TITLE:
The “3 Genomic Numbers” Discovery: How Our Genome Single-Stranded DNA Sequence Is “Self-Designed” as a Numerical Whole
AUTHORS:
Jean-Claude Perez
KEYWORDS:
Genetic Code; Codon Populations; Junk DNA; Cancer Genomics Chromosomal Translocations; Genomes Diversity; Chromosomes Diversity; Whole Human Genome DNA Sequence; “Phi” the Golden Ratio; Fibonacci Numbers; Information Theory; Symmetry; Cellular Automata; Chargaff’s Codon Level Symmetry Principle; Fractal Self-Similarity; “e” Euler’s Number; “Pi”; form and Substance; Redundancy; Encryption
JOURNAL NAME:
Applied Mathematics,
Vol.4 No.10B,
October
4,
2013
ABSTRACT: This
article proves the existence of a hyper-precise global numerical
meta-architecture unifying, structuring, binding and controlling the billion
triplet codons constituting the sequence of
single-stranded DNA of the entire human genome. Beyond the evolution and
erratic mutations like transposons within the genome, it’s as if the memory of
a fossil genome with multiple symmetries persists. This recalls the “intermingling” of information characterizing the
fractal universe of chaos theory. The result leads to a balanced and perfect
tuning between the masses of the two strands of the huge DNA molecule that
constitute our genome. We show here how codon populations forming the
single-stranded DNA sequences can constitute a critical approach to the
understanding of junk DNA function. Then, we suggest revisiting certain methods
published in our 2009 book “Codex Biogenesis”. In fact, we demonstrate here how
the universal genetic code table is a powerful analytical filter to
characterize single-stranded DNA sequences constituting chromosomes and
genomes. We can then show that any genomic DNA sequence is featured by three numbers,
which characterize it and its 64 codon populations with correlations greater
than 99%. The number “1” is
common to all sequences, expressing the second law of Chargaff. The other 2
numbers are related to each specific DNA sequence case characterizing life
species. For example, the entire human genome is characterized by three remarkable
numbers 1, 2, and Phi = 1.618 the golden ratio. Associated with each of these
three numbers, we can match three axes of symmetry, then “imagine” a kind of
hyperspace formed by these codon populations. Then we revisit the value (3-Phi)/2
which is probably universal and common to both the scale of quarks and atomic
levels, balancing and tuning the whole human genome codon population. Finally,
we demonstrate a new kind of duality between “form and substance” overlapping
the whole human genome: we will show that—simultaneously with the duality
between genes and junk DNA—there is a second layer of embedded hidden structure
overlapping all the DNA of the whole human genome, dividing it into a second
type of duality information/redundancy involving golden ratio proportions.