<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article  PUBLIC "-//NLM//DTD Journal Publishing DTD v3.0 20080202//EN" "http://dtd.nlm.nih.gov/publishing/3.0/journalpublishing3.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="3.0" xml:lang="en" article-type="research article"><front><journal-meta><journal-id journal-id-type="publisher-id">CRCM</journal-id><journal-title-group><journal-title>Case Reports in Clinical Medicine</journal-title></journal-title-group><issn pub-type="epub">2325-7075</issn><publisher><publisher-name>Scientific Research Publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.4236/crcm.2022.1112071</article-id><article-id pub-id-type="publisher-id">CRCM-122046</article-id><article-categories><subj-group subj-group-type="heading"><subject>Articles</subject></subj-group><subj-group subj-group-type="Discipline-v2"><subject>Medicine&amp;Healthcare</subject></subj-group></article-categories><title-group><article-title>
 
 
  The Case Report on the Effectiveness of Infrared Light on Acid Burn Victim
 
</article-title></title-group><contrib-group><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Maha</surname><given-names>Farhina</given-names></name><xref ref-type="aff" rid="aff1"><sub>1</sub></xref><xref ref-type="corresp" rid="cor1"><sup>*</sup></xref></contrib></contrib-group><aff id="aff1"><label>1</label><addr-line>Plastic Surgery Department, Dr. Ruth K. M. Pau Civil Hospital, Karachi, Pakistan</addr-line></aff><pub-date pub-type="epub"><day>07</day><month>12</month><year>2022</year></pub-date><volume>11</volume><issue>12</issue><fpage>527</fpage><lpage>533</lpage><history><date date-type="received"><day>14,</day>	<month>November</month>	<year>2022</year></date><date date-type="rev-recd"><day>26,</day>	<month>December</month>	<year>2022</year>	</date><date date-type="accepted"><day>29,</day>	<month>December</month>	<year>2022</year></date></history><permissions><copyright-statement>&#169; Copyright  2014 by authors and Scientific Research Publishing Inc. </copyright-statement><copyright-year>2014</copyright-year><license><license-p>This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/</license-p></license></permissions><abstract><p>
 
 
  Burn injuries are common in Pakistan. However, most people are reluctant to have infrared treatment for their wounds. This study investigated the efficacy of infrared treatment on burn wounds. The procedure involved a burn victim who had sustained acid burns to the neck and face. Nectrotomy was done to remove dead tissue from the burn wound, and after treatment, Low-Level Light was used to reduce pain and enhance healing in the patient. Initial results showed mild hypertrophic scars, no stiffness. Post-operation therapy included physical training regimens and massage. The patient showed satisfactory results and felt less tightness in neck movements by the following treatment. The article concludes by showing that infrared light promoted repair and regrowth at a cellular level.
 
</p></abstract><kwd-group><kwd>Infrared Therapy</kwd><kwd> Acid Burns</kwd><kwd> Photobiomodulation</kwd><kwd> Low Light Laser Therapy</kwd><kwd> Red Light</kwd></kwd-group></article-meta></front><body><sec id="s1"><title>1. Introduction</title><p>Every year, burns drive tens of thousands of individuals to the hospital’s emergency unit and can seriously harm the skin. To a certain degree, burns take longer to heal and result in skin scarring, formation of neck contractures and may limit the Daily activity of life, if not treated properly. Appropriately intervention is, therefore, crucial to lessen the potential damage that a burn could cause. Full-thickness skin burns benefit from earlier excision and wound grafting, while partial burns must not need much intervention. Since the severity of the injury is concealed under the skin, choosing the right course of action can be challenging. To boost accuracy, imaging techniques such as forward-looking infrared (FLIR) look promising.