<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article  PUBLIC "-//NLM//DTD Journal Publishing DTD v3.0 20080202//EN" "http://dtd.nlm.nih.gov/publishing/3.0/journalpublishing3.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="3.0" xml:lang="en" article-type="research article"><front><journal-meta><journal-id journal-id-type="publisher-id">JCC</journal-id><journal-title-group><journal-title>Journal of Computer and Communications</journal-title></journal-title-group><issn pub-type="epub">2327-5219</issn><publisher><publisher-name>Scientific Research Publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.4236/jcc.2024.124012</article-id><article-id pub-id-type="publisher-id">JCC-132632</article-id><article-categories><subj-group subj-group-type="heading"><subject>Articles</subject></subj-group><subj-group subj-group-type="Discipline-v2"><subject>Computer Science&amp;Communications</subject></subj-group></article-categories><title-group><article-title>
 
 
  A Multi-Task Deep Learning Framework for Simultaneous Detection of Thoracic Pathology through Image Classification
 
</article-title></title-group><contrib-group><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Nada</surname><given-names>Al Zahrani</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Ramdane</surname><given-names>Hedjar</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Mohamed</surname><given-names>Mekhtiche</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Mohamed</surname><given-names>Bencherif</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Taha</surname><given-names>Al Fakih</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Fattoh</surname><given-names>Al-Qershi</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Muna</surname><given-names>Alrazghan</given-names></name><xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib></contrib-group><aff id="aff3"><addr-line>Department of Software Engineering, College of Computer and Information Sciences, King Saud University, Riyadh, Saudi Arabia</addr-line></aff><aff id="aff2"><addr-line>Department of Information System, College of Computer and Information Sciences, King Saud University, Riyadh, Saudi Arabia</addr-line></aff><aff id="aff1"><addr-line>Department of Computer Engineering, College of Computer and Information Sciences, King Saud University, Riyadh, Saudi Arabia</addr-line></aff><pub-date pub-type="epub"><day>01</day><month>04</month><year>2024</year></pub-date><volume>12</volume><issue>04</issue><fpage>153</fpage><lpage>170</lpage><history><date date-type="received"><day>27,</day>	<month>February</month>	<year>2024</year></date><date date-type="rev-recd"><day>21,</day>	<month>April</month>	<year>2024</year>	</date><date date-type="accepted"><day>24,</day>	<month>April</month>	<year>2024</year></date></history><permissions><copyright-statement>&#169; Copyright  2014 by authors and Scientific Research Publishing Inc. </copyright-statement><copyright-year>2014</copyright-year><license><license-p>This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/</license-p></license></permissions><abstract><p>
 
 
  Thoracic diseases pose significant risks to an individual's chest health and are among the most perilous medical diseases. They can impact either one or both lungs, which leads to a severe impairment of a person&amp;#8217;s ability to breathe normally. Some notable examples of such diseases encompass pneumonia, lung cancer, coronavirus disease 2019 (COVID-19), tuberculosis, and chronic obstructive pulmonary disease (COPD). Consequently, early and precise detection of these diseases is paramount during the diagnostic process. Traditionally, the primary methods employed for the detection involve the use of X-ray imaging or computed tomography (CT) scans. Nevertheless, due to the scarcity of proficient radiologists and the inherent similarities between these diseases, the accuracy of detection can be compromised, leading to imprecise or erroneous results. To address this challenge, scientists have turned to computer-based solutions, aiming for swift and accurate diagnoses. The primary objective of this study is to develop two machine learning models, utilizing single-task and multi-task learning frameworks, to enhance classification accuracy. Within the multi-task learning architecture, two principal approaches exist soft parameter sharing and hard parameter sharing. Consequently, this research adopts a multi-task deep learning approach that leverages CNNs to achieve improved classification performance for the specified tasks. These tasks, focusing on pneumonia and COVID-19, are processed and learned simultaneously within a multi-task model. To assess the effectiveness of the trained model, it is rigorously validated using three different real-world datasets for training and testing.
 
</p></abstract><kwd-group><kwd>Pneumonia</kwd><kwd> Thoracic Pathology</kwd><kwd> COVID-19</kwd><kwd> Deep Learning</kwd><kwd> Multi-Task Learning</kwd></kwd-group></article-meta></front><body><sec id="s1"><title>1. Introduction</title><p>In contemporary scientific research, an emerging and highly regarded subject of exploration involves a specific facet of deep learning known as the multi-task deep learning approach. This innovative technique facilitates the simultaneous training of numerous tasks [<xref ref-type="bibr" rid="scirp.132632-ref1">1</xref>] , ultimately contributing to the enhancement of model classification performance. In this pursuit of excellence, researchers engage in a continuous process of refining and enhancing these models until no further performance improvements are attainable. This article delves into multi-task deep learning paradigms, highlighting their significance and the relentless efforts invested by researchers to improve their applications. The multi-task deep learning can be an effective and fast method to identify and detect COVID-19 through CT scans or X-ray images [<xref ref-type="bibr" rid="scirp.132632-ref2">2</xref>] . Thus, multi-task convolutional neural networks can classify different abnormalities of the chest correctly. Therefore, it is simultaneously capable of detecting COVID-19 and pneumonia using both CT scans and CXR images. It combines the entire available data labels into a single model. It makes it possible to carry out various but connected tasks using only one neural network architecture. Hence, this paradigm makes the use of the convolution layer efficient and improves the performance above the single-task models [<xref ref-type="bibr" rid="scirp.132632-ref3">3</xref>] . Multi-task Learning (MTL) in general, aims to learn multiple tasks together at the same time. This will improve the generalization of the model. MTL can be defined as the optimization of several loss functions in a single model such that shared representation learning can execute related tasks [<xref ref-type="bibr" rid="scirp.132632-ref4">4</xref>] .</p><p>Multi-task learning creates challenges that are absent from single-task learning. Particularly, several tasks may have requirements that contradict each other. In this situation, a phenomenon known as negative transfer or destructive interference occurs when a model’s improved performance on one job degrades the performance of another job. Therefore, a primary objective of MTL techniques is to minimize negative transfer. Splitting data between tasks is a delicate balance to fulfill because so many structures are designed with particular features to decrease the negative transfer, such as task-specific feature spaces as well as attention mechanisms. However, it is really interesting to allow information flow among tasks that result in positive transfer and deterring sharing when it would generate a bad transfer. In our work, the tasks are Pneumonia, COVID-19, and Normal. There are two main types of MTL. It is noted that the Deep Learning MTL techniques that are most used will be described.</p><p>In this study, we have developed a multi-task deep learning framework capable of simultaneously detecting both COVID-19 and pneumonia through image classification tasks. Our contributions encompassed the thorough training of various well-established pre-trained CNN architectures, including VGG-16, InceptionV3, Res-Net-50, and EfficientNetB0, until a notably high level of accuracy in disease detection is achieved. Furthermore, we conducted a comprehensive comparative analysis of these promising CNN architectures, evaluating their respective accuracies.