TITLE:
Spot urine protein/creatinine ratio—A quick and accurate method for diagnosis of pre-eclampsia
AUTHORS:
Amita Sharma, Pandey Kiran, Bhagoliwal Ajai
KEYWORDS:
Urine Protein-Cretinine Ratio; 24 Hour Urine Proteinuria; Pre-Eclampsia; Cutoff Point
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.3 No.8,
October
18,
2013
ABSTRACT: Objective(s):To assess the diagnostic accuracy of
spot urine protein-creatinine (P/C) ratio and its compareson with 24-hour urine
proteinuria for predicting eclampsia. Method(s): Spot urine P/C ratio was determined
in a mid-stream urine sample, and the 24-hour urine protein was measured. The
correlation between the spot P/C ratio and 24-hour urine protein amount was
done. Logistic regression analysis and ROC curve analysis have been used to
analyse data. Result(s): There was a strong correlation between the spot P/C
ratio and 24-hour urine protein excretion (pearson’s correlation coefficient r
= 0.71; P specificity of 69% and 75% respectively. Conclusion(s): Spot
urine P/C ratio is a quick and reliable tool which can be used as an
alternative method for evaluation of
proteinuria for diagnosis of pre-eclampsia.