<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article PUBLIC "-//NLM//DTD Journal Publishing DTD v3.0 20080202//EN" "http://dtd.nlm.nih.gov/publishing/3.0/journalpublishing3.dtd">
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="3.0" xml:lang="en" article-type="research article">
 <front>
  <journal-meta>
   <journal-id journal-id-type="publisher-id">
    ojog
   </journal-id>
   <journal-title-group>
    <journal-title>
     Open Journal of Obstetrics and Gynecology
    </journal-title>
   </journal-title-group>
   <issn pub-type="epub">
    2160-8792
   </issn>
   <issn publication-format="print">
    2160-8806
   </issn>
   <publisher>
    <publisher-name>
     Scientific Research Publishing
    </publisher-name>
   </publisher>
  </journal-meta>
  <article-meta>
   <article-id pub-id-type="doi">
    10.4236/ojog.2025.151013
   </article-id>
   <article-id pub-id-type="publisher-id">
    ojog-140327
   </article-id>
   <article-categories>
    <subj-group subj-group-type="heading">
     <subject>
      Articles
     </subject>
    </subj-group>
    <subj-group subj-group-type="Discipline-v2">
     <subject>
      Medicine 
     </subject>
     <subject>
       Healthcare
     </subject>
    </subj-group>
   </article-categories>
   <title-group>
    Epidemiological and Clinical Aspects of Obstetric Fistulas Managed in Six Health Structures in the Central African Republic
   </title-group>
   <contrib-group>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Roch
      </surname>
      <given-names>
       M’Betid-Degana
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff1"> 
      <sup>1</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Gilles-Davy
      </surname>
      <given-names>
       Kossa-Ko-Ouakoua
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff2"> 
      <sup>2</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Saturnin
      </surname>
      <given-names>
       Heya-Imbatia
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff1"> 
      <sup>1</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Georges Crépin
      </surname>
      <given-names>
       Beyam-Yobima
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff1"> 
      <sup>1</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Martial
      </surname>
      <given-names>
       Mbida
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff1"> 
      <sup>1</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Sabrina
      </surname>
      <given-names>
       Ouapou
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff1"> 
      <sup>1</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Géniva Gracelia Vanciane
      </surname>
      <given-names>
       M’Betid-Degana
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff3"> 
      <sup>3</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Serge
      </surname>
      <given-names>
       Ndakala
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff4"> 
      <sup>4</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Christine
      </surname>
      <given-names>
       Amisi
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff5"> 
      <sup>5</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Eugène
      </surname>
      <given-names>
       Serdouma
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff1"> 
      <sup>1</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Norbert Richard
      </surname>
      <given-names>
       Ngbale
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff6"> 
      <sup>6</sup>
     </xref>
    </contrib>
    <contrib contrib-type="author" xlink:type="simple">
     <name name-style="western">
      <surname>
       Abdoulaye
      </surname>
      <given-names>
       Sepou
      </given-names>
     </name> 
     <xref ref-type="aff" rid="aff6"> 
      <sup>6</sup>
     </xref>
    </contrib>
   </contrib-group> 
   <aff id="aff1">
    <addr-line>
     aDepartment of Gynecology and Obstetric, University Hospital Center of the Sino-Central African Friendship, Bangui, Central African Republic
    </addr-line> 
   </aff> 
   <aff id="aff2">
    <addr-line>
     aDepartment of Gynecology and Obstetric, Camp Henri IZAMO Hospital (National Gendarmerie), Bangui, Central African Republic
    </addr-line> 
   </aff> 
   <aff id="aff3">
    <addr-line>
     aFaculty of Health Sciences, University of Bangui, Bangui, Central African Republic
    </addr-line> 
   </aff> 
   <aff id="aff4">
    <addr-line>
     aDepartment of Surgery, University Hospital Center of the Sino-Central African Friendship, Bangui, Central African Republic
    </addr-line> 
   </aff> 
   <aff id="aff5">
    <addr-line>
     aPanzi Foundation, Bukavu, Democratic Republic of Congo
    </addr-line> 
   </aff> 
   <aff id="aff6">
    <addr-line>
     aDepartment of Gynaecology and Obstetric, University Hospital Center Community, Bangui, Central African Republic
    </addr-line> 
   </aff> 
   <pub-date pub-type="epub">
    <day>
     06
    </day> 
    <month>
     01
    </month>
    <year>
     2025
    </year>
   </pub-date> 
   <volume>
    15
   </volume> 
   <issue>
    01
   </issue>
   <fpage>
    138
   </fpage>
   <lpage>
    146
   </lpage>
   <history>
    <date date-type="received">
     <day>
      3,
     </day>
     <month>
      December
     </month>
     <year>
      2024
     </year>
    </date>
    <date date-type="published">
     <day>
      24,
     </day>
     <month>
      December
     </month>
     <year>
      2024
     </year> 
    </date> 
    <date date-type="accepted">
     <day>
      24,
     </day>
     <month>
      January
     </month>
     <year>
      2025
     </year> 
    </date>
   </history>
   <permissions>
    <copyright-statement>
     © Copyright 2014 by authors and Scientific Research Publishing Inc. 
