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has been cited by the following article:
TITLE: Convenient Cleavage Reaction of 1-Acylhydantoin to Amide
AUTHORS: Jun-ichi Yamaguchi, Kanako Nozaki Abe, Takao Narushima
KEYWORDS: Amides; Acylhydantoin; Chiral Auxiliaries; Cleavage; Lewis Acid
JOURNAL NAME: International Journal of Organic Chemistry, Vol.3 No.3, September 4, 2013
ABSTRACT: A cleavage reaction of 1-acylhydantoin by an amine in tetrahydrofuran at elevated temperature provided the corre-sponding amide and hydantoin in high yield. It was found that the addition of diethylaluminum chloride accelerated the cleavage reaction rate. The amide yield depended on the steric hindrance of the amine.