<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article  PUBLIC "-//NLM//DTD Journal Publishing DTD v3.0 20080202//EN" "http://dtd.nlm.nih.gov/publishing/3.0/journalpublishing3.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="3.0" xml:lang="en" article-type="research article"><front><journal-meta><journal-id journal-id-type="publisher-id">OJAnes</journal-id><journal-title-group><journal-title>Open Journal of Anesthesiology</journal-title></journal-title-group><issn pub-type="epub">2164-5531</issn><publisher><publisher-name>Scientific Research Publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.4236/ojanes.2022.122007</article-id><article-id pub-id-type="publisher-id">OJAnes-115435</article-id><article-categories><subj-group subj-group-type="heading"><subject>Articles</subject></subj-group><subj-group subj-group-type="Discipline-v2"><subject>Medicine&amp;Healthcare</subject></subj-group></article-categories><title-group><article-title>
 
 
  State of Play of Anesthesia for Outpatient Medical and Surgical Procedures in the City of Kinshasa
 
</article-title></title-group><contrib-group><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Joseph</surname><given-names>Tsangu Phuati</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="corresp" rid="cor1"><sup>*</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Justin</surname><given-names>Mboloko Esimo</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Antoine</surname><given-names>Tshimpi Wola</given-names></name><xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Benjamin</surname><given-names>Longo-Mbenza</given-names></name><xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Medard</surname><given-names>Bulabula Isokuma</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Luc</surname><given-names>Mokassa Bakumobatane</given-names></name><xref ref-type="aff" rid="aff4"><sup>4</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Eric</surname><given-names>Amisi Bibonge</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Wilfrid</surname><given-names>Mbombo Dibwe</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Patrick</surname><given-names>Mukuna Miteo</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Patrick</surname><given-names>Kobo Utumpu</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Heritier</surname><given-names>Mawalala Malengele</given-names></name><xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Gibency</surname><given-names>Mfulani</given-names></name><xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Berthe</surname><given-names>Barhayiga Nsimire</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib></contrib-group><aff id="aff3"><addr-line>Department of Internal Medicine, University Clinics of Kinshasa, Kinshasa, DR Congo</addr-line></aff><aff id="aff1"><addr-line>Department of Anaesthesia and Intensive Care, University Clinics of Kinshasa, Kinshasa, DR Congo</addr-line></aff><aff id="aff4"><addr-line>Department of Surgery, University Clinics of Kinshasa, Kinshasa, DR Congo</addr-line></aff><aff id="aff2"><addr-line>Department of Gynaecology-Obstetrics, University Clinics of Kinshasa, Kinshasa, DR Congo</addr-line></aff><pub-date pub-type="epub"><day>23</day><month>02</month><year>2022</year></pub-date><volume>12</volume><issue>02</issue><fpage>77</fpage><lpage>90</lpage><history><date date-type="received"><day>9,</day>	<month>January</month>	<year>2022</year></date><date date-type="rev-recd"><day>21,</day>	<month>February</month>	<year>2022</year>	</date><date date-type="accepted"><day>24,</day>	<month>February</month>	<year>2022</year></date></history><permissions><copyright-statement>&#169; Copyright  2014 by authors and Scientific Research Publishing Inc. </copyright-statement><copyright-year>2014</copyright-year><license><license-p>This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/</license-p></license></permissions><abstract><p>
 
 
  <b>Context and Objective:</b> The practice of outpatient anaesthesia has many advantages over anesthesia with conventional hospitalisation, particularly in the reduction of post-operative complications and the faster resumption of activity, etc. No study has been carried out on this subject in our community; this study was carried out in order to come up with a concrete state of play when it comes to outpatient anesthesia for medical and surgical procedures in the city of Kinshasa. 
  <b>Methodology:</b> This was a cross-sectional study, which took place in seven hospitals in the city of Kinshasa from 1 November 2020 to 31 January 2021. The population consisted of all patients who received outpatient anesthesia and the included patients had signed an informed consent. The variables of the study were the general profile of patients, surgical procedures and indications, anesthetic data and patient evolution. Statistical analyses were performed with SPPS 21.0 with p &lt; 0.05 value. 
  <b>Results:</b> We collected data from 971 patients who had undergone anesthesia in the seven medical facilities in the city of Kinshasa. Among these patients, 394 had benefited from outpatient anesthesia, 
  i.e. a frequency of outpatient anesthesia estimated at 40.5%. Three hundred and ninety-four (394) patients were selected. They were 58.6% women and 41.4% men 
  i.e. a sex ratio M/F of 0.7. The mean age was 39.3 &#177; 18.7 years with the extremes of 1 and 82 years. Gastroscopy was the most performed (operative) procedure (21.6%). Patients were classified as ASA 1 in 75.1%, narcosis (80.7%) using propofol (80.2%) was the most used anesthetic technique and performed by a specialist doctor in Anesthesia in 65.5%. Suxamethonium was the most used curare in 13.2%. Fentanyl was the most used opioid in 14.5%. Bupivacaine (10.9%) was the most widely used local anesthetic. Eleven patients or 3.2% had complications and, 
  i.e. (0.8%) were hospitalized, class ASA II appeared to be a factor associated with complications. 