</p></sec><sec id="s2"><title>2. Related Work</title><p>The process of thoracic disease detection problems has been challenging for many years, especially with the appearance of the COVID-19 disease. Several studies have been proposed to solve the difficulties of this issue and to help practitioners to detect accurately the disease. These studies have used machine learning and deep learning approaches extensively.</p><sec id="s2_1"><title>2.1. Traditional Machine Learning Approaches</title><p>Santos and Melin [<xref ref-type="bibr" rid="scirp.132632-ref5">5</xref>] have considered the importance of the development of the computer-intelligence technique for pneumonia classification, they utilized the ML approach for diagnosis and detection where the segmentation technique is used for the extraction of the area of interest from the chest X-ray. The experimental results reveal a mean accuracy of 95%. Tuncer et al. [<xref ref-type="bibr" rid="scirp.132632-ref6">6</xref>] used a traditional machine learning-based system. The size of the dataset that has been used was small and imbalanced. It contains (135 for COVID-19, 150 for pneumonia, and 150 for normal radiographs), and they achieved an accuracy rate of 97.01%. For pneumonia X-ray classification, Sharma et al. [<xref ref-type="bibr" rid="scirp.132632-ref7">7</xref>] designed a simple CNN model, and to solve the problem of scarcity of data they utilized data augmentation. The achieved accuracy was around 90.68%.</p></sec><sec id="s2_2"><title>2.2. Deep Learning Approaches</title><p>Danilov et al. [<xref ref-type="bibr" rid="scirp.132632-ref8">8</xref>] have tested four deep learning networks to evaluate the performance for pneumonia, and COVID-19 classification, the networks are EffecientNet B1, B2, MobileNetV2, and VGG16 from 2631 CXRs. When they used fine-tuning, the presented model reached an accuracy of 78% which is not a promising value. To improve the model performance, the authors utilize Grad-CAM, which presents guided attention to the chest part based on the segmentation of U-Net. This technique improved the COVID-19, pneumonia classification. In [<xref ref-type="bibr" rid="scirp.132632-ref9">9</xref>] , the authors used deep learning instead of the reverse transcription polymerase chain reaction method for COVID-19 identification because it was found that the algorithm is time-consuming even though deep learning is showing promising performance. The dataset consists of 13,569 X-ray images split into healthy, non-COVID-19 pneumonia and COVID-19 patients. The results show that this approach presents an excellent model with an accuracy of 93.9%, a COVID-19 sensitivity of 96.8%, and a positive prediction of 100%. The authors in [<xref ref-type="bibr" rid="scirp.132632-ref10">10</xref>] have collected a dataset of X-ray images of healthy and COVID-19 patients, this dataset become the biggest dataset. Next, they trained a CNN model, and they achieved a total accuracy of 87.88%. Bhattacharyya et al. [<xref ref-type="bibr" rid="scirp.132632-ref11">11</xref>] presented a deep learning method combining image segmentation and classification models to detect COVID-19, and health efficiently. They used segmentation on X-ray raw images by the conditional generative adversarial network (C-GAN) with the algorithm called pix to pix. After that, they put segmented images into the network for feature extraction, which is a combination of several deep neural networks such as VGG-16, VGG19, and DensNet-160. In the end, they used different ML techniques to classify extracted features such as SoftMax, SVM, and XG boost. They obtained the highest accuracy with the VGG-19 model at 96.6%.</p></sec><sec id="s2_3"><title>2.3. Multi-Task Learning Approaches</title><p>Multi-task learning has proved its ability to work with classification and detection issues. Indeed, multi-tasking is a new pragmatism to solve these types of problems [<xref ref-type="bibr" rid="scirp.132632-ref12">12</xref>] . It can be used for different diseases using, for instance, chest X-ray images and CT scan images as input data. Indeed, in [<xref ref-type="bibr" rid="scirp.132632-ref13">13</xref>] , the authors have proposed an artificial neural network as a tool to detect lung diseases such as chronic obstructive pulmonary disease (COPD), pneumonia, and lung cancer. After a pre-processing of images to remove irrelevant data, statistical features are extracted like standard deviation, entropy, and mean. For the architecture, they used a feed-forward neural network to identify such diseases. The dataset is collected from Sasoon Hospital. In [<xref ref-type="bibr" rid="scirp.132632-ref14">14</xref>] , to diagnose CXR thoracic diseases, a new version of CNN was used, called Attention Guided convolutional neural network (AG-CNN), which is utilized to combine the global and local information to improve recognition performance. Authors in [<xref ref-type="bibr" rid="scirp.132632-ref15">15</xref>] have proposed an algorithm called chest-X-Net. This algorithm, with a CNN architecture, is composed of 121 layers. It takes an image of the chest as input and the result is the likelihood of thorax diseases. This approach (ChexNet) has been used successfully on 14 thoracic diseases. The authors in [<xref ref-type="bibr" rid="scirp.132632-ref16">16</xref>] have mentioned that the multi-task learning method utilizing deep neural networks was historically subdivided into two structures: soft parameter sharing and hard parameter sharing. In hard parameter sharing, the parameters set is typically divided into task-specific and shared parameters, whereas in soft parameter sharing each task has its own set of parameters, single head for each parameter set. Udeshani et al. [<xref ref-type="bibr" rid="scirp.132632-ref17">17</xref>] , proposed different approaches, where chest X-ray images are used to identify lung cancer. Using this approach, the achieved accuracy was 96% while using the feature-based technique the achieved accuracy was 88%. Al-Edhari et al. [<xref ref-type="bibr" rid="scirp.132632-ref18">18</xref>] used a deep learning algorithm by using X-ray images as input to identify the normal and abnormal classification of pneumonia disease. Liu et al. [<xref ref-type="bibr" rid="scirp.132632-ref19">19</xref>] used a defined multi-task architecture, which divided the feature space into a task space and a shared specific part. They mentioned that multi-task learning is a powerful technique able to enhance the performance of a single task with the aid of other tasks together [<xref ref-type="bibr" rid="scirp.132632-ref20">20</xref>] [<xref ref-type="bibr" rid="scirp.132632-ref21">21</xref>] . Hemdan et al. [<xref ref-type="bibr" rid="scirp.132632-ref22">22</xref>] developed many deep-learning approaches to classify CXR images for COVID-19 and non-COVID-19 patients. They introduce a novel approach namely COVIDX-Net to help doctors automatically detect the disease in CXR. They achieved good results with an accuracy of 90% by utilizing VGG16 and DenseNet201. In [<xref ref-type="bibr" rid="scirp.132632-ref23">23</xref>] , Yuxing Tang et al. presented a convolutional neural network based on attention-guided curriculum learning (AGCL) to increase the accuracy of localization and classification of thoracic diseases. In addition, they have exploited the use of a relevant attention-guided improvement framework to enhance the performance for both localization and classification. In [<xref ref-type="bibr" rid="scirp.132632-ref24">24</xref>] , the authors used deep convolutional neural networks to detect thoracic disease utilizing chest X-rays. This principle might have two drawbacks. Firstly, unmatched objects in all chest X-ray images may lead to unwanted noise. Secondly, it reduces the image resolution because of the scaled process. To solve both issues, the authors have proposed a new technique called a Segmentation-based Deep Fusion Network, which enhances field knowledge and high-resolution information for lung areas. Varshni et al. [<xref ref-type="bibr" rid="scirp.132632-ref25">25</xref>] proposed a deep learning model with a specific