</p></sec><sec id="s2"><title>2. Low-Level Light Therapy in Burns Treatment</title><p>Clinical evaluation has a poor degree of accuracy when estimating burn severity. Infrared light is initially used to map the depth of a burn wound. Previous studies have found a link between the burn’s lowest temperature and the final scar depth, but they only take a small portion of the burn into account [<xref ref-type="bibr" rid="scirp.122046-ref1">1</xref>]. Other studies have also established the effectiveness of photobiomodulation in cell regrowth and healing in burn wounds [<xref ref-type="bibr" rid="scirp.122046-ref2">2</xref>]. Studies were carried out on infrared therapy in dermatology and hair restoration, where the light was used to stimulate cell regeneration and hair growth [<xref ref-type="bibr" rid="scirp.122046-ref3">3</xref>]. Other studies have investigated how infrared light promotes skin microcirculation and healing while preventing scarring [<xref ref-type="bibr" rid="scirp.122046-ref4">4</xref>] in acid burns.</p><p>In this study, the patient was a burn victim that sustained acid burn Pseudo-Escher wound (<xref ref-type="fig" rid="fig1">Figure 1</xref>). However, before any rehabilitation, the patient underwent multiple surgical procedures for the removal of dead tissue to the affected areas. Therefore the duration of his stay at the Hospital for recovery was approximately 1 month period. As for the proceeding of the treatment goes, the patient was referred for rehabilitation for maintaining the range of motion and prevention of contracture formation. Patient underwent 10 minutes of infrared therapy per session, accompanied with 15 minutes of massage on the scared areas of the face and neck and 15 - 20 min session of stretches and exercise, four times a week during six months of period, resulting in less formation of hypertrophic scars and no stiffness. After the therapy was done, the patient could efficiently perform neck movements. There was less inflammation and stiffness, which we attributed to infrared therapy. Photobiomodulation has been used to reduce inflammation, improve wound healing (<xref ref-type="fig" rid="fig2">Figure 2</xref>, <xref ref-type="fig" rid="fig3">Figure 3</xref>), and relieve pain in diabetic patients [<xref ref-type="bibr" rid="scirp.122046-ref2">2</xref>]. The process refers to inducing reactions at the cellular level by exposing the cells to “low-level or near-infrared light” [<xref ref-type="bibr" rid="scirp.122046-ref3">3</xref>]. According to Erin Dodd et al. (2017), introducing this red light has therapeutic effects, such as reducing pro-inflammatory cytokines. This therapy reduces inflammation which</p><p>would delay healing in wounds. The heating process promotes the repair of tissues hence enhancing healing. For many decades, infrared treatment has been employed in various settings. It is one of several cutting-edge treatments that aid individuals who are experiencing pain and injury. Many light wavelengths, around 780 nm, and 1000 μm, are used in infrared therapy and focus on the body’s wounded or inflamed areas.</p><p>Focusing on inflamed areas, we used infrared light on skin tissue since it can reach deep within the layers of the skin. Photo-biostimulation occurs when living flesh is subjected to light energy through the absorption of respiratory chain components. The advantage of infrared light is that it will not harm the skin, unlike ultraviolet light. In reality, infrared light promotes cell regeneration as well as blood circulation. The heat that individuals experience when subjected to the sun’s rays is infrared light, and human bodies radiate it too. Acid burns result in facial disfigurement and scarring to the victims (<xref ref-type="fig" rid="fig2">Figure 2</xref>) [<xref ref-type="bibr" rid="scirp.122046-ref5">5</xref>]. In burn victims, treatment using infrared light has shown lower loss of energy, lower infection rates, and shorter healing time [<xref ref-type="bibr" rid="scirp.122046-ref6">6</xref>].