  <b>Conclusion:</b> Ambulatory anesthesia is a reality in the city of Kinshasa; however, it is still underdeveloped and mainly concerns explorations (gastroscopy, colonoscopy, laparoscopy…) and some minor procedures. This anesthesia mainly uses propofol and is done by the specialist doctor. A high-powered study and an evaluation of this practice in the light of international recommendations would be useful.
 
</p></abstract><kwd-group><kwd>Anesthesia</kwd><kwd> Medical and Surgical</kwd><kwd> Outpatient Procedures</kwd></kwd-group></article-meta></front><body><sec id="s1"><title>1. Introduction</title><p>Outpatient surgery is defined as surgical procedures and/or explorations programmed and performed under technical conditions that imperatively require the safety of an operating room, under anesthesia of variable mode and followed by post-operative monitoring allowing, without increased risk, the discharge of the patient on the same day. Outpatient surgery is therefore a scheduled surgery [<xref ref-type="bibr" rid="scirp.115435-ref1">1</xref>]. Outpatient management of medical and surgical procedures could be the standard of tomorrow, when 50% to 75% of these interventions will be performed according to this modality. An increasing number of interventions must already be performed on an ambulatory basis (knee arthroscopy, inguinal hernia cure, etc.) [<xref ref-type="bibr" rid="scirp.115435-ref2">2</xref>].</p><p>This method of care is considered to be beneficial in terms of the organization of the care system, the quality of care, patient satisfaction and it is a source of reduction in the cost of care. But it must be carried out under special organizational conditions allowing the patient to benefit from an intervention without additional risk and to be discharged the same day [<xref ref-type="bibr" rid="scirp.115435-ref3">3</xref>]. The duration of outpatient stay is less than 12 hours according the French medical literature and 24 hours according to the Anglo-Saxons [<xref ref-type="bibr" rid="scirp.115435-ref4">4</xref>].</p><p>In 2009, a large international survey concluded that it already concerned 83% of patients who underwent surgery in the USA, 74% in Denmark, 69% in Sweden, 53% in Great Britain, 53% in Holland, 50% in Norway, 49% in Portugal, 43% in Germany and 35% in France [<xref ref-type="bibr" rid="scirp.115435-ref5">5</xref>]. In 2017, a study conducted in France had found that it concerned 55.9% and projected to reach 70% in 2022 [<xref ref-type="bibr" rid="scirp.115435-ref6">6</xref>].</p><p>In Africa, studies on ambulatory anesthesia are scarce. Nevertheless, let us cite that of Khamouna in Morocco which reported the realities and prospects of this practice [<xref ref-type="bibr" rid="scirp.115435-ref7">7</xref>] and in the Democratic Republic of Congo (DRC), Luty AN et al. described the clinical profile of tonsillectomy indications in Lubumbashi and found that it was performed on an outpatient basis in 19% [<xref ref-type="bibr" rid="scirp.115435-ref8">8</xref>]. Ambulatory anesthesia is performed in the Democratic Republic of Congo but we do not have epidemiological data. Hence this study is carried out with the goal of making a state of play when it comes to anesthesia for outpatient medical and surgical procedures in the city of Kinshasa.</p></sec><sec id="s2"><title>2. Methods</title><sec id="s2_1"><title>2.1. Nature, Setting and Period of Study</title><p>This is a cross-sectional study that ran from November 01, 2020 to January 31, 2021 (i.e. three months). It took place in seven medical facilities in the city of Kinshasa all having an Anesthesia-Resuscitation department with the required equipment, ran by a permanent Anesthesiologist-Resuscitator;</p></sec><sec id="s2_2"><title>2.2. Population and Sampling</title><p>The population consisted of patients who underwent outpatient anesthesia in the selected centers. The study used an exhaustive sampling with consecutive recruitment of all patients who underwent surgery or exploration with outpatient anesthesia.</p></sec><sec id="s2_3"><title>2.3. Patient Selection</title><p>Were included in the study, all patients who had undergone surgery or exploration with outpatient anesthesia: seen in a pre-anesthetic consultation after a surgical consultation, had given their informed consent, and whose data collection form was correctly filled.</p><p>Any patient who underwent an anesthesia performed by the surgeon himself without the involvement of an anesthesiologist doctor, or a non-ambulatory anesthesia, was not included in the study.</p><p>Patients who did not give an informed consent and those whose data collection form did not contain all the variables of interest were excluded from the study.