convolutional neural network for feature extraction with a transfer learning approach. Indeed, they provided a pneumonia identification system utilizing a Densely Connected Convolutional Neural Network’ (DenseNet-169). This model, composed of CNNs for feature extraction combined witha supervised classifier algorithm emerged as an optimal solution for detecting normal and abnormal X-ray chest images. Wesley et al. [<xref ref-type="bibr" rid="scirp.132632-ref26">26</xref>] utilized the Alexnet deep learning network with transfer learning. The dataset composed of 5659 images was utilized for training. It achieved 72% accuracy. In this paper transfer learning is used, CNN model is Alexnet. The last three layers of the Alexnet model were replaced by a fully connected layer. The rest of the layers are standard classification layers. The goal of the work presented in [<xref ref-type="bibr" rid="scirp.132632-ref2">2</xref>] is to use a multi-task deep learning methodology to identify patients with COVID-19. They employed their Inception Residual Recurrent Convolutional Neural Network with a transfer learning approach to detect COVID-19 disease using X-ray and CT scan images. The achieved accuracy for CT scan images was 98.78% and for X-ray images was around 84.67%. The authors in [<xref ref-type="bibr" rid="scirp.132632-ref27">27</xref>] described a new framework that relies on the encoder-decoder multi-task model. They have used the CXR real-world dataset which contains healthy, bacterial pneumonia, viral pneumonia, and COVID-19 pneumonia images. The average achieved accuracy was 87.9%. In [<xref ref-type="bibr" rid="scirp.132632-ref28">28</xref>] , the authors have proposed a multi-classification deep learning architecture to diagnose and classify four types of diseases including COVID-19, pneumonia, lung cancer, and normal cases. The dataset combines CT scans and CXR images. The results have shown that VGG19+CNN achieved the highest accuracy of 98.05%. Authors in [<xref ref-type="bibr" rid="scirp.132632-ref29">29</xref>] employed a multitask approach to consolidate both triage approaches and propose a deep convolutional neural network for identification and severity quantification of COVID-19 disease.</p></sec></sec><sec id="s3"><title>3. Materials and Methods</title><sec id="s3_1"><title>3.1. Dataset</title><p>In this study, two different datasets have been used. The first data set is chest X-ray radiographs [<xref ref-type="bibr" rid="scirp.132632-ref30">30</xref>] . It contains 5856 files labeled (pneumonia vs. normal), which are split into the testing set and training set. Testing set with (234 Normal and 390 Pneumonia) and training set with (1349 normal and 3883 pneumonia). These images are stored in the format of JPEG. The resizing operation has been performed on these images. Before the operation, they had a width of 1233 and a height of 1460. After resizing they become 224 &#215; 224 &#215; 3 to fit the models used, all models have the input image with size 224 &#215; 224 &#215; 3 except inceptionv3 which has an image size of 150 &#215; 150 &#215; 3. These operations make this dataset useful for our research. The second dataset contains CT scans for COVID-19 [<xref ref-type="bibr" rid="scirp.132632-ref30">30</xref>] , with a total number of 8.055 files split and labeled as (5427 COVID and 2628 Non-COVID). They are not split into training and testing sets, therefore, we manually split them into 20% for the testing set and 80% for the training set. <xref ref-type="fig" rid="fig1">Figure 1</xref> shows samples from both datasets.</p></sec><sec id="s3_2"><title>3.2. Proposed Models</title><p>Two different models of machine learning are proposed. Firstly, single-task deep</p><p>learning is used for the two disease classifications. Secondly, a multi-task deep</p><p>learning model for both diseases is developed. These two machine-learning models are evaluated on both CT scans for COVID-19 and X-ray images for pneumonia disease.</p><sec id="s3_2_1"><title>3.2.1. Single-Task Learning</title><p>For single-task learning, the input data is the image of the disease, and the goal is to predict a single outcome disease (see <xref ref-type="fig" rid="fig2">Figure 2</xref> for the pneumonia task).</p></sec><sec id="s3_2_2"><title>3.2.2. Multi-Task Learning Methods</title><p>Multi-task learning in general aims to learn multiple tasks together at the same time. This will improve the generalizability of the CNN models. MTL can be defined as the optimization of several losses in a single model such that shared representation learning can execute related tasks [<xref ref-type="bibr" rid="scirp.132632-ref4">4</xref>] . Multi-task learning in the context of advanced learning is often carried out using either soft or hard parameters sharing of the convolution layer.</p><p>1) Soft Parameter Sharing</p><p>In soft parameter sharing, every task has its model with different parameters. After calculation, the distance between parameters is regularized to make the parameters look similar. In this method, every task has a unique design with unique characteristics. The model’s parameters are then pushed to be close by regularizing the gap among them.</p><p>2) Hard Parameter Sharing</p><p>Hard sharing is a widespread MTL application used in machine learning. In this method, all tasks share hidden layer data, and the output layer of each task is different. The technique of MTL within neural network models that are most frequently employed goes back to [<xref ref-type="bibr" rid="scirp.132632-ref31">31</xref>] and is known as hard parameter sharing. Typically, this is implemented by preserving several layers that are task-specific layers while sharing the hidden features units across the training process. Overfitting is considerably diminished by hard parameter sharing. In reality, the authors in [<xref ref-type="bibr" rid="scirp.132632-ref32">32</xref>] demonstrated that the danger of overfitting overall shared parameters, or the hidden and output, is an order of N lower than the problem of overfitting the task-specific variables. The model structure used in this work is shown in <xref ref-type="fig" rid="fig3">Figure 3</xref>, where the model starts with shared layers, and after it splits into two specific layers.</p></sec></sec></sec><sec id="s4"><title>4. Results</title><p>The experiments are conducted using two different types of machine learning. Firstly, single-task deep learning is used for the two disease classifications. Secondly, a multi-task deep learning architecture is utilized for both diseases. These two machine learning types are evaluated on both CT scans for COVID-19 and X-ray images for pneumonia disease. The accuracy metric is used to compare different architectures for both STL and MTL (number of correct predictions)/(total number of predictions). It is noticed that the achieved accuracy of a single task is getting improved, using different models, and enhanced for multi-task learning approach.</p><sec id="s4_1"><title>4.1. Single-Task Learning</title><p>Four distinct state-of-the-art PCNN models, namely VGG-16, Inception-V3, Effi-cientNetB0, and ResNet-50, have been employed within the framework of a single-task model. These models were instantiated using Python’s machine-learning libraries and executed in the Google Colab environment. All these models have been retrained to find optimal weights that achieve better performances. The hyperparameters used for Re-seNet50 and EfficientNetB0 are shown in <xref ref-type="table" rid="table1">Table 1</xref>.