The management of the CUKIS gave administrative approval for the study, and the Department of Surgery approved the protocol and the conduct of the study. All information obtained from patient files was kept completely anonymous.

Of the 1476 patients operated on during our study period, 486 were followed up postoperatively. We identified 170 patients with early postoperative complications, a prevalence of 35.0%. Of the 170 patients with postoperative complications, 35 died, giving a mortality rate of 20.6%. The mean age was 41.5 years, with a standard deviation of 24.2 years; the age group 60 - 79 was most affected by CPO, with 28.2%. Many patients were male (74.1%).

The majority of POC cases were admitted via the emergency department 52.9%. The most common medical histories were arterial hypertension, gastritis and diabetes (respectively)12.9%, 10.0% and 7.1%, while surgical histories such as hernia repair and appendectomy were more prevalent (respectively) 6.5% and 5.9%. Acute generalised peritonitis and benign prostatic hypertrophy were the most frequent preoperative diagnoses in general and visceral surgery, with respectively 14.1% and 12.9%. Fractures were more frequent in orthopaedic trauma, at 17.6%. The preoperative period was less than 10 days in most cases (66.5%). Most patients operated on were classified as ASA 1 (66.5%). Benign prostatic hypertrophy and ileal perforation were intraoperative diagnoses the most frequent in general and visceral surgery, with respectively 12.4% and 4.1%. Fractures of two leg bones were more frequent in orthopaedic trauma, at 5.9%. Exploratory laparotomy was the most common surgical procedure in general and visceral surgery (30.0%), followed by adenomectomy (11.8%), and osteosynthesis was more common in orthopaedic trauma (12.4%), followed by amputation (5.9%). General anaesthesia was used most often (92.4%). The types of surgery according to Altemeier 4 were the most frequently performed. 72.9% of patients had received drug treatment without resuscitation, and surgical site infection was the most frequent CPO in 45.3% of cases.

3.3.1. Preoperative Predictive Factors

Transfer as a mode of admission, previous laparotomy, preoperative diagnoses such as acute generalised peritonitis, intestinal obstruction, traumatic wound, diabetic foot and tumours were predictive factors associated with postoperative mortality (Tables 1-3).

Table 1. Distribution of cases according to analysis of predictive factors linked to mode of admission

¹% (n/N); ²cOR = crudde odds ratio; aOR = adjusted odds ratio; CI = confidence interval.

Table 2. Distribution of cases according to analysis of predictive factors linked to patient history.

¹% (n/N); ²cOR = crudde odds ratio; aOR = adjusted odds ratio; CI = confidence interval.

Table 3. Distribution of cases according to analysis of predictive factors linked to preoperative diagnoses.

¹% (n/N); ²cOR = crudde odds ratio; aOR = adjusted odds ratio, CI = confidence interval.

3.3.2. Per- and Postoperative Predictive Factors

Surgical intervention such as exploratory laparotomy and drug treatment with postoperative resuscitation were predictive factors during and after the operation (Table 4 and Table 5).

Table 4. Distribution of cases according to analysis of prognostic factors linked to the nature of the surgical procedure.

¹% (n/N); ²cOR = crudde odds ratio; aOR = adjusted odds ratio, CI = confidence interval.

Table 5. Distribution of cases according to analysis of predictive factors linked to postoperative treatment.

¹% (n/N); ²cOR = crudde odds ratios; aOR = adjusted odds ratio; CI = confidence interval; ³TM = Medicinal treatment; ⁴TM + R = Medicinal treatment+ resuscitation.

The prevalence of postoperative complications in our study was 35.0%. Our prevalence is close to that found by Mukakala et al. [8] in Lubumbashi, which was 32.2%. It is higher than those of Tonye et al. [2] and Azabaliet al. [14] who found a prevalence of 14.3% and 12.8% respectively. Our high prevalence of postoperative complications could be explained, on the one hand, by the difficult socio-economic conditions of our population, which are unable to take good care of itself in the event of illness and, on the other hand, by the precarious working conditions at CUKIS, which do not favour good patient care.

Of the 170 patients who had postoperative complications, 35 died, giving a mortality rate of 20.6%. These results are lower than those of Mukakala et al. [8], whose study found a mortality of rate 30.4%. This can be explained by the fact that the CUKIS surgery department where we carried out our study is staffed by specialists, doctors on specialisation and trainee doctors who are responsible for the daily follow-up of patients undergoing surgery, which means that POCs are detected early and managed. However, several authors have found mortality rates lower than ours in their series, including Assouto et al. [13], Coulibaly et al. [1], Gaudeuille et al. [15] and Wasukama et al. [12], who found mortality rates of 13%, 1.9%, 1.3% and 13% respectively. Our high mortality rate could be explained by the same reason; on the one hand, by the difficult socio-economic conditions of our population, which do not manage to well cope with care in the event of POC, and on the other hand, by the working conditions precarious at CUKIS, which do not favour good management of POC.