</p><p>The data processing was carried out in several stages: manual examination of the data collection form; typing; purification and encoding on Microsoft Excel 2013 software.</p></sec><sec id="s2_4"><title>2.4. Study Variables</title><p>Concerning the variables of the study, we established a data collection sheet (questionnaire) which allowed us to collect all the necessary information on the progress of the anesthetic management of the medico-surgical acts. Data obtained from different data collection sheets were analyzed. Among its variables we have.</p><p>We needed age, sex, estimated distance from home in terms of time, level of education as socio-demographic variables.</p><p>In the pre-operative period we were looking for: the pre-operative diagnosis, planned operative act and/or exploration, ASA class, prescription of analgesics, delivery of the document concerning the instructions, estimated duration of the operation, pre-anesthetic visit.</p><p>In the intraoperative period, we were looking for: the intraoperative diagnosis, procedure performed, qualification of the operator, PONV prevention, type of anesthesia, anesthetic drugs used, complications encountered, actual duration of the operation, administration of analgesics.</p><p>In the postoperative period, we had to make sure there was a telephone contact between the patient and the hospital team, the patient had an attendant, whether the patient had returned to the hospital, the discharge score assessed, if there was had thromboembolism prevention.</p></sec><sec id="s2_5"><title>2.5. Statistical Analyzes</title><p>Analysis was performed on SPSS software version. Pearson’s chi-square test or Ficher’s exact test was performed to compare the percentages. Student’s T test to compare means. The factors associated with the complications were seeked by logistic regression with the calculation of the odds ratio (OR) in order to determine the degree of risk. The p-value &lt;0.05 was defined as the threshold of significance.</p></sec><sec id="s2_6"><title>2.6. Ethical Considerations</title><p>This study was approved by the ethics committee of the School of Public Health of the Faculty of Medicine of the University of Kinshasa under the number: N˚ ESP/CE/127B/2020.</p></sec></sec><sec id="s3"><title>3. Results</title><p>We collected data from 971 patients who underwent anesthesia in seven medical facilities in the city of Kinshasa province. Among these patients, 394 had received outpatient anesthesia and were the subject of this study, while 577 did not meet our inclusion criteria because they were subject to conventional hospitalization. Hence the frequency of ambulatory anesthesia has been estimated at 40.5%.</p><sec id="s3_1"><title>3.1. Patient Profile (See <xref ref-type="table" rid="table1">Table 1</xref>)</title><p>Among the 394 patients registered, there were 231 women (58.6%) and 163 men (41.4%), i.e. a sex ratio M/F of 0.7 (163/231). The mean age was 39.3 &#177; 18.7 years with the age ranges of 1 and 82 years, and that of men 43.9 &#177; 20.5 years was higher than that of women (p &lt; 0.001). Most patients were between 21 and 30 years old, i.e. 26.4% of cases. In most cases medical cares were paid by companies, the distance from home to hospital was less than an hour in 89.8% and education level was high in 72.8%.</p><table-wrap id="table1" ><label><xref ref-type="table" rid="table1">Table 1</xref></label><caption><title> General profile of the study population</title></caption><table><tbody><thead><tr><th align="center" valign="middle"  rowspan="2"  >Variables</th><th align="center" valign="middle"  rowspan="2"  >All n = 394</th><th align="center" valign="middle"  colspan="2"  >Sex</th><th align="center" valign="middle"  rowspan="2"  >P</th></tr></thead><tr><td align="center" valign="middle" >Men n = 163</td><td align="center" valign="middle" >Women n = 231</td></tr><tr><td align="center" valign="middle" >Age, year X &#177; ET Me (EIQ) Age groups ≤20 ans 21 &#224; 30 ans 31 &#224; 40 ans 41 &#224; 50 ans 51 &#224; 60 ans &gt;60 ans Financing of care Enterprise Private/Personal Distance from home &lt;1 hour &gt;1 hour Level of education Illiterate Primary Secondary Superior or university</td><td align="center" valign="middle" >39.3 &#177; 18.7 37 (26 - 56) 49 (12.4) 104 (26.4) 63 (15.9) 61 (15.5) 49 (12.4) 68 (17.3) 257 (65.2) 137 (34.8) 354 (89.8) 40 (10.2) 7 (1.8) 27 (7) 66 (17.1) 287 (72.8)</td><td align="center" valign="middle" >43.9 &#177; 20.5 26 (53.1) 12 (11.5) 25 (39.7) 32 (52.5) 27 (55.1) 41 (60.3) 111 (43.2) 52 (37.9) 147 (41.5) 16 (40) 5 (71.4) 14 (51.9) 18 (27.3) 120 (41.8)</td><td align="center" valign="middle" >36.2 &#177; 16.5 23 (46.9) 92 (88.5) 38 (60.3) 29 (47.5) 22 (44.9) 27 (39.7) 146 (56.8) 85 (62) 207 (58.5) 24 (60) 2 (28.6) 13 (48.1) 48 (72.7) 167 (58.2)</td><td align="center" valign="middle" >&lt;0.001 0.655 0.853 0.001</td></tr></tbody></table></table-wrap><p>The data are expressed as a mean &#177; standard deviation, absolute frequency (n) and percentage (%).