</p><p>These networks were trained using 5 to 10 epochs, but to avoid overfitting, the training limit of 5 epochs will be used for multi-tasking. These models have a high performance with low overfitting. The batch size was chosen as 16 and to optimize the network parameter Adam optimizer was used with a learning rate of 0.0001. It decayed by 0.1 factor at the 5<sup>th</sup> epoch. In addition, the dataset used is a balanced dataset which means an equal number of images for each label. In this experiment, there were 500 images for each label of the COVID-19 and pneumonia dataset. <xref ref-type="table" rid="table2">Table 2</xref> and <xref ref-type="table" rid="table3">Table 3</xref> show different achieved accuracies for</p><table-wrap id="table1" ><label><xref ref-type="table" rid="table1">Table 1</xref></label><caption><title> Hyperparameters used for network structure (COVID-19) with ResNet50 and (Pneumonia) with effecientNetB0</title></caption><table><tbody><thead><tr><th align="center" valign="middle" >Number of Hidden Layers</th><th align="center" valign="middle" >179 layers for ResNet50 and 241 for EfficientNetB0</th></tr></thead><tr><td align="center" valign="middle" >Dropout</td><td align="center" valign="middle" >50%</td></tr><tr><td align="center" valign="middle" >Activation Function</td><td align="center" valign="middle" >ReLu</td></tr><tr><td align="center" valign="middle" >Learning Rate</td><td align="center" valign="middle" >0.0001</td></tr><tr><td align="center" valign="middle" >Number of Epochs</td><td align="center" valign="middle" >Tune from 5 to 10</td></tr><tr><td align="center" valign="middle" >Loss Function</td><td align="center" valign="middle" >Binary Cross Entropy</td></tr></tbody></table></table-wrap><table-wrap id="table2" ><label><xref ref-type="table" rid="table2">Table 2</xref></label><caption><title> Comparison of different pre-trained CNN for Pneumonia [<xref ref-type="bibr" rid="scirp.132632-ref43">43</xref>] </title></caption><table><tbody><thead><tr><th align="center" valign="middle" >Model</th><th align="center" valign="middle" ></th><th align="center" valign="middle" >Precision</th><th align="center" valign="middle" >Recall</th><th align="center" valign="middle" >F1 Score</th><th align="center" valign="middle" >Accuracy</th></tr></thead><tr><td align="center" valign="middle"  rowspan="2"  >VGG-16</td><td align="center" valign="middle" >Pneumonia</td><td align="center" valign="middle" >0.94</td><td align="center" valign="middle" >0.95</td><td align="center" valign="middle" >0.94</td><td align="center" valign="middle" >94.40%</td></tr><tr><td align="center" valign="middle" >Normal</td><td align="center" valign="middle" >0.95</td><td align="center" valign="middle" >0.94</td><td align="center" valign="middle" >0.94</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle"  rowspan="2"  >Inception-V3</td><td align="center" valign="middle" >Pneumonia</td><td align="center" valign="middle" >0.93</td><td align="center" valign="middle" >0.84</td><td align="center" valign="middle" >0.88</td><td align="center" valign="middle" >87.50%</td></tr><tr><td align="center" valign="middle" >Normal</td><td align="center" valign="middle" >0.82</td><td align="center" valign="middle" >0.92</td><td align="center" valign="middle" >0.87</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle"  rowspan="2"  >EffecientNetB0</td><td align="center" valign="middle" >Pneumonia</td><td align="center" valign="middle" >0.97</td><td align="center" valign="middle" >0.96</td><td align="center" valign="middle" >0.97</td><td align="center" valign="middle" >96.50%</td></tr><tr><td align="center" valign="middle" >Normal</td><td align="center" valign="middle" >0.96</td><td align="center" valign="middle" >0.97</td><td align="center" valign="middle" >0.96</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle"  rowspan="2"  >ResNet-50</td><td align="center" valign="middle" >Pneumonia</td><td align="center" valign="middle" >0.99</td><td align="center" valign="middle" >0.89</td><td align="center" valign="middle" >0.94</td><td align="center" valign="middle" >93.20%</td></tr><tr><td align="center" valign="middle" >Normal</td><td align="center" valign="middle" >0.87</td><td align="center" valign="middle" >0.99</td><td align="center" valign="middle" >0.92</td><td align="center" valign="middle" ></td></tr></tbody></table></table-wrap><table-wrap id="table3" ><label><xref ref-type="table" rid="table3">Table 3</xref></label><caption><title> Comparison of different pre-trained CNN for COVID-19 [<xref ref-type="bibr" rid="scirp.132632-ref43">43</xref>] </title></caption><table><tbody><thead><tr><th align="center" valign="middle" >Model</th><th align="center" valign="middle" ></th><th align="center" valign="middle" >Precision</th><th align="center" valign="middle" >Recall</th><th align="center" valign="middle" >F1 Score</th><th align="center" valign="middle" >Accuracy</th></tr></thead><tr><td align="center" valign="middle"  rowspan="2"  >VGG-16</td><td align="center" valign="middle" >Non-COVID</td><td align="center" valign="middle" >0.99</td><td align="center" valign="middle" >0.99</td><td align="center" valign="middle" >0.99</td><td align="center" valign="middle"  rowspan="2"  >99%</td></tr><tr><td align="center" valign="middle" >COVID</td><td align="center" valign="middle" >0.99</td><td align="center" valign="middle" >0.99</td><td align="center" valign="middle" >0.99</td></tr><tr><td align="center" valign="middle"  rowspan="2"  >Inception-V3</td><td align="center" valign="middle" >Non-COVID</td><td align="center" valign="middle" >0.89</td><td align="center" valign="middle" >1.00</td><td align="center" valign="middle" >0.94</td><td align="center" valign="middle"  rowspan="2"  >95%</td></tr><tr><td align="center" valign="middle" >COVID</td><td align="center" valign="middle" >1.00</td><td align="center" valign="middle" >0.91</td><td align="center" valign="middle" >0.95</td></tr><tr><td align="center" valign="middle"  rowspan="2"  >EffecientNetB0</td><td align="center" valign="middle" >Non-COVID</td><td align="center" valign="middle" >0.99</td><td align="center" valign="middle" >0.96</td><td align="center" valign="middle" >0.97</td><td align="center" valign="middle"  rowspan="2"  >97.5%</td></tr><tr><td align="center" valign="middle" >COVID</td><td align="center" valign="middle" >0.96</td><td align="center" valign="middle" >0.99</td><td align="center" valign="middle" >0.97</td></tr><tr><td align="center" valign="middle"  rowspan="2"  >ResNet-50</td><td align="center" valign="middle" >Non-COVID</td><td align="center" valign="middle" >0.99</td><td align="center" valign="middle" >1.00</td><td align="center" valign="middle" >0.99</td><td align="center" valign="middle"  rowspan="2"  >99.5%</td></tr><tr><td align="center" valign="middle" >COVID</td><td align="center" valign="middle" >1.00</td><td align="center" valign="middle" >0.99</td><td align="center" valign="middle" >0.99</td></tr></tbody></table></table-wrap><p>single-task learning. For the Pneumonia disease, the highest score is realized by the EffecientNetB0 model (96.50%). Whereas for the COVID-19 disease, the ResNet-50 model reached the highest accuracy at 99.5%. Therefore, to conclude this part, the highest accuracy performance for single-task learning was obtained with the architecture ResNet-50 up to 99.5%, and it will be used as PCNN in the MTL. <xref ref-type="fig" rid="fig4">Figure 4</xref> illustrates a sample of accuracy during the training and validation phase with the loss function variation.</p></sec><sec id="s4_2"><title>4.2. Multi-Task Learning</title><p>The model of a single-task has been enhanced by building multi-task frameworks. Single-task performance will be improved by using multi-task deep learning with its two main methods which are hard parameter sharing and soft parameter sharing. The most useful is hard parameter sharing, here it achieved an accuracy of 99.9%. However, with soft parameter sharing the performance was not promising. The same hyperparameters used in single-task learning have been followed with some slight differences. For instance, Adam optimizer was used, the batch size was 64, the learning rate with 0.001, and the number of epochs varied from 5 to 10. These parameters have been adjusted until the desired accuracy is achieved. <xref ref-type="fig" rid="fig5">Figure 5</xref> and <xref ref-type="fig" rid="fig6">Figure 6</xref> depict the training and validation accuracies with their corresponding loss functions.