<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v3.0 20080202//EN" "http://dtd.nlm.nih.gov/publishing/3.0/journalpublishing3.dtd">
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="3.0" xml:lang="en" article-type="research article">
 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">
    wjcd
   </journal-id>
   <journal-title-group>
    <journal-title>
     World Journal of Cardiovascular Diseases
    </journal-title>
   </journal-title-group>
   <issn pub-type="epub">
    2164-5329
   </issn>
   <issn publication-format="print">
    2164-5337
   </issn>
   <publisher>
    <publisher-name>
     Scientific Research Publishing
    </publisher-name>
   </publisher>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="doi">
    10.4236/wjcd.2025.153012
   </article-id>
   <article-id pub-id-type="publisher-id">
    wjcd-141472
   </article-id>
   <article-categories>
    <subj-group subj-group-type="heading">
     <subject>
      Articles
     </subject>
    </subj-group>
    <subj-group subj-group-type="Discipline-v2">
     <subject>
      Medicine 
     </subject>
     <subject>
       Healthcare
     </subject>
    </subj-group>
   </article-categories>
   <title-group>
    Complexity of Serpiginous Right Atrium Thrombus Management in Acute Pulmonary Embolism Patient: A Clinical Case Report
   </title-group>
   <contrib-group>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Jean Bertrand
      </surname>
      <given-names>
       Irakoze
      </given-names>
     </name>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Sana
      </surname>
      <given-names>
       Samoura
      </given-names>
     </name>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Dieu-Donnée Kaziga
      </surname>
      <given-names>
       Wiyaou
      </given-names>
     </name>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Mehounou Sémessa Yévédo Romuald Narcisse
      </surname>
      <given-names>
       Hounsou
      </given-names>
     </name>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Sami
      </surname>
      <given-names>
       Assi
      </given-names>
     </name>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Sylvain
      </surname>
      <given-names>
       Chanseaume
      </given-names>
     </name>
    </contrib>
   </contrib-group> 
   <aff id="affnull">
    <addr-line>
     aCardiology Department, Montluçon Hospital Center, Montluçon, France
    </addr-line> 
   </aff> 
   <pub-date pub-type="epub">
    <day>
     24
    </day> 
    <month>
     03
    </month>
    <year>
     2025
    </year>
   </pub-date> 
   <volume>
    15
   </volume> 
   <issue>
    03
   </issue>
   <fpage>
    135
   </fpage>
   <lpage>
    141
   </lpage>
   <history>
    <date date-type="received">
     <day>
      22,
     </day>
     <month>
      December
     </month>
     <year>
      2024
     </year>
    </date>
    <date date-type="published">
     <day>
      21,
     </day>
     <month>
      December
     </month>
     <year>
      2024
     </year> 
    </date> 
    <date date-type="accepted">
     <day>
      21,
     </day>
     <month>
      March
     </month>
     <year>
      2025
     </year> 
    </date>
   </history>
   <permissions>
    <copyright-statement>
     © Copyright 2014 by authors and Scientific Research Publishing Inc. 
    </copyright-statement>
    <copyright-year>
     2014
    </copyright-year>
    <license>
     <license-p>
      This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/
     </license-p>
    </license>
   </permissions>
   <abstract>
    The presence of the right atrial thrombus (RAT) is a life-threatening condition often associated with acute pulmonary embolism (PE). This case report details a 63-year-old male patient who presented with a serpiginous RAT and a massive PE. Despite the administration of both anticoagulation and fibrinolytic therapies, the patient unfortunately experienced sudden cardiac arrest and succumbed to the condition.
