%"><p style="text-align:left">Parent university</p></td> 
       <td class="aleft" width="28.31%"><p style="text-align:left">21</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="33.98%"><p style="text-align:left">Market</p></td> 
       <td class="aleft" width="28.31%"><p style="text-align:left">19</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="33.98%"><p style="text-align:left">Financial support</p></td> 
       <td class="aleft" width="28.31%"><p style="text-align:left">14</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="33.98%"><p style="text-align:left">Entrepreneurial profile</p></td> 
       <td class="aleft" width="28.31%"><p style="text-align:left">11</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="33.98%"><p style="text-align:left">Partnerships</p></td> 
       <td class="aleft" width="28.31%"><p style="text-align:left">10</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="33.98%"><p style="text-align:left">Institutional policy</p></td> 
       <td class="aleft" width="28.31%"><p style="text-align:left">10</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="33.98%"><p style="text-align:left">Environmental factors</p></td> 
       <td class="aleft" width="28.31%"><p style="text-align:left">9</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="33.98%"><p style="text-align:left">Team</p></td> 
       <td class="aleft" width="28.31%"><p style="text-align:left">8</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="33.98%"><p style="text-align:left">Organizational Culture</p></td> 
       <td class="aleft" width="28.31%"><p style="text-align:left">4</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="33.98%"><p style="text-align:left">Total</p></td> 
       <td class="aleft" width="28.31%"><p style="text-align:left">130</p></td> 
      </tr> 
     </table>
    </table-wrap>
    <p>Looking at <xref ref-type="table" rid="table5">
      Table 5
     </xref>, we can see that the category with the highest number of success factors is “Management” with 24 mentions, followed by the parent university, which appears 21 times, and then by the market, mentioned 19 times.</p>
    <p>
     <xref ref-type="table" rid="table6">
      Table 6
     </xref> presents the categories, their respective success factors and the authors of the articles that cite each factor.</p>
    <table-wrap id="table6">
     <label>
      <xref ref-type="table" rid="table6">
       Table 6
      </xref></label>
     <caption>
      <title>
       <xref ref-type="bibr" rid="scirp.141880-"></xref>Table 6. Factors classified by category.</title>
     </caption>
     <table class="MsoTableGrid custom-table" border="0" cellspacing="0" cellpadding="0"> 
      <tr> 
       <td class="custom-bottom-td aleft" width="4.94%"><p style="text-align:left">Cat.</p></td> 
       <td class="custom-bottom-td aleft" width="23.01%"><p style="text-align:left">Success Factors</p></td> 
       <td class="custom-bottom-td aleft" width="20.27%"><p style="text-align:left">Authors</p></td> 
       <td class="custom-bottom-td aleft" width="4.79%"><p style="text-align:left">Cat.</p></td> 
       <td class="custom-bottom-td aleft" width="27.88%"><p style="text-align:left">Success Factors</p></td> 
       <td class="custom-bottom-td aleft" width="19.11%"><p style="text-align:left">Authors</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="4.94%"><p style="text-align:left">1</p></td> 
       <td class="custom-top-td aleft" width="23.01%"><p style="text-align:left">Venture capital support</p></td> 
       <td class="custom-top-td aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-7">
          Bruneel et al. (2020)
         </xref></p></td> 
       <td class="custom-top-td aleft" width="4.79%"><p style="text-align:left">3</p></td> 
       <td class="custom-top-td aleft" width="27.88%"><p style="text-align:left">Team formation with students of different ages, young and sênior</p></td> 
       <td class="custom-top-td aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-16">
          Fiorentino et al. (2022)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">1</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Venture capital</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-31">
          Martínez-Martínez et al. (2021)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">3</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Human capital</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-46">
          Oliveira (2015)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">1</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Venture capital investors</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-7">
          Bruneel et al. (2020)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">3</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Qualified staff</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-2">
          Baines and Smith (2019)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">1</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Financial support</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-51">
          Santos and Teixeira (2012)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">3</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Recruit high quality staff</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-38">
          Mustar et al. (2006)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">1</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Financial support from the public, universities and other sources</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-44">
          Odei and Stejskal (2018)
         </xref> </p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">3</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Member selection</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-7">
          Bruneel et al. (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">1</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Public support/funding</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-26">
          Kulkov et al. (2019)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Economic environment</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-55">
          Torres and Invernizzi (2022)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">1</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Financing of new ventures</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-32">
          Mathisen and Rasmussen (2019)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Favorable market conditions</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-35">
          Montiel-Campos (2018)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">1</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Financing and investment</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-2">
          Baines and Smith (2019)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Regional and national contexts</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">1</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Financing for the creation of the Spin-off</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-31">
