<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article  PUBLIC "-//NLM//DTD Journal Publishing DTD v3.0 20080202//EN" "http://dtd.nlm.nih.gov/publishing/3.0/journalpublishing3.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="3.0" xml:lang="en" article-type="research article"><front><journal-meta><journal-id journal-id-type="publisher-id">OJMSi</journal-id><journal-title-group><journal-title>Open Journal of Modelling and Simulation</journal-title></journal-title-group><issn pub-type="epub">2327-4018</issn><publisher><publisher-name>Scientific Research Publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.4236/ojmsi.2021.94021</article-id><article-id pub-id-type="publisher-id">OJMSi-111569</article-id><article-categories><subj-group subj-group-type="heading"><subject>Articles</subject></subj-group><subj-group subj-group-type="Discipline-v2"><subject>Physics&amp;Mathematics</subject></subj-group></article-categories><title-group><article-title>
 
 
  Generalized Power Akshaya Distribution and Its Applications
 
</article-title></title-group><contrib-group><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Ahmed</surname><given-names>T. Ramadan</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="corresp" rid="cor1"><sup>*</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Ahlam</surname><given-names>H. Tolba</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><xref ref-type="corresp" rid="cor1"><sup>*</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Beih</surname><given-names>S. El-Desouky</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref><xref ref-type="corresp" rid="cor1"><sup>*</sup></xref></contrib></contrib-group><aff id="aff1"><addr-line>Department of Basic Sciences, High Raya Institute, New Damietta, Egypt</addr-line></aff><aff id="aff2"><addr-line>Department of Mathematics, Faculty of Science, Mansoura University, Mansoura, Egypt</addr-line></aff><pub-date pub-type="epub"><day>27</day><month>08</month><year>2021</year></pub-date><volume>09</volume><issue>04</issue><fpage>323</fpage><lpage>338</lpage><history><date date-type="received"><day>30,</day>	<month>June</month>	<year>2021</year></date><date date-type="rev-recd"><day>27,</day>	<month>August</month>	<year>2021</year>	</date><date date-type="accepted"><day>30,</day>	<month>August</month>	<year>2021</year></date></history><permissions><copyright-statement>&#169; Copyright  2014 by authors and Scientific Research Publishing Inc. </copyright-statement><copyright-year>2014</copyright-year><license><license-p>This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/</license-p></license></permissions><abstract><p>
 
 
  In this paper, a new two-parameter distribution called generalized power
   Akshaya distribution extended from Akshaya distribution is introduced. This distribution is proposed to model lifetime data. Statistical properties like density, hazard, survival and moments are derived. Two parameters estimation is introduced using maximum likelihood and Bayesian techniques. Finally, an application of real data and a simulation study are introduced to illustrate the usefulness of the proposed distribution.
 
</p></abstract><kwd-group><kwd>Akshaya Distribution</kwd><kwd> Generalized Distributions</kwd><kwd> Moments</kwd><kwd> Estimation</kwd></kwd-group></article-meta></front><body><sec id="s1"><title>1. Introduction</title><p>The statistical analysis and modeling of lifetime data are necessary for many applied sciences like insurance, finance, bio-medical and engineering sciences. So, many lifetime distributions are introduced in the last era. Al-Kutubi et al. [<xref ref-type="bibr" rid="scirp.111569-ref1">1</xref>] presented the Properties and estimation methods of a new extended two-parameter distribution and its applications in medicine and geology. Also, Brooks and Steven [<xref ref-type="bibr" rid="scirp.111569-ref2">2</xref>] provided a comprehensive tutorial review about Markov chain Monte Carlo (MCMC) algorithms and discussed some implementation issues associated with MCMC methods. Eliwa et al. [<xref ref-type="bibr" rid="scirp.111569-ref3">3</xref>] proposed a new generator of distributions and some of its fundamental properties. Epstein et al. [<xref ref-type="bibr" rid="scirp.111569-ref4">4</xref>] discussed statistical problems which arise when the observations become available in an ordered manner. Also in 2013 Ghitany et al. [<xref ref-type="bibr" rid="scirp.111569-ref5">5</xref>] introduced the statistical properties of new two-parameter distribution called power Lindley mixed of Weibull and generalized gamma distributions. In addition, Ghitany et al. [<xref ref-type="bibr" rid="scirp.111569-ref6">6</xref>] showed that Lindley distribution is a better model than the exponential distribution. In 1980, Glaser [<xref ref-type="bibr" rid="scirp.111569-ref7">7</xref>] studied the sufficient conditions that ensure that a lifetime density has an increasing, decreasing or a bathtub-shaped failure rate. Measuring skewness and a quantile alternative for kurtosis are studied in [<xref ref-type="bibr" rid="scirp.111569-ref8">8</xref>] and [<xref ref-type="bibr" rid="scirp.111569-ref9">9</xref>] respectively. In 