    </copyright-statement>
    <copyright-year>
     2014
    </copyright-year>
    <license>
     <license-p>
      This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/
     </license-p>
    </license>
   </permissions>
   <abstract>
    <b>Introduction: </b>Obstetric Fistulas (OF) constitute a major public health problem in developing countries in general and in Central African Republic (CAR) in particular because of its numerous consequences. The objective of this work is to contribute to the management of OF cases in CAR. 
    <b>Patients and </b>
    <b>Methods</b>
    <b>:</b> This was a retrospective, descriptive and analytical study, including data from several OF care services. The study included 245 cases of OF, operated on from 2009 to 2018. The parameters studied were maternal and obstetrical data, sociodemographic data, the specific characteristics of the fistulas as well as the modalities and outcome of surgical treatment. The data collected came from six (6) OF surgical repair campaigns organized by the Ministry of Health and Population with the support of UNFPA. 
    <b>Results:</b> We recorded 245 patients, representing a prevalence of 0.77% of OF per year. Among these patients, almost half (45.3%) were treated at the Sino-Central African Friendship University Hospital Center (CHUASC). The average age of the patients was 30 years (range 14 to 78 years). They were unschooled (53.9%) and primigravidas (35%). The fistulas had an average duration of evolution of 7.58 years. They were vesicovaginal in 25.3%. Types V and I dominated in 17.4% and 9.2%, respectively. In 85.9% of cases, fistulorrhaphy was performed, half of which (50.2%) via the upper route. The cure rate was 83.3%. Note that our study reveals statistically significant links between the evolution after surgery with age (p = 0.04 &lt; 0.05) and the level of education (p = 0.01 &lt; 0.05). 
    <b>Conclusion:</b> OF mainly affected women of childbearing age, uneducated, primiparous. Vesicovaginal fistula was the frequently encountered type and was manifested by urine loss clinically with a positive methylene blue test.
   </abstract>
   <kwd-group> 
    <kwd>
     Obstetric Fistulas
    </kwd> 
    <kwd>
      Epidemiology
    </kwd> 
    <kwd>
      Treatment
    </kwd> 
    <kwd>
      Central African Republic
    </kwd>
   </kwd-group>
  </article-meta>
 </front>
 <body>
  <sec id="s1">
   <title>1. Introduction</title>
   <p>Obstetric fistulas (OF) are defined as an acquired communication between the vagina and neighboring organs occurring during a prolonged or obstructed delivery (mechanical or dynamic) resulting in a permanent loss of urine and/or feces through the vagina <xref ref-type="bibr" rid="scirp.140327-1">
     [1]
    </xref>. According to the World Health Organization (WHO), OF affect more than two-million women worldwide, the majority of whom live in sub-Saharan Africa (including CAR) and Southeast Asia and constitute a major public health problem due, among other things, to its social consequences, represented by the exclusion of fistula patients due to permanent loss of urine and/or feces <xref ref-type="bibr" rid="scirp.140327-2">
     [2]
    </xref>. A study carried out on urogenital fistulas in Bangui (RCA) found that 86% of these are of obstetric origin <xref ref-type="bibr" rid="scirp.140327-3">
     [3]
    </xref>. The United Nations Population Fund (UNFPA) has financed several campaigns for the treatment of this condition which brought together patients from both urban and rural areas <xref ref-type="bibr" rid="scirp.140327-4">
     [4]
    </xref>-<xref ref-type="bibr" rid="scirp.140327-6">
     [6]
    </xref>. We therefore proposed to carry out this study in order to address the epidemiological, anthropological, clinical and therapeutic aspects based on the files of the patients treated with the aim of contributing to reducing the cases of OF in the CAR.</p>
  </sec><sec id="s2">
   <title>2. Patients and Methods</title>
   <p>The study was carried out in six (06) health facilities in the CAR:</p>
   <p>This was a retrospective, descriptive and analytical study covering OF cases treated from January 2009 to January 2018, a period of nine (09) years in the aforementioned health facilities. The study population consists of fistula patients treated and followed at these centers. All patients with vesicovaginal fistulas (VVF) of obstetric origin treated and followed up in the selected sites and having complete files were included. On the other hand, all patients presenting a no-obstetric fistula (iatrogenic, pathological); VVF lost to follow-up and VVF cases with unusable records were not included in our study.</p>
