<?xml version="1.0" encoding="UTF-8"?><!DOCTYPE article  PUBLIC "-//NLM//DTD Journal Publishing DTD v3.0 20080202//EN" "http://dtd.nlm.nih.gov/publishing/3.0/journalpublishing3.dtd"><article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" dtd-version="3.0" xml:lang="en" article-type="research article"><front><journal-meta><journal-id journal-id-type="publisher-id">WJCD</journal-id><journal-title-group><journal-title>World Journal of Cardiovascular Diseases</journal-title></journal-title-group><issn pub-type="epub">2164-5329</issn><publisher><publisher-name>Scientific Research Publishing</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.4236/wjcd.2020.107042</article-id><article-id pub-id-type="publisher-id">WJCD-101474</article-id><article-categories><subj-group subj-group-type="heading"><subject>Articles</subject></subj-group><subj-group subj-group-type="Discipline-v2"><subject>Medicine&amp;Healthcare</subject></subj-group></article-categories><title-group><article-title>
 
 
  Right Atrium Myxoma in an 11-Year-Old Girl in Guinea
 
</article-title></title-group><contrib-group><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Barry</surname><given-names>Ibrahima Sory</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Balde</surname><given-names>El Hadj Yaya</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Camara</surname><given-names>Abdoulaye</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref><xref ref-type="corresp" rid="cor1"><sup>*</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Koivogui</surname><given-names>Kokoulo</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Samoura</surname><given-names>Aly</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Koivogui</surname><given-names>Diarra</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Soumaoro</surname><given-names>Morlaye</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Toure</surname><given-names>Demba</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Camara</surname><given-names>Aboubacar</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Bah</surname><given-names>Mamadou Bassirou</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Sylla</surname><given-names>Fatou</given-names></name><xref ref-type="aff" rid="aff2"><sup>2</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Beavogui</surname><given-names>Mariame</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Balde</surname><given-names>Mamadou Dadhi</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Conde</surname><given-names>Mamady</given-names></name><xref ref-type="aff" rid="aff1"><sup>1</sup></xref></contrib></contrib-group><aff id="aff2"><addr-line>Pneumology department of the Ignace Deen National Hospital CHU, Conakry, Republic of Guinea</addr-line></aff><aff id="aff1"><addr-line>Department of Cardiology at Ignace Deen National Hospital CHU, Conakry, Republic of Guinea</addr-line></aff><pub-date pub-type="epub"><day>13</day><month>07</month><year>2020</year></pub-date><volume>10</volume><issue>07</issue><fpage>432</fpage><lpage>436</lpage><history><date date-type="received"><day>26,</day>	<month>February</month>	<year>2020</year></date><date date-type="rev-recd"><day>11,</day>	<month>July</month>	<year>2020</year>	</date><date date-type="accepted"><day>14,</day>	<month>July</month>	<year>2020</year></date></history><permissions><copyright-statement>&#169; Copyright  2014 by authors and Scientific Research Publishing Inc. </copyright-statement><copyright-year>2014</copyright-year><license><license-p>This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/</license-p></license></permissions><abstract><p>
 
 
  The objective of this study was to describe the myxoma of the right atrium occurring in an 11-year-old girl. It was an 11
  -
  year
  -
  old girl weighing 22 kg, admitted for exertional dyspnea, dry cough, palpitations, hepatitis, abdominal bloating, fever evolving for more than 9 months without a history of known cardiovascular disease; referral from a pulmonology department for cardiomegaly and right pleurisy.
   
  At cardiac auscultation, the rhythm was irregular
  ly
   fast at 130 beats without added noise with a blood pressure of 110/65
   
  mmhg. In the lungs, there was silence and a decrease in vocal vibrations at the right base, SaO<sub>2</sub> at 70%. Elsewhere a thoracic collateral venous circulation was visible. Electrocardiogram recorded rapid atrial fibrillation at 134 cycles. The cardiac ultrasound concluded that there was a mobile mass in the right atrium prolapsing in the right ventricle measuring 25 mm &#215; 18.9 mm suggesting a myxoma. The myxoma of the right atrium is of a rare localization with a polymorphic clinical manifestation. It should be diagnosed as early as possible to avoid the occurrence of dreaded complications. Its management is surgical.
 
