<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article  PUBLIC "-//NLM//DTD Journal Publishing DTD v3.0 20080202//EN" "http://dtd.nlm.nih.gov/publishing/3.0/journalpublishing3.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="3.0" xml:lang="en" article-type="research article"><front><journal-meta><journal-id journal-id-type="publisher-id">JBM</journal-id><journal-title-group><journal-title>Journal of Biosciences and Medicines</journal-title></journal-title-group><issn pub-type="epub">2327-5081</issn><publisher><publisher-name>Scientific Research Publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.4236/jbm.2022.104021</article-id><article-id pub-id-type="publisher-id">JBM-116701</article-id><article-categories><subj-group subj-group-type="heading"><subject>Articles</subject></subj-group><subj-group subj-group-type="Discipline-v2"><subject>Biomedical&amp;Life Sciences</subject></subj-group></article-categories><title-group><article-title>
 
 
  An Analysis of the Maximum Lifespan in the World and Japan
 
</article-title></title-group><contrib-group><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Fumio</surname><given-names>Maruyama</given-names></name><xref ref-type="aff" rid="aff1"><sub>1</sub></xref><xref ref-type="corresp" rid="cor1"><sup>*</sup></xref></contrib></contrib-group><aff id="aff1"><label>1</label><addr-line>Department of Sports and Health Science, Matsumoto University, Matsumoto, Japan</addr-line></aff><pub-date pub-type="epub"><day>30</day><month>03</month><year>2022</year></pub-date><volume>10</volume><issue>04</issue><fpage>254</fpage><lpage>262</lpage><history><date date-type="received"><day>21,</day>	<month>March</month>	<year>2022</year></date><date date-type="rev-recd"><day>19,</day>	<month>April</month>	<year>2022</year>	</date><date date-type="accepted"><day>22,</day>	<month>April</month>	<year>2022</year></date></history><permissions><copyright-statement>&#169; Copyright  2014 by authors and Scientific Research Publishing Inc. </copyright-statement><copyright-year>2014</copyright-year><license><license-p>This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/</license-p></license></permissions><abstract><p>
 
 
  Extreme value theory provides methods to analyze the most extreme parts of data. We used the generalized extreme value (GEV) distribution to predict the human lifespan in the world and Japan. The diagnostic plots, which assessed the accuracy of the GEV model, were fitted to the human lifespan, validating the model. The human lifespan in the world and Japan had shape parameters of ?0.1623 and ?0.2949 and had an upper limit. The calculated upper limit in the world was 128.7 years. The world’s oldest record holder, Jeanne Calment’s age of 122.45 years, was close to the 260-year return level and was far from the calculated upper limit. The calculated upper limit in Japan was 120.4 years. Japan’s oldest record holder, Kane Tanaka’s age of 119 years in 2022, was the 500-year return level and was close to the upper limit. In the world, achieving the calculated limit was difficult, but the human lifespan will soon reach the upper limit in Japan. 
 
</p></abstract><kwd-group><kwd>Human Lifespan</kwd><kwd> Extreme Value Theory</kwd><kwd> GEV Model</kwd></kwd-group></article-meta></front><body><sec id="s1"><title>1. Introduction</title><p>Both for and against a limit on the human lifespan were argued [<xref ref-type="bibr" rid="scirp.116701-ref1">1</xref>]. For humans, the maximum reported age at death is generally set at 122.45 years, the age at death of Jeanne Calment (France) in 1997. An estimation method for maximum human lifespan was developed and about 126 years was obtained from periodic life tables for Swedish females between 1950 and 2005. The age at death of the world’s oldest person has not increased since the 1990s, and the maximum lifespan is fixed and subject to natural constraints [<xref ref-type="bibr" rid="scirp.116701-ref2">2</xref>]. In western countries and Japan and after age 110, the risk of dying is constant and is about 47% per year. Human life is unlimited, and anyone will live longer than 128 years in western countries and Japan [<xref ref-type="bibr" rid="scirp.116701-ref3">3</xref>]. Our study contributes to this discussion from a statistical point of view and predicts the human lifespan in the world and Japan using the extreme value theory (EVT).