   </abstract>
   <kwd-group> 
    <kwd>
     Thrombus
    </kwd> 
    <kwd>
      Echocardiography
    </kwd> 
    <kwd>
      Anticoagulation
    </kwd>
   </kwd-group>
  </article-meta>
 </front>
 <body>
  <sec id="s1">
   <title>1. Background</title>
   <p>A floating right atrial thrombus (RAT) is often associated with cases of massive pulmonary embolism. The etiology of RAT is diverse and includes deep vein thrombosis. The clinical implications of RAT are significant, with potential outcomes including severe complications or mortality. The management of RAT remains contentious due to the absence of standardized international guidelines. Although treatments such as anticoagulation therapy and surgical embolectomy have demonstrated efficacy, the mortality rate remains notably high, with nearly 25% of patients not surviving the condition. On the other hand, neglecting to treat RAT almost invariably leads to fatal outcomes <xref ref-type="bibr" rid="scirp.141472-1">
     [1]
    </xref> <xref ref-type="bibr" rid="scirp.141472-2">
     [2]
    </xref>.</p>
  </sec><sec id="s2">
   <title>2. Case Presentation</title>
   <p>A 63-year-old male presented to the emergency department with complaints of feeling unwell since getting out of bed. He was discharged from another hospital three days prior, having undergone a total prostatectomy for prostate cancer two weeks earlier. Postoperatively, he had been on a regimen of 4000 IU per day of prophylactic low molecular weight heparin. Since his discharge, he reported experiencing dyspnea with minimal exertion. On the morning of presentation, he experienced a presyncope upon rising from bed. A friend, who is a firefighter, advised him to seek medical attention. Upon arrival at the emergency department, the patient was conscious and appeared in relatively good general condition. History noted no cardiovascular diseases.</p>
   <sec id="s2_1">
    <title>2.1. Physical Examination and Exploration Results</title>
    <p>The physical examination revealed a blood pressure of 112/87 mm Hg, a heart rate of 101 beats per minute, a temperature of 36.8 degrees Celsius, a peripheral oxygen saturation of 90% on room air, and a respiratory rate of 46 breaths per minute. The cardiovascular examination was unremarkable except for regular tachycardia, and pulmonary auscultation was also normal. An electrocardiogram (ECG) performed immediately showed an incomplete right bundle branch block, sinus tachycardia at 104 beats per minute, and an S1Q3T3 pattern. Laboratory results indicated hemoglobin at 13.5 g/dL, white blood cell count at 11.4 × 10<sup>9</sup>/L, markedly elevated D-dimer levels over 10,000 ng/mL, and arterial blood gas analysis revealed a shunt effect with PCO<sub>2</sub> at 23 mm Hg and PO<sub>2</sub> at 55 mm Hg. All other laboratory findings are summarized in <xref ref-type="table" rid="table1">
      Table 1
     </xref>. An emergent computed tomography pulmonary angiogram (CTPA) confirmed extensive proximal and distal pulmonary embolism (PE) in both lung fields, with thrombus at the bifurcation of the pulmonary artery trunk and in both pulmonary artery branches, without evidence of pulmonary infarction (<xref ref-type="fig" rid="fig1">
      Figure 1
     </xref>).</p>
    <p>Transthoracic echocardiography (TTE) revealed the right ventricular dilation with systolic dysfunction and the presence of a large serpiginous thrombus in the right atrium measuring approximately 5 cm in diameter, oscillating between the atrium and the right ventricle through the tricuspid valve (<xref ref-type="fig" rid="fig2">
      Figure 2
     </xref>).</p>
   </sec>
   <sec id="s2_2">
    <title>2.2. Management</title>
