<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article  PUBLIC "-//NLM//DTD Journal Publishing DTD v3.0 20080202//EN" "http://dtd.nlm.nih.gov/publishing/3.0/journalpublishing3.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="3.0" xml:lang="en" article-type="research article"><front><journal-meta><journal-id journal-id-type="publisher-id">OJAnes</journal-id><journal-title-group><journal-title>Open Journal of Anesthesiology</journal-title></journal-title-group><issn pub-type="epub">2164-5531</issn><publisher><publisher-name>Scientific Research Publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.4236/ojanes.2021.118024</article-id><article-id pub-id-type="publisher-id">OJAnes-111628</article-id><article-categories><subj-group subj-group-type="heading"><subject>Articles</subject></subj-group><subj-group subj-group-type="Discipline-v2"><subject>Medicine&amp;Healthcare</subject></subj-group></article-categories><title-group><article-title>
 
 
  Should We Pay More Attention to Endotracheal Tube Fixation during Anesthesia—Surveys from Chinese Anesthesiologists for Endotracheal Tube Fixation and Endotracheal Tube Displacement in 2014 and 2020
 
</article-title></title-group><contrib-group><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Dongxue</surname><given-names>Li</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Tongfeng</surname><given-names>Luo</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Chuling</surname><given-names>Liu</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Xi</surname><given-names>Hong</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Sanqing</surname><given-names>Jin</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="corresp" rid="cor1"><sup>*</sup></xref></contrib></contrib-group><aff id="aff1"><addr-line>Department of Anesthesia, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China</addr-line></aff><pub-date pub-type="epub"><day>02</day><month>08</month><year>2021</year></pub-date><volume>11</volume><issue>08</issue><fpage>243</fpage><lpage>258</lpage><history><date date-type="received"><day>8,</day>	<month>July</month>	<year>2021</year></date><date date-type="rev-recd"><day>28,</day>	<month>August</month>	<year>2021</year>	</date><date date-type="accepted"><day>31,</day>	<month>August</month>	<year>2021</year></date></history><permissions><copyright-statement>&#169; Copyright  2014 by authors and Scientific Research Publishing Inc. </copyright-statement><copyright-year>2014</copyright-year><license><license-p>This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/</license-p></license></permissions><abstract><p>
 
 
  <b>Background:</b> Displacement of endotracheal tube (ETT) can result in endobronchial intubation and accidental extubation that severely threatens safety of surgical patients. However, few surveys have investigated intraoperative ETT displacement experienced by anesthesiologists. The objective of these surveys was to investigate ETT fixation method and ETT displacement during general anesthesia experienced by anesthesiologists in China in 2014 and 2020. 
  <b>Methods:</b> A questionnaire was designed with twenty questions and randomly distributed to anesthesiologists in two survey methods. In 2014, we collected responses from anesthesiologists who participated in the 22nd annual meeting of the Chinese Society of Anesthesiology in a face-to-face setting; in 2020, anesthesiologists from twenty-eight provinces completed the questionnaire through an online questionnaire survey platform. Differences in the responses from the anesthesiologists in 2014 and 2020 were assessed with a chi-square test. 
  <b>Results:</b> In total, 568 questionnaires were collected, of which 541 questionnaires were valid (valid response rate 95.2%). A majority of the respondents (65.6%) had experienced ETT displacement, and 4.3% of respondents had experienced serious complications due to ETT displacement. Three hundred and twenty-nine respondents (60.8%) fixed the ETT with adhesive tape in the shape of the letter X. A majority of respondents considered the influence of surgical site, body position (97.8% of all respondents), and age (77.1% of all respondents) on fixing the ETT. Adhesive tape was the most commonly used material to fix the ETT (90.4% of the respondents). 
  <b>Conclusion:</b> During clinical anesthesia, a majority of anesthesiologists experienced ETT displacement that can result in serious consequences. Therefore, the management of ETT should be a priority during the operation.
