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C. Bertez, M. Miquel, C. Coquelet, D. Sincholle and C. Bonne, “Dual Inhibition of Cyclo-Oxygenase and Lipoxygenase by 2-Acetylthiophene 2-Thiazolye Hydrazone (CBS-1108) and Effect on Leukocyte Migration in Vivo,” Biochemical Pharmacology, Vol. 33, No. 11, 1984, pp. 1757-1762.
http://dx.doi.org/10.1016/0006-2952(84)90346-0

has been cited by the following article:

• TITLE: Novel Synthesis Approach and Antiplatelet Activity Evaluation of 6-Arylmethyleneamino-2-Alkylsulfonylpyrimidin-4(3H)-one Derivatives and Its Nucleosides

  AUTHORS: Abdulrahman G. Alshammari, Abdel-Rhman B. A. El-Gazzar

  KEYWORDS: Natural Asset; Financial Value; Neural Network

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.3 No.3A, November 6, 2013

  ABSTRACT: A new and efficient procedure has been designed for the preparation of 6-arylmethylene-amino-2-alkyl sulfonyl-pyrimidine. The first alkylthio group was introduced into the pyrimidine ring by S-alkylation. The introduction of the second one was successfully achieved using the phosphorous oxychloride method to afford 4-chloro-2-alkylthio-pyrimidines. Subsequent nucleophilic displacement by the corresponding alkylamines followed by glycoside bromide addition conveniently gave a series of the target compounds. Thus, the two same or different alkylamino groups were easily introduced into the pyrimidine ring through the two different approaches. The human anti-platelet aggregation activity of the newly synthesized compounds was also described.