</p><p>However, it is not only the low infection rates and shorter healing time that make IR favorable. For example, infrared therapy has been utilized for decades to treat wounds due to its calming properties. Numerous studies have demonstrated that this kind of therapy speeds up the healing of wounds. According to research, infrared can enhance circulation in numerous human tissues and organs, including the skin. It can promote healthy sleep, guard against oxidative stress, and lessen inflammation and pain. Infrared’s inflammation-reducing properties have led to its use in several treatment regimens, including the treatment of COVID-19 [<xref ref-type="bibr" rid="scirp.122046-ref7">7</xref>]. Red light, in this case, provides a non-invasive and affordable method to treat various inflammatory conditions. The authors demonstrate that the TLR-4-reliant pathway for inflammation response, which is thought to be responsible for the initiation of cytokine storms among COVID-19 patients, is significantly reduced due to subjection to two 10-min high-frequency bouts of infra-red light every day. The treatment, which happened over 48 hours, reduced inflammation at a cellular level. Besides reducing inflammation, IR therapy encourages tissue regeneration and wound healing, speeding the recovery of sores and slow-healing of wounds. People have used electricity and magnetism with a variety of outcomes. Transcutaneous electrical stimulation (TENS) was created in 1975 to alleviate chronic pain [<xref ref-type="bibr" rid="scirp.122046-ref8">8</xref>]. Infrared treatment was recently found to enhance wound healing, lessen arthritis pain, increase endorphin levels, and bioactivate neuromodulators.</p></sec><sec id="s3"><title>3. Methods</title><p>The patient came for 1 scheduled hour of rehabilitation management four times in a week for six months after sustaining an acid burn on the left side of the face, neck (<xref ref-type="fig" rid="fig1">Figure 1</xref>) and the posterior shoulder as well as the back area (<xref ref-type="fig" rid="fig4">Figure 4</xref>) and was treated using infrared therapy, with massage on the face, neck and shoulder and stretching exercises on the neck. The burn was caused by acid,</p><p>which had been introduced and burned several sections of the skin on the neck face and shoulder. The patient underwent general cardiovascular and respiratory organs examination as well as functions of other vital organs. The specialists performed several surgical procedures when the patient arrived at the hospital. First, a debridement was performed on the wounds to avoid secondary necrosis and hasten the rejection of necrotic issues. Once it was done, the wound was covered with chemotherapeutic substances. During that time period range of motion was being performed after patient was discharged, his rehabilitation session included infrared light treatment, the lamps were placed between 45 and 75 centimeters from the patient’s skin, and each session lasted between 10 - 15 minutes. The neck’s range of motion was measured by Hand-Held Goniometer every week.</p><p>Apart from IR light treatment, we searched for articles using online databases such as EBSCO, Google Scholar, and ProQuest to be used in discussing the case. Comparing and evaluating polarized light’s benefits on musculoskeletal, cutaneous, and burns produced results that are both on par with our case and treatment.</p></sec><sec id="s4"><title>4. Results</title><p>The treatment resulted in less hypertrophic scars and no stiffness. Post-operation (<xref ref-type="fig" rid="fig2">Figure 2</xref>, <xref ref-type="fig" rid="fig3">Figure 3</xref>) therapy included physical training regimens and massage. The patient showed satisfactory results and felt less stretched in neck movements following the treatment. On the assessment of neck ranges, the results were documented as follows: there was a 75-degree flexion, 80-degree extension, 45-degree lateral rotation on both sides, and 80 degrees on both sides.</p></sec><sec id="s5"><title>5. Discussion</title><p>The technologies of infrared radiation are being used in multiple treatments worldwide. The management of acid burns in patients remains a challenge in Pakistan. Even though infrared is used in treating burn victims, using red light on burn wounds is still met with resistance in the country since people are scared it might burn the victim. Several studies have shown the efficacy of infrared therapy on burn victims. Acid burns and related injuries continue to cause disability and death globally. For example, infrared light has been used to treat musculoskeletal burns and skin issues [<xref ref-type="bibr" rid="scirp.122046-ref9">9</xref>]. The patient showed improvements in healing with no hypertrophic scars. Infrared therapy aids healing in the skin by preventing inflammation.