Actually, we got 209 doctors in the study. There were 37 student doctors in their final school year in medicine and 172 general practitioners. Most of the doctors were from Benin medical faculty (98.1%) and mainly from the Faculty of Health Sciences (FSS) in Cotonou (80.9%). The average age was 27.5 years with a minimum of 22 and a maximum of 34.

Our study population was general practitioners and final school year students. Their age on average was 27.5 years and their average seniority period was 2.9 years. This population is quite young compared to the one in the studies of Rat et al. concerning the management of rheumatoid arthritis in general practice where the average age was 49 years [7] or the work of Badoum et al. on the knowledge, attitudes and practices of general practitioners on asthma in Ouagadougou, where the average age was 34 years [8]. Most of the doctors were graduated from the faculties of Benin. Our study was indeed led in Cotonou where the largest and oldest medical faculty in the country is located. Thus, doctors who recently got graduated or are waiting to defend, work in that city of their training faculty or in neighboring localities while waiting for more stable professional projects. This situation also explains the relatively low average age and seniority length.

Most of the doctors worked in polyclinics or local hospitals. Actually, these centers rarely offer permanent contracts. Indeed, these health facilities tend to employ a greater number of general practitioners and students to ensure continuity and on-call duty to manage the flow of patients.

Clinics and medical offices generally employ a single doctor who is in charge of ensuring continuity and not on-call.

Teaching hospitals most often offer stable jobs. However, these are the reference teaching hospitals where most of the practicing doctors are specialists or are in the process of being specialists.

The current results of the study revealed a low level of knowledge of general practitioners about SLE. Actually, 17 doctors (8.1%) stated not to have heard about this disease. Among the 192 physicians remaining, 191 had a limited knowledge of SLE. Blaauw et al. in 1995 demonstrated that it was one of the most difficult diagnoses for general practitioners [9]. This finding in our work has also been noticed in the case of several other diseases in different other studies. Thus, Rat et al. in their studies related to general practitioners in the management of rheumatoid arthritis confirmed that there are important gaps in the knowledge of general practitioners on this disease [7] [8]. The analyses of these studies allow us to identify the lack in the care of patients, due to a lack of theoretical knowledge of general practitioners, in fact in numerous majors of medicine. Bloy [10] also noted a notion of uncertainty that is attached to the condition of general practitioners. According to her, this uncertainty is due to the relationship of the general practitioner to medical knowledge and social relations that are required by his position. In the first case, the uncertainty is deployed on three different levels: a level 1 that “results from an incomplete or imperfect mastery of the available knowledge”, a level 2 that “depends on the limits related to medical knowledge” these days, and a level 3 that is due to the issue for a given practitioner to balance for the first and second levels. She even wrote that among all the doctors, the general practitioner is the one who deals with the most extensive field of knowledge, even infinitely, his “specialty” is not well limited a priori. “Incomplete or imperfect mastery of available knowledge” is therefore its concern, and even more.

Whatever personal efforts he makes or the quality of his initial training, the general practitioner has become, and will remain, the one who knows a little of everything.

In our study, we find that the primary source of information for surveyed doctors about SLE was their initial medical education. Internal medicine was the main teaching discipline which was followed by the dermatology. In the content of the doctors training at the Cotonou FSS, lupus has been taught in the dermatology program for several decades and in internal medicine for a year. This shows the need to strengthen the knowledge of general practitioners through postgraduate teaching. The level of knowledge, and therefore the level of uncertainty, changes with the addressed points in the different majors of medical knowledge. Thus, the factor contributing the most and cited by doctors was pregnancy (69.3% or 133), and it is followed by exposure to the sun and some drugs. This is because they are the most frequently found factors [11].

The best known manifestations are general, mucosal skin, and rheumatic. They are also the most frequent and common manifestations of systemic lupus [12] [13].

Among the general manifestations, fever was the most cited; it is also the most common general sign; however it is not always related to SLE itself but rather to infectious complications of the treatment [14].

The most well-known mucosal skin manifestation by physicians was erythema malaria vespertilio. It is one of the specific lesions of SLE and it gives the disease its etymological origin [14].

Only 44.8% of physicians who reported the existence of mucosal skin manifestations in SLE mentioned discoid lesions, among them, 27.6% cited skin necrosis, and a quarter of them chose oral erosions. Urticarial lesions, alopecia, livedo, and vasculitis lesions are the least mucosal skin manifestations that were revealed. This is somehow an evidence of the fact that despite the great specificity of these different lesions [14], they are still not well understood by general practitioners. Among the rheumatic manifestations, the most cited by doctors were arthritis and arthralgia (62.0%) and myalgia (49.0%). These manifestations are indeed among the most frequent of the group of rheumatologic manifestations [14]. Jaccoud’s deformation was the least mentioned despite its great specificity [14].

Among physicians, 82.8% are aware of the existence of renal manifestations of SLE, but only 21.5% know about the prognostic importance of these attacks. The determining nature of these manifestations in the prognosis [12] explains their systematic research by specialist practitioners and it could explain the fact that general practitioners know their existence but not their characteristics, including prognostic importance. Thus, the almost constant glomerular character of renal involvement, for example [14], was not known to a third of the doctors.

The cardiovascular manifestations of SLE have been enumerated [14], among the most serious by physicians. However, they are not well known to doctors since the most frequently mentioned endocarditis has only been mentioned twice in five.

The neuropsychiatric manifestations of SLE have also been correctly cited among the most serious. They are also poorly understood since hallucinations, delusions, psychosis, and confusional states, although not frequent and not very specific [14], were the most cited. However, strokes and seizures, found frequently in patients, were mentioned by less than a third of physicians.

The best-known breathing manifestation of SLE by physicians was pleurisy. It was cited by 41.1% of them. It is also one of the most common breathing manifestations [14]. The most mentioned hematologic manifestation by physicians was the acceleration of SV. Hemolytic anemia was only cited by 28.1% of physicians despite its high frequency [14].

Only 12.9% of physicians cited native anti-DNA antibodies among the antibodies to be assayed in SLE. However, these are the most specific antibodies to the disease [12] [14]. Regarding the classification criteria, those of the American College of Rheumatology (ACR) were chosen by 17.2% of physicians, those of the SLICC by only 1.6%. Trépos et al., in their study of general practitioners and medical recommendations have shown that while they approve of the growing role of recommendations in medical practice and strive to take it into account, general practitioners rely primarily on their experience of practitioners to sort through the mass of recommendations they received. The knowledge of general practitioners on the diagnosis of lupus is thus limited.