          Martínez-Martínez et al. (2021)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Economic factors</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-16">
          Fiorentino et al. (2022)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">1</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Financial resources</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-46">
          Oliveira (2015)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Innovation ecosystem</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-26">
          Kulkov et al. (2019)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">1</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Financial resources</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-38">
          Mustar et al. (2006)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Innovation ecosystem</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-35">
          Montiel-Campos (2018)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">1</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Research funding</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-44">
          Odei and Stejskal (2018)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Existence of an innovation ecosystem in the region</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-38">
          Mustar et al. (2006)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">1</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Public funding for research</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-31">
          Martínez-Martínez et al. (2021)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Support infrastructures, such as science parks, incubators, incentive support</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-44">
          Odei and Stejskal (2018)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">1</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Have working capital</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-51">
          Santos and Teixeira (2012)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">4</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Policy</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-46">
          Oliveira (2015)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">2</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Development of an organizational culture</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-12">
          Czakon, Jedynak and Konopka-Cupiał (2022)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Develop a viable business model</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-2">
          Baines and Smith (2019)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">2</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Culture</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-46">
          Oliveira (2015)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Entrepreneurial skills</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-54">
          Thomas et al. (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">2</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Organizational culture</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón-Hernández, Jiménez-Zapata and Serna-Gomez (2020)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Favorable climate for the development of entrepreneurship</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-12">
          Czakon, Jedynak and Konopka-Cupiał (2022)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">2</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Sociocultural dimension</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-55">
          Torres and Invernizzi (2022)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Business behavior</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-52">
          Teppo (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">3</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Full-time dedicated academic</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-1">
          Bagchi-Sen, Baines and Lawton Smith (2020)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Management Skills Needed by Academic Entrepreneurs</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-2">
          Baines and Smith (2019)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">3</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Diverse team</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-49">
          Prencipe et al. (2023)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Existence of business model and growth model</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-31">
          Martínez-Martínez et al. (2021)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">3</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Management teams</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Hierarchy</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón-Hernández, Jiménez-Zapata and Serna-Gomez (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Organizational characteristics</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón-Hernández, Jiménez-Zapata and Serna-Gomez (2020)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Ability to interpret the Business environment</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón-Hernández, Jiménez-Zapata and Serna-Gomez (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Models as drivers</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón-Hernández, Jiménez-Zapata and Serna-Gomez (2020)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Market understanding</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón-Hernández, Jiménez-Zapata and Serna-Gomez (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Competitiveness</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-25">
          Korpysa (2018)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Focus on market characteristics</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-38">
          Mustar et al. (2006)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Dynamic sensing and modeling capabilities</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-54">
          Thomas et al. (2020)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Know the competition</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-25">
          Korpysa (2018)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Dissemination, integration and interfunctional coordination</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-8">
          Buratti, Profumo and Persico (2021)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Technological surveillance</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón-Hernández, Jiménez-Zapata and Serna-Gomez (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Goal setting</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-2">
