<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article  PUBLIC "-//NLM//DTD Journal Publishing DTD v3.0 20080202//EN" "http://dtd.nlm.nih.gov/publishing/3.0/journalpublishing3.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="3.0" xml:lang="en" article-type="research article"><front><journal-meta><journal-id journal-id-type="publisher-id">OJTR</journal-id><journal-title-group><journal-title>Open Journal of Therapy and Rehabilitation</journal-title></journal-title-group><issn pub-type="epub">2332-1822</issn><publisher><publisher-name>Scientific Research Publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.4236/ojtr.2020.84013</article-id><article-id pub-id-type="publisher-id">OJTR-103403</article-id><article-categories><subj-group subj-group-type="heading"><subject>Articles</subject></subj-group><subj-group subj-group-type="Discipline-v2"><subject>Medicine&amp;Healthcare</subject></subj-group></article-categories><title-group><article-title>
 
 
  The Question of Short Lower Limb and Long Lower in Manual Therapy: An Overview
 
</article-title></title-group><contrib-group><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Luca</surname><given-names>Collebrusco</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Giovanna</surname><given-names>Censi</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Paola</surname><given-names>Casoli</given-names></name><xref ref-type="aff" rid="aff3"><sup>3</sup></xref></contrib></contrib-group><aff id="aff1"><addr-line>Rehabilitation Unit, National Health Service of Umbria, Perugia, Italy</addr-line></aff><aff id="aff2"><addr-line>INRCA, University Polytechnic of Marche, Ancona, Italy</addr-line></aff><aff id="aff3"><addr-line>Neurorehabilitation Clinic, University Polytechnic of Marche, Ancona, Italy</addr-line></aff><pub-date pub-type="epub"><day>27</day><month>08</month><year>2020</year></pub-date><volume>08</volume><issue>04</issue><fpage>143</fpage><lpage>152</lpage><history><date date-type="received"><day>6,</day>	<month>September</month>	<year>2020</year></date><date date-type="rev-recd"><day>11,</day>	<month>October</month>	<year>2020</year>	</date><date date-type="accepted"><day>14,</day>	<month>October</month>	<year>2020</year></date></history><permissions><copyright-statement>&#169; Copyright  2014 by authors and Scientific Research Publishing Inc. </copyright-statement><copyright-year>2014</copyright-year><license><license-p>This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/</license-p></license></permissions><abstract><p>
 
 
  The purpose of this paper is to review relevant literature concerning limb length inequalities in adults and to make recommendations for assessment and intervention based on the literature and our own clinical experience. The research was carr
  ied
   out on PUB MED, Non-English articles and duplicates in the databases were not included. Limb length inequality and common classification criteria are defined and etiological factors are present. Common methods of detecting limb length inequality include model manual technics. This work has the purpose of describing a well standardized therapeutic in the form of practical guidance. The approach we describe provides standardized model evaluation for leg lower limb in order to be used in rehabilitation clinic.