 
</p></abstract><kwd-group><kwd>Anesthesia</kwd><kwd> Endotracheal Tube</kwd><kwd> Displacement</kwd><kwd> Fixation</kwd><kwd> Questionnaires</kwd></kwd-group></article-meta></front><body><sec id="s1"><title>1. Introduction</title><p>Securing the endotracheal tube (ETT) following intubation is a routine procedure during general anesthesia with tracheal intubation. Proper fixation of the ETT is crucial for effective ventilation during general anesthesia while minimizing potential complications due to ETT displacement. Displacement of the ETT can result in endobronchial intubation and accidental extubation [<xref ref-type="bibr" rid="scirp.111628-ref1">1</xref>]. If unrecognized, endobronchial intubation can lead to hypoxemia caused by atelectasis formation in the unventilated lung, and hyperinflation and barotrauma with the development of pneumothorax of the intubated lung [<xref ref-type="bibr" rid="scirp.111628-ref2">2</xref>]. Accidental extubation can lead to serious complications, such as laryngeal injury, vocal cord injury, aspiration, respiratory arrest, arrhythmias, hypoxemia, hypotension, cardiac arrest, anoxic brain injury, or even death [<xref ref-type="bibr" rid="scirp.111628-ref3">3</xref>] - [<xref ref-type="bibr" rid="scirp.111628-ref8">8</xref>].</p><p>Although many methods of securing ETT, including adhesive tapes, sutures, silk ties, commercial ETT holders, umbilical cord clamps, or a combination of these techniques have been used to reduce the displacement of ETT, the best method of securing ETT remains a controversial issue [<xref ref-type="bibr" rid="scirp.111628-ref9">9</xref>] - [<xref ref-type="bibr" rid="scirp.111628-ref14">14</xref>]. Additionally, anesthesia textbooks do not describe how to fix ETT in detail. The case reports of accidental extubation during general anesthesia can still be found in recent years [<xref ref-type="bibr" rid="scirp.111628-ref7">7</xref>] [<xref ref-type="bibr" rid="scirp.111628-ref15">15</xref>] [<xref ref-type="bibr" rid="scirp.111628-ref16">16</xref>] [<xref ref-type="bibr" rid="scirp.111628-ref17">17</xref>] [<xref ref-type="bibr" rid="scirp.111628-ref18">18</xref>] [<xref ref-type="bibr" rid="scirp.111628-ref19">19</xref>], however, the cases of ETT displacement and its consequences might be underestimated in the literature.</p><p>Therefore, the objective of the surveys was to investigate how many anesthesiologists had ever experienced the ETT displacement and its consequences during anesthesia, and the surveys were performed in 2014 and 2020 respectively, in China. The results for 2014 with those for 2020 were compared to investigate the advance in ETT fixation methods. This survey will provide preliminary information on ETT fixation methods, ETT displacement frequency and the possible factors to cause ETT displacement.</p></sec><sec id="s2"><title>2. Methods</title><sec id="s2_1"><title>2.1. Questionnaire Design</title><p>The relevant literature was searched through the PubMed medical literature retrieval system with keywords, such as “accidental extubation”, “endotracheal tube”, “displacement”, “fixation”, and “questionnaire survey”. According to the results of the literature search and the experience of ETT securement in the clinic, we designed the questionnaire.</p><p>The questionnaire consisted of twenty questions, which involved the characteristics of respondents, the ETT fixation methods, the ETT displacement and its consequences experienced by the anesthesiologists, and the factors influencing the anesthesiologists to determine the method of fixing the ETT (for details, see supplementary materials).</p></sec><sec id="s2_2"><title>2.2. Respondents and Investigated Methods</title><p>One hundred and eighty questionnaires were randomly distributed to anesthesiologists who participated in the 22nd annual meeting of Chinese Society of Anesthesiology in Chengdu, China on September 12th and 13th, 2014. The questionnaires were promptly returned after being answered. In 2020, the questionnaires were distributed and collected through the “questionnaire star” online questionnaire survey platform via WeChat, and 378 anesthesiologists from twenty-eight provinces in China volunteered to complete the questionnaires from August 28th to 30th.</p><p>All of the respondents should have more than one year of clinical anesthesia working experience. Interns and anesthesiologists assistants were excluded from this survey. Before completing and submitting the survey, the anesthesiologists were informed about their consent to participate in the survey and authorized the researchers to analyze their responses. The anesthesiologists were informed that no identifiable information would be published or released.</p></sec><sec id="s2_3"><title>2.3. Data Collection</title><p>The questionnaires were collected and stored in department of anesthesia, the Sixth Affiliated Hospital, Sun Yat-sen University. The valid questionnaires were selected if they met the following requirements. First, the written responses to all of the questions were legible; second, there were no mistakes among the answers; third, there were no inherent contradictions among the answers.</p></sec><sec id="s2_4"><title>2.4. Statistical Analysis</title><p>The categorical variables were presented as number and percent. Continuous variables were presented as mean &#177; standard deviation (SD). Comparison of working experience between respondents in 2014 and 2020 was assessed with the Kruskal-Wallis test. Comparison of mean cases of ETT displacement experienced by respondents between 2014 and 2020 was assessed with the Mann-Whitney U test. Chi-square test with correction for continuity was used to compare the influence of surgical site and position on ETT fixation between 2014 and 2020. Comparison of other categorical variables was assessed with the chi-square test. Logistic regression was used to analyze the relationship between ETT displacement and professional titles, fixing ETT by themselves or not, fixation materials, fixation methods, whether to place bite block, fixation methods after bite block, whether to consider the surgical site and position, and whether to consider the age. The forward method was used as the screening method of the independent variable. Statistical analysis was performed by SPSS 16.0 (SPSS Inc., USA). For all analyses, the two-tailed P value of less than 0.05 was considered statistically significant.