</p></sec><sec id="s3_2"><title>3.2. Indications for Surgery (See <xref ref-type="table" rid="table2">Table 2</xref>)</title><p>Explorations were the predominant indication (55.1%) and more concerned men (p &lt; 0.001), after which were the following: the OB-GYN indications in 24.1%, ENT in 8.4%, urological in 4.2%, trauma (4.1%) and general surgery 2.5%.</p></sec><sec id="s3_3"><title>3.3. Operative Procedures (See <xref ref-type="table" rid="table3">Table 3</xref>)</title><p>Gastroscopy was the most performed exploration (21.6%) followed by laparoscopy at 12.7%. Endo-uterine aspiration was the most OB-GYN procedure at 14.9% followed by lumpectomy of the breast at 6.6%. Among ENT cases, adenoidectomy and tonsillectomy were performed in 7.6% and 0.5%, respectively.</p></sec><sec id="s3_4"><title>3.4. Anesthetic Data (See <xref ref-type="table" rid="table4">Table 4</xref>)</title><p>Almost all of the patients (75.1%) were classified ASA 1 with significantly higher proportions in women than in men (65.5% versus 34.5% p &lt; 0.001). There were no written instructions in 99.7%, or written pain medication prescriptions in 97.9%. The average procedure duration was one hour and in most cases the procedure lasted about less than an hour and a half, or 98.2% of cases. Written forrm of PAC were found in 57.8%, those of pre-anesthetic fasting in 96.7% of patients, with no significant difference between the two groups (p &gt; 0.05). The anesthetic techniques were: propofol narcosis (80.7%), general anesthesia with intubation (13.2%) and spinal anesthesia (4.8%). The anesthesiologist was senior resident doctor in 65.4% and the operator was attending doctor in 95.9%.</p><table-wrap id="table2" ><label><xref ref-type="table" rid="table2">Table 2</xref></label><caption><title> Surgical indications</title></caption><table><tbody><thead><tr><th align="center" valign="middle"  rowspan="2"  >Variables</th><th align="center" valign="middle"  rowspan="2"  >All n = 394</th><th align="center" valign="middle"  colspan="2"  >Sex</th><th align="center" valign="middle"  rowspan="2"  >P</th></tr></thead><tr><td align="center" valign="middle" >Men n = 163</td><td align="center" valign="middle" >Women n = 231</td></tr><tr><td align="center" valign="middle" >Explorations OB-GYN pathologies Pregnancy stopped Breast adenofibroma Incomplete abortion Cervical gaping Condylomata Placenta retention Urological pathologies Stenosis Kidney stones Hernia Vaginal hydrocele Orthopaedic pathologies Fracture Dislocation Pathologies ORL Adenoids Chronic tonsillitis Foreign body ear Enchondrome temporal General surgery Abscess Lipome Circonsion Other</td><td align="center" valign="middle" >217 (55.1) 95 (24.1) 31 (7.8) 26 (6.6) 20 (5.1) 10 (2.5) 5 (1.3) 3 (0.8) 16 (4.1) 7 (1.8) 5 (1.3) 3 (0.8) 1 (0.3) 16 (4.1) 13 (3.3) 3 (0.8) 34 (8.6) 30 (7.6) 2 (0.5) 1 (0.3) 1 (0.3) 10 (2.5) 4 (1) 2 (0.5) 4 (1) 6 (1.5)</td><td align="center" valign="middle" >114 (52.5) 0 0 0 0 0 0 7 (100) 5 (100) 1 (33.3) 1 (100) 11 (84.6) 1 (33.3) 11 (36.7) 2 (100) 0 0 0 2 (100) 4 (100) 5 (83.3)</td><td align="center" valign="middle" >103 (47.5) 31 (100) 26 (100) 20 (100) 10 (100) 5 (100) 3 (100) 0 0 2 (66.7) 0 2 (15,4) 2 (66.7) 19 (63.3) 0 1 (100) 1 (100) 4 (100) 0 0 1 (16.7)</td><td align="center" valign="middle" >&lt;0.001</td></tr></tbody></table></table-wrap><p>The data are expressed as a mean &#177; standard deviation, absolute frequency (n) and percentage (%).</p><table-wrap id="table3" ><label><xref ref-type="table" rid="table3">Table 3</xref></label><caption><title> Surgical procedures</title></caption><table><tbody><thead><tr><th align="center" valign="middle"  rowspan="2"  >Variables</th><th align="center" valign="middle"  rowspan="2"  >All n = 394</th><th align="center" valign="middle"  colspan="2"  >Sex</th><th align="center" valign="middle"  rowspan="2"  >P</th></tr></thead><tr><td align="center" valign="middle" >Men n = 163</td><td align="center" valign="middle" >Women n = 231</td></tr><tr><td align="center" valign="middle" >Explorations Gastroscopy Laparoscopy Gastro-colonoscopy Bronchoscopy Cystoscopy MRI and brain ct-scan Gyneco-obstetrics Uterine aspiration Tumorectomy Cerclage Cauterization Urological Dilatation Double J stent installation Orthopedic Reduction + restraint Simple discount Removal of materials ORL Adenoidectomy Amygdalectomy General surgery Circumcision