Scoliosis is a complex musculoskeletal three-dimensional torsional deformity of the spine that includes [1]: -

a) Lateral curvature in the anterior-posterior plane with a Cobb angle measuring greater than 10 degrees,

b) Angulation in the sagittal plane,

c) Rotation in the transverse plane [1].

Scoliosis Classification (Figure 1):

1) Congenital scoliosis (Figure 2).

2) Neuromuscular Scoliosis [4]: This is arising as a result of neurologic or muscular disorders.

a) Neuropathic causes include

· Upper Motor Neuron Lesions, such as cerebral palsy, spinocerebellar degeneration, syringomyelia, spinal cord tumors, and trauma [5].

· Lower Motor Neuron Lesions, such as poliomyelitis, spinal muscular atrophy, and myelomeningocele [6].

b) Myopathic Conditions include muscular dystrophies [7].

3) Idiopathic Scoliosis [8]:

· Idiopathic Scoliosis is a diagnosis of exclusion, so neurological causes for the deformity must be ruled out by medical history, clinical examination, radiographs, and in selected cases by axial imaging [9]. It is the most common type which accounts for up to 80% of scoliosis in children [10].

· It is classified based on the age of onset into; -

i) Infantile (0 - 3 years), accounts for less than 1%, common in boys, convex left curves.

ii) Juvenile (3 - 10 years), makes up between 12% and 21%

iii) Adolescence (>10 years), the most common is about 90% of cases [11].

· These 3 periods mark the different periods of growth velocity during childhood; hence, the curves behave differently [12].

· More recently childhood scoliosis is divided into two categories; early-onset, (<5 years), late-onset (>5 years) [13].

This may be a more appropriate division as:

i) Growth velocity of the spine peaks between birth and the age of five,

ii) Treatment methods for patients with scoliosis when younger than 5 years is significantly different from patients presenting with scoliosis when older than 5 years,

iii) Periods of pulmonary development; from 0 to 5 years of age is the period of major pulmonary development, so cardiopulmonary complications are more likely seen when onset occurs before the age of five [14].

Curves are at risk for progression

1) During periods of rapid skeletal growth, specifically the first 2 years of life and the adolescent growth spurt.

2) Large curves.

3) Skeletally immature patients especially with curves greater than 20.

4) Thoracic and double curve patterns are at higher risk of progression than thoracolumbar curves.

5) Curve Degree, Curves less than 30 degrees at skeletal maturity are thought to be mostly stable and unlikely to progress over time. Curves greater than 50 degrees at skeletal maturity commonly progress at a rate of up to 1 degree per year for thoracic curves. Curves between 35 and 50 degrees at skeletal maturity present a diagnostic dilemma due to insufficient clinical data and should be followed radiographically into adulthood [15].

Radiological Evaluation

· Imaging modalities such as plain radiography, computed tomography (CT), and magnetic resonance (MR) imaging play vital roles in the diagnosis of scoliosis,

· In interpreting the imaging features of scoliosis, it is essential to identify the significance of vertebrae in or near the curved segment, the curve type, the degree of angulation, the degree of vertebral rotation, and the longitudinal extent of spinal involvement [16].

· Plain films (Figure 3) to assess and document the actual bony anatomy. The following views are requested: -

i) Posteroanterior (PA) (standing, erect sitting, or supine).

ii) Lateral: The PA and lateral radiographs should include the whole spine, shoulders, and pelvis to allow assessment of the patient’s overall skeletal balance as well as skeletal maturity. The curves are described by the direction of the convexity and the location of the apex.

iii) Side-bending films or lateral-bending films assess the flexibility of the curve [17] [18].

· If a neuraxial cause is being sought, magnetic resonance (MR) imaging of the entire brain and spinal cord is indicated, MR imaging helps assess the craniocervical junction, any split cord malformations, and tethering of the cord. There is an increasing trend to obtain an MRI scan for any patient requiring operative treatment of their scoliosis to rule out any unexpected intraspinal abnormality [19]. So, MRI is indicated for

o All patients presenting with early-onset scoliosis [20].

o For Patients with Abnormal Neurologic Examination [20].

o It is not routinely performed for patients with AIS, except for those with Pain, Atypical Curve patterns Large Curves on Presentation, or Rapidly Progressive curves [21].