          Baines and Smith (2019)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Market orientation</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-8">
          Buratti, Profumo and Persico (2021)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Company strategies and objectives and structures</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Understanding customer needs</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-2">
          Baines and Smith (2019)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Internal factors of a company</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Management capacity and market orientation of its managers</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-57">
          Vega-Gómez, González and Pérez-Mayo (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Internal interrelationships (new inventions) to enhance the creation of spin-offs</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón-Hernández, Jiménez-Zapata and Serna-Gomez (2020)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Anticipating customer needs - developing new value propositions capable of satisfying the needs of potential customers</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-8">
          Buratti, Profumo and Persico (2021)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Create a business environment where all activities aimed at creating value for the customer are coordinated and collaboration between the different areas is developed</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-8">
          Buratti, Profumo and Persico (2021)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Knowing the needs of customers</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-25">
          Korpysa (2018)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Composition and characteristics of the foundation</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Business environment</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-55">
          Torres and Invernizzi (2022)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Initial competence</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-24">
          Hossinger, Chen and Werner (2020)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Responsive customer intelligence generation</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-8">
          Buratti, Profumo and Persico (2021)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Organization reputation</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-38">
          Mustar et al. (2006)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Alliance in the market</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-7">
          Bruneel et al. (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Assessment of technology maturity before launch</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-54">
          Thomas et al. (2020)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">External interrelations (relationship with the market) to enhance the creation of spin-offs</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-29">
          Laage-Hellman et al. (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Nature of bonds or ties</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-55">
          Torres and Invernizzi (2022)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Proximity to the commercial world</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-34">
          Modina et al. (2024)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Technology Transfer Recipient Participation</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-47">
          Pimenta (2017)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Relationship with the Market</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-46">
          Oliveira (2015)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Focus on integration between different functions</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-8">
          Buratti, Profumo and Persico (2021)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Relationship with industry</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-55">
          Torres and Invernizzi (2022)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Market adaptation</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-51">
          Santos and Teixeira (2012)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Entrepreneurial capacity</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-54">
          Thomas et al. (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Technology-market matching capability</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-54">
          Thomas et al. (2020)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">New inventions</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-29">
          Laage-Hellman et al. (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">7</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Partners</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-51">
          Santos and Teixeira (2012)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Number of registered patents and investment</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-47">
          Pimenta (2017)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">7</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Building connections outside the university</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-2">
          Baines and Smith (2019)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Patenting</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-31">
          Martínez-Martínez et al. (2021)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">7</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Creation of formal cooperation procedures</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-12">
          Czakon, Jedynak and Konopka-Cupiał (2022)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Patents</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-57">
          Vega-Gómez, González and Pérez-Mayo (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">7</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Development of cooperation networks</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-12">
          Czakon, Jedynak and Konopka-Cupiał (2022)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Protect the invention</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-54">
          Thomas et al. (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">7</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Relations with the innovation ecosystem</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-34">
          Modina et al. (2024)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Unconventional solutions to solve problems</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-59">
          Vutsova and Arabadzhieva (2021)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">7</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Prominent partners</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-7">