</p></sec><sec id="s4_3"><title>4.3. Models Performance and Discussion</title><p>In this work, we performed and compared the performances of different models. First, we compare the accuracy of pre-trained architectures (PCNNs) to determine the best one. It has been found that ResNet-50 outperforms the other PCNN models. This model has been chosen to be used in the multi-task approach for even more enhancement. <xref ref-type="table" rid="table4">Table 4</xref> shows different achieved accuracies for COVID-19 and Pneumonia diseases. Further, the total number of parameters for each model is also mentioned. The second table (<xref ref-type="table" rid="table5">Table 5</xref>) is related to the achieved performance of multi-task learning using the RESNET-50 model,</p><table-wrap id="table4" ><label><xref ref-type="table" rid="table4">Table 4</xref></label><caption><title> The accuracy was achieved with different PCNNs for CT scan and CXR2</title></caption><table><tbody><thead><tr><th align="center" valign="middle" >Model</th><th align="center" valign="middle"  colspan="2"  >Accuracy</th><th align="center" valign="middle" >Number of Parameters</th></tr></thead><tr><td align="center" valign="middle"  rowspan="2"  >VGG-16</td><td align="center" valign="middle" >COVID-19</td><td align="center" valign="middle" >99%</td><td align="center" valign="middle"  rowspan="2"  >27,560,769</td></tr><tr><td align="center" valign="middle" >Pneumonia</td><td align="center" valign="middle" >94.40%</td></tr><tr><td align="center" valign="middle"  rowspan="2"  >Inception-V3</td><td align="center" valign="middle" >COVID-19</td><td align="center" valign="middle" >95%</td><td align="center" valign="middle"  rowspan="2"  >31,240,993</td></tr><tr><td align="center" valign="middle" >Pneumonia</td><td align="center" valign="middle" >87.50%</td></tr><tr><td align="center" valign="middle"  rowspan="2"  >EficientNetB0</td><td align="center" valign="middle" >COVID-19</td><td align="center" valign="middle" >97.5%</td><td align="center" valign="middle"  rowspan="2"  >36,163,236</td></tr><tr><td align="center" valign="middle" >Pneumonia</td><td align="center" valign="middle" >96.50%</td></tr><tr><td align="center" valign="middle"  rowspan="2"  >ResNet-50</td><td align="center" valign="middle" >COVID-19</td><td align="center" valign="middle" >99.5%</td><td align="center" valign="middle"  rowspan="2"  >74,968,961</td></tr><tr><td align="center" valign="middle" >Pneumonia</td><td align="center" valign="middle" >93.20</td></tr></tbody></table></table-wrap><table-wrap id="table5" ><label><xref ref-type="table" rid="table5">Table 5</xref></label><caption><title> MTL methods with the ResNet-50 model and their achieved accuracy</title></caption><table><tbody><thead><tr><th align="center" valign="middle" >Multi-Task Learning Method</th><th align="center" valign="middle" >PCNN Model</th><th align="center" valign="middle" >Accuracy</th></tr></thead><tr><td align="center" valign="middle" >Soft Sharing Parameters</td><td align="center" valign="middle" >ResNet-50</td><td align="center" valign="middle" >93.8%</td></tr><tr><td align="center" valign="middle" >Hard Sharing Parameters</td><td align="center" valign="middle" >ResNet-50</td><td align="center" valign="middle" >99.9%</td></tr></tbody></table></table-wrap><p>where it is noticed that it has achieved the best accuracy under a hard parameter sharing structure, in comparison with the soft parameter sharing structure (see <xref ref-type="table" rid="table4">Table 4</xref> and <xref ref-type="table" rid="table5">Table 5</xref>).</p><p>Moreover, comparisons of this work with others who have almost the same dataset with the same architectures are conducted. The models and the achieved accuracies are shown in <xref ref-type="table" rid="table6">Table 6</xref> for single-task learning and <xref ref-type="table" rid="table7">Table 7</xref> for multi-task learning approaches. Further, in this table, a comparison of the proposed scheme with their results is also displayed. The proposed models have outperformed their accuracies in both approaches single-task learning and multi-task learning as well. Therefore, we consider that we overcome their limitations and improve the accuracy of the classification. (See the comparison <xref ref-type="table" rid="table6">Table 6</xref>).</p><p>Furthermore, the achieved accuracies (see <xref ref-type="table" rid="table5">Table 5</xref>) are promising with a multi-task deep learning framework under the method of hard parameter sharing. The achieved accuracy is 99.9%, whereas with the second method, using soft parameter sharing, the performance achieved was up to 93.8% with the ResNet-50 model. In addition, the same work has been tested with EfficeintNetB0 since it achieves high accuracy in single-task learning for pneumonia disease, but it performs poor performance, and for this reason, this model has been ignored. We have used only the architecture of ResNet-50 since it achieved the highest result among the other architectures in single-task learning. We further improve this architecture using multi-task learning.</p><p><xref ref-type="fig" rid="fig7">Figure 7</xref> shows several prediction scores of the proposed method. The trained model clearly distinguishes Pneumonia, COVID-19 diseases, and normal.</p><table-wrap id="table6" ><label><xref ref-type="table" rid="table6">Table 6</xref></label><caption><title> Comparison with recent models using single-task learning with CT scan and CXR</title></caption><table><tbody><thead><tr><th align="center" valign="middle" >Research</th><th align="center" valign="middle" >Date</th><th align="center" valign="middle" >VGG-16</th><th align="center" valign="middle" >EffecientNet-B0</th><th align="center" valign="middle" >Inception-V3</th><th align="center" valign="middle" >Resnet-50</th></tr></thead><tr><td align="center" valign="middle" >[<xref ref-type="bibr" rid="scirp.132632-ref33">33</xref>]</td><td align="center" valign="middle" >2020</td><td align="center" valign="middle" >87.18%</td><td align="center" valign="middle" >-</td><td align="center" valign="middle" >70.99%</td><td align="center" valign="middle" >77.56%</td></tr><tr><td align="center" valign="middle" >[<xref ref-type="bibr" rid="scirp.132632-ref34">34</xref>]</td><td align="center" valign="middle" >2021</td><td align="center" valign="middle" >82.30%</td><td align="center" valign="middle" >-</td><td align="center" valign="middle" >-</td><td align="center" valign="middle" >86.73%</td></tr><tr><td align="center" valign="middle" >[<xref ref-type="bibr" rid="scirp.132632-ref35">35</xref>]</td><td align="center" valign="middle" >2021</td><td align="center" valign="middle" >-</td><td align="center" valign="middle" >96.33%</td><td align="center" valign="middle" >-</td><td align="center" valign="middle" >-</td></tr><tr><td align="center" valign="middle" >[<xref ref-type="bibr" rid="scirp.132632-ref36">36</xref>]</td><td align="center" valign="middle" >2021</td><td align="center" valign="middle" >89.90%</td><td align="center" valign="middle" >93%</td><td align="center" valign="middle" >-</td><td align="center" valign="middle" >89.90%</td></tr><tr><td align="center" valign="middle" >[<xref ref-type="bibr" rid="scirp.132632-ref37">37</xref>]</td><td align="center" valign="middle" >2020</td><td align="center" valign="middle" >-</td><td align="center" valign="middle" >94.62%</td><td align="center" valign="middle" >-</td><td align="center" valign="middle" >-</td></tr><tr><td align="center" valign="middle" >[<xref ref-type="bibr" rid="scirp.132632-ref38">38</xref>]</td><td align="center" valign="middle" >2021</td><td align="center" valign="middle" >-</td><td align="center" valign="middle" >89.3%</td><td align="center" valign="middle" >82.9%</td><td align="center" valign="middle" >78%</td></tr><tr><td align="center" valign="middle" >[<xref ref-type="bibr" rid="scirp.132632-ref39">39</xref>]</td><td align="center" valign="middle" >2020</td><td align="center" valign="middle" >87.12%</td><td align="center" valign="middle" >-</td><td align="center" valign="middle" >89.38%</td><td align="center" valign="middle" >96.97%</td></tr><tr><td align="center" valign="middle" >[<xref ref-type="bibr" rid="scirp.132632-ref40">40</xref>]</td><td align="center" valign="middle" >2021</td><td align="center" valign="middle" >-</td><td align="center" valign="middle" >95%</td><td align="center" valign="middle" >-</td><td align="center" valign="middle" >90.6%</td></tr><tr><td align="center" valign="middle" >[<xref ref-type="bibr" rid="scirp.132632-ref41">41</xref>]</td><td align="center" valign="middle" >2020</td><td align="center" valign="middle" >83.68%</td><td align="center" valign="middle" >78.40%</td><td align="center" valign="middle" ></td><td align="center" valign="middle" >77.76%</td></tr><tr><td align="center" valign="middle" >[<xref