</p><p>EVT has emerged as one of the most important statistical disciplines in applied science. Extreme value techniques are also widely used in other disciplines, such as financial market risk assessment and telecommunications traffic prediction [<xref ref-type="bibr" rid="scirp.116701-ref4">4</xref>]. EVT deals with statistical problems concerning the far tail of the probability distribution and is unique as a statistical tool since it develops models and techniques to describe the unusual event rather than the usual. Using EVT, the theoretical distribution and its population parameter that the maximum value follows are estimated from long-term observation data. Additionally, the maximum or large value that occurs once every period can be predicted based on the calculated results. Statistical approaches focused on extreme values have shown promising results in forecasting unusual events in earth science [<xref ref-type="bibr" rid="scirp.116701-ref5">5</xref>] [<xref ref-type="bibr" rid="scirp.116701-ref6">6</xref>], medicine [<xref ref-type="bibr" rid="scirp.116701-ref7">7</xref>] [<xref ref-type="bibr" rid="scirp.116701-ref8">8</xref>], finance [<xref ref-type="bibr" rid="scirp.116701-ref9">9</xref>], and sports [<xref ref-type="bibr" rid="scirp.116701-ref10">10</xref>].</p><p>In our study, we predict the human lifespan in the world and Japan using the extreme value theory.</p></sec><sec id="s2"><title>2. Data and Method of Analysis</title><sec id="s2_1"><title>2.1. Data</title><p>We used the human lifespan in the world and Japan from 1953 to 2018 [<xref ref-type="bibr" rid="scirp.116701-ref11">11</xref>] as shown in <xref ref-type="fig" rid="fig1">Figure 1</xref>.</p></sec><sec id="s2_2"><title>2.2. Method</title><p>The extreme value theory concerns the phenomena of extreme data. We used the block maxima method. A method for modeling the extremes of a stationary time series is block maxima, in which consecutive observations are grouped into non-overlapping blocks of length n, generating a series of m block maxima, Mn, 1, …, Mn, m, to which the Generalized Extreme Value (GEV) distribution can be fitted for some large value of n. The usual approach considers blocks of a given time length, thus yielding maxima at regular intervals [<xref ref-type="bibr" rid="scirp.116701-ref4">4</xref>]. Here a block</p><p>was considered as a year, i.e., annual maxima values were used. Although the block maxima method is suitable for analyzing maximum value data, it has the disadvantage of being easily affected by one realization value and having a large variance of the estimator.</p><p>When data are taken to be the maxima (or minima) over certain blocks of time (such as annual maximum precipitation), it is appropriate to use the GEV distribution:</p><p>G ( z ) = { exp { − [ 1 + ξ ( z − μ σ ) ] − 1 / ξ } , ξ ≠ 0 , exp { − exp [ − ( z − μ σ ) ] } , ξ = 0 , (1)</p><p>where z are extreme values from blocks, μ a location parameter, σ a scale parameter, and ξ a shape parameter. G(z) is defined for all z such that (1 + ξ(z − μ)/σ) &gt; 0 for ξ ≠ 0, and all z for ξ = 0. Three families of GEV distributions are defined depending on the value of ξ. We get the Fr&#233;chet distribution with a heavy tail for ξ &gt; 0, the Gumbel distribution with a lighter tail for ξ = 0, and the Weibull distribution with a finite tail for ξ &lt; 0.</p><p>If a GEV distribution is fitted to observations, it becomes possible to estimate the probability of an event that has not yet been observed. Estimates of extreme quantiles of the annual maximum distribution are obtained by inverting Equation (1):</p><p>z p = { μ − σ ξ [ 1 − { − log ( 1 − p ) } − ξ ] , ξ ≠ 0 , μ − σ log { − log ( 1 − p ) } , ξ = 0 , (2)</p><p>where G(z<sub>p</sub>) = 1 − p. z<sub>p</sub> is the return level associated with the return period 1/p, since z<sub>p</sub> is expected to be exceeded on average once every 1/p year with a reasonable degree of accuracy. More accurately, z<sub>p</sub> is exceeded by the annual maximum in any particular year with probability p [<xref ref-type="bibr" rid="scirp.116701-ref4">4</xref>].</p><p>Modeling was performed using the evd package in R for the GEV calculations. We also tried a non-stationary model in the GEV, but it did not work.