</p><p>Indeed, IR therapy prevents inflammation since it works on acid burns at a cellular level. In biological systems, the photoreceptor or molecular chromophores absorb photons from the infrared “using electron absorption bands” in the cells [<xref ref-type="bibr" rid="scirp.122046-ref10">10</xref>]. Accordingly, scattering and absorption of infrared light depend on its wavelength, determining its absorption, as well as chromosomes of the tissue. For instance, melanin and hemoglobin have higher absorption rates with shorter wavelengths than 600 nm. The patient showed cell regeneration through infrared therapy in red and near-infrared lighting. The mechanism of light absorption depended on visible monochromatic as well as NIR radiation of the cell respiratory chain (4).</p><p>According to Tsagkaris et al. (2022), infrared works at a molecular level through “tissues, body fluids, and the molecules that circulate in them” (335) [<xref ref-type="bibr" rid="scirp.122046-ref11">11</xref>]. Thus the effect of this therapy depends on the tissue’s composition as well as the molecules found within the body fluids (ibid). When the cells are subjected to heat, IR interacts with molecules to alter cell membranes through increasing intracellular Ca<sup>2+</sup> levels [<xref ref-type="bibr" rid="scirp.122046-ref11">11</xref>]. Consequently, this permeability and alteration promotes growth, thus promoting cellular repair in acid burns. Thus, working at a molecular level, this therapy suits acid burn victims, particularly in Pakistan.</p></sec><sec id="s6"><title>6. Strength of the Study</title><p>As far as we know, this is one of Pakistan’s first studies on the infrared treatment of acid burn victims. The study period was sufficient (6 months) to gain enough data from the patient and was integrated with an available scholarship for the conclusions. The outcomes of this study present a new avenue and perspective on the treatment of acid burns since IR is an effective therapy for acid burns.</p></sec><sec id="s7"><title>7. Limitations of the Study</title><p>The study’s main limitation is that it has no provision for counseling burn victims as they go through lots of depression, motivating them for the treatment, and working on their self-esteem plus the lack of awareness among society about the rehabilitation process and lack of resources. Lack of funding creates difficulty in the treatments. Given societal attitudes about red lights in the country, such study findings might take a long time to be adopted. In addition, the study relies on data from a single patient and thus does not offer comparative or controls. Future studies would therefore involve a high number of patients that present different variables.</p></sec><sec id="s8"><title>8. Conclusion</title><p>Although many people are still skeptical about IR therapy in Pakistan, research shows it to be an effective therapy for acid burn treatment. This treatment promotes repair at a cellular level, thus preventing scarring. The light helps restructure cell membranes, thus helping circulate molecules within tissue fluids. Healing following this therapy also resulted in less stiffness in the patient. The therapy helps in reducing inflammation, which aids in rapid healing in patients. Since acid burns are hard to heal and can lead to much scarring, regimens such as infrared are recommended for burn patients. Using this regimen led to less scarring in the patient and easy movement following healing. Given the effectiveness of the therapy, further research is necessary, especially in promoting a change of attitudes toward such treatments.</p></sec><sec id="s9"><title>Conflicts of Interest</title><p>The author declares no conflicts of interest regarding the publication of this paper.