Osteoarthritis is a disabling degenerative joint condition characterized by pain, reduced mobility and a negative impact on quality of life. The pathogenesis of osteoarthritis is linked to both excessive joint loading and altered biomechanical patterns, as well as hormonal and cytokine dysregulation. Several risk factors have been identified for osteoarthritis, including age, obesity, gender, previous joint trauma, and occupational and athletic activity [
Total hip and knee arthroplasty is a common elective surgery that significantly improves patients’ quality of life [
This is a retrospective series of cases followed in two hospitals in Kinshasa/DRC: the “Centre Hospitalier Mère et Enfant Monkole (CHME Monkole)” and the “Centre Hospitalier Initiative Plus (CHIP)”. It covered the period from August 13, 2018 to April 07, 2022.
We performed consecutive recruitment of all patients who underwent hip and knee arthroplasty at the two selected medical institutions.
Sociodemographic data: age, sex, profession, marital status.
Clinical data: major complaints, affected joints, BMI, shortening of the lower limbs, comorbidities, diagnosis.
Procedure data: type of anesthesia, duration of surgery, incident, transfusion, type of surgery, approach, intraoperative infection, heparin therapy.
Postoperative physiotherapy data: number of sessions, stockings worn, crutches.
Evolution data: intraoperative, early and late postoperative complications; patient satisfaction.
Ethical and benevolent principles were observed. The data were treated anonymously and in strict confidence. The use of the results of the present study was limited to the strict exploitation related to the objective of the study. The protocol of our study was presented to the ethics committee of the Interdisciplinary Center for Research in Medical Imaging of Kinshasa and we obtained a favorable opinion.
Data analysis was performed using Statistical Package for Social Sciences (SPSS 22.0) software. The descriptive analysis was carried out on the entire study population. The results are expressed as mean ± standard deviation for the quantitative variables, and/or as a percentage for the qualitative variables. Pearson’s chi-square test or Fisher’s exact test was used to compare percentages. The student test was used to compare the means. A p-value of less than 5% was considered the threshold of statistical significance.
As shown in
| Variables | n = 75 | % | |
|---|---|---|---|
| Age | Mean ± SD* | 57.8 ± 13.7 | - |
| ≤49 years old | 20 | 17 | |
| 50 to 63 years old | 23 | 30.7 | |
| ≥64 years old | 32 | 34.7 | |
| Sex | Sex ratio F/M | 1.3 | - |
| Male | 33 | 44 | |
| Women | 42 | 56 | |
| Occupation | Retired | 36 | 48 |
| Employee | 26 | 34.7 | |
| Unemployed | 7 | 9.3 | |
| Not determined | 6 | 8 | |
| Marital status | In union | 34 | 45.3 |
| Only | 41 | 54.7 | |
| Major Complaints | painful hip | 45 | 60 |
| Knee pain | 37 | 16 | |
| Knee deformity | 1 | 1.3 |
*Standard deviation.
Aseptic necrosis of the femoral head (n = 23; 30.7%) and knee arthrosis (n = 19; 25.3%) were the most common radiological diagnoses, as shown in
All patients were operated with a technique of hypotensive anesthesia, of which spinal anesthesia was the most used with 77.3% of cases. Anesthetic incidents (n = 6; 7.9%) were mainly noted in obese patients, including 3 cases of failure, 1 case of respiratory distress and 1 case of hypotension. Compared to the means of knee prosthesis fixity, the cemented TKA was used in 21 patients and the hybrid TKA in 6 patients. At hip level, uncemented THA was the most used with 47 patients and cemented with 1 patient. This different information is provided in
Out of a total of 75 patients, we noted 32 cases of complications (42.7%) including one intraoperative complication (trochanteric fracture) and two immediate postoperative dislocations (n = 1; 3.1%) in the non-obese and early postoperative group (n = 1; 3.1%) in the obese group. We recorded two deaths (one from pulmonary embolism and the other from sepsis) late postoperatively. Lower than,
Obesity, joint trauma and muscle weakness are some of the risk factors for osteoarthritis. These factors increase all the mechanical stresses to which the articular cartilage is subjected. Gender, hormones, metabolic disorders and genetics also play a role. Elderly populations are more frequently and more severely affected by this disease than younger populations [
| Variables | Entire group (n = 75) | BMI* < 30 (n = 33) | BMI* > 30 (n = 42) | p |
|---|---|---|---|---|
| Hip osteoarthritis or coxarthrosis | 13 (17.3) | 2 (6.1) | 11 (26.2) | 0.001 |
| Femoral neck fracture | 12 (21.3) | 5 (15.2) | 7 (16.7) | 0.061 |
| Knee osteoarthritis or gonarthrosis | 19 (25.3) | 6 (18.2) | 13 (30.9) | 0.003 |
| Bilateral knee osteoarthritis | 8 (10.7) | 4 (12.1) | 4 (9.5) | 0.402 |
| Aseptic necrosis of the femoral head | 23 (30.7) | 16 (48.5) | 7 (16.7) | 0.041 |
*Body Mass Index.