</p></sec></sec><sec id="s3"><title>3. Results</title><sec id="s3_1"><title>3.1. Human Lifespan in the World</title><p>The human lifespan in the world from 1953 to 2018 is shown in <xref ref-type="fig" rid="fig1">Figure 1</xref>. Estimates of the GEV parameters, which were the results of the GEV modeling on the human lifespan in the world using the block maxima method, are shown in <xref ref-type="table" rid="table1">Table 1</xref>. The GEV parameters were estimated using the maximum likelihood estimation (MLE). The model has three parameters: location parameter, μ; scale parameter, σ; and shape parameter, ξ. Because ξ was −0.1623 with a 95% confidence interval, CI, (−0.3298, 0.005280), the human lifespan in the world has a finite upper limit.</p><p>Estimates of the maximum return levels for the return periods of 10, 20, 50, 100, and 500 years along with their respective 95% CI are shown in <xref ref-type="table" rid="table2">Table 2</xref>. We estimated the 10-year return level to be 118.0 years, with a 95% CI (116.7, 119.3). We estimated the 100-year return level to be 121.4 years, with a 95% CI (118.9, 123.9). We explain it differently, so it means that there is approximately a 1% chance (1/100) each year that the human lifespan will exceed 121.4 years. There is approximately a 10% chance (1/10) each year that the human lifespan will exceed 118 years.</p><p>The diagnostic plots for assessing the accuracy of the GEV model fitted to the human lifespan in the world are shown in <xref ref-type="fig" rid="fig2">Figure 2</xref>. Straight lines and curves in the solid lines represent estimated functions. Each point plot and short-dashed line are a realization value. The points on both sides represent the 95% CI. Probability and quantile plots show the validity of the proposed model: each set</p><table-wrap id="table1" ><label><xref ref-type="table" rid="table1">Table 1</xref></label><caption><title> GEV parameter estimates in the human lifespan in the world</title></caption><table><tbody><thead><tr><th align="center" valign="middle" ></th><th align="center" valign="middle" >μ</th><th align="center" valign="middle" >σ</th><th align="center" valign="middle" >ξ</th></tr></thead><tr><td align="center" valign="middle" >Parameter estimate</td><td align="center" valign="middle" >113.3</td><td align="center" valign="middle" >2.504</td><td align="center" valign="middle" >–0.1623</td></tr><tr><td align="center" valign="middle" >Standard error</td><td align="center" valign="middle" >0.4292</td><td align="center" valign="middle" >0.2964</td><td align="center" valign="middle" >0.08698</td></tr><tr><td align="center" valign="middle" >95% CI</td><td align="center" valign="middle" >(112.4, 114.1)</td><td align="center" valign="middle" >(1.923, 3.084)</td><td align="center" valign="middle" >(−0.3298, 0.005280)</td></tr></tbody></table></table-wrap><table-wrap id="table2" ><label><xref ref-type="table" rid="table2">Table 2</xref></label><caption><title> GEV return level estimates in the human lifespan in the world</title></caption><table><tbody><thead><tr><th align="center" valign="middle" >Return period (years)</th><th align="center" valign="middle" >10</th><th align="center" valign="middle" >20</th><th align="center" valign="middle" >50</th><th align="center" valign="middle" >100</th><th align="center" valign="middle" >500</th></tr></thead><tr><td align="center" valign="middle" >Return level (years)</td><td align="center" valign="middle" >118.0</td><td align="center" valign="middle" >119.2</td><td align="center" valign="middle" >120.5</td><td align="center" valign="middle" >121.4</td><td align="center" valign="middle" >123.1</td></tr><tr><td align="center" valign="middle" >Standard error</td><td align="center" valign="middle" >0.6483</td><td align="center" valign="middle" >0.7894</td><td align="center" valign="middle" >1.046</td><td align="center" valign="middle" >1.283</td><td align="center" valign="middle" >1.917</td></tr><tr><td align="center" valign="middle" >95% CI</td><td align="center" valign="middle" >(116.7, 119.3)</td><td align="center" valign="middle" >(117.6, 120.7)</td><td align="center" valign="middle" >(118.5, 122.6)</td><td align="center" valign="middle" >(118.9, 123.9)</td><td align="center" valign="middle" >(119.3, 126.8)</td></tr></tbody></table></table-wrap><p>of points follows a near-linear behavior. The corresponding density estimate is consistent with the data. In the return level curve, the estimated curve is nonlinear with a downward convex shape due to the negative ξ. Consequently, all diagnostic plots supported the fitted GEV model.