          Bruneel et al. (2020)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">9</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Innovation policies</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-34">
          Modina et al. (2024)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">7</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Potential Business Partners</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-29">
          Laage-Hellman et al. (2020)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">9</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Legal framework and regulatory structure</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-55">
          Torres and Invernizzi (2022)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">7</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Relationship with other partners-creating collaborative relationships</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-29">
          Laage-Hellman et al. (2020)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">9</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">University policy</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón-Hernández, Jiménez-Zapata and Serna-Gomez (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">7</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Collaborations with external partners and gaining access to external technological knowledge and expertise</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-2">
          Baines and Smith (2019)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">9</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Property rights for spin-off</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-26">
          Kulkov et al. (2019)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">7</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Type of interaction in the ecosystem and relationship with the industry</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-55">
          Torres and Invernizzi (2022)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">9</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Understanding the concept of spin-off</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón-Hernández, Jiménez-Zapata and Serna-Gomez (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Autonomy and predisposition for innovation and trust</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón-Hernández, Jiménez-Zapata and Serna-Gomez (2020)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">9</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Mechanisms in universities to avoid conflicts of interest</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-12">
          Czakon, Jedynak &amp; Gabriela Konopka-Cupiał (2022)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Ability to innovate</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-32">
          Mathisen and Rasmussen (2019)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">9</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Models for building strategies, processes and institutional mechanisms facilitating the generation of spin-offs.</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón-Hernández, Jiménez-Zapata and Serna-Gomez (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Founding of the spin-off by the entrepreneurial scientist</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-54">
          Thomas et al. (2020)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">9</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">University technology transfer support systems need to be effective</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-2">
          Baines and Smith (2019)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Ability to take advantage of opportunities.</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-54">
          Thomas et al. (2020)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">9</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Internal mechanisms to support academics to commercialize research results</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-44">
          Odei and Stejskal (2018)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">9</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Incentives for business creators</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón-Hernández, Jiménez-Zapata and Serna-Gomez (2020)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Type of support received</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-55">
          Torres and Invernizzi (2022)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Adequate support, training and infrastructure at universities</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-14">
          Fernández-Lopez et al. (2018)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Improving studies by Technology Transfer offices</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-35">
          Montiel-Campos (2018)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Availability of universities to provide support mechanisms on or around campus</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-44">
          Odei and Stejskal (2018)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Improve the skills of professionals at university who are experts in moving from university to industry</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-26">
          Kulkov et al. (2019)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Receive bureaucratic support from the university</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-57">
          Vega-Gómez, González and Pérez-Mayo (2020)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Parent institution can also be a source of network connections</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-38">
          Mustare et al. (2006)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Receive training support from the university</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-57">
          Vega-Gómez, González and Pérez-Mayo (2020)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Role of research excellence</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-1">
          Bagchi-Sen, Baines and Lawton Smith (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">University to have resources</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-35">
          Montiel-Campos (2018)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Focus on disseminating knowledge</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-8">
          Buratti, Profumo and Persico (2021)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Attract and mentor the founding team</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-54">
          Thomas et al. (2020)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Proposal and significance for university</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón-Hernández, Jiménez-Zapata and Serna-Gomez (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Support from the board of directors - highest level of decision-making body</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-58">