 
</p></abstract><kwd-group><kwd>Leg Length Discrepancy</kwd><kwd> Leg Length Inequality</kwd><kwd> Diagnostic Techniques and Procedures</kwd></kwd-group></article-meta></front><body><sec id="s1"><title>1. Introduction</title><p>Leg length discrepancy (LLD) has been found to be a significant factor influencing several pathological and physiological conditions, which affect function and quality of life [<xref ref-type="bibr" rid="scirp.103403-ref1">1</xref>] [<xref ref-type="bibr" rid="scirp.103403-ref2">2</xref>]. LLD occurs in about 40% - 70% of the population. Most have a leg length difference smaller than 20 mm. The past several decades, limb length inequality has been the topic of a great deal of disagreement among clinical investigators and researchers. The existence of limb length inequality is not in doubt. Little agreement exists, however, regarding the degree of limb length inequality that is considered clinically significant [<xref ref-type="bibr" rid="scirp.103403-ref3">3</xref>]. Several classification systems or categories of limb length inequality have been propos. The most common classification scheme for limb length inequality identifies two types: anatomical and functional [<xref ref-type="bibr" rid="scirp.103403-ref4">4</xref>]. The therapist effects specific manual sequences for differential limb length discrepancy. The LLD not only restrict bony mobility, but also compress neurovascular and fascial structures and disturb their functions. The assessment LLD can be defined as an evaluative model for the management of patients with musculoskeletal disorders according to International Classification of Disease (ICD), ICD-10-CM, M 99.09 in somatic dysfunction (SD), which implies that a dysfunctional and segmental event of a part of the body can give a remote repercussion in another regional complex [<xref ref-type="bibr" rid="scirp.103403-ref5">5</xref>]. It is not easy to establish in clinical practice if a LLD is structural (SLLD) or functional (FLLD), despite the theoretical distinction. A SLLD is considered an actual shortening of the skeletal system between the hip of and ankle joint, the anatomical difference between the lengths of the two limbs between the proximal edge of the femoral head to the distal edge of the tibia, which can be congenital or acquired [<xref ref-type="bibr" rid="scirp.103403-ref6">6</xref>]. A FLLD can occur as result of joints misalignment of lower limbs and rotated pelvis [<xref ref-type="bibr" rid="scirp.103403-ref5">5</xref>] [<xref ref-type="bibr" rid="scirp.103403-ref7">7</xref>] [<xref ref-type="bibr" rid="scirp.103403-ref8">8</xref>] can cause alteration of lower limb mechanics, such as joint contracture, static or dynamic mechanical axis misalignment, muscle weakness or shortening. The therapist selects sequence a group manual tests for classification lower limbs discrepancy. The techniques will also be classified according to the type of manoeuvres described in the literature and will be explained in detail [<xref ref-type="bibr" rid="scirp.103403-ref9">9</xref>]. The present paper defines a simple assessment plan for therapists, which is design for LLD in the context of SD assessment. We provide an overview of its management according to the current evidence-based literature. A number of different assessment tools and methods are proposed.</p></sec><sec id="s2"><title>2. Criteria and Strategies Research Assessment LLD</title><p>The assessment of the limbs must include inspection of the patient, gait analysis, and palpation and movement of both limbs [<xref ref-type="bibr" rid="scirp.103403-ref10">10</xref>] [<xref ref-type="bibr" rid="scirp.103403-ref11">11</xref>] [<xref ref-type="bibr" rid="scirp.103403-ref12">12</xref>] [<xref ref-type="bibr" rid="scirp.103403-ref13">13</xref>]. Early recognition of leg length discrepancy is essential for correct homeostasis and quality of life the patient [<xref ref-type="bibr" rid="scirp.103403-ref14">14</xref>] [<xref ref-type="bibr" rid="scirp.103403-ref15">15</xref>] [<xref ref-type="bibr" rid="scirp.103403-ref16">16</xref>]. A brief description of each available method used to determine LLD, will be illustrated below (<xref ref-type="fig" rid="fig1">Figure 1</xref>).