2011, Nadarajah et al. [<xref ref-type="bibr" rid="scirp.111569-ref10">10</xref>] introduced the generalized Lindley distribution and proved that it is better than gamma, lognormal, Weibull and exponential distributions with bathtub hazard rate. Okasha and Mustafa [<xref ref-type="bibr" rid="scirp.111569-ref11">11</xref>] used the E-Bayesian estimation for the Weibull distribution based on adaptive progressive hybrid censored competing risks. Rama Shanker [<xref ref-type="bibr" rid="scirp.111569-ref12">12</xref>] introduced a new one parameter Akash distribution which is a mixture of exponential (θ) and gamma (3, θ) distributions. Also, he introduced Akshaya distribution with one parameter [<xref ref-type="bibr" rid="scirp.111569-ref13">13</xref>] for modeling lifetime data which gave a better fit than the classical exponential and Lindley distributions. Shanker et al. [<xref ref-type="bibr" rid="scirp.111569-ref14">14</xref>] presented the relationships and comparative studies of Akash, Shanker, Lindley and exponential distributions and estimated their parameters. Besides that the previous articles talked about some lifetime distributions, other articles talked about parameters estimation methods. Finally, Smith et al. [<xref ref-type="bibr" rid="scirp.111569-ref15">15</xref>] developed and compared the maximum likelihood and Bayesian estimators for the three-parameter Weibull distribution.</p><p>According to Shanker [<xref ref-type="bibr" rid="scirp.111569-ref13">13</xref>], the probability density function (pdf) of Akshaya distribution is given by</p><p>f ( x ; θ ) = θ 4 θ 3 + 3 θ 2 + 6 θ + 6 ( 1 + x ) 3 e − θ x ,   x , θ &gt; 0 , (1)</p><p>the cumulative distribution function (CDF) is given by</p><p>F ( x ; θ ) = 1 − { 1 + θ 3 x 3 + 3 θ 2 ( θ + 1 ) x 2 + 3 θ ( θ 2 + 2 θ + 2 ) x θ 3 + 3 θ 2 + 6 θ + 6 } e − θ x ,   x , θ &gt; 0 , (2)</p><p>and the hazard rate function is given by</p><p>h ( x ; θ ) = θ 4 ( 1 + x ) 3 θ 3 x 3 + 3 θ 2 ( θ + 1 ) x 2 + 3 θ ( θ 2 + 2 θ + 2 ) x + ( θ 3 + 3 θ 2 + 6 θ + 6 ) ,   x , θ &gt; 0. (3)</p><p>The hazard rate function given in Equation (3) is increasing function of x and θ . However, Akshaya distribution is not suitable for many situations from a theoretical point of view. So, a more flexible extension of Akshaya distribution is introduced in this paper.</p><p>Ghitany et al. [<xref ref-type="bibr" rid="scirp.111569-ref5">5</xref>] used the transformation X = Y 1 α to generate a new distribution called power Lindley distribution. By using this transformation, a new generalized power Akshaya distribution can be introduced.</p><p>Let y = x α → x = y 1 α → d x = 1 α y 1 α − 1 d y</p><p>F ( y ) = F 0 ( x α ) , f ( y ) = α x α − 1 f 0 ( x α ) . (4)</p><p>The aim of this paper is to study some properties of the generalized power Akshaya distribution including the density and hazard functions as in Section 2. Section 3 studied some statistical properties like moments of the distribution, incomplete moments, mean residual lifetime and mean time to failure. Two methods of parameter estimation are given in Section 4. Application of two types of data, real data and simulation study are presented in Section 5 to show the flexleibility of the distribution.</p></sec><sec id="s2"><title>2. Generalized Power Akshaya Distribution</title>Some Basic Functions<p>According to Equations (1), (2) and (4), the cumulative distribution function (CDF) and the probability density function (pdf) of power Akshaya distribution are given respectively as</p><p>F ( x ; θ , α ) = 1 − { 1 + θ 3 x 3 α + 3 θ 2 ( θ + 1 ) x 2 α + 3 θ ( θ 2 + 2 θ + 2 ) x α θ 3 + 3 θ 2 + 6 θ + 6 } e − θ x α ,   x , θ , α &gt; 0 , (5)</p><p>f ( x ; θ , α ) = α x α − 1 θ 4 θ 3 + 3 θ 2 + 6 θ + 6 ( 1 + x α ) 3 e − θ x α ,   θ , α &gt; 0. (6)</p><p>Akshaya distribution function is obtained from Equation (5) when α = 1 .</p><p>From Equation (6), we can notice the behavior of f ( x ; θ , α ) at x = 0 and x = ∞ as the following</p><p>f ( 0 ) = ( ∞ ,   α &lt; 1 , θ 4 θ 3 + 3 θ 2 + 6 θ + 6 ,   α = 1 , 0 ,   α &gt; 1 ,     f ( ∞ ) = 0.</p><p>The following theorem shows that there are three shapes for the density function of the generalized power Akshaya distribution according to the values of the parameters θ and α .</p><p>Theorem 1. The density function of the generalized power Akshaya distribution given in Equation (6) is</p><p>(a) decreasing if 0 &lt; α ≤ 1 ,   θ ≥ η 1 ,</p><p>(b) uni-modal if α ≥ 1 ,</p><p>(c) decreasing-increasing-decreasing if 0 &lt; α ≤ 1 ,   0 &lt; θ &lt; η 1 ,</p><p>Where η 1 = 1 + 2 α − 2 3 α ( 1 − α ) α .</p><p>Proof. The first derivative of f ( x ; θ , α ) of generalized power Akshaya distribution is</p><p>f ′ ( x ) = α θ 4 θ 3 + 3 θ 2 + 6 θ + 6 x α − 2 ( 1 + x α ) 2 e − θ x α Ψ 1 ( x α ) , x &gt; 0 ,</p><p>where Ψ 1 ( y ) = a 1 y 2 + b 1 y + c 1 ,   y = x α &gt; 0 , and a 1 = − θ α ,   b 1 = 4 α − 1 − θ α ,   c 1 = α − 1 .</p><p>It is obvious that f ′ ( x ) and Ψ 1 ( y ) have the same sign. The function Ψ 1 ( y ) is:</p><p>(a) decreasing if Ψ 1 has one or no real roots,</p><p>b 1 2 − 4 a 1 c 1 ≤ 0 , then ( 4 α − 1 − θ α ) 2 + 4 θ α ( α − 1 ) ≤ 0</p><p>which implies to 0 &lt; α ≤ 1 ,   θ ≥ 1 + 2 α − 2 3 α ( 1 − α ) α ,</p><p>with Ψ 1 ( 0 ) = c 1 , Ψ 1 ( ∞ ) = − ∞ .