          Veltri, Puntillo and Pierri (2022)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Third mission recognition</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-9">
          Calderón-Hernández, Jiménez-Zapata and Serna-Gomez (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Strategic support from the university</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-38">
          Mustar et al. (2006)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Encouragement from the university to undertake</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-35">
          Montiel-Campos (2018)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Supporting institution</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-46">
          Oliveira (2015)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Relationship and trust in the parent university</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-29">
          Laage-Hellman et al. (2020)
         </xref></p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="4.94%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="23.01%"><p style="text-align:left">Provision of support by the parent university</p></td> 
       <td class="aleft" width="20.27%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-12">
          Czakon, Jedynak and Konopka-Cupiał (2022)
         </xref></p></td> 
       <td class="aleft" width="4.79%"><p style="text-align:left">10</p></td> 
       <td class="aleft" width="27.88%"><p style="text-align:left">Academic culture</p></td> 
       <td class="aleft" width="19.11%"><p style="text-align:left">
         <xref ref-type="bibr" rid="scirp.141880-3">
          Bolzani, Rasmussen and Fini (2020)
         </xref></p></td> 
      </tr> 
     </table>
    </table-wrap>
    <p>Source: the authors.</p>
    <p>Within the scope of this article, understanding how success factors were classified into categories, as well as the number of factors in each category, allows us to move on to the next phases and identify the tendency for categories to influence the success of university spin-offs.</p>
   </sec>
   <sec id="s4_3">
    <title>4.3. Results and Discussion</title>
    <p>The categories were created by grouping similar characteristics found in the articles researched, which we call factors. This was done in relation to both failure factors and success factors.</p>
    <p>The number of failure factors and success factors identified in the articles and categorized are presented in <xref ref-type="table" rid="table7">
      Table 7
     </xref>. The table is organized in descending order, starting with the category containing the most factors and ending with the one with the fewest factors.</p>
    <table-wrap id="table7">
     <label>
      <xref ref-type="table" rid="table7">
       Table 7
      </xref></label>
     <caption>
      <title>
       <xref ref-type="bibr" rid="scirp.141880-"></xref>Table 7. Relationship between categories of failure factors and success factors considering positioning.</title>
     </caption>
     <table class="MsoTableGrid custom-table" border="0" cellspacing="0" cellpadding="0"> 
      <tr> 
       <td class="custom-bottom-td aleft" width="29.92%"><p style="text-align:left">Category Failure factors</p></td> 
       <td class="custom-bottom-td aleft" width="14.52%"><p style="text-align:left">No. of factors </p></td> 
       <td class="custom-bottom-td aleft" width="11.33%"><p style="text-align:left">Position</p></td> 
       <td class="custom-bottom-td aleft" width="29.04%"><p style="text-align:left">Category Success factors</p></td> 
       <td class="custom-bottom-td aleft" width="15.19%"><p style="text-align:left">No. of factors</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="29.92%"><p style="text-align:left">Resource</p></td> 
       <td class="custom-top-td aleft" width="14.52%"><p style="text-align:left">27</p></td> 
       <td class="custom-top-td aleft" width="11.33%"><p style="text-align:left">1˚</p></td> 
       <td class="custom-top-td aleft" width="29.04%"><p style="text-align:left">Management</p></td> 
       <td class="custom-top-td aleft" width="15.19%"><p style="text-align:left">24</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="29.92%"><p style="text-align:left">Management</p></td> 
       <td class="aleft" width="14.52%"><p style="text-align:left">20</p></td> 
       <td class="aleft" width="11.33%"><p style="text-align:left">2˚</p></td> 
       <td class="aleft" width="29.04%"><p style="text-align:left">Mother university</p></td> 
       <td class="aleft" width="15.19%"><p style="text-align:left">21</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="29.92%"><p style="text-align:left">Market</p></td> 
       <td class="aleft" width="14.52%"><p style="text-align:left">19</p></td> 
       <td class="aleft" width="11.33%"><p style="text-align:left">3˚</p></td> 
       <td class="aleft" width="29.04%"><p style="text-align:left">Market</p></td> 
       <td class="aleft" width="15.19%"><p style="text-align:left">19</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="29.92%"><p style="text-align:left">Entrepreneurial culture</p></td> 
       <td class="aleft" width="14.52%"><p style="text-align:left">16</p></td> 
       <td class="aleft" width="11.33%"><p style="text-align:left">4˚</p></td> 
       <td class="aleft" width="29.04%"><p style="text-align:left">Financial support</p></td> 
       <td class="aleft" width="15.19%"><p style="text-align:left">14</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="29.92%"><p style="text-align:left">Mother university</p></td> 
       <td class="aleft" width="14.52%"><p style="text-align:left">14</p></td> 
       <td class="aleft" width="11.33%"><p style="text-align:left">5˚</p></td> 
       <td class="aleft" width="29.04%"><p style="text-align:left">Entrepreneurial profile</p></td> 
       <td class="aleft" width="15.19%"><p style="text-align:left">11</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="29.92%"><p style="text-align:left">Institutional policy</p></td> 
       <td class="aleft" width="14.52%"><p style="text-align:left">9</p></td> 
       <td class="aleft" width="11.33%"><p style="text-align:left">6˚</p></td> 
       <td class="aleft" width="29.04%"><p style="text-align:left">Partnerships</p></td> 
       <td class="aleft" width="15.19%"><p style="text-align:left">10</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="29.92%"><p style="text-align:left">Team</p></td> 
       <td class="aleft" width="14.52%"><p style="text-align:left">8</p></td> 
       <td class="aleft" width="11.33%"><p style="text-align:left">7˚</p></td> 
       <td class="aleft" width="29.04%"><p style="text-align:left">Institutional policy</p></td> 
       <td class="aleft" width="15.19%"><p style="text-align:left">10</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="29.92%"><p style="text-align:left">Scope -Innovation Ecosystem</p></td> 
       <td class="aleft" width="14.52%"><p style="text-align:left">6</p></td> 