   <p>After obtaining the various authorizations (Deanship of the Faculty of Health Sciences of the University of Bangui, different chief doctors of the health facilities concerned), the data was collected using pre-established survey sheets in the files and registers of patients with OF (operating room registers and department registers in which the cases are recorded). The sampling was exhaustive. Anonymity was requested. Data entry and analysis were carried out using Epi Info version 7 software. The statistical test used was Chi2 with a significance threshold of p = 0.05.</p>
  </sec><sec id="s3">
   <title>3. Results</title>
   <p>In total, two hundred and forty-five (245) cases of OF were recorded.</p>
   <sec id="s3_1">
    <title>3.1. OF Repair Centers</title>
    <p>Most cases (111 or 45.3%) were treated at the Friendship University Hospital Center (<xref ref-type="table" rid="table1">
      Table 1
     </xref>).</p>
    <table-wrap id="table1">
     <label>
      <xref ref-type="table" rid="table1">
       Table 1
      </xref></label>
     <caption>
      <title>
       <xref ref-type="bibr" rid="scirp.140327-"></xref>Table 1. Distribution of patients according OF repair centers.</title>
     </caption>
     <table class="MsoTableGrid custom-table" border="0" cellspacing="0" cellpadding="0"> 
      <tr> 
       <td class="custom-bottom-td custom-top-td acenter" width="55.46%"><p style="text-align:center">OF repair centers</p></td> 
       <td class="custom-bottom-td custom-top-td acenter"><p style="text-align:center">Numbers (n)</p></td> 
       <td class="custom-bottom-td custom-top-td acenter"><p style="text-align:center">Percentage (%)</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td acenter" width="55.46%"><p style="text-align:center">Friendship University Hospital Center</p></td> 
       <td class="custom-top-td acenter"><p style="text-align:center">111</p></td> 
       <td class="custom-top-td acenter"><p style="text-align:center">45.3</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="55.46%"><p style="text-align:center">Regional University Hospital of Bambari</p></td> 
       <td class="acenter"><p style="text-align:center">38</p></td> 
       <td class="acenter"><p style="text-align:center">15.5</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="55.46%"><p style="text-align:center">Sibut District Hospital</p></td> 
       <td class="acenter"><p style="text-align:center">16</p></td> 
       <td class="acenter"><p style="text-align:center">6.5</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="55.46%"><p style="text-align:center">Kaga-Bandoro District Hospital</p></td> 
       <td class="acenter"><p style="text-align:center">23</p></td> 
       <td class="acenter"><p style="text-align:center">9.4</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="55.46%"><p style="text-align:center">Mbaïki District Hospital</p></td> 
       <td class="acenter"><p style="text-align:center">40</p></td> 
       <td class="acenter"><p style="text-align:center">16.4</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td acenter" width="55.46%"><p style="text-align:center">Beavers Urban Health Center</p></td> 
       <td class="custom-bottom-td acenter"><p style="text-align:center">17</p></td> 
       <td class="custom-bottom-td acenter"><p style="text-align:center">6.9</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td custom-top-td acenter" width="55.46%"><p style="text-align:center">Total</p></td> 
       <td class="custom-bottom-td custom-top-td acenter"><p style="text-align:center">245</p></td> 
       <td class="custom-bottom-td custom-top-td acenter"><p style="text-align:center">100.0</p></td> 
      </tr> 
     </table>
    </table-wrap>
   </sec>
   <sec id="s3_2">
    <title>3.2. Age Group</title>
    <p>There were more patients aged 15 - 24 and 25 - 34. The average age was around 31 years old (<xref ref-type="table" rid="table2">
      Table 2
     </xref>).</p>
    <table-wrap id="table2">
     <label>
      <xref ref-type="table" rid="table2">
       Table 2
      </xref></label>
     <caption>
      <title>
       <xref ref-type="bibr" rid="scirp.140327-"></xref>Table 2. Distribution of cases according to age group.</title>
     </caption>
     <table class="MsoTableGrid custom-table" border="0" cellspacing="0" cellpadding="0"> 