    <p>After receiving a 5000 UI loading dose bolus of unfractionated heparin, the patient was immediately admitted to the cardiac intensive care unit, where his hemodynamic state remained relatively stable under continuous heparin infusion. The family was informed of the possibility of fibrinolysis despite the high hemorrhagic risk, as the patient had recently undergone surgery. A few hours later, the patient began to vomit, became desaturated, and was put on oxygen at a rate of 15 liters per minute via mask. Alteplase was administered with an initial bolus of 10 mg, followed by 90 mg over 2 hours. The intensive care unit agreed to the transfer; however, as the patient was leaving the room, he went into cardiac arrest. We performed cardiac resuscitation and administered a 1 mg bolus of adrenaline, followed by 1 mg every 3 minutes. The patient was intubated, and we continued cardiopulmonary resuscitation. After a few minutes, he regained a heart rhythm briefly but then unfortunately fell into asystole again. After an hour of resuscitation efforts, we decided to cease resuscitation, and the death was communicated to the family, whose members were still on site.</p>
    <fig id="fig1" position="float">
     <label>Figure 1</label>
     <caption>
      <title>Figure 1. CTPA: Bilateral massive pulmonary embolism.</title>
     </caption>
     <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/1911617-rId16.jpeg?20250324041706" />
    </fig>
    <fig id="fig2" position="float">
     <label>Figure 2</label>
     <caption>
      <title>Figure 2. Transthoracic echocardiography: Right atrium thrombus.</title>
     </caption>
     <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="" />
    </fig>
    <fig id="fig2" position="float">
     <label>Figure 2</label>
     <caption>
      <title>Figure 2. Transthoracic echocardiography: Right atrium thrombus.</title>
     </caption>
     <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/1911617-rId17.jpeg?20250324041707" />
    </fig>
    <fig id="fig2" position="float">
     <label>Figure 2</label>
     <caption>
      <title>Figure 2. Transthoracic echocardiography: Right atrium thrombus.</title>
     </caption>
     <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/1911617-rId18.jpeg?20250324041707" />
    </fig>
    <table-wrap id="table1">
     <label>
      <xref ref-type="table" rid="table1">
       Table 1
      </xref></label>
     <caption>
      <title>
       <xref ref-type="bibr" rid="scirp.141472-"></xref>Table 1. Results of biological laboratory findings.</title>
     </caption>
     <table class="MsoTableGrid custom-table" border="0" cellspacing="0" cellpadding="0"> 
      <tr> 
       <td class="custom-bottom-td acenter" width="28.61%"><p style="text-align:center">Exam</p></td> 
       <td class="custom-bottom-td acenter" width="32.54%"><p style="text-align:center">Results</p></td> 
       <td class="custom-bottom-td acenter" width="38.85%"><p style="text-align:center">Laboratory referral range</p></td> 
      </tr> 
      <tr> 
       <td rowspan="4" class="custom-top-td acenter" width="28.61%"><p style="text-align:center">Arterial blood gas</p></td> 
       <td class="custom-top-td acenter" width="32.54%"><p style="text-align:center">PH: 7.56 mm Hg</p></td> 
       <td class="custom-top-td acenter" width="38.85%"><p style="text-align:center">7.35 - 7.45</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="32.54%"><p style="text-align:center">PCO<sub>2</sub>: 23 mm Hg</p></td> 
       <td class="acenter" width="38.85%"><p style="text-align:center">35 - 48</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="32.54%"><p style="text-align:center">PO<sub>2</sub>: 55 mm Hg</p></td> 
       <td class="acenter" width="38.85%"><p style="text-align:center">83 - 108</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td acenter" width="32.54%"><p style="text-align:center">HCO<sub>3</sub>: 20.4 mmol/l</p></td> 
       <td class="custom-bottom-td acenter" width="38.85%"><p style="text-align:center">22.2 - 28.3</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td acenter" width="28.61%"><p style="text-align:center">Hb</p></td> 
       <td class="custom-top-td acenter" width="32.54%"><p style="text-align:center">13.5 g/dl</p></td> 
       <td class="custom-top-td acenter" width="38.85%"><p style="text-align:center">13.4 - 16.7</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="28.61%"><p style="text-align:center">PLT</p></td> 
       <td class="acenter" width="32.54%"><p style="text-align:center">250 G/L</p></td> 
