<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article  PUBLIC "-//NLM//DTD Journal Publishing DTD v3.0 20080202//EN" "http://dtd.nlm.nih.gov/publishing/3.0/journalpublishing3.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="3.0" xml:lang="en" article-type="research article"><front><journal-meta><journal-id journal-id-type="publisher-id">JBM</journal-id><journal-title-group><journal-title>Journal of Biosciences and Medicines</journal-title></journal-title-group><issn pub-type="epub">2327-5081</issn><publisher><publisher-name>Scientific Research Publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.4236/jbm.2023.117013</article-id><article-id pub-id-type="publisher-id">JBM-126425</article-id><article-categories><subj-group subj-group-type="heading"><subject>Articles</subject></subj-group><subj-group subj-group-type="Discipline-v2"><subject>Biomedical&amp;Life Sciences</subject></subj-group></article-categories><title-group><article-title>
 
 
  Description of the Factors Associated with Trigger Finger in Patients Treated at Petroleos Mexicanos “Pemex”
 
</article-title></title-group><contrib-group><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Fernando</surname><given-names>Barbosa-Villarreal</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Cuahutémoc</surname><given-names>Márquez-Espriella</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Rodrigo</surname><given-names>Dávila-Díaz</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Marco</surname><given-names>A. Cuervo-Vergara</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Blanca</surname><given-names>Y. Arambula-Sánchez</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Alberto</surname><given-names>I. Cahuana-Quispe</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Victor</surname><given-names>A. Esquivel-Chávez</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Carlos</surname><given-names>E. García-Córdova</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Ana</surname><given-names>P. Campollo-López</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Mauricio</surname><given-names>Gutierrez-Alvarez</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="corresp" rid="cor1"><sup>*</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Jesus</surname><given-names>R. García-Corral</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Alfredo</surname><given-names>Chama-Naranjo</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Daniel</surname><given-names>de Luna-Gallardo</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Ricardo</surname><given-names>A. Pulido-López</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Isaac</surname><given-names>F. Recio-España</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Esteban</surname><given-names>I. Campos-Serna</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Carlos</surname><given-names>I. Navarro-Delgadillo</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Victor</surname><given-names>H. Avalos-Gómez</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Alejandro</surname><given-names>Cruz-Zarate</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>José</surname><given-names>C. Martínez-López</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib></contrib-group><aff id="aff1"><addr-line>Department of Plastic and Reconstructive Surgery, Hospital Central Sur Petróleos Mexicanos, Mexico City, Mexico</addr-line></aff><pub-date pub-type="epub"><day>06</day><month>07</month><year>2023</year></pub-date><volume>11</volume><issue>07</issue><fpage>151</fpage><lpage>159</lpage><history><date date-type="received"><day>24,</day>	<month>May</month>	<year>2023</year></date><date date-type="rev-recd"><day>17,</day>	<month>July</month>	<year>2023</year>	</date><date date-type="accepted"><day>20,</day>	<month>July</month>	<year>2023</year></date></history><permissions><copyright-statement>&#169; Copyright  2014 by authors and Scientific Research Publishing Inc. </copyright-statement><copyright-year>2014</copyright-year><license><license-p>This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/</license-p></license></permissions><abstract><p>
 
 
  Background: The trigger finger, also known as stenosing tenosynovitis of the flexor tendon, is a common cause of hand disability; This can result in significant limitations in certain daily living activities. It is possible to treat this condition with conservative or surgical methods. 
  Methods: This is a retrospective, observational, cross-sectional and descriptive study. The source population consisted of all patients with a diagnosis of trigger finger who had been treated in the department of plastic and reconstructive surgery of our institution between 2020 and 2023. The primary objective of this study is to determine the prevalence and characterize the clinical and surgical characteristics of the population affected by trigger finger in our hospital. 
  Results: The total population was 237 patients, of which 165 were women (70%) and 72 men (30%). The most affected hand was the right hand, with a total of 158 patients (67%). In the right hand, the middle finger was the most affected (45%). Of the 237 patients, 80 of them had obesity (34%), 86 had type 2 diabetes mellitus (36%), 95 had systemic arterial hypertension (40%). Open technique was performed in 190 (80%) patients, while percutaneous technique was performed in 47 (20%) of them. 