</p></sec><sec id="s3_2"><title>3.2. Human Lifespan in Japan</title><p>The human lifespan in Japan from 1953 to 2018 is shown in <xref ref-type="fig" rid="fig1">Figure 1</xref>. Estimates of the GEV parameter, which were the results of the GEV modeling on the human lifespan in Japan using the block maxima method, are shown in <xref ref-type="table" rid="table3">Table 3</xref>. Because ξ was −0.2949 with a 95% CI (−0.6350, 0.04516), the human lifespan in the world has a finite upper limit.</p><p>Estimates of the maximum return levels for the return periods of 10, 20, 50, 100, and 500 years along with their respective 95% CI are shown in <xref ref-type="table" rid="table4">Table 4</xref>. We estimated the 10-year return level to be 115.9 years, with a 95% CI (114.7, 117.0). We estimated the 100-year return level to be 118.1 years, with a 95% CI (115.6, 120.7). Another way to interpret the plot is to say that there is approximately a 1% chance (1/100) each year that the human lifespan will exceed 118.1 years. There is approximately a 10% chance (1/10) each year that the human lifespan will exceed 115.9 years.</p><p>The diagnostic plots for assessing the accuracy of the GEV model fitted to the human lifespan in Japan are shown in <xref ref-type="fig" rid="fig3">Figure 3</xref>. In the return level curve, the estimated curve is nonlinear with a downward convex shape due to the negative ξ. All diagnostic plots supported the fitted GEV model.</p></sec></sec><sec id="s4"><title>4. Discussion</title><p>The human lifespan in the world and Japan from 1953 to 2018 is shown in <xref ref-type="fig" rid="fig1">Figure 1</xref>. The two tendencies are similar, but that in the world is more variable. The human lifespan in the world and Japan had shape parameters, ξ, of −0.1623 with a 95% CI (−0.3298, 0.005280) and −0.2949 with a 95% CI (−0.6350, 0.04516). Since ξ was negative, it had an upper limit.</p><p>The return levels at each return period for the human lifespan in the world and Japan are shown in <xref ref-type="fig" rid="fig4">Figure 4</xref>. In the case of ξ &lt; 0, the plots deviated from the straight line and were convex upward.</p><p>The return levels at each return period for the human lifespan in the world and Japan in a log-log plot are shown in <xref ref-type="fig" rid="fig5">Figure 5</xref>. Approximately straight lines are also shown. <xref ref-type="table" rid="table5">Table 5</xref> shows the results when the approximate straight line is y = bx<sup>a</sup>. Both cases were well approximated to the straight lines, following a power</p><table-wrap id="table3" ><label><xref ref-type="table" rid="table3">Table 3</xref></label><caption><title> GEV parameter estimates in the human lifespan in Japan</title></caption><table><tbody><thead><tr><th align="center" valign="middle" ></th><th align="center" valign="middle" >μ</th><th align="center" valign="middle" >σ</th><th align="center" valign="middle" >ξ</th></tr></thead><tr><td align="center" valign="middle" >Parameter estimate</td><td align="center" valign="middle" >111.6</td><td align="center" valign="middle" >2.576</td><td align="center" valign="middle" >–0.2949</td></tr><tr><td align="center" valign="middle" >Standard error</td><td align="center" valign="middle" >0.5310</td><td align="center" valign="middle" >0.4090</td><td align="center" valign="middle" >0.1735</td></tr><tr><td align="center" valign="middle" >95% CI</td><td align="center" valign="middle" >(110.6, 112.7)</td><td align="center" valign="middle" >(1.774, 3.377)</td><td align="center" valign="middle" >(−0.6350, 0.04516)</td></tr></tbody></table></table-wrap><table-wrap id="table4" ><label><xref ref-type="table" rid="table4">Table 4</xref></label><caption><title> GEV return level estimates in the human lifespan in Japan</title></caption><table><tbody><thead><tr><th align="center" valign="middle" >Return period (years)</th><th align="center" valign="middle" >10</th><th align="center" valign="middle" >20</th><th align="center" valign="middle" >50</th><th align="center" valign="middle" >100</th><th align="center" valign="middle" >500</th></tr></thead><tr><td align="center" valign="middle" >Return level (years)</td><td align="center" valign="middle" >115.9</td><td align="center" valign="middle" >116.7</td><td align="center" valign="middle" >117.6</td><td align="center" valign="middle" >118.1</td><td align="center" valign="middle" >119.0</td></tr><tr><td align="center" valign="middle" >Standard