       <td class="acenter" width="38.85%"><p style="text-align:center">150 - 400</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="28.61%"><p style="text-align:center">WBC</p></td> 
       <td class="acenter" width="32.54%"><p style="text-align:center">11.03 G/L</p></td> 
       <td class="acenter" width="38.85%"><p style="text-align:center">4 - 11.00</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="28.61%"><p style="text-align:center">PT</p></td> 
       <td class="acenter" width="32.54%"><p style="text-align:center">91%</p></td> 
       <td class="acenter" width="38.85%"><p style="text-align:center">70 - 100</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="28.61%"><p style="text-align:center">ACR</p></td> 
       <td class="acenter" width="32.54%"><p style="text-align:center">0.99</p></td> 
       <td class="acenter" width="38.85%"><p style="text-align:center">0.8 - 1.2</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="28.61%"><p style="text-align:center">Fibrinogen</p></td> 
       <td class="acenter" width="32.54%"><p style="text-align:center">4.14 g/l</p></td> 
       <td class="acenter" width="38.85%"><p style="text-align:center">2.00 - 4.00</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td acenter" width="28.61%"><p style="text-align:center">D-Dimers</p></td> 
       <td class="custom-bottom-td acenter" width="32.54%"><p style="text-align:center">&gt;10000 ng/ml</p></td> 
       <td class="custom-bottom-td acenter" width="38.85%"><p style="text-align:center">&lt;600</p></td> 
      </tr> 
      <tr> 
       <td rowspan="3" class="custom-top-td acenter" width="28.61%"><p style="text-align:center">Blood Ionogram</p></td> 
       <td class="custom-top-td acenter" width="32.54%"><p style="text-align:center">Na<sup>+</sup>: 138 mmol/l</p></td> 
       <td class="custom-top-td acenter" width="38.85%"><p style="text-align:center">136 - 145</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="32.54%"><p style="text-align:center">K<sup>+</sup>: 4 mmol/l</p></td> 
       <td class="acenter" width="38.85%"><p style="text-align:center">3.4 - 4.5</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td acenter" width="32.54%"><p style="text-align:center">Chlore: 102 mmol/l</p></td> 
       <td class="custom-bottom-td acenter" width="38.85%"><p style="text-align:center">98 - 107</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td acenter" width="28.61%"><p style="text-align:center">ASAT</p></td> 
       <td class="custom-top-td acenter" width="32.54%"><p style="text-align:center">30 U/l</p></td> 
       <td class="custom-top-td acenter" width="38.85%"><p style="text-align:center">5.00 - 40</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="28.61%"><p style="text-align:center">ALAT</p></td> 
       <td class="acenter" width="32.54%"><p style="text-align:center">28 U/L</p></td> 
       <td class="acenter" width="38.85%"><p style="text-align:center">5.00 - 41</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="28.61%"><p style="text-align:center">AP</p></td> 
       <td class="acenter" width="32.54%"><p style="text-align:center">74 U/L</p></td> 
       <td class="acenter" width="38.85%"><p style="text-align:center">40 - 129</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="28.61%"><p style="text-align:center">GGT</p></td> 
       <td class="acenter" width="32.54%"><p style="text-align:center">93 U/L</p></td> 
       <td class="acenter" width="38.85%"><p style="text-align:center">10 - 71</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="28.61%"><p style="text-align:center">Troponin</p></td> 
       <td class="acenter" width="32.54%"><p style="text-align:center">93.41 pg/mL</p></td> 
       <td class="acenter" width="38.85%"><p style="text-align:center">0 - 14</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="28.61%"><p style="text-align:center">NT pro BNP</p></td> 
       <td class="acenter" width="32.54%"><p style="text-align:center">191 pg/mL</p></td> 
       <td class="acenter" width="38.85%"><p style="text-align:center">0 - 125</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="28.61%"><p style="text-align:center">CRP</p></td> 
