TITLE:
Impact of urinary tract and pulmonary infection on mortality after intracerebral hemorrhage in Brazzaville
AUTHORS:
P. M. Ossou-Nguiet, B. F. Ellenga-Mbolla, A. S. W. Odzebe, G. F. Otiobanda, T. N. Gankama, K. Obondzo-Aloba, T. R. Gombet
KEYWORDS:
Infection; Cerebral Hemorrhage; Mortality; Sub-Saharan Africa
JOURNAL NAME:
World Journal of Neuroscience,
Vol.3 No.4,
September
23,
2013
ABSTRACT: Objective: To evaluate the impact of urinary tract
and pulmonary infection on mortality after cerebral hemorrhage. Method: We conducted
at the University Hospital of Brazzaville, a cross-sectional study from January
to August2012 inthe
emergency department, neurology and intensive care unit. It included patients
admitted for cerebral hemorrhage confirmed by CT-scan. A statistical analysis
by logistic regression was carried out to evaluate the correlation between
infection and death. Result: Among total of 261 patients for stroke, 82
admitted for cerebral hemorrhage (31.4%). The mean age was 55 ± 11 years (range
26 to 83 years). The sex ratio men/women was 1.7. Hypertension was the most important
risk factor to 80.5%. The average intake in neurology time was 28 ± 13 hours.
The average time for completion of the CT-scan was 2.4 ± 2 days. Thirty-eight
(46.3%) patients had a fever linked to an infectious cause from the third day
of hospitalization. The most frequent infectious complications were sepsis (n =
16%; 42%), pulmonary infection (n = 14%; 37%) and urinary tract infection (n =
8%; 21%). Specific mortality of infection was 31.7% (n = 26). The multivariate
analysis showed a positive correlation between the occurrence of infection and
mortality (p = 0.002), specifically between sepsis and mortality (p = 0.0004),
and an association between the time of admission late in neurology and the
occurrence of infectious complications (p = 0.0001). Conclusion: Infection is
one of the dreaded complications of cerebral hemorrhage. It is often associated with delayed care in specialized areas,
and is thereby a preventable cause of death.