ref-type="bibr" rid="scirp.132632-ref42">42</xref>]</td><td align="center" valign="middle" >2021</td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >OURS (CT SCAN)</td><td align="center" valign="middle" >2022</td><td align="center" valign="middle" >99%</td><td align="center" valign="middle" >97.5%</td><td align="center" valign="middle" >95%</td><td align="center" valign="middle" >99.5%</td></tr><tr><td align="center" valign="middle" >OURS(CXR)</td><td align="center" valign="middle" >2022</td><td align="center" valign="middle" >94.40%</td><td align="center" valign="middle" >96.50%</td><td align="center" valign="middle" >87.50%</td><td align="center" valign="middle" >93.20%</td></tr></tbody></table></table-wrap><table-wrap id="table7" ><label><xref ref-type="table" rid="table7">Table 7</xref></label><caption><title> Comparison with other models using the multi-task learning method</title></caption><table><tbody><thead><tr><th align="center" valign="middle" >Research</th><th align="center" valign="middle" >Date</th><th align="center" valign="middle" >Approach</th><th align="center" valign="middle" >Accuracy</th></tr></thead><tr><td align="center" valign="middle" >[<xref ref-type="bibr" rid="scirp.132632-ref2">2</xref>]</td><td align="center" valign="middle" >2020</td><td align="center" valign="middle" >Multitask Learning</td><td align="center" valign="middle" >98.78%</td></tr><tr><td align="center" valign="middle" >[<xref ref-type="bibr" rid="scirp.132632-ref27">27</xref>]</td><td align="center" valign="middle" >2021</td><td align="center" valign="middle" >Encoder-decoder-encoder Multitask Model</td><td align="center" valign="middle" >87.9%</td></tr><tr><td align="center" valign="middle" >[<xref ref-type="bibr" rid="scirp.132632-ref28">28</xref>]</td><td align="center" valign="middle" >2021</td><td align="center" valign="middle" >Multi-Classification DL Model</td><td align="center" valign="middle" >98.05%</td></tr><tr><td align="center" valign="middle" >[<xref ref-type="bibr" rid="scirp.132632-ref1">1</xref>]</td><td align="center" valign="middle" >2019</td><td align="center" valign="middle" >Multi-Classification Approach</td><td align="center" valign="middle" >88.3%</td></tr><tr><td align="center" valign="middle" >[<xref ref-type="bibr" rid="scirp.132632-ref45">45</xref>]</td><td align="center" valign="middle" >2022</td><td align="center" valign="middle" >MTL against Radiology</td><td align="center" valign="middle" >90.3%</td></tr><tr><td align="center" valign="middle" >OURS (CXR)</td><td align="center" valign="middle" >2022</td><td align="center" valign="middle" >Multitask Learning (Hard sharing Parameters)</td><td align="center" valign="middle" >99.9%</td></tr></tbody></table></table-wrap></sec></sec><sec id="s5"><title>5. Conclusion</title><p>In this work, two main deep learning architectures have been performed which are related to the deep learning paradigm. Two different real-world datasets for training and testing have been used, and two different learning models have been utilized (single-task learning and multi-task learning). A single-task model is trained with several state-of-the-art architectures. For the multi-task learning approach, the architecture that achieved the best performance among other PCNNs, is used in MTL. It is found that ResNet-50 has achieved the best accuracy. All the models have been evaluated on two types of medical images, which are CT scans for COVID-19 and CXR for pneumonia. Further, in addition to the multi-task approach, many types of machine learning architectures have been trained and tested for performance inquiry. A comparison between the achieved results with the recent works is conducted. It is noticed that the proposed model under a multi-task structure with hard parameter sharing outperformed their accuracies. Indeed, the performances have been improved by fine-tuning hyperparameters, pre-processing images, and using a balanced dataset. Finally, using this kind of proposed deep learning model may help physicians to early detection of such chest diseases, which will protect human life and health.</p></sec><sec id="s6"><title>Conflicts of Interest</title><p>The authors declare no conflicts of interest regarding the publication of this paper.</p></sec><sec id="s7"><title>Cite this paper</title><p>Al Zahrani, N., Hedjar, R., Mekhtiche, M., Bencherif, M., Al Fakih, T., Al-Qershi, F. and Alrazghan, M. (2024) A Multi-Task Deep Learning Framework for Simultaneous Detection of Thoracic Pathology through Image Classification. Journal of Computer and Communications, 12, 153-170. https://doi.org/10.4236/jcc.2024.124012</p></sec></body><back><ref-list><title>References</title><ref id="scirp.132632-ref1"><label>1</label><mixed-citation publication-type="other" xlink:type="simple">Guendel, S., Ghesu, F.C., Grbic, S., Gibson, E., Georgescu, B., Maier, A. and Comaniciu, D. (2019) Multi-Task Learning for Chest X-Ray Abnormality Classification on Noisy Labels.</mixed-citation></ref><ref id="scirp.132632-ref2"><label>2</label><mixed-citation publication-type="other" xlink:type="simple">Alom, M.Z., Rahman, M., Nasrin, M.S., Taha, T.M. and Asari, V.K. (2020) COVID_ MTNet: COVID-19 Detection with Multi-Task Deep Learning Approaches. &lt;br&gt;https://arxiv.org/abs/2004.03747 </mixed-citation></ref><ref id="scirp.132632-ref3"><label>3</label><mixed-citation publication-type="other" xlink:type="simple">Farag, A.T., Abd El-Wahab, A.R., Nada, M., Abd El-Hakeem, M.Y., Mahmoud, O.S., Rashwan, R.K. and El Sallab, A. (2020) MultiCheXNet: A Multi-Task Learning Deep Network for Pneumonia-Like Diseases Diagnosis from X-Ray Scans. &lt;br&gt;https://arxiv.org/abs/2008.01973 </mixed-citation></ref><ref id="scirp.132632-ref4"><label>4</label><mixed-citation publication-type="other" xlink:type="simple">Haque, P., Wang, A. and Terzopoulos, D. (2021) Multimix: Sparingly-Supervised, Extreme Multitask Learning from Medical Images. &lt;i&gt;IEEE &lt;/i&gt;18&lt;i&gt;th&lt;/i&gt;&lt;i&gt; International Symp&lt;/i&gt;&lt;i&gt;o&lt;/i&gt;&lt;i&gt;sium on Biomedical Imaging &lt;/i&gt;(&lt;i&gt;ISBI&lt;/i&gt;), Nice, 13-16 April 2021, 693-696. &lt;br&gt;https://doi.org/10.1109/ISBI48211.2021.9434167</mixed-citation></ref><ref id="scirp.132632-ref5"><label>5</label><mixed-citation publication-type="book" xlink:type="simple">Varela-Santos, S. and Melin, P. (2020) Classification of X-Ray Images for Pneumonia Detection Using Texture Features and Neural Networks. In: Castillo, O., Melin, P. and Kacprzyk, J., Eds., &lt;i&gt;Intuitionistic Type&lt;/i&gt;-2&lt;i&gt; Fuzzy Logic Enhancements in Neu&lt;/i&gt;&lt;i&gt;r&lt;/i&gt;&lt;i&gt;al Optimization Algorithms&lt;/i&gt;:&lt;i&gt; Theory Applications&lt;/i&gt;, Springer, Berlin, 237-253. &lt;br&gt;https://doi.org/10.1007/978-3-030-35445-9_20</mixed-citation></ref><ref id="scirp.132632-ref6"><label>6</label><mixed-citation publication-type="other" xlink:type="simple">Tuncer, T., Ozyurt, F., Dogan, S. and Subasi, A. (2021) A Novel COVID-19 and Pneumonia Classification Method Based on F-Transform. &lt;i&gt;Chemometrics Intelligent Laboratory Systems&lt;/i&gt;, 210, Article ID: 104256. &lt;br&gt;https://doi.org/10.1016/j.chemolab.2021.104256</mixed-citation></ref><ref id="scirp.132632-ref7"><label>7</label><mixed-citation publication-type="other" xlink:type="simple">Sharma, H., Jain, J.S., Bansal, P. and Gupta, S. (2020) Feature Extraction and Classification of Chest X-Ray Images Using CNN to Detect Pneumonia. 10&lt;i&gt;th&lt;/i&gt;&lt;i&gt; Internatio&lt;/i&gt;&lt;i&gt;n&lt;/i&gt;&lt;i&gt;al &lt;/i&gt;&lt;i&gt;Conference on Cloud Computing&lt;/i&gt;,&lt;i&gt; Data Science &amp; Engineering&lt;/i&gt;, Noida, 29-31 January 2020, 227-231. &lt;br&gt;https://doi.org/10.1109/Confluence47617.2020.9057809</mixed-citation></ref><ref id="scirp.132632-ref8"><label>8</label><mixed-citation publication-type="other" xlink:type="simple">Danilov, V., &lt;i&gt;et al&lt;/i&gt;. (2021) COVID-19/Pneumonia Classification Based on Guided Attention. &lt;br&gt;https://doi.org/10.21203/rs.3.rs-149472/v1</mixed-citation></ref><ref id="scirp.132632-ref9"><label>9</label><mixed-citation publication-type="other" xlink:type="simple">Luz, V., &lt;i&gt;et al&lt;/i&gt;. (2021) Towards an Effective and Efficient Deep Learning Model for COVID-19 Patterns Detection in X-Ray Images. &lt;i&gt;Research on Biomedical Enginee&lt;/i&gt;&lt;i&gt;r&lt;/i&gt;&lt;i&gt;ing&lt;/i&gt;, 38, 149-162. &lt;br&gt;https://doi.org/10.1007/s42600-021-00151-6</mixed-citation></ref><ref id="scirp.132632-ref10"><label>10</label><mixed-citation publication-type="other" xlink:type="simple">Haghanifar, A., Majdabadi, M.M., Choi, Y., Deivalakshmi, S. and Ko, S. (2022) Covid-Cxnet: Detecting COVID-19 in Frontal Chest X-Ray Images Using Deep Learning&lt;i&gt;.