TITLE:
Endometrioid adenocarcinoma arising from abdominal wall endometriosis in the appendectomy scar: A case report
AUTHORS:
Masaru Hayashi, Akiko Shoda, Nobuaki Kosaka, Masaru Kojima, Nobuhide Masawa, Ichio Fukasawa
KEYWORDS:
Abdominal Wall Endometriosis; Appendectomy Scar; Malignant Transformation; Endometrioid Adenocarcinoma
JOURNAL NAME:
Open Journal of Obstetrics and Gynecology,
Vol.3 No.7,
August
26,
2013
ABSTRACT: We
report a very rare case of endometrioid adenocarcinoma arising from abdominal
wall endometriosis in the appendectomy scar. A 47-year-old woman visited the
surgical department, since she had a gradually growing and painful tumor both
in an appendectomy scar and at an umbilical site. She underwent appendectomy at
age 18 years, and noticed the tumor at age 22 years. Partial tumor resection
was performed in that department, and the pathology revealed endometrioid
adenocarcinoma. She was referred to our department for radical therapy. Tumors
in the both sites were dissected together with some swelling lymph nodes in our
department. A pathological diagnosis of the tumor in the umbilical site showed
only benign endometriosis. In contrast, the tumor in the appendectomy scar
showed benign endometriosis, atypical endometriosis and well differentiated endometrioid
adenocarcinoma. Resected lymph nodes also contained endometrioid adenocarcinoma,
and were diagnosed as metastases. It was concluded that the endometrioid
adenocarcinoma in the tumor of the appendectomy scar was a malignant
transformation arising from abdominal wall endometriosis from the pathological
findings. Since the operation, adjuvant and maintenance chemotherapy with paclitaxel
and carboplatin had been administered for 3 years. She is free of disease 3.5
years after the operation.