</p></sec><sec id="s3"><title>3. Methods used for Assessing LLD in the Practical</title><p>Direct assessment of apparent LLD during physical examination is performed with the patient supine and involves measuring from the anterior superior iliac spines (ASIS) to the medial malleolus (<xref ref-type="fig" rid="fig2">Figure 2</xref>(A)) [<xref ref-type="bibr" rid="scirp.103403-ref17">17</xref>], (true leg length discrepancy with oblique pelvis). Always with the patient supine, the examiner uses a tape measure to assess the distance between the umbilicus and the medial malleolus (<xref ref-type="fig" rid="fig2">Figure 2</xref>(B)). Leg length assessments or the prone check (<xref ref-type="fig" rid="fig3">Figure 3</xref>), the participants approached the foot of the table and knelt on the foot of the table. The participants then lay prone, using their arms to pull the body cephalad until the ankles were at the foot of the table, attempting to remove any table positioning artefacts. For the supine check (<xref ref-type="fig" rid="fig4">Figure 4</xref>), the participants approached the foot</p><p>of the table and sat down at the foot of the table. They then used their arms to pull their seated bodies toward the head of the table until their ankles cleared the foot of the table, attempting to remove any table positioning artefacts. The examiners were required to judge either the left or the right leg short [<xref ref-type="bibr" rid="scirp.103403-ref18">18</xref>]. Assessment for leg length inequality in the prone position may detect consequences of pelvic torsion, whereas supine assessment may detect consequences of upper</p><p>cervical segmental misalignment [<xref ref-type="bibr" rid="scirp.103403-ref18">18</xref>]. Abnormal pronation patterns we quantified using the Foot Posture Index (FPI) in a modified stance position: arms extended, forward lean against the wall, knees sufficiently bent to load the forefoot, score FPI &lt; 2 from abnormal pronation for misalignment leg length (<xref ref-type="fig" rid="fig5">Figure 5</xref>).</p><p>The relative position of the posterior superior iliac spines. With the subject standing relaxed, unshod, and with vision directed forward, the posterior superior iliac spines (PSIS) were located by palpation (<xref ref-type="fig" rid="fig6">Figure 6</xref>).</p><p>The dysfunction pelvic model is delineated as follows: Abnormal pronation pulls the innominate bones anteriorly; anterior rotation of the innominate bones pulls the acetabula, and the femoral heads, cephalad (upward) and posteriorly; and this, in turn, hyperextends the knees and functionally shortens the legs, with the shortest leg associated with the more pronated foot. The supine prone and standing positions may have different impacts on functional leg length inequality.</p><p>We can have two answers to the evaluation:</p><p>- FLLD: leg length &lt; 3 - 9 mm, and pronated feet in a modified stance position FPI score &lt; 2 [<xref ref-type="bibr" rid="scirp.103403-ref19">19</xref>].</p><p>- SLLD: leg length &gt; 9 mm, and pronated feet in a modified stance position FPI score &gt; 2, (PFI) [<xref ref-type="bibr" rid="scirp.103403-ref19">19</xref>].</p><p>In SLLD assessment associated may occur visual impairments, inner ear or balance problems, history of trauma to the hip or lower limb, history of surgery of the lower limb, and history of neurologic deficits that affect foot or hip posture. Imaging methods are included in the evaluation of the SLLD, there is general agreement that radiographs are more accurate and reliable than clinical methods for assessing LLD [<xref ref-type="bibr" rid="scirp.103403-ref20">20</xref>]. Although various imaging techniques have been used to evaluate leg-length inequality, plain Radiography remains the gold standard [<xref ref-type="bibr" rid="scirp.103403-ref21">21</xref>], standing anterior-posterior radiograph of the lower extremity (modified teleoroentgenogram).