</p></sec></sec><sec id="s3"><title>3. Results</title><sec id="s3_1"><title>3.1. Characteristics of the Respondents</title><p>A total of 568 questionnaires were collected, of which 541 were valid (valid response rate 95.2%). The respondents were from 28 provinces in China. The province distribution of the respondent’s hospital is shown in <xref ref-type="fig" rid="fig1">Figure 1</xref>.</p><p>The constituent ratios of hospital category, hospital grade, professional title, work experience, and cases of endotracheal intubation performed per month are shown in <xref ref-type="table" rid="table1">Table 1</xref>. Approximately 60% of respondents had the professional title</p><table-wrap id="table1" ><label><xref ref-type="table" rid="table1">Table 1</xref></label><caption><title> The characteristics of respondents</title></caption><table><tbody><thead><tr><th align="center" valign="middle" >Variables</th><th align="center" valign="middle" >All respondents</th><th align="center" valign="middle" >Respondents in 2014</th><th align="center" valign="middle" >Respondents in 2020</th><th align="center" valign="middle" >P value</th></tr></thead><tr><td align="center" valign="middle" ></td><td align="center" valign="middle" >n = 541</td><td align="center" valign="middle" >n = 179</td><td align="center" valign="middle" >n = 362</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Hospital category</td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >General hospital</td><td align="center" valign="middle" >435 (80.4%)</td><td align="center" valign="middle" >144 (80.4)</td><td align="center" valign="middle" >291 (80.4%)</td><td align="center" valign="middle" >0.987</td></tr><tr><td align="center" valign="middle" >Specialized hospital</td><td align="center" valign="middle" >106 (19.6%)</td><td align="center" valign="middle" >35 (19.6%)</td><td align="center" valign="middle" >71 (19.6%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Hospital grade*</td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Grade 3 class A</td><td align="center" valign="middle" >409 (75.6%)</td><td align="center" valign="middle" >146 (81.6%)</td><td align="center" valign="middle" >263 (72.7%)</td><td align="center" valign="middle" >0.023</td></tr><tr><td align="center" valign="middle" >Below grade 3 class A</td><td align="center" valign="middle" >132 (24.4%)</td><td align="center" valign="middle" >33 (18.4%)</td><td align="center" valign="middle" >99 (27.3%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Professional titles*</td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Chief physician</td><td align="center" valign="middle" >22 (4.1%)</td><td align="center" valign="middle" >16 (18.9%)</td><td align="center" valign="middle" >6 (1.7%)</td><td align="center" valign="middle" >0.010</td></tr><tr><td align="center" valign="middle" >Associate chief physician</td><td align="center" valign="middle" >115 (21.3%)</td><td align="center" valign="middle" >41 (22.9%)</td><td align="center" valign="middle" >74 (20.4%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Attending physician</td><td align="center" valign="middle" >188 (34.7%)</td><td align="center" valign="middle" >55 (30.7%)</td><td align="center" valign="middle" >133 (36.7%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Resident physician</td><td align="center" valign="middle" >216 (39.9%)</td><td align="center" valign="middle" >67 (37.4%)</td><td align="center" valign="middle" >149 (41.2%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Work experience (years)</td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >1 - 5</td><td align="center" valign="middle" >197 (36.4%)</td><td align="center" valign="middle" >66 (36.9%)</td><td align="center" valign="middle" >131 (36.2%)</td><td align="center" valign="middle" >0.305</td></tr><tr><td align="center" valign="middle" >6 - 10</td><td align="center" valign="middle" >112 (20.7%)</td><td align="center" valign="middle" >35 (19.6%)</td><td align="center" valign="middle" >77 (21.3%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >11 - 15</td><td align="center" valign="middle" >135 (25.0%)</td><td align="center" valign="middle" >31 (17.3%)</td><td align="center" valign="middle" >104 (28.7%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >16 - 20</td><td align="center" valign="middle" >57 (10.5%)</td><td align="center" valign="middle" >29 (16.2%)</td><td align="center" valign="middle" >28 (7.7%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >&gt;20</td><td align="center" valign="middle" >40 (7.4%)</td><td align="center" valign="middle" >18 (10.1%)</td><td align="center" valign="middle" >22 (6.1%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >The case of endotracheal tube used per month</td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >1 - 25</td><td align="center" valign="middle" >92 (17.0%)</td><td align="center" valign="middle" >25 (14%)</td><td align="center" valign="middle" >67 (18.5%)</td><td align="center" valign="middle" >0.214</td></tr><tr><td align="center" valign="middle" >26 - 50</td><td align="center" valign="middle" >221 (40.9%)</td><td align="center" valign="middle" >66 (36.9%)</td><td align="center" valign="middle" >155 (42.8%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >51 - 75</td><td align="center" valign="middle" >97 (17.9%)</td><td align="center" valign="middle" >37 (20.7%)</td><td align="center" valign="middle" >60 (16.6%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >76 - 100</td><td align="center" valign="middle" >95 (17.6%)</td><td align="center" valign="middle" >38 (21.2%)</td><td align="center" valign="middle" >57 (15.7%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >&gt;100</td><td align="center" valign="middle" >36 (6.6%)</td><td align="center" valign="middle" >13 (7.3%)</td><td align="center" valign="middle" >23 (6.4%)</td><td align="center" valign="middle" ></td></tr></tbody></table></table-wrap><p>Data are expressed as the number of the respondents (percentage). Compared variables between 2014 and 2020,*P &lt; 0.05.