Lipomectomy Other</td><td align="center" valign="middle" >85 (21.6) 50 (12.7) 43 (10.9) 10 (2.5) 10 (25) 8 (2) 59 (14.9) 26 (6.6) 10 (2.5) 7 (1.7) 7 (1.7) 5 (1.2) 8 (1.5) 8 (1.5) 5 (1.2) 30 (7.6) 2 (0.5) 4 (1) 2 (0.5) 15 (3.8)</td><td align="center" valign="middle" >39 (45.9) 0 21 (48.8) 6 (60) 10 (100) 7 (87.5) 0 0 0 0 7 (100) 5 (100) 3 (37.5) 4 (50) 3 (60) 18 (60) 1 (50) 4 (100) 2 (100) 12 (80)</td><td align="center" valign="middle" >46 (54.1) 50 (100) 22 (51.2) 4 (40) 0 1 (12.5) 59 (100) 26 (100) 10 (100) 7 (100) 0 0 5 (62.5) 4 (50) 2 (40) 12 (40) 1 (50) 0 0 3 (20)</td><td align="center" valign="middle" >&lt;0.001</td></tr></tbody></table></table-wrap><p>The data are expressed as a mean &#177; standard deviation, absolute frequency (n) and percentage (%).</p></sec><sec id="s3_5"><title>3.5. Data on Patient Progress (See <xref ref-type="table" rid="table5">Table 5</xref>)</title><p>Eleven patients (3.2%) presented complications (desaturation, hypotension, bradycardia, bradypnea). Prevention of postoperative nausea and vomiting was carried out in 17.5% of patients, 99.2% of patients were accompanied, 0.8% returned to hospital, there was no written record of the score assessment before discharge in 99% and length of stay was less than 12 hours in 66.4% and longer in 32.8%.</p><table-wrap id="table4" ><label><xref ref-type="table" rid="table4">Table 4</xref></label><caption><title> Anesthetic data from the study population</title></caption><table><tbody><thead><tr><th align="center" valign="middle"  rowspan="2"  >Variables</th><th align="center" valign="middle"  rowspan="2"  >All n = 394</th><th align="center" valign="middle"  colspan="2"  >Sex</th><th align="center" valign="middle"  rowspan="2"  >P</th></tr></thead><tr><td align="center" valign="middle" >Male n = 163</td><td align="center" valign="middle" >Women n = 231</td></tr><tr><td align="center" valign="middle" >ASA Class 1 2 3 Analgesic prescription/PAC Yes No Instructions Yes Non Procedure duration X &#177; ET &lt;1h30' &gt;1h30' Pre-anesthetic fasting Yes No PAC No Yes Anaesthetist qualification senior Internal Anaesthetist Technician Operator Qualification senior Internal General practitionner Type of anesthesia General + Intubation Spinal Anesthesia Local anesthesia Narcosis (propofol) Block Combined</td><td align="center" valign="middle" >296 (75.1) 92 (23.4) 6 (1.5) 8 (2.1) 373 (97.9) 1 (0.3) 393 (99.7) 1&#177;0.1 387 (98.2) 7 (1.8) 381 (96.7) 13 (3.3) 166 (42.2) 227 (57.8) 258 (65.5) 135 (34) 1 (0.3) 374 (94.9) 5 (1.3) 15 (3.8) 52 (13.2) 19 (4.8) 2 (0.5) 318 (80.7) 2 (0.5) 1 (0.3)</td><td align="center" valign="middle" >102 (34.5) 59 (64.1) 2 (33.3) 3 (37.5) 152 (40.8) 0 163 (41.6) 160 (41.3) 3 (42.9) 161 (42.3) 2 (15.4) 74 (44.6) 88 (38.8) 107 (41.5) 55 (40.3) 1 (100) 158 (42.2) 0 5 (33.3) 20 (38.5) 13 (68.4) 0 130 (40.9) 0 0</td><td align="center" valign="middle" >194 (65.5) 33 (35.9) 4 (66.7) 5 (62.5) 221 (59.2) 1 (100) 229 (58.4) 227 (58.7) 4 (57.1) 220 (57.7) 11 (84.6) 92 (55.4) 139 (61.2) 151 (58.5) 80 (59.7) 0 216 (57.8) 5 (100) 10 (66.7) 32 (61.5) 6 (31.6) 2 (100) 188 (59.1) 2 (100) 1 (100)</td><td align="center" valign="middle" >&lt;0.001 0.853 0.399 0.692 0.106 0.248 0.407 0.257 0.105</td></tr></tbody></table></table-wrap><p>The data are expressed as a mean &#177; standard deviation, absolute frequency (n) and percentage (%).</p><table-wrap id="table5" ><label><xref ref-type="table" rid="table5">Table 5</xref></label><caption><title> Patient evolution data</title></caption><table><tbody><thead><tr><th align="center" valign="middle"  rowspan="2"  >Variables</th><th align="center" valign="middle"  rowspan="2"  >All n = 394</th><th align="center" valign="middle"  colspan="2"  >Sex</th><th align="center" valign="middle"  rowspan="2"  >P</th></tr></thead><tr><td align="center" valign="middle" >Men n = 163</td><td align="center" valign="middle" >Women n = 231</td></tr><tr><td align="center" valign="middle" >Complications None Present Desaturation Hypotension Bradycardia Bradypnea Prevention NVPO Yes Not Accompanying Present Absent Back to hospital Yes Not Discharging score CHUNG PADSS No evaluation Thromboembolic prev. Yes Not Length of stay X &#177; ET ≤12 Hours &gt;12 hours</td><td align="center" valign="middle" >381 (96.8) 13 (3.2) 6 (1.5) 3 (0.6) 2 (0.5) 2 (0.5) 69 (17.5) 325 (85.1) 391 (99.2) 3 (0.8) 3 (0.8) 391 (99.2) 1 (0.5) 3 (0.8) 390 (99) 2 (0.5) 392 (99.5) 11.9 &#177; 6.4 262 (66.4) 132 (32.6)</td><td align="center" valign="middle" >154 (40.4) 9 (69.3) 4 (60) 3 (100) 2 (100) 2 (100) 29 (42) 134 (41.2) 162 (41.4) 1 (33.3) 2 (66.7) 161 (41.2) 1 (100) 2 (66.7) 160 (41) 1 (50) 167 (42.6) 12.4 &#177; 6.6 103 (39.3) 60 (45.5)</td><td align="center" valign="middle" >227 (59.6) 4 (30.7) 2 (40) 0 0 0 40 (58) 191 (58.8) 229 (58.6) 2 (66.7) 1 (33.3) 230 (58.8) 0 1 (33.3) 230 (59) 1 (50) 225 (57.4) 11.7 &#177; 6.3 159 (60.7) 72 (54.5)</td><td align="center" valign="middle" >0.239 0.534 0.777 0.372 0.328 0.788 0.300</td></tr></tbody></table></table-wrap><p>The data are expressed as a mean &#177; standard deviation, absolute frequency (n) and percentage (%).