  Conclusion: The female sex was twice as frequent, and the middle finger and thumb were the most affected. Most of the patients received surgical treatment with open approach and percutaneous approach in 20% of them.
 
</p></abstract><kwd-group><kwd>Trigger Finger</kwd><kwd> Tendinopathy</kwd></kwd-group></article-meta></front><body><sec id="s1"><title>1. Introduction</title><p>The trigger finger (TF), also known as stenosing tenosynovitis of the flexor tendon, is a common cause of hand disability. The prevalence of this pathology ranges from 1% to 3%, with an incidence of 2% to 3%. It has two peaks of presentation throughout life: the first is in patients younger than eight years of age, and the second is between the fifth and sixth decades of life [<xref ref-type="bibr" rid="scirp.126425-ref1">1</xref>] . The presence of TF can result in significant limitations in certain daily living activities, such as the holding of objects, counting coins, or buttoning of buttons [<xref ref-type="bibr" rid="scirp.126425-ref2">2</xref>] .</p><p>TF has a female predilection and is two to six times more common in women than in men. It occurs most frequently in the middle and ring fingers of the dominant hand, followed by the index and little fingers in that order [<xref ref-type="bibr" rid="scirp.126425-ref1">1</xref>] [<xref ref-type="bibr" rid="scirp.126425-ref3">3</xref>] .</p><p>Although the etiology is unknown, some theories have been described, and some predisposing factors are known [<xref ref-type="bibr" rid="scirp.126425-ref3">3</xref>] . Risk factors for this entity include genetic predisposition, systemic diseases (diabetes mellitus, systemic arterial hypertension, and dyslipidemia), and repetitive gripping activities causing mechanical irritation of the first pulley tendon (A1). Several hand diseases, such as Quervain’s tenosynovitis, Dupuytren’s contracture, and carpal tunnel syndrome, have a higher incidence of TF [<xref ref-type="bibr" rid="scirp.126425-ref3">3</xref>] . However, systemic diseases such as hypothyroidism, rheumatoid arthritis, mucopolysaccharidosis, carpal tunnel syndrome, and diabetes mellitus are associated with a higher incidence and severity of TF. The prevalence of TF in patients with type 2 diabetes mellitus ranges from 5 to 20%, and the incidence of TF is 10%. Glycosylated hemoglobin levels greater than 7 have been positively correlated with the development and severity of TF [<xref ref-type="bibr" rid="scirp.126425-ref1">1</xref>] .</p><p>The clinical manifestations of TF are varied, ranging from moderate pain to contractures of the fingers involved, as a result of the narrowing and widening of the tendon sheath [<xref ref-type="bibr" rid="scirp.126425-ref3">3</xref>] . A diagnosis is established through a thorough examination of the patient’s medical history and physical examination. The patient may experience pain at the metacarpophalangeal level, functional limitation, flexion locking, locking sensation, or entrapment with active range of motion of the finger (<xref ref-type="fig" rid="fig1">Figure 1</xref> and <xref ref-type="fig" rid="fig2">Figure 2</xref>).</p><p>It is possible to treat this condition with conservative or surgical methods. The initial treatment regimen consists of local administration of corticosteroids, oral administration of non-steroidal anti-inflammatory drugs, and immobilization of the affected phalanges. Diabetic patients are required to maintain glucose levels within normal ranges [<xref ref-type="bibr" rid="scirp.126425-ref4">4</xref>] . One study compared splinting of the metacarpophalangeal joint with splinting of the proximal interphalangeal joint. Both were effective in reducing pain and disability and improving symptoms. However, splinting the proximal interphalangeal joint was more effective, suggesting that</p><p>immobilization of the affected finger is a viable treatment [<xref ref-type="bibr" rid="scirp.126425-ref2">2</xref>] [<xref ref-type="bibr" rid="scirp.126425-ref5">5</xref>] .</p><p>Howard first described corticosteroid injection into the flexor tendon sheath in 1953, with variable success rates in subsequent literature. The majority of authors agree that acceptable success rates can be achieved with a minimum of three injections. Seigerman et al. reported that pain relief occurs three weeks after the injection [<xref ref-type="bibr" rid="scirp.126425-ref6">6</xref>] .