</p><p>of attending physician or higher. The constituent ratios of the respondents’ professional titles between 2014 and 2020 had significant differences (P = 0.01), fewer chief physicians took part in 2020’s survey. More than 60% of respondents had more than 5 years of work experience and 83% of respondents performed more than 25 cases of endotracheal intubations per month.</p></sec><sec id="s3_2"><title>3.2. ETT Fixation Methods in Clinical Anesthesia</title><p>As shown in <xref ref-type="table" rid="table2">Table 2</xref>, 77.8% of the respondents indicated that they could fix ETT by themselves after intubation. In comparison to respondents in 2014, proportionately higher numbers of respondents fixed ETT by themselves in 2020 (67.7% vs. 82.9%, P &lt; 0.001). Among the respondents, 90.4% indicated they routinely secured the ETT with adhesive tape, including silk medical adhesive tape (49.5%) and plastic medical adhesive tape (40.9%).</p><p>A total of 60.8% of respondents stated that they fixed ETT in the shape of the letter X, using two pieces of adhesive tapes of appropriate length and width, where one piece of tape was attached to one side of the cheek, wrapped around the tube two circles, and subsequently cross-fixed on the same side of the cheek, and the other piece of tape was attached to the other side of the cheek, wrapped around the tube two circles, and then cross-fixed on the same side. In comparison to respondents in 2020, proportionately higher numbers of respondents in 2014 fixed ETT in the shape of the letter X (P &lt; 0.001) (<xref ref-type="table" rid="table2">Table 2</xref>).</p><p>And 87.6% of the respondents stated that they usually placed a bite block after endotracheal intubation, proportionately fewer respondents place a bite block in 2020. When placing a bite block, proportionately fewer respondents first secured the ETT and then fixed the bite block with the ETT in 2014 compared to 2020 (44.1% vs. 52.8%, P = 0.004) (<xref ref-type="table" rid="table2">Table 2</xref>).</p></sec><sec id="s3_3"><title>3.3. ETT Displacement and Consequences</title><p>Among the respondents, 65.6% (355/541) had experienced ETT displacement.</p><table-wrap id="table2" ><label><xref ref-type="table" rid="table2">Table 2</xref></label><caption><title> The endotracheal tube fixation status in clinical anesthesia</title></caption><table><tbody><thead><tr><th align="center" valign="middle" >Variables</th><th align="center" valign="middle" >All respondents</th><th align="center" valign="middle" >Respondents in 2014</th><th align="center" valign="middle" >Respondents in 2020</th><th align="center" valign="middle" >P value</th></tr></thead><tr><td align="center" valign="middle" ></td><td align="center" valign="middle" >n = 541</td><td align="center" valign="middle" >n = 179</td><td align="center" valign="middle" >n = 362</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Fixing endotrachea tube by themselves or not*</td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >By themselves</td><td align="center" valign="middle" >421 (77.8%)</td><td align="center" valign="middle" >121 (67.7%)</td><td align="center" valign="middle" >300 (82.9%)</td><td align="center" valign="middle" >&lt;0.001</td></tr><tr><td align="center" valign="middle" >By others under their supervision</td><td align="center" valign="middle" >109 (20.2%)</td><td align="center" valign="middle" >54 (30.2%)</td><td align="center" valign="middle" >55 (15.2%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >By others</td><td align="center" valign="middle" >11 (2.0%)</td><td align="center" valign="middle" >4 (2.2%)</td><td align="center" valign="middle" >7 (1.9%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Fixation materials</td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Silk medical adhesive tape</td><td align="center" valign="middle" >268 (49.5%)</td><td align="center" valign="middle" >86 (48.0%)</td><td align="center" valign="middle" >182 (50.3%)</td><td align="center" valign="middle" >0.758</td></tr><tr><td align="center" valign="middle" >Plastic medical adhensive tape</td><td align="center" valign="middle" >221 (40.9%)</td><td align="center" valign="middle" >77 (43.0%)</td><td align="center" valign="middle" >144 (39.8%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Transparent film dressing + Bangage + others</td><td align="center" valign="middle" >52 (9.6%)</td><td align="center" valign="middle" >16 (9.0%)</td><td align="center" valign="middle" >36 (9.9%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Fixation methods*</td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Fix the endotracheal tube in the shape of the letter X</td><td align="center" valign="middle" >329 (60.8)</td><td align="center" valign="middle" >133 (74.3%)</td><td align="center" valign="middle" >196 (54.1%)</td><td align="center" valign="middle" >&lt;0.001</td></tr><tr><td align="center" valign="middle" >Other fixation methods</td><td align="center" valign="middle" >212 (39.2)</td><td align="center" valign="middle" >46 (25.7%)</td><td align="center" valign="middle" >166 (45.9%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Placing the bite block*</td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Yes</td><td align="center" valign="middle" >474 (87.6%)</td><td align="center" valign="middle" >165 (92.2%)</td><td align="center" valign="middle" >309 (85.4%)</td><td align="center" valign="middle" >0.023</td></tr><tr><td align="center" valign="middle" >No</td><td align="center" valign="middle" >67 (12.4)</td><td align="center" valign="middle" >14 (7.8%)</td><td align="center" valign="middle" >53 (14.6%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Fixation methods when placing a bite block*</td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Method a</td><td align="center" valign="middle" >244 (45.1%)</td><td