       <td class="acenter" width="32.54%"><p style="text-align:center">14.2 mg/L</p></td> 
       <td class="acenter" width="38.85%"><p style="text-align:center">0 - 5</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="28.61%"><p style="text-align:center">Creatinine</p></td> 
       <td class="acenter" width="32.54%"><p style="text-align:center">102 µmol/l</p></td> 
       <td class="acenter" width="38.85%"><p style="text-align:center">59 - 104</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="28.61%"><p style="text-align:center">MDRD</p></td> 
       <td class="acenter" width="32.54%"><p style="text-align:center">64.01 ml/min/1.73m<sup>2</sup></p></td> 
       <td class="acenter" width="38.85%"><p style="text-align:center"></p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="28.61%"><p style="text-align:center">CKD-EPI</p></td> 
       <td class="acenter" width="32.54%"><p style="text-align:center">67.08 ml/min/1.73m<sup>2</sup></p></td> 
       <td class="acenter" width="38.85%"><p style="text-align:center"></p></td> 
      </tr> 
     </table>
    </table-wrap>
    <p>Hb: Hemoglobin; PLT: Platelets; WBC: White blood cell; PT: Prothrombin rate; ASAT: Aspartate aminotransferase; ALAT: Alanine aminotransferase; GGT: Gamma-glutamyl transpeptidase; AP: Alkaline phosphatase; NT pro BNP: N-terminal pro brain natriuretic peptide; CRP: C reactive protein; MDRD: Modification of diet in renal disease; CKD-EPI: Chronic kidney disease-epidemiology collaboration.</p>
   </sec>
  </sec><sec id="s3">
   <title>3. Discussion</title>
   <p>Regardless of the heart chambers involved, the presence of intra-cardiac thrombi is associated with pulmonary embolism (PE) in 7% of cases, according to an autopsy study published in a Swedish journal. The same study found that the prevalence of PE increases to 37% if the thrombus is in the right atrium. The diagnosis of right heart thrombus (RHT) is often made using transthoracic echocardiography (TTE), although transesophageal echocardiography (TEE) is highly sensitive. However, TEE is not often quickly available and is invasive, particularly in patients who are typically clinically unstable, which gives a major role in TTE <xref ref-type="bibr" rid="scirp.141472-3">
     [3]
    </xref> <xref ref-type="bibr" rid="scirp.141472-4">
     [4]
    </xref>. According to a study published in the European Heart Journal in 1989, echocardiography is considered an essential tool for classifying right heart thrombi. Type A thrombi are serpiginous or worm-like, highly mobile, and associated with a very poor prognosis, which was the case with our patient. Type B thrombi are relatively immobile and have a better prognosis. Type C thrombi are intermediate between the two in terms of mobility and prognosis <xref ref-type="bibr" rid="scirp.141472-5">
     [5]
    </xref>.</p>
   <p>Although technological advances have made it possible to diagnose right atrial thrombi, treatment remains a challenge worldwide. Anticoagulation, thrombolysis, surgical embolectomy, and percutaneous retrieval techniques are the main treatment options currently available. Despite their proven efficacy in managing thromboembolic diseases, their use in RAT-associated pulmonary embolism (PE) remains perplexing and ambiguous due to the high mortality rate. However, some of these therapeutic options demonstrate superior efficacy compared to others. Fibrinolysis and surgical thrombectomy are associated with a significant reduction in mortality rates in cases of pulmonary embolism associated with RAT. Sometimes, both therapies are sequentially employed, but outcomes are not consistently positive, as cases of death still occur. This was evident in our case, where we initiated treatment with heparin therapy followed by thrombolysis. These variations in therapeutic approaches highlight the lack of international standardized consensus in the management of PE associated with RAT <xref ref-type="bibr" rid="scirp.141472-1">
     [1]
    </xref> <xref ref-type="bibr" rid="scirp.141472-5">
     [5]
    </xref>-<xref ref-type="bibr" rid="scirp.141472-8">