</p></abstract><kwd-group><kwd>Myxoma</kwd><kwd> Right Atrium</kwd><kwd> 11-Year-Old Girl</kwd><kwd> Guinea</kwd></kwd-group></article-meta></front><body><sec id="s1"><title>1. Introduction</title><p>About 80% of primary cardiac tumors are benign, more than half of which are myxomas [<xref ref-type="bibr" rid="scirp.101474-ref1">1</xref>]. The atrium myxoma is a rare benign tumor. Its location in the right atrium is unusual and is found in 15% to 20% of cases of cardiac myxoma [<xref ref-type="bibr" rid="scirp.101474-ref2">2</xref>]. This form can be complicated by pulmonary embolism and right heart failure and it is characterized by a clinical picture often misleading [<xref ref-type="bibr" rid="scirp.101474-ref3">3</xref>] [<xref ref-type="bibr" rid="scirp.101474-ref4">4</xref>] [<xref ref-type="bibr" rid="scirp.101474-ref5">5</xref>]. The objective of this study was to describe the myxoma of the right atrium occurring in an 11-year-old girl.</p></sec><sec id="s2"><title>2. Observation</title><p>It was an 11-year-old girl weighing 22 kg, admitted for exertional dyspnea, dry cough, palpitations, hepatitis, abdominal bloating, fever developing for more than 9 months. Without a history of known cardiovascular disease; referral from a pulmonology department for cardiomegaly and right pleurisy, at cardiac auscultation, the rhythm was irregular fast at 130 beats without added noise with a blood preasure at 110/65 mmhg. In the lungs, there was silence and a decrease in vocal vibrations at the right base, SaO<sub>2</sub> at 70%. Elsewhere a thoracic collateral venous circulation was visible. Electrocardiogram recorded rapid atrial fibrillation at 134 cycles. The cardiac ultrasound concluded that there was a mobile mass in the prolapsing right atrium in the right ventricle measuring 25 mm &#215; 18.9 mm suggesting a myxoma (<xref ref-type="fig" rid="fig1">Figure 1</xref>). The abdominal ultrasound showed an aspect in favor of the cardiac liver with a hepatic arrow at 13.5 cm and dilation of the inferior vena cava. The chest x-ray showed an overflow from the right lower arch, cardiomegaly with a cardiothoracic index of 0.57, and filling of the right diaphragmatic costo sac sac. Biology revealed anemia of 10 g/dl; a leukocytosis at 28 giga/l; a hyper lymphocytosis at 13.5 giga/l, the retroviral serology was negative. The rest of the exam was unremarkable.</p><p>At the end of the clinical and para-clinical examination, the diagnosis of myxoma of the right atrium was retained. The girl had benefited from treatment with anti aldosterone, a beta blocker and oxygen therapy. The excision of the myxoma was</p><p>not done for lack of technical platform for cardiac surgery. The evolution was marked by the patient’s death the day after her admission. The evolution was marked by the death of the patient.</p></sec><sec id="s3"><title>3. Discussion</title><p>We report the case of a right atrium myxoma in an 11-year-old girl in Guinea.</p><p>Myxoma can occur at any age, but more commonly between 30 and 60 years of age [<xref ref-type="bibr" rid="scirp.101474-ref6">6</xref>]. A predominance of women has been reported by most studies [<xref ref-type="bibr" rid="scirp.101474-ref6">6</xref>] [<xref ref-type="bibr" rid="scirp.101474-ref7">7</xref>]. Our subject was female and only 11 years old, unlike that reported by Noureddine Atmani in Rabat who was 60 years old and male. [<xref ref-type="bibr" rid="scirp.101474-ref8">8</xref>] Clinically, cardiac myxomas are generally revealed by one of the elements of the classic triad: general nonspecific signs, peripheral embolism or a valve obstruction or cardiac chambers [<xref