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T. Jaarsma, J. M. Beattie, M. Ryder, F. H. Rutten, T. McDonagh, P. Mohacsi, S. A. Murray, T. Grodzicki, I. Bergh, M. Metra, I. Ekman, C. Angermann, M. Leventhal, A. Pitsis, S. D. Anker, A. Gavazzi, P. Ponikowski, K. Dickstein, E. Delacretaz, L. Blue, F. Strasser and J. McMurray, “Palliative Care in Heart Failure: A Position Statement from the Palliative Care Workshop of the Heart Failure Association of the European Society of Cardiology,” European Journal of Heart Failure, Vol. 11, No. 5, 2009, pp. 433-443. doi:10.1093/eurjhf/hfp041

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• TITLE: Improved Hemolytic Performance of Blood Pump with Fluorine-Doped Hydrogenated Amorphous Carbon Coating

  AUTHORS: Yasuharu Ohgoe, Masanori Hiratsuka, Hirohito Sumikura, Kazuyoshi Fukunaga, Akihiko Homma, Kenji K. Hirakuri, Akio Funakubo, Yasuhiro Fukui

  KEYWORDS: Fluorine-Doped a-C:H Film; Hemolytic Performance; Artificial Heart Blood Pump

  JOURNAL NAME: Advances in Chemical Engineering and Science, Vol.3 No.3A3, August 23, 2013

  ABSTRACT: Fluorine-doped hydrogenated amorphous carbon (a-C:H:F) film was deposited on a flow-straightener, impeller and diffuser surface (SUS 304) of an enclosed-impeller type flow blood pump using the ionization deposition method with a source gas of C6F5H. The surface characteristics of the a-C:H:F film were examined using atomic force microscopy, X-ray photoelectron spectroscopy, and measurements of surface roughness, friction and surface potential. The a-C:H:F film tends to increase surface roughness and the negative surface charge. In addition, the surface energy and friction decrease with fluorine dopant in the a-C:H film. To estimate the hemolytic performance of a blood pump with the a-C:H:F film coating, the amount of hemolysis was measured using a mock circulatory system (in vitro test) with 500 mL of pig blood containing sodium citrate. In vitro test was conducted for 180 min with the blood flow and pump head maintained at 5 L/min and 100 mmHg, respectively. The a-C:H:F film coating reduced the amount of hemolysis and improved the hemolytic performance. Decreasing the surface energy and negative surface charge of the a-C:H:F film contributes to the improvement of the hemolytic performance. The a-C:H:F film coating is thus expected to be utilized in medical technology as a surface coating technology for artificial heart blood pumps.