</p></sec><sec id="s3_6"><title>3.6. Main Anesthetic Drugs Used (See <xref ref-type="table" rid="table6">Table 6</xref>)</title><p>Propofol was the most widely used narcotic (80.2%) followed by ketamine 6.3%. Halothane was used more than sevoflurane 4.3% and 1%, respectively (as halogen). Suxamethonium was the most used curare (13.2%) exceeding vecuronium (3.6%), rocuronium (0.8%) and atracurium (0.3%). Fentanyl was the most widely used opioid drug in 14.5%. Bupivacaine was the most used local anesthetic in 10.9%.</p></sec><sec id="s3_7"><title>3.7. Determinants of Complications (See <xref ref-type="table" rid="table7">Table 7</xref>)</title><p>In univariate analysis, the determinants of complications were, age over 37 years, ASA II class and narcosis. In multivariate analysis, the strength of association persisted only for ASA class 2 [ORa: 3.3 95% CI (1.1 - 9.7) p = 0.023].</p><table-wrap id="table6" ><label><xref ref-type="table" rid="table6">Table 6</xref></label><caption><title> Main anesthetic drugs used</title></caption><table><tbody><thead><tr><th align="center" valign="middle"  rowspan="2"  >Variables</th><th align="center" valign="middle"  rowspan="2"  >N n = 394</th><th align="center" valign="middle"  colspan="2"  >Sex</th><th align="center" valign="middle"  rowspan="2"  >P</th></tr></thead><tr><td align="center" valign="middle" >Men n = 163</td><td align="center" valign="middle" >Women n = 231</td></tr><tr><td align="center" valign="middle" >Narcotics Propofol Ketamine Midazolam Halogenic Halothane Sevoflurane Curares Suxamethonium V&#233;curonium Atracurium Rocuronium Analgesics Fentanyl Sufentanil Morphine Local anesthestic Bupivacaine Xylocaine</td><td align="center" valign="middle" >316 (80.2) 25 (6.3) 36 (9.1) 17 (4.3) 4 (1) 52 (13.2) 14 (3.6) 1 (0.3) 3 (0.8) 57 (14.5) 4 (1) 6 (1.5) 43 (10.9) 6 (1.5)</td><td align="center" valign="middle" >123 (38.9) 8 (32) 14 (38.9) 4 (23.5) 1 (25) 11 (21.2) 5 (35.7) 0 1 (33.3) 13 (22.8) 2 (50) 2 (33.3) 21 (48.8) 4 (66.7)</td><td align="center" valign="middle" >193 (61.1) 17 (68) 22 (61.1) 13 (76.5) 3 (75) 41 (78.8) 9 (64.3) 1 (100) 2 (66.7) 44 (77.2) 2 (50) 4 (66.7) 22 (51.2) 2 (33.3)</td><td align="center" valign="middle" >0.034</td></tr></tbody></table></table-wrap><p>Data are expressed as mean &#177; standard deviation, absolute frequency (n) and relative frequency (percent).</p><table-wrap id="table7" ><label><xref ref-type="table" rid="table7">Table 7</xref></label><caption><title> Determinants of complications during outpatient anesthesia</title></caption><table><tbody><thead><tr><th align="center" valign="middle"  rowspan="2"  >Determinants</th><th align="center" valign="middle"  colspan="2"  >Univariate analysis</th><th align="center" valign="middle"  colspan="2"  >Multivariate analysis</th></tr></thead><tr><td align="center" valign="middle" >P</td><td align="center" valign="middle" >OR (IC95%)</td><td align="center" valign="middle" >P</td><td align="center" valign="middle" >ORa (IC95%)</td></tr><tr><td align="center" valign="middle" >Sex Women Men Age ≤37 y &gt;37 y ASA Class 1 2 Type of anesthesia Others Narcosis</td><td align="center" valign="middle" >0.038 0.014 0.004 0.007</td><td align="center" valign="middle" >1 3.1 (0.9 - 10.2) 1 1.1 (1 - 1.1) 1 2.1 (1.2 - 3.1) 1 3.1 (1.1 - 9.7)</td><td align="center" valign="middle" >0.887 0.301 0.023 0.146</td><td align="center" valign="middle" >1 1.09 (0.3 - 3.7) 1 0.3 (0.03 - 2.1) 1 3.3 (1.1 - 9.7) 1 0.9 (0.02 - 2.7)</td></tr></tbody></table></table-wrap><p>Other procedures: lung biopsy, hysteroscopy, lipomectomy, rectoscopy, cystoscopy, double J probe placement, circumcision, herniorraphy, hysteroscopy, foreign body extraction.</p></sec></sec><sec id="s4"><title>4. Discussion</title><p>Our sample was 394 patients larger than that of Khamouna [<xref ref-type="bibr" rid="scirp.115435-ref7">7</xref>] in Morocco which had 100 patients in a single-center study. The frequency of ambulatory anesthesia in our series is 40.5%, lower than in the last French study that reported a frequency of 55.9% [<xref ref-type="bibr" rid="scirp.115435-ref6">6</xref>]. Note that our study concerned only a few medical facilities in the city of Kinshasa and the distribution of this practice is disparate.