      <tr> 
       <td class="custom-bottom-td custom-top-td acenter" width="33.33%"><p style="text-align:center">Age group</p></td> 
       <td class="custom-bottom-td custom-top-td acenter" width="33.33%"><p style="text-align:center">Numbers (n)</p></td> 
       <td class="custom-bottom-td custom-top-td acenter" width="33.34%"><p style="text-align:center">Percentage (%)</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td acenter" width="33.33%"><p style="text-align:center">≤14</p></td> 
       <td class="custom-top-td acenter" width="33.33%"><p style="text-align:center">1</p></td> 
       <td class="custom-top-td acenter" width="33.34%"><p style="text-align:center">0.4</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="33.33%"><p style="text-align:center">[15 - 24]</p></td> 
       <td class="acenter" width="33.33%"><p style="text-align:center">79</p></td> 
       <td class="acenter" width="33.34%"><p style="text-align:center">32.2</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="33.33%"><p style="text-align:center">[25 - 34]</p></td> 
       <td class="acenter" width="33.33%"><p style="text-align:center">79</p></td> 
       <td class="acenter" width="33.34%"><p style="text-align:center">32.2</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="33.33%"><p style="text-align:center">[35 - 44]</p></td> 
       <td class="acenter" width="33.33%"><p style="text-align:center">57</p></td> 
       <td class="acenter" width="33.34%"><p style="text-align:center">23.3</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="33.33%"><p style="text-align:center">[45 - 54]</p></td> 
       <td class="acenter" width="33.33%"><p style="text-align:center">20</p></td> 
       <td class="acenter" width="33.34%"><p style="text-align:center">8.2</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td acenter" width="33.33%"><p style="text-align:center">≥ 55</p></td> 
       <td class="custom-bottom-td acenter" width="33.33%"><p style="text-align:center">9</p></td> 
       <td class="custom-bottom-td acenter" width="33.34%"><p style="text-align:center">3.7</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td custom-top-td acenter" width="33.33%"><p style="text-align:center">Total</p></td> 
       <td class="custom-bottom-td custom-top-td acenter" width="33.33%"><p style="text-align:center">245</p></td> 
       <td class="custom-bottom-td custom-top-td acenter" width="33.34%"><p style="text-align:center">100.0</p></td> 
      </tr> 
     </table>
    </table-wrap>
   </sec>
   <sec id="s3_3">
    <title>3.3. Level of Education</title>
    <p>The majority of patients (53.9%) were illiterate (<xref ref-type="fig" rid="fig1">
      Figure 1
     </xref>).</p>
    <fig id="fig1" position="float">
     <label>Figure 1</label>
     <caption>
      <title>Figure 1. Distribution of patients according to level of education.</title>
     </caption>
     <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/1433552-rId17.jpeg?20250127015337" />
    </fig>
   </sec>
   <sec id="s3_4">
    <title>3.4. Parity</title>
    <p>First-time mothers were the most represented (38%) (<xref ref-type="fig" rid="fig2">
      Figure 2
     </xref>).</p>
    <fig id="fig2" position="float">
     <label>Figure 2</label>
     <caption>
      <title>Figure 2. Distribution of patients according to parity.</title>
     </caption>
     <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/1433552-rId18.jpeg?20250127015337" />
    </fig>
   </sec>
   <sec id="s3_5">
    <title>3.5. Prenatal Fellow-Up</title>
    <p>Most patients (73.1%) had made fewer than four contacts during prenatal follow-up (<xref ref-type="table" rid="table3">
      Table 3
     </xref>).</p>
   </sec>
   <sec id="s3_6">
    <title>3.6. Duration of Work</title>
    <p>The average working time was 3.16 days or approximately 75 hours (<xref ref-type="table" rid="table4">
      Table 4
     </xref>).</p>
    <table-wrap id="table3">
     <label>
      <xref ref-type="table" rid="table3">
       Table 3
      </xref></label>
     <caption>
      <title>
       <xref ref-type="bibr" rid="scirp.140327-"></xref>Table 3. Distribution of patients according to the number of contacts made during prenatal follow-up.</title>
     </caption>
     <table class="MsoTableGrid custom-table" border="0" cellspacing="0" cellpadding="0"> 
      <tr> 
       <td class="custom-bottom-td custom-top-td acenter" width="33.33%"><p style="text-align:center">Number of contacts</p></td> 