&lt;/i&gt;&lt;i&gt; Multimedia Tools Applications&lt;/i&gt;, 81, 30615-30645. &lt;br&gt;https://doi.org/10.1007/s11042-022-12156-z</mixed-citation></ref><ref id="scirp.132632-ref11"><label>11</label><mixed-citation publication-type="other" xlink:type="simple">Bhattacharyya, A., Bhaik, D., Kumar, S., Thakur, P., Sharma, R. and Pachori, R.B. (2022) A Deep Learning-Based Approach for Automatic Detection of COVID-19 Cases Using Chest X-Ray Images&lt;i&gt;.&lt;/i&gt;&lt;i&gt; &lt;/i&gt;&lt;i&gt;Biomedical Signal Processing and Control&lt;/i&gt;, 71, Article ID: 103182. &lt;br&gt;https://doi.org/10.1016/j.bspc.2021.103182</mixed-citation></ref><ref id="scirp.132632-ref12"><label>12</label><mixed-citation publication-type="other" xlink:type="simple">Crawshaw, M. (2020) Multi-Task Learning with Deep Neural Networks: A Survey. &lt;br&gt;https://arxiv.org/abs/2009.09796 </mixed-citation></ref><ref id="scirp.132632-ref13"><label>13</label><mixed-citation publication-type="other" xlink:type="simple">Khobragade, S., Tiwari, A., Patil, C. and Narke, V. (2016) Automatic Detection of Major Lung Diseases Using Chest Radiographs and Classification by the Feed-Forward Artificial Neural Network. &lt;i&gt;IEEE &lt;/i&gt;1&lt;i&gt;st&lt;/i&gt;&lt;i&gt; &lt;/i&gt;&lt;i&gt;International&lt;/i&gt;&lt;i&gt; &lt;/i&gt;&lt;i&gt;Conference on Power Electronics&lt;/i&gt;,&lt;i&gt; Intelligent Control and Energy Systems&lt;/i&gt; (&lt;i&gt;ICPEICES&lt;/i&gt;), Delhi, 4-6 July 2016, 1-5. &lt;br&gt;https://doi.org/10.1109/ICPEICES.2016.7853683</mixed-citation></ref><ref id="scirp.132632-ref14"><label>14</label><mixed-citation publication-type="other" xlink:type="simple">Guan, Q., Huang, Y., Zhong, Z., Zheng, Z., Zheng, L. and Yang, Y. (2018) Diagnose Like a Radiologist: Attention Guided Convolutional Neural Network for Thorax Disease Classification. &lt;br&gt;https://arxiv.org/abs/1801.09927 </mixed-citation></ref><ref id="scirp.132632-ref15"><label>15</label><mixed-citation publication-type="other" xlink:type="simple">Rajpurkar, P., Irvin, J., Zhu, K., Yang, B., Mehta, H., Duan, T., Ding, D., Bagul, A., Langlotz, C., Shpanskaya, K., Lungren, M.P. and Andrew, Y.N. (2017) Chexnet: Radiologist-Level Pneumonia Detection on Chest X-Rays with Deep Learning. &lt;br&gt;https://arxiv.org/abs/1711.05225 </mixed-citation></ref><ref id="scirp.132632-ref16"><label>16</label><mixed-citation publication-type="other" xlink:type="simple">Vandenhende, S., Georgoulis, S., Gansbeke, W.V., Proesmans, M., Dai, D. and Gool, L.V. (2021) Multi-Task Learning for Dense Prediction Tasks: A Survey. &lt;i&gt;Compu&lt;/i&gt;&lt;i&gt;ter V&lt;/i&gt;&lt;i&gt;i&lt;/i&gt;&lt;i&gt;sion and Pattern Recognition&lt;/i&gt;, 44, 3614-3633. &lt;br&gt;https://doi.org/10.1109/TPAMI.2021.3054719</mixed-citation></ref><ref id="scirp.132632-ref17"><label>17</label><mixed-citation publication-type="other" xlink:type="simple">Udeshani, K.A.G., Meegama, G. and Fernando, T.G.I. (2011) Statistical Feature-Based Neural Network Approach for the Detection of Lung Cancer in Chest X-Ray Images. &lt;i&gt;International Journal of Image Processing&lt;/i&gt;, 5, 425-434.</mixed-citation></ref><ref id="scirp.132632-ref18"><label>18</label><mixed-citation publication-type="other" xlink:type="simple">Aledhari, M., Joji, S., Hefeida, M. and Saeed, F. (2019) Optimized CNN-Based Diagnosis System to Detect Pneumonia from Chest Radiographs. &lt;i&gt;IEEE International Conference on Bioinformatics and Biomedicine&lt;/i&gt; (&lt;i&gt;BIBM&lt;/i&gt;), San Diego, 18-21 November 2019, 2405-2412. &lt;br&gt;https://doi.org/10.1109/BIBM47256.2019.8983114</mixed-citation></ref><ref id="scirp.132632-ref19"><label>19</label><mixed-citation publication-type="other" xlink:type="simple">Liu, P., Qiu, X. and Huang, X. (2017) Adversarial Multi-Task Learning for Text Classification. &lt;i&gt;Proceedings of the &lt;/i&gt;55&lt;i&gt;th Annual Meeting of the Association for Co&lt;/i&gt;&lt;i&gt;m&lt;/i&gt;&lt;i&gt;put&lt;/i&gt;&lt;i&gt;ational Linguistics&lt;/i&gt;, Vancouver, 30 July-4 August 2017, 1-10. &lt;br&gt;https://doi.org/10.18653/v1/P17-1001</mixed-citation></ref><ref id="scirp.132632-ref20"><label>20</label><mixed-citation publication-type="other" xlink:type="simple">Maninis, K.K., Radosavovic, I. and Kokkinos, I. (2019) Attentive Single-Tasking of Multiple Tasks. &lt;i&gt;Proceedings of the IEEE&lt;/i&gt;/&lt;i&gt;CVF Conference on Computer Vision and Pattern Recognition&lt;/i&gt;, Long Beach, 15-20 June 2019, 1851-1860. &lt;br&gt;https://doi.org/10.1109/CVPR.2019.00195</mixed-citation></ref><ref id="scirp.132632-ref21"><label>21</label><mixed-citation publication-type="other" xlink:type="simple">Sinha, A., Chen, Z., Badrinarayanan, V. and Rabinovich, A.J. (2018) Gradient Adversarial Training of Neural Networks. &lt;br&gt;https://arxiv.org/abs/1806.08028 </mixed-citation></ref><ref id="scirp.132632-ref22"><label>22</label><mixed-citation publication-type="other" xlink:type="simple">Hemdan, E.E.-D., Shouman, M.A. and Karar, M.E. (2020) Covidx-Net: A Framework of Deep Learning Classifiers to Diagnose COVID-19 in X-Ray Images.&lt;br&gt;https://arxiv.org/abs/2003.11055 </mixed-citation></ref><ref id="scirp.132632-ref23"><label>23</label><mixed-citation publication-type="book" xlink:type="simple">Tang, Y., Wang, X., Harrison, A.P., Lu, L., Xiao, J. and Summers, R.M. (2018) Attention-Guided Curriculum Learning for Weakly Supervised Classification and Localization of Thoracic Diseases on Chest Radiographs. In: Shi, Y., Suk, H.I. and Liu, M., Eds., &lt;i&gt;Machine Learning in Medical Imaging&lt;/i&gt;. &lt;i&gt;MLMI&lt;/i&gt; 2018. &lt;i&gt;Lecture Notes in Computer Science&lt;/i&gt;, Springer, Cham. &lt;br&gt;https://doi.org/10.1007/978-3-030-00919-9_29</mixed-citation></ref><ref id="scirp.132632-ref24"><label>24</label><mixed-citation publication-type="other" xlink:type="simple">Liu, H., &lt;i&gt;et al&lt;/i&gt;. (2019) SDFN: Segmentation-Based Deep Fusion Network for Thoracic Disease Classification in Chest X-Ray Images&lt;i&gt;. Computerized Medical Imaging and Graphics&lt;/i&gt;, 75, 66-73. &lt;br&gt;https://doi.org/10.1016/j.compmedimag.2019.05.005</mixed-citation></ref><ref id="scirp.132632-ref25"><label>25</label><mixed-citation publication-type="other" xlink:type="simple">Varshni, D., Thakral, K., Agarwal, L., Nijhawan, R. and Mittal, A. (2019) Pneumonia Detection Using CNN-Based Feature Extraction. &lt;i&gt;IEEE International Conference on Electrical&lt;/i&gt;,&lt;i&gt; Computer and Communication Technologies&lt;/i&gt; (&lt;i&gt;ICECCT&lt;/i&gt;), Coimbatore, 20-22 February 2019, 1-7. &lt;br&gt;https://doi.org/10.1109/ICECCT.2019.8869364</mixed-citation></ref><ref id="scirp.132632-ref26"><label>26</label><mixed-citation publication-type="other" xlink:type="simple">Wesley, O., Haddad, R.J. and Moore, D.L. (2019) Pneumonia Radiograph Diagnosis Utilizing Deep Learning Network. 2&lt;i&gt;nd&lt;/i&gt;&lt;i&gt; International Conference on Electronic I&lt;/i&gt;&lt;i&gt;n&lt;/i&gt;&lt;i&gt;formation and Communication Technology &lt;/i&gt;(&lt;i&gt;ICEICT&lt;/i&gt;), Harbin, 20-22 January 2019, 763-767.