</p><p>Ambulatory anesthesia seems to be used much more in young women (58.6%). Patients under the age of 20 only represented 12.4%, while Khamouna [<xref ref-type="bibr" rid="scirp.115435-ref7">7</xref>] found that 68% were under 15 years old. The mean age was 39.3 &#177; 16.5 years. The youngest patient was one year old and the oldest was 82 years old, because apart from prematurity there are no age limits for outpatient anesthesia [<xref ref-type="bibr" rid="scirp.115435-ref9">9</xref>].</p><p>Graduate instruction level patients were in the majority in 59.2%, as it takes a certain level of understanding to understand and follow the instructions for this anesthesia. The majority of our patients (89.9%) took less than an hour to reach medical facilities as per SFAR recommendations [<xref ref-type="bibr" rid="scirp.115435-ref9">9</xref>].</p><p>Explorations represented 55.1% of the indications followed by OB-GYN procedures, unlike Khamouna [<xref ref-type="bibr" rid="scirp.115435-ref7">7</xref>] who noted a predominance of ENT indications in 38%. It seems that, in our community, the teams are still afraid of performing a lot of outpatient surgeries not only because of the level of understanding of the patients, but also of the traffic jams that can delay a fast return of the patient to the hospital in the event of complications.</p><p>Our study noted that 75.1% of the patients were classified ASA I. The ASA II and III patients represented 23.4% and 1.5% respectively. These results corroborate the formalized expert recommendations of the 2010 French Society of Resuscitation (SFAR) [<xref ref-type="bibr" rid="scirp.115435-ref9">9</xref>] which establish that ASA I, ASA II and ASA III (stable) patients are eligible for outpatient anesthetic treatment. Khamouna’s study [<xref ref-type="bibr" rid="scirp.115435-ref7">7</xref>] did not register ASA III patients because they were not included.</p><p>Written recommendations were given to only one patient out of the 394 (i.e. 0.3%), this is explained by the fact of our oral tradition probably, the operators in this modality of care were limited to verbal instructions while the 2010 formalized recommendations from the experts of the French Society and Resuscitation (SFAR) [<xref ref-type="bibr" rid="scirp.115435-ref9">9</xref>] of require the mandatory submission of an information document (instructions) after oral information. However, there is no such legislation in the Democratic Republic of the Congo.</p><p>In this study, the proportion of patients who benefited from the pre-anesthetic Consultation (PAC) was 57.8%, the patients who were not consulted by an anesthesiologist prior to the procedure were those who were assessed on the day of the procedure. This reality deviates from the 2010 formalized recommendations of the French Society of Resuscitation (SFAR) experts [<xref ref-type="bibr" rid="scirp.115435-ref9">9</xref>], which require patients to be consulted by an anesthesiologist at least 48 hours earlier to allow them to make necessary arrangements (on pre-operative fasting, on habits, explanations on the different anesthetic protocols…).</p><p>Pre-anesthetic fasting was effective in 96.7% of patients. Other authors such as Warner MA in 1999 [<xref ref-type="bibr" rid="scirp.115435-ref10">10</xref>] and Pandit SK in 2000 [<xref ref-type="bibr" rid="scirp.115435-ref11">11</xref>] as well as the recommendations of the ASA [<xref ref-type="bibr" rid="scirp.115435-ref10">10</xref>] [<xref ref-type="bibr" rid="scirp.115435-ref11">11</xref>] insist on this preoperative fast to avoid both inhalations and the disadvantages of prolonged fasting. The average duration of intervention was one hour and in most cases, the intervention lasted about one hour and thirty minutes, i.e. 98.2% of cases according to the 2010 formalized recommendations of SFAR experts [<xref ref-type="bibr" rid="scirp.115435-ref9">9</xref>].</p><p>Narcosis was the most widely used type of anesthesia (82.4%) because it is best suited to short lasting procedures. Propofol has been the most widely used narcotic because of its good kinetics as other authors had suggested [<xref ref-type="bibr" rid="scirp.115435-ref12">12</xref>] [<xref ref-type="bibr" rid="scirp.115435-ref13">13</xref>]. Suxamethonium was the most used curare in our study (13.2%). It is used to facilitate tracheal intubation but exposes the patient to postoperative myalgia related to fasciculation (in 5% to 10% of cases especially if the rise and ambulation are early, which is the rule in outpatient settings). In our study, it was used without this adverse effect. Although Lemmens [<xref ref-type="bibr" rid="scirp.115435-ref14">14</xref>] has established since 1998, that the morphinics to be preferred on an outpatient basis are remifentanil, alfentanil and sufentanil because of their rapid elimination, fentanyl was used in 14.5% in our series because of its availability on the market so morphinics less prone to residual effects are rare on the local market.