       <td class="custom-bottom-td custom-top-td acenter" width="33.33%"><p style="text-align:center">Numbers (n)</p></td> 
       <td class="custom-bottom-td custom-top-td acenter" width="33.34%"><p style="text-align:center">Percentage (%)</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td acenter" width="33.33%"><p style="text-align:center">&lt;4</p></td> 
       <td class="custom-top-td acenter" width="33.33%"><p style="text-align:center">179</p></td> 
       <td class="custom-top-td acenter" width="33.34%"><p style="text-align:center">73.1</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td acenter" width="33.33%"><p style="text-align:center">≥4</p></td> 
       <td class="custom-bottom-td acenter" width="33.33%"><p style="text-align:center">66</p></td> 
       <td class="custom-bottom-td acenter" width="33.34%"><p style="text-align:center">26.9</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td custom-top-td acenter" width="33.33%"><p style="text-align:center">Total</p></td> 
       <td class="custom-bottom-td custom-top-td acenter" width="33.33%"><p style="text-align:center">245</p></td> 
       <td class="custom-bottom-td custom-top-td acenter" width="33.34%"><p style="text-align:center">100.0</p></td> 
      </tr> 
     </table>
    </table-wrap>
    <table-wrap id="table4">
     <label>
      <xref ref-type="table" rid="table4">
       Table 4
      </xref></label>
     <caption>
      <title>
       <xref ref-type="bibr" rid="scirp.140327-"></xref>Table 4. Distribution of patients according to approximate duration of labor (in hours).</title>
     </caption>
     <table class="MsoTableGrid custom-table" border="0" cellspacing="0" cellpadding="0"> 
      <tr> 
       <td class="custom-bottom-td custom-top-td acenter" width="33.33%"><p style="text-align:center">Hours</p></td> 
       <td class="custom-bottom-td custom-top-td acenter" width="33.33%"><p style="text-align:center">Numbers (n)</p></td> 
       <td class="custom-bottom-td custom-top-td acenter" width="33.34%"><p style="text-align:center">Percentage (%)</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td acenter" width="33.33%"><p style="text-align:center">[12 - 23]</p></td> 
       <td class="custom-top-td acenter" width="33.33%"><p style="text-align:center">4</p></td> 
       <td class="custom-top-td acenter" width="33.34%"><p style="text-align:center">1.6</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="33.33%"><p style="text-align:center">[24 - 47]</p></td> 
       <td class="acenter" width="33.33%"><p style="text-align:center">71</p></td> 
       <td class="acenter" width="33.34%"><p style="text-align:center">29.0</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="33.33%"><p style="text-align:center">[48 - 71]</p></td> 
       <td class="acenter" width="33.33%"><p style="text-align:center">56</p></td> 
       <td class="acenter" width="33.34%"><p style="text-align:center">22.9</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td acenter" width="33.33%"><p style="text-align:center">≥72</p></td> 
       <td class="custom-bottom-td acenter" width="33.33%"><p style="text-align:center">114</p></td> 
       <td class="custom-bottom-td acenter" width="33.34%"><p style="text-align:center">46.5</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td custom-top-td acenter" width="33.33%"><p style="text-align:center">Total</p></td> 
       <td class="custom-bottom-td custom-top-td acenter" width="33.33%"><p style="text-align:center">245</p></td> 
       <td class="custom-bottom-td custom-top-td acenter" width="33.34%"><p style="text-align:center">100.0</p></td> 
      </tr> 
     </table>
    </table-wrap>
    <p>The extremes were 0 days and 6 days, the maximum frequency corresponded to 3 - 4 days in 46.5% of cases.</p>
   </sec>
   <sec id="s3_7">
    <title>3.7. Mode of Delivery</title>
    <p>Most patients had delivered vaginally (64%) (<xref ref-type="fig" rid="fig3">
      Figure 3
     </xref>).</p>
    <fig id="fig3" position="float">
     <label>Figure 3</label>
     <caption>
      <title>Figure 3. Distribution of patients according to the mode of delivery of the causal pregnancy.</title>
     </caption>
     <graphic mimetype="image" position="float" xlink:type="simple" xlink:href="https://html.scirp.org/file/1433552-rId19.jpeg?20250127015337" />
    </fig>
   </sec>
   <sec id="s3_8">
    <title>3.8. Types of OF</title>
    <p>The fistulas were of vesico-vaginal location in 25.3% on a soft vagina in 23.5% (<xref ref-type="table" rid="table5">