</p><p>Surgery is indicated when conservative treatment is unsuccessful. The open surgical approach employs direct visualization and division or release of the A1 pulley, with success rate exceeding 95%. The most common complications include are persistent pain, swelling, and persistent or recurrent triggering [<xref ref-type="bibr" rid="scirp.126425-ref3">3</xref>] (<xref ref-type="fig" rid="fig3">Figure 3</xref>). The percutaneous surgical technique (<xref ref-type="fig" rid="fig4">Figure 4</xref>), described in 1958</p><p>by Lorthioir with 94% effectiveness, has the advantages of minimally invasive surgery (less postoperative pain, less trauma, among others) and a lower cost [<xref ref-type="bibr" rid="scirp.126425-ref3">3</xref>] .</p><p>The final treatment decision depends on the preference of the patient and the surgeon’s individual assessment of the severity of each case. Even observation may be an option. The spontaneous resolution of TF has been seen within one year, which is probably attributed to remodeling of the pulley and decreased inflammation due to lifestyle changes [<xref ref-type="bibr" rid="scirp.126425-ref3">3</xref>] [<xref ref-type="bibr" rid="scirp.126425-ref7">7</xref>] .</p><p>The aim of the present work is to review the prevalence and epidemiological characteristics of patients diagnosed with TF in our hospital.</p></sec><sec id="s2"><title>2. Methodology</title><p>This is a retrospective, observational, cross-sectional and descriptive study. The source population consisted of all patients with a diagnosis of trigger finger who had been treated in the department of plastic and reconstructive surgery of our institution between 2020 and 2023. The inclusion criteria were as follows: patients with a diagnosis of trigger finger between 2020 and 2023, who underwent immediate postoperative clinical follow-up, and who had a complete clinical record.</p><p>The only exclusion criterion used was not having a complete clinical record. In 2020 and 2023, a total of 239 patients were obtained, through a non-probabilistic convenience sampling, who had been treated for trigger finger in our institution. Two patients were excluded from the study because they did not receive post-surgical follow-up. The study enrolled a total of 237 participants.</p><p>The primary objective of this study is to determine the prevalence and characterize the clinical and surgical characteristics of the population affected by trigger finger in our hospital.</p><p>For nominal variables, a frequency analysis was performed. Kolmogorov-Smirnov normality tests were applied, and then mean and deviation were used to describe normally distributed numerical variables and median and range to describe non-normally distributed numerical variables.</p><p>Statistical analysis and normality tests were obtained with the jamovi program version 2.3.18. The article was written based on the STROBE guidelines for observational reports. A search for articles was carried out in PubMed, Cochrane Library, Google Scholar, and a synthesis of current knowledge.</p><p>In accordance with the ethical norms of the Declaration of Helsinki and article 17 of the Regulations of the General Law of Health on Health Research, the participation of patients in this study involves one type of risk: No Risk.</p><p>The protocol was approved by ethic and bioethics commit at Pemex. The information collected will be stored in a database and the identity of the research subject will be protected by entering a consecutive number. This database will only have access to the researchers and will remain under password in the computer of the head of the plastic and reconstructive surgery service, with the data obtained this study will be carried out, and it is planned to save this information for future studies, so it will not be discarded and will be completed with future research subjects. It does not require informed consent because it is a descriptive cross-sectional study where the data will be taken from the electronic clinical record.