Treatment

· Early-onset idiopathic scoliosis is treated to prevent future cardiopulmonary problems, whereas treatment for late-onset idiopathic scoliosis is done to ease deformity and improve the appearance, and to prevent significant psychosocial distress [23].

· Early-onset idiopathic scoliosis is the only type of scoliosis that benefit from nonoperative treatment

· Because the natural history of AIS at skeletal maturity is the continued progression of the curve into adulthood only if the deformity is greater than 50, the ultimate goal of the treatment of AIS is to keep scoliosis less than 50 at maturity [21].

· The treatment choices are based on several factors, including curve magnitude, type and location of the curve, level of maturity, remaining growth, cosmetic appearance, and patient psychosocial factors [11].

Treatment for scoliosis: includes

1) Observation [24].

2) Bracing or casting [25]: Bracing is typically indicated in: -

➢ Growing children (skeletally immature patients, Risser 0 or 1, 2) and in females who are less than 12 months past menarche) with Progressive curves (Curves that progress by 5 to 10 degrees at 6-month interval) measuring 20 to 45 degrees,

➢ The goal of bracing is to prevent curve progression and to keep it below the surgical range at skeletal maturity [26].

➢ Bracing and surgery are the mainstays for the treatment of scoliosis [27].

3) Surgery

➢ The goal of surgical treatment is to arrest the curve progression while improving spinal balance and alignment [28].

➢ Surgery (Fusion with instrumentation) is indicated for:

- Curves 45 degrees in growing children,

- For curves 50 degrees at maturity, and

- For those curves that continue to progress after the cessation of brace treatment [28] [29].

➢ Surgical options include either: -

- Anterior Release or

- Posterior Fusion to improve correction and prevent subsequent rotational and coronal deformity [30].

Aim of the study: This study was conducted to evaluate patients with idiopathic kyphoscoliosis who underwent a freehand posterior approach for scoliosis correction through transpedicular screws fixation.

Of the 12 patients with idiopathic kyphoscoliosis who underwent freehand surgical correction:

· 9 patients were female, 3 were male.

· Mean age 15 years ranged from (7 - 23).

· 8 cases with a thoracolumbar curve, 4 cases with the thoracic curve.

· 9 cases presented with deformity and back and 3 cases with deformity alone (Table 1).

Outcome

Early follow up

Cobb’s angle and coronal balance improved significantly after surgery 95% correction in 2 cases (17%), 80% correction in 8 cases (66%), 60% correction in 2 cases (17%).

2 cases have CSF leakage which improved with conservative treatment.

1 case has mal directed screw into disc space, and 1 case has a medial screw into the spinal canal without neurological deficit and no additional procedures was needed.

Late follow up: every 3 months for at least 12 months:

· Improvement of patient deformity and cosmetic appearance to the degree of patient satisfaction occur in 7 cases (58%) associated with high SRS-30 total scores.

· However, assessment of the pain in comparison to preoperative assessment show improvement of pain in 4 cases (33%), persistent in 4 cases (33%), appear in 4 cases (33%).

Case Presentation

· Male patient 16 years old, presented with back deformity with cobb’s angle 50 degrees (Figure 4).

· Postoperative (Figure 5):

- Cobb’s angle 10 without complication.

- The patient’s back appearance was improved and the patient was satisfied, but back pain that need medication and physiotherapy was present.

This study was performed on 12 patients with idiopathic kyphoscoliosis who underwent freehand surgical correction: 9 patients were female, 3 were male. Mean age 15 years ranged from (7 - 23). 8 cases with a thoracolumbar curve, 4 cases with the thoracic curve. 9 cases presented with deformity and back pain and 3 cases with deformity alone.

The early outcome showed Cobb’s angle and coronal balance improved significantly after surgery 95% correction in 2 cases (17%), 80% correction in 8 cases (66%), 60% correction in 2 cases (17%) which came in the agreement of Patel et al., 2018 [31], Min et al., 2013 [32], Lenke et al., 2010 [33] and Olgun and Yazici, 2013 [34] .