</p></sec><sec id="s4"><title>4. Discussion</title><p>Leg length discrepancy can be structural or functional; both can cause postural compensations that contribute to pain and/or functional compromise. However, there are potential sources of error with tape measurements related to differences in leg circumference, angular deformities, and difficulty in accurately palpating bony prominences as well as joint contractures [<xref ref-type="bibr" rid="scirp.103403-ref22">22</xref>]. Positive correlation exists between the most pronated foot and the shortest leg [<xref ref-type="bibr" rid="scirp.103403-ref22">22</xref>] [<xref ref-type="bibr" rid="scirp.103403-ref23">23</xref>] [<xref ref-type="bibr" rid="scirp.103403-ref24">24</xref>]. LLD may result in degenerative changes of the lumbar spine, altered gait mechanics, and low back pain [<xref ref-type="bibr" rid="scirp.103403-ref25">25</xref>]. Some studies suggest that LLD is associated with low back pain [<xref ref-type="bibr" rid="scirp.103403-ref26">26</xref>]. LLD causes pelvic obliquity in the frontal plane [<xref ref-type="bibr" rid="scirp.103403-ref27">27</xref>]. The length discrepancy of lower limbs leads to posture deformation, gait asymmetry, low back pain, discopathy as well as gonarthrosis, coxarthrosis and hip flexion contracture on the side of the longer extremity or ankle joint contracture in the equine position on the side of the shorter extremity, with lumbar convexity towards the short lower limb [<xref ref-type="bibr" rid="scirp.103403-ref27">27</xref>]. The discrepancies of 5 to 25 mm are not necessarily a functional detriment to marathon runners, and no consistent benefits could be attributed to the use of a lift [<xref ref-type="bibr" rid="scirp.103403-ref28">28</xref>].</p><p>Analysis of the data, using 10 mm as the threshold of difference, reveals high levels correlation and no significant difference between measurements obtained from standing and supine radiographs. A weak correlation and statistical difference existed between each set of radiographic measurements and physical examination measurements [<xref ref-type="bibr" rid="scirp.103403-ref29">29</xref>]. A radiographic investigation for leg length inequality should be considerd as the cause of low back pain, an x-ray of the standing posture of the entire pelvis and lumbar spine are essential to assess existing pelvic tilt and scoliosis [<xref ref-type="bibr" rid="scirp.103403-ref30">30</xref>]. There are large differences between prone and radiographic measurements in some cases indicating that caution should be exercised when using the prone-only method to estimate leg length discrepancy [<xref ref-type="bibr" rid="scirp.103403-ref31">31</xref>]. There is an association between mild leg length inequality and LBP [<xref ref-type="bibr" rid="scirp.103403-ref32">32</xref>]. Asymmetry, including compensatory scoliosis with leg length difference, there was no difference in predisposition in trunk flexion fatigue [<xref ref-type="bibr" rid="scirp.103403-ref33">33</xref>]. Precise determination of LLD is an important problem. The assessment LLD is associated with numerous postural alignment challenges presented in algorithm. The work is the result of the literature review includes both review articles and clinical trial articles grouped in <xref ref-type="table" rid="table1">Table 1</xref> who based on sample size, average age of patients and population.</p><p>To provide an evidence-based instrument to aid the clinician in a practical approach to evaluation and treatment in manual therapy, previous clinical methods have limited reliability and depending on them for determining the need for intervention, might be misleading. There are still differences of opinions as to the role LLD plays in musculoskeletal disorders. Some investigators accept as</p><table-wrap id="table1" ><label><xref ref-type="table" rid="table1">Table 1</xref></label><caption><title> Studies using reliable means of determining magnitude of anatomic leg-length inequality</title></caption><table><tbody><thead><tr><th align="center" valign="middle" >STUDY</th><th align="center" valign="middle" >SAMPLE SIZE</th><th align="center" valign="middle" >MIDDLE AGE</th><th align="center" valign="middle" >POPOLATION</th></tr></thead><tr><td align="center" valign="middle" >Gross R. et al. 1983</td><td align="center" valign="middle" >35</td><td align="center" valign="middle" >35</td><td align="center" valign="middle" >MARATHON RUNNERS</td></tr><tr><td align="center" valign="middle" >Venn E.K.et al. 1983</td><td align="center" valign="middle" >60</td><td align="center" valign="middle" ></td><td align="center" valign="middle" >RANDOMLY CHOSEN PATIENTS</td></tr><tr><td align="center" valign="middle" >Cleveland R.H. et al. 1998</td><td align="center" valign="middle" >10 6 men - 4 women</td><td align="center" valign="middle" >41</td><td align="center" valign="middle" >LOW BACK PAIN PATIENTS</td></tr><tr><td align="center" valign="middle" >Hoikka V. et al. 1989</td><td align="center" valign="middle" >100 