Article citationsMore>>

H.-H. Sun, W.-J. Mao, Y. Chen, S.-D. Guo, H.-Y. Li, X.-H. Qi, Y.-L. Chen and J. Xu, “Isolation, Chemical Characteristics and Antioxidant Properties of the Polysaccharides from Marine Fungus Penicillium sp. F23-2,” Carbohydrate Polymers, Vol. 78, No. 1, 4, 2009, pp. 117- 124.

has been cited by the following article:

• TITLE: Assessment of Secondary Metabolites from Marine-Derived Fungi as Antioxidant

  AUTHORS: Nihad Abdel-Monem, Ahmed M. Abdel-Azeem, E. S. H. El Ashry, Doaa A. Ghareeb, Asmaa Nabil-Adam

  KEYWORDS: DPPH; TBARS; Marine Drugs; Marine Derived Fungi; Anti-Inflammatory; Antioxidant Capacity

  JOURNAL NAME: Open Journal of Medicinal Chemistry, Vol.3 No.3, September 20, 2013

  ABSTRACT: Marine derived fungi are considered as a promising source of novel drugs due to their biodiversity and consequent chemo-diversity. Although marine microorganisms especially fungi are not well defined taxonomically, making this a promising frontier for the discovery of new medicines. This study focused on marine derived fungi as a model for bioactive exploration for new entities with anti-inflammatory and antioxidant capacity. Three in-vitro assays were used to investigate the bioactive antioxidant potentiality of fungal extracts. Thiobarbituric acid (TBARS),α,α-Diphenyl-β- picrylhydrazyl (DPPH) and NO assay are based on their total phenolic and flavonoid content of each extract group. Ch. globosum recorded the highest antioxidant activity (92.82%) in TBARS assay, while G. dankaliensis came first by recording 59.28% in DPPH assay in comparison with ascorbic acid (61.83%). In NO inhibition assay, N. oryzae showed 49.3% comparing with ascorbic acid (73.12%). From the preliminary result of our extracts, we can consider the marine derived fungi extracts as promising antioxidant and anti-inflammatory drug candidate.