ref-type="bibr" rid="scirp.101474-ref9">9</xref>]. This patient was admitted for dyspnea, hepatitis, abdominal bloating related to ascites and a fever. Right atrium myxomas frequently have a polymorphic and non-specific clinical picture [<xref ref-type="bibr" rid="scirp.101474-ref3">3</xref>] [<xref ref-type="bibr" rid="scirp.101474-ref10">10</xref>], which is often a source of diagnostic delay. In a study of symptomatic patients with atrial myxoma, the average time between onset of symptoms and diagnosis is 10.6 months. Thus approximately 15% of cardiac myxomas are discovered fortuitously [<xref ref-type="bibr" rid="scirp.101474-ref11">11</xref>]. The onset of symptoms and the diagnosis of myxoma were approximately 9 months. Trans thoracic ultrasound is the benchmark examination for diagnosis, it allows the diagnosis of the tumor and the study of different cardiac structures [<xref ref-type="bibr" rid="scirp.101474-ref3">3</xref>]. This is the case of our patient in whom Cardiac ultrasound concluded the presence of a mobile mass in the right atrium prolapsing in the right ventricle measuring 25 mm &#215; 18.9 mm evoking a myxoma (<xref ref-type="fig" rid="fig1">Figure 1</xref>). ETO is more sensitive for the detection of myxomas, especially when they are small. However, it can be dangerous, Cavero et al. [<xref ref-type="bibr" rid="scirp.101474-ref12">12</xref>] reported a case of sudden death from massive pulmonary embolism during TEE. The treatment of cardiac myxomas is surgical. The principles of this treatment have been listed by Jones [<xref ref-type="bibr" rid="scirp.101474-ref13">13</xref>]: minimal manipulation of the heart and tumor; adequate exposure allowing the entire tumor to be removed; inspection of the four heart chambers; the reduction of recurrences; be safe and effective. Our patient did not benefit from surgical excision of this tumor due to lack of technical platform. Indeed, the absence of cardiac surgery in our country is a real problem for the management of diseases requiring this surgery. The results of the myxoma excision are satisfactory with a mortality close to 1%. In the long term there is a low risk of recurrence that Shinfeld et al. [<xref ref-type="bibr" rid="scirp.101474-ref14">14</xref>] estimate from 1% to 5%. The evolution of our patient was fatal marked by death the day after the diagnosis of this myxoma either by pulmonary embolization or obstruction of the tricuspid valve.</p></sec><sec id="s4"><title>4. Conclusion</title><p>The myxoma of the right atrium is of a rare localization with a polymorphic clinical manifestation. It should be diagnosed as early as possible to avoid the occurrence of dreaded complications. Its management is surgical.</p></sec><sec id="s5"><title>Author Contribution</title><p>All authors have contributed to the improvement of this manuscript.</p></sec><sec id="s6"><title>Conflicts of Interest</title><p>The authors declare no conflicts of interest regarding the publication of this paper.</p></sec><sec id="s7"><title>Cite this paper</title><p>Sory, B.I., El Hadj Yaya, B., Abdoulaye, C., Kokoulo, K., Aly, S., Diarra, K., Morlaye, S., Demba, T., Aboubacar, C., Bassirou, B.M., Fatou, S., Mariame, B., Dadhi, B.M. and Mamady, C. (2020) Right Atrium Myxoma in an 11-Year-Old Girl in Guinea. World Journal of Cardiovascular Diseases, 10, 432-436. https://doi.org/10.4236/wjcd.2020.107042</p></sec></body><back><ref-list><title>References</title><ref id="scirp.101474-ref1"><label>1</label><mixed-citation publication-type="other" xlink:type="simple">Castillo, J.G. and Silvay, G. (2010) Characterization and Management of Cardiac Tumors. 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