</p><p>(b) uni-modal with maximum value at the point y 1 = − b 1 2 a 1 if c 1 &gt; 0 , i.e. α &gt; 1 .</p><p>(c) combining stated conditions in (a) and (b) we note that the function Ψ 1 ( y ) changes its sign from negative to positive to negative and this completes the proof. <inline-formula><inline-graphic xlink:href="/html.scirp.org/file/1-2860213x38.png" xlink:type="simple"/></inline-formula></p><p><xref ref-type="fig" rid="fig1">Figure 1</xref> and <xref ref-type="fig" rid="fig2">Figure 2</xref> show the CDF and pdf functions of generalized power Akshaya distribution for different values of θ , α .</p><p>The survival function, S ( x ) and the hazard function, H ( x ) of generalized power Akshaya distribution, are given respectively as</p><p>S ( x ; θ , α ) = 1 − F ( x ; θ , α ) = { 1 + θ 3 x 3 α + 3 θ 2 ( θ + 1 ) x 2 α + 3 θ ( θ 2 + 2 θ + 2 ) x α θ 3 + 3 θ 2 + 6 θ + 6 } e − θ x α ,   x , θ , α &gt; 0 , (7)</p><p>H ( x ; θ , α ) = f ( x ; θ , α ) S ( x ; θ , α ) = α θ 4 x α − 1 ( 1 + x α ) 3 θ 3 ( 1 + x 3 α ) + 3 θ 2 ( 1 + ( θ + 1 ) x 2 α ) + 3 θ ( 2 + ( θ 2 + 2 θ + 2 ) x α ) + 6 ,   x , θ , α &gt; 0. (8)</p><p>From Equation (8), we can notice that the behavior of H ( x ; θ , α ) at x = 0 is the same as the behavior of f ( x ; θ , α ) at x = 0 , so that</p><p>H ( 0 ) = ( ∞ ,   α &lt; 1 , θ 4 θ 3 + 3 θ 2 + 6 θ + 6 ,   α = 1 , 0 ,   α &gt; 1 ,</p><p>and</p><p>H ( ∞ ) = ( 0 ,     α &lt; 1 , θ ,     α = 1 , ∞ ,     α &gt; 1.</p><p>The analytic analysis of the hazard function shape is very complicated, so according to [<xref ref-type="bibr" rid="scirp.111569-ref7">7</xref>], Glaser’s theorem is applied here. Now,</p><p>η ( x ) = − f ′ ( x ) f ( x ) = α θ x 2 α + x α ( α ( θ − 4 ) + 1 ) + 1 − α x ( 1 + x α ) ,</p><p>η ′ ( x ) = Ψ 2 ( x ) x 2 ( 1 + x α ) 2 ,</p><p>where</p><p>Ψ 2 ( x ) = α θ ( α − 1 ) x 3 α + x 2 α ( 2 θ α 2 − 2 α ( θ − 2 ) − 1 )       + x α ( α − 1 ) ( α ( θ − 3 ) + 2 ) + α − 1.</p><p>Consequently, the hazard function, H ( x ) , and the function Ψ 2 ( x ) have the same sign and the function Ψ 2 ( x ) is:</p><p>(a) increasing if α ≥ 1 ,   θ &gt; 0 ,</p><p>(b) decreasing if 0 &lt; α ≤ 0.25 ,   θ &gt; 0 ,</p><p>(c) decreasing-increasing-decreasing if 0.25 &lt; α &lt; 1 ,   θ &gt; 0 .</p><p><xref ref-type="fig" rid="fig3">Figure 3</xref> and <xref ref-type="fig" rid="fig4">Figure 4</xref> show the survival and hazard functions of generalized power Akshaya distribution for different values of θ , α .</p></sec><sec id="s3"><title>3. Statistical Properties</title><sec id="s3_1"><title>3.1. Moments</title><p>In this subsection, the first four moments about zero and about mean and the incomplete moments of generalized power Akshaya distribution are derived. The general form of the r<sup>th</sup> moment about zero is given by</p><p>μ ′ r = E ( x r ) = ∫ 0 ∞     x r f ( x ; θ , α ) d x . (9)</p><p>According to Equation (9) and using Equation (6), the r<sup>th</sup> moment about zero of generalized power Akshaya distribution is given by</p><p>μ ′ r = c α ∫ 0 ∞     x r x α − 1 ( 1 + x α ) 3 e − θ x α d x , c = θ 4 θ 3 + 3 θ 2 + 6 θ + 6 .</p><p>Let t = θ x α → x = ( t θ ) 1 α → d x = 1 θ α ( t θ ) 1 α − 1 d t ,</p><p>μ ′ r = c α ∫ 0 ∞ ( t θ ) r α ( t θ ) 1 − 1 α ( 1 + ( t θ ) ) 3 e − θ ( t θ ) 1 θ α ( t θ ) 1 α − 1 d t .</p><p>Finally, the r<sup>th</sup> moment about zero of generalized power Akshaya distribution is given by</p><p>μ ′ r = r θ − r α ( r 3 + 3 r 2 α ( 2 + θ ) + r α 2 ( 11 + 3 θ ( 3 + θ ) ) + α 3 ( 6 + θ ( 6 + θ ( 3 + θ ) ) ) ) Γ ( r α ) α 4 ( 6 + θ ( 6 + θ ( 3 + θ ) ) ) . (10)</p><p>Substituting in Equation (10) with r = 1 , 2 , 3 and 4 we get</p><p>μ ′ 1 = θ − 1 α ( 1 + α ( 3 ( 2 + θ ) + α ( 11 + 3 θ ( 3 + θ ) + α ( 6 + θ ( 6 + θ ( 3 + θ ) ) ) ) ) ) Γ ( 1 α ) α 4 ( 6 + θ ( 6 + θ ( 3 + θ ) ) ) ,</p><p>μ ′ 2 = 2 θ − 2 α ( 8 + α ( 12 ( 2 + θ ) + α ( 22 + 6 θ ( 3 + θ ) + α ( 6 + θ ( 6 + θ ( 3 + θ ) ) ) ) ) ) Γ ( 2 α ) α 4 ( 6 + θ ( 6 + θ ( 3 + θ ) ) ) ,</p><p>μ ′ 3 = 3 θ − 3 α ( 27 + α ( 27 ( 2 + θ ) + α ( 33 + 9 θ ( 3 + θ ) + α ( 6 + θ ( 6 + θ ( 3 + θ ) ) ) ) ) ) Γ ( 3 α ) α 4 ( 6 + θ ( 6 + θ ( 3 + θ ) ) ) ,</p><p>and</p><p>μ ′ 4 = 4 θ − 4 α ( 64 + 48 α ( 2 + θ ) + 4 α 2 ( 11 + 3 θ ( 3 + θ ) ) + α 3 ( 6 + θ ( 6 + θ ( 3 + θ ) ) ) ) Γ ( 4 α ) α 4 ( 6 + θ ( 6 + θ ( 3 + θ ) ) ) .</p><p>Also, the first four moments about mean can be deduced from moments about zero as follows</p><p>μ 1 = 0 ,</p><p>μ 2 = μ ′ 2 − ( μ ′ 1 ) 2 ,</p><p>μ 3 = μ ′ 3 − 3 μ ′ 2 μ ′ 1 + 2 ( μ ′ 1 ) 3 and</p><p>μ 4 = μ ′ 4 − 4 μ ′ 3 μ ′ 1 + 6 μ ′ 2 ( μ ′ 1 ) 2 − 3 ( μ ′ 1 ) 4 .</p></sec><sec id="s3_2"><title>3.2. Incomplete Moments and Related Measures</title><p>In this subsection, we introduce the r<sup>th</sup> incomplete moment, m r ( y ) and some related measures like mean deviation about mean and median and Bonferroni and Lorenz curves.