TITLE:
Intralesional pingyangmycin injection sclerotherapy for oral ranulas
AUTHORS:
Zhifang Chen, Jiawei Zheng, Shanyong Zhang
KEYWORDS:
Ranula; Pingyangmycin; Sclerotherapy
JOURNAL NAME:
Open Journal of Stomatology,
Vol.3 No.7,
October
18,
2013
ABSTRACT:
Objective: To investigate the efficiency of pingyangmycin (PYM) intralesional injection
for the treatment of ranulas in clinical practice. Methods: PYM concentrations
were 2.0 mg/ml (8 mg PYM powder + 1 ml normal saline + 2 ml 2% lidocaine + 1 ml
dexamethasone). The mixed PYM solution was intralesional injected into ranulas
after drawing out isometric cyst fluid in 3 patients. Results: The ranulas of
3 patients showed total disappearance after the sclerotherapy, and no
recurrence was found after 6 months to 3 years’ follow-up. Compared to surgical
therapy, the PYM sclerotherapy was advocated by clinicians for its advantages
of less injury, no scar, less suffering, etc. Conclusions: PYM
is an effective sclerosing agent for ranulas. Intracystic injection of PYM
may be an optimal method for the treatment of ranulas.