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A. Kanazawa, T. Lkeda and T. Endo, “Synthesis and Antimicrobial Activity of Dimethyl- and Trimethyl-Substituted Phosphonium Salts with Alkyl Chains of Various Lengths,” Antimicrobial Agents and Chemotherapy, Vol. 38, No. 5, 1994, pp. 945-952. http://dx.doi.org/10.1128/AAC.38.5.945

has been cited by the following article:

• TITLE: Synthesis, Characterization and Performance of a New Type of Alkylene Triphenyl Double Quaternary Phosphonium Salt

  AUTHORS: Wei Wei, Bin Yuan, Song Lv, Qifeng Liao, Jieyang Huang

  KEYWORDS: Alkylene Triphenyl Phosphonium; Double Quaternary Phosphonium Salt; Bactericide; Synthesis; Performance

  JOURNAL NAME: Journal of Materials Science and Chemical Engineering, Vol.1 No.5, November 7, 2013

  ABSTRACT: ByBimolecular Nucleophilic Substitution, four new types of alkylene triphenyl double quaternary phosphonium salt were synthesized respectively by using triphenylphosphine, 1,3-dibromopropane, 1,6-dibromohexane,1,10-dibromo- decane, 1,12-dibromododecane as raw materials and using DMAC as the solvent, under a certain temperature and reac- tion time. The productivity is 58% - 83%. The molecular structures of the products were characterized by IR, NMR and elemental analysis. The sterilizing effect of 1,6-hexylidene triphenyl double phosphonium bromide(HTDPB) and 1,12- dodecylidene triphenyl double phosphonium bromide(DoTDPB) was evaluated by using extinct dilution method.The experimental result shows that the sterilizing effect of DoTDPB is better than the effect of HTDPB under the same drug concentration and contact time. When the concentration of DoTDPB was 20 mg/L and the contact time was 0.5 h, the sterilizing rate of DoTDPB used to kill saprophytic bacteria (TGB), sulfate-reducing bacteria (SRB) and iron bacteria (IB) was 95.56%, 84% and 99.58% respectively.