       <td class="aleft" width="11.33%"><p style="text-align:left">8˚</p></td> 
       <td class="aleft" width="29.04%"><p style="text-align:left">Environmental factors</p></td> 
       <td class="aleft" width="15.19%"><p style="text-align:left">9</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="29.92%"><p style="text-align:left">Government</p></td> 
       <td class="aleft" width="14.52%"><p style="text-align:left">5</p></td> 
       <td class="aleft" width="11.33%"><p style="text-align:left">9˚</p></td> 
       <td class="aleft" width="29.04%"><p style="text-align:left">Team</p></td> 
       <td class="aleft" width="15.19%"><p style="text-align:left">8</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="29.92%"><p style="text-align:left">Portfolio</p></td> 
       <td class="aleft" width="14.52%"><p style="text-align:left">3</p></td> 
       <td class="aleft" width="11.33%"><p style="text-align:left">10˚</p></td> 
       <td class="aleft" width="29.04%"><p style="text-align:left">Organizational culture</p></td> 
       <td class="aleft" width="15.19%"><p style="text-align:left">4</p></td> 
      </tr> 
     </table>
    </table-wrap>
    <p>Source: authors.</p>
    <p>The analysis of the categories associated with failure factors and those linked to success factors revealed similarities between the two sets of categories. <xref ref-type="table" rid="table7">
      Table 7
     </xref> identifies categories with identical names and others with different names but equivalent meanings. Despite these similarities, the perspectives described by the authors differ. When referring to failure, the focus is on negative aspects of the process of creating and maintaining university spin-offs. Conversely, success is viewed from a positive perspective, emphasizing factors associated with each category that contribute to the creation and sustainability of university spin-offs.</p>
    <p>Categories with identical names across both failure and success factors include Management, Market, Mother University, Institutional Policy, and Team. Other categories, while differing in name, are equivalent due to shared characteristics among the factors they encompass.</p>
    <p>
     <xref ref-type="table" rid="table7">
      Table 7
     </xref> indicates that when addressing failure in the creation and maintenance of university spin-offs, articles highlight resource availability as the primary issue. For success, management-related aspects are identified as essential for the creation and sustainability of university spin-offs.</p>
    <p>Failure factors grouped under the Resources category are primarily related to the lack of infrastructure and financial resources. A comparison of the identified categories shows that Resources (failure factors) and Financial Support (success factors) are equivalent, as both highlight inadequate financial resources as a critical factor influencing the creation and maintenance of university spin-offs.</p>
    <p>
     <xref ref-type="table" rid="table7">
      Table 7
     </xref> also reveals that success factors categorized under “Financial Support” rank fourth in terms of citations regarding the creation and maintenance of university spin-offs. This indicates that the relevance of financial support for spin-off success is less significant compared to its equivalent failure category, “Resources,” which ranks at the top as the primary challenge in the creation and maintenance of university spin-offs. While lack of funding and infrastructure is a critical challenge for universities, they can overcome these barriers by adopting a strategic approach focused on internal innovation, local partnerships, efficient utilization of existing resources, and human capital development. These approaches can create an environment conducive to innovation and collaboration even without significant external support, helping universities address financial constraints and poor infrastructure.</p>
    <p>However, there are some strategic and practical approaches that can be adopted to effectively address these barriers, even in limited contexts. These include: maximizing the use of existing resources, optimizing existing infrastructure, using digital platforms, fostering innovation within the university, encouraging collaborative research and development projects within the institution itself, leveraging local and regional partnerships, collaborations with other universities, supporting smaller public and private funds, leveraging internal human capital, fostering a culture of sustainability and efficiency, fostering an entrepreneurial culture by encouraging the creation of spin-offs.</p>
    <p>These data also show that aspects related to “Management” were among the most cited failure factors in the context of creating and maintaining university spin-offs. The consolidation presented in <xref ref-type="table" rid="table7">
      Table 7
     </xref> highlights that, in both perspectives analyzed in this study, management plays a critical role in the creation and sustainability of university spin-offs.</p>
    <p>Regarding the “Market” category, which has the same name in both failure and success factors, it ranks third with an equal number of citations (19) in the literature. This suggests that market demand can either negatively or positively affect spin-offs, depending on the level of investment and attention given by the spin-off to market engagement.</p>
    <p>“Market demand” is an ambivalent factor, that is, it can be both a factor of success and a factor of failure, depending on how the business responds to this demand, whether there is a good understanding of the market, and whether management is able to adapt to its changes. The key to the transition between these two scenarios lies in the ability to adapt, strategic planning and differentiation in the market. The ability to anticipate market trends and adapt supply to changing customer needs can make demand a success factor; A lack of adequate market research or an inability to understand market nuances can turn market demand into a failure factor. Businesses that have flexible, agile management and a team capable of reacting to changes in demand (such as new technologies or regulations) can turn favorable demand into success; If management is slow or unable to change the direction of the business in response to changing market conditions, demand can quickly become a failure factor. Companies that can create strong market differentiation, through innovation or a unique business model, can better take advantage of demand and stand out, ensuring success. If the business fails to distinguish itself from competitors or loses its competitive advantage, demand may be insufficient to ensure success.</p>
    <p>The relationship and support from the “Mother University” stood out as a significant factor for the success of university spin-offs but had a more modest role among failure factors. Support from the originating university can have a considerable impact when the institution proactively provides resources, such as infrastructure and training in areas where the spin-off lacks expertise.</p>