| Variables | Entire group n = 75 (%) | BMI < 30 n = 33 (%) | BMI > 30 n = 42 (%) | p | |
|---|---|---|---|---|---|
| Hypotensive anesthesia | AG + IOT* | 9 (12) | 2 (6.1) | 7 (16.7) | > |
| Epidural anesthesia | 4 (5.3) | 2 (6.1) | 2 (4.8) | > | |
| Spinal anesthesia | 58 (77.3) | 25 (75.8) | 33 (78.6) | > | |
| Spinal anesthesia + Sedation | 4 (5.3) | 2 (6.1) | 2 (4.8) | > | |
| Incidents | Failure of spinal anesthesia | 4 (5.3) | 1 (3.0) | 3 (7.1) | > |
| Respiratory distress | 1 (1.3) | 0 | 1 (2.4) | - | |
| Hypotension | 1 (1.3) | 0 | 1 (2.4) | - | |
| Transfusion | 16 (21.3) | 5 (15.2) | 11 (26.2) | > | |
| Means of prosthesis fixity | cemented PTG | 21 (28) | 8 (24.2) | 13 (39.0) | > |
| Hybrid PTG | 6 (8) | 2 (6.1) | 4 (9.5) | > | |
| Uncemented PTH | 47 (62.7) | 22 (66.7) | 25 (59.5) | > | |
| Cemented PTH | 1 (13) | 1 (3.0) | 0 | - | |
| Approach routes | Medial parapatellar knee | 27 (36) | 10 (30.3 | 17 (40.5) | > |
| Lateral hip | 48 (64) | 23 (69.7) | 25 (59.5) | > | |
| Duration of the operation (minutes) | (Mean ± SD) | 127.6 ± 52.5 | 124.6 ± 42.5 | 129.6 ± 51.2 | - |
| Antibiotic therapy (24 h) | 62 (82.7) | 20 (60.6) | 42 (100) | > | |
| Heparin therapy | 71 (94.7) | 29 (87.9) | 42 (100) | > | |
| Physiotherapy (weeks) | (Mean ± SD) | 3.9 ± 1.7 | 3.7 ± 1.9 | 4.9 ± 1.5 | > |
| Compression stocking | 75 (100) | 33 (100) | 42 (100) | - |
*General anesthesia and orotracheal intubation.
| Complications | Entire group n = 32 (%) | BMI < 30 n = 20 (%) | BMI > 30 n = 12 (%) | p | |
|---|---|---|---|---|---|
| Intraoperative | Trochanteric fracture | 1 (3.1) | 0 | 1 (8.3) | - |
| Immediate postoperative | Anemia | 2 (6.2) | 2 (10) | 0 | - |
| Dislocation | 1 (3.1) | 1 (5) | 0 | - | |
| Early postoperative | Anemia | 3 (9.4) | 3 (15) | 0 | - |
| Dislocation | 1 (3.1) | 0 | 1 (8.3) | - | |
| Late postoperative | Pain | 9 (281) | 5 (25) | 4 (33.3) | > |
| knee swelling | 2 (6.2) | 2 (10) | 0 | - | |
| Urinary tract infection | 10 (3.1) | 5 (25) | 5 (42.1) | > | |
| Pulmonary embolism | 1 (31.2) | 1 (5) | 0 | - | |
| Death | 2 (6.2) | 1 (5) | 1 (8.3) | > | |
Worldwide, estimates show that 10% of men and 18% of women over the age of 60 suffer from symptomatic osteoarthritis, including moderate and severe forms [
Obesity is closely linked to the onset and progression of osteoarthritis and is often considered a modifiable risk factor. In patients with a high body mass index (BMI), especially ≥40 kg/m2, the surgeon suggests that it may be important to lower the BMI (by losing weight) before joint replacement surgery to avoid complications intra- and postoperatively and to make surgeries manageable [
Arthroplasties surgery in the obese patient may be technically more difficult and carries a risk of additional complications. Substantial weight loss before undertaking total knee replacement surgery is advised because obesity increases operative time, length of stay, and hospital costs, as well as the risk of deep infection, revision, and poor positioning of the joints components [
Of the 75 patients reviewed 6.12 months after hip and knee prosthesis, 9 patients (obese and non-obese) complained of pain during the dry season. Our obese patients made good progress and resumed their daily activities. Of our 75 patients, 10 were not evaluated (13.33%), 38 were very satisfied (50.67%), 20 satisfied (26.67%), 5 not very satisfied (6.67%), 2 not satisfied (2.67%). In our study, we did not note any significant difference in the postoperative evolution of obese and non-obese patients. This correlates with most publications.
Obesity is potentially preventable and reversible, unlike osteoarthritis, and should, if possible, be treated before considering joint replacement. The indications for arthroplasty in this study are dominated by non-traumatic pathologies of the knee and of the hip (osteoarthritis and aseptic necrosis). Most patients are overweight, including obesity. The evolution is favorable in the vast majority of cases.
We had a small sample size which was not very representative. We were also not able to include the satisfaction of patients after their therapeutic treatment.
Consent was obtained or waived by all participants in this study. All authors have confirmed that this study did not involve animal subjects or tissue.
Contribution of AuthorsAME: work design, work writing and surgery actress. JNK: management and surgical operator. GEN: work proofreading. TKM: statistical analyses and work writing. LMB: proofreading of the work.
Conflicts of InterestThe authors declare no conflicts of interest.
Ekomisa, A.M., Kumasamba, J.N., Ntsambi, G.E., Mazoba, T.K. and Bakumobatane, L.M. (2023) Arthroplasty Practice in a Resource-Limited Setting: Indications, Nutritional Profile of Patients and Evolution in a Consecutive 2-Year Series. Open Access Library Journal, 10: e10809. https://doi.org/10.4236/oalib.1110809
AG: general anesthesia
IOT: orotracheal intubation
THA: Total Hip Arthroplasty
TKA: Total Knee Arthroplasty
X ± SD: Mean ± Standard deviation