</mixed-citation></ref><ref id="scirp.132632-ref27"><label>27</label><mixed-citation publication-type="other" xlink:type="simple">Zhang, X., Han, L., Sobeih, T., Han, L., Dempsey, N., Lechareas, S., Tridente, A., Chen, H. and White, S. (2021) CXR-Net: An Encoder-Decoder-Encoder Multitask Deep Neural Network for Explainable and Accurate Diagnosis of COVID-19 Pneumonia with Chest X-Ray Images. &lt;br&gt;https://arxiv.org/abs/2110.10813 </mixed-citation></ref><ref id="scirp.132632-ref28"><label>28</label><mixed-citation publication-type="other" xlink:type="simple">Ibrahim, D.M., Elshennawy, N.M. and Sarhan, A.M. (2021) Deep-Chest: Multi-Classification Deep Learning Model for Diagnosing COVID-19, Pneumonia, and Lung Cancer Chest Diseases. &lt;i&gt;Computers in Biology and Medicine&lt;/i&gt;, 132, Article ID: 104348. &lt;br&gt;https://doi.org/10.1016/j.compbiomed.2021.104348</mixed-citation></ref><ref id="scirp.132632-ref29"><label>29</label><mixed-citation publication-type="other" xlink:type="simple">Goncharov, M., Pisov, M., Shevtsov, A., Shirokikh, B., Kurmukov, A., Blokhinc, I., Cherninac, V., Solovev, A. Gombolevskiy, V., Morozov, S. and Belyaev, M. (2021) CT-Based COVID-19 Triage: Deep Multitask Learning Improves Joint Identification and Severity Quantification. &lt;i&gt;Medical Image Analysis&lt;/i&gt;,&lt;i&gt; &lt;/i&gt;71, Article ID: 102054. &lt;br&gt;https://doi.org/10.1016/j.media.2021.102054</mixed-citation></ref><ref id="scirp.132632-ref30"><label>30</label><mixed-citation publication-type="other" xlink:type="simple">Mooney, P. (2018) Kaggle Chest X-Ray Images (Pneumonia) Dataset. &lt;br&gt;https://www.kaggle.com/datasets/paultimothymooney/chest-xray-pneumonia </mixed-citation></ref><ref id="scirp.132632-ref31"><label>31</label><mixed-citation publication-type="other" xlink:type="simple">Guo, P., Lee, C.Y. and Ulbricht, D. (2020) Learning to Branch for Multi-Task Learning. &lt;i&gt;Proceedings of the &lt;/i&gt;37&lt;i&gt;th&lt;/i&gt;&lt;i&gt; International C&lt;/i&gt;&lt;i&gt;onference on &lt;/i&gt;&lt;i&gt;Machine Learning&lt;/i&gt;, 13-18 July 2020, PMLR 119.</mixed-citation></ref><ref id="scirp.132632-ref32"><label>32</label><mixed-citation publication-type="other" xlink:type="simple">Baxter, J. (1997) A Bayesian/Information-Theoretic Model of Learning to Learn via Multiple-Task Sampling. &lt;i&gt;Machine Learning&lt;/i&gt;, 28, 7-39. &lt;br&gt;https://doi.org/10.1023/A:1007327622663</mixed-citation></ref><ref id="scirp.132632-ref33"><label>33</label><mixed-citation publication-type="other" xlink:type="simple">Jain, R., Nagrath, P., Kataria, G., Kaushik, V.S. and Hemanth, D.J. (2020) Pneumonia Detection in Chest X-Ray Images Using Convolutional Neural Networks and Transfer Learning. &lt;i&gt;Measurement&lt;/i&gt;, 165, Article ID: 108046. &lt;br&gt;https://doi.org/10.1016/j.measurement.2020.108046</mixed-citation></ref><ref id="scirp.132632-ref34"><label>34</label><mixed-citation publication-type="other" xlink:type="simple">Dey, N., Zhang, Y.-D., Rajinikanth, V., Pugalenthi, R. and Raja, N. (2021) Customized VGG19 Architecture for Pneumonia Detection in Chest X-Rays&lt;i&gt;. Pattern Recognition Letters&lt;/i&gt;, 143, 67-74. &lt;br&gt;https://doi.org/10.1016/j.patrec.2020.12.010</mixed-citation></ref><ref id="scirp.132632-ref35"><label>35</label><mixed-citation publication-type="other" xlink:type="simple">Jahan, N., Anower, M.S. and Hassan, R. (2021) Automated Diagnosis of Pneumonia from the Classification of Chest X-Ray Images Using the Efficientnet. &lt;i&gt;International Conference on Information and Communication Technology for Sustainable D&lt;/i&gt;&lt;i&gt;e&lt;/i&gt;&lt;i&gt;velopment &lt;/i&gt;(&lt;i&gt;ICICT&lt;/i&gt;4&lt;i&gt;SD&lt;/i&gt;), Dhaka, 27-28 February 2021, 235-239. &lt;br&gt;https://doi.org/10.1109/ICICT4SD50815.2021.9397055</mixed-citation></ref><ref id="scirp.132632-ref36"><label>36</label><mixed-citation publication-type="book" xlink:type="simple">Chatterjee, R., Chatterjee, A. and Halder, R. (2021) An Efficient Pneumonia Detection from the Chest X-Ray Images. In: Prateek, M., &lt;i&gt;et al&lt;/i&gt;., Eds., &lt;i&gt;Proceedings of I&lt;/i&gt;&lt;i&gt;n&lt;/i&gt;&lt;i&gt;ternational Conference on Machine Intelligence and Data Science Applications&lt;/i&gt;: &lt;i&gt;MIDAS&lt;/i&gt; 2020, Springer, Berlin, 779-789. &lt;br&gt;https://doi.org/10.1007/978-981-33-4087-9_63</mixed-citation></ref><ref id="scirp.132632-ref37"><label>37</label><mixed-citation publication-type="other" xlink:type="simple">Zhang, J., Chng, C.B., Chen, X., Wu, C., Zhang, M., Xue, Y. and Jiang, J. (2020) Detection and Classification of Pneumonia from Lung Ultrasound Images. 5&lt;i&gt;th&lt;/i&gt;&lt;i&gt;&lt;sup&gt; &lt;/i&gt;&lt;/sup&gt;&lt;i&gt;Inte&lt;/i&gt;&lt;i&gt;r&lt;/i&gt;&lt;i&gt;national Conference on Communication&lt;/i&gt;,&lt;i&gt; Image and Signal Processing&lt;/i&gt; (&lt;i&gt;CCISP&lt;/i&gt;), Chengdu, 13-15 November 2020, 294-298. &lt;br&gt;https://doi.org/10.1109/CCISP51026.2020.9273469</mixed-citation></ref><ref id="scirp.132632-ref38"><label>38</label><mixed-citation publication-type="other" xlink:type="simple">Chaudhary, S., Sadbhawna, S., Jakhetiya, V., Subudhi, B.N., Baid, U. and Guntuku, S.C. (2021) Detecting COVID-19 and Community-Acquired Pneumonia Using Chest CT Scan Images with Deep Learning. &lt;i&gt;IEEE International Conference on Acou&lt;/i&gt;&lt;i&gt;s&lt;/i&gt;&lt;i&gt;ti&lt;/i&gt;&lt;i&gt;cs&lt;/i&gt;,&lt;i&gt; Speech and Signal Processing &lt;/i&gt;(&lt;i&gt;ICASSP&lt;/i&gt;), Toronto, 6-11 June 2021, 8583-8587. &lt;br&gt;https://doi.org/10.1109/ICASSP39728.2021.9414007</mixed-citation></ref><ref id="scirp.132632-ref39"><label>39</label><mixed-citation publication-type="other" xlink:type="simple">Ko, H., Chung, H., Kim, K.W., Shin, Y.S., Kang, S.J., Lee, J.H., Kim, Y.J., Kim, N.Y., Jung, H.S., Kang, W.S. and Lee, J. (2020) COVID-19 Pneumonia Diagnosis Using a Simple 2D Deep Learning Framework with a Single Chest CT Image: Model Development and Validation. &lt;i&gt;Journal of Medical Internet Research&lt;/i&gt;, 22, e19569. &lt;br&gt;https://doi.org/10.2196/19569</mixed-citation></ref><ref id="scirp.132632-ref40"><label>40</label><mixed-citation publication-type="other" xlink:type="simple">Chaudhary, Y., Mehta, M., Sharma, R., Gupta, D., Khanna, A. and Rodrigues, J.J. (2020) Efficient-CovidNet: Deep Learning-Based COVID-19 Detection from Chest X-Ray Images. &lt;i&gt;IEEE&lt;/i&gt;&lt;i&gt; &lt;/i&gt;&lt;i&gt;International Conference on E&lt;/i&gt;-&lt;i&gt;Health Networking&lt;/i&gt;,&lt;i&gt; Applic&lt;/i&gt;&lt;i&gt;a&lt;/i&gt;&lt;i&gt;tion &amp;&lt;/i&gt;&lt;i&gt; &lt;/i&gt;&lt;i&gt;Services&lt;/i&gt; (&lt;i&gt;HEALTHCOM&lt;/i&gt;), Shenzhen, 1-2 March 2020, 1-6.</mixed-citation></ref><ref id="scirp.132632-ref41"><label>41</label><mixed-citation publication-type="other" xlink:type="simple">Nishio, M., Noguchi, S., Matsuo, H. and Murakami, T.J. (2020) Automatic Classification between COVID-19 Pneumonia, Non-COVID-19 Pneumonia, and the Healthy on Chest X-Ray Image: A Combination of Data Augmentation Methods. &lt;i&gt;Scientific Reports&lt;/i&gt;, 10, Article No. 17532. &lt;br&gt;https://doi.org/10.1038/s41598-020-74539-2</mixed-citation></ref><ref id="scirp.132632-ref42"><label>42</label><mixed-citation publication-type="other" xlink:type="simple">Monshi, M.M.A., Poon, J., Chung, V. and Monshi, F.M. (2021) CovidXrayNet: Optimizing Data Augmentation and CNN Hyperparameters for Improved COVID-19 Detection from CXR. &lt;i&gt;Computers in Biology and Medicine&lt;/i&gt;, 133, Article ID: 104375. &lt;br&gt;https://doi.org/10.1016/j.compbiomed.2021.104375</mixed-citation></ref><ref id="scirp.132632-ref43"><label>43</label><mixed-citation publication-type="other" xlink:type="simple">Al-Zahrani, N.N. and Hedjar, R. (2022) Comparison Study of Deep-Learning Architectures for Classification of Thoracic Pathology. 13&lt;i&gt;th&lt;/i&gt;&lt;i&gt; International Conference on &lt;/i&gt;&lt;i&gt;Information and Communication Systems&lt;/i&gt; (&lt;i&gt;ICICS&lt;/i&gt;), Irbid, 21-23 June 2022, 192-198. &lt;br&gt;https://doi.org/10.1109/ICICS55353.2022.9811150</mixed-citation></ref><ref id="scirp.132632-ref44"><label>44</label><mixed-citation publication-type="other" xlink:type="simple">Bao, G., Chen, H., Liua, T., Gong, G., Yin, Y., Wang, L. and Wang, X. (2022) COVID-MTL: Multitask Learning with Shift3D and Random-Weighted Loss for COVID-19 Diagnosis and Severity Assessment. &lt;i&gt;Pattern Recognition&lt;/i&gt;, 124, Article ID: 108499. &lt;br&gt;https://doi.org/10.1016/j.patcog.2021.108499</mixed-citation></ref><ref id="scirp.132632-ref45"><label>45</label><mixed-citation publication-type="other" xlink:type="simple">Rahman, T., Chowdhury, M.E.H., Khandakar, A., Islam, K.R., Islam, K.F., Mahbub, Z.B., Kadir, M.A. and Kashem, S. (2022) Transfer Learning with Deep Convolutional Neural Network (CNN) for Pneumonia Detection Using Chest X-Ray. &lt;i&gt;A&lt;/i&gt;&lt;i&gt;p&lt;/i&gt;&lt;i&gt;plied Sciences&lt;/i&gt;, 10, Article No. 3233. &lt;br&gt;https://doi.org/10.3390/app10093233</mixed-citation></ref></ref-list></back></article>