align="center" valign="middle" >97 (54.2%)</td><td align="center" valign="middle" >147 (40.6%)</td><td align="center" valign="middle" >0.004</td></tr><tr><td align="center" valign="middle" >Method b</td><td align="center" valign="middle" >270 (49.9%)</td><td align="center" valign="middle" >79 (44.1%)</td><td align="center" valign="middle" >191 (52.8%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Method c</td><td align="center" valign="middle" >10 (1.9%)</td><td align="center" valign="middle" >2 (1.1%)</td><td align="center" valign="middle" >8 (2.2%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Method d</td><td align="center" valign="middle" >17 (3.1%)</td><td align="center" valign="middle" >1 (0.6%)</td><td align="center" valign="middle" >16 (4.4%)</td><td align="center" valign="middle" ></td></tr></tbody></table></table-wrap><p>Data are expressed as the number of the respondents (percentage). The shape of letter X: Using two pieces of adhesive tapes of appropriate length and width, where one piece of tape was attached to one side of the cheek, wrapped around the tube two circles, and subsequently cross-fixed on the same side of the cheek, and the other piece of tape was attached to the other side of the cheek, wrapped around the tube two circles, and then cross-fixed on the same side. Method a: fixed the bite block and tube together. Method b: First fixed the endotracheal tube and then fixed the bite block with the tube. Method c: Fixed the endotracheal tube and bite block completely separately. Method d: Only fixed the endotracheal tube, not the bite block. Compared variables between 2014 and 2020, *P &lt; 0.05.</p><p>Proportionately higher numbers of respondents in 2014 had experienced the ETT displacement compared with respondents in 2020 (72.1% vs. 62.4%, P = 0.026) (<xref ref-type="fig" rid="fig2">Figure 2</xref>). The mean cases of ETT displacement experienced by respondents in 2020 were more than that in 2014 (4.7 &#177; 5.4 vs. 3.5 &#177; 4.4, P &lt; 0.001). A minority of the respondents (23/541, 4.3%) indicated that they had experienced serious consequences caused by ETT displacement, including hypoxemia (7/541), atelectasis (9/541), cardiac arrest (2/541), death (2/541) and other complications (3/541) (<xref ref-type="fig" rid="fig3">Figure 3</xref>).</p></sec><sec id="s3_4"><title>3.4. The Factors Influencing the Anesthesiologists to Determine the Method of ETT Fixation</title><p>Among the respondents, 97.8% stated that they considered the influence of surgical site and position on ETT fixation, and 77.1% took the age of patients into account when securing the ETT. Proportionately higher numbers of respondents considered the influence of age on ETT fixation in 2014 compared with respondents in 2020 (P &lt; 0.001) (<xref ref-type="table" rid="table3">Table 3</xref>). The fixation materials used in head and neck surgery, prone surgery and pediatric surgery are shown in <xref ref-type="table" rid="table3">Table 3</xref>.</p><p>As for patients in the supine position underwent except head and neck surgery,</p><table-wrap id="table3" ><label><xref ref-type="table" rid="table3">Table 3</xref></label><caption><title> The factors influencing the anesthesiologist to determine the method of fixing the endotrachea tube</title></caption><table><tbody><thead><tr><th align="center" valign="middle" >Variables</th><th align="center" valign="middle" >All respondents</th><th align="center" valign="middle" >Respondents in 2014</th><th align="center" valign="middle" >Respondents in 2020</th><th align="center" valign="middle" >P value</th></tr></thead><tr><td align="center" valign="middle" >Influence of surgical site and position</td><td align="center" valign="middle" >n = 541</td><td align="center" valign="middle" >n = 179</td><td align="center" valign="middle" >n = 362</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Consider</td><td align="center" valign="middle" >529 (97.8%)</td><td align="center" valign="middle" >177 (98.9%)</td><td align="center" valign="middle" >352 (97.2%)</td><td align="center" valign="middle" >0.362</td></tr><tr><td align="center" valign="middle" >Not consider</td><td align="center" valign="middle" >12 (2.2%)</td><td align="center" valign="middle" >2 (1.1%)</td><td align="center" valign="middle" >10 (2.8%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Influence of age*</td><td align="center" valign="middle" >n = 541</td><td align="center" valign="middle" >n = 179</td><td align="center" valign="middle" >n = 362</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Consider</td><td align="center" valign="middle" >417 (77.1%)</td><td align="center" valign="middle" >153 (85.5%)</td><td align="center" valign="middle" >264 (72.9%)</td><td align="center" valign="middle" >0.001</td></tr><tr><td align="center" valign="middle" >Not consider</td><td align="center" valign="middle" >124 (22.9%)</td><td align="center" valign="middle" >26 (14.5%)</td><td align="center" valign="middle" >98 (27.1%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Fixation material used in head and neck surgery or prone surgery*</td><td align="center" valign="middle" >n = 529</td><td align="center" valign="middle" >n = 177</td><td align="center" valign="middle" >n = 352</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Method a</td><td align="center" valign="middle" >53 (10.0%)</td><td align="center" valign="middle" >21 (11.9%)</td><td align="center" valign="middle" >32 (9.1%)</td><td align="center" valign="middle" >0.005</td></tr><tr><td align="center" valign="middle" >Method b</td><td align="center" valign="middle" >170 (32.1%)</td><td align="center" valign="middle" >72 (40.7%)</td><td align="center" valign="middle" >98 (27.8%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Method c</td><td align="center" valign="middle" >275 (52.0%)</td><td align="center" valign="middle" >73 (41.2%)</td><td align="center" valign="middle" >202 (57.4%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Method d</td><td align="center" valign="middle" >31 (5.9%)</td><td align="center" valign="middle" >11 (6.2%)</td><td align="center" valign="middle" >20 (5.7%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Fixation material used in pediatric surgery</td><td align="center" valign="middle" >n = 417</td><td align="center" valign="middle" >n = 153</td><td align="center" valign="middle" >n = 264</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Method a</td><td align="center" valign="middle" >100 (24.0%)</td><td align="center" valign="middle" >29 (19.0%)</td><td align="center" valign="middle" >71 (26.9%)</td><td align="center" valign="middle" >0.132</td></tr><tr><td align="center" valign="middle" >Method b</td><td align="center" valign="middle" >138 (33.1%)</td><td align="center" valign="middle" >59 (38.6%)</td><td align="center" valign="middle" >79 (29.9%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Method c</td><td align="center" valign="middle" >142 (34.0%)</td><td align="center" valign="middle" >54 (35.3%)</td><td align="center" valign="middle" >88 (33.3%)</td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Method d</td><td align="center" valign="middle" >37 (8.9%)</td><td align="center" valign="middle" >11 (7.2%)</td><td align="center" valign="middle" >26 (9.8%)</td><td align="center" valign="middle" ></td></tr></tbody></table></table-wrap><p>Data are expressed as the number of the respondents (percentage). Material a: Same as the materials for fixing general endotracheal tube; Material b: Reinforce tube with adhensive tape; Material c: Reinforce tube with transparent film dressing; Material d: Reinforce tube with other materials. *P &lt; 0.05.</p><p>the primary cause of ETT displacement is shown in <xref ref-type="fig" rid="fig4">Figure 4</xref>. The constituent ratios of the primary cause of ETT displacement between 2014 and 2020 were significantly different (P &lt; 0.05) (<xref ref-type="fig" rid="fig4">Figure 4</xref>).</p></sec><sec id="s3_5"><title>3.5. Logistic Analysis Results of Possible Factors to Cause ETT Displacement Experienced by Respondents</title><p>To analysis, the possible factors to cause the ETT displacement, respondents with and without ETT displacement were compared. Multivariate logistic regression model was established by including the professional title, fixing endotrachea tube by themselves or not, fixation materials, fixation methods, whether to place bite block, fixation methods after bite block, whether to consider the surgical site and position, and whether to consider age. The results shown that decrease in the professional title significantly increases the risk of ETT displacement (attending physician: OR = 2.08, 95% CI 1.27 - 3.42, P = 0.004; resident physician: OR = 2.41, 95% CI 1.56 - 3.71, P &lt; 0.001). The risk of ETT displacement was significantly increased without the placement of bite block (OR = 1.90, 95% CI 1.11 - 3.25, P = 0.02), without the consideration of surgical site or position (OR = 3.57, 95% CI 1.01 - 12.62, P = 0.048), and without the consideration of age (OR = 1.89, 95% CI 1.24 - 2.89, P = 0.003) (<xref ref-type="table" rid="table4">Table 4</xref>).</p><table-wrap id="table4" ><label><xref ref-type="table" rid="table4">Table 4</xref></label><caption><title> Logistic analysis results of the possible factors to cause endotracheal tube displacement experienced by responders</title></caption><table><tbody><thead><tr><th align="center" valign="middle"  rowspan="2"  >variables</th><th align="center" valign="middle"  rowspan="2"  >Coefficient</th><th align="center" valign="middle"  rowspan="2"  >Standard error</th><th align="center" valign="middle"  rowspan="2"  >Wald χ<sup>2</sup></th><th align="center" valign="middle"  rowspan="2"  >P</th><th align="center" valign="middle"  rowspan="2"  >OR</th><th align="center" valign="middle"  colspan="2"  >95% CI</th></tr></thead><tr><td align="center" valign="middle" >lower 95% CI</td><td align="center" valign="middle" >lower 95% CI</td></tr><tr><td align="center" valign="middle"  colspan="8"  >Professional titles</td></tr><tr><td align="center" valign="middle" >Chief physician*</td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >Associate chief physician</td><td align="center" valign="middle" >0.69</td><td align="center" valign="middle" >0.49</td><td align="center" valign="middle" >1.97</td><td align="center" valign="middle" >0.16</td><td align="center" valign="middle" >1.99</td><td align="center" valign="middle" >0.76</td><td align="center" valign="middle" >5.24</td></tr><tr><td align="center" valign="middle" >Attending physician</td><td align="center" valign="middle" >0.73</td><td align="center" valign="middle" >0.25</td><td align="center" valign="middle" >8.45</td><td align="center" valign="middle" >0.004</td><td align="center" valign="middle" >2.08</td><td align="center" valign="middle" >1.27</td><td align="center" valign="middle" >3.42</td></tr><tr><td align="center" valign="middle" >Resident physician</td><td align="center" valign="middle" >0.88</td><td align="center" valign="middle" >0.22</td><td align="center" valign="middle" >15.82</td><td align="center" valign="middle" >&lt;0.001</td><td align="center" valign="middle" >2.41</td><td align="center" valign="middle" >1.56</td><td align="center" valign="middle" >3.71</td></tr><tr><td align="center" valign="middle"  colspan="8"  >Placing the bite block</td></tr><tr><td align="center" valign="middle" >Yes*</td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >No</td><td align="center" valign="middle" >0.64</td><td align="center" valign="middle" >0.28</td><td align="center" valign="middle" >5.40</td><td align="center" valign="middle" >0.02</td><td align="center" valign="middle" >1.90</td><td align="center" valign="middle" >1.11</td><td align="center" valign="middle" >3.25</td></tr><tr><td align="center" valign="middle"  colspan="8"  >Consider the influence of surgical site and position</td></tr><tr><td align="center" valign="middle" >Yes*</td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >No</td><td align="center" valign="middle" >1.27</td><td align="center" valign="middle" >0.65</td><td align="center" valign="middle" >3.89</td><td align="center" valign="middle" >0.048</td><td align="center" valign="middle" >3.57</td><td align="center" valign="middle" >1.01</td><td align="center" valign="middle" >12.62</td></tr><tr><td align="center" valign="middle"  colspan="8"  >Consider the influence of age</td></tr><tr><td align="center" valign="middle" >Yes*</td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td><td align="center" valign="middle" ></td></tr><tr><td align="center" valign="middle" >No</td><td align="center" valign="middle" >0.64</td><td align="center" valign="middle" >0.216</td><td align="center" valign="middle" >8.67</td><td align="center" valign="middle" >0.003</td><td align="center" valign="middle" >1.89</td><td align="center" valign="middle" >1.24</td><td align="center" valign="middle" >2.89</td></tr></tbody></table></table-wrap><p>*represented reference category. OR: Odds ratio, CI: Confidence interval.