The mean age was 41.5 years, with a standard deviation of 24.2 years, and the majority were male (74.1%) or married (56.5%). Our results are like those of Bang et al. [11], who found that the mean age of patients was 37.6 ± 13 years and 66.7% were male. This age corresponds to that of a young adult during physical and social activity, who is likely to be exposed to many of life’s hazards, particularly illness.

The majority of POC cases were admitted by emergency departments, i.e. 52.9%. These results are like those of Assouto et al. [13], Mukakalaet al. [8], Tonye et al. [2], Coulibaly et al. [1] and Ahmedou et al. [16], who found that respectively 83.2%, 80%, 71%, 65% and 51.2% of patients admitted by emergency departments. Our results can be explained by the fact that in our study, most of the pathologies found were surgical emergencies, which could explain most emergency admissions. In addition, patients admitted as emergencies are often those with serious conditions requiring urgent care or transfer to a specialist medical facility with qualified staff and appropriate technical facilities.

The most prevalent medical histories were arterial hypertension, gastritis and diabetes with 12.9%, respectively10.0% and 7.1% of cases, and surgical histories such as hernia repair and appendectomy were more prevalent with 6.5% and 5.9% respectively. Ndayisabaet al. [17] in their study, found undernutrition, HIV, diabetes and obesity. Ugumbaet al. [7] found arterial, hypertension, diabetes, haemorrhagic diathesis, HIV/AIDS and cancer in 46.43% of cases. The above-mentioned authors were not interested in surgical history. Our results can be explained by the fact that hypertension, gastritis and diabetes are three pathologies in our environment, linked to a lifestyle dominated by stress and an inappropriate diet due to poverty. Acute generalised peritonitis and benign prostatic hypertrophy were the most frequent preoperative diagnoses in general and visceral surgery, while fractures were more frequent in orthopaedic trauma. Mukakala et al. [8] found acute generalised peritonitis followed by acute intestinal obstruction to be the most frequent operative indications, which could be explained by the fact that this author’s work concerned acute abdominal surgery whereas our data concerned all surgical pathologies whatever their severity. Regarding trauma and orthopaedic surgery, our results corroborate those of Gogouaet al. [19] in their study of early orthopaedic trauma revision at the University Hospital Treichville-Abidjan, found that the initial lesions were varied and dominated by open fractures. The high frequency of fractures observed in our series can be explained by the high rate of road traffic accidents in our environment, which constitute the main aetiology.

The time between hospitalisation and surgery was less than 10 days in most of our cases (66.5%). Our results are in line with those of Ndayisabaet al. [17], Bangetal. [11] and Soumahet al. [20] who found preoperative delays of 5 days, 4 days and 3 days respectively on average. Magagi et al. [21] found a very short preoperative delay of 9 hours with extremes of 1 - 48 hours. The short delay observed by the others can simply be explained by the fact that their work concerned surgical emergencies, which is not the case for our series.

ASA class 1 was more dominant in our study. Our result differs from that found by Gaudeuilleet al. [15], in his study of postoperative complications in the paediatric surgery department in Bangui, who found a predominance of ASA class 2. Our result also differs from that of Mukakala et al. [8] who found that many patients were in ASA3 class. It agrees with Ndouret al. [22] who found that most patients were classified ASA1. The predominance of ASA1 patients observed in our series can be largely explained by the fact that many of our patients consulted for less serious pathologies of severity moderate such as hernias and appendicitis, pathologies which have less impact on the general condition of patients.

Most surgical procedures were performed by specialists. Our results are like those of Mukakala et al. [8] who also found that most surgical interventions were performed by specialists. This result can be explained by the fact that the CUKIS surgery department has several specialists with skills in several areas of surgery.

