Article citationsMore>>

D. A. Evans, H. P. Ng and D. L. Rieger, “Total Synthesis of the Macrolide Antibiotic Rutamycin B,” Journal of the American Chemical Society, Vol. 115, No. 24, 1993, pp. 11446-11459. doi:10.1021/ja00077a049

has been cited by the following article:

• TITLE: Convenient Cleavage Reaction of 1-Acylhydantoin to Amide

  AUTHORS: Jun-ichi Yamaguchi, Kanako Nozaki Abe, Takao Narushima

  KEYWORDS: Amides; Acylhydantoin; Chiral Auxiliaries; Cleavage; Lewis Acid

  JOURNAL NAME: International Journal of Organic Chemistry, Vol.3 No.3, September 4, 2013

  ABSTRACT: A cleavage reaction of 1-acylhydantoin by an amine in tetrahydrofuran at elevated temperature provided the corre-sponding amide and hydantoin in high yield. It was found that the addition of diethylaluminum chloride accelerated the cleavage reaction rate. The amide yield depended on the steric hindrance of the amine.