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Kleihues, P. and Cavenee, W.K. (World Health Organization) (2000) Classification of tumours. Pathology & genetics. Tumours of the nervous system. IARC Press, Lyon, 175-192.

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• TITLE: Metaplastic meningioma with pure and extensive cartilaginous transformation: A diagnostic dilemma

  AUTHORS: Oumar Coulibaly, Justin Onen, Amal Harmouch, Majhouba Boutarbouch, Adil Melhaoui, Yasser Arkha, Loubna Rifi, Said Derraz, Sanaa Sefiani, Abdessamad El Ouahabi, Abdeslam El Khamlichi

  KEYWORDS: Meningioma; Metaplastic Meningioma;Pure Cartilaginous Differentiation;Diagnostic Dilemma

  JOURNAL NAME: Case Reports in Clinical Medicine, Vol.2 No.7, October 22, 2013

  ABSTRACT: Meningiomas are the most common extra-axial central nervous system tumours and often discovered in the middle to late adult life and especially in women. About 85%-90% of meningiomas are benign, 5%-10% are intermediate-grade, and 3%-5% are malignant. Metaplastic meningioma is a rare subtype of WHO Grade I meningioma histologically characterized by the presence of mesenchymal components. The presence of pure and extensive cartilaginous differentiation in meningiomas is extremely rare and remains a diagnostic dilemma. We report, perhaps the first case of this entity in a 52-year-old woman and discuss the pathogenesis, the imaging features and the histopathologicals data.