      Table 5
     </xref>).</p>
    <p>Types V and I dominated in 17.4% and 9.2%, respectively.</p>
   </sec>
   <sec id="s3_9">
    <title>3.9. Approaches</title>
    <p>In the majority of cases (50.2%), the fistula was treated via the upper route (<xref ref-type="table" rid="table6">
      Table 6
     </xref>).</p>
    <table-wrap id="table5">
     <label>
      <xref ref-type="table" rid="table5">
       Table 5
      </xref></label>
     <caption>
      <title>
       <xref ref-type="bibr" rid="scirp.140327-"></xref>Table 5. Distribution of patients according to types of OF.</title>
     </caption>
     <table class="MsoTableGrid custom-table" border="0" cellspacing="0" cellpadding="0"> 
      <tr> 
       <td rowspan="2" class="custom-top-td acenter" width="65.81%"><p style="text-align:center">Classification of fistula</p></td> 
       <td class="custom-bottom-td custom-top-td acenter" width="34.19%" colspan="3"><p style="text-align:center">Answers</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td custom-top-td acenter" width="17.09%"><p style="text-align:center">Numbers</p></td> 
       <td class="custom-top-td acenter" width="17.09%" colspan="2"><p style="text-align:center">Percentage</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td aleft" width="65.81%"><p style="text-align:left">Fistula on soft vagina</p></td> 
       <td class="custom-top-td acenter" width="17.05%"><p style="text-align:center">164</p></td> 
       <td class="custom-top-td acenter" width="17.05%"><p style="text-align:center">23.5%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="65.81%"><p style="text-align:left">Fistula on sclerotic vagina</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">55</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">7.9%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="65.81%"><p style="text-align:left">Fistula associated with perineal tear (1st, 2nd, 3rd degree)</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">8</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">1.1%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="65.81%"><p style="text-align:left">Type I: fistula of the vesico-vaginal septum</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">64</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">9.2%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="65.81%"><p style="text-align:left">Type II: vesico-cervico-urethral fistula</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">6</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">0.9%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="65.81%"><p style="text-align:left">Type IIa: without destruction of the urethra</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">6</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">0.9%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="65.81%"><p style="text-align:left">Type IIb: cervico-urethro-vaginal fistula</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">2</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">0.3%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="65.81%"><p style="text-align:left">Type IIab: partial cervico-urethral desinertion</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">7</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">1.0%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="65.81%"><p style="text-align:left">Type IIc: with destruction of the urethra</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">4</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">0.6%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="65.81%"><p style="text-align:left">Type III: trigono-cervico-uterovaginal fistulas</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">28</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">4.0%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="65.81%"><p style="text-align:left">Type IV: complex fistulas</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">22</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">3,2%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="65.81%"><p style="text-align:left">Type V: high fistulas (retro-trigonal)</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">121</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">17.4%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="65.81%"><p style="text-align:left">Vesico-vaginal</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">176</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">25.3%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="65.81%"><p style="text-align:left">Vesico-cervico-uterine</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">15</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">2.2%</p></td> 