</p></sec><sec id="s3"><title>3. Results</title><p>The total population was 237 patients, of which 165 were women (70%) and 72 men (30%). The minimum age was 26 years and maximum 104 years, with a mean of 62 years (<xref ref-type="table" rid="table1">Table 1</xref> and <xref ref-type="table" rid="table2">Table 2</xref>).</p><p>The most affected hand was the right hand with a total of 158 patients (67%), while the left hand was affected in 79 patients (33%). In the right hand the middle finger was the most affected (45%), followed by the thumb (24%), ring finger (19%), index finger (8%) and little finger (4%). In the left hand, the thumb had the greatest involvement (34%), followed by the middle finger (32%), ring finger (24%), index finger (6%) and little finger (4%) (Graphic 1).</p><p>Of the 237 patients, 80 of them had obesity (34%), 86 had type 2 diabetes mellitus (36%), 95 had systemic arterial hypertension (40%), 43 had a positive history of smoking (18%) and 24 of them for alcohol consumption (10%) (Graphic 2).</p><table-wrap id="table1" ><label><xref ref-type="table" rid="table1">Table 1</xref></label><caption><title> Sex distribution of patients with trigger finger</title></caption><table><tbody><thead><tr><th align="center" valign="middle" ></th><th align="center" valign="middle" >Population (N = 237)</th></tr></thead><tr><td align="center" valign="middle" >Woman</td><td align="center" valign="middle" >165 (70%)</td></tr><tr><td align="center" valign="middle" >Man</td><td align="center" valign="middle" >72 (30%)</td></tr></tbody></table></table-wrap><table-wrap id="table2" ><label><xref ref-type="table" rid="table2">Table 2</xref></label><caption><title> Age distribution of patients with trigger finger</title></caption><table><tbody><thead><tr><th align="center" valign="middle" ></th><th align="center" valign="middle" >Minimum</th><th align="center" valign="middle" >Maximum</th><th align="center" valign="middle" >Average</th></tr></thead><tr><td align="center" valign="middle" >Age</td><td align="center" valign="middle" >26</td><td align="center" valign="middle" >104</td><td align="center" valign="middle" >62</td></tr></tbody></table></table-wrap><disp-formula id="scirp.126425-formula1"><graphic  xlink:href="//html.scirp.org/file/13-2152150x6.png?20230821090936747"  xlink:type="simple"/></disp-formula><p>Graphic 1. Frequency of hand and finger involvement in patients with trigger finger.</p><disp-formula id="scirp.126425-formula2"><graphic  xlink:href="//html.scirp.org/file/13-2152150x7.png?20230821090936747"  xlink:type="simple"/></disp-formula><p>T2DM: type 2 diabetes mellitus, SAH: systemic arterial hypertension.</p><p>Graphic 2. Frequency of trigger finger associated with comorbidities.</p><table-wrap id="table3" ><label><xref ref-type="table" rid="table3">Table 3</xref></label><caption><title> Frequency of surgical techniques performed for the treatment of trigger finger</title></caption><table><tbody><thead><tr><th align="center" valign="middle" ></th><th align="center" valign="middle" >N = 237</th></tr></thead><tr><td align="center" valign="middle" >Infiltration</td><td align="center" valign="middle" >78 (33%)</td></tr><tr><td align="center" valign="middle" >NSAID</td><td align="center" valign="middle" >138 (58%)</td></tr><tr><td align="center" valign="middle" >Technique</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Open</td><td align="center" valign="middle" >190 (80%)</td></tr><tr><td align="center" valign="middle" >Percutaneous</td><td align="center" valign="middle" >47 (20%)</td></tr></tbody></table></table-wrap><p>NSAID: nonsteroidal anti-inflammatory drugs.</p><p>Thirty-three percent of patients (n = 78) received corticosteroid infiltration and 58% (n = 138) were given oral nonsteroidal anti-inflammatory drugs prior to surgical treatment. Open technique was performed in 190 (80%) patients, while percutaneous technique was performed in 47 (20%) of them (<xref ref-type="table" rid="table3">Table 3</xref>).