</p><sec id="s3_2_1"><title>3.2.1. Incomplete Moments</title><p>The r<sup>th</sup> incomplete moments is given by</p><p>m r ( y ) = ∫ 0 y     x r f ( x ) d x = y r ( θ y α ) − r α 6 + 6 θ + 3 θ 2 + θ 3 ( θ 3 Γ ( 1 + r α ) + 3 θ 2 Γ ( 2 + r α ) + 3 θ   Γ ( 3 + r α )       + Γ ( 4 + r α ) − θ 3 Γ ( 1 + r α , θ y α ) − 3 θ 2 Γ ( 2 + r α , θ y α )       − 3 θ   Γ ( 3 + r α , θ y α ) − Γ ( 4 + r α , θ y α ) ) . (11)</p></sec><sec id="s3_2_2"><title>3.2.2. Mean Deviation about Mean and Median</title><p>Mean deviation about mean of a parameter X~ power Akshaya distribution, δ 1 ( x ) can be given as follows</p><p>δ 1 ( x ) = ∫ 0 ∞ | x − μ ′ 1 | f ( x ) d x = 2 μ ′ 1 F ( μ ′ 1 ) − 2 ∫ 0 μ ′ 1     x f ( x ) d x = 2 μ ′ 1 F ( μ ′ 1 ) − 2 m 1 ( μ ′ 1 ) , (12)</p><p>where m 1 ( . ) is the incomplete moment given in Equation (11) when r = 1 .</p><p>The mean deviation about median (M) of a parameter X~ power Akshaya distribution, δ 2 ( x ) can be given as follows</p><p>δ 2 ( x ) = ∫ 0 ∞ | x − M | f ( x ) d x = μ ′ 1 − 2 ∫ 0 M     x f ( x ) d x = μ ′ 1 − 2 m 1 ( M ) . (13)</p></sec><sec id="s3_2_3"><title>3.2.3. Bonferroni and Lorenz Curves</title><p>The Bonferroni and Lorenz curves have large applications in economy to study income and poverty and other fields. Bonferroni and Lorenz curves are defined as</p><p>B ( p ) = 1 p μ ∫ 0 q     x f ( x ) d x = m 1 ( q ) p μ , (14)</p><p>L ( p ) = 1 μ ∫ 0 q     x f ( x ) d x = m 1 ( q ) μ . (15)</p></sec></sec><sec id="s3_3"><title>3.3. Quantile Function, Bowley Skewness and Moors Kurtosis</title><p>For any q ∈ ( 0,1 ) , the q<sup>th</sup> quantile function (Q(q)) is the solution of F ( Q ( q ) ) = q ; Q ( q ) &gt; 0 , in other words, q = F − 1 ( x ; θ , α ) .</p><p>It’s obvious if we set q = 0.5 we get the median (M). Bowley skewness [<xref ref-type="bibr" rid="scirp.111569-ref8">8</xref>] and Moors kurtosis [<xref ref-type="bibr" rid="scirp.111569-ref9">9</xref>] can be obtained as</p><p>Bowleyskewness = Q ( 3 4 ) + Q ( 1 4 ) − 2 Q ( 1 2 ) Q ( 3 4 ) − Q ( 1 4 ) ,</p><p>and</p><p>Moorskurtosis = Q ( 3 8 ) − Q ( 1 8 ) + Q ( 7 8 ) − Q ( 5 8 ) Q ( 6 8 ) − Q ( 2 8 ) .</p></sec><sec id="s3_4"><title>3.4. Mean Residual Lifetime</title><p>Mean residual lifetime (m) is a reliability term based on lifetime of the product. It is a way to give a numeric value based on the residual lifetime of the product. Mean residual lifetime (m) can be given as follows</p><p>m ( x ) = E [ X − x / X &gt; x ] = 1 1 − F ( x ) ∫ x ∞ ( 1 − F ( t ) ) d t = [ e θ x α θ − 1 α ( θ x α ) − 1 α ( − x θ 1 α + ( θ x α ) 1 α ) ( 1 + 3 α ( 2 + θ ) + α 2 ( 11 + 9 θ + 3 θ 2 )       + α 3 ( 6 + 6 θ + 3 θ 2 + θ 3 ) ) Γ ( 1 α ) + x α 3 θ 1 α ( 3 ( 2 + 2 θ + θ 2 ) Γ ( 1 + 1 α , θ x α )       + 3 ( 1 + θ ) Γ ( 2 + 1 α , θ x α ) + Γ ( 3 + 1 α , θ x α ) + 6 θ   Γ ( 1 α , θ x α )       + 3 θ 2 Γ ( 1 α , θ x α ) + θ 3 Γ ( 1 α , θ x α ) ) ] / [ α 4 ( θ x α ( 6 + 3 θ ( 2 + x α )       + θ 2 ( 3 + 3 x α + x 2 α ) ) + e θ x α ( 6 + 6 θ + 3 θ 2 + θ 3 ) ) ] . (16)</p></sec><sec id="s3_5"><title>3.5. Mean Time to Failure</title><p>Mean time to failure (MTTF) is also a reliability term based on lifetime of the product. It gives a numeric value based on a compilation of data to quantify a failure rate of the product. MTTF can be given as follows</p><p>MTTF = θ − 1 α ( 1 + α ( 3 ( 2 + θ ) + α ( 11 + 3 θ ( 3 + θ ) + α ( 6 + θ ( 6 + θ ( 3 + θ ) ) ) ) ) ) Γ ( 1 α ) α 4 ( 6 + 6 θ + 3 θ 2 + θ 3 ) . (17)</p></sec></sec><sec id="s4"><title>4. Parameters Estimation</title><p>In this section, two techniques including maximum likelihood estimation (MLE) method and Bayesian estimation method are used to estimate the parameters of generalized power Akshaya distribution.</p><sec id="s4_1"><title>4.1. Maximum Likelihood Estimation Method</title><p>Let ( x 1 , x 2 , ⋯ , x n ) be a random sample from generalized power Akshaya distribution, then the likelihood estimation function, L can be given as follows</p><p>L = ∏ i = 1 n     f ( x ; θ , α ) = α n θ 4 n ( θ 3 + 3 θ 2 + 6 θ + 6 ) n e − θ ∑ i = 1 n x i α ∏ i = 1 n     x i α − 1 ( 1 + x i α ) 3 , (18)</p><p>and the natural log likelihood function is given by</p><p>ln ( L ) = n { ln ( α ) + 4 ln ( θ ) − ln ( θ 3 + 3 θ 2 + 6 θ + 6 ) }       − θ ∑ i = 1 n     x i α + ∑ i = 1 n { ( α − 1 ) ln ( x i ) + 3 ln ( 1 + x i α ) } . (19)</p><p>The first derivatives of the natural log likelihood function with respect to θ , α are given by</p><p>∂ ∂ θ ln ( L ) = 4 n θ − 3 θ 2 + 6 θ + 6 θ 3 + 3 θ 2 + 6 θ + 6 − ∑ i = 1 n     x i α , (20)</p><p>∂ ∂ α ln ( L ) = n α − θ ∑ i = 1 n     x i α ln ( x i ) + ∑ i = 1 n { ln ( x i ) ( 1 + 3 x i α 1 + x i α ) } . (21)</p><p>Equations (20) and (21) have no analytic closed form when equating by zero, so numerical methods are used to give solutions. The second derivatives of the natural log likelihood function with respect to θ , α can be given by</p><p>∂ 2 ∂ θ 2 ln ( L ) = − 4 n θ 2 − 6 ( θ + 1 ) ( θ 3 + 3 θ 2 + 6 θ + 6 ) − ( 3 θ 2 + 6 θ + 6 ) 2 ( θ 3 + 3 θ 2 + 6 θ + 6 ) 2 , (22)</p><p>∂ 2 ∂ θ ∂ α ln ( L ) = ∑ i = 1 n     x α ln ( x i ) , (23)</p><p>∂ 2 ∂ α ∂ θ ln ( L ) = ∑ i = 1 n     x α ln ( x i ) , (24)</p><p>∂ 2 ∂ α 2 ln ( L ) = − n α 2 − θ ∑ i = 1 n     x i α ( ln ( x i ) ) 2 + ∑ i = 1 n { ln ( x i ) ( 1 + 3 x i α ln ( x i ) ( 1 + x i α ) 2 ) } . (25)</p><p>The ( 1 − ζ ) 100 % confidence interval for the parameters θ and α can be written as</p><p>( θ ^ L , θ ^ U ) = θ ^ ∓ z 1 − ζ 2 var ( θ ^ ) ,   ( α ^ L , α ^ U ) = α ^ ∓ z 1 − ζ 2 var ( α ^ ) ,</p><p>where θ ^ and α ^ are the maximum likelihood estimates of θ and α , z 1 − ζ 2 is the percentile of the standard normal distribution and var ( θ ^ ) , var ( α ^ ) are the asymptotic variances of maximum likelihood estimates calculated using the inverse of the information matrix as follows</p><p>F − 1 = [ − ∂ 2 ∂ θ 2 ln L − ∂ 2 ∂ θ ∂ α ln L − ∂ 2 ∂ α 2 ln L − ∂ 2 ∂ α ∂ θ ln L ] − 1 = [ var ( θ ^ ) cov ( θ ^ , α ^ ) cov ( α ^ , θ ^ ) var ( α ^ ) ] − 1 . (26)</p></sec><sec id="s4_2"><title>4.2. Bayesian Estimation Method</title><p>In this subsection, Bayesian estimation (BE) approach is used to estimate the parameters θ and α which are assumed to be independent and follow gamma prior distribution with parameters a and b.