      </tr> 
      <tr> 
       <td class="aleft" width="65.81%"><p style="text-align:left">Vesico-uterine</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">11</p></td> 
       <td class="acenter" width="17.05%"><p style="text-align:center">1.6%</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td aleft" width="65.81%"><p style="text-align:left">Vaginal ureter</p></td> 
       <td class="custom-bottom-td acenter" width="17.05%"><p style="text-align:center">8</p></td> 
       <td class="custom-bottom-td acenter" width="17.05%"><p style="text-align:center">1.1%</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td custom-top-td acenter" width="65.81%"><p style="text-align:center">Total</p></td> 
       <td class="custom-bottom-td custom-top-td acenter" width="17.09%"><p style="text-align:center">697</p></td> 
       <td class="custom-bottom-td acenter" width="17.09%" colspan="2"><p style="text-align:center">100.0%</p></td> 
      </tr> 
     </table>
    </table-wrap>
    <table-wrap id="table6">
     <label>
      <xref ref-type="table" rid="table6">
       Table 6
      </xref></label>
     <caption>
      <title>
       <xref ref-type="bibr" rid="scirp.140327-"></xref>Table 6. Distribution of patients according to surgical approach.</title>
     </caption>
     <table class="MsoTableGrid custom-table" border="0" cellspacing="0" cellpadding="0"> 
      <tr> 
       <td class="custom-bottom-td custom-top-td acenter" width="33.44%" colspan="2"><p style="text-align:center">Surgical approach</p></td> 
       <td class="custom-bottom-td custom-top-td acenter" width="33.46%" colspan="2"><p style="text-align:center">Number (n)</p></td> 
       <td class="custom-top-td acenter" width="33.10%"><p style="text-align:center">Percentage (%)</p></td> 
      </tr> 
      <tr> 
       <td class="custom-top-td acenter" width="33.32%"><p style="text-align:center">Low</p></td> 
       <td class="custom-top-td acenter" width="33.34%" colspan="2"><p style="text-align:center">93</p></td> 
       <td class="custom-top-td acenter" width="33.34%" colspan="2"><p style="text-align:center">38.0</p></td> 
      </tr> 
      <tr> 
       <td class="acenter" width="33.32%"><p style="text-align:center">High</p></td> 
       <td class="acenter" width="33.34%" colspan="2"><p style="text-align:center">123</p></td> 
       <td class="acenter" width="33.34%" colspan="2"><p style="text-align:center">50.2</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td acenter" width="33.32%"><p style="text-align:center">Mixed</p></td> 
       <td class="custom-bottom-td acenter" width="33.34%" colspan="2"><p style="text-align:center">29</p></td> 
       <td class="custom-bottom-td acenter" width="33.34%" colspan="2"><p style="text-align:center">11.8</p></td> 
      </tr> 
      <tr> 
       <td class="custom-bottom-td custom-top-td acenter" width="33.32%"><p style="text-align:center">Total</p></td> 
       <td class="custom-bottom-td custom-top-td acenter" width="33.34%" colspan="2"><p style="text-align:center">245</p></td> 
       <td class="custom-bottom-td custom-top-td acenter" width="33.34%" colspan="2"><p style="text-align:center">100.0</p></td> 
      </tr> 
     </table>
    </table-wrap>
   </sec>
  </sec><sec id="s4">
   <title>4. Discussion</title>
   <sec id="s4_1">
    <title>4.1. OF Repair Centers</title>
    <p>All areas of the CAR were represented: urban and rural. Bangui, an urban area, represents 52.2% (CHU de l’Amitié and Castors Health Center) and rural areas, 47.8%. This rate shows that the majority of fistulas are repaired in Bangui, where medical infrastructure is less poor, security relatively acceptable and qualified personnel available (gynecologists, urologists, anesthesiologists).</p>
   </sec>
   <sec id="s4_2">
    <title>4.2. Level Education</title>
    <p>Educational level is a direct reflection of occupation and socio-economic level <xref ref-type="bibr" rid="scirp.140327-7">
      [7]
     </xref>. Indeed, 53.9% of our patients were illiterate and therefore unemployed with low income <xref ref-type="bibr" rid="scirp.140327-8">
      [8]