</p></sec><sec id="s4"><title>4. Discussion</title><p>In our case series there was a higher prevalence in women and the involvement of the right hand (dominant hand in most of the population) coincides with those described in the literature. Blough et al. described a 2 - 6 times greater involvement in the female population [<xref ref-type="bibr" rid="scirp.126425-ref3">3</xref>] , however, Neto et al. observed that it is only twice as great in women, which is consistent with what was found in our population [<xref ref-type="bibr" rid="scirp.126425-ref8">8</xref>] . Another finding that was found in our population is the greater frequency of involvement of the middle finger and thumb, while in the literature the most affected fingers are the middle and ring fingers, as Lunsford et al. [<xref ref-type="bibr" rid="scirp.126425-ref2">2</xref>] . Gil et al., also describe the middle and ring finger as the most affected [<xref ref-type="bibr" rid="scirp.126425-ref1">1</xref>] . However, Blough et al. report greater involvement of the ring finger followed by the middle finger [<xref ref-type="bibr" rid="scirp.126425-ref3">3</xref>] .</p><p>In our study, a non-negligible percentage suffered from systemic diseases such as diabetes mellitus, arterial hypertension and obesity, a finding that coincides with those described in the literature. Blough et al. emphasize that diseases involving metabolic syndrome, especially diabetes mellitus and hypertension, are known risk factors [<xref ref-type="bibr" rid="scirp.126425-ref3">3</xref>] . Neto et al., in their retrospective study state that 68% of the patients had systemic arterial hypertension and 36% had type 2 diabetes mellitus, the latter finding is identical to that found in our population [<xref ref-type="bibr" rid="scirp.126425-ref3">3</xref>] [<xref ref-type="bibr" rid="scirp.126425-ref8">8</xref>] .</p><p>Most patients received medical treatment with nonsteroidal anti-inflammatory drugs and corticosteroid infiltration prior to surgical treatment. The percutaneous technique was performed in 19.8% of the patients and the open technique in 80.2% of them.</p><p>As our study is descriptive and observational, it is limited by the fact that it is not possible to conduct a random sample, which could lead to biases. However, new lines of research can be opened with randomized samples.</p></sec><sec id="s5"><title>5. Conclusion</title><p>In our case series there are similarities with respect to the epidemiology reported in the literature, however there are remarkable differences in the frequency of involvement. The female sex was twice as frequent and the middle finger and thumb were the most affected. Most of the patients received surgical treatment with open approach and percutaneous approach in 20% of them.</p></sec><sec id="s6"><title>Conflicts of Interest</title><p>The authors declare no conflicts of interest regarding the publication of this paper.</p></sec><sec id="s7"><title>Cite this paper</title><p>Barbosa-Villarreal, F., M&#225;rquez-Espriella, C., D&#225;vila-D&#237;az, R., Cuervo-Vergara, M.A., Arambula-S&#225;nchez, B.Y., Cahuana-Quispe, A.I., Esquivel-Ch&#225;vez, V.A., Garc&#237;a-C&#243;rdova, C.E., Campollo-L&#243;pez, A.P., Gutierrez-Alvarez, M., Garc&#237;a-Corral, J.R., Chama-Naranjo, A., de Luna-Gallardo, D., Pulido-L&#243;pez, R.A., Recio-Espa&#241;a, I.F., Campos-Serna, E.I., Navarro-Delgadillo, C.I., Mart&#237;nez-L&#243;pez, J.C., Avalos-G&#243;mez, V.H. and Cruz-Zarate, A. (2023) Description of the Factors Associated with Trigger Finger in Patients Treated at Petroleos Mexicanos “Pemex”. Journal of Biosciences and Medicines, 11, 151-159. https://doi.org/10.4236/jbm.2023.117013</p></sec></body><back><ref-list><title>References</title><ref id="scirp.126425-ref1"><label>1</label><mixed-citation publication-type="other" xlink:type="simple">Gil, J.A., Hresko, A.M. and Weiss, A.C. (2020) Current Concepts in the Management of Trigger Finger in Adults. Journal of the American Academy of Orthopaedic Surgeons, 28, e642-e650. https://doi.org/10.5435/JAAOS-D-19-00614</mixed-citation></ref><ref id="scirp.126425-ref2"><label>2</label><mixed-citation publication-type="other" xlink:type="simple">Lunsford, D., Valdes, K. and Hengy, S. (2019) Conservative Management of Trigger Finger: A Systematic Review. Journal of Hand Therapy, 32, 212-221. https://doi.org/10.1016/j.jht.2017.10.016</mixed-citation></ref><ref id="scirp.126425-ref3"><label>3</label><mixed-citation publication-type="other" xlink:type="simple">Blough, C., Najdawi, J. and Kuschner, S. 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