</p></sec></sec><sec id="s4"><title>4. Discussion</title><p>The surveys indicate that a majority of anesthesiologists in China experienced ETT displacement during general anesthesia in 2014 and 2020. A minority of anesthesiologists even experienced cardiac arrest and death of patients due to ETT displacement. A majority of the respondents secured ETT in the shape of the letter X with adhesive tape. A majority of respondents considered the influence of surgical site, position, and age on securing the ETT, after which most of them would reinforce the ETT with other materials.</p><p>ETT displacement, especially accidental extubation, is a potentially life-threat-ening complication that can occur following intubation. However, literature on the incidence of accidental extubation and ETT displacement in surgical patients with general anesthesia remains limited. In our survey, among all participants, 65.6% had experienced ETT displacement, and 4.3% had experienced serious complications such as hypoxemia, cardiac arrest, or death due to ETT displacement. Although the incidence of ETT displacement experienced by anesthesiologists decreased by 9.7% in 2020 compared with that in 2014, it was still as high as 62.4%. A previous study has shown that 12% of the airway cases in the anesthesia closed claims analysis were caused by premature extubation [<xref ref-type="bibr" rid="scirp.111628-ref20">20</xref>]. In clinical anesthesia, preventing the ETT displacement and reducing the complications related to ETT displacement should be a priority.</p><p>There are many risk factors for ETT displacement in general anesthesia during surgery. Previous studies have shown that head and neck movement could lead to unexpected tube displacement [<xref ref-type="bibr" rid="scirp.111628-ref21">21</xref>] [<xref ref-type="bibr" rid="scirp.111628-ref22">22</xref>] [<xref ref-type="bibr" rid="scirp.111628-ref23">23</xref>] and patients who underwent a supine-to-prone position change were more likely to experience ETT displacement [<xref ref-type="bibr" rid="scirp.111628-ref24">24</xref>]. Additionally, children younger than 2 years presented greater unplanned extubation rates than children over 2 years [<xref ref-type="bibr" rid="scirp.111628-ref25">25</xref>]. Another study found that unplanned extubations were more common in children who were younger than 5 years compared with older children [<xref ref-type="bibr" rid="scirp.111628-ref26">26</xref>]. In our survey, lower profession title, without placing the bite block, without the consideration of surgical site or position and without the consideration of age were the risk factors of ETT displacement. So a majority of respondents had considered the influence of surgical site, position, and age on securing ETT. As such, a majority of respondents indicated that they reinforced the ETT with adhesive tape, transparent film dressing, or other materials.</p><p>Previous studies on the optimum fixation material and method have yielded contradictory results [<xref ref-type="bibr" rid="scirp.111628-ref9">9</xref>] [<xref ref-type="bibr" rid="scirp.111628-ref12">12</xref>] [<xref ref-type="bibr" rid="scirp.111628-ref13">13</xref>] [<xref ref-type="bibr" rid="scirp.111628-ref27">27</xref>]. Our survey found that there were differences in fixation methods between 2014 and 2020, the fixation materials did not change significantly. Adhesive tape was the most commonly used fixation material in clinical practice and only a minority of respondents routinely used other materials, including transparent film dressing, bandages, sutures, ETT-holders. The proportion of respondents who stated that improperly fixing ETT was the primary cause of ETT displacement was higher than that who indicated that poor quality of fixation materials led to ETT displacement (37.3% and 2.8%, respectively). In the opinion of respondents, the fixation methods were more critical than the fixation materials for preventing ETT displacement. Our survey showed a majority of respondents secured ETT with adhesive tape in the shape of the letter X. In addition, the fixation method in the shape of letter H, the fixation method in the shape of the letter Y, and other methods with adhesive tape are often used in clinical practice [<xref ref-type="bibr" rid="scirp.111628-ref28">28</xref>] [<xref ref-type="bibr" rid="scirp.111628-ref29">29</xref>]. The optimum fixation method needs to be explored.</p><p>So far, there are few surveys to investigate the ETT displacement experienced by anesthesiologists and consequences during general anesthesia. Among the respondents, 63.1% had been practicing for 6 or more years, and 60.1% had a professional title of attending physician or higher. All of the respondents were active in anesthesia clinical work, and 83% of the respondents performed more than 25 cases of ETT per month, indicating a high level of reliability of the questionnaire responses. Meanwhile, all the questionnaires were filled out anonymously, so the respondents did not have any relevant concerns. These measures ensured the authenticity and reliability of this survey.