     </xref>. This lack of financial means for treatment in the event of a health problem would be the cause of prolonged working hours, thus causing OF. Our results are superimposable to those of Sheilla MY et al. Bangui <xref ref-type="bibr" rid="scirp.140327-9">
      [9]
     </xref> who found that 70.9% of patients were illiterate and 85.5% carried out household activities.</p>
   </sec>
   <sec id="s4_3">
    <title>4.3. Parity</title>
    <p>In our series, fistula occurred much more in primiparous women (38%) then in pauciparous women (30%). These results can be superimposed on certain data from the literature. Sanda in Niger also reports a predominance of first-time mothers (67.3%) without children among OF carriers <xref ref-type="bibr" rid="scirp.140327-10">
      [10]
     </xref> <xref ref-type="bibr" rid="scirp.140327-11">
      [11]
     </xref>. The same observation was made by Ouattara in Bamako in Mali, including 76.4% of carriers of vesico-vaginal fistulas were primiparous <xref ref-type="bibr" rid="scirp.140327-12">
      [12]
     </xref>.</p>
   </sec>
   <sec id="s4_4">
    <title>4.4. Prenatal Follow-Up and Duration of Labor</title>
    <p>The majority of patients (73.1%) had made fewer than four contacts during pregnancy compared to 26.9% of patients who had not followed a prenatal consultation. The average duration of work was 3.16 days or approximately 75 hours. The extremes were 0 days and 6 days, the maximum frequency corresponded to 3 - 4 days in 46.5% of cases. This poor performance of prenatal monitoring coupled with the poor quality linked to the absence of qualified personnel would be the cause of prolonged labor and other negative consequences due to lack of last contact during which the prognostic delivery plan of the child is established. In some studies, this average duration is similar, varying between 2.5 and 4 days <xref ref-type="bibr" rid="scirp.140327-13">
      [13]
     </xref>-<xref ref-type="bibr" rid="scirp.140327-15">
      [15]
     </xref>.</p>
   </sec>
   <sec id="s4_5">
    <title>4.5. Mode of Delivery</title>
    <p>In relation to the mode of delivery, cesarean section was the most incriminated mode in our series with 64% of cases or 157 patients. The same observation was made following a previous study carried out in Bangui in the Central African Republic in 2005 by Nguembi et al. which reports the occurrence of OF caused by technical errors during cesarean section <xref ref-type="bibr" rid="scirp.140327-16">
      [16]
     </xref>. During the second conference of fistula surgeons in November 2009 in Yaoundé, the iatrogenic nature of obstetric fistulas was the subject of concern among the speakers <xref ref-type="bibr" rid="scirp.140327-17">
      [17]
     </xref>. Other authors have made the same observation with respectively 57.72% and 54.03% of cesarean sections <xref ref-type="bibr" rid="scirp.140327-18">
      [18]
     </xref> <xref ref-type="bibr" rid="scirp.140327-19">
      [19]
     </xref>. In our study, the high proportion of iatrogenic OF could be explained on the one hand by the insufficiency of the qualified personnel throughout the territory with a high concentration of competent personnel in urban areas <xref ref-type="bibr" rid="scirp.140327-20">
      [20]
     </xref>. On the other hand, the late arrival of parturients in the reference centers after several days of attempts of deliveries constitutes a significant factor in the genesis of fistulas of obstetric origin. Caesarean section being performed for maternal rescue. In health facilities, unqualified medical personnel could assist with acute deliveries but are sometimes unable to detect an obstetric emergency or obstructed labor that could prompt evacuation to a reference center <xref ref-type="bibr" rid="scirp.140327-18">
      [18]
     </xref>.</p>
   </sec>
  </sec><sec id="s5">
   <title>5. Conclusion</title>
   <p>The study carried out six (06) OF treatment sites in the CAR and allowed us to conclude that OF are common in the country and constitute a real public health problem because of its multiple consequences (social, medical, psychological, economic). OF mainly affected women of childbearing age, uneducated, and primiparous. Vesicovaginal fistula was the frequently encountered type and was manifested by urine loss clinically with a positive methylene blue test. Strong social mobilization coupled with broad awareness (community prevention) as well as the practice of good obstetrics will constitute effective measures to reduce the prevalence of OF.</p>
  </sec>
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