</p><p>In this study, eleven patients had complications (3.2%): desaturation, hypotension, bradycardia and bradypnea. In a Matthew meta-analysis [<xref ref-type="bibr" rid="scirp.115435-ref12">12</xref>], the mean rates of airwayevents (partial or complete obstruction, apnea and hypoxia) and haemodynamic events (low blood pressure, arrhythmia, tachycardia, bradycardia) were 1.44%. Our complication rate exceeds Matthew’s because he had only worked on sedations.</p><p>Almost all patients were accompanied as recommended [<xref ref-type="bibr" rid="scirp.115435-ref9">9</xref>]. The majority of patients were almost not assessed before being discharged, only 3 patients out of the 394 i.e. 0.8% were assessed by the Chung score. An attitude that deviates from the principles of outpatient anesthetic care. As a matter of fact, it is the lack of a document proving this evaluation that is missing and not the consultation itself. The proportion of patients who benefited from thromboembolic prevention was 0.5%. Here we must qualify the fact that our series had no major interventions. But this is one of the advantages offered by this mode of care [<xref ref-type="bibr" rid="scirp.115435-ref15">15</xref>]. The average length of stay was 11.9 &#177; 6.4 hours and most patients had stayed more than 12 hours (67.3%), this result corroborates the conception of Anglo-Saxon countries on outpatient anesthetic care (&lt;24 hours) [<xref ref-type="bibr" rid="scirp.115435-ref4">4</xref>].<sup> </sup></p><p>In this study, only ASA II class [ORa: 3.3% CI 1.1 - 9.7) p = 0.023] appeared to be the determinant of complications. This result is different from Ansell’s observation in 1998 [<xref ref-type="bibr" rid="scirp.115435-ref16">16</xref>] who retrospectively assessed the outcome of patients following outpatient surgery. Among the 30,000 outpatients managed on an outpatient basis between 1998 and 2002, 3.3% were classified as ASA III. Compared with an ASA I or II control group, matched in age, sex, type and year of intervention, the incidence of postoperative complications was similar in both groups. Similarly, the percentage of unplanned hospitalization was comparable (2.9% and 1.9% for ASA III and ASA I or II patients respectively) [<xref ref-type="bibr" rid="scirp.115435-ref16">16</xref>]. However, the under-representation of ASA III patients in our study should be noted.</p><p>Limitations of the study:</p><p>- This study does not allow a direct comparison of the advantages (benefits) of ambulatory anesthesia to conventional hospitalization.</p><p>- The non-follow-up of patients who have benefited from ambulatory anesthesia after their discharge from hospital.</p></sec><sec id="s5"><title>5. Conclusions</title><p>Ambulatory anesthesia is a reality in the city of Kinshasa; however, it is still underdeveloped with different frequencies depending on the hospital.</p><p>Half of outpatient anesthesia is indicated for explorations (gastroscopy, colonoscopy, laparoscopy, etc.). But it is also worth noting some essentially minor interventions. Almost all patients are classified as ASA I and these procedures are most often performed by senior doctors. Propofol is the most widely used narcotic. Complications, although rare, are related to class ASA II.</p><p>There is clearly interest in broadening the indications to make it a priority axis for the development of surgery, anesthesia and a source of health savings, as in Western countries. An effort should also be made to comply with the recommendations of learned societies.</p></sec><sec id="s6"><title>Authors’ Contribution</title><p>- Tsangu Joseph designed, collected, interpreted, wrote the manuscript;</p><p>- Longo-Mbenza Benjamain coordinated the writing of the article;</p><p>- Mfulani Gibency carried out the statistical analyses;</p><p>- Mbombo Wilfrid and the others corrected the manuscript.</p></sec><sec id="s7"><title>Conflicts of Interest</title><p>The authors declare no conflicts of interest regarding the publication of this paper.</p></sec><sec id="s8"><title>Cite this paper</title><p>Tsangu Phuati, J., Mboloko Esimo, J., Tshimpi Wola, A., Longo-Mbenza, B., Bulabula Isokuma, M., Mokassa Bakumobatane, L., Amisi Bibonge, E., Mbombo Dibwe, W., Mukuna Miteo, P., Kobo Utumpu, P., Mawalala Malengele, H., Mfulani, G. and Barhayiga Nsimire, B. (2022) State of Play of Anesthesia for Outpatient Medical and Surgical Procedures in the City of Kinshasa. 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