Patel et al., 2018 reported that the mean preoperative Cobb angle was 96.54˚, the mean postoperative angle was 30.77˚, and the mean angle at final follow-up was 34.81˚ (average loss of correction of 4.23˚), for a final average correction of 64.15%. Concerning scoliosis, the mean preoperative angle was 52.54˚, the mean postoperative angle was 15.77˚, and the mean angle at final follow-up was 19.42˚ (average loss of correction of 3.66˚), for a final average correction of 60.95% [31] .

Min et al., 2013 reported a 79.1% correction rate which is higher than most of the previously reported studies using all pedicle screws, which ranged between 62% and 77% [32] .

Lenke et al., 2010 reported that The severe scoliosis cases had a correction rate of 69%, 54% for the global kyphosis cases, 63% for the angular kyphosis cases, and 56% for the combined kyphoscoliosis cases [33] .

Olgun and Yazici 2013 reviewed the advantages of anterior versus posterior surgery and concluded that with modern pedicle screws, posterior surgery provides most, if not all, of the advantages of anterior surgery without its negative effect on pulmonary function [34] .

Also, the early outcome showed 2 cases have CSF leakage which improved with conservative treatment. 1 case has mal-directed screw into disc space, and 1 case has medial screw into the spinal canal without neurological deficit which came in the agreement of Bakaloudis et al, 2011 [35], Dhurve & Patil, 2017 [36] and Patel et al., 2018 [31] .

Dhurve & Patil, 2017 reported that the incidence of screw misplacement ranges from 3% to 44.2%, with screw-related neurologic complications in the 0% to 0.9% range. Also reported medial wall violation of the thoracic pedicle between 1.4% and 14% from 1mm to 8.0 mm, there were no permanent neurologic, cardiovascular, or pulmonary complications associated medial wall violation in many cases [36] .

Patel et al., 2018 reported that the overall complication rate was 30.77%. There was a general complication rate of 15%, which included 2 cases of dural tear and 1 case each of implant failure and superficial infection. The neurological complication rate was 7.6%. One patient had a new-onset neurological deficit involving the left L-4 nerve root (quadriceps weakness 3/5), and in 2 other patients, the neurological examination results worsened from preoperative Frankel grade C to A in the immediate postoperative period. In these 3 cases, the patients’ deficits all had improved with conservative management at the 3-month follow-up [31] .

Bakaloudis et al. 2011 reported 5 medical complications and 1 neurological complication in their series of 12 patients, for a complication rate of 50% [35] .

Late follow up which is done every 3 months for at least 12 months shows improvement of patient deformity and cosmetic appearance to the degree of patient satisfaction (in 7 cases (58%) associated with high SRS-30 total scores). However assessment of the pain in comparison to preoperative assessment show improvement of pain in 4 cases (33%), persistent in 4 cases (33%), and appear in 4 cases (33%) which came in the agreement of Cuartas et al., 2009 [37], Dong et al., 2021 [38] and Yilmaz et al., 2012 [39] .

Dong et al., 2021 reported that 52 patients were treated with freehand, and a total of 888 screws were placed. The average preoperative Cobb angle of the patients was 52.0˚ ± 15.7˚ (21˚ - 103˚), and the screw placement satisfaction rate reached 88.5%. No screw-related complications occurred. The overall screw placement in this trial was satisfied [38] .

Cuartas et al., 2009 reported that there is also evidence suggestive that the posterior-only surgery with pedicle screw instrumentation for AIS is associated with improved clinical outcomes including improved SRS scores [37] .

Yilmaz et al., 2012 reported that The optimal implants for posterior fixation should achieve better curve correction with high safety profile and minimal implant-related complications [39] .

To conclude, freehand one-stage correction for management of idiopathic kyphoscoliosis though the posterior approach is a safe and effective method for near-total correction of spinal deformity with a good functional outcome with minimal complications.

Patients had informed consent.

All the listed authors contributed significantly to the conception and design of study, acquisition, analysis, and interpretation of data and drafting of the manuscript, to justify authorship.

The author declares no conflicts of interest regarding the publication of this paper.

Aboelkhir, M. (2022) Free Hand One Stage Correction of Kyphoscoliosis. Open Journal of Modern Neurosurgery, 12, 47-59. https://doi.org/10.4236/ojmn.2022.121005