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A. Monks, D. Scudiero, P. Skehan, R. Shoemaker, K. Paull, D. Vistica, C. Hose, J. Langley, P. Cronise, A. Vaigro-Wolff, M. Gray-Goodrich, H. Campbell, J. Mayo and M. Boyd, “Feasibility of a High-Flux Anticancer Drug Screen Using a Diverse Panel of Cultured Human Tumor Cell Lines,” Journal of the National Cancer Institute, Vol. 83, No. 11, 1991, pp. 757-766.
http://dx.doi.org/10.1093/jnci/83.11.757

has been cited by the following article:

• TITLE: Efficient Synthesis of a New Class of N-Nucleosides of 4H-Thiochromeno[2,3-d]pyrimidine-10-Sulfone as Potential Anticancer and Antibacterial Agents

  AUTHORS: Abdulrahman G. Alshammari, Abdel-Rhman B. A. El-Gazzar, Hend N. Hafez

  KEYWORDS: Thiochromene; Pyrimidine; Antibacterial; Anticancer Agents

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.3 No.3A, November 5, 2013

  ABSTRACT: A highly practical and efficient preparation of 6-methy-4H-thiochromene and 7-methyl-thiochromene[2,3-d]pyrimidine derivatives was developed via a multi-component reaction of 3-methyl-thiophenol (1), aldehydes (2), and malononitrile (3). A series of pyrimidine nucleoside, thiochromene[2,3-d]pyrimidine and thiochromene[2,3-d]pyrimidine-10-sulfone was efficiently obtained. These hybrid compounds were evaluated as potential antibacterial and anticancer agents and showed encouraging biological activities. Some of these derivatives showed broad-spectrum antitumour activity against the nine tumour subpanels tested, and demonstrated significant activity in the in vitro antitumour screening expressed by MG-MID log10GI50 value of －4.55, －4.67 and －4.73 of compounds 9a, 9b and 9c, respectively.