</p><p>The gamma prior density function has the form</p><p>g ( u ; a , b ) = b a Γ ( a ) u a − 1 e − u b ,   u , a , b &gt; 0. (27)</p><p>Then, the joint prior density of θ and α is given by</p><p>g ( θ , α ) = ∏ i = 1 n     g ( θ ) g ( α ) ∝ ( θ α ) a − 1 e − ( θ + α ) b . (28)</p><p>The joint posterior distribution function according to Bayesian procedure is given by</p><p>g ( θ , α | x _ ) = g ( θ , α ) L ( x _ ) ∫ g ( θ , α ) L ( x _ ) ∝ g ( θ , α ) L ( x _ ) . (29)</p><p>Substituting from Equations (28) and (18) into Equation (29) we get</p><p>g ( θ , α | x _ ) ∝ ( θ α ) a − 1 e − ( θ ( ∑ i = 1 n x i α + b ) + α b ) ∏ i = 1 n     x i α − 1 ( 1 + x i α ) 3 . (30)</p><p>Markov Chain Monte Carlo method (MCMC) [<xref ref-type="bibr" rid="scirp.111569-ref2">2</xref>] is used to summarize the posterior distribution numerically without calculating the normalized constant.</p></sec></sec><sec id="s5"><title>5. Applications and Goodness of Fit</title><p>In this section, the goodness of fit of generalized power Akshaya distribution to real lifetime data is proposed and compared with some one parameter and two parameters distributions.</p><p>The data set represents the waiting times (in minutes) before service of 100 bank customers and analyzed and examined by Ghitany et al. [<xref ref-type="bibr" rid="scirp.111569-ref6">6</xref>] for fitting the lindley distribution. The data set is given as follows</p><p>Some statistics like, − 2 ln ( L ) , Akaike Information Criterion (AIC), Kolmogorov-Samirnov Statistics (K-S) and Bayesian estimate (BE) for this data are computed to compare between various lifetime distributions. These statistics are shown in <xref ref-type="table" rid="table1">Table 1</xref>.</p><p>The best distribution fitting the data is the distribution with least − 2 ln ( L ) , AIC, and least K-S statistics and <xref ref-type="table" rid="table1">Table 1</xref> showed that power Akshaya distribution is better than others. The inverse of the information matrix of power Akshaya distribution using the estimated parameters, θ ^ and α ^ according to the MLE method can be given by</p><p>F − 1 = [ var ( θ ^ ) cov ( θ ^ , α ^ ) cov ( α ^ , θ ^ ) var ( α ^ ) ] − 1 = [ 0.004 − v e − v e 0.002 ] − 1 , (31)</p><p>and the 95% confidence interval for the parameters θ and α can be given as</p><table-wrap id="table1" ><label><xref ref-type="table" rid="table1">Table 1</xref></label><caption><title> The MLE, BE estimates, − 2 ln ( L ) , AIC, K-S and P-value statistics</title></caption><table><tbody><thead><tr><th align="center" valign="middle"  rowspan="2"  >Distributions</th><th align="center" valign="middle"  colspan="2"  >MLE</th><th align="center" valign="middle"  colspan="2"  >BE</th><th align="center" valign="middle"  rowspan="2"  >− 2 ln ( L )</th><th align="center" valign="middle"  rowspan="2"  >AIC</th><th align="center" valign="middle"  rowspan="2"  >K-S</th><th align="center" valign="middle"  rowspan="2"  >P-value</th></tr></thead><tr><td align="center" valign="middle" >θ ^</td><td align="center" valign="middle" >α ^</td><td align="center" valign="middle" >θ ^</td><td align="center" valign="middle" >α ^</td></tr><tr><td align="center" valign="middle" >power Akshaya</td><td align="center" valign="middle" >0.556</td><td align="center" valign="middle" >0.814</td><td align="center" valign="middle" >0.559</td><td align="center" valign="middle" >0.813</td><td align="center" valign="middle" >635.73</td><td align="center" valign="middle" >639.73</td><td align="center" valign="middle" >0.04</td><td align="center" valign="middle" >0.9876</td></tr><tr><td align="center" valign="middle" >power Lindley</td><td align="center" valign="middle" >0.153</td><td align="center" valign="middle" >1.083</td><td align="center" valign="middle" >0.160</td><td align="center" valign="middle" >1.072</td><td align="center" valign="middle" >636.64</td><td align="center" valign="middle" >640.64</td><td align="center" valign="middle" >0.50</td><td align="center" valign="middle" >2.2e<sup>−</sup><sup>16</sup></td></tr><tr><td align="center" valign="middle" >Akshaya</td><td align="center" valign="middle" >0.368</td><td align="center" valign="middle" >-</td><td align="center" valign="middle" >0.368</td><td align="center" valign="middle" >-</td><td align="center" valign="middle" >649.72</td><td align="center" valign="middle" >651.72</td><td align="center" valign="middle" >0.13</td><td