53 men - 47 women</td><td align="center" valign="middle" >40</td><td align="center" valign="middle" >CHRONIC LOW BACK PAIN</td></tr><tr><td align="center" valign="middle" >BEATTLE P. et al. 1990</td><td align="center" valign="middle" >19 9 men - 10 women</td><td align="center" valign="middle" >30</td><td align="center" valign="middle" >CLINICAL SUBJECTS</td></tr><tr><td align="center" valign="middle" >SOUKKA A. et al. 1991</td><td align="center" valign="middle" >247</td><td align="center" valign="middle" >44</td><td align="center" valign="middle" >LOW BAKC PAIN</td></tr><tr><td align="center" valign="middle" >RHODES D.W. et al. 1995</td><td align="center" valign="middle" >50</td><td align="center" valign="middle" ></td><td align="center" valign="middle" >LOW BACK PAIN</td></tr><tr><td align="center" valign="middle" >MINCER et al. 1997</td><td align="center" valign="middle" >54 10 men - 44 women</td><td align="center" valign="middle" ></td><td align="center" valign="middle" >VOLUNTEERS</td></tr><tr><td align="center" valign="middle" >HAVRAN M. et al. 1998</td><td align="center" valign="middle" >1 men</td><td align="center" valign="middle" >84</td><td align="center" valign="middle" >CHRONIC LOW BACK PAIN</td></tr><tr><td align="center" valign="middle" >HYMAN A. et al. 2006</td><td align="center" valign="middle" >8 men</td><td align="center" valign="middle" ></td><td align="center" valign="middle" >LLD and SUBMALLEOLAR DEFORMITY</td></tr><tr><td align="center" valign="middle" >BRIAN A. et al. 2006</td><td align="center" valign="middle" >100</td><td align="center" valign="middle" >48</td><td align="center" valign="middle" >LLD and SCOLIOSIS and LOW BACK PAIN</td></tr><tr><td align="center" valign="middle" >RANNISTO S. et al. 2015</td><td align="center" valign="middle" >114 88 men - 26 women</td><td align="center" valign="middle" ></td><td align="center" valign="middle" >LLD and LOW BACK PAIN</td></tr><tr><td align="center" valign="middle" >JAN W. et al. 2010</td><td align="center" valign="middle" >369 160 men - 209 women</td><td align="center" valign="middle" >10</td><td align="center" valign="middle" >LLD and PELVIC OBLIQUITY and SCOLIOSIS</td></tr></tbody></table></table-wrap><p>much as 20 - 30 mm, while others define a significant discrepancy of 3 - 5 mm [<xref ref-type="bibr" rid="scirp.103403-ref6">6</xref>] [<xref ref-type="bibr" rid="scirp.103403-ref26">26</xref>] [<xref ref-type="bibr" rid="scirp.103403-ref34">34</xref>]. We believe that physiotherapist should not depend solely on tape measure measurements for clinical decisions. The assessment LLD can aid in recognizing the contribution of segmental alignment and joint movement on effective leg length and accordingly, decide if there is a need for intervention manual therapy [<xref ref-type="bibr" rid="scirp.103403-ref34">34</xref>].</p></sec><sec id="s5"><title>5. Conclusions</title><p>To promote a patient centred approach, providers should consider evaluating for LLD in somatic dysfunction. A benefit of the screening examination is that the patient is examined in standing, sitting, supine, and prone. This permits assessment in both weight bearing and non-weight-bearing positions.</p><p>Each component of the lower extremity is systematically examined to determine possible contributing factors to limb length inequality [<xref ref-type="bibr" rid="scirp.103403-ref35">35</xref>]. The question of whether to treat individuals with LLD should be taken on a case-to-case basis. The Knowledge for assessment FLLS and SLLD may assist clinicians in understanding tissue stress patterns that are associated with skeletal misalignments. This knowledge is essential in making decisions regarding activity modification, manual therapy and postural therapy. The detection of LLD should base on the integration of the static and dynamic assessment, dynamic leg length during the gait cycle, imaging if available. The combination of these assessments can provide a more precise measurement for evaluation LLD. By adding the FLLD and SLLD concept in manual therapy, it would make the clinical faster and more standardized.</p></sec><sec id="s6"><title>Conflicts of Interest</title><p>The authors declare no conflicts of interest regarding the publication of this paper.</p></sec><sec id="s7"><title>Cite this paper</title><p>Collebrusco, L., Censi, G. and Casoli, P. 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