    <p>For the category “Institutional Policy” of the mother university, it was cited as both a failure and success factor for the creation and maintenance of university spin-offs, with similar citation frequencies. The absence of institutional policy was linked to failure factors, while its existence was associated with success.</p>
    <p>In terms of the mother university’s culture, failure factors highlighted a lack of entrepreneurial focus, such as insufficient training in entrepreneurship and the absence of qualified professionals within the university to provide guidance. Conversely, the “Organizational Culture” category in success factors emphasized entrepreneurial culture alongside other organizational aspects contributing to the success of university spin-offs.</p>
    <p>Regarding the culture of the mother university, failure factors highlight the lack of entrepreneurial orientation, including insufficient entrepreneurship training and a shortage of qualified professionals within the university to provide guidance. In contrast, success factors within the “Organizational Culture” category emphasize the presence of an entrepreneurial culture alongside other organizational aspects.</p>
    <p>It is worth noting that the “Entrepreneurial Culture” category ranks fourth among failure factors in terms of frequency of citation in the articles. Conversely, the equivalent “Organizational Culture” category, when considering success factors, is ranked as having the least influence on the creation and maintenance of university spin-offs. Different cultural contexts play an essential role in the creation and development of university spin-offs, especially in regions with less developed entrepreneurial ecosystems. The impact of local culture can be observed in both the success and failure factors indicated in the tables above.</p>
    <p>The equivalence between the “Portfolio” and “Entrepreneurial Profile” categories lies in their shared focus on intellectual property protection and the development of new products by spin-offs. Among the failure factors, the “Portfolio” category was cited the least, occupying the last position in the defined categories. This indicates a lower influence of the failure factors in this category on the creation and maintenance of university spin-offs. On the success factors list, the “Entrepreneurial Profile” of the university spin-off is considered to have a moderate impact on achieving business objectives.</p>
    <p>In regions where entrepreneurship is not yet consolidated, there are structural and cultural challenges that affect the viability of spin-offs, such as: Low culture of innovation, lack of infrastructure which are essential for the development of spin-offs and resistance to innovative business models, as traditional companies may not recognize the value of new technologies developed at universities.</p>
    <p>The categories “Scope-Innovation Ecosystem” (failure factors) and “Environmental Factors” (success factors) are equivalent in terms of factors related to the innovation ecosystem. While failure factors highlight the lack of external support from the environment where spin-offs operate, success factors extend beyond the innovation ecosystem (which accounts for most of the factors cited) to include aspects of the regional economy.</p>
    <p>Furthermore, the category “Scope – Innovation Ecosystem” (failure factors) aligns with the position of the related category “Environmental Factors” (success factors), differing only in the number of citations. Compared to the other categories, both present a relatively small number of factors, suggesting a smaller impact on the creation and maintenance of academic or university spin-offs. For spin-offs to be successful in challenging cultural contexts, especially in regions with less developed ecosystems, some strategies can be adopted: creation of collaborative networks to establish connections between universities, the private sector and the government to strengthen support for entrepreneurship; change in academic culture to encourage entrepreneurial training programs and bring researchers closer to the market; and public policies to encourage the creation of financing mechanisms and legal support for spin-offs; and internationalization to explore partnerships with more developed ecosystems to overcome local barriers.</p>
    <p>The “Partnership” category, related to success factors, emphasizes collaboration among actors within the spin-off’s ecosystem. Key success factors include establishing external connections beyond the university and building collaborative relationships with other partners.</p>
    <p>The “Government” category listed among failure factors did not have a corresponding category for success factors in the creation and maintenance of academic or university spin-offs. The cited failure factors highlight the lack of governmental support.</p>
    <p>The analysis and comparison of the categories encompassing failure and success factors demonstrate similarities between them. However, the influence of these categories, whether as drivers of success or failure, directly impacts the development of university spin-offs—companies derived from technologies created within universities.</p>
    <p>In this context, the data from this research were compared with the four stages of university spin-off creation proposed by <xref ref-type="bibr" rid="scirp.141880-40">
      Ndonzuau, Pirnay, and Surlemont (2002)
     </xref>, as illustrated in <xref ref-type="fig" rid="fig1">
      Figure 1
     </xref>. The comparison revealed that some factors identified in this study align with those emphasized in the authors’ model, impacting the creation and maintenance of university spin-offs.</p>
    <p>In Stage 1 of the model, the authors highlight the importance of university culture, noting that the existence of an entrepreneurial culture and university policies focused on entrepreneurship are essential for the success of spin-offs. This study corroborates these findings, identifying the absence or deficiency of an entrepreneurial culture and university policies as key failure factors. Conversely, the presence of these elements, especially when accompanied by institutional support for spin-offs, is highlighted as a success factor in their creation and maintenance.</p>
    <p>Stage 1 also emphasizes the need for support from the mother university, such as providing advisory services to entrepreneurs, a factor also reflected in this study under the “Mother University” category. Additionally, the model underscores the role of the mother institution in identifying commercially viable innovations. This study aligns with these findings, identifying failure factors related to this issue under the “Portfolio” category, while success factors are grouped under the “Entrepreneurial Profile” category.</p>
    <p>The “Portfolio” (failure factors) and “Entrepreneurial Profile” (success factors) categories identified in this study also correspond to Stage 2 of the model, which stresses the need for intellectual property protection to enable commercial exploitation.</p>