align="center" valign="middle" >0.074</td></tr><tr><td align="center" valign="middle" >Akash</td><td align="center" valign="middle" >0.295</td><td align="center" valign="middle" >-</td><td align="center" valign="middle" >0.296</td><td align="center" valign="middle" >-</td><td align="center" valign="middle" >641.93</td><td align="center" valign="middle" >643.91</td><td align="center" valign="middle" >0.10</td><td align="center" valign="middle" >2.2e<sup>−</sup><sup>16</sup></td></tr><tr><td align="center" valign="middle" >Lindley</td><td align="center" valign="middle" >0.187</td><td align="center" valign="middle" >-</td><td align="center" valign="middle" >0.187</td><td align="center" valign="middle" >-</td><td align="center" valign="middle" >638.07</td><td align="center" valign="middle" >640.07</td><td align="center" valign="middle" >0.058</td><td align="center" valign="middle" >2.2e<sup>−</sup><sup>16</sup></td></tr><tr><td align="center" valign="middle" >Exponential</td><td align="center" valign="middle" >0.101</td><td align="center" valign="middle" >-</td><td align="center" valign="middle" >0.102</td><td align="center" valign="middle" >-</td><td align="center" valign="middle" >658.04</td><td align="center" valign="middle" >660.04</td><td align="center" valign="middle" >0.163</td><td align="center" valign="middle" >2.2e<sup>−</sup><sup>16</sup></td></tr></tbody></table></table-wrap><p>( θ ^ L , θ ^ U ) = ( 0.431 , 0.680 ) ,   ( α ^ L , α ^ U ) = ( 0.719 , 0.908 ) .</p></sec><sec id="s6"><title>6. Simulation Study</title><p>In this section, random data of generalized power Akshaya is generated using the inverse of cumulative distribution function numerically. Mathematica program is used to generate different samples of the distribution when the size is n = 20, 50, 70, 100, and 150. The experiment is repeated 5000 times with initial values θ = 1.5 and α = 0.5 . Five quantities are examined in this study</p><p>(a) Mean of the estimated values (ME) of ν ^ , ν ^ = θ ^ , α ^ which equals 1 5000 ∑ i = 1 5000     ν ^ i .</p><p>(b) Average bias of the MLE (AB) of ν ^ which equals 1 5000 ∑ i = 1 5000 ( ν ^ i − ν ) .</p><p>(c) The mean squared error (MSE) of the MLE of ν ^ which equals 1 5000 ∑ i = 1 5000 ( ν ^ i − ν ) 2 .</p><p>(d) Average width (AW) of 95% confidence intervals of parameter ν = θ , α which equals ( ν ^ + 1.96 ν ) − ( ν ^ − 1.96 ν ) .</p><p>(e) Coverage probability (CP) of 95% confidence intervals of parameter ν = θ , α , i.e. the percentage of intervals that contain true values of the parameter ν .</p><p><xref ref-type="table" rid="table2">Table 2</xref> shows that</p><p>&#183; The absolute value of the average bias | A B | for the parameters θ , α decreases as the sample size (n) increases.</p><p>&#183; The mean squared error (MSE) for the parameters θ and α decreases as the sample size (n) increases.</p><p>&#183; The average width (AW) for the parameters θ and α decreases as the sample size (n) increases.</p><p><xref ref-type="fig" rid="fig5">Figure 5</xref> shows the scaled TTT-transform, and it found increasing, and the empirical pdf for the simulated data. <xref ref-type="fig" rid="fig6">Figure 6</xref> shows the Q-Q plots for the simulated data and distributions mentioned in <xref ref-type="table" rid="table1">Table 1</xref> and it shows that the generalized power Akshaya distribution is the best fit for the data. <xref ref-type="fig" rid="fig7">Figure 7</xref> shows the Kaplan Meier curve for the simulated data and the survival functions of the</p><table-wrap id="table2" ><label><xref ref-type="table" rid="table2">Table 2</xref></label><caption><title> Some measures of the simulated data for various sample sizes</title></caption><table><tbody><thead><tr><th align="center" valign="middle"  rowspan="2"  >n</th><th align="center" valign="middle"  colspan="5"  >θ</th><th align="center" valign="middle"  colspan="5"  >α</th></tr></thead><tr><td align="center" valign="middle" >ME</td><td align="center" valign="middle" >AB</td><td align="center" valign="middle" >MSE</td><td align="center" valign="middle" >AW</td><td align="center" valign="middle" >CP</td><td align="center" valign="middle" >ME</td><td align="center" valign="middle" >AB</td><td align="center" valign="middle" >MSE</td><td align="center" valign="middle" >AW</td><td align="center" valign="middle" >CP</td></tr><tr><td align="center" valign="middle" >20</td><td align="center" valign="middle" >1.478</td><td align="center" valign="middle" >−0.022</td><td align="center" valign="middle" >0.053</td><td align="center" valign="middle" >0.881</td><td align="center" valign="middle" >0.943</td><td align="center" valign="middle" >0.532</td><td align="center" valign="middle" >0.032</td><td align="center" valign="middle" >0.009</td><td align="center" valign="middle" >0.320</td><td align="center" valign="middle" >0.946</td></tr><tr><td align="center" valign="middle" >50</td><td align="center" valign="middle" >1.478</td><td align="center" valign="middle" >−0.022</td><td align="center" valign="middle" >0.020</td><td align="center" valign="middle" >0.556</td><td align="center" valign="middle" >0.941</td><td align="center" valign="middle" >0.514</td><td