</p></sec><sec id="s10"><title>Cite this paper</title><p>Farhina, M. (2022) The Case Report on the Effectiveness of Infrared Light on Acid Burn Victim. Case Reports in Clinical Medicine, 11, 527-533. https://doi.org/10.4236/crcm.2022.1112071</p></sec></body><back><ref-list><title>References</title><ref id="scirp.122046-ref1"><label>1</label><mixed-citation publication-type="other" xlink:type="simple">Miccio, J., Parikh, S., Marinaro, X., Prasad, A., McClain, S., Singer, A.J. and Clark, R.A. (2016) Forward-Looking Infrared Imaging Predicts Ultimate Burn Depth in a Porcine Vertical Injury Progression Model. Burns, 42, 397-404. https://doi.org/10.1016/j.burns.2015.07.006</mixed-citation></ref><ref id="scirp.122046-ref2"><label>2</label><mixed-citation publication-type="other" xlink:type="simple">Karkada, G., Maiya, G.A., Houreld, N.N., Arany, P., Rao, K.G.M., Adiga, S., Kamath, S.U. and Shetty, S. (2020) Effect of Photobiomodulation Therapy on Inflammatory Cytokines in Healing Dynamics of Diabetic Wounds: A Systematic Review of Preclinical Studies. Archives of Physiology and Biochemistry, 1-8. https://doi.org/10.1080/13813455.2020.1861025</mixed-citation></ref><ref id="scirp.122046-ref3"><label>3</label><mixed-citation publication-type="other" xlink:type="simple">Dodd, E.M., Winter, M.A., Hordinsky, M.K., Sadick, N.S. and Farah, R.S. (2017) Photobiomodulation Therapy for Androgenetic Alopecia: A Clinician’s Guide to Homeuse Devices Cleared by the Federal Drug Administration. Journal of Cosmetic and Laser Therapy, 20, 159-167. https://doi.org/10.1080/14764172.2017.1383613</mixed-citation></ref><ref id="scirp.122046-ref4"><label>4</label><mixed-citation publication-type="other" xlink:type="simple">Yu, S.Y., Chiu, J.H., Yang, S.D., Hsu, Y.C., Lui, W.Y. and Wu, C.W. (2006) Biological Effect of Far-Infrared Therapy on Increasing Skin Microcirculation in Rats. Photodermatology, Photoimmunology &amp; Photomedicine, 22, 78-86. https://doi.org/10.1111/j.1600-0781.2006.00208.x</mixed-citation></ref><ref id="scirp.122046-ref5"><label>5</label><mixed-citation publication-type="other" xlink:type="simple">Mujeeb, A. and Kamal, A. (2018) Interpersonal Relationships, Psychological Effects, and Coping Strategies among Acid Burn Female Victims. Pakistan Journal of Psychological Research, 575-590.</mixed-citation></ref><ref id="scirp.122046-ref6"><label>6</label><mixed-citation publication-type="other" xlink:type="simple">Kuzin, M.I., Sologub, V.K., Vassermann, D. and Lavrov, V.A. (1985) Treatment of Burns with Infrared Rays in Patient Isolators. Vestnik Khirurgii Imeni II Grekova, 134, 74-79.</mixed-citation></ref><ref id="scirp.122046-ref7"><label>7</label><mixed-citation publication-type="other" xlink:type="simple">Aguida, B., Pooam, M., Ahmad, M. and Jourdan, N. (2021) Infrared Light Therapy Relieves TLR-4 Dependent Hyper-Inflammation of the Type Induced by COVID-19. Communicative &amp; Integrative Biology, 14, 200-211. https://doi.org/10.1080/19420889.2021.1965718</mixed-citation></ref><ref id="scirp.122046-ref8"><label>8</label><mixed-citation publication-type="other" xlink:type="simple">Gibson, W., Wand, B.M., Meads, C., Catley, M.J. and O’Connell, N.E. (2019) Transcutaneous Electrical Nerve Stimulation (TENS) for Chronic Pain—An Overview of Cochrane Reviews. Cochrane Database of Systematic Reviews, 4. https://doi.org/10.1002/14651858.CD011890.pub3</mixed-citation></ref><ref id="scirp.122046-ref9"><label>9</label><mixed-citation publication-type="other" xlink:type="simple">Nicolaou, V., Stasinopoulos, D. and Lamnisos, D. (2020) The Effectiveness of Polarized Light in Musculoskeletal, Skin Problems and Burns. American Journal of Biomedical Science &amp; Research, 10. https://doi.org/10.34297/AJBSR.2020.10.001492</mixed-citation></ref><ref id="scirp.122046-ref10"><label>10</label><mixed-citation publication-type="other" xlink:type="simple">Hamblin, M.R. and Demidova, T.N. (2006) Mechanisms of Low-Level Light Therapy. SPIE, 6140, Article ID: 614001. https://doi.org/10.1117/12.646294</mixed-citation></ref><ref id="scirp.122046-ref11"><label>11</label><mixed-citation publication-type="other" xlink:type="simple">Tsagkaris, C., Papazoglou, A.S., Eleftheriades, A., Tsakopoulos, S., Alexiou, A., G&amp;#259;man, M.A. and Moysidis, D.V. (2022) Infrared Radiation in the Management of Musculoskeletal Conditions and Chronic Pain: A Systematic Review. European Journal of Investigation in Health, Psychology and Education, 12, 334-343. https://doi.org/10.3390/ejihpe12030024</mixed-citation></ref></ref-list></back></article>