error</td><td align="center" valign="middle" >0.5771</td><td align="center" valign="middle" >0.7162</td><td align="center" valign="middle" >1.030</td><td align="center" valign="middle" >1.307</td><td align="center" valign="middle" >1.949</td></tr><tr><td align="center" valign="middle" >95% CI</td><td align="center" valign="middle" >(114.7, 117.0)</td><td align="center" valign="middle" >(115.3, 118.1)</td><td align="center" valign="middle" >(115.6, 119.6)</td><td align="center" valign="middle" >(115.6, 120.7)</td><td align="center" valign="middle" >(115.2, 122.8)</td></tr></tbody></table></table-wrap><table-wrap id="table5" ><label><xref ref-type="table" rid="table5">Table 5</xref></label><caption><title> The results when the approximate straight line is y = bx<sup>a</sup> in the human lifespan in the world and Japan. The correlation coefficient is indicated by r</title></caption><table><tbody><thead><tr><th align="center" valign="middle" ></th><th align="center" valign="middle" >World</th><th align="center" valign="middle" >Japan</th></tr></thead><tr><td align="center" valign="middle" >a</td><td align="center" valign="middle" >1.014 &#215; 10<sup>−2</sup></td><td align="center" valign="middle" >6.102 &#215; 10<sup>−3</sup></td></tr><tr><td align="center" valign="middle" >b</td><td align="center" valign="middle" >115.6</td><td align="center" valign="middle" >114.5</td></tr><tr><td align="center" valign="middle" >r</td><td align="center" valign="middle" >0.9935</td><td align="center" valign="middle" >0.9817</td></tr></tbody></table></table-wrap><p>law. A power low, known as a scaling law, is a relation of the type y = bx<sup>a</sup>, where y and x are variables of interest, a is called the power exponent, and b is a constant. This indicates a correlation between the return level and the return period. The inclination of the world (1.014 &#215; 10<sup>−2</sup>) is larger than that of Japan (6.102 &#215; 10<sup>−3</sup>). The human lifespan in the world will grow more in the future.</p><p>The calculated upper limit in the world was 128.7 years with a 95% CI (114.2, 143.2). The world’s oldest record holder, Jeanne Calment’s age of 122.45 years, was close to the 260-year return level and was far from the calculated upper limit. Based on a tendency for survival probability to be maximized in modern human survival curves, they developed an estimation method for maximum human lifespan and obtained about 126 years for Swedish females for 1950-2005 [<xref ref-type="bibr" rid="scirp.116701-ref1">1</xref>].</p><p>The calculated upper limit in Japan was 120.4 years with a 95% CI (112.5, 128.3). Japan’s oldest record holder, Kane Tanaka’s age of 119 years in 2022, was the 500-year return level and was close to the upper limit. Hence, in the world, achieving the calculated limit was difficult. However, in Japan, the human lifespan will soon reach the upper limit.</p></sec><sec id="s5"><title>5. Conclusions</title><p>Extreme value theory can provide methods to analyze the most extreme parts of data. We used the generalized extreme value (GEV) distribution to predict the human lifespan in the world and Japan. The results are summarized as follows:</p><p>1) The diagnostic plots, which assessed the accuracy of the GEV model, were fitted to the human lifespan, validating the model.</p><p>2) The human lifespan in the world and Japan had shape parameters of −0.1623 and −0.2949 and had an upper limit.</p><p>3) The calculated upper limit in the world was 128.7 years. The world’s oldest record holder, Jeanne Calment’s age of 122.45 years, was close to the 260-year return level and was far from the calculated upper limit.</p><p>4) The calculated upper limit in Japan was 120.4 years. Japan’s oldest record holder, Kane Tanaka’s age of 119 years in 2022, was the 500-year return level and was close to the upper limit. In the world, achieving the calculated limit was difficult, but the human lifespan will soon reach the upper limit in Japan.</p><p>5) The relationship between the return level of the human lifespan and the return period follows a power law.</p></sec><sec id="s6"><title>Conflicts of Interest</title><p>The author declares no conflicts of interest regarding the publication of this paper.</p></sec><sec id="s7"><title>Cite this paper</title><p>Maruyama, F. (2022) An Analysis of the Maximum Lifespan in the World and Japan. 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