</p><p>The major limitation of this study was that the cases and the consequences of ETT displacement were reported solely by the memory of the respondent, and there might be some discrepancy between the respondents’ memory and the clinic records. Additionally, except for work experience and professional titles, other factors such as gender or educational background, might also affect the fixation of ETT, which we hope to address in our future work. Moreover, the differences in the survey methods may have led to differences in the characteristics of respondents. Compared with the online survey, a higher proportion of face-to-face respondents came from grade 3 class A hospitals and were chief physicians, which may have led to differences in the incidence of ETT displacement experienced by respondents between 2014 and 2020.</p></sec><sec id="s5"><title>5. Conclusion</title><p>In conclusion, a majority of anesthesiologists experienced ETT displacement, which may result in serious complications during general anesthesia. Therefore, management of the ETT should be paid more attention during the operation.</p></sec><sec id="s6"><title>Acknowledgements</title><p>We thank Hongbin Feng, Zijia Li, Zhinan Zheng, Shanmei Wu, Nanrong Zhang and all other colleagues in our department for their assistance in the collection of questionnaires. We thank the respondents for their participation in the investigation.</p></sec><sec id="s7"><title>Authors’ Contributions</title><p>Sanqing Jin designed the study and supervised the whole process of the study and revised the manuscript. Dongxue Li and Tongfeng Luo collected and analyzed the data, and wrote the manuscript. Chuling Liu and Xi Hong checked and analyzed the data. All authors read and approved the final version.</p></sec><sec id="s8"><title>Conflicts of Interest</title><p>The authors declare no conflicts of interest regarding the publication of this paper.</p></sec><sec id="s9"><title>Cite this paper</title><p>Li, D.X., Luo, T.F., Liu, C.L., Hong, X. and Jin, S.Q. (2021) Should We Pay More Attention to Endotracheal Tube Fixation during Anesthesia—Surveys from Chinese Anesthesiologists for Endotracheal Tube Fixation and Endotracheal Tube Displacement in 2014 and 2020. Open Journal of Anesthesiology, 11, 243-258. https://doi.org/10.4236/ojanes.2021.118024</p></sec><sec id="s10"><title>Supplementary Materials</title><p>Questionnaire of ETT displacement</p><p>Do you agree to participate?</p><p>Yes No</p><p>Your basic information</p><p>1) Your hospital</p><p>Province: City:</p><p>2) Your hospital is:</p><p>a) General hospital b) Specialized hospital</p><p>3) The grade of your hospital is:</p><p>a) Grade 3 class A b) Grade 3 class B c) Grade 2 class A</p><p>d) Grade 2 class B e) Other grades</p><p>4) Your work experience: ___ years</p><p>5) Your professional title:</p><p>a) Chief physician b) Association chief physician</p><p>c) Attending physician d) Resident physician</p><p>6) The cases of endotracheal intubation you performed per month in your memory:____</p><p>ETT fixation status in the clinic</p><p>7) Whether you fixed the ETT by yourself after the endotracheal intubation?</p><p>a) Fixed the ETT by yourself</p><p>b) Fixed the ETT by others under your supervision</p><p>c) Fixed the ETT by others</p><p>8) The material for fixing the ETT:</p><p>a) Silk medical adhesive tape b) Plastic medical adhesive tape</p><p>c) Transparent film dressing d) Baggage e) Others (ETT-holder)</p><p>9) Whether you usually place a bite block after endotracheal intubation?</p><p>a) Yes b) No</p><p>10) The method for fixing the ETT with adhesive tape:</p><p>a) Fixed the ETT in the shape of the letter X*</p><p>b) Fixed the ETT in other methods</p><p>*The shape of the letter X: using two pieces of adhesive tapes of appropriate length and width, where one piece of tape was attached to one side of the cheek, wrapped around the tube two circles, and subsequently cross-fixed on the same side of the cheek, and the other piece of tape was attached to the other side of the cheek, wrapped around the tube two circles, and then cross-fixed on the same side.</p><p>11) When placing a bite block, the method that you fixed the ETT was:</p><p>a) Fixed the bite block and ETT together</p><p>b) First fixed the ETT and then fixed the bite block with ETT</p><p>c) Fixed the ETT and bite block completely separately</p><p>d) Only fixed the ETT, not the bite block</p><p>The respondents who have experienced ETT displacement and the serious consequences</p><p>12) Did you experience the ETT displacement during your clinical anesthesia</p><p>a) Yes b) No</p><p>13) How many cases of ETT displacement you have experienced: _____</p><p>14) Did you experience serious consequences caused by the ETT displacement</p><p>a) Yes b) No</p><p>15) The serious consequence caused by the ETT displacement you have experienced:</p><p>a) Death b) Cardiac arrest c) Hypoxemia d) Atelectasis</p><p>e) Others</p><p>The factors influencing anesthesiologists to determine the method of ETT fixation.</p><p>16) Did you consider the influence of the surgical site and position on fixing the ETT?</p><p>a) Yes b) No</p><p>17) The material for fixing the ETT in patients who underwent head and neck surgery or in the prone position</p><p>a) The same as the material for fixing general ETT.</p><p>b) Reinforce with adhesive tape</p><p>c) Reinforce with a transparent film dressing.</p><p>d) Reinforce with other materials</p><p>18) Did you consider the influence of the age of the patient on fixing the ETT?</p><p>a) Yes b) No</p><p>19) The material for fixing the ETT in pediatric</p><p>a) The same as the material for fixing general ETT.</p><p>b) Reinforce with adhesive tape.</p><p>c) Reinforce with a transparent film dressing.</p><p>d) Reinforce with other materials</p><p>20) In your opinion, the primary cause of ETT displacement in patients in the supine position with except head and neck surgery:</p><p>a) Improperly fixed</p><p>b) Poor quality of fixation materials</p><p>c) A change in position</p><p>d) Staff mistakes</p><p>e) Excessive oral secretion</p></sec></body><back><ref-list><title>References</title><ref id="scirp.111628-ref1"><label>1</label><mixed-citation publication-type="other" xlink:type="simple">Sugiyama, K. and Yokoyama, K. 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