     [8]
    </xref>. Athappan et al. found that initial anticoagulation treatment was unsuccessful in 39.4% of cases, justifying the consideration of thrombolytics as a secondary intervention. Mortality rates are approximately 90% in untreated patients, which decrease to 18.3% with thrombolysis-based treatment and further to 13.9% with surgical intervention, according to the same meta-analysis. Thrombolysis also plays a crucial role, showing superior outcomes in hemodynamically unstable patients compared to surgical embolectomy <xref ref-type="bibr" rid="scirp.141472-9">
     [9]
    </xref>. A single-agent anticoagulation therapy was followed by pulmonary and cardiovascular complications in the case described by Rai et al. This prompts consideration that this therapeutic option may not be the optimal first-line treatment for all patients with right heart thrombus (RHT), even when they are hemodynamically stable or lack other signs of severity associated with PE in the presence of RAT <xref ref-type="bibr" rid="scirp.141472-10">
     [10]
    </xref> <xref ref-type="bibr" rid="scirp.141472-11">
     [11]
    </xref>. The current research projects are emphasizing using catheter-directed-thrombectomy and results are evidently remarkable <xref ref-type="bibr" rid="scirp.141472-12">
     [12]
    </xref>-<xref ref-type="bibr" rid="scirp.141472-14">
     [14]
    </xref>.</p>
  </sec><sec id="s4">
   <title>4. Conclusion</title>
   <p>Right atrium thrombus is commonly associated with massive PE, presenting a significant challenge in modern medicine due to the lack of clear guidelines for its management. Research should prioritize rapid detection and early intervention because prognosis remains uncertain in many cases. Although thrombolysis and surgical approaches have shown promise in reducing mortality rates, they are still insufficient to provide definitive guidance to healthcare providers for treating patients with RAT.</p>
  </sec><sec id="s5">
   <title>Abbreviations List</title>
   <table class="MsoTableGrid custom-table" border="0" cellspacing="0" cellpadding="0"> 
    <tr> 
     <td class="aleft" width="15.38%"><p style="text-align:left">CTPA</p></td> 
     <td class="aleft" width="85.05%"><p style="text-align:left">Computed Tomography Pulmonary Angiogram</p></td> 
    </tr> 
    <tr> 
     <td class="aleft" width="15.38%"><p style="text-align:left">IU</p></td> 
     <td class="aleft" width="85.05%"><p style="text-align:left">International Unit</p></td> 
    </tr> 
    <tr> 
     <td class="aleft" width="15.38%"><p style="text-align:left">PE</p></td> 
     <td class="aleft" width="85.05%"><p style="text-align:left">Pulmonary Embolism</p></td> 
    </tr> 
    <tr> 
     <td class="aleft" width="15.38%"><p style="text-align:left">RAT</p></td> 
     <td class="aleft" width="85.05%"><p style="text-align:left">Right Atrium Thrombus</p></td> 
    </tr> 
    <tr> 
     <td class="aleft" width="15.38%"><p style="text-align:left">RHT</p></td> 
     <td class="aleft" width="85.05%"><p style="text-align:left">Right Heart Thrombus</p></td> 
    </tr> 
    <tr> 
     <td class="aleft" width="15.38%"><p style="text-align:left">TTE</p></td> 
     <td class="aleft" width="85.05%"><p style="text-align:left">Transthoracic Echocardiography</p></td> 
    </tr> 
    <tr> 
     <td class="aleft" width="15.38%"><p style="text-align:left">TEE</p></td> 
     <td class="aleft" width="85.05%"><p style="text-align:left">Transesophageal Echocardiography</p></td> 
    </tr> 
   </table>
  </sec><sec id="s6">
   <title>Appendix: Take Home Messages</title>
   <p>1) Regardless of the presence of severe hemodynamic signs, a right atrial serpiginous thrombus is associated with pulmonary embolism, which often carries a very poor prognosis.</p>
   <p>2) Although thrombolysis is typically indicated in cases of hemodynamic failure in PE, its use in RAT associated with PE patients can improve survival chances and especially bearing in mind that it is also reasonable to consider a surgical embolectomy.</p>
  </sec>
 </body><back>
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