A total of 6017 patients were examined, 289 of whom had urological cancer, correspondence to 4.80% of urological pathologies.

The median age of patients was 50.42 years for all urological cancers.

Lower urinary tract disorders (n = 78; 35.29%), complete retention of urine (n = 40; 18.09%), altered general condition (n = 41; 18.56%), elevated PSA (n = 35; 15.84%), renal failure (n = 17; 07.70%), paraplegia (n = 4; 1.81%), pelvic limb edema (n = 6; 2.71%).

Histology Adenocarcinoma in 100% (n = 221) of cases.

PSA rate > 20 ng/ml was 90.04%.

134 cases (60.63%) of which Computed Tomography (n = 43; 19.46%), abdominopelvic ultrasound (n = 16; 7.24%) and standard radiography (n = 75; 33.93%).

Surgical castration was performed in 62.44%, chosen for its low cost.

Cervico-prostatic tumor removing (CPTR) 31.22%, Antiandrogen (A.A).

Castration resistance appeared between 8 and 11 months of age.

Only 3 (1.36%) could afford to continue chemotherapy with second line anti-androgens (Abiraterone Acetate + prednisolone). The hospital mortality of prostate cancer was 16.29%.

Bladder cancer 46 cases, Sex ratio 7/1.

Total hematuria (80.43% = 37), hypogastric mass (26.08% = 12), pyuria lumbar pain (11 = 23.91%). Cystoscopy was performed in all cases. Histology revealed squamous cell carcinoma (n = 41; 89.13%), and (n = 5; 10.87%) urothelial.

Endoscopic resection performed in (n = 14; 30.43%) cases.

Lumbar mass 76.92%, deterioration of general condition 46.15%.

Histology: renal cell carcinoma in 87.13% of cases. Nephrectomy was performed for 8 patients, 3 had tumor-reducing chemotherapy and two others were evacuated in another country for better management.

Chronic wound in 6 cases, large solid bursa in 2 cases and one case of recurrence on the contralateral testicle. A history of cryptorchidism in 4 cases, primary infertility in 3 cases Abdominal and pelvic ultrasound were used to assess the extent of the disease.

Orchiectomy was performed in all cases. Three patients had received chemotherapy.

Prostate cancer epidemiologicaly is the most common urological cancer. In Africa, a metanalysis by Adeloye estimates its incidence at 21.95/100,000 persons [8] . In a previous study in Zinder, the incidence was 37 new cases per year [9] . Diagnosis of prostate cancer has been facilitated in Zinder since the availability of biopsy and histology. These enabled us to record 221 cases of prostate cancer, representing 76.47% of urological cancers diagnosed during the period (Table 1). According to Sharma et al., prostate cancer is the leading men cancer in Africa, with 97,173 cases in 2020 [10] . Although Prostatic Specific Antigen (PSA) measurement paired with digital rectal examination (DRE) remains reliable for screening, prostate cancer is discovered with advanced forms in Africa: the long clinical latency of prostate cancer, the insufficiency of public awareness, and the lack of mass screening could be reasons. This is corroborated by Ondo in Senegal (46.9%), Botcho in Togo (64.39%) and Cissé in Conakry (83.3%), where the majority of patients had consulted a specialist late with metastatic forms [11] [12] [13] . In our series, 44% have metastatic complications. In a meta-analysis by Cassell lower urinary tract symptoms were the main reason for consultation, and the rectal examination was abnormal in 66.67% of cases, while Diallo recorded 68.3% of consultations for urinary disorders [14] [15] .

All these studies confirm the delay in consultation linked to the long latency of this cancer. In the same meta-analysis by Cassell, the Gleason score above 7 was 62.5% [14] . In our serie the proportion of Gleason score superior or seven (7) was supérior to 78% as reported in Table 3. PSA is an important element in screening, and its value above 50 may suggest metastatic cancer. Approximately 70 % had a PSA greater than 50 (Figure 2) and 60.63% of metastases were detected proving the benefits of PSA. Our rate is close to Konan’s in Abidjan (68.23%) [16] .

Treatment modalities were exposed in Table 4. According to guidelines, androgen deprivation is the treatment of metastatic cancer [17] . In most cases in Africa, androgen deprivation is achieved by surgical castration, due to its low cost. Depending on the patient’s means, it may be combined with an anti-androgen. Surgical castration combined with an anti-androgen (Bicalutamide 50 mg; 3 tablets daily) was our main procedure. It was performed in 62.44% of cases for complete androgen deprivation. This rate is close to Diallo’s 68.3%, but far from Ondo’s 100% castration rate in Senegal [11] [15] . Mortality was 16.29%, in line with the assessment of specific mortality for this cancer in the sub-region by Ouattara, Modou, Cissé, Konan and Ouédraogo (19.3%; 34.4%; 28.33%; 16.19%; 15%) respectively [4] [5] [13] [16] [18] .

According to Globocan 2020, bladder cancer is the second most common urological cancer after prostate cancer, with 573,278 new cases and 212,536 deaths. In Africa, a meta-analysis by Adeloye of 22 bladder cancer reports from 15 countries found an overall incidence of 7/100,000 for men and 1.8/100,000 for women. It is more common in North Africa, with an incidence of 10.1/100,000 men, compared with 5/100,000 men in sub-Saharan Africa [1] [19] . The urothelial type is more frequent in the north, while the squamous cell carcinoma is abondant in south of the Sahara, due to the endemic bilharziasis, as discovered by Diao, Younoussa [20] [21] . In this study, bladder cancer accounted for 15.92% of cancers recorded. Our rate is close to Diallo’s in Senegal, Darré’s in Togo and Tela’s in Nigeria with 17.9%, 14.16% and 19.8% respectively [7] [15] [22] . But much lower than that of Ouattara’s in Benin with 33.1%, and Salah’s in Algeria with 60.3% [5] [23] . The main manifestation of bladder cancer was total hematuria (n = 37; 80.43%) in our serie, which was 63% for Diallo, 65.71% for Avakoudjo in Benin and 100% for Zakhama [15] [24] [25] . Cystoscopy was performed and enabled biopsy in all cases. Squamous cell carcinoma accounted for 89.13% (n = 41); this histological type is considered to have a poor prognosis. Endoscopic resection in 14 cases (30.43%), which confirms the processing difficulties in our context

Kidney cancer is an uncommon cancer; we recorded 13 cases in 5 years, representing 4.5% of urological cancers. It represented 13.46% in Diallo’s series, 8.11% in Darre’s, and 8.7% in Salah’s in Algeria [7] [15] [23] . The circumstances of discovery in the majority of cases is evidence of an advanced form often out of reach in our study it was lumbar mass in 76.92%, 65.6% for Tengue in Togo, 54% for Diallo in Senegal [15] [26] . All these studies show that kidney cancer is far from being an incidental finding in Africa, and therefore offers little chance of cure and conservative treatment such as partial nephrectomy, which is widely practised in developed countries. Histological analysis revealed renal cell carcinoma in 87.13% of cases, in line with the findings of Ouédraogo, Darre, Salah and Diallo [4] [7] [15] [23] .

Testicular cancer is an uncommon cancer, as reported in several studies in the sub-region. Ouattara (3 cases/3 years), Ouédraogo (11 cases/10 years), Salah (7 cases/12 years) and Darre (13 cases/20 years). We recorded 9 cases in 5 years [5] [4] [7] [23] . It is mainly diagnosed in young people aged between 17 and 34. In this series, all cases have an advanced stage of the disease. Orchiectomy was performed for all patients, and all were germ cell tumors, whereas Ouédraogo found 72.72% germ cell tumors [4] .