align="center" valign="middle" >0.014</td><td align="center" valign="middle" >0.003</td><td align="center" valign="middle" >0.195</td><td align="center" valign="middle" >0.953</td></tr><tr><td align="center" valign="middle" >70</td><td align="center" valign="middle" >1.487</td><td align="center" valign="middle" >−0.013</td><td align="center" valign="middle" >0.014</td><td align="center" valign="middle" >0.471</td><td align="center" valign="middle" >0.951</td><td align="center" valign="middle" >0.511</td><td align="center" valign="middle" >0.011</td><td align="center" valign="middle" >0.002</td><td align="center" valign="middle" >0.165</td><td align="center" valign="middle" >0.955</td></tr><tr><td align="center" valign="middle" >100</td><td align="center" valign="middle" >1.487</td><td align="center" valign="middle" >−0.013</td><td align="center" valign="middle" >0.009</td><td align="center" valign="middle" >0.394</td><td align="center" valign="middle" >0.955</td><td align="center" valign="middle" >0.510</td><td align="center" valign="middle" >0.010</td><td align="center" valign="middle" >0.001</td><td align="center" valign="middle" >0.137</td><td align="center" valign="middle" >0.958</td></tr><tr><td align="center" valign="middle" >150</td><td align="center" valign="middle" >1.488</td><td align="center" valign="middle" >−0.012</td><td align="center" valign="middle" >0.007</td><td align="center" valign="middle" >0.322</td><td align="center" valign="middle" >0.951</td><td align="center" valign="middle" >0.508</td><td align="center" valign="middle" >0.008</td><td align="center" valign="middle" >0.001</td><td align="center" valign="middle" >0.112</td><td align="center" valign="middle" >0.946</td></tr></tbody></table></table-wrap><table-wrap id="table3" ><label><xref ref-type="table" rid="table3">Table 3</xref></label><caption><title> Posterior summaries for the simulated data</title></caption><table><tbody><thead><tr><th align="center" valign="middle" >Prior</th><th align="center" valign="middle" >Parameters</th><th align="center" valign="middle" >Mean</th><th align="center" valign="middle" >SD</th><th align="center" valign="middle" >MC Error</th><th align="center" valign="middle" >2.5%</th><th align="center" valign="middle" >Median</th><th align="center" valign="middle" >97.5%</th></tr></thead><tr><td align="center" valign="middle" >Gamma</td><td align="center" valign="middle" >α</td><td align="center" valign="middle" >0.8129</td><td align="center" valign="middle" >0.05851</td><td align="center" valign="middle" >0.002007</td><td align="center" valign="middle" >0.7201</td><td align="center" valign="middle" >0.8103</td><td align="center" valign="middle" >0.9091</td></tr><tr><td align="center" valign="middle" >Gamma</td><td align="center" valign="middle" >θ</td><td align="center" valign="middle" >0.559</td><td align="center" valign="middle" >0.06751</td><td align="center" valign="middle" >0.001758</td><td align="center" valign="middle" >0.4408</td><td align="center" valign="middle" >0.5589</td><td align="center" valign="middle" >0.6887</td></tr></tbody></table></table-wrap><p>distributions mentioned in <xref ref-type="table" rid="table1">Table 1</xref> and also shows that the generalized power Akshaya distribution is the best fit for the data.</p><p><xref ref-type="table" rid="table3">Table 3</xref> shows a summary of some measures for the joint posterior distribution for the simulated data. <xref ref-type="fig" rid="fig8">Figure 8</xref> and <xref ref-type="fig" rid="fig9">Figure 9</xref> show the density and trace plot of parameters θ and α to assess the convergence visually.</p></sec><sec id="s7"><title>7. Conclusion</title><p>A new two parameters lifetime distribution named generalized power Akshaya distribution has been introduced for modeling lifetime data. Some statistical properties such as cumulative distribution, density, survival, hazard and moments functions. Also, maximum likelihood and Bayesian techniques are used to estimate distribution parameters. The goodness of fit using − 2 ln ( L ) , Akaike Information Criterion (AIC), Kolmogorov-Samirnov Statistics (K-S) and P-value for real lifetime data have been presented to show its applicability overpower Lindley, Akshaya, Akash, Lindley and exponential distributions. Finally, a simulation study is carried out to show the mean of the estimated values. The average bias and mean square error of the maximum likelihood estimators of the model parameters are discussed. In addition, the coverage probability and average width of the confidence intervals for the parameters are calculated.</p></sec><sec id="s8"><title>Conflicts of Interest</title><p>The authors declare no conflicts of interest regarding the publication of this paper.