Benign prostatic hypertrophy and ileal perforation were the most frequent intraoperative diagnoses in general and visceral surgery, while fracture of two leg bones was more frequent in orthopaedic trauma. Our results differ from those of Bang et al. [11] who found respectively gastric perforation, simple acute catarrhal appendicitis, intestinal occlusion due to tumour and ileal perforation, the latter not having worked simultaneously in orthopaedic trauma surgery. Adamou etal. [23] in their study on diagnostic delay and prognostic implications in an African setting; Case of digestive surgery emergencies at Zinder national hospital in Niger, found ileal perforation, appendicular perforation and strangulated hernias. Our results can be explained by the fact that acute generalised peritonitis and benign prostatic hypertrophy were the pathologies most frequently encountered preoperatively. Concerning trauma and orthopaedic surgery, our results concur with those of Gogoua et al. [19] in his study of early revision orthopaedic trauma at the Treichville-Abidjan University Hospital, who found that the initial lesions were varied and dominated by open fractures. The predominance of open fractures of 2 leg bones in our series can be explained by the poor muscular coverage of the leg bones, at least on their anteromedial aspect, which makes them vulnerable. Exploratory laparotomy was the most common surgical procedure in general and surgery visceral, followed by adenomectomy, and osteosynthesis was more common in orthopaedic trauma, followed amputation. Banget al. [11] in his study, found laparotomy for resection/anastomosis, perforation suture, adhesiolysis, etc. followed by appendectomy. Tonyeet al. [2] found caesarean sections: 159 cases (60%); salpingectomies, hernia repairs and appendectomies. This could be explained by the fact that Tonye had also worked in gynaecology obstetrics. Our results can be explained by the fact that the diagnoses most frequently found in our series were benign prostatic hypertrophy, ileal perforation and fracture of two legs, which are the indications for the above-mentioned operations. General anaesthesia was used in many cases. Our results corroborate those of Matsanga et al. and Gayeet al. [24][25] who found that general anaesthesia was predominant in 100% and 95.6% of cases respectively. The fact that general anaesthesia was used in most surgical cases in the Department of Surgery at the CUKIS can be explained by the fact that these clinics have neither an organised anaesthesia and intensive care service, nor qualified staff in this field. In addition, material unavailability may also explain the predominance of general anaesthesia, but also, most surgical operations in our series require general anaesthesia.

The types of surgery according to Altemeier 4 were more frequent in patients with CPO. Our results differ from those of Gaudeuilleet al. [15] who found that majority of surgical procedures (36.43%) were classified as Altemeier 1. Our results can be explained by the fact that in our series, most intraoperative diagnoses are indications for contaminated or dirty surgical procedures, such as ileal perforation. Surgical site infection was the most frequent CPO in 45.3% of cases. Our results agree with those of Ndouret al. [22] who found that surgical site infection was the CPO most frequent with 64.1%.

This result can be explained by the fact that in countries with limited resources such as ours, the poor state of hospital infrastructures and equipment, the insufficient supply and unreliable quality of medicines, shortcomings in administrative management and infection control efforts, and chronic under-funding are all factors that explain the high frequency of surgical site infections.

4.3.1. Preoperative Predictive Factors

Transfer as the mode of admission, previous laparotomy, diagnoses preoperative such as acute generalised peritonitis, intestinal obstruction, wound traumatic, diabetic foot and tumours were predictive factors preoperative associated with postoperative mortality. Regarding the mode of admission, our results differ from those of Assoutoet al. [13]. In his study, he pointed out that most deaths were reported in patients undergoing emergency surgery, and the risk of death was multiplied by 5.7 in the case of emergency surgery. Our results can be explained by the fact that most patients are transferred to the CUKIS in a very precarious clinical state, which means that their postoperative prognosis is very poor. In relation to surgical indications, Coulibalyet al. [1] found that the causes of death were acute generalised peritonitis, intestinal intussusception, hydrocephalus, meningocele, Hirschsprung and laparoschisis’s disease. This can be explained by the fact that this author worked in paediatric surgery. Our results can be explained by the fact that the above pathologies are in the majority in our series.

4.3.2. Per- and Postoperative Predictive Factors

Surgical intervention such as exploratory laparotomy and treatment drug with postoperative resuscitation were predictive factors both intraoperatively and postoperatively. Our results are like those of Razafindraibe et al. [26] who found in their study that exploratory laparotomy was significantly associated with the occurrence of intraoperative death. These authors made no mention of postoperative treatment. Our results are in line with those of Gaudeuilleet al. [15] found that postoperative may be influenced by the age mortality patient’s, pathologies, type of POC and surgical procedures. Our results can be explained by the fact that preoperative such as acute generalised peritonitis and intestinal obstruction diagnoses are predictive factors of preoperative mortality and are managed by exploratory laparotomy. In addition, patients who have undergone exploratory laparotomy are normally treated with drugs and resuscitated postoperatively.