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K.-B. Kwon, E.-K. Kim, B.-C. Shin, E.-A. Seo, J.-Y. Yang and D.-G. Ryu, “Herba Houttuyniae Extract Induces Apoptotic Death of Human Promyelocytic Leukemia Cells via Caspase Activation Accompanied by Dissipation of Mitochondrial Membrane Potential and Cytochrome c Release,” Experimental and Molecular Medicine, Vol. 35, No. 2, 2003, pp. 91-97.

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• TITLE: Houttuynia cordata Thunb: A Review of Phytochemistry and Pharmacology and Quality Control

  AUTHORS: Jiangang Fu, Ling Dai, Zhang Lin, Hongmei Lu

  KEYWORDS: Houttuynia cordata Thunb; Phytochemical Constituents; Pharmacological Activity; Quality Control

  JOURNAL NAME: Chinese Medicine, Vol.4 No.3, September 24, 2013

  ABSTRACT: Houttuynia cordata Thunb is an important medicinal plant widely distributed in East Asia. The collected information is an attempt to cover recent developments in the pharmacology, phytochemistry and quality control of this species. During the past several decades, the medicinally important phyto-constituents have been identified including essential oil, flavonoids and other polyphenols, fatty acids and alkaloids. A survey of the literatures shows H. cordata possesses a variety of pharmacological activities including antiviral, antitumor, antimicrobial, anti-inflammatory, and antioxidative effects. Little attempt has been done to review the techniques used for its quality control. Future efforts should concentrate more on in vitro, in vivo studies and clinical trials in order to confirm traditional wisdom in the light of a rational phytotherapy. The information summarized here is intended to serve as a reference tool to practitioners in the fields of ethnopharmacology and natural products chemistry.