</p></sec><sec id="s9"><title>Cite this paper</title><p>Ramadan, A.T., Tolba, A.H. and El-Desouky, B.S. (2021) Generalized Power Akshaya Distribution and Its Applications. Open Journal of Modelling and Simulation, 9, 323-338. https://doi.org/10.4236/ojmsi.2021.94021</p></sec></body><back><ref-list><title>References</title><ref id="scirp.111569-ref1"><label>1</label><mixed-citation publication-type="other" xlink:type="simple">Al-Mofleh, H., Afify, A.Z. and Ibrahim, N.A. (2020) A New Extended Two-Parameter Distribution: Properties, Estimation Methods, and Applications in Medicine and Geology. Mathematics, 8, 15-78. https://doi.org/10.3390/math8091578</mixed-citation></ref><ref id="scirp.111569-ref2"><label>2</label><mixed-citation publication-type="other" xlink:type="simple">Brooks, S. (1998) Markov Chain Monte Carlo Method and Its Application. Journal of the Royal Statistical Society: Series D (the Statistician), 47, 69-100. https://doi.org/10.1111/1467-9884.00117</mixed-citation></ref><ref id="scirp.111569-ref3"><label>3</label><mixed-citation publication-type="other" xlink:type="simple">Eliwa, M.S., El-Morshedy, M. and Ali, S. (2020) Exponentiated Odd Chen-G Family of Distributions: Statistical Properties, Bayesian and Non-Bayesian Estimation with Applications. Journal of Applied Statistics, 2, 1-27. https://doi.org/10.1080/02664763.2020.1783520</mixed-citation></ref><ref id="scirp.111569-ref4"><label>4</label><mixed-citation publication-type="other" xlink:type="simple">Epstein, B. and Sobel, M. (1953) Life Testing. Journal of the American Statistical Association, 48, 486-502. https://doi.org/10.1080/01621459.1953.10483488</mixed-citation></ref><ref id="scirp.111569-ref5"><label>5</label><mixed-citation publication-type="other" xlink:type="simple">Ghitany, M.E., Al-Mutairi, D.K., Balakrishnan, N. and Al-Enezi, L.J. (2013) Power Lindley Distribution and Associated Inference. Computational Statistics &amp; Data Analysis, 64, 20-33. https://doi.org/10.1016/j.csda.2013.02.026</mixed-citation></ref><ref id="scirp.111569-ref6"><label>6</label><mixed-citation publication-type="other" xlink:type="simple">Ghitany, M.E., Atieh, B. and Nadarajah, S. (2008) Lindley Distribution and Its Application. Mathematics and Computers in Simulation, 78, 493-506. https://doi.org/10.1016/j.matcom.2007.06.007</mixed-citation></ref><ref id="scirp.111569-ref7"><label>7</label><mixed-citation publication-type="other" xlink:type="simple">Glaser, R.E. (1980) Bathtub and Related Failure Rate Characterizations. Journal of the American Statistical Association, 75, 667-672. https://doi.org/10.1080/01621459.1980.10477530</mixed-citation></ref><ref id="scirp.111569-ref8"><label>8</label><mixed-citation publication-type="other" xlink:type="simple">Groeneveld, R.A. and Meeden, G. (1984) Measuring Skewness and Kurtosis. Journal of the Royal Statistical Society: Series D (The Statistician), 33, 391-399.</mixed-citation></ref><ref id="scirp.111569-ref9"><label>9</label><mixed-citation publication-type="other" xlink:type="simple">Moors, J.J.A. (1988) A Quantile Alternative for Kurtosis. Journal of the Royal Statistical Society: Series D (The Statistician), 37, 25-23. https://doi.org/10.2307/2348376</mixed-citation></ref><ref id="scirp.111569-ref10"><label>10</label><mixed-citation publication-type="other" xlink:type="simple">Nadarajah, S., Bakouch, H.S. and Tahmasbi, R. (2011) A Generalized Lindley Distribution. Sankhya B, 73, 331-359. https://doi.org/10.1007/s13571-011-0025-9</mixed-citation></ref><ref id="scirp.111569-ref11"><label>11</label><mixed-citation publication-type="other" xlink:type="simple">Okasha, H. and Mustafa, A. (2020) E-Bayesian Estimation for the Weibull Distribution under Adaptive Type-I Progressive Hybrid Censored Competing Risks Data. Entropy, 22, 9-30. https://doi.org/10.3390/e22080903</mixed-citation></ref><ref id="scirp.111569-ref12"><label>12</label><mixed-citation publication-type="journal" xlink:type="simple"><name name-style="western"><surname>Shanker</surname><given-names> R. </given-names></name>,<etal>et al</etal>. (<year>2015</year>)<article-title>Akash Distribution and Its Applications</article-title><source> International Journal of Probability and Statistics</source><volume> 4</volume>,<fpage> 65</fpage>-<lpage>75</lpage>.<pub-id pub-id-type="doi"></pub-id></mixed-citation></ref><ref id="scirp.111569-ref13"><label>13</label><mixed-citation publication-type="journal" xlink:type="simple"><name name-style="western"><surname>Shanker</surname><given-names> R. </given-names></name>,<etal>et al</etal>. (<year>2017</year>)<article-title>Akshaya Distribution and Its Application</article-title><source> American Journal of Mathematics and Statistics</source><volume> 7</volume>,<fpage> 51</fpage>-<lpage>59</lpage>.<pub-id pub-id-type="doi"></pub-id></mixed-citation></ref><ref id="scirp.111569-ref14"><label>14</label><mixed-citation publication-type="other" xlink:type="simple">Shanker, R., Hagos, F. and Sujatha, S. (2015) On Modeling of Lifetimes Data Using Exponential and Lindley Distributions. Biometrics &amp; Biostatistics International Journal, 2, 1-9. https://doi.org/10.15406/bbij.2015.02.00042</mixed-citation></ref><ref id="scirp.111569-ref15"><label>15</label><mixed-citation publication-type="other" xlink:type="simple">Smith, R.L. and Naylor, J.C. (1987) A Comparison of Maximum Likelihood and Bayesian Estimators for the Three-Parameter Weibull Distribution. Journal of the Royal Statistical Society: Series C (Applied Statistics), 36, 358-369.</mixed-citation></ref></ref-list></back></article>