1) Due to contamination over the eyes, mouth and nasal mucosa [11] [12], local acupuncture points related to these structures, around the nose, Bitong, LI 20 and Yintang, around the mouth, ST 4, DU 26 and around the eye, ST 1, UB 2 useable [6]. Using these points, by pricking the needle, in these contamination areas, creating microinflammation, cytokines such as TGF-α, TGF-β released from platelets in these regions, attract neutrophils to the region. During this period, we see that tissue macrophages are also active. After a while, it activates in other immune cells throughout the body. So when there is a viral infection in these areas, immune cells are ready to respond [13].

2) Respiratory transmission and initial exposure tonsilla, pharynx, trachea and owing to then it is in the lungs, we use the Yuan (Source) point LU 9 and Luo-connecting point LU 7 of the lung meridian.

3) Immunomodulatory points, LI4, ST36, SP6, REN 12, REN 6 points are used [13].

Purpose of acupuncture application in the medical observation stage; Motivating the antipathogenic qi of the human body, the functions of the lung and spleen and to distribute epidemic pathogens to strengthen the defense capacity of internal organs [14]. It has been reported in recent studies that the application to ST 36 acupuncture point with anti-inflammatory and anti-allergic properties is the most commonly used acupuncture point for immunomodulation [15]. Many studies provide evidence suggesting that acupuncture application to LI 4, SP 6 and REN 6 points, especially ST 36, causes a significant increase in natural killer (NK) cell activity [16]. In a controlled laboratory experiment, Hubei Chinese Medicine University researchers discovered that acupuncture point ST 36 (Zusanli) electroacupuncture stimulation “increases the level of immune cytokines and spleen CD4 + T cells through TRPV channels”. Findings are important because CD4 + T cells are very important in human immune systems. These cells are called helper T cells and are active in the immune system’s defense against microorganisms, including viruses. CD4 + T cells are capable of differentiating into many different cell subsets in activating the body’s immune system cells, immunoregulation and cytotoxic defense mechanisms. Application to ST 36 acupuncture point is effective in activating the immune system [17].

A large amount of porphyrin is needed for the virus to survive. New coronavirus attacks hemoglobin in erythrocytes and exposes porphyrin. Based on low levels of heme in coronavirus patients; It is considered that the virus binds directly with human hemoglobin. Porphyrin is an important material for heme synthesis. It is thought that the virus may be competing with iron for porphyrin as the cause of iron increase in the body [18]. Considering this physiopathology, we can add the Sp 10 (Sea of Blood) point used in Heat in the Blood syndrome to prophylaxis in blood related problems [19].

1) Wind-Cold Sendrome [8]

Clinical Findings: Heat (mostly low-grade fever), feeling uncomfortable with cold, chills, headache, discomfort from the throat, pain in the muscles.

Tongue Findings: Pale, coating is white and thin.

Pulse Findings: Weak and floating pulse.

Treatment Strategy: Wind and cold elimination.

Treatment: LU 9, LU 7, UB 12, UB 13, GB 20.

Note: Radiological findings of this period in current medicine, there is no finding in tomography.

2) Damp-Cold Sendrome [9]

Clinical Findings: Cough, tension in the chest, moderate difficulty breathing, weakness, decreased appetite, nausea, vomiting, swelling in the abdomen, diarrhea or constipation.

Tongue Findings: Pale tongue, adhesion and partially white coating on the tongue.

Pulse Findings: Weak and slippery pulse.

Treatment Strategy: Deactivation of humidity and cold.

Treatment: LU 9, LU 7, UB 12, UB 13, GB 20, ST 36, ST 40, SP 9.

For Lung Strengthening (Tonification); LU 9, LU 7, UB 13.

To Inactivate Damp; ST 36, ST 40, SP 9.

3) Heat Attacking the Lung [8]

Clinical Findings: Heat, discomfort from the cold, dry cough, insufficient phlegm, pain and painful muscles in the limbs, weakness, headache.

Tongue Findings: Trunk and tip are red, yellow coating on it.

Pulse Findings: Rapid pulse.

Treatment Strategy: Deactivating heat from the lung.

Treatment: LU 9, LU 7, UB 13, UB 14, UB 15, LI 4, LI 11, DU 14.

For Lung Strengthening (Tonification); LU 9, LU 7, UB 13, UB 14, UB 15.

To Disable Heat: LI 4, LI 11, DU 14.

Note: Radiological findings of this period in current medicine, tomography shows scattered ground glass opacity in both lungs.

4) Damp-Heat Attacking the Lung [8]

Clinical Findings: Heat, advanced shortness of breath, dry cough, having sputum but having difficulty removing sputum, general pains in the body, headache, weakness, fatigue, recumbency want, nausea and vomiting, diarrhea.

Tongue Findings: Trunk and tip red, sticky and yellow coating on the tongue, tooth marks on the edge of the tongue.

Pulse Findings: Rapid and slippery pulse.

Treatment Strategy: Inactivation of damp and heat from the lung.

Treatment: LU 9, LU 7, LU 10, LI 4, LI 11, DU 14, ST 36, ST 40, SP 9.

For Lung Strengthening (Tonification); LU 9, LU 10, LU 7.

To Disable Heat; LI 4, LI 11, DU 14.

To Inactivate Damp; ST 36, ST 40, SP 9.

Note: Radiological findings of this period in current medicine, tomography shows that both lungs have a glass opacity in more than one scattered or large area.

5) Blockage-Collapse in the Lungs and Visceral Organs [8] [Patient Group to be treated in intensive care]*

Clinical Findings: Very severe breathlessness and as a result a feeling of suffocation, wheezing, increased breathing frequency (These patients can only maintain their breathing with a respiratory support device).

Tongue Findings; Dark purplish tongue, yellow dry tongue coating or thick and oily yellow coating.

Pulse Findings; Rapid and slippery pulse.

Urine: Red colored urine (erythrocytes in the urine).

*Treatment Strategy: In this period, we do not think that acupuncture will be effective because the patients are connected to the respiratory device and the lungs are under the control of the device.

Note: Radiological findings of this period in current medicine, tomography shows glass opacity in more than one large area in both lungs.

6) Lung and Spleen Qi Deficiency [9] [20] [Recovery Period]

Clinical Findings: Fatigue, anorexia, nausea, abdominal distention and fullness, constipation or loose sticky stool.

Tongue Findings: A swollen tongue, white and sticky coating on it.

Pulse Findings: Deep and slow pulse.

Treatment Strategy: Strengthening the Qi, lung and spleen [6].

Treatment: LU 9, LU 7, UB 12, UB 13, ST 36, ST 40, SP 9.

For Lung Strengthening (Tonification); LU 9, LU 7, UB 13.

Strengthening the Spleen; ST 36, ST 40, SP 9.