    <p>Stage 2 further highlights barriers such as inadequate spin-off management and insufficient funding, which align with the findings of this study. According to <xref ref-type="table" rid="table7">
      Table 7
     </xref>, “Resources,” the most cited failure factor, and “Management,” the second most cited, reflect these challenges. Supporting this, the “Management” and “Financial Support” categories in this study encompass success factors critical to the creation and maintenance of university spin-offs.</p>
    <p>Stage 3 addresses market integration, relationships with the mother university, and access to financial, material, and human resources. These aspects are mirrored in this study (see <xref ref-type="table" rid="table7">
      Table 7
     </xref>), where corresponding categories are cited as both failure factors (Market, Mother University, Resources, and Team) and success factors (Market, Mother University, Financial Support, and Team). However, their impacts differ, as reflected in the rankings of these categories in <xref ref-type="table" rid="table7">
      Table 7
     </xref>.</p>
    <p>Entrepreneurial competence is a dynamic factor that can be a factor of success or failure depending on how the entrepreneur applies it. It is directly related to management skills, strategic vision, adaptation to market changes and leadership capacity. Success occurs when these competencies are well developed, while failure occurs when there are gaps in these areas, such as lack of vision, resistance to change or failures in strategic execution. Thus, entrepreneurial competence can transition between these two states depending on the situation, context and actions taken by the entrepreneur.</p>
    <p>Finally, Stage 4 of the model points to concerns such as insufficient personnel and infrastructure, financial issues, inefficient management, and relocation of the spin-off. These challenges are consistent with the failure factors identified in this study, specifically the categories “Team,” “Mother University,” “Resources,” “Management,” and “Scope.”</p>
    <p>The authors of the model (<xref ref-type="bibr" rid="scirp.141880-40">
      Ndonzuau, Pirnay, &amp; Surlemont, 2002
     </xref>) primarily highlight barriers to the creation of university spin-offs while also proposing strategies to mitigate these challenges. All the aspects identified by the authors align with the categories found in this study. However, the model presents fewer specific success or failure factors compared to this research, which identifies multiple factors—both positive and negative—within each category that influence the creation and maintenance of university spin-offs.</p>
    <p>The role of the mother university is particularly significant in this context. As the institution from which the spin-off originates, numerous success and failure factors are linked to it. These include institutional policies that encourage and support the creation of spin-offs through investments, infrastructure, and career incentives for researchers. Additionally, the university’s role extends to providing training for spin-off managers, particularly through specialized technology transfer departments; offering networks and connections to newly established spin-offs; supplying new technologies to spin-offs; fostering an entrepreneurial environment, including supporting and maintaining innovation habitats like incubators; and recognizing its mission to deliver research outcomes to society.</p>
    <p>In this context, addressing the factors of failure and success outlined in this study, and categorized systematically, is essential for the effective creation and maintenance of university spin-offs. These factors provide valuable insights for developing structures and strategies that enable more targeted and successful spin-off initiatives.</p>
   </sec>
  </sec><sec id="s5">
   <title>5. Conclusion</title>
   <p>The defined categories, to varying degrees, significantly influence the creation and maintenance of academic or university spin-offs. These categories, along with their associated success and failure factors, must be carefully considered when developing this type of enterprise.</p>
   <p>The most influential failure factors are linked to the following categories: Resources, which involve financial, infrastructure, and personnel challenges; Management, which includes inadequate administration, conflicts of interest, lack of business guidance, and strained relationships with the parent university; and Market, which refers to limited knowledge and difficulties in market insertion for the spin-off. Additionally, the study highlights failure factors related to the parent university’s entrepreneurial culture, its relationship with the spin-off, institutional policies, the spin-off team, the innovation ecosystem where the spin-off is located, government support for innovation, and the spin-off’s portfolio.</p>
   <p>Regarding success factors critical to the creation and maintenance of spin-offs, the following categories stand out: Management, which emphasizes effective leadership, entrepreneurial skills, and the adopted business model; Parent University, focusing on its supportive relationship with the spin-off; and Market, identifying its characteristics to facilitate the spin-off’s integration.</p>
   <p>The research also identified other positive aspects that contribute to the success of spin-offs, including adequate financial support, an entrepreneurial profile, partnerships, suitable institutional policies from the parent university, favorable environmental factors in both the market and the innovation ecosystem, an adequate spin-off team with the right size, experience, and diversity, and an entrepreneurial organizational culture within the parent university.</p>
   <p>Based on the conclusions about the success and failure factors in the creation and maintenance of academic spin-offs, some suggestions for future studies can be made, with the aim of deepening the understanding of this topic and contributing to the improvement of practices and policies in this field. Here are some suggestions: study of the impact of institutional policies on the success of spin-offs; analysis of the entrepreneurial culture in universities and its influence on spin-offs; assessment of the university-spin-off relationship and its effects on success; the influence of the local innovation ecosystem on the performance of spin-offs; the relationship between public and private funding and the growth of spin-offs; analysis of market barriers to academic spin-offs; comparison between spin-offs from different areas of knowledge; longitudinal study on the evolution of spin-offs.</p>
   <p>These suggestions for future studies can not only deepen the knowledge about the process of creating and maintaining academic spin-offs, but also provide valuable insights for universities, policymakers, entrepreneurs and investors interested in supporting and maximizing the success of these companies.</p>
  </sec>
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